Acquired partial lipodystrophy / Barraquer-Simons syndrome

No Pathway Network information available for Acquired partial lipodystrophy / Barraquer-Simons syndrome

Pathways in the Acquired partial lipodystrophy / Barraquer-Simons syndrome SuperPath

#	Name	Source	Genes
1	Acquired partial lipodystrophy / Barraquer-Simons syndrome	WikiPathways	C3 C5 CFB CFD FNTA ICMT LMNA LMNB1 LMNB2 RCE1 (see all 10) (see less)
2	Breakdown of the nuclear lamina	Reactome	LMNA LMNB1

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	LMNB1	Lamin B1	Protein Coding	2
2	LMNA	Lamin A/C	Protein Coding	2
3	LMNB2	Lamin B2	Protein Coding	1
4	C5	Complement C5	Protein Coding	1
5	C3	Complement C3	Protein Coding	1
6	CFB	Complement Factor B	Protein Coding	1
7	CFD	Complement Factor D	Protein Coding	1
8	RCE1	Ras Converting CAAX Endopeptidase 1	Protein Coding	1
9	ICMT	Isoprenylcysteine Carboxyl Methyltransferase	Protein Coding	1
10	FNTA	Farnesyltransferase, CAAX Box, Subunit Alpha	Protein Coding	1

