90 search results for gene
# SuperPathway Name Genes Count Relevance Score
1 Gene Silencing by RNA 191 1.721
SuperPathway
  • Gene Silencing by RNA
Genes names
  • Piwi Like RNA-Mediated Gene Silencing 1
  • Piwi Like RNA-Mediated Gene Silencing 2
  • Piwi Like RNA-Mediated Gene Silencing 4
Pathways
  • Gene Silencing by RNA
2 Gene expression (Transcription) 1502 1.721
SuperPathway
  • Gene expression (Transcription)
Genes names
  • Piwi Like RNA-Mediated Gene Silencing 1
  • Piwi Like RNA-Mediated Gene Silencing 2
  • Piwi Like RNA-Mediated Gene Silencing 4
Pathways
  • Gene expression (Transcription)
3 RNA Polymerase I Promoter Opening 479 1.530
Genes names
  • N-Acetyltransferase 8B (Putative, Gene/Pseudogene)
Pathways
  • Epigenetic regulation of gene expression
  • Binding of TCF/LEF:CTNNB1 to target gene promoters
  • Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
  • Activation of HOX genes during differentiation
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
4 Formation of HIV elongation complex in the absence of HIV Tat 180 1.411
Genes names
  • Piwi Like RNA-Mediated Gene Silencing 1
  • Piwi Like RNA-Mediated Gene Silencing 2
  • Piwi Like RNA-Mediated Gene Silencing 4
Pathways
  • TP53 Regulates Transcription of DNA Repair Genes
  • RNA polymerase II transcribes snRNA genes
5 TP53 Regulates Transcription of Cell Cycle Genes 48 1.368
SuperPathway
  • TP53 Regulates Transcription of Cell Cycle Genes
Pathways
  • TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
  • TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
  • TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
  • TP53 Regulates Transcription of Cell Cycle Genes
6 TP53 Regulates Transcription of Cell Death Genes 44 1.251
SuperPathway
  • TP53 Regulates Transcription of Cell Death Genes
Pathways
  • TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
  • TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
  • TP53 Regulates Transcription of Cell Death Genes
7 PERK regulates gene expression 32 1.111
SuperPathway
  • PERK regulates gene expression
Pathways
  • PERK regulates gene expression
  • ATF4 activates genes in response to endoplasmic reticulum stress
8 RUNX1 regulates transcription of genes involved in differentiation of myeloid cells 7 1.111
SuperPathway
  • RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
Pathways
  • RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
  • RUNX2 regulates genes involved in differentiation of myeloid cells
9 RUNX1 regulates transcription of genes involved in BCR signaling 8 1.111
SuperPathway
  • RUNX1 regulates transcription of genes involved in BCR signaling
Pathways
  • RUNX1 regulates transcription of genes involved in BCR signaling
  • RUNX1 regulates transcription of genes involved in interleukin signaling
10 Metabolism of steroids 194 1.084
Genes names
  • Insulin Induced Gene 1
  • Insulin Induced Gene 2
Pathways
  • Activation of gene expression by SREBF (SREBP)
11 NR1H2 and NR1H3-mediated signaling 47 1.073
Pathways
  • NR1H2 and NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose
  • NR1H2 and NR1H3 regulate gene expression to control bile acid homeostasis
  • NR1H3 and NR1H2 regulate gene expression linked to cholesterol transport and efflux
  • NR1H2 and NR1H3 regulate gene expression linked to lipogenesis
  • NR1H2 and NR1H3 regulate gene expression to limit cholesterol uptake
  • NR1H2 and NR1H3 regulate gene expression linked to gluconeogenesis
12 Metabolism 2117 1.021
Genes names
  • Aldo-Keto Reductase Family 7 Like (Gene/Pseudogene)
  • Glucosylceramidase Beta 3 (Gene/Pseudogene)
  • Glutathione S-Transferase Theta 2 (Gene/Pseudogene)
  • Insulin Induced Gene 1
  • Insulin Induced Gene 2
13 Olfactory Signaling Pathway 619 1.021
Genes names
