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Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) SuperPath

Pathway network for Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) SuperPath
14 Pathways in the Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) SuperPath
Aberrant regulation of mitotic cell cycle due to RB1 defects G2 Phase
Cell cycle Cell cycle (generic schema) Cyclin D associated events in G1
Diseases of mitotic cell cycle Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
Defective translocation of RB1 mutants to the nucleus Drug-mediated inhibition of CDK4/CDK6 activity
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects Cell cycle Regulation of G1/S transition (part 2)
PTK6 Regulates Cell Cycle Aberrant regulation of mitotic exit in cancer due to RB1 defects
G1 Phase Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
88 Genes in the Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) SuperPath
CDK2 RB1 CDK4 CCND1 CCNE1 CDK6 E2F1 CCND2 CCND3 E2F3 TFDP1 CDKN1B
E2F2 CCNE2 CDKN1A CDKN1C TFDP2 SKP2 E2F4 RBL1 RBL2 ANAPC10 UBE2C ANAPC16
CDC26 ANAPC15 UBE2S ANAPC2 ANAPC4 FZR1 ANAPC5 ANAPC7 ANAPC11 ANAPC1 UBE2D1 UBE2E1
CDC23 CDC16 CDC27 CCNA2 CCNA1 E2F5 CDK7 MNAT1 PTK6 CCNH CDKN2A CDKN2B
CDKN2C CDKN2D CKS1B ABL1 PPP2R3B JAK2 LYN PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A
RPS27A SKP1 SRC UBA52 UBB UBC CUL1 CCNB1 CDK1 CDC25A CDC25B CDC25C
E2F6 CCNB2 CCNB3 DAXX ATRX AKT1 AKT2 CHUK FOS GSK3B JUN MAPK1
MAPK3 RELA SP1 AKT3
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network for Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) SuperPath