2-Naphthylamine and 2-Nitronaphtalene metabolism

No Pathway Network information available for 2-Naphthylamine and 2-Nitronaphtalene metabolism

#	Name	Source	Genes
1	2-Naphthylamine and 2-Nitronaphtalene metabolism	GeneGo (Thomson Reuters)	CYP1A1 CYP1A2 CYP2B6 CYP2E1 CYP2F1 CYP3A4 EPHX1 GSTA1 GSTA2 GSTA3 GSTA4 GSTA5 SULT1A1 SULT1A2 SULT1A3 SULT1A4 UGT1A1 UGT1A3 UGT1A4 UGT1A6 UGT1A8 UGT1A9 (see all 22) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CYP1A1	Cytochrome P450 Family 1 Subfamily A Member 1	Protein Coding	1
2	CYP1A2	Cytochrome P450 Family 1 Subfamily A Member 2	Protein Coding	1
3	CYP2B6	Cytochrome P450 Family 2 Subfamily B Member 6	Protein Coding	1
4	CYP2E1	Cytochrome P450 Family 2 Subfamily E Member 1	Protein Coding	1
5	CYP2F1	Cytochrome P450 Family 2 Subfamily F Member 1	Protein Coding	1
6	CYP3A4	Cytochrome P450 Family 3 Subfamily A Member 4	Protein Coding	1
7	EPHX1	Epoxide Hydrolase 1	Protein Coding	1
8	GSTA1	Glutathione S-Transferase Alpha 1	Protein Coding	1
9	GSTA2	Glutathione S-Transferase Alpha 2	Protein Coding	1
10	GSTA3	Glutathione S-Transferase Alpha 3	Protein Coding	1
11	GSTA4	Glutathione S-Transferase Alpha 4	Protein Coding	1
12	SULT1A2	Sulfotransferase Family 1A Member 2	Protein Coding	1
13	SULT1A1	Sulfotransferase Family 1A Member 1	Protein Coding	1
14	SULT1A3	Sulfotransferase Family 1A Member 3	Protein Coding	1
15	UGT1A8	UDP Glucuronosyltransferase Family 1 Member A8	Protein Coding	1
16	UGT1A6	UDP Glucuronosyltransferase Family 1 Member A6	Protein Coding	1
17	UGT1A9	UDP Glucuronosyltransferase Family 1 Member A9	Protein Coding	1
18	UGT1A4	UDP Glucuronosyltransferase Family 1 Member A4	Protein Coding	1
19	UGT1A1	UDP Glucuronosyltransferase Family 1 Member A1	Protein Coding	1
20	UGT1A3	UDP Glucuronosyltransferase Family 1 Member A3	Protein Coding	1
21	GSTA5	Glutathione S-Transferase Alpha 5	Protein Coding	1
22	SULT1A4	Sulfotransferase Family 1A Member 4	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Crigler-najjar syndrome, type i	Enrichment	UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A8, UGT1A9	11.36
2	Hyperbilirubinemia, transient familial neonatal	Enrichment	UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A8, UGT1A9	11.36
3	Bilirubin, serum level of, quantitative trait locus 1	Enrichment	UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A8, UGT1A9	11.36
4	Crigler-najjar syndrome, type ii	Enrichment	UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A8, UGT1A9	11.36
5	Gilbert syndrome	Enrichment	UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A8, UGT1A9	10.76
6	Bilirubin metabolic disorder	Enrichment	UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A8, UGT1A9	10.76
7	Efavirenz, poor metabolism of	Enrichment	CYP2B6	2.79
8	Vitamin d-dependent rickets, type 3	Enrichment	CYP3A4	2.79
9	Genetic lipodystrophy	Enrichment	EPHX1	2.79
10	Familial hypercholanemia	Enrichment	EPHX1	2.01
11	Cystic fibrosis	Enrichment	EPHX1	1.30

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for 2-Naphthylamine and 2-Nitronaphtalene metabolism