PathCards :: RAF/MAP kinase cascade Pathway and related pathways

Pathway network for RAF/MAP kinase cascade SuperPath

4 Pathways in the RAF/MAP kinase cascade SuperPath

	RAF/MAP kinase cascade		MAPK1/MAPK3 signaling
	Diseases of signal transduction by growth factor receptors and second messengers		MAPK family signaling cascades

571 Genes in the RAF/MAP kinase cascade SuperPath

PSME3	PSMD14	CNKSR1	NRG3	FRS3	FRS2	DUSP10	PSMB11	PSMA8	CSK	NRG4	KLB
SPRED1	HBEGF	DUSP6	DUSP7	DUSP8	DUSP9	EGF	EGFR	SPRED2	ERBB2	ERBB3	ERBB4
EREG	FGA	FGB	FGF1	FGF2	FGF3	FGF4	FGF5	FGF6	FGF7	FGF8	FGF9
FGF10	FGFR1	FGFR3	FGFR2	FGFR4	FGG	MRAS	CNKSR2	PSME4	FLT3	FLT3LG	FN1
FYN	EPGN	FGF20	FGF22	KSR2	GRB2	HGF	NRG1	HRAS	IRS1	ITGA2B	ARAF
ITGB3	JAK2	AREG	KIT	KRAS	SPRED3	ARRB1	ARRB2	MARK3	MET	KITLG	MAP3K11
NF1	NRAS	PEBP1	PDGFA	PDGFB	PDGFRA	PDGFRB	PHB1	PIK3CA	PIK3CB	PIK3R1	PIK3R2
APBB1IP	PPP1CB	PPP1CC	PPP2CA	PPP2CB	PPP2R1A	PPP2R1B	PPP2R5A	PPP2R5B	PPP2R5C	PPP2R5D	PPP2R5E
MAPK1	MAPK3	MAP2K1	MAP2K2	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1
PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMB8	PSMB9	PSMB10	PSMC1	PSMC2	PSMC3
PSMC4	PSMC5	PSMC6	PSMD1	PSMD2	PSMD3	PSMD4	PSMD5	PSMD7	PSMD8	PSMD9	PSMD10
PSMD11	PSMD12	PSMD13	PSME1	PSME2	RAF1	RAP1A	RAP1B	BCL2L1	ACTB	RPS27A	SHC1
SOS1	SPTBN1	SRC	BRAF	BTC	TGFA	TLN1	ACTG1	UBA52	UBB	UBC	VCL
VWF	YWHAB	SEM1	CALM1	SHOC2	CALM2	FGF23	CALM3	DUSP16	CAMK2A	CAMK2B	CAMK2D
CAMK2G	BRAP	IRS2	FGF18	FGF17	FGF16	IQGAP1	KSR1	KL	PSMF1	NRG2	PSMD6
FGF19	RBX1	RANBP9	CHURC1-FNTB	RASGRP1	RASA4	LYPLA1	RASGRP4	CSF2	CSF2RA	CSF2RB	PAQR3
DAB2IP	DLG1	DLG2	DLG3	DLG4	DUSP1	DUSP2	DUSP4	DUSP5	RASGEF1A	RASA3	RGL1
FNTA	FNTB	ICMT	SHC2	RASGRP3	GDNF	GFRA1	GFRA2	GFRA3	LAT	ANGPT1	LAMTOR2
GRIN1	GRIN2B	GRIN2D	IL2	IL2RA	IL2RB	IL2RG	IL3	IL3RA	IL5	IL5RA	JAK1
JAK3	USP17L2	ARL2	NCAM1	NEFL	NRTN	ABHD17B	ZDHHC9	GOLGA7	SPTBN5	PDE6D	SHC3
IL17RD	PPP5C	PRKCQ	PRKG2	PSPN	RGL3	PTK2	SPTBN4	PTPN3	PTPN7	PTPRA	ABHD17C
RGL2	RALGDS	RASA1	RASA2	RASGRF1	RASGRF2	RET	MAPK12	GFRA4	RASAL3	SPTA1	SPTAN1
