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Chondroitin sulfate/dermatan sulfate metabolism
SuperPath
Pathway network
for
Chondroitin sulfate/dermatan sulfate metabolism
SuperPath
13
Pathways
in the
Chondroitin sulfate/dermatan sulfate metabolism
SuperPath
Dermatan sulfate biosynthesis
CS/DS degradation
Chondroitin sulfate/dermatan sulfate metabolism
Defective CHST14 causes EDS, musculocontractural type
Defective B3GALT6 causes EDSP2 and SEMDJL1
dermatan sulfate biosynthesis (late stages)
Diseases associated with glycosaminoglycan metabolism
Chondroitin sulfate biosynthesis
Defective CHSY1 causes TPBS
Defective B3GAT3 causes JDSSDHD
Defective B4GALT7 causes EDS, progeroid type
A tetrasaccharide linker sequence is required for GAG synthesis
Defective CHST3 causes SEDCJD
64
Genes
in the
Chondroitin sulfate/dermatan sulfate metabolism
SuperPath
CSPG5
VCAN
NCAN
CSPG4
DCN
BGN
BCAN
GPC6
GPC2
GPC4
GPC5
GPC3
GPC1
HSPG2
AGRN
SDC1
SDC2
SDC4
SDC3
CHST14
B4GALT7
B3GALT6
CHSY1
B3GAT3
CHST3
UST
DSE
HEXA
HEXB
CHST15
DSEL
HYAL1
IDS
IDUA
ARSB
HYAL3
B3GAT2
CHST13
B3GAT1
CHSY3
CHST11
CHPF2
CSGALNACT2
CHST12
CSGALNACT1
CHST7
XYLT1
XYLT2
CHPF
CHST9
KERA
ACAN
SLC26A2
EXT1
EXT2
FMOD
B4GALT1
LUM
CHST6
OMD
OGN
PRELP
ST3GAL3
PAPSS2
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network
for
Chondroitin sulfate/dermatan sulfate metabolism
SuperPath