14-3-3 and Regulation of BAD Activity

No Pathway Network information available for 14-3-3 and Regulation of BAD Activity

Pathways in the 14-3-3 and Regulation of BAD Activity SuperPath

#	Name	Source	Genes
1	14-3-3 and Regulation of BAD Activity	QIAGEN	AKT1 BAD BAX BCL2 BCL2L1 BCL2L11 BEX3 CASP3 FOXO3 MAP3K5 NGF NGFR PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B TERT TNF TNFAIP3 TNFRSF1A TNFRSF1B TP73 YAP1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 32) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
2	BAD	BCL2 Associated Agonist Of Cell Death	Protein Coding	1
3	BAX	BCL2 Associated X, Apoptosis Regulator	Protein Coding	1
4	BCL2	BCL2 Apoptosis Regulator	Protein Coding	1
5	BCL2L1	BCL2 Like 1	Protein Coding	1
6	BCL2L11	BCL2 Like 11	Protein Coding	1
7	CASP3	Caspase 3	Protein Coding	1
8	FOXO3	Forkhead Box O3	Protein Coding	1
9	MAP3K5	Mitogen-Activated Protein Kinase Kinase Kinase 5	Protein Coding	1
10	NGF	Nerve Growth Factor	Protein Coding	1
11	NGFR	Nerve Growth Factor Receptor	Protein Coding	1
12	BEX3	Brain Expressed X-Linked 3	Protein Coding	1
13	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	1
14	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	1
15	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	1
16	PRKAR1A	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha	Protein Coding	1
17	PRKAR1B	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Beta	Protein Coding	1
18	PRKAR2A	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Alpha	Protein Coding	1
19	PRKAR2B	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Beta	Protein Coding	1
20	TERT	Telomerase Reverse Transcriptase	Protein Coding	1
21	TNF	Tumor Necrosis Factor	Protein Coding	1
22	TNFAIP3	TNF Alpha Induced Protein 3	Protein Coding	1
23	TNFRSF1A	TNF Receptor Superfamily Member 1A	Protein Coding	1
24	TNFRSF1B	TNF Receptor Superfamily Member 1B	Protein Coding	1
25	TP73	Tumor Protein P73	Protein Coding	1
26	YAP1	Yes1 Associated Transcriptional Regulator	Protein Coding	1
27	YWHAB	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Beta	Protein Coding	1
28	YWHAE	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon	Protein Coding	1
29	YWHAG	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Gamma	Protein Coding	1
30	YWHAH	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Eta	Protein Coding	1
31	YWHAQ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Theta	Protein Coding	1
32	YWHAZ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta	Protein Coding	1

