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MyD88 dependent cascade initiated on endosome SuperPath

Pathway network for MyD88 dependent cascade initiated on endosome SuperPath
36 Pathways in the MyD88 dependent cascade initiated on endosome SuperPath
IRAK2 mediated activation of TAK1 complex MyD88-independent TLR4 cascade
TRAF6 mediated NF-kB activation MyD88:MAL(TIRAP) cascade initiated on plasma membrane
Activation of IRF3, IRF7 mediated by TBK1, IKBKE MyD88 cascade initiated on plasma membrane
TICAM1-dependent activation of IRF3/IRF7 Toll Like Receptor 4 (TLR4) Cascade
TRAF6-mediated induction of TAK1 complex within TLR4 complex Toll Like Receptor 5 (TLR5) Cascade
Toll Like Receptor 9 (TLR9) Cascade Alpha-protein kinase 1 signaling pathway
TLR3 deficiency - HSE TICAM1 deficiency - HSE
TRIF-mediated programmed cell death Toll Like Receptor TLR6:TLR2 Cascade
MYD88 distinct input-output pathway TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
Toll Like Receptor 10 (TLR10) Cascade TAK1-dependent IKK and NF-kappa-B activation
TLR3-mediated TICAM1-dependent programmed cell death Toll Like Receptor 7/8 (TLR7/8) Cascade
UNC93B1 deficiency - HSE TRAF3 deficiency - HSE
Toll-like Receptor Cascades TICAM1,TRAF6-dependent induction of TAK1 complex
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation Toll Like Receptor 2 (TLR2) Cascade
TRIF(TICAM1)-mediated TLR4 signaling Trafficking and processing of endosomal TLR
Toll Like Receptor 3 (TLR3) Cascade TICAM1, RIP1-mediated IKK complex recruitment
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation Toll Like Receptor TLR1:TLR2 Cascade
MyD88 dependent cascade initiated on endosome Regulation of NF-kappa B signaling
175 Genes in the MyD88 dependent cascade initiated on endosome SuperPath
RPS27A TRAF6 UBA52 UBB UBC TAB1 TAB2 TAB3 MAP3K7 IRAK2 CHUK IKBKB
UBE2N UBE2V1 CASP8 IKBKG TICAM1 IRAK1 PEDS1-UBE2V1 NFKB1 TRAF2 TIFA USP18 IKBIP
AGER NKIRAS2 NKIRAS1 HMGB1 APP NFKB2 NFKBIA NFKBIB RELA S100A12 S100B SAA1
TP53 NLRX1 ALPK1 NLRC5 USP14 N4BP1 LRRC14 NOD1 JUN NOD2 TLR4 RIPK2
MAP3K8 CREB1 ATF2 MAPK14 DUSP3 DUSP4 DUSP6 DUSP7 ELK1 FBXW11 FOS LY96
MEF2A MEF2C ATF1 VRK3 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D MAPK1 MAPK3 MAPK7
MAPK8 MAPK11 MAPK9 MAPK10 MAP2K1 MAP2K3 MAP2K6 MAP2K7 RPS6KA1 RPS6KA2 RPS6KA3 MAP2K4
SKP1 MAPKAPK3 TNIP2 CUL1 BTRC RPS6KA5 MAPKAPK2 CD14 MYD88 MAP3K1 IRAK4 PELI3
ECSIT PELI2 PELI1 TMED7-TICAM2 TICAM2 IRF7 TLR3 RIPK3 TRAF3 RIPK1 TLR7 TLR9
TANK SARM1 TBK1 IRF3 FADD IKBKE TLR6 TLR1 TLR2 BIRC2 BIRC3 UBE2D1
UBE2D2 UBE2D3 IRAK3 TIRAP FGA FGB FGG SIGIRR S100A1 S100A8 S100A9 BTK
SOCS1 CD36 PTPN11 TLR5 TLR10 SFTPD SFTPA1 SFTPA2 TLR8 UNC93B1 DNM1 DNM2
DNM3 ITGAM ITGB2 LBP CD180 PLCG2 PTPN4 BPI LY86 PIK3R4 PIK3C3 RBSN
EEA1 CNPY3 CTSB CTSK CTSL CTSV CTSS LGMN HSP90B1 RIGI MAVS IFIH1
TRIM25 RNF135 TRIM4 IL1A GSDME APOB GSDMD
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network for MyD88 dependent cascade initiated on endosome SuperPath