1 |
|
Prostaglandin synthesis and regulation
|
56 |
2.897 |
SuperPathway |
- Prostaglandin synthesis and regulation
|
Genes names |
- Hematopoietic Prostaglandin D Synthase
- Prostaglandin D2 Receptor
- Prostaglandin D2 Receptor 2
- Prostaglandin D2 Synthase
- Prostaglandin E Receptor 1
- Prostaglandin E Receptor 2
- Prostaglandin E Receptor 3
- Prostaglandin E Receptor 4
- Prostaglandin E Synthase
- Prostaglandin E Synthase 2
- Prostaglandin E Synthase 3
- Prostaglandin F Receptor
- Prostaglandin F2 Receptor Inhibitor
- Prostaglandin I2 Receptor
- Prostaglandin I2 Synthase
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
Pathways |
- Prostaglandin synthesis and regulation
|
|
2 |
|
Prostaglandin and leukotriene metabolism in senescence
|
27 |
2.473 |
SuperPathway |
- Prostaglandin and leukotriene metabolism in senescence
|
Genes names |
- Prostaglandin D2 Synthase
- Prostaglandin E Receptor 1
- Prostaglandin E Receptor 2
- Prostaglandin E Receptor 3
- Prostaglandin E Receptor 4
- Prostaglandin E Synthase
- Prostaglandin I2 Synthase
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
Pathways |
- Prostaglandin and leukotriene metabolism in senescence
|
|
3 |
|
Prostaglandin 2 biosynthesis and metabolism FM
|
23 |
2.408 |
SuperPathway |
- Prostaglandin 2 biosynthesis and metabolism FM
|
Genes names |
- Hematopoietic Prostaglandin D Synthase
- Prostaglandin D2 Synthase
- Prostaglandin E Synthase
- Prostaglandin E Synthase 2
- Prostaglandin I2 Synthase
- Prostaglandin Reductase 1
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
Pathways |
- Prostaglandin 2 biosynthesis and metabolism FM
|
|
4 |
|
Prostaglandin signaling
|
28 |
1.873 |
SuperPathway |
|
Genes names |
- Prostaglandin E Receptor 2
- Prostaglandin E Synthase
|
Pathways |
|
|
5 |
|
Fatty acid metabolism
|
179 |
1.855 |
Genes names |
- Hematopoietic Prostaglandin D Synthase
- Prostaglandin D2 Synthase
- Prostaglandin E Synthase
- Prostaglandin E Synthase 2
- Prostaglandin E Synthase 3
- Prostaglandin I2 Synthase
- Prostaglandin Reductase 1
- Prostaglandin Reductase 2
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
Pathways |
- Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
|
|
6 |
|
Celecoxib Pathway, Pharmacodynamics
|
58 |
1.309 |
Genes names |
- Hematopoietic Prostaglandin D Synthase
- Prostaglandin D2 Receptor
- Prostaglandin E Receptor 1
- Prostaglandin E Receptor 2
- Prostaglandin E Receptor 3
- Prostaglandin E Receptor 4
- Prostaglandin E Synthase
- Prostaglandin F Receptor
- Prostaglandin I2 Receptor
- Prostaglandin I2 Synthase
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
|
7 |
|
Metabolism
|
2121 |
1.195 |
Genes names |
- Hematopoietic Prostaglandin D Synthase
- Prostaglandin D2 Synthase
- Prostaglandin E Synthase
- Prostaglandin E Synthase 2
- Prostaglandin E Synthase 3
- Prostaglandin I2 Synthase
- Prostaglandin Reductase 1
- Prostaglandin Reductase 2
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
|
8 |
|
Signal Transduction
|
2590 |
1.134 |
Genes names |
- Prostaglandin D2 Receptor
- Prostaglandin D2 Receptor 2
- Prostaglandin E Receptor 1
- Prostaglandin E Receptor 2
- Prostaglandin E Receptor 3
- Prostaglandin E Receptor 4
- Prostaglandin E Synthase 3
- Prostaglandin F Receptor
- Prostaglandin I2 Receptor
|
|
9 |
|
Eicosanoid ligand-binding receptors
|
26 |
1.069 |
Genes names |
- Prostaglandin D2 Receptor
- Prostaglandin D2 Receptor 2
- Prostaglandin E Receptor 1
- Prostaglandin E Receptor 2
- Prostaglandin E Receptor 3
- Prostaglandin E Receptor 4
- Prostaglandin F Receptor
- Prostaglandin I2 Receptor
|
|
10 |
|
