ERK Signaling SuperPath

Pathway network for ERK Signaling SuperPath
1177 Genes in the ERK Signaling SuperPath
ACAN ALK ANGPTL6 AREG AXL BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5
BMP6 BMP7 BMP8A BTC COL10A1 COL11A1 COL11A2 COL12A1 COL13A1 COL14A1 COL15A1 COL16A1
COL17A1 COL18A1 COL19A1 COL1A1 COL1A2 COL21A1 COL22A1 COL23A1 COL24A1 COL25A1 COL27A1 COL2A1
COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2
COL6A3 COL7A1 COL8A1 COL8A2 COL9A1 COL9A2 COL9A3 HAPLN1 CSF1R VCAN NCAN SMC3
CTGF CXCL12 DDR1 DDR2 EPYC LEFTY2 TYMP ECM1 ECM2 EFEMP1 EFEMP2 EGF
EGFR ELN EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3
EPHB4 EPHB6 EPOR ERBB2 ERBB3 ERBB4 FBN1 FBN2 FBN3 FGF1 FGF10 FGF11
FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23
FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 VEGFD FLT1 FLT3
FLT4 FN1 FOS FRAS1 GAS1 GAS2 GAS6 GAS8 GDF10 GDF2 GDF5 GDF6
GDF9 GFER GH1 GH2 GHRH GMFG GNRH1 GNRH2 GPC6 HAPLN2 HAPLN3 HAPLN4
HDGF HGF HSPG2 IGF1 IGF1R IGF2 IGF2-AS IL2 IL3 IL6 IL9 IMPG1
IMPG2 INSR INSRR ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3
ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 JUN KDR COL20A1 KIT KITLG LAMA1 LAMA2
LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 LEFTY1 LHB
LIFR LMTK2 LMTK3 LTBP1 LTBP2 LTBP3 LTBP4 MAPK1 MAPK3 MDK MEPE MERTK
MET MMRN2 MST1R MUSK NFKB1 NGF NRG1 NRG2 NRG3 NTF3 NTF4 NTRK1
NTRK2 NTRK3 NUDT6 OGN PIK3R5 PDGFA PDGFB PDGFC PDGFRA PDGFRB PENK PGF
PIK3R1 PIK3R2 PIK3R3 PIK3R4 GDF15 PLPP3 PPBP PRG2 PRG4 PROK1 PSIP1 PTK2
PTK2B PTK7 PTN RAC1 ROR1 ROR2 ROS1 RYK PDGFD CLEC11A SEMA3A SEMA4B
SEMA4G SEMA5A SPOCK1 SPOCK2 SPOCK3 SPON1 SPON2 SPP1 TBRG1 TDGF1 TEK TGFA
TGFB1 TGFB2 TGFB3 THPO TIE1 KLF10 TIMP1 TIMP2 TIMP3 TIMP4 TNC TNF
TYRO3 UTS2 VEGFB VEGFC CDC42 MAPK10 MAPK8 MAPK9 MYC BCL2 ELK1 GNA11
GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAT1 GNAT2
GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3
GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 IL1A IL1B ITGA1 ITGA10 ITGA11 ITGA2
ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 LTA MAP2K1 MAP2K2 OSM
PAK1 RAF1 RHOA RHOB RHOC RHOD RND3 RHOG ARHGEF6 RHOH DIRAS3 RND2
ATF1 ATF4 BAD CDH1 CHUK CREB1 CREB3 CREB3L4 RAC2 RAC3 RPS6KA4 RPS6KA5
TCF3 TCF4 TNFRSF1A ANGPT1 ANGPT2 ANGPT4 ANGPTL1 BAX BMP15 BMP8B BTK CCL1
CCL11 CCL13 CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL2 CCL20 CCL21 CCL22
CCL23 CCL24 CCL25 CCL26 CCL27 CCL28 CCL3 CCL3L1 CCL4 CCL4L1 CCL4L2 CCL5
CCL7 CCL8 CD2 CD80 CER1 CSF1 CSF2 CSF3 CX3CL1 CXCL1 CXCL10 CXCL11
