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FLT3 signaling in disease
SuperPath
Pathway network
for
FLT3 signaling in disease
SuperPath
9
Pathways
in the
FLT3 signaling in disease
SuperPath
FLT3 signaling by CBL mutants
FLT3 signaling in disease
FLT3 signaling through SRC family kinases
STAT5 Activation
Signaling by FLT3 ITD and TKD mutants
Signaling by FLT3 fusion proteins
FLT3 Signaling
STAT5 activation downstream of FLT3 ITD mutants
Negative regulation of FLT3
48
Genes
in the
FLT3 signaling in disease
SuperPath
FLT3
FLT3LG
GRB2
STAT5A
STAT5B
GAB2
PTPN11
RPS27A
UBA52
UBB
UBC
CBL
CDKN1A
HRAS
KRAS
NRAS
NOX4
PIK3CA
PIM1
PIK3R1
SOS1
BCL2L1
ETV6
GOLGB1
MYO18A
SPTBN1
ZMYM2
TRIP11
FYN
HCK
LCK
SYK
SH2B3
CSK
ABL2
PTPRJ
SLA
SLA2
SOCS2
SOCS6
AKT3
BCL2L11
CDKN1B
AKT1
AKT2
FOXO3
GRB10
GRAP2
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network
for
FLT3 signaling in disease
SuperPath