GPCR downstream signalling
|
710 |
1.069 |
Genes names |
- Prostaglandin D2 Receptor
- Prostaglandin D2 Receptor 2
- Prostaglandin E Receptor 1
- Prostaglandin E Receptor 2
- Prostaglandin E Receptor 3
- Prostaglandin E Receptor 4
- Prostaglandin F Receptor
- Prostaglandin I2 Receptor
|
|
11 |
|
Class A/1 (Rhodopsin-like receptors)
|
556 |
1.069 |
Genes names |
- Prostaglandin D2 Receptor
- Prostaglandin D2 Receptor 2
- Prostaglandin E Receptor 1
- Prostaglandin E Receptor 2
- Prostaglandin E Receptor 3
- Prostaglandin E Receptor 4
- Prostaglandin F Receptor
- Prostaglandin I2 Receptor
|
|
12 |
|
Beta-2 adrenergic-dependent CFTR expression
|
167 |
1.000 |
Genes names |
- Prostaglandin E Receptor 2
- Prostaglandin E Receptor 3
- Prostaglandin E Receptor 4
- Prostaglandin E Synthase
- Prostaglandin E Synthase 2
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
|
13 |
|
Platelet Aggregation Inhibitor Pathway, Pharmacodynamics
|
51 |
0.756 |
Genes names |
- Prostaglandin D2 Receptor
- Prostaglandin E Receptor 2
- Prostaglandin I2 Receptor
- Prostaglandin-Endoperoxide Synthase 1
|
|
14 |
|
Metapathway biotransformation Phase I and II
|
296 |
0.756 |
Genes names |
- Hematopoietic Prostaglandin D Synthase
- Prostaglandin E Synthase 3
- Prostaglandin I2 Synthase
- Prostaglandin-Endoperoxide Synthase 1
|
|
15 |
|
G alpha (s) signalling events
|
158 |
0.756 |
Genes names |
- Prostaglandin D2 Receptor
- Prostaglandin E Receptor 2
- Prostaglandin E Receptor 4
- Prostaglandin I2 Receptor
|
|
16 |
|
Relationship between inflammation, COX-2 and EGFR
|
10 |
0.655 |
Genes names |
- Prostaglandin E Receptor 4
- Prostaglandin E Synthase 2
- Prostaglandin-Endoperoxide Synthase 2
|
|
17 |
|
MIF Mediated Glucocorticoid Regulation
|
681 |
0.655 |
Genes names |
- Prostaglandin E Synthase
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
|
18 |
|
Nuclear receptors meta-pathway
|
315 |
0.655 |
Genes names |
- Prostaglandin E Synthase 3
- Prostaglandin Reductase 1
- Prostaglandin-Endoperoxide Synthase 2
|
|
19 |
|
Oxidation by cytochrome P450
|
115 |
0.655 |
Genes names |
- Prostaglandin E Synthase 3
- Prostaglandin I2 Synthase
- Prostaglandin-Endoperoxide Synthase 1
|
|
20 |
|
HETE and HPETE biosynthesis and metabolism
|
21 |
0.655 |
Genes names |
- Prostaglandin I2 Synthase
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
|
21 |
|
Colorectal Cancer Metastasis
|
165 |
0.655 |
Genes names |
- Prostaglandin E Receptor 2
- Prostaglandin E Receptor 4
- Prostaglandin-Endoperoxide Synthase 2
|
|
22 |
|
Development VEGF signaling via VEGFR2 - generic cascades
|
147 |
0.534 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
|
23 |
|
Aspirin and miRNAs
|
10 |
0.534 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
|
24 |
|
NF-kappaB Signaling
|
327 |
0.534 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
|
25 |
|
Thromboxane A2 receptor signaling
|
34 |
0.534 |
Genes names |
- Prostaglandin D2 Receptor
- Prostaglandin I2 Receptor
|
|
26 |
|
p70S6K Signaling
|
392 |
0.534 |
Genes names |
- Prostaglandin I2 Receptor
- Prostaglandin-Endoperoxide Synthase 2
|
|
27 |
|
Etoposide Pathway, Pharmacokinetics/Pharmacodynamics
|
15 |
0.534 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
|
28 |
|
Biosynthesis of specialized proresolving mediators (SPMs)
|
19 |
0.534 |
Genes names |
- Prostaglandin Reductase 1
- Prostaglandin-Endoperoxide Synthase 2
|
|
29 |
|
Nicotinate metabolism
|
31 |
0.534 |
Genes names |
- Prostaglandin I2 Synthase
- Prostaglandin-Endoperoxide Synthase 2
|
|
30 |
|
Neuroscience
|
341 |
0.534 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
