RET signaling SuperPath

Pathway network for RET signaling SuperPath
974 Genes in the RET signaling SuperPath
RASGRP1 ACTN2 ANGPT1 ARAF ARRB1 ARRB2 BRAF BTC CALM1 CALM2 CALM3 CAMK2A
CAMK2B CAMK2D CAMK2G CSF2 CSF2RA CSF2RB CSK DLG4 HBEGF DUSP1 DUSP2 DUSP4
DUSP5 DUSP6 DUSP7 DUSP8 DUSP9 EGF EGFR ERBB2 ERBB3 ERBB4 EREG FGA
FGB FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGF10 FGFR1
FGFR3 FGFR2 FGFR4 FGG FN1 FYN GDNF GFRA1 GFRA2 GFRA3 GRB2 GRIN1
GRIN2A GRIN2B GRIN2C GRIN2D HGF NRG1 HRAS IL2 IL2RA IL2RB IL2RG IL3
IL3RA IL5 IL5RA IRS1 ITGA2B ITGB3 JAK1 JAK2 JAK3 KIT KRAS MARK3
MET KITLG MAP3K11 NCAM1 NEFL NF1 NRAS NRTN PEBP1 PDGFA PDGFB PDGFRA
PDGFRB PHB PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PPP5C
MAPK1 MAPK3 MAP2K1 MAP2K2 PSPN PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7
PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2
PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9
PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 PTK2 PTPRA RAF1 RAP1A RAP1B RASA1
RASA2 RASGRF1 RASGRF2 RET RPS27A SHC1 SOS1 SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2
SRC TEK TLN1 UBA52 UBB UBC VCL VWF YWHAB SEM1 FGF23 BRAP
RASAL1 CUL3 LAMTOR3 IRS2 PEA15 FGF18 FGF17 FGF16 IQGAP1 SYNGAP1 KSR1 ARTN
KL RASAL2 PSMF1 NRG2 RAPGEF2 PSMD6 FGF19 RBX1 RANBP9 AKAP9 RASA4 PSME3
PSMD14 CNKSR1 NRG3 FRS3 FRS2 DUSP10 RASA3 CNKSR2 PSME4 SHC2 RASGRP3 FGF20
FGF22 LAT LAMTOR2 SPTBN5 SHC3 APBB1IP IL17RD SPTBN4 GFRA4 RASAL3 DUSP16 KBTBD7
WDR83 RASGRP4 PSMB11 PSMA8 NRG4 PAQR3 KLB DAB2IP SPRED1 SPRED2 RASGEF1A KSR2
SPRED3 MIR5004 MIR6852 MIR7703 MIR7855 LOC102724229 PIK3CA PIK3R1 PIK3R2 PIK3CB PTPN11 PDPK1
AKT1 AKT2 MTOR TRIB3 MLST8 THEM4 GAB1 PLCG1 TSC2 AKT1S1 PIK3R3 ITPR1
ITPR2 ITPR3 PIK3CD PRKCA VAV1 PRKCD PRKACA INS INSR PRKACB PRKACG AKT3
AHCYL1 PRR5 MAPKAP1 RICTOR CREB1 CRK LCK FOXO1 FOXO3 MOV10 TNRC6B AGO1
AGO2 TNRC6A TNRC6C AGO3 AGO4 GRK2 PRKCE RAC1 BAD CASP9 CD19 CD28
CD80 CD86 CDKN1A CDKN1B CHUK GSK3A GSK3B NR4A1 MDM2 FOXO4 PIP4K2A PTEN
RPS6KB2 TP53 PIP5K1A PIP5K1B PIP4K2B IER3 PHLPP2 PHLPP1 PIP5K1C ICOS TRAT1 PIP4K2C
