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Resolution of D-loop Structures through Holliday Junction Intermediates
SuperPath
Pathway network
for
Resolution of D-loop Structures through Holliday Junction Intermediates
SuperPath
8
Pathways
in the
Resolution of D-loop Structures through Holliday Junction Intermediates
SuperPath
Impaired BRCA2 binding to PALB2
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
Resolution of D-Loop Structures
Defective homologous recombination repair (HRR) due to PALB2 loss of function
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function
Resolution of D-loop Structures through Holliday Junction Intermediates
Defective homologous recombination repair (HRR) due to BRCA1 loss of function
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
35
Genes
in the
Resolution of D-loop Structures through Holliday Junction Intermediates
SuperPath
RAD50
KAT5
RAD51AP1
RMI2
DNA2
MRE11
NBN
ATM
BARD1
RAD51
RAD51C
RAD51B
RAD51D
RBBP8
BLM
BRCA1
BRCA2
TOP3A
WRN
XRCC2
PALB2
RMI1
BRIP1
EXO1
SEM1
XRCC3
EME1
EME2
SPIDR
GEN1
RTEL1
SLX1A
SLX1B
MUS81
SLX4
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network
for
Resolution of D-loop Structures through Holliday Junction Intermediates
SuperPath