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207 search results for Insulin
# SuperPathway Name Genes Count Relevance Score
1 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 125 2.565
SuperPathway
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 2
  • Insulin Like Growth Factor Binding Protein Acid Labile Subunit
  • Insulin Like Growth Factor Binding Protein 1
  • Insulin Like Growth Factor Binding Protein 2
  • Insulin Like Growth Factor Binding Protein 3
  • Insulin Like Growth Factor Binding Protein 4
  • Insulin Like Growth Factor Binding Protein 5
  • Insulin Like Growth Factor Binding Protein 6
  • Insulin Like Growth Factor Binding Protein 7
Pathways
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
2 Insulin receptor signalling cascade 87 2.447
SuperPathway
  • Insulin receptor signalling cascade
Genes names
  • Insulin Degrading Enzyme
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
  • Insulin Receptor Substrate 4
Pathways
  • Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
  • Signaling by Insulin receptor
  • Insulin receptor signalling cascade
3 Translation Insulin regulation of translation 183 2.221
SuperPathway
  • Translation Insulin regulation of translation
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor Binding Protein 3
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
  • Insulin Receptor Substrate 4
Pathways
  • Translation Insulin regulation of translation
  • Regulation of lipid metabolism Insulin signaling-generic cascades
4 Leptin-insulin signaling overlap 21 1.814
SuperPathway
  • Leptin-insulin signaling overlap
Genes names
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
  • Insulin Receptor Substrate 4
Pathways
  • Leptin-insulin signaling overlap
5 Insulin signaling in adipocytes (normal condition) 8 1.787
SuperPathway
  • Insulin signaling in adipocytes (normal condition)
Genes names
  • Insulin Receptor
  • Insulin Receptor Substrate 1
Pathways
  • Insulin signaling in adipocytes (diabetic condition)
  • Insulin signaling in adipocytes (normal condition)
6 Roles of ceramides in development of insulin resistance 22 1.741
SuperPathway
  • Roles of ceramides in development of insulin resistance
Genes names
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
Pathways
  • Roles of ceramides in development of insulin resistance
7 Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling 36 1.741
SuperPathway
  • Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor Binding Protein 5
  • Insulin Receptor Substrate 1
Pathways
  • Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling
8 Insulin receptor recycling 77 1.659
SuperPathway
  • Insulin receptor recycling
Genes names
  • Insulin Degrading Enzyme
  • Insulin
  • Insulin Receptor
Pathways
  • Insulin receptor recycling
9 Insulin Pathway 44 1.659
SuperPathway
  • Insulin Pathway
Genes names
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
Pathways
  • Insulin Pathway
10 Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA 3 1.659
SuperPathway
  • Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA
Genes names
  • Insulin Like Growth Factor 2 MRNA Binding Protein 1
  • Insulin Like Growth Factor 2 MRNA Binding Protein 2
  • Insulin Like Growth Factor 2 MRNA Binding Protein 3
Pathways
  • Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA
11 Integration of energy metabolism 108 1.642
Genes names
  • Insulin
Pathways
  • Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
  • Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
  • Acetylcholine regulates insulin secretion
  • Intracellular metabolism of fatty acids regulates insulin secretion
  • Free fatty acids regulate insulin secretion
  • Regulation of insulin secretion
12 Insulin-mediated glucose transport 19 1.562
SuperPathway
  • Insulin-mediated glucose transport
Genes names
  • Insulin
  • Insulin Receptor
Pathways
  • Insulin-mediated glucose transport
13 Beta-Adrenergic Signaling 333 1.522
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2 Receptor