|
31 |
|
Metabolism of water-soluble vitamins and cofactors
|
191 |
0.534 |
Genes names |
- Prostaglandin I2 Synthase
- Prostaglandin-Endoperoxide Synthase 2
|
|
32 |
|
Dipyrone Pathway, Pharmacokinetics/Pharmacodynamics
|
4 |
0.534 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
|
33 |
|
Development Ligand-independent activation of ESR1 and ESR2
|
135 |
0.534 |
Genes names |
- Prostaglandin I2 Synthase
- Prostaglandin-Endoperoxide Synthase 2
|
|
34 |
|
Glucocorticoid receptor pathway
|
71 |
0.534 |
Genes names |
- Prostaglandin E Synthase 3
- Prostaglandin-Endoperoxide Synthase 2
|
|
35 |
|
Overview of nanoparticle effects
|
19 |
0.534 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 1
- Prostaglandin-Endoperoxide Synthase 2
|
|
36 |
|
Innate Immune System
|
2025 |
0.534 |
Genes names |
- Prostaglandin E Synthase 2
- Prostaglandin-Endoperoxide Synthase 2
|
|
37 |
|
Potential therapeutics for SARS
|
99 |
0.378 |
Genes names |
- Prostaglandin E Synthase 3
|
|
38 |
|
Small cell lung cancer
|
96 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
39 |
|
TCR Signaling (Qiagen)
|
238 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
40 |
|
Photodynamic therapy-induced NF-kB survival signaling
|
48 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
41 |
|
Gastrin signaling pathway
|
112 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
42 |
|
HSF1-dependent transactivation
|
24 |
0.378 |
Genes names |
- Prostaglandin E Synthase 3
|
|
43 |
|
Alzheimer's disease and miRNA effects
|
267 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
44 |
|
Signaling mediated by p38-alpha and p38-beta
|
33 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
45 |
|
Quercetin and Nf-kB / AP-1 induced apoptosis
|
15 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
46 |
|
Endothelin pathways
|
32 |
0.378 |
Genes names |
- Prostaglandin I2 Receptor
|
|
47 |
|
WNT Signaling
|
250 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
48 |
|
Integrin-mediated cell adhesion
|
140 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
49 |
|
Ovarian infertility
|
36 |
0.378 |
Genes names |
- Prostaglandin E Receptor 2
|
|
50 |
|
Phenytoin Pathway, Pharmacokinetics
|
31 |
0.378 |
Genes names |
- Prostaglandin I2 Synthase
|
|
51 |
|
S1P1 pathway
|
14 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
52 |
|
Mammalian disorder of sexual development
|
25 |
0.378 |
Genes names |
- Prostaglandin D2 Synthase
|
|
53 |
|
Hepatocyte growth factor receptor signaling
|
115 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
54 |
|
Endometrial cancer
|
201 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
55 |
|
Cellular response to heat stress
|
89 |
0.378 |
Genes names |
- Prostaglandin E Synthase 3
|
|
56 |
|
Cellular responses to stimuli
|
802 |
0.378 |
Genes names |
- Prostaglandin E Synthase 3
|
|
57 |
|
ERK Signaling
|
1185 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
58 |
|
Vitamin D receptor pathway
|
185 |
0.378 |
Genes names |
- Prostaglandin E Receptor 4
|
|
59 |
|
Adipogenesis
|
131 |
0.378 |
Genes names |
- Prostaglandin I2 Synthase
|
|
60 |
|
IL-1 Family Signaling Pathways
|
158 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
61 |
|
Metabolism of steroids
|
194 |
0.378 |
Genes names |
- Prostaglandin I2 Synthase
|
|
62 |
|
Biosynthesis of DPA-derived SPMs
|
4 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
63 |
|
BAFF in B-Cell Signaling
|
84 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
64 |
|
Acyl chain remodelling of PE
|
46 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
