Acetylcholine synthesis

No Pathway Network information available for Acetylcholine synthesis

#	Name	Source	Genes
1	Acetylcholine synthesis	WikiPathways	ACHE CHAT CHKA PCYT1A PDHA1 PDHA2 PEMT (see all 7) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PDHA2	Pyruvate Dehydrogenase E1 Subunit Alpha 2	Protein Coding	1
2	PDHA1	Pyruvate Dehydrogenase E1 Subunit Alpha 1	Protein Coding	1
3	PCYT1A	Phosphate Cytidylyltransferase 1A, Choline	Protein Coding	1
4	ACHE	Acetylcholinesterase (Yt Blood Group)	Protein Coding	1
5	CHKA	Choline Kinase Alpha	Protein Coding	1
6	CHAT	Choline O-Acetyltransferase	Protein Coding	1
7	PEMT	Phosphatidylethanolamine N-Methyltransferase	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Apnea, central sleep	Enrichment	CHAT	3.29
2	Yt blood group antigen	Enrichment	ACHE	3.29
3	Neurodevelopmental disorder with microcephaly, movement abnormalities, and seizures	Enrichment	CHKA	3.29
4	Spermatogenic failure 70	Enrichment	PDHA2	3.29
5	Aspiration pneumonia	Enrichment	CHAT	3.29
6	Spondylometaphyseal dysplasia with cone-rod dystrophy	Enrichment	PCYT1A	2.99
7	Myasthenic syndrome, congenital, 21, presynaptic	Enrichment	CHAT	2.99
8	Lipodystrophy, congenital generalized, type 5	Enrichment	PCYT1A	2.99
9	Myasthenic syndrome, congenital, 6, presynaptic	Enrichment	CHAT	2.81
10	Bronchopulmonary dysplasia	Enrichment	CHAT	2.81
11	Pyruvate dehydrogenase e1-alpha deficiency	Enrichment	PDHA1	2.69
12	Spermatogenic failure 1	Enrichment	PDHA2	2.69
13	Gastroesophageal reflux	Enrichment	CHAT	2.38
14	Myasthenic syndrome, congenital, 4c, associated with acetylcholine receptor deficiency	Enrichment	CHAT	2.29
15	Presynaptic congenital myasthenic syndromes	Enrichment	CHAT	2.25
16	Lactic acidosis	Enrichment	CHAT	2.21
17	Congenital myasthenic syndrome	Enrichment	CHAT	2.14
18	Sudden infant death syndrome	Enrichment	PDHA1	2.06
19	Azoospermia	Enrichment	PDHA2	1.99
20	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	PDHA2	1.54
21	Autosomal recessive non-syndromic intellectual disability	Enrichment	CHKA	1.53
22	Leber plus disease	Enrichment	PCYT1A	1.32
23	Microcephaly	Enrichment	CHKA	1.21

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Acetylcholine synthesis