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
Pathways
  • Insulin Receptor Pathway
  • Insulin Pathway
14 Insulin processing 25 1.435
SuperPathway
  • Insulin processing
Genes names
  • Insulin
Pathways
  • Insulin processing
15 Angiopoietin-like protein 8 regulatory pathway 194 1.231
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
  • Insulin Receptor Substrate 4
Pathways
  • Insulin signaling
16 IL-9 Signaling Pathways 169 1.158
Genes names
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
Pathways
  • Adipocytokines and Insulin Signaling
17 Metabolism of proteins 1970 1.062
Genes names
  • Insulin Degrading Enzyme
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 2
  • Insulin Like Growth Factor Binding Protein Acid Labile Subunit
  • Insulin Like Growth Factor Binding Protein 1
  • Insulin Like Growth Factor Binding Protein 2
  • Insulin Like Growth Factor Binding Protein 3
  • Insulin Like Growth Factor Binding Protein 4
  • Insulin Like Growth Factor Binding Protein 5
  • Insulin Like Growth Factor Binding Protein 6
  • Insulin Like Growth Factor Binding Protein 7
  • Insulin
18 Signal Transduction 2590 1.062
Genes names
  • Insulin Degrading Enzyme
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Like Growth Factor 2 MRNA Binding Protein 1
  • Insulin
  • Insulin Like 3
  • Insulin Like 5
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
  • Insulin Receptor Substrate 4
19 Development IGF-1 receptor signaling 110 1.017
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Like Growth Factor Binding Protein 1
  • Insulin Like Growth Factor Binding Protein 2
  • Insulin Like Growth Factor Binding Protein 3
  • Insulin Like Growth Factor Binding Protein 4
  • Insulin Like Growth Factor Binding Protein 5
  • Insulin Like Growth Factor Binding Protein 6
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
20 Glucose / Energy Metabolism 307 0.970
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2 Receptor
  • Insulin Like Growth Factor Binding Protein 1
  • Insulin Like Growth Factor Binding Protein 2
  • Insulin Like Growth Factor Binding Protein 3
  • Insulin Like Growth Factor Binding Protein 7
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
21 Signaling by Receptor Tyrosine Kinases 524 0.920
Genes names
  • Insulin Degrading Enzyme
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
  • Insulin Receptor Substrate 4
22 ERK Signaling 1185 0.920
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Like Growth Factor 2 Receptor
  • Insulin Receptor
  • Insulin Receptor Related Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
  • Insulin Receptor Substrate 4
23 TGF-Beta Pathway 653 0.920
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Related Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
  • Insulin Receptor Substrate 4
24 PI3K-Akt signaling pathway 390 0.867
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
  • Insulin Receptor Substrate 4
25 p70S6K Signaling 392 0.811
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Like Growth Factor 2 Receptor
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
26 NFAT and Cardiac Hypertrophy 326 0.811
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
  • Insulin Receptor Substrate 4
27 Apoptotic Pathways in Synovial Fibroblasts 731 0.811
Genes names
  • Insulin Degrading Enzyme
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Like Growth Factor 2 Receptor
  • Insulin
  • Insulin Receptor
28 CREB Pathway 529 0.751
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Like Growth Factor 2 Receptor
  • Insulin Receptor
  • Insulin Receptor Related Receptor
29 Alzheimer's disease and miRNA effects 267 0.751
Genes names
  • Insulin Degrading Enzyme
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
  • Insulin Receptor Substrate 4
30 Akt Signaling 682 0.751
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Receptor
  • Insulin Receptor Related Receptor
  • Insulin Receptor Substrate 1
31 Adipogenesis 131 0.751
Genes names
  • Insulin Like Growth Factor 1
  • Insulin