65 |
|
Development_Glucocorticoid receptor signaling
|
41 |
0.378 |
Genes names |
- Prostaglandin E Synthase 3
|
|
66 |
|
Platelet homeostasis
|
88 |
0.378 |
Genes names |
- Prostaglandin I2 Receptor
|
|
67 |
|
Angiogenesis (CST)
|
89 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
68 |
|
GPCR Pathway
|
712 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
69 |
|
Hematopoietic Stem Cells and Lineage-specific Markers
|
116 |
0.378 |
Genes names |
- Prostaglandin D2 Receptor 2
|
|
70 |
|
CKAP4 signaling pathway map
|
108 |
0.378 |
Genes names |
- Prostaglandin E Receptor 3
|
|
71 |
|
Response to elevated platelet cytosolic Ca2+
|
621 |
0.378 |
Genes names |
- Prostaglandin I2 Receptor
|
|
72 |
|
IL-17 Family Signaling Pathways
|
108 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
73 |
|
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
|
51 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
74 |
|
Cytokine Signaling in Immune system
|
732 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
75 |
|
Genotoxicity pathway
|
60 |
0.378 |
Genes names |
- Prostaglandin E Receptor 4
|
|
76 |
|
Apoptotic Pathways in Synovial Fibroblasts
|
731 |
0.378 |
Genes names |
- Prostaglandin I2 Receptor
|
|
77 |
|
Neuropathic Pain-Signaling in Dorsal Horn Neurons
|
232 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
78 |
|
Aryl hydrocarbon receptor pathway
|
30 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
79 |
|
Interleukin-4 and Interleukin-13 signaling
|
108 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
80 |
|
Photodynamic therapy-induced HIF-1 survival signaling
|
37 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
81 |
|
Synthesis of bile acids and bile salts
|
48 |
0.378 |
Genes names |
- Prostaglandin I2 Synthase
|
|
82 |
|
Nervous system development
|
1168 |
0.378 |
Genes names |
- Prostaglandin D2 Synthase
|
|
83 |
|
GPCRs, other
|
100 |
0.378 |
|
84 |
|
E2F transcription factor network
|
66 |
0.378 |
Genes names |
- Prostaglandin D2 Receptor
|
|
85 |
|
Regulation of Telomerase
|
68 |
0.378 |
Genes names |
- Prostaglandin E Synthase 3
|
|
86 |
|
Innate Lymphoid Cells Differentiation
|
80 |
0.378 |
Genes names |
- Prostaglandin D2 Receptor 2
|
|
87 |
|
Spinal cord injury
|
115 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
88 |
|
IFN-gamma pathway
|
31 |
0.378 |
Genes names |
- Prostaglandin E Synthase 2
|
|
89 |
|
COPI-independent Golgi-to-ER retrograde traffic
|
176 |
0.378 |
Genes names |
- Prostaglandin E Synthase 3
|
|
90 |
|
Interleukin-10 signaling
|
47 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
91 |
|
Toll Comparative Pathway
|
101 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
92 |
|
SARS-CoV-2 Infection
|
414 |
0.378 |
Genes names |
- Prostaglandin E Synthase 3
|
|
93 |
|
Development EGFR signaling via small GTPases
|
70 |
0.378 |
Genes names |
- Prostaglandin I2 Receptor
|
|
94 |
|
Notch-mediated HES/HEY network
|
45 |
0.378 |
Genes names |
- Prostaglandin D2 Synthase
|
|
95 |
|
Infectious disease
|
1747 |
0.378 |
Genes names |
- Prostaglandin E Synthase 3
|
|
96 |
|
ESR-mediated signaling
|
298 |
0.378 |
Genes names |
- Prostaglandin E Synthase 3
|
|
97 |
|
C-MYB transcription factor network
|
80 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
98 |
|
G-Beta Gamma Signaling
|
219 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
99 |
|
Hepatitis C and hepatocellular carcinoma
|
55 |
0.378 |
Genes names |
- Prostaglandin-Endoperoxide Synthase 2
|
|
100 |
|
Glutathione conjugation
|
47 |
0.378 |
Genes names |
- Hematopoietic Prostaglandin D Synthase
|
|