  • Olfactory Receptor Family 10 Subfamily A Member 6 (Gene/Pseudogene)
  • Olfactory Receptor Family 11 Subfamily H Member 7 (Gene/Pseudogene)
  • Olfactory Receptor Family 52 Subfamily E Member 1 (Gene/Pseudogene)
  • Olfactory Receptor Family 5 Subfamily AL Member 1 (Gene/Pseudogene)
  • Olfactory Receptor Family 8 Subfamily K Member 3 (Gene/Pseudogene)
14 IL-2 Gene Expression in Activated and Quiescent T-Cells 35 0.930
SuperPathway
  • IL-2 Gene Expression in Activated and Quiescent T-Cells
Pathways
  • IL-2 Gene Expression in Activated and Quiescent T-Cells
15 Transcription_Role of VDR in regulation of genes involved in osteoporosis 45 0.930
SuperPathway
  • Transcription_Role of VDR in regulation of genes involved in osteoporosis
Pathways
  • Transcription_Role of VDR in regulation of genes involved in osteoporosis
16 p53 transcriptional gene network 72 0.930
SuperPathway
  • p53 transcriptional gene network
Pathways
  • p53 transcriptional gene network
17 Hematopoietic stem cell gene regulation by GABP alpha/beta complex 20 0.930
SuperPathway
  • Hematopoietic stem cell gene regulation by GABP alpha/beta complex
Pathways
  • Hematopoietic stem cell gene regulation by GABP alpha/beta complex
18 Genes targeted by miRNAs in adipocytes 13 0.930
SuperPathway
  • Genes targeted by miRNAs in adipocytes
Pathways
  • Genes targeted by miRNAs in adipocytes
19 Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome 37 0.930
SuperPathway
  • Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome
Pathways
  • Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome
20 Antiviral mechanism by IFN-stimulated genes 80 0.930
SuperPathway
  • Antiviral mechanism by IFN-stimulated genes
Pathways
  • Antiviral mechanism by IFN-stimulated genes
21 Transcriptional activation of p53 responsive genes 4 0.930
SuperPathway
  • Transcriptional activation of p53 responsive genes
Pathways
  • Transcriptional activation of p53 responsive genes
22 Genes related to primary cilium development (based on CRISPR) 52 0.930
SuperPathway
  • Genes related to primary cilium development (based on CRISPR)
Pathways
  • Genes related to primary cilium development (based on CRISPR)
23 Genes controlling nephrogenesis 44 0.930
SuperPathway
  • Genes controlling nephrogenesis
Pathways
  • Genes controlling nephrogenesis
24 Genes associated with the development of rheumatoid arthritis 18 0.930
SuperPathway
  • Genes associated with the development of rheumatoid arthritis
Pathways
  • Genes associated with the development of rheumatoid arthritis
25 Regulation of nuclear beta catenin signaling and target gene transcription 72 0.930
SuperPathway
  • Regulation of nuclear beta catenin signaling and target gene transcription
Pathways
  • Regulation of nuclear beta catenin signaling and target gene transcription
26 PPARA activates gene expression 145 0.930
SuperPathway
  • PPARA activates gene expression
Pathways
  • PPARA activates gene expression
27 Rett syndrome causing genes 48 0.930
SuperPathway
  • Rett syndrome causing genes
Pathways
  • Rett syndrome causing genes
28 YAP1- and WWTR1 (TAZ)-stimulated gene expression 15 0.930
SuperPathway
  • YAP1- and WWTR1 (TAZ)-stimulated gene expression
Pathways
  • YAP1- and WWTR1 (TAZ)-stimulated gene expression
29 RUNX1 regulates transcription of genes involved in differentiation of keratinocytes 8 0.930
SuperPathway
  • RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
Pathways
  • RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
30 RUNX1 regulates transcription of genes involved in WNT signaling 6 0.930
SuperPathway
  • RUNX1 regulates transcription of genes involved in WNT signaling
Pathways
  • RUNX1 regulates transcription of genes involved in WNT signaling
31 Lissencephaly gene (LIS1) in neuronal migration and development 28 0.930
SuperPathway