SPTB	SPTBN2	TEK	ABHD17A	KBTBD7	WDR83	RASAL1	CUL3	LAMTOR3	PEA15	ACTN2	SYNGAP1
ARTN	RASAL2	RAPGEF2	RCE1	PTPN11	IL6	IL6R	IL6ST	TYK2	CDK1	FOXO1	FOXO3
MYC	RAC1	AKT3	HDAC6	HDAC5	BCL2L11	MAMLD1	AKAP9	ADAM10	CDK8	CDKN1A	CDKN1B
TFG	CEBPB	ATG7	FAM114A2	OS9	TENT4A	CPSF6	CNTRL	CEP43	CDC37	ERLIN2	CHUK
CLCN6	PIK3AP1	CLTC	CREB1	CREBBP	AMER1	MIB2	CSNK1A1	CTBP1	CTBP2	CTNNB1	CUX1
DCTN1	JAG1	EEF1G	EP300	AKT1	AKT2	ESR1	ESR2	ETV6	FKBP1A	SEC31A	TRAK1
NCBP2	SNW1	DKK1	MPRIP	KANK1	NCSTN	HEY1	HEY2	ALK	MTOR	RICTOR	GAB1
FGFR1OP2	KAT2A	HEYL	SND1	DKK4	DKK2	ERLEC1	EML4	GOLGA4	GOLGB1	DLL1	GSK3A
GSK3B	GTF2F1	GTF2F2	ICOS	HDAC1	HDAC2	HIP1	NR4A1	APC	HES1	HSP90AA1	RBPJ
IHH	JAG2	JUNB	KDR	KIF5B	KLC1	HES5	RHOG	LCK	MYO18A	LMNA	LMO7
LRP6	LRP5	LYN	SMAD2	SMAD3	SMAD4	MDM2	MECP2	FOXO4	MSN	MYH9	NCBP1
ATIC	NOTCH1	NPM1	NOX4	DHH	TRAT1	DERL2	APH1A	BIN2	ZC3HC1	HDAC7	PDPK1
PIM1	PIK3CD	BCL11A	PLCG1	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G	POLR2H
POLR2I	POLR2J	POLR2K	POLR2L	NEURL1B	DLL4	ESRP1	RNF43	PPM1B	AGGF1	FBXW7	MAML3
PRR5	PRKAR1A	HHAT	AGK	PSENEN	HDAC8	ERBIN	PSEN1	PSEN2	ZC3HAV1	AGTRAP	BAD
PTEN	BIRC6	MIB1	WDR48	KIAA1549	RNF213	PTPN12	RAC2	RANBP2	BCL2A1	BCR	RPS6
RPS6KB2	RRBP1	SEL1L	MLST8	SHH	PORCN	SKP1	STAT1	STAT3	STAT5A	STAT5B	STRN
ADAM17	TBL1X	TCF7L2	TGFB1	TGFBR1	TGFBR2	TPM3	TPM4	TPR	TSC2	VAV1	VCP
YES1	ZMYM2	FZD5	MAPKAP1	KREMEN2	TBL1XR1	HDAC11	WDCP	TNKS2	KDM7A	FXR1	FIP1L1
AXIN1	FZD4	FZD6	FZD8	CARS1	APH1B	HDAC10	KREMEN1	CASP9	AKT1S1	MAML2	SYVN1
CUL1	PPFIBP1	PIK3R3	AP3B1	TNKS	CBL	TRIM24	HDAC3	KAT2B	SQSTM1	CCNC	WNT3A
PAPSS1	NEURL1	LRRFIP1	CD19	TRIP11	ZFYVE9	CD28	CD80	CD86	QKI	EIF2AK3	BAG4
NCOR1	NCOR2	GCC2	FAM131B	HDAC9	HDAC4	MAML1	GAB2	CDC42EP2	CDC42EP3	IGF2BP1	CDC42EP5
AGO3	AGO4	ETV4	TNRC6B	AGO1	AGO2	TNRC6A	HSPB1	DNAJB1	JUN	MOV10	PAK1
PAK2	PAK3	PRKACA	PRKACB	PRKACG	MAPK4	MAPK6	TNRC6C	RAG1	RAG2	XPO1	NCOA3
MAPKAPK5	CDC14B	CDC14A	CCND3	KALRN	SEPTIN7	CDC42

*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.

STRING interaction network for RAF/MAP kinase cascade SuperPath