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wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)
SuperPath
Pathway network
for
wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)
SuperPath
6
Pathways
in the
wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)
SuperPath
RHO GTPases regulate CFTR trafficking
Normal wtCFTR traffic / ER-to-Golgi
wtCFTR and delta508 traffic / Clathrin coated vesicles formation (norm and CF)
Delta508-CFTR traffic / ER-to-Golgi in CF
wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)
Transport Clathrin-coated vesicle cycle
135
Genes
in the
wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)
SuperPath
CFTR
RHOQ
GOPC
ARCN1
COPA
COPB1
SEC13
COPB2
SEC24C
SEC24D
STX6
SEC24B
SEC23B
SEC23A
SEC24A
COPE
COPZ1
COPG1
SEC31A
SEC31B
COPG2
SAR1B
COPZ2
SAR1A
PREB
AP2A1
AP2A2
AP2B1
AP2M1
AP2S1
CLTA
CLTB
CLTC
DAB2
ACTA1
ACTA2
ACTB
ACTC1
ACTG1
ACTG2
BIN1
DNM2
EPS15
HIP1
MYO1B
MYO1F
MYO1C
MYO1D
MYO1E
MYO6
PICALM
HIP1R
SNAP91
EPN1
SH3GLB1
SNX9
MYO1G
MYO1H
MYO5B
RAB4A
RAB5A
SNAP25
VAMP2
RAB7A
VAMP8
RAB11A
RAB9A
STX8
VTI1B
STX12
RAB4B
FLNA
FLNB
PRKACA
PRKACB
PRKACG
PRKAR1A
PRKAR1B
PRKAR2A
PRKAR2B
PRKCE
RAB27A
STX1A
TSG101
UBA52
UBB
UBC
EZR
SNAP23
HGS
NHERF2
NHERF1
STAM2
VPS25
CHMP4B
COMMD1
AP1B1
AP1G1
ARF1
AP1S1
GDI1
GDI2
RAB8A
NSF
PIK3C3
STX5
VAMP7
EEA1
STX7
VAMP4
STX16
AP1S2
AP1G2
AP1M1
RABEP1
GOSR1
GCC2
AP1M2
OPTN
PLIN3
RABEPK
YKT6
VPS45
RAB11FIP2
RAB11FIP5
RABGEF1
PIK3R4
BET1L
RBSN
RAB11FIP1
RILP
PLEKHA8
AP1S3
VTI1A
PIKFYVE
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network
for
wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)
SuperPath