ERK Signaling SuperPath

Pathway network for ERK Signaling SuperPath
1178 Genes in the ERK Signaling SuperPath
ACAN ALK ANGPTL6 AREG AXL BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5
BMP6 BMP7 BMP8A BTC COL18A1 COL19A1 COL1A1 COL1A2 COL22A1 COL23A1 COL24A1 COL25A1
COL27A1 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A3 COL8A1 COL9A1
VCAN NCAN SMC3 DDR1 DDR2 EPYC TYMP ECM1 ECM2 EGF EGFR ELN
EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6
EPOR ERBB3 ERBB4 FBN2 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17
FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8
FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 FN1 FOS GAS6 GAS8 GDF2
GDF5 GNRH1 GNRH2 GPC6 HAPLN4 HSPG2 IGF1 IGF1R IGF2 IGF2-AS IL2 IL3
IL6 IL9 IMPG1 IMPG2 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2
ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 JUN KDR COL20A1 KIT KITLG LAMA1
LAMA2 LAMA3 LAMA5 LAMB2 LAMC2 LEFTY1 LHB LIFR LMTK2 LMTK3 LTBP1 LTBP2
LTBP3 LTBP4 MAPK1 MAPK3 MEPE MERTK MET MST1R NFKB1 NGF NRG1 NRG2
NRG3 NTF3 NTRK1 NTRK2 NUDT6 OGN PIK3R5 PDGFA PDGFB PDGFC PDGFRA PDGFRB
PIK3R1 PIK3R2 PIK3R3 PIK3R4 GDF15 PLPP3 PPBP PRG2 PRG4 PROK1 PSIP1 PTN
RAC1 ROR1 ROR2 ROS1 RYK PDGFD CLEC11A SPOCK1 SPOCK2 SPOCK3 SPON1 SPON2
SPP1 TBRG1 TEK TGFA TGFB1 TGFB2 TGFB3 THPO TIE1 KLF10 TIMP1 TIMP2
TIMP3 TIMP4 TNF TYRO3 VEGFB VEGFC UTS2 TNC TDGF1 SEMA5A SEMA4G SEMA4B
SEMA3A PTK7 PTK2B PTK2 PGF PENK NTRK3 NTF4 MUSK MMRN2 MDK LAMC3
LAMC1 LAMB4 LAMB3 LAMB1 LAMA4 INSRR INSR HGF HDGF HAPLN3 HAPLN2 GMFG
GHRH GH2 GH1 GFER GDF9 GDF6 GDF10 GAS2 GAS1 FRAS1 VEGFD FBN3
FBN1 ERBB2 EFEMP2 EFEMP1 LEFTY2 CXCL12 CTGF CSF1R HAPLN1 COL9A3 COL9A2 COL8A2
COL7A1 COL6A3 COL6A2 COL6A1 COL5A2 COL5A1 COL21A1 COL17A1 COL16A1 COL15A1 COL14A1 COL13A1
COL12A1 COL11A2 COL11A1 COL10A1 CDC42 MAPK10 MAPK8 MAPK9 MYC BCL2 ELK1 GNA11
GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAT1 GNAT2
GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3
GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 IL1A IL1B ITGA1 ITGA10 ITGA11 ITGA2
ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 LTA MAP2K1 MAP2K2 OSM
PAK1 RAF1 RHOA RHOB RHOC RHOD RHOG RHOH DIRAS3 ATF1 BAD CDH1
CREB1 CREB3 CREB3L4 RAC2 RAC3 TNFRSF1A ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6
ADCY7 ADCY8 ADCY9 ANGPT1 ANGPT2 ANGPT4 ANGPTL1 TCF4 TCF3 RPS6KA5 RPS6KA4 CHUK
ATF4 RND2 ARHGEF6 RND3 BAX BMP15 BMP8B BRAF BTK CCL1 CCL11 CCL13
CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL2 CCL20 CCL21 CCL22 CCL23 CCL24