Disorders associated with Acquired partial lipodystrophy / Barraquer-Simons syndrome SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Atypical hemolytic uremic syndrome with complement gene abnormality	Enrichment	C3, CFB	5.14
2	Leukodystrophy, demyelinating, adult-onset, autosomal dominant, typical	Enrichment	LMNB1	3.83
3	Adult onset demyelinating leukodystrophy	Enrichment	LMNB1	3.83
4	Microcephaly 26, primary, autosomal dominant	Enrichment	LMNB1	3.83
5	Atypical werner syndrome	Enrichment	LMNA	3.83
6	Mandibuloacral dysplasia	Enrichment	LMNA	3.83
7	Atrioventricular block	Enrichment	LMNA	3.83
8	Lmna-related cardiocutaneous progeria syndrome	Enrichment	LMNA	3.83
9	Autosomal semi-dominant severe lipodystrophic laminopathy	Enrichment	LMNA	3.83
10	Autosomal recessive axonal hereditary motor and sensory neuropathy	Enrichment	LMNA	3.83
11	Laminopathy	Enrichment	LMNA	3.83
12	Mandibuloacral dysplasia with type a lipodystrophy	Enrichment	LMNA	3.53
13	Heart-hand syndrome, slovenian type	Enrichment	LMNA	3.53
14	Charcot-marie-tooth disease, axonal, type 2b1	Enrichment	LMNA	3.53
15	Cardiomyopathy, dilated, with hypergonadotropic hypogonadism	Enrichment	LMNA	3.53
16	Cardiomyopathy, dilated, 1d	Enrichment	LMNA	3.53
17	Restrictive dermopathy 2	Enrichment	LMNA	3.53
18	Emery-dreifuss muscular dystrophy 3, autosomal recessive	Enrichment	LMNA	3.53
19	Lipodystrophy, familial partial, type 1	Enrichment	LMNA	3.53
20	Autosomal dominant primary microcephaly	Enrichment	LMNB1	3.53
21	Familial partial lipodystrophy	Enrichment	LMNA	3.53
22	Charcot-marie-tooth disease type 2b1	Enrichment	LMNA	3.53
23	Restrictive dermopathy 1	Enrichment	LMNA	3.35
24	Lipodystrophy, familial partial, type 2	Enrichment	LMNA	3.35
25	Muscular dystrophy, congenital, lmna-related	Enrichment	LMNA	3.35
26	Restrictive dermopathy	Enrichment	LMNA	3.35
27	Hutchinson-gilford progeria syndrome	Enrichment	LMNA	3.23
28	Emery-dreifuss muscular dystrophy 1, x-linked	Enrichment	LMNA	3.23
29	Microtia-anotia	Enrichment	LMNA	3.23
30	Emery-dreifuss muscular dystrophy	Enrichment	LMNA	3.23
31	Sick sinus syndrome	Enrichment	LMNA	3.23
32	Autosomal recessive limb-girdle muscular dystrophy type 2b	Enrichment	LMNA	3.13
33	Histiocytoid hemangioma	Enrichment	LMNA	3.13
34	Complement component 5 deficiency	Enrichment	C5	3.13
35	Hemolytic uremic syndrome, atypical 4	Enrichment	CFB	3.13
36	Complement factor d deficiency	Enrichment	CFD	3.13
37	Hemolytic uremic syndrome, atypical 5	Enrichment	C3	3.13
38	Eculizumab, poor response to	Enrichment	C5	3.13
39	Epilepsy, progressive myoclonic, 9	Enrichment	LMNB2	3.13
40	Lipodystrophy, partial, acquired	Enrichment	LMNB2	3.13
41	Macular degeneration, age-related, 9	Enrichment	C3	3.13
42	Complement component 3 deficiency, autosomal recessive	Enrichment	C3	3.13
43	Complement factor b deficiency	Enrichment	CFB	3.13
44	Microcephaly 27, primary, autosomal dominant	Enrichment	LMNB2	3.13
45	Complement component 3 deficiency	Enrichment	C3	3.13
46	Membranoproliferative glomerulonephritis	Enrichment	C3	3.13
47	Primary membranoproliferative glomerulonephritis	Enrichment	C3	3.13
48	Recurrent neisseria infections due to factor d deficiency	Enrichment	CFD	3.13
49	Emery-dreifuss muscular dystrophy 2, autosomal dominant	Enrichment	LMNA	3.05
50	Bethlem myopathy 1a	Enrichment	LMNA	2.99
51	Congenital muscular dystrophy	Enrichment	LMNA	2.93
52	Myocarditis	Enrichment	LMNA	2.93
53	Arrhythmogenic right ventricular dysplasia, familial, 9	Enrichment	LMNA	2.88
54	Cyclic neutropenia	Enrichment	CFD	2.83
55	Lipomatosis, multiple symmetric, with or without axonal peripheral neuropathy	Enrichment	LMNB2	2.83
56	Lathosterolosis	Enrichment	C5	2.83
57	Macular degeneration, age-related, 14	Enrichment	CFB	2.83
58	Cardiac conduction defect	Enrichment	LMNA	2.75
59	Muscular dystrophy, limb-girdle, autosomal recessive 2	Enrichment	LMNA	2.75
60	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	LMNA	2.75
61	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	LMNA	2.75
62	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	LMNA	2.69
63	Neutropenia, severe congenital, 1, autosomal dominant	Enrichment	CFD	2.66
64	Genetic atypical hemolytic-uremic syndrome	Enrichment	C3	2.66
65	Arrhythmogenic right ventricular cardiomyopathy	Enrichment	LMNA	2.63
66	Cardiomyopathy, dilated, 1e	Enrichment	LMNA	2.60
67	Neuromuscular disease	Enrichment	LMNA	2.58
68	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	LMNA	2.55
69	Cardiomyopathy, dilated, 1a	Enrichment	LMNA	2.51
70	Cardiomyopathy, familial hypertrophic, 1	Enrichment	LMNA	2.45
71	Muscular dystrophy	Enrichment	LMNA	2.45
72	Brugada syndrome	Enrichment	LMNA	2.42
73	Long qt syndrome	Enrichment	LMNA	2.34
74	Peripheral nervous system disease	Enrichment	LMNA	2.33
75	Neuropathy	Enrichment	LMNA	2.33
76	Immunodeficiency due to a late component of complement deficiency	Enrichment	C5	2.29
77	Left ventricular noncompaction	Enrichment	LMNA	2.29
78	Charcot-marie-tooth disease	Enrichment	LMNA	2.22
79	Familial isolated dilated cardiomyopathy	Enrichment	LMNA	2.11
80	Atypical hemolytic-uremic syndrome	Enrichment	C3	1.96
81	Dilated cardiomyopathy	Enrichment	LMNA	1.93

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Acquired partial lipodystrophy / Barraquer-Simons syndrome

Pathway Network for Acquired partial lipodystrophy / Barraquer-Simons syndrome

Member Pathways for Acquired partial lipodystrophy / Barraquer-Simons syndrome

Pathways in the Acquired partial lipodystrophy / Barraquer-Simons syndrome SuperPath

Associated Genes for Acquired partial lipodystrophy / Barraquer-Simons syndrome

Associated Disorders for Acquired partial lipodystrophy / Barraquer-Simons syndrome

Disorders associated with Acquired partial lipodystrophy / Barraquer-Simons syndrome SuperPath

STRING Interaction Network for Acquired partial lipodystrophy / Barraquer-Simons syndrome

Sources for Acquired partial lipodystrophy / Barraquer-Simons syndrome