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PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
SuperPath
Pathway network
for
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
SuperPath
4
Pathways
in the
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
SuperPath
Constitutive Signaling by Aberrant PI3K in Cancer
Negative regulation of the PI3K/AKT network
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
PI3K/AKT Signaling in Cancer
135
Genes
in the
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
SuperPath
NRG3
FRS2
PIK3AP1
NRG4
KLB
HBEGF
EGF
EGFR
ERBB2
ERBB3
ERBB4
EREG
ESR1
ESR2
FGF1
FGF2
FGF3
FGF4
FGF5
FGF6
FGF7
FGF8
FGF9
FGF10
FGFR1
FGFR3
FGFR2
FGFR4
FLT3
FLT3LG
FYN
GAB1
EPGN
FGF20
FGF22
GRB2
ICOS
HGF
NRG1
IRS1
AREG
KIT
RHOG
LCK
MET
KITLG
TRAT1
PDGFA
PDGFB
PDGFRA
PDGFRB
PIK3CA
PIK3CB
PIK3CD
PIK3R1
PIK3R2
PTPN11
RAC1
RAC2
SRC
STRN
BTC
TGFA
VAV1
FGF23
PIK3R3
IRS2
FGF18
FGF17
FGF16
CD19
KL
CD28
CD80
CD86
NRG2
GAB2
FGF19
AKT1
AKT3
AKT2
PIP5K1C
IL1RAP
INS
INSR
IRAK1
MYD88
IRAK4
PIP4K2A
PPP2CA
PPP2CB
PPP2R1A
PPP2R1B
PPP2R5A
PPP2R5B
PPP2R5C
PPP2R5D
PPP2R5E
MAPK1
MAPK3
PTEN
TRAF6
PIP4K2C
PIP5K1A
PIP5K1B
PIP4K2B
IER3
IL33
IL1RL1
THEM4
PHLPP2
PHLPP1
TRIB3
CDKN1A
CDKN1B
CHUK
CREB1
FOXO1
FOXO3
MTOR
RICTOR
GSK3A
GSK3B
NR4A1
MDM2
FOXO4
PDPK1
PRR5
BAD
RPS6KB2
MLST8
TSC2
MAPKAP1
CASP9
AKT1S1
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network
for
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
SuperPath