CXCL13 CXCL14 CXCL16 CXCL2 CXCL3 CXCL5 CXCL6 CXCL9 DAP IL10 IL11 IL12A
IL12B IL13 IL15 IL16 IL17A IL18 IL19 IL20 IL21 IL22 IL23A IL24
IL26 IL4 IL5 IL7 CXCL8 LIF MAP2K3 MAP2K6 MAP2K7 PAK2 PAK3 PAK4
PAK6 PAK5 PF4 PF4V1 PIP PPBPP2 PRKCI PRKCZ TNFSF10 TNFSF11 TNFSF12 TNFSF13
TNFSF13B TNFSF14 TNFSF18 TNFSF4 CD40LG FASLG CD70 TNFSF8 TNFSF9 ADCY1 ADCY2 ADCY3
ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 BRAF GRB2 HRAS KRAS MRAS NRAS
PLCB1 PLCB2 PLCB3 PLCB4 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA
PRKCB PRKCD PRKCE PRKCG PRKCH PRKD1 PRKD3 PRKCQ RAP1A RAP1B RRAS RRAS2
SOS1 SOS2 SRC TP53 AKT1 AKT2 AKT3 ATF2 ATF3 ATF5 ATF6 ATF7
BCAR1 GCFC2 CASP3 CASP9 CCND1 CDH10 CDH11 CDH12 CDH13 CDH15 CDH16 CDH17
CDH18 CDH19 CDH2 CDH3 CDH4 CDH5 CDH6 CDH7 CDH8 CDH9 CEBPB CFL1
CFL2 CTNNB1 MTOR GSK3A GSK3B HIF1A HNF4A IRS1 LEF1 MAPK6 MYL9 NFE2L1
PDPK1 PPP1R14B PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R2B PPP2R2C PPP2R3A PTPA PPP2R5A
PPP2R5B PPP2R5C PPP2R5E PPP2R3B PTEN PXN HNF1A TCF12 TCF15 TCF19 HNF1B TCF20
TCF21 TCF23 TCF7 TCF7L2 ZEB1 TEAD1 TEAD4 TFAM VIM ZNF354A ARHGEF1 ARHGEF10
ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF2 ARHGEF3 ARHGEF4 ARHGEF5 ARHGEF7 ARHGEF9 MAP2K4 MAP2K5
MAP3K10 MAP3K11 MCF2L MYLK NET1 PPP1R12A PPP1R12B ARAF CNKSR1 IL1R1 IL2RA LAMTOR3
MAP3K5 MAP3K7 MAPK11 MAPK12 MAPK13 MAPK14 MAPK7 MKNK1 MKNK2 NGFR PLCG1 RPS6KA1
RPS6KA2 RPS6KA3 RPS6KA6 STAT1 STAT3 TGFBR1 TNFRSF1B TRADD ELK3 ELK4 MAX NFKBIA
TUBB2A ACTA1 ACTA2 ACTB ACTG1 ACTG2 ACTN1 ACTN2 ACTN3 ACTN4 RHOJ RHOQ
CDH20 CDH22 CDH23 CDH24 CDH26 DOCK1 DSP FBLIM1 FLNA FLNB FLNC FOSB
FOSL1 FOSL2 MYLPF ILK IRS2 IRS4 JUNB JUND MYH15 KRT18 LIMS1 LIMS2
CLEC18C MUC1 MYH1 MYH10 MYH11 MYH13 MYH14 MYH2 MYH3 MYH4 MYH6 MYH7
MYH7B MYH8 MYH9 MYL1 MYL2 MYL3 MYL4 MYL5 MYL6 MYL7 MYO10 MYO15A
MYO18B MYO1A MYO1B MYO1C MYO1D MYO1E MYO1F MYO1G MYO3A MYO3B MYO5A MYO6
MYO7A MYO9A MYO9B NACA NCK2 NOS2 PARVA PARVB DCHS1 FERMT2 PPP2R5D PTGS2
RSU1 SNAI1 SNAI2 TESK1 TGFB1I1 TMSB4X TMSB4Y VEGFA PCDH9-AS3 PCYT1B-AS1 ACTR2 ACTR3
ARFIP2 ARHGDIA ARHGDIB BAIAP2 SEPT7 CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 CDC42EP5 CIT CYFIP1
DES DIAPH3 GFAP IQGAP1 LIMK1 LIMK2 MAP3K9 SEPT9 MSN NCF2 SEPT2 PARD3
PARD6A PIP5K1A PIP5K1B PIP5K1C PIP4K2A PIP4K2B PIP4K2C PLD1 SEPT5 SEPT4 PKN1 RDX
ROCK1 ROCK2 CLIP1 SLC9A1 STMN1 EZR WASF1 WASF3 WASL WIPF1 CLEC14A DDIT3
HBEGF GLG1 HSF1 IGF2R IL1R2 IRAK1 IRAK2 IRAK3 IRAK4 MAP3K2 MAP3K3 MAP3K4