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
  • Insulin Receptor Substrate 3, Pseudogene
  • Insulin Receptor Substrate 4
32 GPCR Pathway 712 0.751
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Like Growth Factor 2 Receptor
  • Insulin Receptor
  • Insulin Receptor Related Receptor
33 Myometrial relaxation and contraction pathways 215 0.751
Genes names
  • Insulin Like Growth Factor Binding Protein 1
  • Insulin Like Growth Factor Binding Protein 2
  • Insulin Like Growth Factor Binding Protein 3
  • Insulin Like Growth Factor Binding Protein 4
  • Insulin Like Growth Factor Binding Protein 5
  • Insulin Like Growth Factor Binding Protein 6
34 Senescence and autophagy in cancer 105 0.751
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor Binding Protein 3
  • Insulin Like Growth Factor Binding Protein 5
  • Insulin Like Growth Factor Binding Protein 7
  • Insulin
35 Activation of cAMP-Dependent PKA 632 0.751
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Like Growth Factor 2 Receptor
  • Insulin Receptor
  • Insulin Receptor Related Receptor
36 mTOR Signaling 139 0.686
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2 Receptor
  • Insulin Receptor
  • Insulin Receptor Related Receptor
  • Insulin Receptor Substrate 1
37 Nanog in Mammalian ESC Pluripotency 534 0.686
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Receptor
  • Insulin Receptor Related Receptor
38 Prolactin Signaling 432 0.686
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
39 Malignant pleural mesothelioma 409 0.686
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin
  • Insulin Receptor
40 Actin Nucleation by ARP-WASP Complex 344 0.686
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Receptor
  • Insulin Receptor Related Receptor
41 PIP3 activates AKT signaling 310 0.613
Genes names
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
42 MAPK Signaling: Mitogens 108 0.613
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2 Receptor
  • Insulin Receptor
  • Insulin Receptor Related Receptor
43 PAK Pathway 686 0.613
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Like Growth Factor 2 Receptor
44 Nonalcoholic fatty liver disease 46 0.613
Genes names
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
45 MIF Mediated Glucocorticoid Regulation 681 0.613
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Related Receptor
46 Cell adhesion_ECM remodeling 61 0.613
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Like Growth Factor Binding Protein 4
47 Tyrosine Kinases / Adaptors 148 0.613
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2 Receptor
  • Insulin Receptor
  • Insulin Receptor Substrate 1
48 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 135 0.613
Genes names
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
49 AMPK Enzyme Complex Pathway 153 0.613
Genes names
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
50 Phospholipase-C Pathway 503 0.613
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Like Growth Factor 2 Receptor
51 Anti-diabetic Drug Potassium Channel Inhibitors Pathway, Pharmacodynamics 28 0.613
Genes names
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
52 Development Ligand-independent activation of ESR1 and ESR2 135 0.613
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Receptor
  • Insulin Receptor Substrate 1
53 Immune response Function of MEF2 in T lymphocytes 124 0.613
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
  • Insulin Receptor Substrate 1
54 Thromboxane signalling through TP receptor 96 0.545
Pathways
  • Adrenaline,noradrenaline inhibits insulin secretion
55 Pentose phosphate pathway 15 0.545
Pathways
  • Insulin effects increased synthesis of Xylulose-5-Phosphate
56 Gene expression (Transcription) 1546 0.531
Genes names
  • Insulin Like Growth Factor Binding Protein 1
  • Insulin Like Growth Factor Binding Protein 3
  • Insulin
57 Endochondral ossification with skeletal dysplasias 63 0.531
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
58 Autophagy pathway 228 0.531
