Welcome Guest
Log In
|
Sign Up
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
SuperPath
Pathway network
for
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
SuperPath
14
Pathways
in the
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
SuperPath
Aberrant regulation of mitotic cell cycle due to RB1 defects
G2 Phase
Cell cycle Cell cycle (generic schema)
Cyclin D associated events in G1
Diseases of mitotic cell cycle
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
Defective translocation of RB1 mutants to the nucleus
Drug-mediated inhibition of CDK4/CDK6 activity
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects
Cell cycle Regulation of G1/S transition (part 2)
PTK6 Regulates Cell Cycle
Aberrant regulation of mitotic exit in cancer due to RB1 defects
G1 Phase
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
88
Genes
in the
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
SuperPath
CDK2
RB1
CDK4
CCND1
CCNE1
CDK6
E2F1
CCND2
CCND3
E2F3
TFDP1
CDKN1B
E2F2
CCNE2
CDKN1A
CDKN1C
TFDP2
SKP2
E2F4
RBL1
RBL2
ANAPC10
UBE2C
ANAPC16
CDC26
ANAPC15
UBE2S
ANAPC2
ANAPC4
FZR1
ANAPC5
ANAPC7
ANAPC11
ANAPC1
UBE2D1
UBE2E1
CDC23
CDC16
CDC27
CCNA2
CCNA1
E2F5
CDK7
MNAT1
PTK6
CCNH
CDKN2A
CDKN2B
CDKN2C
CDKN2D
CKS1B
ABL1
PPP2R3B
JAK2
LYN
PPP2CA
PPP2CB
PPP2R1A
PPP2R1B
PPP2R2A
RPS27A
SKP1
SRC
UBA52
UBB
UBC
CUL1
CCNB1
CDK1
CDC25A
CDC25B
CDC25C
E2F6
CCNB2
CCNB3
DAXX
ATRX
AKT1
AKT2
CHUK
FOS
GSK3B
JUN
MAPK1
MAPK3
RELA
SP1
AKT3
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network
for
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
SuperPath