Golgi-to-ER retrograde transport

Pathway network for the Golgi-to-ER retrograde transport SuperPath

Sources:

Reactome

Pathways in the Golgi-to-ER retrograde transport SuperPath

#	Name	Source	Genes
1	Golgi-to-ER retrograde transport	Reactome	ACTR10 ACTR1A AGPAT3 ARCN1 ARF1 ARF3 ARF4 ARF5 ARFGAP1 ARFGAP2 ARFGAP3 BICD1 BICD2 BNIP1 CAPZA1 CAPZA2 CAPZA3 CAPZB CENPE COPA COPB1 COPB2 COPE COPG1 COPG2 COPZ1 COPZ2 DCTN1 DCTN2 DCTN3 DCTN4 DCTN5 DCTN6 DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 GALNT1 GALNT2 GBF1 KDELR1 KDELR2 KDELR3 KIF11 KIF12 KIF13B KIF15 KIF16B KIF18A KIF18B KIF19 KIF1A KIF1B KIF1C KIF20A KIF20B KIF21A KIF21B KIF22 KIF23 KIF25 KIF26A KIF26B KIF27 KIF2A KIF2B KIF2C KIF3A KIF3B KIF3C KIF4A KIF4B KIF5A KIF5B KIF6 KIF9 KIFAP3 KIFC1 KIFC2 KLC1 KLC2 KLC3 KLC4 NAPA NAPB NAPG NBAS NSF PAFAH1B1 PAFAH1B2 PAFAH1B3 PLA2G4A PLA2G6 RAB18 RAB1A RAB1B RAB3GAP1 RAB3GAP2 RAB6A RAB6B RACGAP1 RINT1 SEC22B STX18 SURF4 TMED10 TMED2 TMED3 TMED7 TMED9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3D TUBA3E TUBA4A TUBA4B TUBA8 TUBAL3 TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 TUBB8B USE1 ZW10 (see all 134) (see less)
2	Intra-Golgi and retrograde Golgi-to-ER traffic	Reactome	ACTR10 ACTR1A AGPAT3 ALPP ARCN1 ARF1 ARF3 ARF4 ARF5 ARFGAP1 ARFGAP2 ARFGAP3 ARFIP2 ARFRP1 ARL1 BET1L BICD1 BICD2 BNIP1 CAPZA1 CAPZA2 CAPZA3 CAPZB CENPE COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8 COPA COPB1 COPB2 COPE COPG1 COPG2 COPZ1 COPZ2 CUX1 CYTH1 CYTH2 CYTH3 CYTH4 DCTN1 DCTN2 DCTN3 DCTN4 DCTN5 DCTN6 DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 GALNT1 GALNT2 GBF1 GCC1 GCC2 GOLGA1 GOLGA4 GOLGA5 GOLIM4 GOSR1 GOSR2 IGF2R KDELR1 KDELR2 KDELR3 KIF11 KIF12 KIF13B KIF15 KIF16B KIF18A KIF18B KIF19 KIF1A KIF1B KIF1C KIF20A KIF20B KIF21A KIF21B KIF22 KIF23 KIF25 KIF26A KIF26B KIF27 KIF2A KIF2B KIF2C KIF3A KIF3B KIF3C KIF4A KIF4B KIF5A KIF5B KIF6 KIF9 KIFAP3 KIFC1 KIFC2 KLC1 KLC2 KLC3 KLC4 M6PR MAN1A1 MAN1A2 MAN1C1 MAN2A1 MAN2A2 NAA30 NAA35 NAA38 NAPA NAPB NAPG NBAS NSF PAFAH1B1 PAFAH1B2 PAFAH1B3 PLA2G4A PLA2G6 PLIN3 RAB18 RAB1A RAB1B RAB30 RAB33B RAB36 RAB39A RAB3GAP1 RAB3GAP2 RAB41 RAB43 RAB6A RAB6B RAB9A RAB9B RABEPK RACGAP1 RGP1 RHOBTB3 RIC1 RINT1 SCOC SEC22B SNAP29 STX10 STX16 STX18 STX5 STX6 SURF4 SYS1 TGOLN2 TMED10 TMED2 TMED3 TMED7 TMED9 TMF1 TRIP11 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3D TUBA3E TUBA4A TUBA4B TUBA8 TUBAL3 TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 TUBB8B USE1 USP6NL VAMP3 VAMP4 VPS45 VPS51 VPS52 VPS53 VPS54 VTI1A YKT6 ZW10 (see all 203) (see less)
3	Factors involved in megakaryocyte development and platelet production	Reactome	ABL1 ACTB AK3 AKAP1 AKAP10 CABLES1 CABLES2 CAPZA1 CAPZA2 CAPZB CARMIL1 CBX5 CDC42 CDK2 CDK5 CENPE DOCK1 DOCK10 DOCK11 DOCK2 DOCK3 DOCK4 DOCK5 DOCK6 DOCK7 DOCK8 DOCK9 EHD1 EHD2 EHD3 GATA1 GATA2 GATA3 GATA4 GATA5 GATA6 H3-3A H3-3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 HBB HBD HBE1 HBG1 HBG2 HDAC1 HDAC2 HMG20B IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNB1 IRF1 IRF2 ITPK1 JAK2 JMJD1C KDM1A KIF11 KIF12 KIF13B KIF15 KIF16B KIF18A KIF18B KIF19 KIF1A KIF1B KIF1C KIF20A KIF20B KIF21A KIF21B KIF22 KIF23 KIF25 KIF26A KIF26B KIF27 KIF2A KIF2B KIF2C KIF3A KIF3B KIF3C KIF4A KIF4B KIF5A KIF5B KIF6 KIF9 KIFAP3 KIFC1 KIFC2 KLC1 KLC2 KLC3 KLC4 MAFF MAFG MAFK MFN1 MFN2 MICAL1 MYB NFE2 PHF21A PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B RAB5A RAC1 RACGAP1 RAD51B RAD51C RBSN RCOR1 SH2B1 SH2B2 SH2B3 SIN3A TP53 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3D TUBA3E TUBA4A TUBA4B TUBA8 TUBAL3 TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 TUBB8B VPS45 WEE1 ZFPM1 ZFPM2 (see all 170) (see less)
4	MHC class II antigen presentation	Reactome	ACTR10 ACTR1A ACTR1B AP1B1 AP1G1 AP1M1 AP1M2 AP1S1 AP1S2 AP1S3 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARF1 CANX CAPZA1 CAPZA2 CAPZA3 CAPZB CD74 CENPE CLTA CLTC CTSA CTSB CTSC CTSD CTSE CTSF CTSH CTSK CTSL CTSO CTSS CTSV DCTN1 DCTN2 DCTN3 DCTN4 DCTN5 DCTN6 DNM1 DNM2 DNM3 DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 IFI30 KIF11 KIF15 KIF18A KIF20A KIF22 KIF23 KIF26A KIF2A KIF2B KIF2C KIF3A KIF3B KIF3C KIF4A KIF4B KIF5A KIF5B KIFAP3 KLC1 KLC2 KLC3 KLC4 LAG3 LGMN OSBPL1A RAB7A RACGAP1 RILP SAR1B SEC13 SEC23A SEC24A SEC24B SEC24C SEC24D SEC31A SH3GL2 SPTBN2 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3D TUBA3E TUBA4A TUBA4B TUBA8 TUBAL3 TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 TUBB8B (see all 126) (see less)
5	COPI-dependent Golgi-to-ER retrograde traffic	Reactome	ARCN1 ARF1 ARF3 ARF4 ARF5 ARFGAP1 ARFGAP2 ARFGAP3 BNIP1 CENPE COPA COPB1 COPB2 COPE COPG1 COPG2 COPZ1 COPZ2 GBF1 KDELR1 KDELR2 KDELR3 KIF11 KIF12 KIF13B KIF15 KIF16B KIF18A KIF18B KIF19 KIF1A KIF1B KIF1C KIF20A KIF20B KIF21A KIF21B KIF22 KIF23 KIF25 KIF26A KIF26B KIF27 KIF2A KIF2B KIF2C KIF3A KIF3B KIF3C KIF4A KIF4B KIF5A KIF5B KIF6 KIF9 KIFAP3 KIFC1 KIFC2 KLC1 KLC2 KLC3 KLC4 NAPA NAPB NAPG NBAS NSF RAB1A RAB1B RACGAP1 RINT1 SEC22B STX18 SURF4 TMED10 TMED2 TMED3 TMED7 TMED9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3D TUBA3E TUBA4A TUBA4B TUBA8 TUBAL3 TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 TUBB8B USE1 ZW10 (see all 100) (see less)
6	Kinesins	Reactome	CENPE KIF11 KIF12 KIF13B KIF15 KIF16B KIF18A KIF18B KIF19 KIF1A KIF1B KIF1C KIF20A KIF20B KIF21A KIF21B KIF22 KIF23 KIF25 KIF26A KIF26B KIF27 KIF2A KIF2B KIF2C KIF3A KIF3B KIF3C KIF4A KIF4B KIF5A KIF5B KIF6 KIF9 KIFAP3 KIFC1 KIFC2 KLC1 KLC2 KLC3 KLC4 RACGAP1 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3D TUBA3E TUBA4A TUBA4B TUBA8 TUBAL3 TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 TUBB8B (see all 61) (see less)

