Ac/N-end rule pathway

No Pathway Network information available for Ac/N-end rule pathway

#	Name	Source	Genes
1	Ac/N-end rule pathway	PubChem	METAP1 METAP2 NAA10 NAA15 NAA20 NAA25 NAA30 NAA35 NAA38 NAA50 (see all 10) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	NAA15	N-Alpha-Acetyltransferase 15, NatA Auxiliary Subunit	Protein Coding	1
2	NAA50	N-Alpha-Acetyltransferase 50, NatE Catalytic Subunit	Protein Coding	1
3	NAA25	N-Alpha-Acetyltransferase 25, NatB Auxiliary Subunit	Protein Coding	1
4	NAA20	N-Alpha-Acetyltransferase 20, NatB Catalytic Subunit	Protein Coding	1
5	NAA10	N-Alpha-Acetyltransferase 10, NatA Catalytic Subunit	Protein Coding	1
6	METAP1	Methionyl Aminopeptidase 1	Protein Coding	1
7	METAP2	Methionyl Aminopeptidase 2	Protein Coding	1
8	NAA30	N-Alpha-Acetyltransferase 30, NatC Catalytic Subunit	Protein Coding	1
9	NAA38	N-Alpha-Acetyltransferase 38, NatC Auxiliary Subunit	Protein Coding	1
10	NAA35	N-Alpha-Acetyltransferase 35, NatC Auxiliary Subunit	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Intellectual developmental disorder, autosomal recessive 73	Enrichment	NAA20	3.13
2	Intellectual developmental disorder, autosomal dominant 50, with behavioral abnormalities	Enrichment	NAA15	3.13
3	Ogden syndrome	Enrichment	NAA10	2.83
4	Microphthalmia, syndromic 1	Enrichment	NAA10	2.83
5	Autosomal recessive non-syndromic intellectual disability	Enrichment	NAA20	1.38
6	Autism	Enrichment	NAA15	1.29
7	Complex neurodevelopmental disorder	Enrichment	NAA15	1.06

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Ac/N-end rule pathway