ERK Signaling SuperPath

Pathway network for ERK Signaling SuperPath
1067 Genes in the ERK Signaling SuperPath
ITGB6 ITGB5 IL2 ITGAD ITGAV ITGAL ITGAM IL3 GAS8 BMP3 BMP10 BMP8A
BMP1 IL6 IL9 ITGB4 ITGB8 DDR1 GAS6 DDR2 HDGF HAPLN3 HAPLN4 GAS2
GAS1 ITGAX ITGB1 ITGAE ITGB7 ITGB2 ITGB3 BMP2 BMP6 COL5A3 COL19A1 COL4A3
COL5A1 COL18A1 COL6A1 COL4A2 COL21A1 COL4A6 COL1A1 COL6A3 COL16A1 COL4A4 COL10A1 COL13A1
COL8A1 COL15A1 GH2 GH1 GHRH BMP5 BMP7 BMP4 PGF PTK2B COL7A1 COL5A2
COL11A2 PTK2 FGF10 PTK7 HAPLN2 NTF3 LIFR MMRN2 IGF1R IGF2 ECM1 MUSK
ECM2 IGF1 TYRO3 PIK3R2 PIK3R3 PIK3R1 PIK3R4 UTS2 THPO FRAS1 GPC6 VEGFC
VEGFB GNRH1 GNRH2 TNF TNC FBN3 FBN1 INSR INSRR LHB NUDT6 FBN2
GFER PENK FN1 MERTK MET MEPE PSIP1 GDF10 MST1R GDF6 FOS NTRK1
NTRK3 NTRK2 GDF9 GDF5 GDF2 ANGPTL6 ELN PROK1 PRG4 SPP1 SPOCK3 SPOCK2
SPON2 PRG2 SPON1 CXCL12 GMFG PPBP FIGF TEK PPAP2B COL9A2 COL11A1 KDR
LMTK3 FLT1 FLT4 SEMA4B SEMA5A FLT3 LMTK2 EGFR BDNF AXL CTGF EFEMP1
EGF JUN SEMA3A SEMA4G EPHA4 EPHB1 EPHA5 EPHB4 TGFB2 EPHA7 EPHA2 EPHB3
EPHA1 EPHA3 EPHA8 EPHB6 EPHB2 EPOR LTBP4 LTBP2 FGFR1 FGF6 FGF21 FGFR4
FGF19 FGF18 FGF5 FGF14 FGF22 FGF16 FGF11 FGF12 FGF2 FGFR3 FGF17 FGF23
RYK AREG IMPG1 IMPG2 LTBP3 LTBP1 EFEMP2 FGFR2 FGF4 FGF1 FGF8 FGF13
FGF20 FGF7 TDGF1 MDK TIMP2 MAPK3 TIMP1 MAPK1 TIMP3 COL1A2 PTN HGF
TIMP4 ALK ROR2 LAMB4 LAMB2 CSF1R LAMA4 COL17A1 COL3A1 COL12A1 COL27A1 COL4A1
COL25A1 COL4A5 COL23A1 COL22A1 COL8A2 COL9A1 COL6A2 COL14A1 COL9A3 COL24A1 COL2A1 ROR1
ROS1 KIT KITLG LAMA2 TBRG1 RAC1 LAMC3 TGFA TGFB1 OGN TGFB3 ERBB4
ERBB3 NFKB1 ERBB2 LAMB1 NRG3 PDGFA PDGFC PDGFB PDGFRB PDGFRA LAMA3 LAMB3
LAMC1 NRG2 NRG1 LAMA1 LAMC2 LAMA5 BTC HSPG2 LTA GNAT1 GNAI2 GNG11
GNAT2 GNAI3 GNB3 GNAO1 GNG3 GNG4 GNG12 GNAL GNG2 GNG13 GNAZ GNB4
GNAI1 GNG7 GNG10 GNA12 GNG8 GNB1 GNGT2 GNA13 GNA11 GNA14 GNGT1 ITGA2
ITGA11 ITGA5 ITGA2B ITGA7 ITGA8 ITGA1 MAP2K1 MAP2K2 IL1A IL1B ITGA10 ITGA3
GNA15 GNG5 GNB2 GNB5 OSM PAK1 ITGA4 ITGA9 ITGA6 ELK1 RAF1 BCL2
CDC42 MAPK9 MAPK8 MAPK10 MYC CCL14 CCL11 CCL22 CCL27 CCL23 CCL21 CREB1
IL16 IL4 CREB3 CREB3L4 CCL4 CCL13 CCL4L1 CCL1 CCL5 CCL7 CCL2 CCL24
CCL4L2 CCL3 CCL17 CCL15 CCL18 CCL20 CCL16 CCL19 IL5 CCL25 CCL8 CCL28
CCL3L1 CCL26 IL12A RPS6KA5 MAP2K3 MAP2K6 MAP2K7 RPS6KA4 PLCB2 PLCB1 CSF2 CSF3
RAP1B BAX GRB2 RAP1A NRAS CSF1 BTK PLCB4 PLCB3 IL7 IL22 IL15