Gene overlap in member pathways for Golgi-to-ER retrograde transport SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	KIF20A	Kinesin Family Member 20A	Protein Coding	6
2	TUBA1B	Tubulin Alpha 1b	Protein Coding	6
3	TUBB3	Tubulin Beta 3 Class III	Protein Coding	6
4	TUBB4A	Tubulin Beta 4A Class IVa	Protein Coding	6
5	TUBB4B	Tubulin Beta 4B Class IVb	Protein Coding	6
6	CENPE	Centromere Protein E	Protein Coding	6
7	KIF2C	Kinesin Family Member 2C	Protein Coding	6
8	KIF3A	Kinesin Family Member 3A	Protein Coding	6
9	TUBA3E	Tubulin Alpha 3e	Protein Coding	6
10	TUBA3D	Tubulin Alpha 3d	Protein Coding	6
11	KLC3	Kinesin Light Chain 3	Protein Coding	6
12	KIFAP3	Kinesin Associated Protein 3	Protein Coding	6
13	KIF4A	Kinesin Family Member 4A	Protein Coding	6
14	TUBB8B	Tubulin Beta 8B	Protein Coding	6
15	KIF26A	Kinesin Family Member 26A	Protein Coding	6
16	KIF4B	Kinesin Family Member 4B	Protein Coding	6
17	RACGAP1	Rac GTPase Activating Protein 1	Protein Coding	6
18	TUBB8	Tubulin Beta 8 Class VIII	Protein Coding	6
19	TUBB2B	Tubulin Beta 2B Class IIb	Protein Coding	6
20	KIF2A	Kinesin Family Member 2A	Protein Coding	6
21	KIF3C	Kinesin Family Member 3C	Protein Coding	6
22	KIF5A	Kinesin Family Member 5A	Protein Coding	6
23	KIF5B	Kinesin Family Member 5B	Protein Coding	6
24	KLC1	Kinesin Light Chain 1	Protein Coding	6
25	KIF11	Kinesin Family Member 11	Protein Coding	6
26	KIF22	Kinesin Family Member 22	Protein Coding	6
27	TUBA8	Tubulin Alpha 8	Protein Coding	6
28	KIF15	Kinesin Family Member 15	Protein Coding	6
29	KLC2	Kinesin Light Chain 2	Protein Coding	6
30	TUBA4A	Tubulin Alpha 4a	Protein Coding	6
31	TUBA3C	Tubulin Alpha 3c	Protein Coding	6
32	TUBB2A	Tubulin Beta 2A Class IIa	Protein Coding	6
33	TUBA1A	Tubulin Alpha 1a	Protein Coding	6
34	TUBAL3	Tubulin Alpha Like 3	Protein Coding	6
35	TUBA4B	Tubulin Alpha 4b	Protein Coding	6
36	TUBB1	Tubulin Beta 1 Class VI	Protein Coding	6
37	KIF18A	Kinesin Family Member 18A	Protein Coding	6
38	TUBB6	Tubulin Beta 6 Class V	Protein Coding	6
39	KIF2B	Kinesin Family Member 2B	Protein Coding	6
40	TUBA1C	Tubulin Alpha 1c	Protein Coding	6
41	KLC4	Kinesin Light Chain 4	Protein Coding	6
42	KIF3B	Kinesin Family Member 3B	Protein Coding	6
43	KIF23	Kinesin Family Member 23	Protein Coding	6
44	KIF1C	Kinesin Family Member 1C	Protein Coding	5
45	KIF12	Kinesin Family Member 12	Protein Coding	5
46	KIF19	Kinesin Family Member 19	Protein Coding	5
47	KIF18B	Kinesin Family Member 18B	Protein Coding	5
48	KIF6	Kinesin Family Member 6	Protein Coding	5
49	KIF21B	Kinesin Family Member 21B	Protein Coding	5
50	KIF1B	Kinesin Family Member 1B	Protein Coding	5
51	KIF13B	Kinesin Family Member 13B	Protein Coding	5
52	KIFC1	Kinesin Family Member C1	Protein Coding	5
53	KIF25	Kinesin Family Member 25	Protein Coding	5
54	KIF1A	Kinesin Family Member 1A	Protein Coding	5
55	KIF26B	Kinesin Family Member 26B	Protein Coding	5
56	KIF27	Kinesin Family Member 27	Protein Coding	5
57	KIF21A	Kinesin Family Member 21A	Protein Coding	5
58	KIF16B	Kinesin Family Member 16B	Protein Coding	5
59	KIF9	Kinesin Family Member 9	Protein Coding	5
60	KIFC2	Kinesin Family Member C2	Protein Coding	5
61	KIF20B	Kinesin Family Member 20B	Protein Coding	5
62	ARF1	ARF GTPase 1	Protein Coding	4
63	CAPZA1	Capping Actin Protein Of Muscle Z-Line Subunit Alpha 1	Protein Coding	4
64	CAPZA2	Capping Actin Protein Of Muscle Z-Line Subunit Alpha 2	Protein Coding	4
65	CAPZB	Capping Actin Protein Of Muscle Z-Line Subunit Beta	Protein Coding	4
66	ACTR1A	Actin Related Protein 1A	Protein Coding	3
67	DCTN2	Dynactin Subunit 2	Protein Coding	3
68	DCTN6	Dynactin Subunit 6	Protein Coding	3
69	KDELR1	KDEL Endoplasmic Reticulum Protein Retention Receptor 1	Protein Coding	3
70	TMED2	Transmembrane P24 Trafficking Protein 2	Protein Coding	3
71	TMED10	Transmembrane P24 Trafficking Protein 10	Protein Coding	3
72	KDELR2	KDEL Endoplasmic Reticulum Protein Retention Receptor 2	Protein Coding	3
73	KDELR3	KDEL Endoplasmic Reticulum Protein Retention Receptor 3	Protein Coding	3
74	DCTN3	Dynactin Subunit 3	Protein Coding	3
75	COPE	Coat Protein Complex I Subunit Epsilon	Protein Coding	3
76	COPA	Coat Protein Complex I Subunit Alpha	Protein Coding	3
77	COPB1	Coat Protein Complex I Subunit Beta 1	Protein Coding	3
78	DYNLL2	Dynein Light Chain LC8-Type 2	Protein Coding	3
79	DCTN1	Dynactin Subunit 1	Protein Coding	3
80	DYNC1H1	Dynein Cytoplasmic 1 Heavy Chain 1	Protein Coding	3
81	DYNC1I1	Dynein Cytoplasmic 1 Intermediate Chain 1	Protein Coding	3
82	DYNC1I2	Dynein Cytoplasmic 1 Intermediate Chain 2	Protein Coding	3
83	DYNC1LI2	Dynein Cytoplasmic 1 Light Intermediate Chain 2	Protein Coding	3
84	COPZ1	Coat Protein Complex I Subunit Zeta 1	Protein Coding	3
85	COPG1	Coat Protein Complex I Subunit Gamma 1	Protein Coding	3
86	TMED3	Transmembrane P24 Trafficking Protein 3	Protein Coding	3
87	ARFGAP3	ARF GTPase Activating Protein 3	Protein Coding	3
88	COPG2	Coat Protein Complex I Subunit Gamma 2	Protein Coding	3
89	ARCN1	Archain 1 Coat Protein Complex I Subunit Delta	Protein Coding	3
90	ARF3	ARF GTPase 3	Protein Coding	3
91	ARF4	ARF GTPase 4	Protein Coding	3
92	ARF5	ARF GTPase 5	Protein Coding	3
93	NSF	N-Ethylmaleimide Sensitive Factor, Vesicle Fusing ATPase	Protein Coding	3
94	TMED7	Transmembrane P24 Trafficking Protein 7	Protein Coding	3
95	DYNC1LI1	Dynein Cytoplasmic 1 Light Intermediate Chain 1	Protein Coding	3
96	DCTN4	Dynactin Subunit 4	Protein Coding	3
97	COPZ2	Coat Protein Complex I Subunit Zeta 2	Protein Coding	3
98	NBAS	NBAS Subunit Of NRZ Tethering Complex	Protein Coding	3
99	STX18	Syntaxin 18	Protein Coding	3
100	TMED9	Transmembrane P24 Trafficking Protein 9	Protein Coding	3
101	ARFGAP1	ARF GTPase Activating Protein 1	Protein Coding	3
102	USE1	Unconventional SNARE In The ER 1	Protein Coding	3
103	ACTR10	Actin Related Protein 10	Protein Coding	3
104	RAB1A	RAB1A, Member RAS Oncogene Family	Protein Coding	3
105	RINT1	RAD50 Interactor 1	Protein Coding	3
106	NAPB	NSF Attachment Protein Beta	Protein Coding	3
107	BNIP1	BCL2 Interacting Protein 1	Protein Coding	3
108	SURF4	Surfeit 4	Protein Coding	3
109	RAB1B	RAB1B, Member RAS Oncogene Family	Protein Coding	3
110	ARFGAP2	ARF GTPase Activating Protein 2	Protein Coding	3
111	DCTN5	Dynactin Subunit 5	Protein Coding	3
112	DYNLL1	Dynein Light Chain LC8-Type 1	Protein Coding	3
113	GBF1	Golgi Brefeldin A Resistant Guanine Nucleotide Exchange Factor 1	Protein Coding	3
114	NAPG	NSF Attachment Protein Gamma	Protein Coding	3
115	NAPA	NSF Attachment Protein Alpha	Protein Coding	3
116	ZW10	Zw10 Kinetochore Protein	Protein Coding	3
117	COPB2	Coat Protein Complex I Subunit Beta 2	Protein Coding	3
118	CAPZA3	Capping Actin Protein Of Muscle Z-Line Subunit Alpha 3	Protein Coding	3
119	SEC22B	SEC22 Homolog B, Vesicle Trafficking Protein	Protein Coding	3
120	RAB3GAP1	RAB3 GTPase Activating Protein Catalytic Subunit 1	Protein Coding	2
121	RAB18	RAB18, Member RAS Oncogene Family	Protein Coding	2
122	BICD2	BICD Cargo Adaptor 2	Protein Coding	2
123	RAB3GAP2	RAB3 GTPase Activating Non-Catalytic Protein Subunit 2	Protein Coding	2
124	GALNT1	Polypeptide N-Acetylgalactosaminyltransferase 1	Protein Coding	2
125	GALNT2	Polypeptide N-Acetylgalactosaminyltransferase 2	Protein Coding	2
