Abacavir Pathway, Pharmacokinetics/Pharmacodynamics

No Pathway Network information available for Abacavir Pathway, Pharmacokinetics/Pharmacodynamics

#	Name	Source	Genes
1	Abacavir Pathway, Pharmacokinetics/Pharmacodynamics	PharmGKB	ADH1A ADH1B ADH1C ADK CKB CKM GUK1 NME1 NME2 PCK1 PGK1 PKLR PKM (see all 13) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	NME1	NME/NM23 Nucleoside Diphosphate Kinase 1	Protein Coding	1
2	NME2	NME/NM23 Nucleoside Diphosphate Kinase 2	Protein Coding	1
3	ADK	Adenosine Kinase	Protein Coding	1
4	GUK1	Guanylate Kinase 1	Protein Coding	1
5	PKLR	Pyruvate Kinase L/R	Protein Coding	1
6	PKM	Pyruvate Kinase M1/2	Protein Coding	1
7	PCK1	Phosphoenolpyruvate Carboxykinase 1	Protein Coding	1
8	PGK1	Phosphoglycerate Kinase 1	Protein Coding	1
9	ADH1A	Alcohol Dehydrogenase 1A (Class I), Alpha Polypeptide	Protein Coding	1
10	ADH1B	Alcohol Dehydrogenase 1B (Class I), Beta Polypeptide	Protein Coding	1
11	ADH1C	Alcohol Dehydrogenase 1C (Class I), Gamma Polypeptide	Protein Coding	1
12	CKB	Creatine Kinase B	Protein Coding	1
13	CKM	Creatine Kinase, M-Type	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Alcohol dependence	Enrichment	ADH1B, ADH1C	4.90
2	Adenosine triphosphate, elevated, of erythrocytes	Enrichment	PKLR	3.02
3	Anemia, congenital, nonspherocytic hemolytic, 2	Enrichment	PKLR	3.02
4	Phosphoenolpyruvate carboxykinase deficiency, cytosolic	Enrichment	PCK1	3.02
5	Phosphoglycerate kinase 1 deficiency	Enrichment	PGK1	3.02
6	Hypermethioninemia due to adenosine kinase deficiency	Enrichment	ADK	3.02
7	Male infertility due to obstructive azoospermia	Enrichment	PGK1	3.02
8	Mitochondrial dna depletion syndrome 21	Enrichment	GUK1	2.72
9	Phosphoenolpyruvate carboxykinase deficiency	Enrichment	PCK1	2.54
10	Parkinson disease, mitochondrial	Enrichment	ADH1C	2.42
11	Hemolytic anemia	Enrichment	PKLR	2.17
12	Parkinson disease, late-onset	Enrichment	ADH1C	1.64

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Abacavir Pathway, Pharmacokinetics/Pharmacodynamics