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178 search results for p53
# SuperPathway Name Genes Count Relevance Score
1 Direct p53 effectors 128 2.021
SuperPathway
  • Direct p53 effectors
Genes names
  • Junction Mediating And Regulatory Protein, P53 Cofactor
  • P53 Apoptosis Effector Related To PMP22
  • P53-Induced Death Domain Protein 1
  • Tumor Protein P53
  • Tumor Protein P53 Inducible Protein 3
  • Tumor Protein P53 Inducible Nuclear Protein 1
Pathways
  • Direct p53 effectors
2 p53 transcriptional gene network 95 1.953
SuperPathway
  • p53 transcriptional gene network
Genes names
  • P53 Apoptosis Effector Related To PMP22
  • P53-Induced Death Domain Protein 1
  • Tumor Protein P53 Regulated Apoptosis Inducing Protein 1
  • Tumor Protein P53 Inducible Protein 3
  • Tumor Protein P53 Inducible Nuclear Protein 1
Pathways
  • p53 transcriptional gene network
3 p53 Signaling 117 1.801
SuperPathway
  • p53 Signaling
Genes names
  • Tumor Protein P53
Pathways
  • p53 Pathway
  • p53 Signaling
4 miRNA regulation of p53 pathway in prostate cancer 32 1.791
SuperPathway
  • miRNA regulation of p53 pathway in prostate cancer
Genes names
  • P53 Apoptosis Effector Related To PMP22
  • Tumor Protein P53
  • Tumor Protein P53 Regulated Apoptosis Inducing Protein 1
Pathways
  • miRNA regulation of p53 pathway in prostate cancer
5 p53 pathway 50 1.791
SuperPathway
  • p53 pathway
Genes names
  • MDM4 Regulator Of P53
  • Tumor Protein P53
  • Tumor Protein P53 Regulated Apoptosis Inducing Protein 1
Pathways
  • p53 pathway
6 Regulation of activated PAK-2p34 by proteasome mediated degradation 978 1.775
Genes names
  • MDM4 Regulator Of P53
  • Tumor Protein P53
Pathways
  • Stabilization of p53
  • p53-Dependent G1/S DNA damage checkpoint
  • p53-Independent DNA Damage Response
  • p53-Dependent G1 DNA Damage Response
  • p53-Independent G1/S DNA damage checkpoint
7 Transcriptional activation of p53 responsive genes 4 1.557
SuperPathway
  • Transcriptional activation of p53 responsive genes
Genes names
  • Tumor Protein P53
Pathways
  • Transcriptional activation of p53 responsive genes
8 TP53 Regulates Transcription of Cell Death Genes 44 1.439
Genes names
  • P53 Apoptosis Effector Related To PMP22
  • P53-Induced Death Domain Protein 1
  • Tumor Protein P53
  • Tumor Protein P53 Regulated Apoptosis Inducing Protein 1
  • Tumor Protein P53 Binding Protein 2
  • Tumor Protein P53 Inducible Protein 3
  • Tumor Protein P53 Inducible Nuclear Protein 1
Pathways
  • TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
9 Apoptotic Pathways in Synovial Fibroblasts 731 1.232
Genes names
  • P53 Apoptosis Effector Related To PMP22
  • Tumor Protein P53
  • Tumor Protein P53 Regulated Apoptosis Inducing Protein 1
  • Tumor Protein P53 Binding Protein 2
Pathways
  • p53 Mediated Apoptosis
10 Gene expression (Transcription) 1546 0.962
Genes names
  • Junction Mediating And Regulatory Protein, P53 Cofactor
  • MDM4 Regulator Of P53
  • P53 Apoptosis Effector Related To PMP22
  • P53-Induced Death Domain Protein 1
  • Tumor Protein P53
  • Tumor Protein P53 Regulated Apoptosis Inducing Protein 1
  • Tumor Protein P53 Binding Protein 2
  • Tumor Protein P53 Inducible Protein 3
  • Tumor Protein P53 Inducible Nuclear Protein 1
11 Regulation of TP53 Activity 362 0.962
Genes names
  • Junction Mediating And Regulatory Protein, P53 Cofactor
  • MDM4 Regulator Of P53
  • P53 Apoptosis Effector Related To PMP22
  • P53-Induced Death Domain Protein 1
  • Tumor Protein P53
  • Tumor Protein P53 Regulated Apoptosis Inducing Protein 1
  • Tumor Protein P53 Binding Protein 2
  • Tumor Protein P53 Inducible Protein 3
  • Tumor Protein P53 Inducible Nuclear Protein 1
12 TP53 Regulates Transcription of Cell Cycle Genes 48 0.912