126	PAFAH1B1	Platelet Activating Factor Acetylhydrolase 1b Regulatory Subunit 1	Protein Coding	2
127	PAFAH1B2	Platelet Activating Factor Acetylhydrolase 1b Catalytic Subunit 2	Protein Coding	2
128	PAFAH1B3	Platelet Activating Factor Acetylhydrolase 1b Catalytic Subunit 3	Protein Coding	2
129	RAB6B	RAB6B, Member RAS Oncogene Family	Protein Coding	2
130	PLA2G4A	Phospholipase A2 Group IVA	Protein Coding	2
131	AGPAT3	1-Acylglycerol-3-Phosphate O-Acyltransferase 3	Protein Coding	2
132	RAB6A	RAB6A, Member RAS Oncogene Family	Protein Coding	2
133	BICD1	BICD Cargo Adaptor 1	Protein Coding	2
134	PLA2G6	Phospholipase A2 Group VI	Protein Coding	2
135	VPS45	Vacuolar Protein Sorting 45 Homolog	Protein Coding	2
136	ARFRP1	ARF Related Protein 1	Protein Coding	1
137	PLIN3	Perilipin 3	Protein Coding	1
138	STX6	Syntaxin 6	Protein Coding	1
139	RABEPK	Rab9 Effector Protein With Kelch Motifs	Protein Coding	1
140	COG5	Component Of Oligomeric Golgi Complex 5	Protein Coding	1
141	TGOLN2	Trans-Golgi Network Protein 2	Protein Coding	1
142	YKT6	YKT6 Vesicular SNARE Protein	Protein Coding	1
143	MAN1A2	Mannosidase Alpha Class 1A Member 2	Protein Coding	1
144	NAA30	N-Alpha-Acetyltransferase 30, NatC Catalytic Subunit	Protein Coding	1
145	VTI1A	Vesicle Transport Through Interaction With T-SNAREs 1A	Protein Coding	1
146	CUX1	Cut Like Homeobox 1	Protein Coding	1
147	COG2	Component Of Oligomeric Golgi Complex 2	Protein Coding	1
148	RHOBTB3	Rho Related BTB Domain Containing 3	Protein Coding	1
149	ARFIP2	ARF Interacting Protein 2	Protein Coding	1
150	ALPP	Alkaline Phosphatase, Placental	Protein Coding	1
151	COG4	Component Of Oligomeric Golgi Complex 4	Protein Coding	1
152	CYTH4	Cytohesin 4	Protein Coding	1
153	RAB30	RAB30, Member RAS Oncogene Family	Protein Coding	1
154	GOLIM4	Golgi Integral Membrane Protein 4	Protein Coding	1
155	GOLGA1	Golgin A1	Protein Coding	1
156	GOLGA4	Golgin A4	Protein Coding	1
157	RAB43	RAB43, Member RAS Oncogene Family	Protein Coding	1
158	RAB41	RAB41, Member RAS Oncogene Family	Protein Coding	1
159	IGF2R	Insulin Like Growth Factor 2 Receptor	Protein Coding	1
160	ARL1	ARF Like GTPase 1	Protein Coding	1
161	M6PR	Mannose-6-Phosphate Receptor, Cation Dependent	Protein Coding	1
162	MAN1A1	Mannosidase Alpha Class 1A Member 1	Protein Coding	1
163	MAN2A2	Mannosidase Alpha Class 2A Member 2	Protein Coding	1
164	MAN2A1	Mannosidase Alpha Class 2A Member 1	Protein Coding	1
165	RAB9B	RAB9B, Member RAS Oncogene Family	Protein Coding	1
166	BET1L	Bet1 Golgi Vesicular Membrane Trafficking Protein Like	Protein Coding	1
167	VPS54	VPS54 Subunit Of GARP Complex	Protein Coding	1
168	RAB39A	RAB39A, Member RAS Oncogene Family	Protein Coding	1
169	VPS53	VPS53 Subunit Of GARP Complex	Protein Coding	1
170	MAN1C1	Mannosidase Alpha Class 1C Member 1	Protein Coding	1
171	COG6	Component Of Oligomeric Golgi Complex 6	Protein Coding	1
172	RIC1	RIC1 Partner Of RAB6A GEF Complex	Protein Coding	1
173	NAA35	N-Alpha-Acetyltransferase 35, NatC Auxiliary Subunit	Protein Coding	1
174	SCOC	Short Coiled-Coil Protein	Protein Coding	1
175	VPS52	VPS52 Subunit Of GARP Complex	Protein Coding	1
176	STX5	Syntaxin 5	Protein Coding	1
177	TMF1	TATA Element Modulatory Factor 1	Protein Coding	1
178	VPS51	VPS51 Subunit Of GARP Complex	Protein Coding	1
179	GCC1	GRIP And Coiled-Coil Domain Containing 1	Protein Coding	1
180	RAB33B	RAB33B, Member RAS Oncogene Family	Protein Coding	1
181	COG3	Component Of Oligomeric Golgi Complex 3	Protein Coding	1
182	NAA38	N-Alpha-Acetyltransferase 38, NatC Auxiliary Subunit	Protein Coding	1
183	COG8	Component Of Oligomeric Golgi Complex 8	Protein Coding	1
184	VAMP4	Vesicle Associated Membrane Protein 4	Protein Coding	1
185	STX16	Syntaxin 16	Protein Coding	1
186	STX10	Syntaxin 10	Protein Coding	1
187	SYS1	SYS1 Golgi Trafficking Protein	Protein Coding	1
188	COG7	Component Of Oligomeric Golgi Complex 7	Protein Coding	1
189	CYTH3	Cytohesin 3	Protein Coding	1
190	CYTH2	Cytohesin 2	Protein Coding	1
191	CYTH1	Cytohesin 1	Protein Coding	1
192	TRIP11	Thyroid Hormone Receptor Interactor 11	Protein Coding	1
193	VAMP3	Vesicle Associated Membrane Protein 3	Protein Coding	1
194	SNAP29	Synaptosome Associated Protein 29	Protein Coding	1
195	RAB9A	RAB9A, Member RAS Oncogene Family	Protein Coding	1
196	COG1	Component Of Oligomeric Golgi Complex 1	Protein Coding	1
197	GOSR1	Golgi SNAP Receptor Complex Member 1	Protein Coding	1
198	GOSR2	Golgi SNAP Receptor Complex Member 2	Protein Coding	1
199	RAB36	RAB36, Member RAS Oncogene Family	Protein Coding	1
200	GCC2	GRIP And Coiled-Coil Domain Containing 2	Protein Coding	1
201	USP6NL	USP6 N-Terminal Like	Protein Coding	1
202	RGP1	RGP1 Partner Of RAB6A GEF Complex	Protein Coding	1
203	GOLGA5	Golgin A5	Protein Coding	1
204	SH2B3	SH2B Adaptor Protein 3	Protein Coding	1
205	CDK2	Cyclin Dependent Kinase 2	Protein Coding	1
206	CDK5	Cyclin Dependent Kinase 5	Protein Coding	1
207	HMG20B	High Mobility Group 20B	Protein Coding	1
208	SH2B2	SH2B Adaptor Protein 2	Protein Coding	1
209	EHD1	EH Domain Containing 1	Protein Coding	1
210	AKAP10	A-Kinase Anchoring Protein 10	Protein Coding	1
211	H3C14	H3 Clustered Histone 14	Protein Coding	1
212	DOCK11	Dedicator Of Cytokinesis 11	Protein Coding	1
213	GATA5	GATA Binding Protein 5	Protein Coding	1
214	ZFPM1	Zinc Finger Protein, FOG Family Member 1	Protein Coding	1
215	DOCK1	Dedicator Of Cytokinesis 1	Protein Coding	1
216	DOCK2	Dedicator Of Cytokinesis 2	Protein Coding	1
217	DOCK3	Dedicator Of Cytokinesis 3	Protein Coding	1
218	JMJD1C	Jumonji Domain Containing 1C	Protein Coding	1
219	KDM1A	Lysine Demethylase 1A	Protein Coding	1
220	RCOR1	REST Corepressor 1	Protein Coding	1
221	DOCK9	Dedicator Of Cytokinesis 9	Protein Coding	1
222	ZFPM2	Zinc Finger Protein, FOG Family Member 2	Protein Coding	1
223	CBX5	Chromobox 5	Protein Coding	1
224	MAFF	MAF BZIP Transcription Factor F	Protein Coding	1
225	ABL1	ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase	Protein Coding	1
226	SIN3A	SIN3 Transcription Regulator Family Member A	Protein Coding	1
227	SH2B1	SH2B Adaptor Protein 1	Protein Coding	1
228	GATA1	GATA Binding Protein 1	Protein Coding	1
229	GATA2	GATA Binding Protein 2~Name Same As:- HGNC:18350	Protein Coding	1
230	GATA3	GATA Binding Protein 3	Protein Coding	1
231	GATA4	GATA Binding Protein 4	Protein Coding	1
232	GATA6	GATA Binding Protein 6	Protein Coding	1
233	H3-3A	H3.3 Histone A	Protein Coding	1
234	H3-3B	H3.3 Histone B	Protein Coding	1
235	HBB	Hemoglobin Subunit Beta	Protein Coding	1
236	HBD	Hemoglobin Subunit Delta	Protein Coding	1
237	HBE1	Hemoglobin Subunit Epsilon 1	Protein Coding	1
238	HBG1	Hemoglobin Subunit Gamma 1	Protein Coding	1
239	HBG2	Hemoglobin Subunit Gamma 2	Protein Coding	1
240	HDAC1	Histone Deacetylase 1	Protein Coding	1
241	HDAC2	Histone Deacetylase 2	Protein Coding	1
242	EHD3	EH Domain Containing 3	Protein Coding	1
243	EHD2	EH Domain Containing 2	Protein Coding	1
244	H3C15	H3 Clustered Histone 15	Protein Coding	1
245	IFNA1	Interferon Alpha 1	Protein Coding	1
246	IFNA2	Interferon Alpha 2	Protein Coding	1
247	IFNA4	Interferon Alpha 4	Protein Coding	1
248	IFNA5	Interferon Alpha 5	Protein Coding	1
249	IFNA6	Interferon Alpha 6	Protein Coding	1
250	IFNA7	Interferon Alpha 7	Protein Coding	1
