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Transcriptional Regulation by MECP2
SuperPath
Pathway network
for
Transcriptional Regulation by MECP2
SuperPath
18
Pathways
in the
Transcriptional Regulation by MECP2
SuperPath
Post-transcriptional silencing by small RNAs
MECP2 regulates neuronal receptors and channels
Loss of phosphorylation of MECP2 at T308
PTEN Loss of Function in Cancer
Loss of function of MECP2 in Rett syndrome
Loss of MECP2 binding ability to the NCoR/SMRT complex
Transcriptional Regulation by MECP2
Competing endogenous RNAs (ceRNAs) regulate PTEN translation
Loss of MECP2 binding ability to 5hmC-DNA
Loss of MECP2 binding ability to 5mC-DNA
Regulation of PTEN mRNA translation
Disorders of Developmental Biology
MECP2 regulates transcription factors
MECP2 regulates transcription of genes involved in GABA signaling
MECP2 regulates transcription of neuronal ligands
Regulation of MECP2 expression and activity
Pervasive developmental disorders
Disorders of Nervous System Development
62
Genes
in the
Transcriptional Regulation by MECP2
SuperPath
MECP2
SIN3A
HDAC1
PRKACA
CALM1
CALM2
CALM3
CAMK4
GPS2
TBL1X
TBL1XR1
HDAC3
NCOR1
NCOR2
AGO3
AGO4
TNRC6B
AGO1
AGO2
TNRC6A
TNRC6C
CREB1
MOV10
HDAC2
PTEN
GPRIN1
FKBP5
GRIA2
GRIN2A
GRIN2B
MET
OPRK1
OPRM1
PTPN1
PTPN4
SLC2A3
TRPC3
CRH
FOXG1
GAD1
GAD2
DLL1
HIPK2
HTT
LBR
MEF2C
PPARG
RBFOX1
BDNF
SST
CAMK2A
CAMK2B
CAMK2D
CAMK2G
AURKB
GAMT
IRAK1
MOBP
DGCR8
PVALB
SGK1
SOX2
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network
for
Transcriptional Regulation by MECP2
SuperPath