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Unfolded Protein Response (UPR)
SuperPath
Pathway network
for
Unfolded Protein Response (UPR)
SuperPath
7
Pathways
in the
Unfolded Protein Response (UPR)
SuperPath
ATF6 (ATF6-alpha) activates chaperones
CREB3 factors activate genes
ATF6 (ATF6-alpha) activates chaperone genes
Unfolded Protein Response (UPR)
ATF6B (ATF6-beta) activates chaperones
XBP1(S) activates chaperone genes
IRE1alpha activates chaperones
94
Genes
in the
Unfolded Protein Response (UPR)
SuperPath
HSPA5
XBP1
MBTPS2
MBTPS1
DDIT3
ATF6
ATF4
NFYA
NFYB
NFYC
HSP90B1
CALR
PLA2G4B
CTDSP2
PREB
PDIA6
HYOU1
YIF1A
PDIA5
KDELR3
KLHDC3
ADD1
TPP1
DCTN1
DDX11
EXTL1
EXTL2
EXTL3
SEC31A
GFPT1
SERP1
GSK3A
HDGF
CXXC1
ACADVL
LMNA
DNAJB9
SULT1A4
DNAJB11
FKBP14
WIPI1
PPP2R5B
ARFGAP1
MYDGF
DNAJC3
SRPRB
TSPYL2
SHC1
SRPRA
SSR1
SULT1A3
TLN1
WFS1
ZBTB17
SYVN1
JMJD7-PLA2G4B
ATP6V0D1
GOSR2
EDEM1
TATDN2
CUL7
CREB3
CREB3L4
CREBRF
CREB3L2
DCSTAMP
CREB3L3
CREB3L1
ERN1
CEBPB
CEBPG
EXOSC8
EXOSC6
DCP2
EIF2S1
EIF2S3
DIS3
EXOSC7
EXOSC2
IGFBP1
CXCL8
ASNS
ATF3
PARN
EXOSC3
EXOSC1
EXOSC9
EXOSC4
EXOSC5
CCL2
KHSRP
EIF2S2
EIF2AK3
HERPUD1
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network
for
Unfolded Protein Response (UPR)
SuperPath