251	IFNA8	Interferon Alpha 8	Protein Coding	1
252	IFNA10	Interferon Alpha 10	Protein Coding	1
253	IFNA13	Interferon Alpha 13	Protein Coding	1
254	IFNA14	Interferon Alpha 14	Protein Coding	1
255	IFNA16	Interferon Alpha 16	Protein Coding	1
256	IFNA17	Interferon Alpha 17	Protein Coding	1
257	IFNA21	Interferon Alpha 21	Protein Coding	1
258	IFNB1	Interferon Beta 1	Protein Coding	1
259	IRF1	Interferon Regulatory Factor 1	Protein Coding	1
260	IRF2	Interferon Regulatory Factor 2	Protein Coding	1
261	ITPK1	Inositol-Tetrakisphosphate 1-Kinase	Protein Coding	1
262	JAK2	Janus Kinase 2	Protein Coding	1
263	MAFG	MAF BZIP Transcription Factor G	Protein Coding	1
264	MYB	MYB Proto-Oncogene, Transcription Factor	Protein Coding	1
265	NFE2	Nuclear Factor, Erythroid 2	Protein Coding	1
266	AK3	Adenylate Kinase 3	Protein Coding	1
267	PHF21A	PHD Finger Protein 21A	Protein Coding	1
268	CARMIL1	Capping Protein Regulator And Myosin 1 Linker 1	Protein Coding	1
269	DOCK10	Dedicator Of Cytokinesis 10	Protein Coding	1
270	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	1
271	MFN1	Mitofusin 1	Protein Coding	1
272	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	1
273	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	1
274	PRKAR1A	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha	Protein Coding	1
275	PRKAR1B	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Beta	Protein Coding	1
276	PRKAR2A	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Alpha	Protein Coding	1
277	PRKAR2B	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Beta	Protein Coding	1
278	DOCK6	Dedicator Of Cytokinesis 6	Protein Coding	1
279	RAB5A	RAB5A, Member RAS Oncogene Family	Protein Coding	1
280	RAC1	Rac Family Small GTPase 1	Protein Coding	1
281	RAD51C	RAD51 Paralog C	Protein Coding	1
282	RAD51B	RAD51 Paralog B	Protein Coding	1
283	ACTB	Actin Beta	Protein Coding	1
284	RBSN	Rabenosyn, RAB Effector	Protein Coding	1
285	MICAL1	Microtubule Associated Monooxygenase, Calponin And LIM Domain Containing 1	Protein Coding	1
286	H3C13	H3 Clustered Histone 13	Protein Coding	1
287	TP53	Tumor Protein P53	Protein Coding	1
288	WEE1	WEE1 G2 Checkpoint Kinase	Protein Coding	1
289	MAFK	MAF BZIP Transcription Factor K	Protein Coding	1
290	DOCK5	Dedicator Of Cytokinesis 5	Protein Coding	1
291	AKAP1	A-Kinase Anchoring Protein 1	Protein Coding	1
292	DOCK8	Dedicator Of Cytokinesis 8	Protein Coding	1
293	CABLES2	Cdk5 And Abl Enzyme Substrate 2	Protein Coding	1
294	H3C1	H3 Clustered Histone 1	Protein Coding	1
295	H3C4	H3 Clustered Histone 4	Protein Coding	1
296	H3C3	H3 Clustered Histone 3	Protein Coding	1
297	H3C6	H3 Clustered Histone 6	Protein Coding	1
298	H3C11	H3 Clustered Histone 11	Protein Coding	1
299	H3C8	H3 Clustered Histone 8	Protein Coding	1
300	H3C12	H3 Clustered Histone 12	Protein Coding	1
301	H3C10	H3 Clustered Histone 10	Protein Coding	1
302	H3C2	H3 Clustered Histone 2	Protein Coding	1
303	DOCK7	Dedicator Of Cytokinesis 7	Protein Coding	1
304	H3C7	H3 Clustered Histone 7	Protein Coding	1
305	CABLES1	Cdk5 And Abl Enzyme Substrate 1	Protein Coding	1
306	DOCK4	Dedicator Of Cytokinesis 4	Protein Coding	1
307	MFN2	Mitofusin 2	Protein Coding	1
308	CDC42	Cell Division Cycle 42	Protein Coding	1
309	AP1M2	Adaptor Related Protein Complex 1 Subunit Mu 2	Protein Coding	1
310	ACTR1B	Actin Related Protein 1B	Protein Coding	1
311	SEC24B	SEC24 Homolog B, COPII Component	Protein Coding	1
312	IFI30	IFI30 Lysosomal Thiol Reductase	Protein Coding	1
313	SEC23A	SEC23 Homolog A, COPII Component	Protein Coding	1
314	CTSC	Cathepsin C	Protein Coding	1
315	SEC24A	SEC24 Homolog A, COPII Component	Protein Coding	1
316	OSBPL1A	Oxysterol Binding Protein Like 1A	Protein Coding	1
317	AP2M1	Adaptor Related Protein Complex 2 Subunit Mu 1	Protein Coding	1
318	AP1S1	Adaptor Related Protein Complex 1 Subunit Sigma 1	Protein Coding	1
319	AP2S1	Adaptor Related Protein Complex 2 Subunit Sigma 1	Protein Coding	1
320	CLTA	Clathrin Light Chain A	Protein Coding	1
321	CLTC	Clathrin Heavy Chain	Protein Coding	1
322	AP1S3	Adaptor Related Protein Complex 1 Subunit Sigma 3	Protein Coding	1
323	CTSB	Cathepsin B	Protein Coding	1
324	CTSD	Cathepsin D	Protein Coding	1
325	CTSE	Cathepsin E	Protein Coding	1
326	CTSH	Cathepsin H	Protein Coding	1
327	CTSK	Cathepsin K	Protein Coding	1
328	CTSL	Cathepsin L	Protein Coding	1
329	CTSV	Cathepsin V	Protein Coding	1
330	CTSO	Cathepsin O	Protein Coding	1
331	CTSS	Cathepsin S	Protein Coding	1
332	AP2A1	Adaptor Related Protein Complex 2 Subunit Alpha 1	Protein Coding	1
333	AP2A2	Adaptor Related Protein Complex 2 Subunit Alpha 2	Protein Coding	1
334	AP1B1	Adaptor Related Protein Complex 1 Subunit Beta 1	Protein Coding	1
335	AP2B1	Adaptor Related Protein Complex 2 Subunit Beta 1	Protein Coding	1
336	AP1G1	Adaptor Related Protein Complex 1 Subunit Gamma 1	Protein Coding	1
337	DNM1	Dynamin 1	Protein Coding	1
338	DNM2	Dynamin 2	Protein Coding	1
339	SEC31A	SEC31 Homolog A, COPII Component	Protein Coding	1
340	DNM3	Dynamin 3	Protein Coding	1
341	HLA-DMA	Major Histocompatibility Complex, Class II, DM Alpha	Protein Coding	1
342	HLA-DMB	Major Histocompatibility Complex, Class II, DM Beta	Protein Coding	1
343	HLA-DOA	Major Histocompatibility Complex, Class II, DO Alpha	Protein Coding	1
344	HLA-DOB	Major Histocompatibility Complex, Class II, DO Beta	Protein Coding	1
345	HLA-DPA1	Major Histocompatibility Complex, Class II, DP Alpha 1	Protein Coding	1
346	HLA-DPB1	Major Histocompatibility Complex, Class II, DP Beta 1	Protein Coding	1
347	HLA-DQA1	Major Histocompatibility Complex, Class II, DQ Alpha 1	Protein Coding	1
348	HLA-DQA2	Major Histocompatibility Complex, Class II, DQ Alpha 2	Protein Coding	1
349	HLA-DQB1	Major Histocompatibility Complex, Class II, DQ Beta 1	Protein Coding	1
350	HLA-DQB2	Major Histocompatibility Complex, Class II, DQ Beta 2	Protein Coding	1
351	HLA-DRA	Major Histocompatibility Complex, Class II, DR Alpha	Protein Coding	1
352	HLA-DRB1	Major Histocompatibility Complex, Class II, DR Beta 1	Protein Coding	1
353	HLA-DRB3	Major Histocompatibility Complex, Class II, DR Beta 3	Protein Coding	1
354	HLA-DRB4	Major Histocompatibility Complex, Class II, DR Beta 4	Protein Coding	1
355	HLA-DRB5	Major Histocompatibility Complex, Class II, DR Beta 5	Protein Coding	1
356	LAG3	Lymphocyte Activating 3	Protein Coding	1
357	SAR1B	Secretion Associated Ras Related GTPase 1B	Protein Coding	1
358	CTSA	Cathepsin A	Protein Coding	1
359	LGMN	Legumain	Protein Coding	1
360	SEC13	SEC13 Homolog, Nuclear Pore And COPII Component	Protein Coding	1
361	SH3GL2	SH3 Domain Containing GRB2 Like 2, Endophilin A1	Protein Coding	1
362	SPTBN2	Spectrin Beta, Non-Erythrocytic 2	Protein Coding	1
363	RAB7A	RAB7A, Member RAS Oncogene Family	Protein Coding	1
364	CANX	Calnexin	Protein Coding	1
365	RILP	Rab Interacting Lysosomal Protein	Protein Coding	1
366	CTSF	Cathepsin F	Protein Coding	1
367	AP1S2	Adaptor Related Protein Complex 1 Subunit Sigma 2	Protein Coding	1
368	AP1M1	Adaptor Related Protein Complex 1 Subunit Mu 1	Protein Coding	1
369	SEC24C	SEC24 Homolog C, COPII Component	Protein Coding	1
370	CD74	CD74 Molecule	Protein Coding	1
371	SEC24D	SEC24 Homolog D, COPII Component	Protein Coding	1

