ERK Signaling SuperPath

Pathway network for ERK Signaling SuperPath
1251 Genes in the ERK Signaling SuperPath
PRG4 PRG2 HAPLN2 HAPLN3 PROK1 HAPLN1 GDF15 GDF5 GDF2 GDF9 FIGF CXCL12
BP2 PSIP1 LPPR3 LPPR2 MST1R ANGPTL6 CXXC1 GMFG ELN GDF6 GDF10 SPOCK2
SPON2 SPOCK3 SPP1 FN1 PENK PIK3R2 PIK3R5 PIK3R3 SPOCK1 SPON1 MMDK MMRN2
PPBP UTS2 LIFR PPAP2B TEK FRAS1 MUSK MEPE MERTK IL3 IL6 IL9
BMP1 IL2 ITGB5 ITGAM ITGAV ITGAD ITGB6 BMP8A BMP3 BMP5 GHRH GH2
GH1 BMP4 BMP7 BMP10 BMP2 BMP6 TNNC1 ITGB4 DDR1 MICD NTRK2 NTF4
DDR2 HDGF MET HAPLN4 FOS NTRK1 NTRK3 ITGAE ITGAX ITGB1 ITGB8 ITGB7
ITGB3 NTF3 ACAN ITGB2 PIK3R1 PIK3R4 GNRH2 GNRH1 SEMA4G SEMA3A TGFB2 TGFB3
LAMC3 LAMA2 TGFA TGFB1 SEMA5A SEMA4B LMTK2 EFEMP1 EFEMP2 PGF LMTK3 CLEC11A
KDR VEGFC VEGFB LAMB1 LAMA1 PTK2 PTN TIMP3 TIMP2 PTK7 PTK2B TNF
TNC HSPG2 TIMP1 TIE1 LAMB3 LAMC1 LAMA5 LAMC2 LAMA3 LAMB4 TIMP4 LAMA4
LAMB2 FBN3 JUN EPHA5 EPHB4 EPHA7 INSRR EPHA4 EPHB1 EPHB3 EPHA2 EPYC
GPC6 ECM2 IGF2-AS TYMP TYRO3 THPO IGF1 IGF1R ECM1 HLA-DPB2 IGF2 EPHB2
EPOR GFER FLT3 LEFTY1 LEFTY2 FLT4 NGF FBN1 FLT1 FBN2 NUDT6 VCAN
EPHA3 EPHA1 EPHA8 EPHB6 RNASE1 INSR RNMT SMC3 LHB COL11A2 ITGAL PDGFA
PDF PDGFB PDGFRB PDGFRA IMPG1 PDGFD PDGFC LTBP4 AXL LTBP2 LTBP3 IMPG2
LTBP1 ROS1 ROR1 FGF8 FGF13 FGF4 CSF1R HGF FGF1 FGF7 ERBB3 AREG
RYK ROR2 ALK FGFR2 SLTM SLC25A12 NCAN GAS8 S1PR1 GAS1 GAS2 TBRG1
KIT KITLG NFKB1 ERBB2 ERBB4 FGF10 OGN KLF10 GAS6 MDK NRG2 PXDN
CTGF BTC BDNF BDNF-AS EGF NRG1 TDGF1P3 TDGF1 RAC1 EGFR NRG3 FGF23
FGF20 COL4A4 COL16A1 COL13A1 COL10A1 COL21A1 COL4A6 COL1A1 FGF17 COL25A1 COL4A1 COL23A1
COL4A5 COL9A2 COL11A1 COL4A3 COL19A1 COL5A2 COL15A1 COL7A1 FGF11 FGF16 FGF22 COL8A1
COL6A1 COL5A1 COL5A3 COL18A1 COL20A1 COL4A2 COL12A1 COL6A3 COL3A1 COL9A3 COL14A1 COL9A1
FGF18 COL2A1 FGFR4 COL17A1 COL27A1 COL1A2 FGF21 FGF6 FGF5 FGF12 FGF19 MAPK3
COL8A2 COL22A1 FGFR3 MAPK1 COL24A1 COL6A2 FGF14 FGF2 FGFR1 ITGA1 ITGA6 ITGA7
ITGA8 ITGA11 ITGA9 GNG4 GNGT1 ITGA5 OSM ITGA4 RAF1 ITGA2B ITGA3 ITGA2