Genes names
  • Tumor Protein P53
Pathways
  • TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
13 Proteolysis Putative SUMO-1 pathway 40 0.912
Genes names
  • Tumor Protein P53
Pathways
  • DNA damage Role of SUMO in p53 regulation
14 ATM Pathway 51 0.641
Genes names
  • MDM4 Regulator Of P53
  • P53-Induced Death Domain Protein 1
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 1
15 DNA Damage 296 0.555
Genes names
  • Cell Death Inducing P53 Target 1
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 1
16 Metabolism of proteins 1970 0.555
Genes names
  • MDM4 Regulator Of P53
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 1
17 miRNA regulation of DNA damage response 74 0.555
Genes names
  • P53-Induced Death Domain Protein 1
  • Tumor Protein P53
  • Tumor Protein P53 Regulated Apoptosis Inducing Protein 1
18 Cell Cycle, Mitotic 691 0.555
Genes names
  • MDM4 Regulator Of P53
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 1
19 Cell Cycle Checkpoints 293 0.555
Genes names
  • MDM4 Regulator Of P53
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 1
20 Programmed Cell Death 213 0.454
Genes names
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 2
21 Transport of the SLBP independent Mature mRNA 285 0.454
Genes names
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 1
22 DNA IR-double strand breaks and cellular response via ATM 65 0.454
Genes names
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 1
23 Death Receptor Signaling Pathway 119 0.454
Genes names
  • P53-Induced Death Domain Protein 1
  • Tumor Protein P53
24 p73 transcription factor network 76 0.454
Genes names
  • Tumor Protein P53 Regulated Apoptosis Inducing Protein 1
  • Tumor Protein P53 Inducible Protein 3
25 DNA damage_Role of Brca1 and Brca2 in DNA repair 40 0.454
Genes names
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 1
26 MIF Mediated Glucocorticoid Regulation 681 0.454
Genes names
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 2
27 Cellular responses to stimuli 802 0.454
Genes names
  • MDM4 Regulator Of P53
  • Tumor Protein P53
28 ERK Signaling 1185 0.454
Genes names
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 2
29 Deubiquitination 298 0.454
Genes names
  • MDM4 Regulator Of P53
  • Tumor Protein P53
30 11p11.2 copy number variation syndrome 144 0.454
Genes names
  • Tumor Protein P53
  • Tumor Protein P53 Inducible Protein 11
31 Oncogene Induced Senescence 33 0.454
Genes names
  • MDM4 Regulator Of P53
  • Tumor Protein P53
32 DNA Double Strand Break Response 91 0.454
Genes names
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 1
33 Prolactin Signaling 432 0.454
Genes names
  • MDM4 Regulator Of P53
  • Tumor Protein P53
34 Validated transcriptional targets of TAp63 isoforms 54 0.454
Genes names
  • P53 Apoptosis Effector Related To PMP22
  • Tumor Protein P53 Inducible Protein 3
35 GPCR Pathway 712 0.454
Genes names
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 2
36 Cellular Senescence 196 0.454
Genes names
  • MDM4 Regulator Of P53
  • Tumor Protein P53
37 Homology Directed Repair 346 0.454
Genes names
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 1
38 DNA IR-damage and cellular response via ATR 81 0.454
Genes names
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 1
39 Apoptosis modulation and signaling 32 0.454
Genes names
  • P53-Induced Death Domain Protein 1
  • Tumor Protein P53
40 Malignant pleural mesothelioma 409 0.454
Genes names
  • MDM4 Regulator Of P53
  • Tumor Protein P53
41 P38 MAPK Signaling Pathway (sino) 61 0.454
Genes names
  • Tumor Protein P53 Regulated Apoptosis Inducing Protein 1
  • Tumor Protein P53 Inducible Protein 3
42 Intrinsic Pathway for Apoptosis 55 0.454
Genes names
  • Tumor Protein P53
