66 search results for cancer
# SuperPathway Name Genes Count Relevance Score
1 TGFBR1 KD Mutants in Cancer 10 1.433
SuperPathway
  • TGFBR1 KD Mutants in Cancer
Pathways
  • SMAD2/3 Phosphorylation Motif Mutants in Cancer
  • Loss of Function of TGFBR2 in Cancer
  • TGFBR2 Kinase Domain Mutants in Cancer
  • TGFBR2 MSI Frameshift Mutants in Cancer
  • TGFBR1 KD Mutants in Cancer
2 Signaling by EGFR in Cancer 28 1.331
SuperPathway
  • Signaling by EGFR in Cancer
Pathways
  • Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
  • Signaling by Ligand-Responsive EGFR Variants in Cancer
  • Signaling by EGFR in Cancer
  • Signaling by EGFRvIII in Cancer
3 Endometrial cancer 201 1.216
SuperPathway
  • Endometrial cancer
Pathways
  • Chromosomal and microsatellite instability in colorectal cancer
  • Endometrial cancer
  • Non-small cell lung cancer
4 SMAD2/3 MH2 Domain Mutants in Cancer 3 1.216
SuperPathway
  • SMAD2/3 MH2 Domain Mutants in Cancer
Pathways
  • SMAD4 MH2 Domain Mutants in Cancer
  • SMAD2/3 MH2 Domain Mutants in Cancer
  • Loss of Function of SMAD4 in Cancer
5 Loss of function of TP53 in cancer due to loss of tetramerization ability 1 1.079
SuperPathway
  • Loss of function of TP53 in cancer due to loss of tetramerization ability
Pathways
  • Loss of function of TP53 in cancer due to loss of tetramerization ability
  • Loss of Function of TP53 in Cancer
6 Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling 5 1.079
SuperPathway
  • Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling
Pathways
  • Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling
  • FBXW7 Mutants and NOTCH1 in Cancer
7 Androgen receptor network in prostate cancer 105 1.079
SuperPathway
  • Androgen receptor network in prostate cancer
Pathways
  • Androgen receptor network in prostate cancer
  • Integrated cancer pathway
8 Signaling by ALK in cancer 55 1.079
SuperPathway
  • Signaling by ALK in cancer
Pathways
  • Nuclear events stimulated by ALK signaling in cancer
  • Signaling by ALK in cancer
9 Small cell lung cancer 96 0.900
SuperPathway
  • Small cell lung cancer
Pathways
  • Small cell lung cancer
10 NRP1-triggered signaling pathways in pancreatic cancer 53 0.900
SuperPathway
  • NRP1-triggered signaling pathways in pancreatic cancer
Pathways
  • NRP1-triggered signaling pathways in pancreatic cancer
11 Signaling by Overexpressed Wild-Type EGFR in Cancer 24 0.900
SuperPathway
  • Signaling by Overexpressed Wild-Type EGFR in Cancer
Pathways
  • Signaling by Overexpressed Wild-Type EGFR in Cancer
12 Apoptosis-related network due to altered Notch3 in ovarian cancer 52 0.900
SuperPathway
  • Apoptosis-related network due to altered Notch3 in ovarian cancer
Pathways
  • Apoptosis-related network due to altered Notch3 in ovarian cancer
13 Metabolic reprogramming in colon cancer 42 0.900
SuperPathway
  • Metabolic reprogramming in colon cancer
Pathways
  • Metabolic reprogramming in colon cancer
14 Breast cancer pathway 199 0.900
SuperPathway
  • Breast cancer pathway
Pathways
  • Breast cancer pathway
15 Cancer immunotherapy by CTLA4 blockade 15 0.900
SuperPathway
  • Cancer immunotherapy by CTLA4 blockade
Pathways
  • Cancer immunotherapy by CTLA4 blockade
16 Cancer immunotherapy by PD-1 blockade 23 0.900
SuperPathway
  • Cancer immunotherapy by PD-1 blockade
Pathways
  • Cancer immunotherapy by PD-1 blockade
17 Constitutive Signaling by AKT1 E17K in Cancer 38 0.900
SuperPathway
  • Constitutive Signaling by AKT1 E17K in Cancer
Pathways
  • Constitutive Signaling by AKT1 E17K in Cancer
18 Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors 3 0.900
