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Signaling by ALK in cancer
SuperPath
Pathway network
for
Signaling by ALK in cancer
SuperPath
4
Pathways
in the
Signaling by ALK in cancer
SuperPath
Nuclear events stimulated by ALK signaling in cancer
ALK mutants bind TKIs
Signaling by ALK in cancer
Signaling by ALK fusions and activated point mutants
55
Genes
in the
Signaling by ALK in cancer
SuperPath
CLTC
FN1
ALK
EML4
NPM1
CEBPB
JUNB
KIF5B
MECP2
ZC3HC1
MAPK1
MAPK3
BCL2A1
RPS6
SKP1
STAT3
STAT5A
CUL1
RBX1
HIP1
BCL11A
PPM1B
PRKAR1A
BIRC6
STRN
EIF2AK3
TFG
FRS3
FRS2
DCTN1
EEF1G
SEC31A
GRB2
IRS1
KLC1
LMO7
MSN
MYH9
ATIC
PIK3CA
PIK3R1
PLCG1
RNF213
RANBP2
RRBP1
SHC1
TPM3
TPM4
TPR
VCL
WDCP
CARS1
PPFIBP1
SQSTM1
GCC2
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network
for
Signaling by ALK in cancer
SuperPath