5-aminoimidazole ribonucleotide biosynthesis
Pathways in the 5-aminoimidazole ribonucleotide biosynthesis SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | 5-aminoimidazole ribonucleotide biosynthesis | PubChem | |
| 2 | 5-aminoimidazole ribonucleotide biosynthesis I | PubChem |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | PPAT | Phosphoribosyl Pyrophosphate Amidotransferase | Protein Coding | 2 |
| 2 | PFAS | Phosphoribosylformylglycinamidine Synthase | Protein Coding | 2 |
| 3 | GART | Phosphoribosylglycinamide Formyltransferase, Phosphoribosylglycinamide Synthetase, Phosphoribosylaminoimidazole Synthetase | Protein Coding | 2 |
Disorders associated with 5-aminoimidazole ribonucleotide biosynthesis SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Cerebroretinal microangiopathy with calcifications and cysts 1 | Enrichment | PFAS | 3.18 |
| 2 | Isolated tracheo-esophageal fistula | Enrichment | GART | 2.66 |
| 3 | Esophageal atresia/tracheoesophageal fistula | Enrichment | GART | 2.38 |
| 4 | Dyskeratosis congenita | Enrichment | PFAS | 2.38 |
