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DDX58/IFIH1-mediated induction of interferon-alpha/beta
SuperPath
Pathway network
for
DDX58/IFIH1-mediated induction of interferon-alpha/beta
SuperPath
8
Pathways
in the
DDX58/IFIH1-mediated induction of interferon-alpha/beta
SuperPath
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
Negative regulators of DDX58/IFIH1 signaling
TRAF6 mediated IRF7 activation
Immune response TLR3 and TLR4 induce TICAM1-specific signaling pathway
DDX58/IFIH1-mediated induction of interferon-alpha/beta
SARS-CoV-2 B.1.1.7 variant antagonises innate immune activation
Novel intracellular components of RIG-I-like receptor pathway
TRAF3-dependent IRF activation pathway
110
Genes
in the
DDX58/IFIH1-mediated induction of interferon-alpha/beta
SuperPath
RIGI
MAVS
IRF3
IFIH1
TRIM25
TBK1
IKBKE
IFNB1
RNF135
TRIM4
TRAF3
TRAF6
IKBKG
RIPK1
IFNA1
IRF7
SIKE1
CHUK
IKBKB
CASP8
CASP10
FADD
CYLD
PIN1
RNF125
OTUD5
NLRX1
ATG12
ATG5
ISG15
TANK
CREBBP
EP300
IFNA2
IFNA4
IFNA5
IFNA6
IFNA7
IFNA8
IFNA10
IFNA13
IFNA14
IFNA16
IFNA17
IFNA21
TRAF2
NFKB1
RELA
UBE2K
PCBP2
HERC5
RNF216
RPS27A
TNFAIP3
UBA52
UBB
UBC
UBA7
UBE2D1
UBE2D2
UBE2D3
ITCH
NLRC5
TAX1BP1
UBE2L6
NFKB2
TKFC
MAP3K1
NFKBIA
NFKBIB
DHX58
CD14
REL
RELB
TLR3
TLR4
BECN1
RIPK3
LY96
TIRAP
TICAM1
TICAM2
AGER
NKIRAS2
NKIRAS1
HMGB1
HSP90AA1
HSP90AB1
APP
S100A12
S100B
SAA1
TOMM70
DDX17
DDX3X
SNW1
IFNE
STING1
IFNG
CXCL8
CXCL10
MAPK9
MAPK10
IFNK
CXCL12
AZI2
MAP3K7
DDX3Y
TRADD
TBKBP1
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network
for
DDX58/IFIH1-mediated induction of interferon-alpha/beta
SuperPath