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin
  • Insulin Receptor
59 Cardiac progenitor differentiation 53 0.531
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 2
  • Insulin
60 Mesenchymal Stem Cells and Lineage-specific Markers 95 0.531
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor Binding Protein 3
  • Insulin
61 IGF1 pathway 29 0.531
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
62 Apoptosis and survival FAS signaling cascades 108 0.531
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Receptor Substrate 1
63 Transcription factor regulation in adipogenesis 22 0.531
Genes names
  • Insulin Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
64 Endometrial cancer 201 0.531
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Receptor Substrate 1
65 Vitamin D receptor pathway 185 0.531
Genes names
  • Insulin Like Growth Factor Binding Protein 1
  • Insulin Like Growth Factor Binding Protein 3
  • Insulin Like Growth Factor Binding Protein 5
66 Metabolism of steroids 194 0.531
Genes names
  • Insulin
  • Insulin Induced Gene 1
  • Insulin Induced Gene 2
67 Neuroinflammation and glutamatergic signaling 140 0.531
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Receptor
  • Insulin Receptor Substrate 1
68 mTOR Pathway 58 0.531
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2 Receptor
  • Insulin Receptor
69 TNFR1 Pathway 190 0.531
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
70 Apoptosis and survival BAD phosphorylation 112 0.531
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Receptor Substrate 1
71 Photodynamic therapy-induced HIF-1 survival signaling 37 0.531
Genes names
  • Insulin Like Growth Factor Binding Protein 1
  • Insulin Like Growth Factor Binding Protein 2
  • Insulin Like Growth Factor Binding Protein 3
72 Processing of Capped Intron-Containing Pre-mRNA 745 0.531
Genes names
  • Insulin Like Growth Factor 2 MRNA Binding Protein 1
  • Insulin Like Growth Factor 2 MRNA Binding Protein 2
  • Insulin Like Growth Factor 2 MRNA Binding Protein 3
73 NF-kappaB Pathway 152 0.531
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2 Receptor
  • Insulin Receptor
74 Metabolism 2121 0.531
Genes names
  • Insulin
  • Insulin Induced Gene 1
  • Insulin Induced Gene 2
75 MECP2 and associated Rett syndrome 73 0.531
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
76 Signaling events mediated by PTP1B 46 0.531
Genes names
  • Insulin
  • Insulin Receptor
  • Insulin Receptor Substrate 1
77 Hepatic ABC Transporters 88 0.531
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin
  • Insulin Receptor
78 RAF/MAP kinase cascade 571 0.531
Genes names
  • Insulin Like Growth Factor 2 MRNA Binding Protein 1
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
79 Innate Immune System 2025 0.531
Genes names
  • Insulin Like Growth Factor 2 Receptor
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
80 Transcription Androgen Receptor nuclear signaling 98 0.531
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Receptor Substrate 1
81 Development_Leptin signaling via PI3K-dependent pathway 52 0.434
Genes names
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
82 AMP-activated protein kinase signaling 100 0.434
Genes names
  • Insulin
  • Insulin Receptor
83 Hippo-Merlin signaling dysregulation 60 0.434
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Receptor
84 Interleukin-7 signaling 36 0.434
Genes names
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
85 G-protein signaling_RhoA regulation pathway 49 0.434
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
86 Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers 133 0.434
Genes names
  • Insulin Like Growth Factor 1
  • Insulin
87 FOXA2 pathway 20 0.434
Genes names
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
88 Breast cancer pathway 199 0.434
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
89 SHP2 signaling 54 0.434
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Receptor Substrate 1
90 Relaxin receptors 8 0.434
Genes names