CDC42 GNB5 GNA14 GNB2 GNG5 GNA15 ITGA10 GNG3 GNAO1 GNG11 GNAI1 GNAT2
GNAI3 GNAZ GNG7 GNG10 CCM2 MAP2K2 GNAS IL1B LTA GNG2 GNG13 GNA13
GNA11 GNGT2 GNB1 PAK1 GNG8 IL1A GNB4 MAPK9 MAPK8 MAPK10 GNA12 GNAI2
GNAT1 MAP2K1 BCL2 ELK1 GNG12 GNB3 MYC GNAL IL17A PLCB2 MAP2K3 MAP2K6
PLCB3 MAP2K7 GRB2 PLCB1 CSF2 CD40LG ATF4 ATF1 IL4 BMP15 PRKCZ DNPEP
IL16 IL5 IL18 IL13 PLCB4 IL20 IL24 BMP8B IL21 CD80 C3CER1 RA1
RAP1A IL11 RA2 RAP1B IL17B NRAS BTK CSF1 PAK2 PAK6 IL26 CD2
PAK4 CSF3 IL7 IL12B IL8 IL23A IL12A PRKCI IL19 HRAS PKN2 PAK7
IL22 BAX CD70 IL10 IL15 PAK3 PRKACG ADCY4 ADCY9 ADCY1 ADCY2 FASLG
ADCY6 ADCY7 ADCY8 RPS6KA4 PF4 RPS6KA5 LIF ADCY5 ADCY3 DIRAS3 TCF7L1 PRKCG
CHUK PRKCQ PRKD1 KRAS PRKCD TNFRSF1A PRKAR2B TCF4 PRKACA PRKAR2A PRKCA PRKACB
TCF3 PF4V1 BRAF TNFSF13 TP53 CDH1 TNFSF14 RRAS RRAS2 TNFSF10 TNFSF4 TNFSF13B
ARHGEF6 TNFSF12 TNFSF9 TNFSF18 TNFSF11 TNFSF8 SOS1 RAC2 RAC3 CREB3L4 CREB3 SOS2
CREB1 RHOH RHOG RHOC BAD RHOD RHOA RHOB PRKCB PRKCH MRAS CCL20
CCL18 DAP CCL28 RND3 CCL3L1 CCL2 CCL7 CCL17 CCL3 PIP CCL15 CCL4L2
PRKAR1A CCL24 CCL8 RND2 CCL14 CCL23 CCL11 CCL27 CCL21 CCL13 CCL4 CCL22
CCL4L1 CCL16 CCL25 CCL19 CCL1 CCL26 PPBPP2 SRC CCL5 CXCL13 CXCL3 CXCL16
BPNT1 CXCL5 CXCL1 CXCL6 CX3CL1 CXCL11 PRKCE PRKAR1B PRKD3 IAPP CXCL9 CXCL10
CXCL14 CXCL2 ANGPT4 ANGPT2 CER1 ANGPT1 ANGPTL1 MAP2K5 NET1 IL2RA RAPGEF3 MAP2K4
TNFRSF1B PPP1R12A PPP1R12B IL1R1 NFKBIA MAP3K10 MAP3K11 ARAF MAPK14 PRPF38B ELK4 MAPK11
ELK3 MAP3K7 TSPAN1 MAPK13 MCF2L MYLK MAPK12 TGFBR1 MAPK7 MAX NGFR MAP3K5
TFAM CEBPB PPP2R3B PPP2R2C PPP2CA ZEB1 ARHGEF7 ARHGEF1 PPP2R5B AKT3 AKT2 PPP2R2A
PPP2R5A TCF7 PPP2R4 TCF20 PPP2R2B PPP1R14B ARHGEF15 ARHGEF2 MTOR CCND1 PLCG1 SLC6A2
SLC6A5 RPS6KA3 RPS6KA2 TRADD ARHGEF10 ARHGEF5 ARHGEF11 ARHGEF3 ARHGEF4 ARHGEF9 ARHGEF16 ARHGEF12
PPP2R1B PPP2CB HIF1A PTEN VPS72 TCF21 LEF1 CFL2 CFL1 IRS1 GCFC2 MKNK2
MYLPF MYL9 MKNK1 VIM LAMTOR3 MYL12B TCF15 STAT3 PPP2R3A PPP2R1A TEAD1 TCF19
TCF23 PPP2R5E PPP2R5C STAT1 TEAD4 TCF7L2 TCF12 ATF3 ATF2 ATF5 ATF7 ATF6
RPS6KA1 AKT1 CDH19 CDH13 CDH8 CDH16 CDH17 PXN NFE2L1 HNF4A PDPK1 GSK3A
