Activation of cAMP-Dependent PKA

Pathway network for the Activation of cAMP-Dependent PKA SuperPath

Sources:

QIAGEN

Pathways in the Activation of cAMP-Dependent PKA SuperPath

#	Name	Source	Genes
1	Activation of cAMP-Dependent PKA	QIAGEN	ADCY1 ADCY10 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADD1 ADD2 ADD3 ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 AKAP1 AKAP10 AKAP11 AKAP12 AKAP13 AKAP3 AKAP4 AKAP5 AKAP6 AKAP7 AKAP8 AKAP9 ALK ANGPTL6 AREG ATF1 ATF4 AXL BAD BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BRAF BTC CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 CALM1 CALM2 CALM3 CAMK1 CAMK1G CAMK2A CAMK2B CAMK2D CAMK2G CAMK4 CCN2 CLCA1 CLCA2 CLCA3P CLCA4 CLCN1 CLCN2 CLCN3 CLCN4 CLCN5 CLCN6 CLCN7 CLCNKA CLCNKB CLEC11A CLEC18C CLIC1 CLIC2 CLIC3 CLIC4 CLIC5 CLIC6 CLNS1A CNGA1 CNGA3 CNGA4 CNGB1 CNGB3 CREB1 CREB3 CREB3L4 CREBBP CREM CRHR1 CRHR2 CRIPTO CRP CSF1R CXCL12 DDR1 DDR2 DRC4 EGF EGFR ELK1 EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPOR ERBB2 ERBB3 ERBB4 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 GAS1 GAS2 GAS6 GCG GCGR GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GMFG GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GNRH1 GNRH2 GPC6 GRB2 GRK1 GRK7 GSK3A GSK3B GYS1 GYS2 HDGF HGF HRAS IGF1 IGF1R IGF2 IGF2-AS IL2 IL3 IL6 IL9 INSR INSRR ITPR1 ITPR2 ITPR3 KCMF1 KCNK1 KCNK10 KCNK12 KCNK13 KCNK15 KCNK16 KCNK17 KCNK2 KCNK3 KCNK4 KCNK5 KCNK6 KCNK7 KCNK9 KCNRG KCNT1 KCNT2 KCNU1 KCNV1 KCNV2 KCTD1 KCTD10 KCTD11 KCTD12 KCTD13 KCTD14 KCTD15 KCTD2 KCTD3 KCTD4 KCTD5 KCTD6 KCTD7 KCTD8 KCTD9 KDELR1 KDELR2 KDELR3 KDR KIT KITLG KLF10 KRAS LEFTY1 LEFTY2 LHB LIFR LIPE LMTK2 LMTK3 LTBP1 LTBP2 LTBP3 LTBP4 MAP2K1 MAP2K2 MAPK1 MAPK3 MDK MERTK MET MRAS MST1R MUSK MYL1 MYL11 MYL2 MYL3 MYL4 MYL5 MYL6 MYL7 MYL9 NFAT5 NFATC1 NFATC2 NFATC3 NFATC4 NFKB1 NGF NOS3 NRAS NRG1 NRG2 NRG3 NTF3 NTF4 NTN1 NTRK1 NTRK2 NTRK3 NUDT6 OGN PDE1A PDE1B PDE1C PDE2A PDE3A PDE3B PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PHKA1 PHKA2 PHKB PHKG1 PHKG2 PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PLN PLPP3 PPBP PPP1R10 PPP1R11 PPP1R12A PPP1R12B PPP1R12C PPP1R13B PPP1R14A PPP1R14B PPP1R15A PPP1R16A PPP1R1A PPP1R1B PPP1R2 PPP1R3A PPP1R3B PPP1R3C PPP1R3D PPP1R3F PPP1R7 PPP1R8 PPP1R9A PPP1R9B PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCQ PRKD1 PRKD3 PROK1 PSIP1 PTK7 PTN PTPN1 PTPN2 PTPN3 PTPRA PTPRB PTPRC PYGB PYGL PYGM RAF1 RAP1A RAP1B RHOA ROCK1 ROCK2 ROR1 ROR2 ROS1 RRAS RRAS2 RYK RYR1 RYR2 RYR3 SCN10A SCN11A SCN1A SCN1B SCN2A SCN2B SCN3A SCN3B SCN4A SCN4B SCN5A SCN7A SCN8A SCN9A SCNN1A SCNN1B SCNN1D SCNN1G SEMA3A SEMA4B SEMA4G SEMA5A SOS1 SOS2 SPON1 TBRG1 TEK TGFA TGFB1 TGFB2 TGFB3 THPO TIE1 TIMP1 TIMP2 TIMP3 TIMP4 TNNI1 TNNI2 TNNI3 TP53BP2 TYMP TYRO3 UCN UTS2 VASP VEGFB VEGFC VEGFD YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 501) (see less)