Disorders associated with 14-3-3 and Regulation of BAD Activity SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Adrenocortical carcinoma	Enrichment	PRKAR1A, TERT	4.09
2	Kidney clear cell sarcoma	Enrichment	TERT, YWHAE	4.09
3	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	3.72
4	Meningioma	Enrichment	AKT1, TERT	3.46
5	Periodic fever, familial, autosomal dominant	Enrichment	TNFRSF1A	2.63
6	Proteus syndrome	Enrichment	AKT1	2.63
7	Acrodysostosis 1 with or without hormone resistance	Enrichment	PRKAR1A	2.63
8	Carney complex, type 1	Enrichment	PRKAR1A	2.63
9	Coloboma, ocular, with or without hearing impairment, cleft lip/palate, and/or impaired intellectual development	Enrichment	YAP1	2.63
10	Ciliary dyskinesia, primary, 47, and lissencephaly	Enrichment	TP73	2.63
11	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	2.63
12	Myxoma, intracardiac	Enrichment	PRKAR1A	2.63
13	Uveal coloboma-cleft lip and palate-intellectual disability	Enrichment	YAP1	2.63
14	Multiple sclerosis 5	Enrichment	TNFRSF1A	2.63
15	Cowden syndrome 6	Enrichment	AKT1	2.63
16	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	2.63
17	Developmental and epileptic encephalopathy 56	Enrichment	YWHAG	2.63
18	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	2.63
19	Tnf receptor-associated periodic fever syndrome	Enrichment	TNFRSF1A	2.63
20	Autosomal recessive dyskeratosis congenita 4	Enrichment	TERT	2.63
21	Familial behcet-like autoinflammatory syndrome	Enrichment	TNFAIP3	2.63
22	Prkar1b-related neurodegenerative dementia with intermediate filaments	Enrichment	PRKAR1B	2.63
23	Distal 17p13.3 microdeletion syndrome	Enrichment	YWHAE	2.63
24	Systemic lupus erythematosus	Enrichment	TNF, TNFAIP3	2.42
25	Amelogenesis imperfecta, type ig	Enrichment	PRKAR1A	2.33
26	Pigmented nodular adrenocortical disease, primary, 1	Enrichment	PRKAR1A	2.33
27	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	2.33
28	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 1	Enrichment	TERT	2.33
29	Autoinflammatory syndrome, familial, behcet-like 1	Enrichment	TNFAIP3	2.33
30	Marbach-schaaf neurodevelopmental syndrome	Enrichment	PRKAR1B	2.33
31	Usher syndrome, type iv	Enrichment	PRKAR1A	2.33
32	Intravascular large b-cell lymphoma	Enrichment	BCL2	2.33
33	Immunodeficiency 127	Enrichment	TNF	2.33
34	Acrodysostosis	Enrichment	PRKAR1A	2.33
35	Fibrolamellar carcinoma	Enrichment	PRKACA	2.33
36	Melanoma, cutaneous malignant 9	Enrichment	TERT	2.33
37	Ciliary dyskinesia, primary, 18	Enrichment	PRKAR1B	2.33
38	Idiopathic interstitial pneumonia	Enrichment	TERT	2.33
39	Intermittent hydrarthrosis	Enrichment	TNFRSF1A	2.33
40	Isolated primary pigmented nodular adrenocortical disease	Enrichment	PRKAR1A	2.33
41	Mycosis fungoides	Enrichment	TNFRSF1B	2.15
42	Psoriatic arthritis	Enrichment	TNF	2.15
43	Miller-dieker lissencephaly syndrome	Enrichment	YWHAE	2.15
44	Chromosome 17p13.3, centromeric, duplication syndrome	Enrichment	YWHAE	2.15
45	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	BCL2	2.15
46	Interstitial lung disease	Enrichment	TERT	2.15
47	Macrocytic anemia	Enrichment	TERT	2.15
48	T-cell acute lymphoblastic leukemia	Enrichment	BAX	2.15
49	Migraine without aura	Enrichment	TNF	2.15
50	Respiratory failure	Enrichment	TP73	2.15
51	Saczary syndrome	Enrichment	TNFRSF1B	2.15
52	Small cell cancer of the lung	Enrichment	TP73	2.03
53	Carney complex variant	Enrichment	PRKAR1A	2.03
54	Arrhythmogenic right ventricular dysplasia, familial, 10	Enrichment	PRKAR1A	2.03
55	Lung sarcomatoid carcinoma	Enrichment	TERT	2.03
56	Malignant epithelioid hemangioendothelioma	Enrichment	YAP1	2.03
57	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	YWHAZ	2.03
58	Cerebral malaria	Enrichment	TNF	2.03
59	Follicular lymphoma	Enrichment	BCL2	1.93
60	Vascular dementia	Enrichment	TNF	1.93
61	Endometrial stromal sarcoma	Enrichment	YWHAE	1.93
62	Idiopathic aplastic anemia	Enrichment	TERT	1.93
63	Dyskeratosis congenita, autosomal dominant 1	Enrichment	TERT	1.85
64	Pulmonary fibrosis	Enrichment	TERT	1.85
65	Hoyeraal-hreidarsson syndrome	Enrichment	TERT	1.85
66	Breast adenocarcinoma	Enrichment	AKT1	1.85
67	Neuropathy, hereditary sensory and autonomic, type v	Enrichment	NGF	1.79
68	Dyskeratosis congenita, autosomal dominant 2	Enrichment	TERT	1.79
69	Colorectal cancer	Enrichment	AKT1, BAX	1.75
70	Charge syndrome	Enrichment	TNFRSF1A	1.68
71	Cowden syndrome	Enrichment	AKT1	1.68
72	Aplastic anemia	Enrichment	TERT	1.63
73	Asthma	Enrichment	TNF	1.59
74	Specific learning disability	Enrichment	YWHAG	1.59
75	Microphthalmia/coloboma 12	Enrichment	YAP1	1.52
76	Acute promyelocytic leukemia	Enrichment	PRKAR1A	1.52
77	Alzheimer's disease	Enrichment	TNF	1.52
78	Multiple sclerosis	Enrichment	TNFRSF1A	1.49
79	Coloboma of macula	Enrichment	YAP1	1.46
80	Melanoma, cutaneous malignant 1	Enrichment	TERT	1.40
81	Interstitial lung disease 2	Enrichment	TERT	1.40
82	Behcet syndrome	Enrichment	TNFRSF1A	1.36
83	Dyskeratosis congenita	Enrichment	TERT	1.36
84	Hepatoblastoma	Enrichment	TERT	1.31
85	Hepatocellular carcinoma	Enrichment	TERT	1.30
86	Malaria	Enrichment	TNF	1.28
87	Autoinflammatory disease	Enrichment	TNFRSF1A	1.26
88	Bladder cancer	Enrichment	TERT	1.18
89	Differentiated thyroid carcinoma	Enrichment	TERT	1.18
90	Peripheral nervous system disease	Enrichment	NGF	1.14
91	Neuropathy	Enrichment	NGF	1.14
92	Leukemia, acute myeloid	Enrichment	TERT	1.04
93	Hereditary breast carcinoma	Enrichment	AKT1	1.01
94	Autosomal dominant non-syndromic intellectual disability	Enrichment	YWHAZ	0.95
95	Myeloma, multiple	Enrichment	YAP1	0.91
96	Undetermined early-onset epileptic encephalopathy	Enrichment	YWHAG	0.91
97	Breast cancer	Enrichment	AKT1	0.79
98	Primary ciliary dyskinesia	Enrichment	PRKAR1B	0.78
99	Ovarian cancer	Enrichment	AKT1	0.67
100	Microcephaly	Enrichment	YWHAG	0.60
101	Inherited cancer-predisposing syndrome	Enrichment	PRKAR1A	0.57

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

14-3-3 and Regulation of BAD Activity

Pathway Network for 14-3-3 and Regulation of BAD Activity

Member Pathways for 14-3-3 and Regulation of BAD Activity

Pathways in the 14-3-3 and Regulation of BAD Activity SuperPath

Associated Genes for 14-3-3 and Regulation of BAD Activity

Associated Disorders for 14-3-3 and Regulation of BAD Activity

Disorders associated with 14-3-3 and Regulation of BAD Activity SuperPath

STRING Interaction Network for 14-3-3 and Regulation of BAD Activity

Sources for 14-3-3 and Regulation of BAD Activity