  • Lissencephaly gene (LIS1) in neuronal migration and development
Pathways
  • Lissencephaly gene (LIS1) in neuronal migration and development
32 Deregulation of Rab and Rab effector genes in bladder cancer 16 0.930
SuperPathway
  • Deregulation of Rab and Rab effector genes in bladder cancer
Pathways
  • Deregulation of Rab and Rab effector genes in bladder cancer
33 TP53 Regulates Metabolic Genes 87 0.930
SuperPathway
  • TP53 Regulates Metabolic Genes
Pathways
  • TP53 Regulates Metabolic Genes
34 Gene regulatory network modelling somitogenesis 12 0.930
SuperPathway
  • Gene regulatory network modelling somitogenesis
Pathways
  • Gene regulatory network modelling somitogenesis
35 Circadian rhythm genes 2 0.930
SuperPathway
  • Circadian rhythm genes
Pathways
  • Circadian rhythm genes
36 Retinoblastoma gene in cancer 86 0.930
SuperPathway
  • Retinoblastoma gene in cancer
Pathways
  • Retinoblastoma gene in cancer
37 Male infertility 52 0.914
Genes names
  • Piwi Like RNA-Mediated Gene Silencing 1
  • Piwi Like RNA-Mediated Gene Silencing 2
  • Piwi Like RNA-Mediated Gene Silencing 3
  • Piwi Like RNA-Mediated Gene Silencing 4
38 Regulation of beta-cell development 41 0.876
Pathways
  • Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells
  • Regulation of gene expression in beta cells
  • Regulation of gene expression in early pancreatic precursor cells
  • Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
39 22q11.2 copy number variation syndrome 133 0.791
Genes names
  • DiGeorge Syndrome Critical Region Gene 2
  • DiGeorge Syndrome Critical Region Gene 5
  • DiGeorge Syndrome Critical Region Gene 6 Like
40 Circadian Clock 85 0.759
Pathways
  • BMAL1:CLOCK,NPAS2 activates circadian gene expression
  • RORA activates gene expression
  • NR1D1 (REV-ERBA) represses gene expression
41 FOXO-mediated transcription 65 0.759
Pathways
  • FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
  • FOXO-mediated transcription of cell death genes
  • FOXO-mediated transcription of cell cycle genes
42 Unfolded Protein Response (UPR) 94 0.759
Pathways
  • XBP1(S) activates chaperone genes
  • ATF6 (ATF6-alpha) activates chaperone genes
  • CREB3 factors activate genes
43 Regulation of activated PAK-2p34 by proteasome mediated degradation 943 0.759
Pathways
  • RUNX2 regulates genes involved in cell migration
  • Repression of WNT target genes
  • Regulation of gene expression by Hypoxia-inducible Factor
44 Overview of interferons-mediated signaling pathway 163 0.646
Genes names
  • Interferon Lambda 4 (Gene/Pseudogene)
  • Interferon Stimulated Exonuclease Gene 20
45 Vitamin D receptor pathway 185 0.646
Genes names
  • Cellular Repressor Of E1A Stimulated Genes 2
  • Maternally Expressed 8, Small Nucleolar RNA Host Gene
46 miRNAs involvement in the immune response in sepsis 62 0.646
Genes names
  • MIR155 Host Gene
  • MIR223 Host Gene
47 Innate Immune System 2016 0.646
Genes names
  • Cellular Repressor Of E1A Stimulated Genes 1
  • Interferon Stimulated Exonuclease Gene 20
48 Metapathway biotransformation Phase I and II 296 0.646
Genes names
  • Aldo-Keto Reductase Family 7 Like (Gene/Pseudogene)
  • Glutathione S-Transferase Theta 2 (Gene/Pseudogene)
49 Metal ion SLC transporters 47 0.620
Pathways
  • MTF1 activates gene expression
  • Zinc influx into cells by the SLC39 gene family
50 Processing of Capped Intron-Containing Pre-mRNA 706 0.457
Genes names
  • Interferon Stimulated Exonuclease Gene 20 Like 2
51 ncRNAs involved in Wnt signaling in hepatocellular carcinoma 219 0.457
Genes names
  • MIR34A Host Gene
52 Glutathione conjugation 47 0.457
Genes names
  • Glutathione S-Transferase Theta 2 (Gene/Pseudogene)
53 Translational Control 190 0.457
Genes names
  • Piwi Like RNA-Mediated Gene Silencing 1