PIK3AP1 NGF NTRK1 CRKL RAPGEF1 VAV2 VAV3 ADCY1 ADCY2 ADCY3 ADCY5 ADCY6
ADCY7 ADCY8 ADCY9 CAMK4 PDE1A PDE1C PDE1B PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCG
ADCY4 EIF4B EIF4E EIF4EBP1 EIF4G1 PDE3B PIK3C3 PPM1A PRKAA1 PRKAA2 PRKAB1 PRKAB2
PRKAG1 RHEB RPS6 RPS6KB1 STK11 TSC1 RRAGB LAMTOR5 RRAGA EEF2K PIK3R4 PRKAG2
CAB39 PRKAG3 TLR9 LAMTOR1 STRADB RPTOR RRAGD RRAGC CAB39L STRADA LAMTOR4 LOC101930123
MAPK14 MAPK11 MAPK13 MAPK12 MAPKAPK3 MAPKAPK2 STAT5A STAT5B SYK GAB2 STAT3 KIDINS220
PAK1 PAK2 GRAP2 GRB10 RALA RALB RALGDS RIT2 RIT1 KALRN PTPN6 RHOA
CDC42 NCK1 NCK2 BCAR1 LYN GRB7 LCP2 PLCG2 MAPK7 PRKCQ TRIO RASGRP2
PTK2B INPP5D INPPL1 HSPB1 KDR PAK3 PRKCB PRKCZ PXN VEGFA SPHK1 CBL
TEC IGF1 IGF1R IGF2 IRS4 STAT1 BTK JUN MAPK8 RPS6KA1 RPS6KA2 RPS6KA3
SH3GL2 RPS6KA5 ADRA1D ADRA1B ADRA1A AGT AGTR1 ANXA1 APP AVP AVPR1A AVPR1B
BDKRB1 BDKRB2 BRS3 DAGLA CASR CCK CCKAR CCKBR CHRM1 CHRM3 CHRM5 LTB4R
DGKA DGKB DGKG DGKQ LPAR1 EDN1 EDN2 EDN3 EDNRA EDNRB F2 F2R
F2RL1 F2RL2 FPR2 GAST GCG GCGR GHSR GNA11 GNA15 GNAQ GNB1 GNB2
GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GNRH1 GNRH2 GNRHR
GPR4 XCR1 UTS2R GPR17 LPAR4 MCHR1 MLNR FFAR1 FFAR3 FFAR2 GRK5 GRM1
GRM5 GRP GRPR HCRT HCRTR1 HCRTR2 HRH1 HTR2A HTR2B HTR2C KISS1 KNG1
MLN NMB NMBR NTS NTSR1 OXT OXTR P2RY1 P2RY2 P2RY6 P2RY11 PLCB2
PLCB3 PLCB4 PMCH PRKCH PTAFR PTGER1 PTGFR RGS2 RGS3 SAA1 CCL23 XCL1
XCL2 TAC1 TACR2 TAC3 TACR1 TACR3 TBXA2R TRH TRHR TRPC3 TRPC6 GPR68
GPR65 DGKZ DGKE DGKD NPFF F2RL3 DGKI LPAR2 GNA14 LPAR6 RGS19 NMUR1
GNB5 CYSLTR1 NMU NPFFR2 PROKR1 UTS2 MGLL PLCB1 LPAR3 NTSR2 ABHD12 P2RY10
GPR132 GHRL GNG13 GNG2 GNG12 LTB4R2 NMUR2 CYSLTR2 TRPC7 LPAR5 ABHD6 GNB4
PROK2 NPFFR1 RGS18 QRFPR PROK1 MCHR2 KISS1R OPN4 GNG8 GNRHR2 ARHGEF25 PROKR2
NMS DGKK DGKH DAGLB GPRC6A UTS2B QRFP RGSL1 NPSR1 RGS21 NPS AXL
CAV1 CDH5 CTNNA1 CTNNB1 CTNND1 CYBA CYBB DOCK1 NCKAP1L HSP90AA1 ITGAV JUP
NCF2 NCF4 NOS3 ROCK1 SHB WASF1 SH2D2A ROCK2 ELMO1 ABI1 ABI2 WASF2
BAIAP2 NCKAP1 WASF3 CYFIP1 CYFIP2 BRK1 ELMO2 NCF1 YES1 FOS IGHE IGLC1
IGLC6 IKBKB MAP3K1 NFKB1 NFKBIA MAPK9 MAPK10 MAP2K7 RELA MAP2K4 TRAF6 IGKV3D-11
IGKV5-2 IGKV4-1 ADCYAP1 ADCYAP1R1 ADORA2A AP2A1 AP2A2 AP2B1 ATF1 AP2M1 AP2S1 CLTA