CCL25 CCL26 CCL27 CCL28 CCL3 CCL3L1 CCL4 CCL4L1 CCL4L2 CCL5 CCL7 CCL8
CD2 CD80 CER1 CSF1 CSF2 CSF3 CX3CL1 CXCL1 CXCL10 CXCL11 CXCL13 CXCL14
CXCL16 CXCL2 CXCL3 CXCL5 CXCL6 CXCL9 DAP GRB2 HRAS IL10 IL11 IL12A
IL12B IL13 IL15 IL16 IL17A IL18 IL19 IL20 IL21 IL22 IL23A IL24
IL26 IL4 IL5 IL7 CXCL8 KRAS LIF MAP2K3 MAP2K6 MAP2K7 MRAS NRAS
PF4 PF4V1 PIP PLCB1 PLCB2 PLCB3 PLCB4 PPBPP2 PRKACA PRKACB PRKACG PRKAR1A
PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKD1 PRKD3 PRKCQ
RAP1A RAP1B RRAS RRAS2 SOS1 SOS2 SRC TNFSF10 TNFSF11 TNFSF12 TNFSF13 TNFSF13B
TNFSF14 TNFSF18 TNFSF4 CD40LG FASLG CD70 TNFSF8 TNFSF9 TP53 PAK2 PAK3 PAK4
PAK6 PAK5 PRKCI PRKCZ AKT1 AKT2 AKT3 ATF2 ATF3 ATF5 ATF6 ATF7
BCAR1 CASP3 CASP9 CCND1 CDH10 CDH11 CDH12 CDH13 CDH15 CDH16 CDH17 CDH18
CDH19 CDH2 CDH3 CDH4 CDH5 CDH6 CDH7 CDH8 CDH9 CEBPB CTNNB1 GSK3B
HIF1A IRS1 LEF1 MAPK6 MYL9 NFE2L1 PDPK1 PPP1R14B PPP2CA PPP2CB PPP2R1A PPP2R1B
PPP2R2A PPP2R2B PPP2R2C PPP2R3A PTPA PPP2R5A PPP2R5B PPP2R5C PPP2R5E PPP2R3B PTEN PXN
HNF1A TCF19 HNF1B TCF20 TCF21 TCF23 TEAD1 TEAD4 TFAM VIM ZNF354A ZEB1
TCF7L2 TCF7 TCF15 TCF12 HNF4A GSK3A MTOR CFL2 CFL1 GCFC2 ARHGEF1 ARHGEF10
ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF2 ARHGEF3 ARHGEF4 ARHGEF5 ARHGEF7 ARHGEF9 ELK3 ELK4
IL1R1 IL2RA MAP3K5 MAP3K7 MAPK11 MAPK12 MAPK13 MAPK14 MAPK7 MAX MCF2L NET1
NFKBIA NGFR TGFBR1 TNFRSF1B TRADD TUBB2A ARAF CNKSR1 LAMTOR3 MKNK1 MKNK2 MYLK
PLCG1 PPP1R12A PPP1R12B RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA6 STAT1 STAT3 MAP2K4 MAP2K5 MAP3K10
MAP3K11 RHOJ RHOQ CDH20 CDH22 CDH23 CDH24 CDH26 DOCK1 DSP FBLIM1 FLNA
FLNB FLNC FOSB FOSL1 FOSL2 ILK IRS2 IRS4 JUNB JUND MYH15 KRT18
LIMS1 LIMS2 CLEC18C MYH10 MYH14 MYL1 MYL2 MYL3 MYL4 MYL5 MYL6 MYL7
MYO10 MYO15A MYO18B MYO1A MYO1B MYO1C MYO1E MYO1F MYO1G MYO3A MYO3B MYO5A
MYO6 MYO7A MYO9A MYO9B NACA NCK2 NOS2 PARVA PARVB DCHS1 FERMT2 PPP2R5D
TESK1 TGFB1I1 TMSB4X TMSB4Y VEGFA ABL1 ABL2 ACVR1 ACVR2B ACVRL1 ADAM17 APAF1
APC SNAI2 SNAI1 RSU1 PTGS2 MYO1D MYH9 MYH8 MYH7B MYH7 MYH6 MYH4
MYH3 MYH2 MYH13 MYH11 MYH1 MUC1 MYLPF ACTN4 ACTN3 ACTN2 ACTN1 ACTG2
ACTG1 ACTB ACTA2 ACTA1 APH1A ATM ATR AURKB AURKC AXIN1 BAK1 BBC3
BCL2L1 BCL2L11 BID BIRC2 BIRC3 CXCR5 BMPR1A BMPR1B BMPR2 BRCA1 CAMK2A CAMK2B
CAMK2D CAMK2G CASP10 CASP6 CASP7 CASP8 CBL CCND2 CCND3 CCNE1 CCNE2 CCR1
CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCRL2 CD28 CD4 CDK1
CDC25A CDC25B CDC25C CDK2 CDK4 CDK6 CDKN1A CDKN1B CDKN2A CDKN2B CDKN2C CDKN2D
CFLAR CHEK1 CHEK2 CREBBP CRK CSF2RA CSF2RB CSF3R CTNNA1 CTNNA2 CTNNA3 CTNND1