SuperPathway
  • Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors
Pathways
  • Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors
19 miRNA regulation of p53 pathway in prostate cancer 32 0.900
SuperPathway
  • miRNA regulation of p53 pathway in prostate cancer
Pathways
  • miRNA regulation of p53 pathway in prostate cancer
20 Folate-alcohol and cancer pathway hypotheses 9 0.900
SuperPathway
  • Folate-alcohol and cancer pathway hypotheses
Pathways
  • Folate-alcohol and cancer pathway hypotheses
21 Gastric cancer network 2 31 0.900
SuperPathway
  • Gastric cancer network 2
Pathways
  • Gastric cancer network 2
22 Interactions of natural killer cells in pancreatic cancer 27 0.900
SuperPathway
  • Interactions of natural killer cells in pancreatic cancer
Pathways
  • Interactions of natural killer cells in pancreatic cancer
23 Glucose metabolism in triple-negative breast cancer cells 8 0.900
SuperPathway
  • Glucose metabolism in triple-negative breast cancer cells
Pathways
  • Glucose metabolism in triple-negative breast cancer cells
24 Methotrexate Pathway (Cancer Cell), Pharmacodynamics and Pharmacokinetics 34 0.900
SuperPathway
  • Methotrexate Pathway (Cancer Cell), Pharmacodynamics and Pharmacokinetics
Pathways
  • Methotrexate Pathway (Cancer Cell), Pharmacodynamics and Pharmacokinetics
25 MicroRNA for targeting cancer growth and vascularization in glioblastoma 7 0.900
SuperPathway
  • MicroRNA for targeting cancer growth and vascularization in glioblastoma
Pathways
  • MicroRNA for targeting cancer growth and vascularization in glioblastoma
26 Epithelial to mesenchymal transition in colorectal cancer 161 0.900
SuperPathway
  • Epithelial to mesenchymal transition in colorectal cancer
Pathways
  • Epithelial to mesenchymal transition in colorectal cancer
27 Immune infiltration in pancreatic cancer 39 0.900
SuperPathway
  • Immune infiltration in pancreatic cancer
Pathways
  • Immune infiltration in pancreatic cancer
28 Neural crest cell migration in cancer 34 0.900
SuperPathway
  • Neural crest cell migration in cancer
Pathways
  • Neural crest cell migration in cancer
29 Signaling by FGFR3 fusions in cancer 1 0.900
SuperPathway
  • Signaling by FGFR3 fusions in cancer
Pathways
  • Signaling by FGFR3 fusions in cancer
30 Integrated breast cancer pathway 150 0.900
SuperPathway
  • Integrated breast cancer pathway
Pathways
  • Integrated breast cancer pathway
31 Bladder cancer 40 0.900
SuperPathway
  • Bladder cancer
Pathways
  • Bladder cancer
32 MAPK pathway in congenital thyroid cancer 11 0.900
SuperPathway
  • MAPK pathway in congenital thyroid cancer
Pathways
  • MAPK pathway in congenital thyroid cancer
33 Cell interactions of the pancreatic cancer microenvironment 28 0.900
SuperPathway
  • Cell interactions of the pancreatic cancer microenvironment
Pathways
  • Cell interactions of the pancreatic cancer microenvironment
34 Retinoblastoma gene in cancer 86 0.900
SuperPathway
  • Retinoblastoma gene in cancer
Pathways
  • Retinoblastoma gene in cancer
35 T cell modulation in pancreatic cancer 45 0.900
SuperPathway
  • T cell modulation in pancreatic cancer
Pathways
  • T cell modulation in pancreatic cancer
36 Senescence and autophagy in cancer 105 0.900
SuperPathway
  • Senescence and autophagy in cancer
Pathways
  • Senescence and autophagy in cancer
37 Gastric cancer network 1 29 0.900
SuperPathway
  • Gastric cancer network 1
Pathways
  • Gastric cancer network 1
38 Metabolic reprogramming in pancreatic cancer 42 0.900
SuperPathway
  • Metabolic reprogramming in pancreatic cancer