  • Tumor Protein P53 Binding Protein 2
43 Regulation of TP53 Expression and Degradation 37 0.454
Genes names
  • MDM4 Regulator Of P53
  • Tumor Protein P53
44 Beta-Adrenergic Signaling 333 0.321
Genes names
  • Tumor Protein P53 Binding Protein 2
45 Pathways affected in adenoid cystic carcinoma 62 0.321
Genes names
  • Tumor Protein P53
46 Apoptosis and Autophagy 185 0.321
Genes names
  • Cell Death Inducing P53 Target 1
47 Small cell lung cancer 96 0.321
Genes names
  • Tumor Protein P53
48 16p11.2 proximal deletion syndrome 72 0.321
Genes names
  • Tumor Protein P53
49 PIP3 activates AKT signaling 310 0.321
Genes names
  • Tumor Protein P53
50 AMP-activated protein kinase signaling 100 0.321
Genes names
  • Tumor Protein P53
51 BRCA1 Pathway 64 0.321
Genes names
  • Tumor Protein P53
52 Autophagy in pancreatic ductal adenocarcinoma 20 0.321
Genes names
  • Tumor Protein P53
53 Signaling mediated by p38-alpha and p38-beta 33 0.321
Genes names
  • Tumor Protein P53
54 Autophagy pathway 228 0.321
Genes names
  • Tumor Protein P53
55 Aurora A signaling 33 0.321
Genes names
  • Tumor Protein P53
56 PLK3 signaling events 6 0.321
Genes names
  • Tumor Protein P53
57 Akt Signaling 682 0.321
Genes names
  • Tumor Protein P53
58 LKB1 signaling events 37 0.321
Genes names
  • Tumor Protein P53
59 Unfolded protein response 22 0.321
Genes names
  • Tumor Protein P53
60 Breast cancer pathway 199 0.321
Genes names
  • Tumor Protein P53
61 Amyotrophic lateral sclerosis (ALS) 36 0.321
Genes names
  • Tumor Protein P53
62 ATM signaling in development and disease 45 0.321
Genes names
  • Tumor Protein P53 Binding Protein 1
63 DNA damage_ATM/ATR regulation of G1/S checkpoint 44 0.321
Genes names
  • Tumor Protein P53
64 NF-kappaB Signaling 327 0.321
Genes names
  • Cell Death Inducing P53 Target 1
65 MAPK Signaling: Mitogens 108 0.321
Genes names
  • Tumor Protein P53
66 WNT Signaling 250 0.321
Genes names
  • Tumor Protein P53
67 MAPK signaling pathway 244 0.321
Genes names
  • Tumor Protein P53
68 mTOR Signaling 139 0.321
Genes names
  • Tumor Protein P53
69 Apoptosis and survival FAS signaling cascades 108 0.321
Genes names
  • P53-Induced Death Domain Protein 1
70 Hepatocyte growth factor receptor signaling 115 0.321
Genes names
  • Tumor Protein P53
71 APC-Cdc20 mediated degradation of Nek2A 50 0.321
Genes names
  • Tumor Protein P53
72 miRNAs involved in DNA damage response 67 0.321
Genes names
  • Tumor Protein P53
73 NGF Pathway 87 0.321
Genes names
  • Tumor Protein P53
74 Validated transcriptional targets of deltaNp63 isoforms 47 0.321
Genes names
  • P53 Apoptosis Effector Related To PMP22
75 Signaling events mediated by HDAC Class III 38 0.321
Genes names
  • Tumor Protein P53
76 Endometrial cancer 201 0.321
Genes names
  • Tumor Protein P53
77 Interleukin-1 family signaling 153 0.321
Genes names
  • Tumor Protein P53
78 MyD88 dependent cascade initiated on endosome 175 0.321
Genes names
  • Tumor Protein P53
79 fMLP Pathway 266 0.321
Genes names
  • Tumor Protein P53
80 GADD45 Pathway 32 0.321
Genes names
  • Tumor Protein P53
81 PI3K-Akt signaling pathway 390 0.321
Genes names
  • Tumor Protein P53
82 Keratinization 215 0.321
Genes names
  • P53 Apoptosis Effector Related To PMP22
83 IL-18 signaling pathway 50 0.321
Genes names
  • Tumor Protein P53
84 Chks in Checkpoint Regulation 186 0.321
Genes names
  • Tumor Protein P53
85 Defective Intrinsic Pathway for Apoptosis 25 0.321
Genes names
  • Tumor Protein P53
86 AP-1 transcription factor network 69 0.321
Genes names
  • Tumor Protein P53
87 Doxorubicin Pathway, Pharmacokinetics 28 0.321
Genes names
  • Tumor Protein P53
88 DNA damage response (only ATM dependent) 101 0.321
Genes names
  • Tumor Protein P53
89 DNA Damage Induced 14-3-3Sigma Signaling 19 0.321
Genes names