54 OSX and miRNAs in tooth development 33 0.457
Genes names
  • MIR34A Host Gene
55 PKMTs methylate histone lysines 86 0.457
Genes names
  • SET Domain And Mariner Transposase Fusion Gene
56 GPCRs, other 101 0.457
Genes names
  • Olfactory Receptor Family 1 Subfamily E Member 3 (Gene/Pseudogene)
57 Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics 20 0.457
Genes names
  • Insulin Induced Gene 2
58 Oxysterols derived from cholesterol 33 0.457
Genes names
  • Insulin Induced Gene 1
59 Prion disease pathway 32 0.457
Genes names
  • Caspase 12 (Gene/Pseudogene)
60 Apoptotic Pathways in Synovial Fibroblasts 731 0.457
Genes names
  • Caspase 12 (Gene/Pseudogene)
61 Aflatoxin activation and detoxification 19 0.457
Genes names
  • Aldo-Keto Reductase Family 7 Like (Gene/Pseudogene)
62 Corticotropin-releasing hormone signaling pathway 91 0.457
Genes names
  • Caspase 12 (Gene/Pseudogene)
63 Amyotrophic lateral sclerosis (ALS) 36 0.457
Genes names
  • Caspase 12 (Gene/Pseudogene)
64 Toll-like receptor signaling pathway 285 0.457
Genes names
  • Caspase 12 (Gene/Pseudogene)
65 Metabolism of proteins 1968 0.457
Genes names
  • N-Acetyltransferase 8B (Putative, Gene/Pseudogene)
66 Digestion and absorption 27 0.457
Genes names
  • Pancreatic Lipase Related Protein 2 (Gene/Pseudogene)
67 Oxidative stress response 33 0.457
Genes names
  • Glutathione S-Transferase Theta 2 (Gene/Pseudogene)
68 VEGF Pathway (Tocris) 58 0.457
Genes names
  • Caspase 12 (Gene/Pseudogene)
69 Alzheimer's disease and miRNA effects 267 0.457
Genes names
  • Caspase 12 (Gene/Pseudogene)
70 Chks in Checkpoint Regulation 102 0.457
Genes names
  • Insulin Induced Gene 1
71 rRNA processing in the nucleus and cytosol 204 0.457
Genes names
  • Interferon Stimulated Exonuclease Gene 20 Like 2
72 Glycosphingolipid metabolism 93 0.457
Genes names
  • Glucosylceramidase Beta 3 (Gene/Pseudogene)
73 Nuclear receptors meta-pathway 315 0.457
Genes names
  • Glutathione S-Transferase Theta 2 (Gene/Pseudogene)
74 NF-kappaB Pathway 152 0.457
Genes names
  • Caspase 12 (Gene/Pseudogene)
75 Interferon gamma signaling 199 0.457
Genes names
  • Interferon Stimulated Exonuclease Gene 20
76 MAPK-Erk Pathway 275 0.457
Genes names
  • Polycystin 1 Like 2 (Gene/Pseudogene)
77 Senescence and autophagy in cancer 105 0.457
Genes names
  • Cellular Repressor Of E1A Stimulated Genes 1
78 Cytokine Signaling in Immune system 715 0.457
Genes names
  • Interferon Stimulated Exonuclease Gene 20
79 Transcriptional regulation of pluripotent stem cells 24 0.438
Pathways
  • POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
80 Bisphosphonate Pathway, Pharmacodynamics 22 0.438
Pathways
  • RalA downstream regulated genes
81 Tumor suppressor activity of SMARCB1 31 0.438
Pathways
  • GLI proteins bind promoters of Hh responsive genes to promote transcription
82 Human Early Embryo Development 7 0.438
Pathways
  • POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation
83 Interleukin-12 family signaling 57 0.438
Pathways
  • Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
84 ECM proteoglycans 121 0.438
Pathways
  • MED and pseudoachondroplasia genes
85 PIP3 activates AKT signaling 309 0.438
Pathways
  • Regulation of PTEN gene transcription
86 Transcriptional Regulation by MECP2 62 0.438
Pathways
  • MECP2 regulates transcription of genes involved in GABA signaling
87 Assembly of the pre-replicative complex 318 0.438
Pathways
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
88 ESR-mediated signaling 299 0.438
Pathways
  • Estrogen-dependent gene expression
89 RNA Polymerase II Transcription Initiation And Promoter Clearance 205 0.438
Pathways
  • Transcription Ligand-Dependent Transcription of Retinoid-Target genes
90 Integration of energy metabolism 108 0.438
Pathways
  • ChREBP activates metabolic gene expression