CLTC DNM1 DNM2 DUSP3 ELK1 MEF2A MEF2C NTRK2 MAP2K5 DNAL4 DNM3 VRK3
STAT6 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL6A1 COL6A2 COL6A3 COL9A1 COL9A2 COL9A3
COL6A6 COL6A5 PTPN12 ADAM17 ARHGEF7 CDK1 IL6 IL6R IL6ST TYK2 B2M HLA-E
KLRC2 KLRD1 TYROBP KLRK1 TREM2 KLRC4-KLRK1 FURIN LGALS9 HAVCR2 HCK YWHAZ BLNK
CHEK1 CMA1 FER FES MMP9 SOCS1 SOCS6 SH2B3 PTPRU SH2B2 GRAP GRAPL
CDC34 FCER1A MS4A2 FCER1G ITK NFATC1 NFATC2 NFATC3 PPP3CA PPP3CB PPP3R1 SKP1
MAP3K7 TXK UBE2D1 UBE2D2 UBE2N UBE2V1 LAT2 CUL1 IKBKG BCL10 BTRC TAB1
MALT1 TAB2 FBXW11 CARD11 TAB3 MMP3 ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V0C ATP6V1C1 ATP6V1E1
ATP6V0B ATP6V1G2 ATP6V0A1 ATP6AP1 ATP6V0E1 ATP6V0D1 ATP6V1F ATP6V1G1 TCIRG1 ATP6V0A2 ATP6V0A4 ATP6V1D
ATP6V1H ATP6V1E2 ATP6V1G3 ATP6V0E2 ATP6V0D2 ATP6V1C2 MIR5010 LEP LEPR SOCS3 SH2B1 DOK1
RAP1GAP DOK2 PDLIM7 DOK4 DOK5 SHANK3 DOK6 CACNA1C CACNA1D CACNA1S CACNB1 CACNB2
CACNB3 CACNB4 NCAN PRNP CNTN2 ST8SIA4 ST8SIA2 CACNA1I CACNA1H CACNA1G AGRN ADAM10
EPS15 PTPN3 PTPRK SH3GL1 SH3GL3 STAM ADAM12 HGS SPRY1 SPRY2 STAM2 LRIG1
EPN1 SH3KBP1 PAG1 EPS15L1 CCND3 SEPT7 ETV4 DNAJB1 MYC MAPK4 MAPK6 RAG1
RAG2 XPO1 NCOA3 MAPKAPK5 CDC14B CDC14A CDC42EP2 CDC42EP3 IGF2BP1 CDC42EP5 PLAT PLG
SPP1 THBS1 THBS2 THBS3 THBS4 PDGFC PDGFD CILP ABR ARHGDIA CASP2 CASP3
ECT2 FGD1 HDAC1 HDAC2 IRAK1 MAG MCF2 MYD88 NGFR OMG PCSK6 PCSK5
PRKCI PSEN2 ITSN1 SMPD2 SOS2 TIAM1 YWHAE ARHGEF5 RIPK2 HDAC3 SQSTM1 ARHGEF1
ARHGEF2 ARHGEF6 MAGED1 ARHGEF10 ARHGEF11 ARHGEF17 BCL2L11 NET1 GNA13 PRDM4 AKAP13 ARHGEF15
ARHGEF9 MCF2L ARHGEF12 ARHGEF18 NCSTN ITGB3BP NGEF ARHGEF26 TIAM2 AATF BEX3 ARHGEF16
ARHGEF4 ARHGEF3 APH1A ARHGEF38 ARHGEF10L ARHGEF40 PSENEN RTN4 PLEKHG5 PREX1 PLEKHG2 APH1B
OBSCN LINGO1 ARHGEF39 FGD3 FGD4 ARHGEF19 FGD2 ARHGEF37 ARHGEF35 ARHGEF33 MIR718 LOC100505585
LOC101927057 MIR7706 LOC102725117 VEGFD FLT1 FLT4 PGF VEGFB VEGFC NRP2 NRP1 HLA-B
HLA-C KIR2DS4 KIR2DS5 KIR3DS1 NCR2 SIRPB1 CLEC5A TREM1 CD300LB SIGLEC15 CD300E SIGLEC16
SIGLEC14 KIR2DS2
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network for RET signaling SuperPath