Disorders associated with Golgi-to-ER retrograde transport SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Congenital fibrosis of the extraocular muscles	Enrichment	KIF21A, TUBA1A, TUBB2B, TUBB3	8.26
2	Lissencephaly	Enrichment	DYNC1H1, PAFAH1B1, TUBA1A, TUBA3E, TUBB2B, TUBB3	7.40
3	Tubulinopathy-associated dysgyria	Enrichment	TUBA1A, TUBB2B, TUBB3	7.06
4	Tubulinopathy	Enrichment	TUBA1A, TUBB2A, TUBB2B	6.46
5	Delta beta-thalassemia	Enrichment	HBB, HBD, HBG1	5.71
6	Warburg micro syndrome 1	Enrichment	RAB18, RAB3GAP1, RAB3GAP2	5.43
7	Hereditary persistence of fetal hemoglobin-beta-thalassemia syndrome	Enrichment	HBB, HBG1, HBG2	5.12
8	Hereditary persistence of fetal hemoglobin-sickle cell disease syndrome	Enrichment	HBB, HBG1, HBG2	4.72
9	Anemia, congenital dyserythropoietic, type iiia	Enrichment	KIF23, RACGAP1	4.70
10	Narcolepsy 1	Enrichment	CTSH, HLA-DQB1, HLA-DRB1	4.37
11	Infantile liver failure syndrome	Enrichment	NBAS, RINT1	4.27
12	Essential thrombocythemia	Enrichment	JAK2, SH2B3, TP53	4.19
13	Celiac disease 1	Enrichment	HLA-DQA1, HLA-DQB1	4.07
14	Bullous pemphigoid	Enrichment	HLA-DQB1, HLA-DRB1	4.07
15	Pediatric multiple sclerosis	Enrichment	HLA-DQB1, HLA-DRB1	4.07
16	Spinal muscular atrophy with lower extremity predominant	Enrichment	BICD2, DYNC1H1	4.01
17	Glioma susceptibility 1	Enrichment	H3-3A, H3C1, TP53	3.99
18	Fetal hemoglobin quantitative trait locus 1	Enrichment	HBB, HBG1, HBG2	3.99
19	Multisystem inflammatory syndrome in children	Enrichment	IFNA21, IFNA4, IFNA6, IFNB1	3.84
20	Acute basophilic leukemia	Enrichment	GATA1, MYB	3.81
21	Hemoglobin lepore-beta-thalassemia syndrome	Enrichment	HBB, HBD	3.81
22	Bryant-li-bhoj neurodevelopmental syndrome 2	Enrichment	H3-3A, H3-3B	3.81
23	Sickle cell s-lepore disease	Enrichment	HBB, HBD	3.81
24	Microcephaly	Enrichment	ARF3, COPB1, DYNC1H1, KIF11, KIF23, PLA2G6, TUBB4A	3.67
25	Mednik syndrome	Enrichment	AP1B1, AP1S1	3.59
26	Tetralogy of fallot	Enrichment	GATA4, GATA5, GATA6, ZFPM2	3.54
27	Polymicrogyria, bilateral perisylvian, x-linked	Enrichment	TUBA1A, TUBB2B	3.39
28	Idiopathic achalasia	Enrichment	HLA-DQA1, HLA-DQB1	3.29
29	Bilateral perisylvian polymicrogyria	Enrichment	TUBA1A, TUBB2B	3.15
30	Narcolepsy 2	Enrichment	HLA-DQB1, HLA-DRB1	3.08
31	Autosomal dominant macrothrombocytopenia	Enrichment	TUBA8, TUBB1	3.06
32	Hereditary spastic paraplegia	Enrichment	KIF1A, KIF1C, KIF5A	3.06
33	Erythrocytosis, familial, 1	Enrichment	JAK2, SH2B3	3.04
34	Martsolf syndrome 1	Enrichment	RAB3GAP1, RAB3GAP2	3.02
35	Granulomatosis with polyangiitis	Enrichment	HLA-DPA1, HLA-DPB1	2.90
36	Congenital heart defects, multiple types, 4	Enrichment	GATA4, GATA6	2.82
37	Acute megakaryocytic leukemia	Enrichment	GATA1, TP53	2.82
38	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	KIF1A, KIF5A, MFN2	2.79
39	Spastic ataxia	Enrichment	KIF1A, KIF1C, TUBB3	2.76
40	Conotruncal heart malformations	Enrichment	GATA6, ZFPM2	2.64
41	Adrenocortical carcinoma	Enrichment	PRKAR1A, TP53	2.64
42	Cryptorchidism	Enrichment	RAB3GAP1, TUBA1A	2.58
43	Myelofibrosis	Enrichment	JAK2, SH2B3	2.50
44	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	ABL1, TP53	2.50
45	Familial atrial fibrillation	Enrichment	GATA4, GATA5, GATA6	2.49
46	Cryptorchidism, unilateral or bilateral	Enrichment	RAB3GAP1, TUBA1A	2.48
47	Auditory neuropathy	Enrichment	KIF5A, MFN2, TUBB4A	2.39
48	Fibrosis of extraocular muscles, congenital, 1	Enrichment	KIF21A	2.35
49	Charcot-marie-tooth disease, axonal, type 2a1	Enrichment	KIF1B	2.35
50	Microcephaly with or without chorioretinopathy, lymphedema, or impaired intellectual development	Enrichment	KIF11	2.35
51	Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement	Enrichment	TUBB3	2.35
52	Intellectual developmental disorder, x-linked 100	Enrichment	KIF4A	2.35
53	Spastic paraplegia 10, autosomal dominant	Enrichment	KIF5A	2.35
54	Taurodontism, microdontia, and dens invaginatus	Enrichment	KIF4A	2.35
55	Macrothrombocytopenia, isolated, 1, autosomal dominant	Enrichment	TUBB1	2.35
56	Neuroblastoma 1	Enrichment	KIF1B	2.35
57	Cortical dysplasia, complex, with other brain malformations 3	Enrichment	KIF2A	2.35
58	Cardiomyopathy, familial restrictive, 6	Enrichment	KIF20A	2.35
59	Leber congenital amaurosis with early-onset deafness	Enrichment	TUBB4B	2.35
60	Oocyte/zygote/embryo maturation arrest 24	Enrichment	TUBA1C	2.35
61	Myoclonus, intractable, neonatal	Enrichment	KIF5A	2.35
62	Cortical dysplasia, complex, with other brain malformations 11	Enrichment	KIF26A	2.35
63	Cholestasis, progressive familial intrahepatic, 8	Enrichment	KIF12	2.35
64	Spondyloepimetaphyseal dysplasia with joint laxity, type 2	Enrichment	KIF22	2.35
65	Amyotrophic lateral sclerosis 25	Enrichment	KIF5A	2.35
66	Ocular motility disease	Enrichment	KIF21A	2.35
67	Cortical dysplasia, complex, with other brain malformations 7	Enrichment	TUBB2B	2.35
68	Charcot-marie-tooth disease type 2a1	Enrichment	KIF1B	2.35
69	Retinitis pigmentosa 89	Enrichment	KIF3B	2.35
70	Oocyte/zygote/embryo maturation arrest 23	Enrichment	TUBA4A	2.35
71	Frontotemporal dementia and/or amyotrophic lateral sclerosis 9	Enrichment	TUBA4A	2.35
72	Microcephaly 13, primary, autosomal recessive	Enrichment	CENPE	2.35
73	Facial palsy, congenital, with ptosis and velopharyngeal dysfunction	Enrichment	TUBB6	2.35
74	Spastic paraplegia 30b, autosomal recessive	Enrichment	KIF1A	2.35
75	Macrothrombocytopenia, isolated, 2, autosomal dominant	Enrichment	TUBA8	2.35
76	Braddock-carey syndrome 2	Enrichment	KIF15	2.35
77	Lissencephaly due to tuba1a mutation	Enrichment	TUBA1A	2.35
78	Congenital myopathy 26	Enrichment	TUBA4A	2.35
79	Spastic ataxia 11, autosomal dominant	Enrichment	TUBA4A	2.35
80	Amyotrophic lateral sclerosis type 22	Enrichment	TUBA4A	2.35
81	Neurodegeneration, early-childhood-onset, with retinitis pigmentosa, sensorineural hearing loss, and demyelinating peripheral neuropathy	Enrichment	KLC4	2.35
82	21q22.11q22.12 microdeletion syndrome	Enrichment	KIF15	2.35
83	Congenital dyserythropoietic anemia type iiib	Enrichment	RACGAP1	2.35
84	Polymicrogyria with optic nerve hypoplasia	Enrichment	TUBA8	2.35
85	Anemia, congenital dyserythropoietic, type iiib, autosomal recessive	Enrichment	RACGAP1	2.35
86	Autosomal dominant charcot-marie-tooth disease type 2 due to kif5a mutation	Enrichment	KIF5A	2.35
87	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	2.28
88	Charcot-marie-tooth disease	Enrichment	DCTN1, DNM2, DYNC1H1	2.19
89	Autosomal dominant non-syndromic intellectual disability	Enrichment	ARF3, CUX1, DYNC1H1, KIF1A	2.18
90	Multiple sclerosis	Enrichment	HLA-DQB1, HLA-DRB1	2.14
91	Osteoporosis, childhood- or juvenile-onset, with developmental delay	Enrichment	COPB2	2.13
92	Developmental and epileptic encephalopathy 107	Enrichment	NAPB	2.13
93	Microcephaly 19, primary, autosomal recessive	Enrichment	COPB2	2.13
94	Charcot-marie-tooth disease, axonal, type 2gg	Enrichment	GBF1	2.13
95	Infantile liver failure syndrome 3	Enrichment	RINT1	2.13
96	Short stature-micrognathia syndrome	Enrichment	ARCN1	2.13
97	Autoinflammation and autoimmunity, systemic, with immune dysregulation	Enrichment	COPA	2.13
98	Baralle-macken syndrome	Enrichment	COPB1	2.13
99	Immunodeficiency 128	Enrichment	COPG1	2.13
100	Spondyloepiphyseal dysplasia, holling type	Enrichment	BNIP1	2.13
101	Myelodysplastic syndrome	Enrichment	GATA2, TP53	2.10
102	Neuronal ceroid lipofuscinosis	Enrichment	CTSD, CTSF	2.08
103	Dystonia 4, torsion, autosomal dominant	Enrichment	TUBB4A	2.05
104	Microcephaly and chorioretinopathy, autosomal recessive, 1	Enrichment	KIF11	2.05
105	Spastic paraplegia, optic atrophy, and neuropathy	Enrichment	KLC2	2.05
106	Melanoma, cutaneous malignant 6	Enrichment	KLC1	2.05
107	Muscular dystrophy, limb-girdle, autosomal recessive 3	Enrichment	TUBA1A	2.05
108	Nescav syndrome	Enrichment	KIF1A	2.05
109	Peho syndrome	Enrichment	KIF1A	2.05
110	Keratoconus 9	Enrichment	TUBA3D	2.05
111	Autosomal recessive limb-girdle muscular dystrophy type 2d	Enrichment	TUBA1A	2.05
112	Spastic paraplegia 30a, autosomal dominant	Enrichment	KIF1A	2.05
113	Microcephaly and chorioretinopathy 1	Enrichment	KIF11	2.05
114	Lissencephaly 3	Enrichment	TUBA1A	2.05
115	Frontotemporal dementia and/or amyotrophic lateral sclerosis 4	Enrichment	KIF5A	2.05
116	Cortical dysplasia, complex, with other brain malformations 1	Enrichment	TUBB3	2.05
117	Neuropathy, hereditary sensory, type iic	Enrichment	KIF1A	2.05
118	Torsion dystonia 4	Enrichment	TUBB4A	2.05
119	Hereditary spastic paraplegia 30	Enrichment	KIF1A	2.05
120	Demyelinating polyneuropathy	Enrichment	KIF5A	2.05
121	Skeletal muscle disease	Enrichment	KIF5B	2.05
122	Continuous spikes and waves during sleep	Enrichment	TUBA1A	2.05
123	Keratolytic winter erythema	Enrichment	CTSB	2.03
124	Perry syndrome	Enrichment	DCTN1	2.03
125	Keratitis-ichthyosis-deafness syndrome, autosomal recessive	Enrichment	AP1B1	2.03
126	Hypocalciuric hypercalcemia, familial, type iii	Enrichment	AP2S1	2.03
127	Spinocerebellar ataxia 5	Enrichment	SPTBN2	2.03
128	Pycnodysostosis	Enrichment	CTSK	2.03
129	Craniolenticulosutural dysplasia	Enrichment	SEC23A	2.03
130	Charcot-marie-tooth disease, dominant intermediate b	Enrichment	DNM2	2.03
131	Ceroid lipofuscinosis, neuronal, 10	Enrichment	CTSD	2.03
132	Cole-carpenter syndrome 2	Enrichment	SEC24D	2.03
133	Ceroid lipofuscinosis, neuronal, 13	Enrichment	CTSF	2.03
134	Halperin-birk syndrome	Enrichment	SEC31A	2.03
135	Charcot-marie-tooth disease, axonal, type 2b	Enrichment	RAB7A	2.03
136	Charcot-marie-tooth disease type 2b	Enrichment	RAB7A	2.03
137	Spinocerebellar ataxia, autosomal recessive 14	Enrichment	SPTBN2	2.03
138	Usmani-riazuddin syndrome, autosomal recessive	Enrichment	AP1G1	2.03
139	Pulmonary alveolar proteinosis, acquired	Enrichment	HLA-DRB1	2.03
140	Neuronopathy, distal hereditary motor, autosomal dominant 14	Enrichment	DCTN1	2.03
141	Lethal congenital contracture syndrome 5	Enrichment	DNM2	2.03
