Abiraterone Pathway, Pharmacokinetics
Pathways in the Abiraterone Pathway, Pharmacokinetics SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Abiraterone Pathway, Pharmacokinetics | PharmGKB |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | SULT2A1 | Sulfotransferase Family 2A Member 1 | Protein Coding | 1 |
| 2 | UGT1A4 | UDP Glucuronosyltransferase Family 1 Member A4 | Protein Coding | 1 |
| 3 | HSD3B1 | Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- And Steroid Delta-Isomerase 1 | Protein Coding | 1 |
| 4 | HSD3B2 | Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- And Steroid Delta-Isomerase 2 | Protein Coding | 1 |
| 5 | CYP3A4 | Cytochrome P450 Family 3 Subfamily A Member 4 | Protein Coding | 1 |
| 6 | SLCO2B1 | Solute Carrier Organic Anion Transporter Family Member 2B1 | Protein Coding | 1 |
Disorders associated with Abiraterone Pathway, Pharmacokinetics SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Vitamin d-dependent rickets, type 3 | Enrichment | CYP3A4 | 3.35 |
| 2 | Adrenal hyperplasia, congenital, due to 3-beta-hydroxysteroid dehydrogenase 2 deficiency | Enrichment | HSD3B2 | 3.05 |
| 3 | Hypospadias 1, x-linked | Enrichment | HSD3B2 | 3.05 |
| 4 | 3 beta-hydroxysteroid dehydrogenase deficiency | Enrichment | HSD3B2 | 3.05 |
| 5 | Crigler-najjar syndrome, type i | Enrichment | UGT1A4 | 2.35 |
| 6 | Hyperbilirubinemia, transient familial neonatal | Enrichment | UGT1A4 | 2.35 |
| 7 | Bilirubin, serum level of, quantitative trait locus 1 | Enrichment | UGT1A4 | 2.35 |
| 8 | Crigler-najjar syndrome, type ii | Enrichment | UGT1A4 | 2.35 |
| 9 | Gilbert syndrome | Enrichment | UGT1A4 | 2.31 |
| 10 | Bilirubin metabolic disorder | Enrichment | UGT1A4 | 2.31 |
| 11 | Lipoid congenital adrenal hyperplasia | Enrichment | HSD3B2 | 2.21 |
