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Activated TLR4 signalling SuperPath

Pathway network for Activated TLR4 signalling SuperPath
31 Pathways in the Activated TLR4 signalling SuperPath
Regulation of TLR by endogenous ligand TRIF-mediated TLR3/TLR4 signaling
TRIF-mediated programmed cell death Toll-Like Receptors Cascades
TICAM1 deficiency - HSE MyD88 cascade initiated on plasma membrane
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation Toll Like Receptor 10 (TLR10) Cascade
MyD88 dependent cascade initiated on endosome Toll Like Receptor TLR6-TLR2 Cascade
TRAF6 mediated induction of TAK1 complex activated TAK1 mediates p38 MAPK activation
MAP kinase activation in TLR cascade Toll Like Receptor TLR1-TLR2 Cascade
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 MyD88-Mal cascade initiated on plasma membrane
Toll Like Receptor 2 (TLR2) Cascade TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
IRAK2 mediated activation of TAK1 complex Toll Like Receptor 9 (TLR9) Cascade
Trafficking and processing of endosomal TLR Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
TRAF3 deficiency - HSE TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
Toll Like Receptor 5 (TLR5) Cascade Toll Like Receptor 7/8 (TLR7/8) Cascade
Toll Like Receptor 4 (TLR4) Cascade Transfer of LPS from LBP carrier to CD14
MyD88-independent TLR3/TLR4 cascade Toll Like Receptor 3 (TLR3) Cascade
Activated TLR4 signalling
153 Genes in the Activated TLR4 signalling SuperPath
TRAF6 IRAK2 MAP3K7 TAB1 TAB2 TAB3 RPS27A UBA52 UBB UBC IRAK1 UBE2N
UBE2V1 MIR718 CD14 IKBKG RIPK2 NOD1 NOD2 TLR4 LY96 MAPK14 MAPK8 MAPK11
MAPK9 MAPK10 MAP2K3 MAP2K6 MAP2K7 MAP2K4 MAPKAPK3 MAPKAPK2 HMGB1 ATF1 CHUK MAP3K8
CREB1 ATF2 DUSP3 DUSP4 DUSP6 DUSP7 ELK1 FOS IKBKB JUN MEF2A MEF2C
MYD88 NFKB1 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D MAPK1 MAPK3 MAPK7 MAP2K1 RPS6KA1
RPS6KA2 RPS6KA3 SKP1 CUL1 BTRC RPS6KA5 FBXW11 VRK3 TNIP2 AGER APP DHX9
NFKB2 NFKBIA NFKBIB RELA S100A12 S100B SAA1 TLR3 TICAM1 IRAK4 TICAM2 MAP3K1
ECSIT PELI2 PELI1 PELI3 IRF7 CD36 TLR1 TLR2 TLR6 TRAF3 SARM1 CASP8
IRF3 PTPN11 RIPK1 FADD IKBKE TANK RIPK3 TBK1 BTK SOCS1 IRAK3 TLR7
TLR8 TLR9 SIGIRR TIRAP MIR6502 BIRC2 BIRC3 UBE2D1 UBE2D2 UBE2D3 DHX36 LBP
TLR5 TLR10 APOB FGA FGB FGG S100A1 S100A8 S100A9 BPI CTSB CTSK
CTSL CTSV CTSS DNM1 DNM2 ITGAM ITGB2 CD180 PIK3C3 PLCG2 LGMN PTPN4
HSP90B1 EEA1 LY86 CNPY3 DNM3 PIK3R4 RBSN UNC93B1 MIR3652
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network for Activated TLR4 signalling SuperPath