142	Psoriasis 15, pustular	Enrichment	AP1S3	2.03
143	Graham little-piccardi-lassueur syndrome	Enrichment	HLA-DRA	2.03
144	Dync1h1-related disorders	Enrichment	DYNC1H1	2.03
145	Usmani-riazuddin syndrome, autosomal dominant	Enrichment	AP1G1	2.03
146	Berylliosis	Enrichment	HLA-DPB1	2.03
147	Neurodevelopmental disorder with microcephaly and structural brain anomalies	Enrichment	DYNC1I2	2.03
148	Autosomal dominant charcot-marie-tooth disease type 2m	Enrichment	DNM2	2.03
149	Cathepsin a-related arteriopathy-strokes-leukoencephalopathy	Enrichment	CTSA	2.03
150	Lip and oral cavity carcinoma	Enrichment	ABL1, TP53	2.02
151	Osteopetrosis and infantile neuroaxonal dystrophy	Enrichment	PLA2G6	2.01
152	Warburg micro syndrome 2	Enrichment	RAB3GAP2	2.01
153	Neurodegeneration with brain iron accumulation 2a	Enrichment	PLA2G6	2.01
154	Spinal muscular atrophy, lower extremity-predominant, 2b, prenatal onset, autosomal dominant	Enrichment	BICD2	2.01
155	Spinal muscular atrophy, lower extremity-predominant, 2a, childhood onset, autosomal dominant	Enrichment	BICD2	2.01
156	Martsolf syndrome 2	Enrichment	RAB3GAP1	2.01
157	Parkinson disease 14, autosomal recessive	Enrichment	PLA2G6	2.01
158	Neurodegeneration with brain iron accumulation 2b	Enrichment	PLA2G6	2.01
159	Cytosolic phospholipase-a2 alpha deficiency associated bleeding disorder	Enrichment	PLA2G4A	2.01
160	Congenital disorder of glycosylation, type iit	Enrichment	GALNT2	2.01
161	Warburg micro syndrome 3	Enrichment	RAB18	2.01
162	Gastrointestinal ulceration, recurrent, with dysfunctional platelets	Enrichment	PLA2G4A	2.01
163	Autosomal dominant distal hereditary motor neuronopathy	Enrichment	BICD2	2.01
164	Autosomal recessive spastic paraplegia type 69	Enrichment	RAB3GAP2	2.01
165	Cryptogenic multifocal ulcerous stenosing enteritis	Enrichment	PLA2G4A	2.01
166	Lissencephaly due to lis1 mutation	Enrichment	PAFAH1B1	2.01
167	Diaphragmatic hernia, congenital	Enrichment	GATA6, ZFPM2	1.95
168	Protein-deficiency anemia	Enrichment	GATA1, HBB	1.95
169	Fetal akinesia deformation sequence 1	Enrichment	KIF21A, TUBA1A	1.92
170	Acrodysostosis 1 with or without hormone resistance	Enrichment	PRKAR1A	1.90
171	Baraitser-winter syndrome 1	Enrichment	ACTB	1.90
172	Anemia, congenital, nonspherocytic hemolytic, 9	Enrichment	GATA1	1.90
173	Thrombocytopenia, x-linked, with or without dyserythropoietic anemia	Enrichment	GATA1	1.90
174	Autoinflammatory disease, multisystem, with immune dysregulation, x-linked	Enrichment	DOCK11	1.90
175	Thrombocytopenia with beta-thalassemia, x-linked	Enrichment	GATA1	1.90
176	Carney complex, type 1	Enrichment	PRKAR1A	1.90
177	Lissencephaly 7 with cerebellar hypoplasia	Enrichment	CDK5	1.90
178	Atrioventricular septal defect 4	Enrichment	GATA4	1.90
179	Atrioventricular septal defect 5	Enrichment	GATA6	1.90
180	Congenital heart defects, multiple types, 5	Enrichment	GATA5	1.90
181	Bone marrow failure syndrome 5	Enrichment	TP53	1.90
182	Anemia, x-linked, with or without neutropenia and/or platelet abnormalities	Enrichment	GATA1	1.90
183	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	1.90
184	Lymphedema, primary, with myelodysplasia	Enrichment	GATA2	1.90
185	Papilloma of choroid plexus	Enrichment	TP53	1.90
186	Basal cell carcinoma 7	Enrichment	TP53	1.90
187	Myelofibrosis, congenital, with anemia, neutropenia, developmental delay, and ocular abnormalities	Enrichment	RBSN	1.90
188	Anaplastic thyroid carcinoma	Enrichment	TP53	1.90
189	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	1.90
190	Myxoma, intracardiac	Enrichment	PRKAR1A	1.90
191	Multiple symmetric lipomatosis	Enrichment	MFN2	1.90
192	Immunodeficiency 40	Enrichment	DOCK2	1.90
193	Charcot-marie-tooth disease, axonal, autosomal dominant, type 2a2a	Enrichment	MFN2	1.90
194	Becker nevus syndrome	Enrichment	ACTB	1.90
195	Dystonia-deafness syndrome 1	Enrichment	ACTB	1.90
196	Atrial septal defect 2	Enrichment	GATA4	1.90
197	Immunodeficiency 21	Enrichment	GATA2	1.90
198	Intellectual developmental disorder with behavioral abnormalities and craniofacial dysmorphism with or without seizures	Enrichment	PHF21A	1.90
199	Cleft palate, psychomotor retardation, and distinctive facial features	Enrichment	KDM1A	1.90
200	Testicular anomalies with or without congenital heart disease	Enrichment	GATA4	1.90
201	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	1.90
202	Ductal carcinoma in situ	Enrichment	TP53	1.90
203	Atrial septal defect 9	Enrichment	GATA6	1.90
204	Neutropenia, severe congenital, 5, autosomal recessive	Enrichment	VPS45	1.90
205	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	1.90
206	8p23.1 microdeletion syndrome	Enrichment	GATA4	1.90
207	Takenouchi-kosaki syndrome	Enrichment	CDC42	1.90
208	Bryant-li-bhoj neurodevelopmental syndrome 1	Enrichment	H3-3A	1.90
209	Charcot-marie-tooth disease, axonal, autosomal recessive, type 2a2b	Enrichment	MFN2	1.90
210	Deafness-lymphedema-leukemia syndrome	Enrichment	GATA2	1.90
211	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	1.90
212	Neurodevelopmental disorder with impaired intellectual development, hypotonia, and ataxia	Enrichment	DOCK3	1.90
213	Sickle cell-beta-thalassemia disease syndrome	Enrichment	HBB	1.90
214	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	1.90
215	Acute megakaryoblastic leukemia in children with down syndrome	Enrichment	GATA1	1.90
216	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	1.90
217	Baraitser-winter syndrome	Enrichment	ACTB	1.90
218	Palatal anomalies-widely spaced teeth-facial dysmorphism-developmental delay syndrome	Enrichment	KDM1A	1.90
219	Charcot-marie-tooth disease type 5	Enrichment	MFN2	1.90
220	Thrombocytopenia with congenital dyserythropoietic anemia	Enrichment	GATA1	1.90
221	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	1.90
222	Chromosome 15q24 deletion syndrome	Enrichment	SIN3A	1.90
223	Prkar1b-related neurodegenerative dementia with intermediate filaments	Enrichment	PRKAR1B	1.90
224	Hemoglobin c-beta-thalassemia syndrome	Enrichment	HBB	1.90
225	Kariminejad neurodevelopmental syndrome	Enrichment	RBSN	1.90
226	Acth-independent macronodular adrenal hyperplasia 3	Enrichment	KDM1A	1.90
227	Choroid plexus cancer	Enrichment	TP53	1.90
228	Charcot-marie-tooth disease type 2a2b	Enrichment	MFN2	1.90
229	Central nervous system germinoma	Enrichment	JMJD1C	1.90
230	Severe congenital neutropenia 5	Enrichment	VPS45	1.90
231	Sickle cell s-o arab disease	Enrichment	HBB	1.90
232	Congenital smooth muscle hamartoma	Enrichment	ACTB	1.90
233	Sickle cell-beta zero-thalassemia	Enrichment	HBB	1.90
234	Nocarh syndrome	Enrichment	CDC42	1.90
235	Partial atrioventricular septal defect with ventricular hypoplasia	Enrichment	GATA4	1.90
236	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	1.90
237	Growth retardation-mild developmental delay-chronic hepatitis syndrome	Enrichment	SH2B3	1.90
238	Pleomorphic xanthoastrocytoma	Enrichment	TP53	1.90
239	Sickle cell s-d punjab disease	Enrichment	HBB	1.90
240	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	1.90
241	Sickle cell s-c disease	Enrichment	HBB	1.90
242	Severe early-onset obesity-insulin resistance syndrome due to sh2b1 deficiency	Enrichment	SH2B1	1.90
243	Hemoglobinopathy toms river	Enrichment	HBG2	1.90
244	Sickle cell s-e disease	Enrichment	HBB	1.90
245	Temporomandibular joint anomaly	Enrichment	DOCK1	1.90
246	Homozygous hemoglobin o arab disease	Enrichment	HBB	1.90
247	Sickle cell s-other specified hemoglobin variant	Enrichment	HBB	1.90
248	Cerebral palsy	Enrichment	MFN2, TUBA1A, TUBB4A	1.90
249	Heart disease	Enrichment	ABL1, GATA4	1.89
250	46,xy partial gonadal dysgenesis	Enrichment	GATA4, ZFPM2	1.89
251	Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss	Enrichment	TUBB1	1.87
252	Leukodystrophy, hypomyelinating, 6	Enrichment	TUBB4A	1.87
253	Spastic ataxia 2, autosomal recessive	Enrichment	KIF1C	1.87
254	Oocyte/zygote/embryo maturation arrest 2	Enrichment	TUBB8	1.87
255	Cortical dysplasia, complex, with other brain malformations 5	Enrichment	TUBB2A	1.87
256	Spastic ataxia 2	Enrichment	KIF1C	1.87
257	Leukemia, acute myeloid	Enrichment	GATA2, JAK2, TP53	1.87
258	Amyotrophy, hereditary neuralgic	Enrichment	NAPB	1.83
259	Cataract 11, multiple types	Enrichment	GBF1	1.83
260	Anterior segment dysgenesis 1	Enrichment	GBF1	1.83
261	Short stature, optic nerve atrophy, and pelger-huet anomaly	Enrichment	NBAS	1.83
262	Osteogenesis imperfecta, type xxi	Enrichment	KDELR2	1.83
263	Periventricular nodular heterotopia 8	Enrichment	ARF1	1.83
264	Developmental and epileptic encephalopathy 96	Enrichment	NSF	1.83
265	Infantile liver failure syndrome 2	Enrichment	NBAS	1.83
266	Achondrogenesis, type ia	Enrichment	TRIP11	1.82
267	Congenital disorder of glycosylation, type iil	Enrichment	COG6	1.82
268	Odontochondrodysplasia 1	Enrichment	TRIP11	1.82
269	Congenital disorder of glycosylation, type iij	Enrichment	COG4	1.82
270	Congenital disorder of glycosylation, type iiq	Enrichment	COG2	1.82
271	Saul-wilson syndrome	Enrichment	COG4	1.82
272	Congenital disorder of glycosylation, type iiaa	Enrichment	STX5	1.82
273	Shaheen syndrome	Enrichment	COG6	1.82
274	Cog4-congenital disorder of glycosylation	Enrichment	COG4	1.82
275	Pontocerebellar hypoplasia, type 13	Enrichment	VPS51	1.82
276	Congenital disorder of glycosylation, type iibb	Enrichment	COG3	1.82
277	Cog6-congenital disorder of glycosylation	Enrichment	COG6	1.82
278	Hypohidrosis-enamel hypoplasia-palmoplantar keratoderma-intellectual disability syndrome	Enrichment	COG6	1.82
279	Gastric cancer	Enrichment	IRF1, RAD51C, TP53	1.78
280	Neuropathy, hereditary sensory and autonomic, type iia	Enrichment	KIF1A	1.75
281	Hereditary sensory and autonomic neuropathy type 2	Enrichment	KIF1A	1.75
282	Periodontitis, aggressive, 1	Enrichment	CTSC	1.73
283	Spinal muscular atrophy, lower extremity-predominant, 1, autosomal dominant	Enrichment	DYNC1H1	1.73
284	Haim-munk syndrome	Enrichment	CTSC	1.73