IL11 IL26 IL21 SRC IL10 IL8 IL20 IL24 BMP15 IL13 IL19 IL12B
IL23A IL18 ANGPT2 TP53 RRAS2 RRAS TNFSF11 TNFSF9 TNFSF18 TNFSF13B TNFSF12 SOS1
SOS2 LIF ADCY3 ADCY5 RAC3 PF4 BRAF PF4V1 TNFSF4 TNFSF10 PAK7 PRKCI
PRKCZ PAK3 PAK2 PAK4 PAK6 DAP MRAS TNFSF8 TNFSF14 TNFSF13 BAD CDH1
PIP ARHGEF6 ADCY8 ADCY7 CXCL3 CXCL13 CXCL2 CXCL16 CX3CL1 CXCL10 CXCL9 CXCL5
CXCL6 ANGPT4 ANGPTL1 CD2 ANGPT1 RAC2 CXCL1 CXCL14 PRKCE PRKAR1B ADCY6 PRKACA
PRKAR2A ADCY2 ADCY1 ADCY9 ADCY4 PRKCA PRKACB PRKCD PRKACG PRKAR1A PRKCQ PRKCG
PRKAR2B PRKCH CER1 CXCL11 TCF4 ATF1 HRAS ATF4 CHUK TCF3 TNFRSF1A CD80
TNFRSF1B AKT1 PPP2R5C PPP2R1B PPP2R2A PPP2R5A PPP2R1A PPP2CB PPP2R5E AKT3 TCF19 TCF7L2
TFAM TCF23 TCF7 TEAD4 AKT2 TCF20 TEAD1 PPP2R4 IL1R1 RPS6KA6 CCND1 IL2RA
CEBPB RPS6KA1 RPS6KA3 STAT3 ARHGEF1 STAT1 PLCG1 RPS6KA2 MAPK6 PPP2R5B GSK3A PPP2R2C
GSK3B PPP2R2B PPP1R14B PPP2CA PDPK1 BCAR1 CASP3 CASP9 HNF4A TCF12 PPP1R12A CDH9
CDH5 CDH11 MCF2L CDH15 CDH18 CDH2 VIM CTNNB1 PXN CDH7 CDH6 TGFBR1
CDH19 CDH13 CDH3 NFE2L1 CDH8 CDH16 CDH12 CDH10 CDH4 CDH17 NGFR NET1
ATF6 ATF5 ATF2 ATF3 ELK3 ELK4 TCF15 ARHGEF7 TCF21 ATF7 IRS1 CFL2
MAP3K10 MYL9 HIF1A PTEN LEF1 MAP3K11 MYLK CFL1 MAP2K4 MAP2K5 PPP1R12B PPP2R3A
ARHGEF10 MAP3K7 MAP3K5 MAPK11 MKNK1 ARHGEF9 ARHGEF12 MAX MAPK12 MAPK13 NFKBIA MKNK2
ZNF354A TRADD MAPK7 MAPK14 ARHGEF4 ARHGEF16 ARHGEF15 ARHGEF2 ARHGEF3 ARHGEF5 ARHGEF11 DSP
DIAPH3 PLCD1 MAPKAPK2 ABL1 STMN1 FYN ABL2 TMSB4Y MSN PLCG2 TUBB2A TUBD1
PARVB TUBB1 TUBB3 TUBE1 TUBG1 ATM PIK3C2G MAP3K8 TMSB4X ATR PLCZ1 PIK3CG
MAPK8IP1 CDC42EP3 CDC42EP5 CDC42EP2 CDC42EP1 MAPK8IP3 BAIAP2 NCF2 MAP3K4 MAP3K9 MAP3K3 ROCK2
ROCK1 MAP3K2 CDC42EP4 HAT1 GAB2 PLD1 ACTR3 ACTR2 GAB1 ARFIP2 SLC9A1 RDX
ARHGDIA ARHGDIB IQGAP1 MAPK8IP2 PLCE1 TLN1 HSF1 GNB1L TLN2 CDH26 TGFBR3 VCL
IRAK2 STAT4 IRAK3 IRAK4 IRAK1 IGF2R KRT18 TNFRSF13B MYO1E MYL4 TNFRSF10A MYH4
MYH7B TNFRSF10C MYH14 DDIT3 TGFB1I1 TNFRSF11A TNFRSF12A GNB2L1 STAT5B NUMB SMO PMAIP1
PARVA PLCD4 CFLAR CYCS AURKC TUBA8 AURKB LRP5 LRP6 PLCD3 IL1R2 STAT2
STAT5A MYO1F STAT6 MYO3B MEF2C CDH24 CDH23 CDH22 MEF2A MEF2D CDH20 TUBG2
FLNC HIST1H3C CACNG2 CACNG4 HIST1H3E CACNG8 CAPN7 CACNA2D4 BRF1 CACNA2D3 LAT TP53BP2
CAPN1 CAPN3 CAPN2 HIST1H3B HIST1H3F HIST1H3D CACNA1G CACNA1H HIST3H3 CACNA1C HIST1H3A HIST1H3I