  • Insulin Like 3
  • Insulin Like 5
91 IL4-mediated signaling events 60 0.434
Genes names
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
92 Signaling events mediated by TCPTP 39 0.434
Genes names
  • Insulin
  • Insulin Receptor
93 Peptide hormone metabolism 89 0.434
Genes names
  • Insulin Like Growth Factor 1
  • Insulin
94 Nuclear receptors meta-pathway 315 0.434
Genes names
  • Insulin Like Growth Factor Binding Protein 1
  • Insulin Receptor Substrate 2
95 Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics 20 0.434
Genes names
  • Insulin
  • Insulin Induced Gene 2
96 Cellular responses to stimuli 802 0.434
Genes names
  • Insulin Like Growth Factor Binding Protein 1
  • Insulin Like Growth Factor Binding Protein 7
97 fMLP Pathway 266 0.434
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
98 Chks in Checkpoint Regulation 186 0.434
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Induced Gene 1
99 NF-KappaB Family Pathway 242 0.434
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 2
100 Vesicle-mediated transport 673 0.434
Genes names
  • Insulin Like Growth Factor 2 Receptor
  • Insulin
101 FOXA2 and FOXA3 transcription factor networks 40 0.434
Genes names
  • Insulin Like Growth Factor Binding Protein 1
  • Insulin
102 Transcription_Transcription factor Tubby signaling pathways 26 0.434
Genes names
  • Insulin
  • Insulin Receptor
103 DNA damage response (only ATM dependent) 101 0.434
Genes names
  • Insulin Receptor
  • Insulin Receptor Substrate 1
104 MicroRNAs in cardiomyocyte hypertrophy 112 0.434
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
105 Growth hormone receptor signaling 29 0.434
Genes names
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
106 GDNF-Family Ligands and Receptor Interactions 100 0.434
Genes names
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
107 Integrins in angiogenesis 57 0.434
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Receptor Substrate 1
108 Translational Control 190 0.434
Genes names
  • Insulin Like Growth Factor 2 MRNA Binding Protein 1
  • Insulin Like Growth Factor 2 MRNA Binding Protein 2
109 FOXO-mediated transcription 65 0.434
Genes names
  • Insulin Like Growth Factor Binding Protein 1
  • Insulin
110 Signaling by NTRKs 134 0.434
Genes names
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
111 Development EPO-induced Jak-STAT pathway 75 0.434
Genes names
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
112 Posttranslational regulation of adherens junction stability and dissassembly 48 0.434
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Like Growth Factor 2
113 Response to elevated platelet cytosolic Ca2+ 621 0.434
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 2
114 RET signaling 55 0.434
Genes names
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
115 Cytokine Signaling in Immune system 732 0.434
Genes names
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
116 Interferon Pathway 91 0.434
Genes names
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
117 GPCR downstream signalling 710 0.434
Genes names
  • Insulin Like 3
  • Insulin Like 5
118 Class A/1 (Rhodopsin-like receptors) 556 0.434
Genes names
  • Insulin Like 3
  • Insulin Like 5
119 Nervous system development 1168 0.434
Genes names
  • Insulin
  • Insulin Receptor Substrate 2
120 Alzheimers Disease Pathway 45 0.434
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Receptor
121 Focal adhesion 197 0.434
Genes names
  • Insulin Like Growth Factor 1
  • Insulin Like Growth Factor 1 Receptor
122 Development EGFR signaling via small GTPases 70 0.434
Genes names
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
123 Type II diabetes mellitus 22 0.434
Genes names
  • Insulin Receptor
  • Insulin Receptor Substrate 1
124 Autophagy 63 0.434
Genes names
  • Insulin
  • Insulin Receptor
125 Infectious disease 1747 0.434
Genes names
  • Insulin Receptor Substrate 1
  • Insulin Receptor Substrate 2
126 Pluripotent stem cell differentiation pathway 48 0.434
Genes names
  • Insulin Like Growth Factor 1