GSK3B CDH4 CDH7 CDH5 RPS6KA6 CDH18 CDH2 CDH9 CDH11 CDH10 CDH12 CDH6
CDH15 HNF1A CDH3 CTNNB1 ZNF354A BCAR1 CASP3 CNKSR1 HNF1B CASP9 MAPK6 CYCS
LRP6 TUBB1 LRP5 PPP1R3B TUBE1 PPP1R7 PPP1R3F PPP1R2 PPP1R14A AURKB CFLAR MAP3K4
MAPK8IP2 MAP3K3 SMAD7 MAP3K8 DDIT3 MAPK8IP3 AURKC GPI SMOX SMAD2 TUBA3C TNFRSF13C
TUBA3D OGFR TNFRSF6B NRP1 MAPKAPK2 GLG1 TUBG2 TRAF6 RIPK1 TUBB TUBB7P NRP2
TUBB4B PPP1R13B TUBB3 IGK PPP1R1A TUBA8 MAP3K2 MAPK8IP1 TNFRSF4 TRAF2 PPP1R8 AURKA
TNFRSF10A GNB2L1 PLCD4 PLCD3 IL1R2 MEF2A PPP1R10 NELL2 HBEGF HSF1 TGFBR3 CLEC14A
VCL NELL1 IRAK1 STAT5A STAT2 MEF2D WNK1 MEF2C STAT6 STAT5B IRAK4 IRAK3
IRAK2 STAT4 GNB1L SH3RF1 TNFRSF10B TNFRSF21 PLCZ1 IGF2R PLCE1 TNFRSF9 SMAD4 PLCG2
TNFRSF8 SMAD1 SMAD6 TLN2 TLN1 TNFRSF11A SMAD3 NBN NUMB PMAIP1 TNFRSF12A SMAD5
SMAD9 TNFRSF13B TNFRSF10C SMO PLCD1 HIST1H3D CACNA2D1 CAPN11 CACNA1D PARD6A PARD3 CACNG6
CACNG5 CACNA1F CLIP1 SEPT9 CIT EZR CACNG7 SEPT5 SEPT2 SEPT4 SEPT7 CACNA1I
WASL CACNB4 CAPNS1 CACNG1 LIMK2 LIMK1 DHDDS DIAPH3 PRKCSH CAPN10 CACNA1E CAPN6
CAPN9 WASF1 CACNA1S WASF3 CACNA2D2 CAPN5 CACNB2 GFAP TARP UBTF CAPN3 ZAP70
ENTHD1 CD3E CD3D CD3G HMGN1 CAPN2 CACNA1B CACNA1H CACNA1G CACNB3 CACNA1A H3F3A
H3F3B CD247 CACNG8 PIP4K2B PIP4K2C PIP5K1A CACNA2D3 CACNB1 WIPF1 CACNG3 CYFIP1 CAPN1
PIP4K2A CAPN7 CACNG2 CACNG4 CACNA2D4 DES PIP5K1B PIP5K1C MSN STMN1 CACNA1C ABL2
PPH2 ABL1 HIST1H3J SPNS1 PIAS2 OA2 PPIG HIST1H3B HIST1H3A HIST1H3I HIST1H3E HIST1H3H
HIST1H3G HIST1H3F HIST3H3 PPP1R3A PPP1R15A PPP1R9B ATM ATR TUBA4A TUBG1 TUBB4A TUBB2A
TUBD1 PIGU PPP1R11 PIK3CG PPP1R12C PPP1R16A PPP1R9A PIK3C2G PPP1R3D PPP1R1B FYN HIST1H3C
CDC42EP5 BAIAP2 NCF2 CDC42EP3 TNFRSF25 CDC42EP4 CDC42EP1 CDC42EP2 ROCK1 ROCK2 PLD1 ACTR3
ACTR2 PKN1 SRF MAP3K9 IQGAP1 ETS1 ETS2 ARFIP2 BRF1 PAX6 ZFP36L1 LAT
TP53BP2 HAT1 ZBTB17 ESR2 ARHGDIB DUSP1 DUSP12 DUSP3 ESR1 RDX ARHGDIA SLC9A1
PPP1R3C BCL2L1 CDK4 CDKN2D CDK6 CDKN2C CDKN2B CD40 CTNNA3 CTNND1 XCR1 CDKN1B
CDKN2A CDK1 CDC25C CD4 CD27 CD28 CDK2 CDKN1A CDC25A CTNNA2 CTNNA1 TMSB4Y