CX3CR1 CXCR3 CXCR4 CXCR6 CYCS DHH DVL1 E2F1 E2F2 E2F3 E2F4 E2F5
EP300 FADD FANCD2 FOXO1 FPR2 FYN FZD1 FZD10 FZD2 FZD3 FZD4 FZD5
FZD6 FZD7 FZD8 FZD9 GAB1 GAB2 GLI1 GNB1L RACK1 CCR10 HAT1 HIPK2
HRH4 IHH IL10RA IL10RB IL11RA IL12RB1 IL12RB2 IL13RA1 IL13RA2 IL15RA IL17RA IL17RC
IL18R1 IL20RA IL22RA1 IL23R IL2RB IL2RG IL3RA IL4R IL5RA IL6R IL7R CXCR1
CXCR2 IL9R JAK1 JAK2 JAK3 LRP5 LRP6 SMAD1 SMAD2 SMAD4 SMAD5 SMAD9
TAB1 TAB2 MDM2 SMAD3 NBN NCSTN NF1 NFKBIB NFKBIE NLK NOTCH1 NOTCH2
NOTCH3 NOTCH4 NUMB OSMR PSENEN PIK3C2G PIK3CG PMAIP1 PRKAA1 PRKAA2 PRKAB1 PRKAB2
PRKAG1 PRKAG2 PRKAG3 PRKDC PSEN1 PSEN2 APH1B PTCH1 PTCH2 RAD51 RALA RALB
RALBP1 RALGDS RAP2A RAP2B RAP2C RAPGEF1 RPTOR RARA RARB RARG RASA1 RASGRF1
RASGRF2 RASGRP1 RASGRP2 RB1 RBL1 RBPJ RHEB NPTN DIABLO SMO SOX1 SOX10
SOX11 SOX12 SOX13 SOX14 SOX15 SOX17 SOX18 SOX2 SOX21 SOX3 SOX30 SOX4
SOX5 SOX6 SOX7 SOX8 SOX9 STK11 STK36 AURKA SUFU SYNGAP1 TGFBR2 TNFAIP6
TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF11A TNFRSF25 TNFRSF12A TNFRSF13B TNFRSF13C TNFRSF14 TNFRSF17 TNFRSF18
TNFRSF21 TNFRSF4 CD40 FAS TNFRSF6B CD27 TNFRSF8 TNFRSF9 TSC1 TSC2 TUBA4A TUBA3C
TUBA8 TUBB1 TUBB3 TUBB7P TUBD1 TUBE1 TUBG1 TUBG2 VHL WEE1 WNT1 WNT5A
XCR1 BRF1 CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S
CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4
CACNG5 CACNG6 CACNG7 CACNG8 CAPN1 CAPN10 CAPN11 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7
CAPN9 CAPNS1 CD3D CD3E CD3G CD247 DUSP1 DUSP3 ESR1 ESR2 ETS1 ETS2
H3F3A H3F3B HIST1H3A HIST1H3B HIST1H3C HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J
HIST3H3 HMGN1 LAT PAX6 PPP1R10 PPP1R11 PPP1R12C PPP1R13B PPP1R14A PPP1R15A PPP1R16A PPP1R1A
PPP1R1B PPP1R2 PPP1R3A PPP1R3B PPP1R3C PPP1R3D PPP1R3F PPP1R7 PPP1R8 PPP1R9A PPP1R9B SRF
TP53BP2 UBTF ZAP70 PCDH9-AS3 PCYT1B-AS1 ACTR2 ACTR3 ARFIP2 ARHGDIA ARHGDIB BAIAP2 SEPT7
CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 CDC42EP5 CIT CYFIP1 DES DIAPH3 GFAP IQGAP1 LIMK1
LIMK2 MAP3K9 SEPT9 MSN NCF2 SEPT2 PARD3 PARD6A PIP5K1A PIP5K1B PIP5K1C PIP4K2A
PIP4K2B PIP4K2C PLD1 SEPT5 SEPT4 PKN1 RDX ROCK1 ROCK2 CLIP1 SLC9A1 STMN1
EZR WASF1 WASF3 WASL WIPF1 CLEC14A DDIT3 HBEGF GLG1 HSF1 IGF2R IL1R2
IRAK1 IRAK2 IRAK3 IRAK4 MAP3K2 MAP3K3 MAP3K4 MAP3K8 MAPK8IP1 MAPK8IP2 MAPK8IP3 MAPKAPK2
MEF2A MEF2C MEF2D NRP1 NRP2 OGFR PLCD1 PLCD3 PLCD4 PLCE1 PLCG2 PLCZ1
WNK1 RIPK1 SH3RF1 STAT2 STAT4 STAT5A STAT5B STAT6 TGFBR3 TLN1 TLN2 TRAF2
TRAF6 VCL
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network for ERK Signaling SuperPath