GPCR Pathway SuperPath

Pathway network for GPCR Pathway SuperPath
745 Genes in the GPCR Pathway SuperPath
TIE1 EPHA2 EPHB3 EPHB2 EPHB1 EPHA4 TEK EPHA5 DDR2 DDR1 EPOR EPHB6
ALK ROR2 ROR1 ROS1 CSF1R RNMT EPHA8 EPHA1 EPHA3 PIK3R3 PIK3R5 FIGF
INSR INSRR IGF1R VEGFB EPHA7 LIFR MUSK VEGFC EPHB4 TYRO3 NTRK2 NTRK1
NTRK3 PIK3R2 PIK3R1 MET PIK3R4 MST1R MERTK PDGFRB PDGFRA FGF18 FGFR4 FGF21
KDR FGF19 FGF17 FGF4 FGF1 FGF23 FGFR1 FGF6 FGF11 FGF22 FGF16 FGF10
FGF12 FGFR3 FGF5 FGF14 FGF2 FGF13 FGF8 LMTK3 ERBB2 ERBB3 FGF7 KIT
LMTK2 FLT3 FLT4 FLT1 EGFR ERBB4 RYK FGFR2 FGF20 AXL PTK7 EGF
SLTM PPAP2B PENK SPON1 HGF TYMP THPO IGF2-AS TBRG1 KLF10 OGN HDGF
GDF9 GDF5 GDF2 GAS8 GAS1 TDGF1 TDGF1P3 MDK GAS6 GAS2 GDF15 GDF6
BTC NRG2 PDGFC PDGFD PDGFA PDF NRG1 NRG3 GRB2 GDF10 KITLG S1PR1
PPBP PDGFB BMP8A UTS2 PROK1 MMDK PGF CLEC11A PTN GNRH2 ANGPTL6 PSIP1
GMFG CXCL12 GNRH1 SOS2 SOS1 TGFA TGFB1 TIMP4 TIMP1 TIMP2 TGFB3 TGFB2
SEMA4B SEMA5A SEMA3A SEMA4G NGF GFER BMP6 BMP7 BMP2 BMP10 BMP3 BMP4
BMP5 IGF2 GH1 GH2 GHRH CTGF BMP1 LHB GPC6 NUDT6 LEFTY2 LEFTY1
NTF4 NTF3 IL9 IL6 IL3 IL2 IGF1 AREG LTBP1 MAPK3 KRAS TIMP3
MAPK1 LTBP2 LTBP3 LTBP4 BDNF-AS BDNF MAPK9 BRAF MAPK8 RRAS2 MAPK12 MRAS
RRAS MAPK10 RAF1 NRAS HRAS CDC42 GNB4 MAPK13 GNG3 ARAF GNB5 GNB1
GNG2 GNB3 AKT1 GNAS FOS GNG4 ARHGEF6 MAPK14 MAPK11 MAP2K2 RNASE1 ARHGEF7
JUN NFKB1 MAP2K1 RAC1 GNB2 MAPK6 PRKACG PRKAR1A PRKACB PRKAR2B PRPF38B MAP2K5
TSPAN1 MAP2K4 GNA15 NET1 PAK1 MAP2K6 MCF2L MAP2K3 PLCB1 GNA14 ELK1 PLCB4
PLCB3 SRC PLCB2 GNA12 GNA13 GNA11 PRKAR2A PRKAR1B PRKACA ARHGEF15 ARHGEF2 ARHGEF3
RHOA RAC3 GNAI3 GNAI1 ARHGEF1 ARHGEF11 ARHGEF5 ARHGEF10 SLC6A2 SLC6A5 ARHGEF16 ARHGEF12
ARHGEF4 ARHGEF9 GNAI2 RAC2 MAPK7 RND2 PAK7 PAK3 PAK2 ITPR2 RND3 RHOC
CHUK RHOG RHOB ITPR1 RHOD PAK6 PAK4 PKN2 CREB3L4 AKT3 ADCY3 ADCY2
CREB3 CREB1 GNAL CALM2 CALM3 CALM1 IKBKB RHOH CCND1 IKBKG ATF4 DIRAS3
PLCG1 P2RY13 ADCY1 PLCG2 GPR119 PLCE1 PRKCQ ITPR3 IKBKE AKT2 E2F4 CCNE2
CCNC CCNB3 CCNB1 CCND3 CCNH CCNE1 E2F3 E2F1 E2F2 TGFBR1 CCNG1 CCNT2
E2F5 CCNA2 CCNT1 CCND2 BP2 CCNB2 ACTG2 POTEF ATF2 MAPK4 ACTA2 ACTB
ITGB3 ITGA6 ITGB2 ACTA1 ACTG1 GNG5 GNGT1 GNG8 GNGT2 GNAZ GNG7 GNG10
GNG13 GNAT2 GNG12 GNAO1 GNAT1 GNG11 ITGB7 ITGAE ITGA8 ITGAD ITGA11 ITGA2
ITGA5 ITGB6 ITGB5 CD247 HBEGF CD3E LCK ITGA1 ITGA2B ITGA7 ITGB8 ITGB4
ITGB1 ITGA9 ITGAX ITGAL ITGAM ITGA10 ITGA3 ITGA4 ITGAV TP53 CDKN1B RAP1A
PRKCH PRKCA CRK ROCK1 PRKCG ROCK2 PTK2 PLCD3 PPP3R1 PPP3CB STAT2 PPP3CA