285	Papillon-lefevre syndrome	Enrichment	CTSC	1.73
286	Chylomicron retention disease	Enrichment	SAR1B	1.73
287	Fanconi anemia, complementation group n	Enrichment	DCTN5	1.73
288	Creutzfeldt-jakob disease	Enrichment	HLA-DQB1	1.73
289	Galactosialidosis	Enrichment	CTSA	1.73
290	Sarcoidosis 1	Enrichment	HLA-DRB1	1.73
291	Pancreatic cancer 3	Enrichment	DCTN5	1.73
292	Neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies	Enrichment	DYNC1I2	1.73
293	Cortical dysplasia, complex, with other brain malformations 13	Enrichment	DYNC1H1	1.73
294	Psoriasis 14, pustular	Enrichment	AP1S3	1.73
295	Pettigrew syndrome	Enrichment	AP1S2	1.73
296	Charcot-marie-tooth disease, axonal, type 2o	Enrichment	DYNC1H1	1.73
297	Intellectual developmental disorder, autosomal dominant 60, with seizures	Enrichment	AP2M1	1.73
298	Distal hereditary motor neuropathy type 7	Enrichment	DCTN1	1.73
299	Combined deficiency of sialidase and beta galactosidase	Enrichment	CTSA	1.73
300	Lissencephaly 1	Enrichment	PAFAH1B1	1.71
301	Intellectual developmental disorder, autosomal dominant 45	Enrichment	PAFAH1B3	1.71
302	Infantile osteopetrosis with neuroaxonal dysplasia	Enrichment	PLA2G6	1.71
303	Congenital nervous system abnormality	Enrichment	DYNC1H1, PLA2G6, TUBA1A, TUBB4A	1.68
304	Nervous system disease	Enrichment	DYNC1H1, PLA2G6, TUBA1A, TUBB4A	1.68
305	Patent foramen ovale	Enrichment	GATA4, GATA6	1.68
306	Uvula, bifid	Enrichment	ARF3	1.66
307	Kyphosis	Enrichment	ARF3	1.66
308	Acute liver failure	Enrichment	RINT1	1.66
309	Multiple endocrine neoplasia, type iia	Enrichment	KIF1B	1.65
310	Kearns-sayre syndrome	Enrichment	KIF5B	1.65
311	Female infertility due to oocyte meiotic arrest	Enrichment	TUBB8	1.65
312	Primary autosomal recessive microcephaly	Enrichment	CENPE, COPB2	1.64
313	Myeloproliferative syndrome, transient	Enrichment	GATA1	1.60
314	Hypoparathyroidism, sensorineural deafness, and renal dysplasia syndrome	Enrichment	GATA3	1.60
315	Adrenocortical carcinoma, hereditary	Enrichment	TP53	1.60
316	Amelogenesis imperfecta, type ig	Enrichment	PRKAR1A	1.60
317	Porphyria, congenital erythropoietic	Enrichment	GATA1	1.60
318	Cervical cancer	Enrichment	TP53	1.60
319	Pigmented nodular adrenocortical disease, primary, 1	Enrichment	PRKAR1A	1.60
320	Lipomatosis, multiple symmetric, with or without axonal peripheral neuropathy	Enrichment	MFN2	1.60
321	Chromosome 16p11.2 deletion syndrome, 220-kb	Enrichment	SH2B1	1.60
322	46,xy sex reversal 9	Enrichment	ZFPM2	1.60
323	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	1.60
324	Lymphoma, hodgkin, classic	Enrichment	TP53	1.60
325	Thrombocythemia 3	Enrichment	JAK2	1.60
326	Cyanosis, transient neonatal	Enrichment	HBG2	1.60
327	Adams-oliver syndrome 2	Enrichment	DOCK6	1.60
328	Neutropenia, severe congenital, 8, autosomal dominant	Enrichment	GATA6	1.60
329	Marbach-schaaf neurodevelopmental syndrome	Enrichment	PRKAR1B	1.60
330	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	1.60
331	Congenital heart defects and skeletal malformations syndrome	Enrichment	ABL1	1.60
332	Usher syndrome, type iv	Enrichment	PRKAR1A	1.60
333	Acrodysostosis	Enrichment	PRKAR1A	1.60
334	Chromosome 16p11.2 deletion syndrome, 593-kb	Enrichment	SH2B1	1.60
335	Congenital fibrosarcoma	Enrichment	TP53	1.60
336	46,xy sex reversal 3	Enrichment	GATA4	1.60
337	Hypobetalipoproteinemia, familial, 2	Enrichment	DOCK7	1.60
338	Li-fraumeni syndrome 1	Enrichment	TP53	1.60
339	Sarcoma	Enrichment	TP53	1.60
340	Witteveen-kolk syndrome	Enrichment	SIN3A	1.60
341	Fibrolamellar carcinoma	Enrichment	PRKACA	1.60
342	Angiocentric glioma	Enrichment	MYB	1.60
343	Axonal neuropathy	Enrichment	MFN2	1.60
344	Developmental and epileptic encephalopathy 23	Enrichment	DOCK7	1.60
345	Cervix carcinoma	Enrichment	TP53	1.60
346	Immune system disease	Enrichment	CDC42	1.60
347	Hodgkin's lymphoma	Enrichment	TP53	1.60
348	Ciliary dyskinesia, primary, 18	Enrichment	PRKAR1B	1.60
349	B-lymphoblastic leukemia/lymphoma with hyperdiploidy	Enrichment	GATA3	1.60
350	Paget's disease of bone	Enrichment	DOCK6	1.60
351	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB	1.60
352	Hypoparathyroidism-deafness-renal disease syndrome	Enrichment	GATA3	1.60
353	Polycythemia	Enrichment	JAK2	1.60
354	Isolated primary pigmented nodular adrenocortical disease	Enrichment	PRKAR1A	1.60
355	Autosomal dominant nonsyndromic deafness	Enrichment	GATA3	1.60
356	Hypereosinophilic syndrome	Enrichment	JAK2	1.60
357	Immunodeficiency 117	Enrichment	IRF1	1.60
358	Pleomorphic rhabdomyosarcoma	Enrichment	TP53	1.60
359	Multiple system atrophy, cerebellar type	Enrichment	MFN2	1.60
360	Inherited cancer-predisposing syndrome	Enrichment	PRKAR1A, RAD51B, RAD51C, SH2B3, TP53	1.60
361	Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 1	Enrichment	TUBB2B	1.57
362	Early myoclonic encephalopathy	Enrichment	TUBA1A	1.57
363	Multicystic kidney dysplasia	Enrichment	KIF4A	1.57
364	Syndromic rod-cone dystrophy	Enrichment	KIF11	1.57
365	Multicystic dysplastic kidney	Enrichment	KIF4A	1.57
366	Myopathy, centronuclear, x-linked	Enrichment	DNM2	1.56
367	Intellectual developmental disorder, autosomal dominant 56	Enrichment	CLTC	1.56
368	Developmental and epileptic encephalopathy 31b	Enrichment	DNM1	1.56
369	Breast-ovarian cancer, familial 5	Enrichment	DCTN5	1.56
370	Nail disorder, nonsyndromic congenital, 9	Enrichment	CTSK	1.56
371	Adult-onset myasthenia gravis	Enrichment	HLA-DQA1	1.56
372	Cole-carpenter syndrome	Enrichment	SEC24D	1.56
373	Aggressive periodontitis	Enrichment	CTSC	1.56
374	Vogt-koyanagi-harada disease	Enrichment	HLA-DRB1	1.56
375	Band heterotopia	Enrichment	PAFAH1B1	1.53
376	Miller-dieker lissencephaly syndrome	Enrichment	PAFAH1B1	1.53
377	Chromosome 17p13.3, centromeric, duplication syndrome	Enrichment	PAFAH1B1	1.53
378	Distal myopathy	Enrichment	BICD2	1.53
379	Muscular atrophy	Enrichment	BICD2	1.53
380	Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome	Enrichment	SNAP29	1.53
381	Congenital disorder of glycosylation, type iih	Enrichment	COG8	1.53
382	Catifa syndrome	Enrichment	RIC1	1.53
383	Neurodevelopmental disorder with developmental delay and with or without motor or speech delay	Enrichment	CUX1	1.53
384	Smith-mccort dysplasia	Enrichment	RAB33B	1.53
385	Smith-mccort dysplasia 2	Enrichment	RAB33B	1.53
386	Cog8-congenital disorder of glycosylation	Enrichment	COG8	1.53
387	Familial isolated restrictive cardiomyopathy	Enrichment	KIF20A	1.51
388	Hereditary breast ovarian cancer syndrome	Enrichment	RAD51B, RAD51C, TP53	1.50
389	Myeloma, multiple	Enrichment	H3C1, SH2B3, TP53	1.48
390	Diamond-blackfan anemia 1	Enrichment	GATA1, TP53	1.48
391	Precursor t-cell acute lymphoblastic leukemia	Enrichment	ABL1, MYB	1.48
392	Peripheral nervous system disease	Enrichment	DYNC1H1, KIF5A	1.45
393	Neuropathy	Enrichment	DYNC1H1, KIF5A	1.45
394	Neuroblastoma	Enrichment	KIF1B	1.45
395	Liver failure, infantile, transient	Enrichment	NBAS	1.44
396	Temporal arteritis	Enrichment	HLA-DRB1	1.44
397	Neurologic, endocrine, and pancreatic disease, multisystem, infantile-onset 1	Enrichment	CLTC	1.44
398	Systemic-onset juvenile idiopathic arthritis	Enrichment	HLA-DRB1	1.44
399	Thrombocythemia 1	Enrichment	SH2B3	1.43
400	Hyper-ige syndrome 2, autosomal recessive, with recurrent infections	Enrichment	DOCK8	1.43
401	Polycythemia vera	Enrichment	JAK2	1.43
402	Epilepsy, familial temporal lobe, 1	Enrichment	MICAL1	1.43
403	Heart defects, congenital, and other congenital anomalies	Enrichment	GATA6	1.43
404	Osteogenic sarcoma	Enrichment	TP53	1.43
405	Neuropathy, hereditary motor and sensory, type via, with optic atrophy	Enrichment	MFN2	1.43
406	Hypercholanemia, familial 1	Enrichment	DOCK6	1.43
407	Nasopharyngeal carcinoma	Enrichment	TP53	1.43
408	Diaphragmatic hernia 3	Enrichment	ZFPM2	1.43
409	Adams-oliver syndrome 1	Enrichment	DOCK6	1.43
410	Breast-ovarian cancer, familial 3	Enrichment	RAD51C	1.43
411	Fanconi anemia, complementation group o	Enrichment	RAD51C	1.43
412	Hyper-ige syndrome 3, autosomal recessive, with recurrent infections	Enrichment	DOCK8	1.43
413	Breast implant-associated anaplastic large cell lymphoma	Enrichment	JAK2	1.43
414	Atypical teratoid rhabdoid tumor	Enrichment	TP53	1.43
415	Anaplastic astrocytoma	Enrichment	TP53	1.43
416	Hemoglobin e disease	Enrichment	HBB	1.43
417	Squamous cell carcinoma	Enrichment	TP53	1.43
418	T-cell acute lymphoblastic leukemia	Enrichment	ABL1	1.43
419	Adenocarcinoma	Enrichment	TP53	1.43
420	Hereditary site-specific ovarian cancer syndrome	Enrichment	RAD51C	1.43
421	End stage renal disease	Enrichment	GATA3	1.43
422	Bone osteosarcoma	Enrichment	TP53	1.43
423	Adenoid cystic carcinoma	Enrichment	MYB	1.43
424	Cushing syndrome due to bilateral macronodular adrenocortical disease	Enrichment	KDM1A	1.43
425	Sickle cell-hemoglobin c disease	Enrichment	HBB	1.43
426	Hemoglobin d disease	Enrichment	HBB	1.43
427	Unstable hemoglobin disease	Enrichment	HBB	1.43
428	Hyperpigmentation of the skin	Enrichment	MFN2	1.43
429	Hemoglobin e/beta thalassemia disease	Enrichment	HBB	1.43
430	Primary ovarian insufficiency	Enrichment	JAK2, RAD51C, SH2B1	1.42
431	Autosomal dominant cerebellar ataxia	Enrichment	KIF26B	1.40
432	Pelizaeus-merzbacher disease	Enrichment	RAB9B	1.35
433	Spastic paraplegia 2, x-linked	Enrichment	RAB9B	1.35
434	Congenital disorder of glycosylation, type iig	Enrichment	COG1	1.35
435	Leukodystrophy, hypomyelinating, 2	Enrichment	SNAP29	1.35
436	Epilepsy, progressive myoclonic, 6	Enrichment	GOSR2	1.35
437	Muscular dystrophy, congenital, with or without seizures	Enrichment	GOSR2	1.35
438	Cog7-congenital disorder of glycosylation	Enrichment	COG7	1.35
439	Pelizeaus-merzbacher spectrum disorder	Enrichment	RAB9B	1.35
440	Developmental and epileptic encephalopathy 31a	Enrichment	DNM1	1.34
441	Follicular lymphoma	Enrichment	HLA-DRB1	1.34
442	Spinal muscular atrophy	Enrichment	DYNC1H1	1.34
443	Genetic motor neuron disease	Enrichment	DCTN1	1.34
444	Diffuse cutaneous systemic sclerosis	Enrichment	HLA-DRB1	1.34