TMSB4X TGFB1I1 FERMT2 POTEF JUNB JUND CLEC18C DCHS1 PTGS2 PPP2R5D AXIN1 HRH4
TESK1 RSU1 VEGFA FBLIM1 MFSD7 CDC25B MDM2 RALGDS RASGRF2 RASA1 RAD51 RAP2A
RHEBP1 FPR2 NCSTN RHEB RALBP1 RASGRP1 RARG RAP2B RALB RARA RALA RAPGEF1
RAP2C RARB BAK1 IHH NOTCH3 NOTCH4 NOTCH2 NOTCH1 RB1 NPTN RBL1 RBPJ
TAB1 TAB2 NFKBIB NF1 NFKBIE NLK NLRP2 GAB2 GAB1 GLI1 NACA FLNC
FOSB FOSL1 DOCK1 IRS2 FOSL2 ACTG2 ACTA2 ACTN1 ACTN3 IRS4 LIMS2 MYO1C
MYH6 MYL6 MYH15 MYL7 LIMS1 MUC1 MYO1G ACTN4 ACTB NOS2 KRT18 NCK2
CDH26 CDH24 CDH22 CDH23 CDH20 RHOQ RHOJ ACTA1 ACTN2 ACTG1 ILK SNAI2
RA5 PCDHGB4 SNAI1 MYO10 MYO6 MYL4 MYO1E MYH7B MYH4 MYH13 MYH7 MYH3
MYL1 MYH14 MYO3B PARVA FLNB FLNA PARVB DSP MYO1F RNASEH2A DSPP MYO18B
MYL5 MYH1 MYO9A MYH10 MYL12A MYO3A MYH11 MYL2 MYO1A MYH2 MYO9B MYO1D
MYL3 MYO5A MYO7A MYO15A MYH9 MYH8 MYO1B RASGRP2 RASGRF1 CBL FANCD2 FADD
FAS TSC2 TSC1 PRKAG3 PRKAG1 PRKAB1 CHEK1 CHEK2 EP300 E2F1 E2F3 MMAB
JAK3 ADAM17 JAK1 JAK2 PRKDC PRKAA2 FZD9 FZD6 FZD4 FZD1 CXCR5 CXCR1
CX3CR1 CXCR3 FZD5 FZD7 PRKAG2 PRKAB2 PRKAA1 DIABLO FZD8 FZD2 FZD3 FZD10
E2F5 E2F4 APC APH1A APH1B APAF1 TGFBR2 SERPINA2 SOX17 FEOM3 SUFU PTCH1
PTCH2 TNFRSF18 TNFRSF10D TNFRSF14 TNFRSF17 DVL1P1 OSMR HIPK2 DVL1 SOX14 SOX5 SOX6
SOX10 SOX12 SOX8 SOX18 E2F2 BRCA1 SOX9 SOX15 SOX21 SOX30 SOX13 SOX1
SOX3 SOX7 SOX2 SOX11 SOX4 CXCR6 CXCR4 BMPR1A IL10RA IL6R IL20RA BMPR1B
BMPR2 RPTOR BBC3 SYNGAP1 IL13RA1 IL18R1 IL7R IL4R IL9R IL17RA IL2RG IL3RA
IL12RB1 IL11RA CNOT6 VHL WEE1 CASP6 CAMK2G CREBBP CRK BID BIRC2 BIRC3
CASP7 CASP10 CSF3R CSF2RB BCL2L11 CSF2RA CASP8 CAMK2D CAMK2A CAMK2B IL10RB IL2RB
CCNE1 FOXO1 WNT5A CCRL2 CCR2 CCR7 CCND3 CCNE2 WNT1 STK11 ANTXR1 REPS1
CXCR2 DHH PSEN1 STK36 PSEN2 PSENEN CCR5 CCR3 IL22RA1 IL12RB2 ACVR2B IL5RA
IL23R IL13RA2 IL17RC IL15RA ACVR1 ACVRL1 CCND2 CCR6 CCR10 CCR4 CCR8 ACKR2
CCR1 CCR9 TNFAIP6   
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network for ERK Signaling SuperPath

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