Pathways
  • Metabolic reprogramming in pancreatic cancer
39 Deregulation of Rab and Rab effector genes in bladder cancer 16 0.900
SuperPathway
  • Deregulation of Rab and Rab effector genes in bladder cancer
Pathways
  • Deregulation of Rab and Rab effector genes in bladder cancer
40 Colorectal Cancer Metastasis 165 0.900
SuperPathway
  • Colorectal Cancer Metastasis
Pathways
  • Colorectal Cancer Metastasis
41 TGF-beta receptor signaling activates SMADs 46 0.863
Pathways
  • Loss of Function of SMAD2/3 in Cancer
  • Loss of Function of TGFBR1 in Cancer
  • TGFBR1 LBD Mutants in Cancer
  • Signaling by TGF-beta Receptor Complex in Cancer
42 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 74 0.748
Pathways
  • Signaling by NOTCH1 PEST Domain Mutants in Cancer
  • Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
  • Signaling by NOTCH1 in Cancer
43 EML4 and NUDC in mitotic spindle formation 248 0.620
Genes names
  • Suppressor Of Cancer Cell Invasion
44 ncRNAs involved in STAT3 signaling in hepatocellular carcinoma 18 0.620
Genes names
  • Urothelial Cancer Associated 1
45 Signaling by Rho GTPases 722 0.620
Genes names
  • Suppressor Of Cancer Cell Invasion
46 RhoA signaling pathway 36 0.620
Genes names
  • Suppressor Of Cancer Cell Invasion
47 pyrimidine deoxyribonucleotides biosynthesis from CTP 16 0.620
Genes names
  • Nucleoside-Triphosphatase, Cancer-Related
48 Cytoskeletal Signaling 308 0.620
Genes names
  • Suppressor Of Cancer Cell Invasion
49 Pyrimidine metabolism 85 0.620
Genes names
  • Nucleoside-Triphosphatase, Cancer-Related
50 Signal Transduction 2590 0.620
Genes names
  • Suppressor Of Cancer Cell Invasion
51 Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) 88 0.611
Pathways
  • Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects
  • Aberrant regulation of mitotic exit in cancer due to RB1 defects
52 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 135 0.611
Pathways
  • Constitutive Signaling by Aberrant PI3K in Cancer
  • PI3K/AKT Signaling in Cancer
53 TP53 Regulates Transcription of Cell Cycle Genes 48 0.432
Pathways
  • Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer
54 NOTCH2 Activation and Transmission of Signal to the Nucleus 50 0.432
Pathways
  • Signaling by NOTCH1 HD Domain Mutants in Cancer
55 Transport of inorganic cations/anions and amino acids/oligopeptides 728 0.432
Pathways
  • Defective SLC22A18 causes lung cancer (LNCR) and embryonal rhabdomyosarcoma 1 (RMSE1)
56 CTNNB1 S33 mutants aren't phosphorylated 58 0.432
Pathways
  • Signaling by WNT in cancer
57 Transcriptional Regulation by MECP2 62 0.432
Pathways
  • PTEN Loss of Function in Cancer
58 ERK Signaling 1185 0.432
Pathways
  • Molecular Mechanisms of Cancer
59 Doxorubicin Pathway, Pharmacokinetics 28 0.432
Pathways
  • Doxorubicin Pathway (Cancer Cell), Pharmacodynamics
60 serine and glycine biosynthesis 18 0.432
Pathways
  • Amino acid metabolism in triple-negative breast cancer cells
61 Prolactin Signaling 432 0.432
Pathways
  • TCA cycle nutrient use and invasiveness of ovarian cancer
62 GPCR Pathway 712 0.432
Pathways
  • Breast Cancer Regulation by Stathmin1
63 MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 21 0.432
Pathways
  • MFAP5-mediated ovarian cancer cell motility and invasiveness
64 PPAR signaling pathway 69 0.432
Pathways
  • FABP4 in ovarian cancer
65 ncRNAs involved in Wnt signaling in hepatocellular carcinoma 220 0.432
Pathways
  • lncRNA in canonical Wnt signaling and colorectal cancer
66 Signaling by ERBB2 KD Mutants 29 0.432
Pathways
  • Signaling by ERBB2 in Cancer