445	Chromosome 15q11.2 deletion syndrome	Enrichment	PAFAH1B1	1.31
446	Congenital ptosis	Enrichment	RAB3GAP1	1.31
447	Small cell cancer of the lung	Enrichment	TP53	1.31
448	Down syndrome	Enrichment	GATA1	1.31
449	Thyroid cancer, nonmedullary, 1	Enrichment	TP53	1.31
450	Budd-chiari syndrome	Enrichment	JAK2	1.31
451	Potocki-shaffer syndrome	Enrichment	PHF21A	1.31
452	Carney complex variant	Enrichment	PRKAR1A	1.31
453	Sickle cell disease	Enrichment	HBB	1.31
454	Beta-thalassemia, dominant inclusion body type	Enrichment	HBB	1.31
455	Arrhythmogenic right ventricular dysplasia, familial, 10	Enrichment	PRKAR1A	1.31
456	Aminoacylase 1 deficiency	Enrichment	ACTB	1.31
457	Fetal akinesia deformation sequence 3	Enrichment	DOCK7	1.31
458	Erythrocytosis, familial, 6	Enrichment	HBB	1.31
459	Beta-thalassemia intermedia	Enrichment	HBB	1.31
460	Lung sarcomatoid carcinoma	Enrichment	TP53	1.31
461	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	ABL1	1.31
462	Hemoglobinopathy	Enrichment	HBB	1.31
463	Embryonal rhabdomyosarcoma	Enrichment	TP53	1.31
464	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CDC42	1.31
465	Hemoglobin c disease	Enrichment	HBB	1.31
466	Transposition of the great arteries	Enrichment	GATA4	1.31
467	Methemoglobinemia, beta-globin type	Enrichment	HBB	1.31
468	Middle aortic syndrome	Enrichment	GATA6	1.31
469	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB	1.31
470	Congenital hypothyroidism	Enrichment	TUBB1	1.28
471	Myopathy	Enrichment	DNM2, DYNC1H1	1.27
472	Osteogenesis imperfecta, type i	Enrichment	SEC24D	1.26
473	Myopathy, centronuclear, 1	Enrichment	DNM2	1.26
474	Inflammatory myofibroblastic tumor	Enrichment	CLTC	1.26
475	Limited scleroderma	Enrichment	HLA-DRB1	1.26
476	Hypertrichosis	Enrichment	RAB3GAP1	1.24
477	Pseudohypoparathyroidism, type ib	Enrichment	STX16	1.23
478	Congenital disorder of glycosylation, type iii	Enrichment	COG5	1.23
479	Cog5-congenital disorder of glycosylation	Enrichment	COG5	1.23
480	Rhabdomyosarcoma 2	Enrichment	TP53	1.21
481	Ventricular septal defect 1	Enrichment	GATA4	1.21
482	Lymphoma	Enrichment	TP53	1.21
483	Thalassemia	Enrichment	HBB	1.21
484	Myeloproliferative neoplasm	Enrichment	JAK2	1.21
485	Persistent truncus arteriosus	Enrichment	GATA6	1.21
486	Seckel syndrome	Enrichment	CENPE	1.21
487	West syndrome	Enrichment	DNM1, TUBA1A	1.20
488	Noonan syndrome 3	Enrichment	CLTC	1.20
489	Renal cell carcinoma with mit translocations	Enrichment	CLTC	1.20
490	Corpus callosum, agenesis of	Enrichment	TUBA1A	1.18
491	Hydrocephalus	Enrichment	KIF4A	1.18
492	Isolated corpus callosum agenesis	Enrichment	TUBA1A	1.18
493	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	TUBA1A	1.18
494	Breast cancer	Enrichment	KLC1, RAD51C, TP53	1.17
495	Hydrocephalus, congenital, 1	Enrichment	KIF4A	1.16
496	Isolated congenital microcephaly	Enrichment	TUBA3E	1.16
497	Primary bone dysplasia	Enrichment	COPB1	1.15
498	Lennox-gastaut syndrome	Enrichment	DNM1	1.14
499	Pontocerebellar hypoplasia, type 2d	Enrichment	VPS53	1.14
500	Hyperaldosteronism, familial, type i	Enrichment	HBD	1.14
501	Li-fraumeni syndrome	Enrichment	TP53	1.14
502	Methemoglobinemia, beta type	Enrichment	HBB	1.14
503	Double outlet right ventricle	Enrichment	ZFPM2	1.14
504	Breast adenocarcinoma	Enrichment	TP53	1.14
505	Autosomal dominant secondary polycythemia	Enrichment	HBB	1.14
506	Dandy-walker syndrome	Enrichment	TUBA1A	1.13
507	Syndromic intellectual disability	Enrichment	KIF1A	1.13
508	Diamond-blackfan anemia	Enrichment	GATA1, TP53	1.13
509	Pectus excavatum	Enrichment	ARF3	1.11
510	Immune deficiency disease	Enrichment	COPB1	1.11
511	Osteochondrodysplasia	Enrichment	COPB1	1.11
512	Myoclonic-atonic epilepsy	Enrichment	AP2M1	1.09
513	Esophageal cancer	Enrichment	TP53	1.07
514	Squamous cell carcinoma, head and neck	Enrichment	TP53	1.07
515	Leukemia, chronic myeloid	Enrichment	ABL1	1.07
516	Beta-thalassemia	Enrichment	HBB	1.07
517	Adams-oliver syndrome	Enrichment	DOCK6	1.07
518	Beta-thalassemia major	Enrichment	HBB	1.07
519	Gallbladder cancer	Enrichment	TP53	1.07
520	Hemolytic anemia	Enrichment	HBB	1.07
521	Moyamoya angiopathy	Enrichment	ABL1	1.07
522	Amyotrophic lateral sclerosis 1	Enrichment	DCTN1	1.05
523	Polymicrogyria	Enrichment	DYNC1H1	1.05
524	Hereditary paraganglioma-pheochromocytoma syndromes	Enrichment	KIF1B	1.04
525	Attention deficit-hyperactivity disorder	Enrichment	KIF5B	1.02
526	Neurodegeneration with brain iron accumulation	Enrichment	PLA2G6	1.02
527	Undetermined early-onset epileptic encephalopathy	Enrichment	CLTC, DNM1	1.02
528	Heinz body anemias	Enrichment	HBB	1.02
529	Lymphoma, non-hodgkin, familial	Enrichment	TP53	1.02
530	Severe congenital neutropenia	Enrichment	VPS45	1.02
531	Heinz body anemia	Enrichment	HBB	1.02
532	Frontotemporal dementia 1	Enrichment	DCTN1	1.01
533	Periventricular nodular heterotopia	Enrichment	ARF1	1.01
534	Cataract	Enrichment	COPB1	1.01
535	Pontocerebellar hypoplasia, type 2e	Enrichment	VPS53	1.00
536	Movement disease	Enrichment	RAB3GAP1	0.99
537	Digeorge syndrome	Enrichment	SEC24C	0.97
538	Short-rib thoracic dysplasia 3 with or without polydactyly	Enrichment	DYNC1H1	0.97
539	Alpha-thalassemia	Enrichment	HBB	0.97
540	Leukemia, acute lymphoblastic 3	Enrichment	JAK2	0.97
541	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1	0.97
542	Adult hepatocellular carcinoma	Enrichment	TP53	0.97
543	Primary hyperaldosteronism	Enrichment	TP53	0.97
544	Hydrops fetalis, nonimmune	Enrichment	KIF19	0.96
545	Immunodeficiency 47	Enrichment	COG7	0.94
546	Stereotypic movement disorder	Enrichment	DNM1	0.94
547	Leukemia, chronic lymphocytic	Enrichment	TP53	0.93
548	Familial colorectal cancer	Enrichment	TP53	0.93
549	Thrombocytopenia	Enrichment	GATA1, TUBB1	0.92
550	Heart, malformation of	Enrichment	ARF3	0.90
551	Lung non-small cell carcinoma	Enrichment	IRF1	0.89
552	Uterine corpus cancer	Enrichment	RAD51C	0.89
553	Non-immune hydrops fetalis	Enrichment	KIF19	0.88
554	Ovarian cancer	Enrichment	KIF1B, RAD51C, TP53	0.87
555	Progressive myoclonus epilepsy	Enrichment	GOSR2	0.85
556	Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay	Enrichment	PLA2G6	0.83
557	Aortic valve disease 1	Enrichment	GATA5	0.82
558	Hypercholesterolemia, familial, 1	Enrichment	DOCK6	0.82
559	Breast-ovarian cancer, familial 1	Enrichment	RAD51C	0.82
560	Acute promyelocytic leukemia	Enrichment	PRKAR1A	0.82
561	Charcot-marie-tooth disease type 4	Enrichment	DYNC1H1	0.81
562	Leber plus disease	Enrichment	NBAS, TUBB4B	0.81
563	Cleft palate, isolated	Enrichment	RAB3GAP1	0.81
564	Aortic aneurysm, familial thoracic 1	Enrichment	GATA4	0.79
565	Lung cancer susceptibility 3	Enrichment	TP53	0.79
566	Scoliosis	Enrichment	ARF3	0.79
567	Esophageal atresia/tracheoesophageal fistula	Enrichment	RAB3GAP2	0.76
568	Atypical hemolytic-uremic syndrome	Enrichment	HBB	0.76
569	Familial hypercholesterolemia	Enrichment	DOCK6	0.76
570	Hypertrophic cardiomyopathy	Enrichment	KIF5B	0.75
571	Centronuclear myopathy	Enrichment	DNM2	0.75
572	Optic atrophy plus syndrome	Enrichment	TUBB6	0.74
573	Rhabdomyosarcoma	Enrichment	TP53	0.74
574	Gliosarcoma	Enrichment	TP53	0.74
575	Myoclonic epilepsy of unverricht and lundborg	Enrichment	GOSR2	0.72
576	Cleft lip/palate	Enrichment	RIC1	0.72
577	Giant cell glioblastoma	Enrichment	TP53	0.71
578	Beckwith-wiedemann syndrome	Enrichment	MFN2	0.69
579	Diffuse large b-cell lymphoma	Enrichment	TP53	0.67
580	Dystonia	Enrichment	ARF3	0.64
581	Endometrial cancer	Enrichment	RAD51C	0.63
582	Hepatoblastoma	Enrichment	TP53	0.63
583	Severe covid-19	Enrichment	HLA-DQB1	0.62
584	Pontocerebellar hypoplasia	Enrichment	VPS53	0.62
585	Hepatocellular carcinoma	Enrichment	TP53	0.62
586	Malaria	Enrichment	HBB	0.60
587	Cystic fibrosis	Enrichment	DCTN4	0.59
588	Dilated cardiomyopathy	Enrichment	GATA6, KIF5B	0.58
589	Pancreatic cancer	Enrichment	TP53	0.57
590	Developmental and epileptic encephalopathy	Enrichment	SEC24C	0.54
591	Systemic lupus erythematosus	Enrichment	HLA-DRB1	0.52
592	Bladder cancer	Enrichment	TP53	0.51
593	Prostate cancer	Enrichment	TP53	0.51
594	Lung cancer	Enrichment	IRF1	0.48
595	Hereditary breast carcinoma	Enrichment	DCTN5	0.47
596	Severe combined immunodeficiency	Enrichment	DOCK8	0.47
597	Distal arthrogryposis	Enrichment	BICD2	0.47
598	Cakut	Enrichment	GATA3	0.46
599	Differentiated thyroid carcinoma	Enrichment	GOLGA5	0.45
600	Fanconi anemia, complementation group a	Enrichment	RAD51C	0.45
601	Connective tissue disease	Enrichment	TRIP11	0.42
602	Autism	Enrichment	ARF3	0.38
603	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	DCTN1	0.38
604	Joubert syndrome 1	Enrichment	RCOR1	0.33
605	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	GATA4	0.29
606	Colorectal cancer	Enrichment	DCTN5	0.25
607	Deafness, autosomal recessive	Enrichment	GOSR2	0.21
608	Primary ciliary dyskinesia	Enrichment	PRKAR1B	0.21
609	Retinitis pigmentosa	Enrichment	KIF11	0.21
610	Autosomal recessive nonsyndromic deafness	Enrichment	GOSR2	0.21
611	Hereditary retinal dystrophy	Enrichment	KIF11, NBAS	0.20
612	Fundus dystrophy	Enrichment	KIF11, NBAS	0.20
613	Autism spectrum disorder	Enrichment	DYNC1H1	0.19
614	Complex neurodevelopmental disorder	Enrichment	AP1G1	0.16
615	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	GOSR2	0.13

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Golgi-to-ER retrograde transport

Pathway Network for Golgi-to-ER retrograde transport

Pathway network for the Golgi-to-ER retrograde transport SuperPath

Member Pathways for Golgi-to-ER retrograde transport

Pathways in the Golgi-to-ER retrograde transport SuperPath

Gene overlap in member pathways for Golgi-to-ER retrograde transport SuperPath

Associated Genes for Golgi-to-ER retrograde transport

Associated Disorders for Golgi-to-ER retrograde transport

Disorders associated with Golgi-to-ER retrograde transport SuperPath

STRING Interaction Network for Golgi-to-ER retrograde transport

Sources for Golgi-to-ER retrograde transport