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CASP8 activity is inhibited
SuperPath
Pathway network
for
CASP8 activity is inhibited
SuperPath
10
Pathways
in the
CASP8 activity is inhibited
SuperPath
TRAIL signaling
Regulation by c-FLIP
FasL/ CD95L signaling
Caspase activation via extrinsic apoptotic signalling pathway
Caspase activation via Dependence Receptors in the absence of ligand
FAS (CD95) signaling pathway
CASP8 activity is inhibited
TRAIL signaling pathway
Caspase activation via Death Receptors in the presence of ligand
Dimerization of procaspase-8
57
Genes
in the
CASP8 activity is inhibited
SuperPath
CASP8
FADD
CFLAR
TNFSF10
TNFRSF10B
TNFRSF10A
FAS
FASLG
RIPK1
TRAF2
TRADD
CASP10
CASP3
TNFRSF10D
TMED7-TICAM2
TICAM1
DAPK1
DAPK3
DCC
UNC5B
DAPK2
LY96
APPL1
TICAM2
TLR4
CASP9
UNC5A
CD14
MAGED1
IKBKB
CHUK
PIK3CA
PIK3CB
MAPK8
MAP3K1
IKBKG
SMPD1
PIK3R1
BID
PDPK1
SRC
AKT1
SYK
BTK
MAPK14
EZR
CLTC
BIRC2
MAP2K7
MAP2K6
PTPN13
RFC1
FAIM2
MAPK3
DAP3
MAP2K4
TNFRSF10C
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network
for
CASP8 activity is inhibited
SuperPath