CACNA1A HIST1H3H HIST1H3G CACNB1 CACNG3 CAPNS1 CACNB4 CACNG1 CAPN10 CACNA1E PAX6 ESR2
ETS2 DUSP3 ETS1 SRF ESR1 CACNA2D2 CAPN5 CAPN11 CACNA2D1 CACNA1D CACNG7 CACNB2
CACNA1F CACNG5 CAPN6 CACNA1S CAPN9 CACNA1I CACNG6 HIST1H3J CACNA1B RIPK1 TRAF6 GFAP
GLG1 CIT TRAF2 PPP1R8 PPP1R3F CYFIP1 PPP1R7 PPP1R1A PPP1R13B JUNB NACA WASF1
NRP1 WASF3 NRP2 LIMK2 WASL FLNB DUSP1 OGFR PARD6A PARD3 FLNA PPP1R2
PIP5K1A PPP1R9A PPP1R12C UBTF PPP1R1B ZAP70 PPP1R16A PPP1R15A H3F3B CACNB3 H3F3A PPP1R3A
HMGN1 PPP1R3D PPP1R11 DES PPP1R3B PIP5K1C PIP5K1B PPP1R14A PPP1R10 PPP1R3C PPP1R9B CD3G
CD3D CD3E LIMK1 SOX15 ACTA1 IL3RA ACTN2 IL18R1 ILK IL20RA IL13RA1 IL12RB1
ACTG1 IL4R IL9R IL7R ACTB IL11RA IL2RG IL6R IL10RA BCL2L1 SNAI1 HRH4
CSF2RB CSF2RA CSF3R BCL2L11 AXIN1 BMPR1B BMPR1A BMPR2 SYNGAP1 VHL BBC3 IL10RB
IL2RB CCR9 DOCK1 CCR1 ACVRL1 ACVR2B ACVR1 CCR8 CCR4 CCR5 CCR7 CCR3
CCR6 CCND2 TESK1 PPP2R5D IL12RB2 ACTN1 IL15RA ACTA2 IL17RC ACTN4 IL13RA2 ACTN3
IL23R IL22RA1 FOSL1 IL5RA FOSB ACTG2 FOSL2 CTNNA1 CTNNA2 NF1 NFKBIE IHH
NFKBIB NLK NOTCH4 NOTCH2 CDK4 BAK1 RALGDS RASGRF2 RAP2A RHEB CDKN2B NCSTN
NOTCH3 NOTCH1 CDKN1A CDC25A CDK2 CDKN2A CDKN2C CDKN1B CD28 CDC25C RBL1 RB1
MDM2 CDC25B CD4 CDKN2D RASA1 SNAI2 CREBBP WEE1 CRK BIRC3 BID BIRC2
CASP6 CAMK2G CAMK2B CASP8 CAMK2A CAMK2D CASP7 CASP10 CTNNA3 CTNND1 RAP2C RARB
RAPGEF1 RASGRP1 RAD51 RALBP1 RALA RARA RASGRP2 RASGRF1 XCR1 RALB RARG RAP2B
CCND3 CCNE2 SOX12 CDK6 SOX21 SOX10 SOX6 SOX18 SOX8 SOX2 SOX11 SOX30
SOX13 SOX3 SOX7 SOX4 MYO1D SOX9 MYO7A MYH9 MYH8 EP300 MYO9B JAK2
JAK3 MYO1B E2F1 MYO15A BRCA1 E2F2 E2F4 E2F3 E2F5 SOX1 SOX5 TNFRSF14
TNFAIP6 TNFRSF10D MYH3 MYH7 TNFRSF18 TNFRSF4 MYL1 TNFRSF21 TNFRSF10B TNFRSF9 TNFRSF8 TNFRSF6B
TNFRSF13C TNFRSF17 MYO18B MYO5A TGFBR2 MYL3 SUFU SOX14 SOX17 MYL5 APC HIPK2
DVL1 OSMR NCK2 APAF1 PTCH2 JAK1 MYH2 JUND MUC1 FZD1 CXCR3 LIMS1
LIMS2 RSU1 FZD9 FZD6 FZD3 FZD10 FZD2 FZD7 FZD4 FZD5 CX3CR1 CXCR6
WNT5A WNT1 FOXO1 CCNE1 CCR2 CCRL2 STK11 STK36 CXCR4 IRS4 IRS2 DHH
PSEN2 PSEN1 FZD8 PRKAG2 CBL FANCD2 TSC2 TSC1 MYO1A MYO3A FADD CHEK1
MYH10 PTGS2 MYO9A MYH1 CHEK2 ADAM17 PRKAB1 PRKAG1 PRKAB2 PRKAA1 MYH6 MYO1C
MYO1G MYL7 PRKAA2 MYL6 MYL2 PRKAG3 MYH11 PRKDC MYO10 MYO6 MYH13           
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network for ERK Signaling SuperPath

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