  • Insulin
127 Ras signaling 183 0.434
Genes names
  • Insulin Like Growth Factor 1 Receptor
  • Insulin Receptor
128 Neural Stem Cells and Lineage-specific Markers 79 0.307
Genes names
  • Insulin Like Growth Factor 1
129 Pathways affected in adenoid cystic carcinoma 62 0.307
Genes names
  • Insulin Receptor Related Receptor
130 Signaling by Erythropoietin 40 0.307
Genes names
  • Insulin Receptor Substrate 2
131 16p11.2 proximal deletion syndrome 72 0.307
Genes names
  • Insulin Like Growth Factor Binding Protein 3
132 Presynaptic function of Kainate receptors 118 0.307
Genes names
  • Insulin Receptor
133 Gastrin signaling pathway 112 0.307
Genes names
  • Insulin Receptor Substrate 1
134 IL2 signaling events mediated by STAT5 74 0.307
Genes names
  • Insulin Receptor Substrate 1
135 Interactions between LOXL4 and oxidative stress pathway 18 0.307
Genes names
  • Insulin Like Growth Factor Binding Protein 7
136 Cori cycle 17 0.307
Genes names
  • Insulin
137 Metformin Pathway, Pharmacodynamics 36 0.307
Genes names
  • Insulin Receptor Substrate 1
138 16p11.2 distal deletion syndrome 31 0.307
Genes names
  • Insulin Receptor
139 Arf6 trafficking events 47 0.307
Genes names
  • Insulin
140 Mammalian disorder of sexual development 25 0.307
Genes names
  • Insulin Like 3
141 Farnesoid X receptor pathway 19 0.307
Genes names
  • Insulin Receptor Substrate 2
142 A-beta Uptake and Degradation 32 0.307
Genes names
  • Insulin Degrading Enzyme
143 Transcription_Role of VDR in regulation of genes involved in osteoporosis 45 0.307
Genes names
  • Insulin Like Growth Factor 1
144 Validated transcriptional targets of deltaNp63 isoforms 47 0.307
Genes names
  • Insulin Like Growth Factor Binding Protein 3
145 Transcriptional Regulation by NPAS4 34 0.307
Genes names
  • Insulin
146 Peroxisomal lipid metabolism 167 0.307
Genes names
  • Insulin Degrading Enzyme
147 White fat cell differentiation 33 0.307
Genes names
  • Insulin
148 MAPK-Erk Pathway 275 0.307
Genes names
  • Insulin Like Growth Factor 2 MRNA Binding Protein 2
149 Regulation of TP53 Activity 362 0.307
Genes names
  • Insulin Like Growth Factor Binding Protein 3
150 PERK regulates gene expression 32 0.307
Genes names
  • Insulin Like Growth Factor Binding Protein 1
151 Deubiquitination 298 0.307
Genes names
  • Insulin Degrading Enzyme
152 FOXA1 transcription factor network 37 0.307
Genes names
  • Insulin
153 trans-Golgi Network Vesicle Budding 72 0.307
Genes names
  • Insulin Like Growth Factor 2 Receptor
154 Hormonal control of pubertal growth spurt 5 0.307
Genes names
  • Insulin Like Growth Factor 1
155 Celecoxib Pathway, Pharmacodynamics 58 0.307
Genes names
  • Insulin Like Growth Factor Binding Protein 3
156 Somatroph axis (GH) and its relationship to dietary restriction and aging 5 0.307
Genes names
  • Insulin Like Growth Factor 1 Receptor
157 Development Dopamine D2 receptor transactivation of EGFR 128 0.307
Genes names
  • Insulin Like Growth Factor 1 Receptor
158 S1P2 pathway 16 0.307
Genes names
  • Insulin Receptor Substrate 1
159 Primary ovarian insufficiency 170 0.307
Genes names
  • Insulin Like 3
160 Caloric restriction and aging 9 0.307
Genes names
  • Insulin Like Growth Factor 1
161 Thyroid stimulating hormone (TSH) signaling pathway 58 0.307
Genes names
  • Insulin Like Growth Factor 1 Receptor
162 Immune response IL-23 signaling pathway 160 0.307
Genes names
  • Insulin Receptor Substrate 2
163 Oxysterols derived from cholesterol 36 0.307
Genes names
  • Insulin Induced Gene 1
164 Validated transcriptional targets of TAp63 isoforms 54 0.307
Genes names
  • Insulin Like Growth Factor Binding Protein 3
165 Hematopoietic Stem Cells and Lineage-specific Markers 116 0.307
Genes names
  • Insulin Like Growth Factor Binding Protein 2
166 Cytoskeletal Signaling 308 0.307
Genes names
  • Insulin Like Growth Factor 2 MRNA Binding Protein 1
167 Apoptosis and survival_Regulation of Apoptosis by Mitochondrial Proteins 33 0.307
Genes names
  • Insulin Like Growth Factor 1 Receptor