  • Tumor Protein P53
90 Glycolysis in senescence 8 0.321
Genes names
  • Tumor Protein P53
91 let-7 inhibition of ES cell reprogramming 21 0.321
Genes names
  • Tumor Protein P53
92 BARD1 signaling events 29 0.321
Genes names
  • Tumor Protein P53
93 Ovarian tumor domain proteases 39 0.321
Genes names
  • Tumor Protein P53
94 p70S6K Signaling 392 0.321
Genes names
  • Tumor Protein P53 Binding Protein 2
95 T-cell activation SARS-CoV-2 116 0.321
Genes names
  • Tumor Protein P53
96 Development EGFR signaling pathway 154 0.321
Genes names
  • Tumor Protein P53
97 Cyclins and Cell Cycle Regulation 72 0.321
Genes names
  • Tumor Protein P53
98 Caloric restriction and aging 9 0.321
Genes names
  • Tumor Protein P53
99 MAPK Signaling: Oxidative Stress 79 0.321
Genes names
  • Tumor Protein P53
100 Acyl chain remodelling of PE 46 0.321
Genes names
  • Tumor Protein P53
101 Formation of HIV elongation complex in the absence of HIV Tat 180 0.321
Genes names
  • Tumor Protein P53
102 Immune response IL-23 signaling pathway 160 0.321
Genes names
  • Tumor Protein P53
103 Pathogenesis of ALS 25 0.321
Genes names
  • Tumor Protein P53
104 TGF-Beta Pathway 653 0.321
Genes names
  • Tumor Protein P53
105 Gastric cancer network 2 31 0.321
Genes names
  • Tumor Protein P53
106 MAPK Pathway 88 0.321
Genes names
  • Tumor Protein P53
107 Thyroid hormones production and peripheral downstream signaling effects 83 0.321
Genes names
  • Tumor Protein P53
108 22q11.2 copy number variation syndrome 130 0.321
Genes names
  • Tumor Protein P53
109 CKAP4 signaling pathway map 108 0.321
Genes names
  • Tumor Protein P53
110 Regulation of TP53 Activity through Acetylation 30 0.321
Genes names
  • Tumor Protein P53
111 mTOR Pathway 58 0.321
Genes names
  • Tumor Protein P53
112 Packaging Of Telomere Ends 203 0.321
Genes names
  • Tumor Protein P53
113 TNFR1 Pathway 190 0.321
Genes names
  • Tumor Protein P53
114 Dopamine-DARPP32 Feedback onto cAMP Pathway 228 0.321
Genes names
  • Tumor Protein P53 Binding Protein 2
115 Cell cycle 137 0.321
Genes names
  • Tumor Protein P53
116 Epithelial to mesenchymal transition in colorectal cancer 161 0.321
Genes names
  • Tumor Protein P53
117 TP53 network 18 0.321
Genes names
  • Tumor Protein P53
118 Response to elevated platelet cytosolic Ca2+ 621 0.321
Genes names
  • Tumor Protein P53
119 Loss of function of TP53 in cancer due to loss of tetramerization ability 1 0.321
Genes names
  • Tumor Protein P53
120 Golgi-to-ER retrograde transport 369 0.321
Genes names
  • Tumor Protein P53
121 Cytokine Signaling in Immune system 732 0.321
Genes names
  • Tumor Protein P53
122 Chaperonin-mediated protein folding 97 0.321
Genes names
  • Tumor Protein P53
123 Genotoxicity pathway 60 0.321
Genes names
  • Tumor Protein P53 Inducible Protein 3
124 Pre-NOTCH Expression and Processing 235 0.321
Genes names
  • Tumor Protein P53
125 Inhibition of Ribosome Biogenesis by p14(ARF) 22 0.321
Genes names
  • Tumor Protein P53
126 Development IGF-1 receptor signaling 110 0.321
Genes names
  • Tumor Protein P53
127 ncRNAs involved in Wnt signaling in hepatocellular carcinoma 220 0.321
Genes names
  • Tumor Protein P53
128 Interleukin-4 and Interleukin-13 signaling 108 0.321
Genes names
  • Tumor Protein P53
129 Cell cycle Role of 14-3-3 proteins in cell cycle regulation 30 0.321
Genes names
  • Tumor Protein P53
130 Integrated breast cancer pathway 150 0.321
Genes names
  • Tumor Protein P53
131 p75(NTR)-mediated signaling 61 0.321
Genes names
  • Tumor Protein P53
132 Phospholipase-C Pathway 503 0.321
Genes names
  • Tumor Protein P53
133 Photodynamic therapy-induced HIF-1 survival signaling 37 0.321
Genes names
  • Tumor Protein P53
134 NF-kappaB Pathway 152 0.321
Genes names
  • Tumor Protein P53
135 Copper homeostasis 51 0.321
