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Constitutive Signaling by AKT1 E17K in Cancer
SuperPath
Pathway network
for
Constitutive Signaling by AKT1 E17K in Cancer
SuperPath
5
Pathways
in the
Constitutive Signaling by AKT1 E17K in Cancer
SuperPath
AKT phosphorylates targets in the nucleus
Constitutive Signaling by AKT1 E17K in Cancer
Class I PI3K signaling events mediated by Akt
AKT phosphorylates targets in the cytosol
AKT-mediated inactivation of FOXO1A
38
Genes
in the
Constitutive Signaling by AKT1 E17K in Cancer
SuperPath
AKT3
AKT1
AKT2
FOXO1
CDKN1A
CDKN1B
CHUK
GSK3B
BAD
CASP9
CREB1
FOXO3
NR4A1
FOXO4
RPS6KB2
MTOR
RICTOR
GSK3A
MDM2
PDPK1
MLST8
TSC2
MAPKAP1
AKT1S1
PRR5
RAF1
HSP90AA1
SRC
PRKACA
SFN
SLC2A4
YWHAZ
PRKDC
BCL2L1
MAP3K5
TBC1D4
KPNA1
MKRN1
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network
for
Constitutive Signaling by AKT1 E17K in Cancer
SuperPath