168 eIF5A regulation in response to inhibition of the nuclear export system 4 0.307
Genes names
  • Insulin Like Growth Factor 2 MRNA Binding Protein 1
169 Regulation of nuclear beta catenin signaling and target gene transcription 72 0.307
Genes names
  • Insulin Like Growth Factor 2 MRNA Binding Protein 1
170 Lung fibrosis 63 0.307
Genes names
  • Insulin Like Growth Factor 1
171 Cellular Senescence 196 0.307
Genes names
  • Insulin Like Growth Factor Binding Protein 7
172 Transport to the Golgi and subsequent modification 304 0.307
Genes names
  • Insulin
173 Golgi-to-ER retrograde transport 369 0.307
Genes names
  • Insulin Like Growth Factor 2 Receptor
174 A-beta Plaque Formation and APP Metabolism 23 0.307
Genes names
  • Insulin Degrading Enzyme
175 Clathrin-mediated endocytosis 146 0.307
Genes names
  • Insulin Like Growth Factor 2 Receptor
176 Unfolded Protein Response (UPR) 94 0.307
Genes names
  • Insulin Like Growth Factor Binding Protein 1
177 Wnt Pathway 63 0.307
Genes names
  • Insulin Like Growth Factor Binding Protein 4
178 Integrated breast cancer pathway 150 0.307
Genes names
  • Insulin Receptor Substrate 1
179 TP53 Regulates Transcription of Cell Death Genes 44 0.307
Genes names
  • Insulin Like Growth Factor Binding Protein 3
180 Plasma membrane estrogen receptor signaling 24 0.307
Genes names
  • Insulin Like Growth Factor 1 Receptor
181 Ebola virus infection in host 129 0.307
Genes names
  • Insulin Like Growth Factor 1 Receptor
182 Direct p53 effectors 128 0.307
Genes names
  • Insulin Like Growth Factor Binding Protein 3
183 Regulation of beta-cell development 41 0.307
Genes names
  • Insulin
184 Chromatin Regulation / Acetylation 255 0.307
Genes names
  • Insulin Like Growth Factor 2 MRNA Binding Protein 3
185 Prostaglandin and leukotriene metabolism in senescence 27 0.307
Genes names
  • Insulin Like Growth Factor Binding Protein 5
186 Head and neck squamous cell carcinoma 73 0.307
Genes names
  • Insulin Like Growth Factor 1 Receptor
187 Wnt / Hedgehog / Notch 182 0.307
Genes names
  • Insulin Like Growth Factor 2 MRNA Binding Protein 1
188 HIF-1-alpha transcription factor network 65 0.307
Genes names
  • Insulin Like Growth Factor Binding Protein 1
189 Congenital generalized lipodystrophy 17 0.307
Genes names
  • Insulin Receptor Substrate 1
190 Clock-controlled autophagy in bone metabolism 80 0.307
Genes names
  • Insulin Like Growth Factor 1
191 Jak-Stat Signaling Pathway 88 0.307
Genes names
  • Insulin Like Growth Factor 1 Receptor
192 ATF-2 transcription factor network 57 0.307
Genes names
  • Insulin
193 Prader-Willi and Angelman syndrome 60 0.307
Genes names
  • Insulin
194 Stabilization and expansion of the E-cadherin adherens junction 42 0.307
Genes names
  • Insulin Like Growth Factor 1 Receptor
195 Genes targeted by miRNAs in adipocytes 13 0.307
Genes names
  • Insulin Like Growth Factor 1
196 Regulation of activated PAK-2p34 by proteasome mediated degradation 978 0.307
Genes names
  • Insulin Like Growth Factor 2 MRNA Binding Protein 1
197 Extracellular vesicles in the crosstalk of cardiac cells 22 0.307
Genes names
  • Insulin Like Growth Factor 1
198 Oligodendrocyte specification and differentiation, leading to myelin components for CNS 28 0.307
Genes names
  • Insulin Like Growth Factor 1
199 Hair follicle development: cytodifferentiation - part 3 of 3 54 0.307
Genes names
  • Insulin Like Growth Factor 1
200 ESR-mediated signaling 298 0.307
Genes names
  • Insulin Like Growth Factor 1 Receptor
201 Signaling by ALK in cancer 55 0.307
Genes names
  • Insulin Receptor Substrate 1
202 Retrograde transport at the Trans-Golgi-Network 49 0.307
Genes names
  • Insulin Like Growth Factor 2 Receptor
203 G alpha (s) signalling events 158 0.307
Genes names
  • Insulin Like 3
204 NRF2-ARE regulation 23 0.307
Genes names
  • Insulin Receptor
205 Signaling by ALK 27 0.307
Genes names
  • Insulin Receptor Substrate 1
206 RNA Polymerase I Promoter Opening 509 0.307
Genes names
  • Insulin
207 mTOR signaling pathway 48 0.307
Genes names
  • Insulin Receptor Substrate 1