MAP3K8 MAPK8IP1 MAPK8IP2 MAPK8IP3 MAPKAPK2 MEF2A MEF2C MEF2D NRP1 NRP2 OGFR PLCD1
PLCD3 PLCD4 PLCE1 PLCG2 PLCZ1 WNK1 RIPK1 SH3RF1 STAT2 STAT4 STAT5A STAT5B
STAT6 TGFBR3 TLN1 TLN2 TRAF2 TRAF6 VCL BRF1 CACNA1A CACNA1B CACNA1C CACNA1D
CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2
CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 CAPN1 CAPN10
CAPN11 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7 CAPN9 CAPNS1 CD3D CD3E CD3G CD247
DUSP1 DUSP3 ESR1 ESR2 ETS1 ETS2 H3F3A H3F3B HIST1H3A HIST1H3B HIST1H3C HIST1H3D
HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST3H3 HMGN1 LAT PAX6 PPP1R10 PPP1R11
PPP1R12C PPP1R13B PPP1R14A PPP1R15A PPP1R16A PPP1R1A PPP1R1B PPP1R2 PPP1R3A PPP1R3B PPP1R3C PPP1R3D
PPP1R3F PPP1R7 PPP1R8 PPP1R9A PPP1R9B SRF TP53BP2 UBTF ZAP70 ABL1 ABL2 ACVR1
ACVR2B ACVRL1 ADAM17 APAF1 APC APH1A ATM ATR AURKB AURKC AXIN1 BAK1
BBC3 BCL2L1 BCL2L11 BID BIRC2 BIRC3 CXCR5 BMPR1A BMPR1B BMPR2 BRCA1 CAMK2A
CAMK2B CAMK2D CAMK2G CASP10 CASP6 CASP7 CASP8 CBL CCND2 CCND3 CCNE1 CCNE2
CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCRL2 CD28 CD4
CDK1 CDC25A CDC25B CDC25C CDK2 CDK4 CDK6 CDKN1A CDKN1B CDKN2A CDKN2B CDKN2C
CDKN2D CFLAR CHEK1 CHEK2 CREBBP CRK CSF2RA CSF2RB CSF3R CTNNA1 CTNNA2 CTNNA3
CTNND1 CX3CR1 CXCR3 CXCR4 CXCR6 CYCS DHH DVL1 E2F1 E2F2 E2F3 E2F4
E2F5 EP300 FADD FANCD2 FOXO1 FPR2 FYN FZD1 FZD10 FZD2 FZD3 FZD4
FZD5 FZD6 FZD7 FZD8 FZD9 GAB1 GAB2 GLI1 GNB1L RACK1 CCR10 HAT1
HIPK2 HRH4 IHH IL10RA IL10RB IL11RA IL12RB1 IL12RB2 IL13RA1 IL13RA2 IL15RA IL17RA
IL17RC IL18R1 IL20RA IL22RA1 IL23R IL2RB IL2RG IL3RA IL4R IL5RA IL6R IL7R
CXCR1 CXCR2 IL9R JAK1 JAK2 JAK3 LRP5 LRP6 SMAD1 SMAD2 SMAD3 SMAD4
SMAD5 SMAD9 TAB1 TAB2 MDM2 NBN NCSTN NF1 NFKBIB NFKBIE NLK NOTCH1
NOTCH2 NOTCH3 NOTCH4 NUMB OSMR PSENEN PIK3C2G PIK3CG PMAIP1 PRKAA1 PRKAA2 PRKAB1
PRKAB2 PRKAG1 PRKAG2 PRKAG3 PRKDC PSEN1 PSEN2 APH1B PTCH1 PTCH2 RAD51 RALA
RALB RALBP1 RALGDS RAP2A RAP2B RAP2C RAPGEF1 RARA RARB RARG RASA1 RASGRF1
RASGRF2 RASGRP1 RASGRP2 RB1 RBL1 RBPJ RHEB NPTN DIABLO SMO SOX1 SOX10
SOX11 SOX12 SOX13 SOX14 SOX15 SOX17 SOX18 SOX2 SOX21 SOX3 SOX30 SOX4
SOX5 SOX6 SOX7 SOX8 SOX9 STK11 STK36 AURKA SUFU SYNGAP1 TGFBR2 TNFAIP6
TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF11A TNFRSF25 TNFRSF12A TNFRSF13B TNFRSF13C TNFRSF14 TNFRSF17 TNFRSF18
TNFRSF21 TNFRSF4 CD40 FAS TNFRSF6B CD27 TNFRSF8 TNFRSF9 TSC1 TSC2 TUBA4A TUBA3C
TUBA8 TUBB1 TUBB3 TUBB7P TUBD1 TUBE1 TUBG1 TUBG2 VHL WEE1 WNT1 WNT5A
XCR1
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network for ERK Signaling SuperPath