PPP3CC PLCD4 PTK2B PRKD1 VEGFA STAT5A PRKD3 PRKCE STAT4 STAT5B STAT3 STAT6
STAT1 PRKCB MAP2K7 MAP3K2 PXN MAP3K5 PRKCD MAP3K3 MAP3K4 PLCD1 PLCZ1 PPP3R2
NFATC1 CDKN1A CDK2 NFATC3 CCNA1 NFATC2 NFAT5 NFATC4 BCL2 HLA-DQA1 HLA-DRB4 RCAN3
BLNK HLA-DRB1 HLA-DRB5 HLA-DOA HLA-DQB2 HLA-DPA1 HLA-DMA HLA-DQB1 TNPO1 HLA-DRA FCER2 AKAP5
KPNB1 LYN KPNA3 KPNA2 KPNA1 LAT FCGR1A KPNA4 FCGR3B SYK ITK FCER1A
FCER1G FCGR2A CSNK1E PPP2R3B PPP1R13B PPP1R1A PPP2R2C PPP1R8 PPP2CA CD86 CD80 EGID-102800317
PPP2R5B PPP1R12B PPP1R7 PPP1R14A PPP1R3B PPP1R10 PPP2R2A PPP2R4 PPP1R14B PPP1R3F PPP1R2 PPP2R2B
CD79A CD28 CSNK1A1 CSNK1G1 CABIN1 BTK HLA-DQA2 CSNK1G2 RCAN2 LCP2 CSNK1D CSNK1G3
GSK3A GSK3B CD3G CD4 CD79B CD3D ZAP70 TARP XPO1 IPO5 GATA4 RCAN1
TAF2 CHERP ANCR PSG1 SRA1 EP300 ESR1 BRCA1 NANOS3 ESR2 MED1 CREBBP
NCOA1 NCOA2 NCOR2 SIN3B SIN3A NRIP1 NR0B1 TBP POLR2A POLR1A HDAC6 HDAC10
HDAC7 HDAC11 HDAC5 HDAC2 DDX17 HDAC1 HDAC8 HDAC9 HDAC3 SCAF1 POLR2B POLR2C
PELP1 MGC16025 PPARGC1A DAND5 SP1 NCOA3 NCOR1 GTF2E1 GTF2H4 GTF2E2 GTF2F1 GTF2F2
GTF2H5 PPP1R3C NOS3 GTF2A1 GTF2H3 GTF2H1 SPNS1 HLA-DMB HLA-DOB FYN PHB2 GTF2B
GTF2H2 GTF2A2 TAF11 TAF6L TAF13 TAF9 TAF1A TAF7 TAF1L UBE3A TAF10 TAF5L
TAF4 TAF1B TAF1 TAF5 TAF9B TAF12 TAF1C TAF7L TAF15 TAF6 HLA-DRB3 TUBB3
PRKCZ PRKCI PLD3 SRF BCL10 RAP1B RAPGEF3 CARD10 PLD2 PLD1 ARHGAP5 CYP2E1
SMAD2 RALGDS RASA1 RALB RALA RALBP1 RAPGEF4 NFKBIE ARF3 ARF1 ARF4 NCK1
NCK2 BCAR1 CSK RAPGEF1 ARFGAP1 ARF1P1 NFKBIA PRKCSH REPS1 GPLD1 ARFIP2 ARF6
ARFGAP3 ARF5 SMAD4 SMAD3 JAK1 CDKN2B CDK4 JAK2 JAK3 MMP21 MMP1 MMP26
CDKN2D CDKN2C NOTCH1 BIRC5 BCL2L1 CCNF RB1 FGF9 CDKN2A MDM2 MMP19 MMP8
MMP13 MMP23A MMP23B MMP27 BRCA2 HSP90AA1 PTGS2 TGFBR2 MMP7 MMP9 MMP11 MMP10
MMP20 MMP3 MMP2 MMP12 MMP28 DOCK1 VCL TUBA8 IGF2R NGFR TUBB4B TUBB7P
TUBB1 TUBA3D TUBB FGF3 P2RY11 MYC TP53BP2 TGFBR3 P2RY12 P2RY1 P2RY4 P2RY6
P2RY2 TUBA3C TUBB4A PPP1R11 PPP1R3D PPP1R1B PPP2R5E PPP2CB PPP2R1B PPP1R9B PPP1R12A PPP1R9A
PPP1R12C PPP1R3A TUBA4A TUBB2A PPP2R1A PPP1R15A PPP2R5C PPP1R16A PPP2R3A FEOM3 CLEC14A NRP1
GRB10 GRB7 NRP2 CAMK1G CAMK2D CAMK2G CAMK4 GRB14 OGFR TLN1 PTPN12 PARVA
TLN2 TRPC5 GLG1 RB1CC1 CDK1 CAMK1 CAMK2A ADCY5 ADCY8 ADCY7 UHMK1 NELL1
LIMK2 LIMK1 NELL2 ADCY9 ADCY4 IL2RA NFKBIB CAMK2B STMN1 PRKX ADCY6 TSG101
PPP2R5A
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network for GPCR Pathway SuperPath

Copyright © 2015 , Weizmann Institute of Science. All Rights Reserved.
Version 1.02.021