Genes names
  • Tumor Protein P53
136 Bladder cancer 40 0.321
Genes names
  • Tumor Protein P53
137 TCA cycle in senescence 10 0.321
Genes names
  • Tumor Protein P53
138 Nervous system development 1168 0.321
Genes names
  • P53 Apoptosis Effector Related To PMP22
139 Kynurenine pathway and links to cell senescence 27 0.321
Genes names
  • Tumor Protein P53
140 TP53 Regulates Metabolic Genes 87 0.321
Genes names
  • Tumor Protein P53
141 Head and neck squamous cell carcinoma 73 0.321
Genes names
  • Tumor Protein P53
142 Pentose phosphate pathway in senescent cells 5 0.321
Genes names
  • Tumor Protein P53
143 Hypoxic and oxygen homeostasis regulation of HIF-1-alpha 17 0.321
Genes names
  • Tumor Protein P53
144 NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence 17 0.321
Genes names
  • Tumor Protein P53
145 DYRK1A involvement regarding cell proliferation in brain development 62 0.321
Genes names
  • Tumor Protein P53
146 Transcription_P53 signaling pathway 54 0.321
Genes names
  • Tumor Protein P53
147 Retinoblastoma gene in cancer 86 0.321
Genes names
  • Tumor Protein P53
148 lncRNA-mediated mechanisms of therapeutic resistance 6 0.321
Genes names
  • Tumor Protein P53
149 Glucocorticoid receptor regulatory network 77 0.321
Genes names
  • Tumor Protein P53
150 Spinal cord injury 115 0.321
Genes names
  • Tumor Protein P53
151 Signal transduction_JNK pathway 44 0.321
Genes names
  • Tumor Protein P53
152 Netrin-UNC5B signaling pathway 52 0.321
Genes names
  • Tumor Protein P53
153 Burn wound healing 75 0.321
Genes names
  • Tumor Protein P53
154 Validated targets of C-MYC transcriptional activation 80 0.321
Genes names
  • Tumor Protein P53
155 Senescence and autophagy in cancer 105 0.321
Genes names
  • Tumor Protein P53
156 Prader-Willi and Angelman syndrome 60 0.321
Genes names
  • Tumor Protein P53
157 Signal Transduction 2590 0.321
Genes names
  • Tumor Protein P53
158 Ferroptosis 64 0.321
Genes names
  • Tumor Protein P53
159 SARS-CoV-2 innate immunity evasion and cell-specific immune response 50 0.321
Genes names
  • Tumor Protein P53 Inducible Protein 3
160 MicroRNA network associated with chronic lymphocytic leukemia 6 0.321
Genes names
  • Tumor Protein P53
161 RIPK1-mediated regulated necrosis 60 0.321
Genes names
  • Tumor Protein P53
162 Hair follicle development: cytodifferentiation - part 3 of 3 54 0.321
Genes names
  • P53 Apoptosis Effector Related To PMP22
163 Toll-like receptor signaling pathway 285 0.321
Genes names
  • Tumor Protein P53
164 Toll Comparative Pathway 101 0.321
Genes names
  • Tumor Protein P53
165 Metabolic reprogramming in pancreatic cancer 42 0.321
Genes names
  • Tumor Protein P53
166 Activation of cAMP-Dependent PKA 632 0.321
Genes names
  • Tumor Protein P53 Binding Protein 2
167 4-1BB Pathway 173 0.321
Genes names
  • Tumor Protein P53
168 Mammary gland development pathway - Involution (Stage 4 of 4) 10 0.321
Genes names
  • Tumor Protein P53
169 Infectious disease 1747 0.321
Genes names
  • Tumor Protein P53
170 Innate Immune System 2025 0.321
Genes names
  • Tumor Protein P53
171 Folate metabolism 11 0.321
Genes names
  • Tumor Protein P53
172 Androgen receptor network in prostate cancer 105 0.321
Genes names
  • Tumor Protein P53
173 Fluoropyrimidine activity 34 0.321
Genes names
  • Tumor Protein P53
174 Colorectal Cancer Metastasis 165 0.321
Genes names
  • Tumor Protein P53
175 Hepatitis C and hepatocellular carcinoma 55 0.321
Genes names
  • Tumor Protein P53
176 HIF1Alpha Pathway 54 0.321
Genes names
  • Tumor Protein P53
177 Loss of proteins required for interphase microtubule organization from the centrosome 226 0.321
Genes names
  • Tumor Protein P53
178 RNA Polymerase I Promoter Opening 509 0.321
Genes names
  • Tumor Protein P53