2	cAMP Pathway	QIAGEN	ADCY1 ADCY10 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADD1 ADD2 ADD3 ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 AKAP1 AKAP10 AKAP11 AKAP12 AKAP13 AKAP3 AKAP4 AKAP5 AKAP6 AKAP7 AKAP8 AKAP9 AKT1 AKT2 AKT3 ANAPC1 ANAPC10 ANAPC11 ANAPC13 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ANGPTL6 AREG ARRB1 ARRB2 ATF1 ATF4 BAD BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BRAF BTC CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 CALM1 CALM2 CALM3 CAMK1 CAMK1G CAMK2A CAMK2B CAMK2D CAMK2G CAMK4 CCN2 CDC16 CDC23 CDC27 CDK16 CLCA1 CLCA2 CLCA3P CLCA4 CLCN1 CLCN2 CLCN3 CLCN4 CLCN5 CLCN6 CLCN7 CLEC11A CLEC14A CLEC18C CLIC1 CLIC2 CLIC3 CLIC4 CLIC5 CLIC6 CLNS1A CNGA1 CNGA3 CNGA4 CNGB1 CNGB3 CREB1 CREB3 CREB3L4 CREBBP CREM CRHR1 CRHR2 CRIPTO CRP CXCL12 DCC DRC4 EGF EGFR ELK1 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 GAS1 GAS2 GAS6 GCG GCGR GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLG1 GMFG GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAT1 GNAT2 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GNRH1 GNRH2 GPC6 GSK3A GSK3B GYS1 GYS2 HBEGF HDGF HGF HRAS IGF1 IGF1R IGF2 IGF2-AS IGF2R IL2 IL2RA IL3 IL6 IL9 ITPR1 ITPR2 ITPR3 KCMF1 KCNK1 KCNK10 KCNK12 KCNK13 KCNK15 KCNK16 KCNK17 KCNK2 KCNK3 KCNK4 KCNK5 KCNK6 KCNK7 KCNK9 KCNRG KCNT1 KCNT2 KCNU1 KCNV1 KCNV2 KCTD1 KCTD10 KCTD11 KCTD12 KCTD13 KCTD14 KCTD15 KCTD2 KCTD3 KCTD4 KCTD5 KCTD6 KCTD7 KCTD8 KCTD9 KDELR1 KDELR2 KDELR3 KDR KIT KITLG KLF10 KRAS LEFTY1 LEFTY2 LHB LIPE LTBP1 LTBP2 LTBP3 LTBP4 MAP2K1 MAP2K2 MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK6 MAPK7 MDK MEP1B MET MRAS MTOR MYL1 MYL11 MYL2 MYL3 MYL4 MYL5 MYL6 MYL7 MYL9 NFAT5 NFATC1 NFATC2 NFATC3 NFATC4 NFKB1 NGF NGFR NOS3 NRAS NRG1 NRG2 NRG3 NRP1 NRP2 NTF3 NTF4 NTN1 NTRK1 NTRK2 NTRK3 NUDT6 OGFR OGN PDE1A PDE1B PDE1C PDE2A PDE3A PDE3B PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PHKA1 PHKA2 PHKB PHKG1 PHKG2 PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PKIA PKIB PKIG PLA2G10 PLA2G12A PLA2G12B PLA2G1B PLA2G2A PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4C PLA2G4D PLA2G5 PLA2G6 PLA2G7 PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PLN PLPP3 PPBP PPP1R10 PPP1R11 PPP1R12A PPP1R12B PPP1R12C PPP1R13B PPP1R14A PPP1R14B PPP1R15A PPP1R16A PPP1R1A PPP1R1B PPP1R2 PPP1R3A PPP1R3B PPP1R3C PPP1R3D PPP1R3F PPP1R7 PPP1R8 PPP1R9A PPP1R9B PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCQ PRKD1 PRKD3 PROK1 PSIP1 PTK2B PTN PTPN1 PTPN2 PTPN3 PTPRA PTPRB PTPRC PYGB PYGL PYGM RAF1 RAP1A RAP2A RAPGEF4 RGS1 RGS10 RGS11 RGS12 RGS13 RGS14 RGS16 RGS17 RGS18 RGS19 RGS2 RGS20 RGS21 RGS22 RGS3 RGS4 RGS5 RGS6 RGS7 RGS8 RGS9 RHOA ROCK1 ROCK2 RPS6KB1 RRAS RRAS2 RYR1 RYR2 RYR3 SCN10A SCN11A SCN1A SCN1B SCN2A SCN2B SCN3A SCN3B SCN4A SCN4B SCN5A SCN7A SCN8A SCN9A SCNN1A SCNN1B SCNN1D SCNN1G SEMA3A SEMA4B SEMA4G SEMA5A SPON1 SRC TBRG1 TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TNNI1 TNNI2 TNNI3 TP53BP2 TYMP UCN UTS2 VEGFB VEGFC VEGFD YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 542) (see less)
3	Activation of PKA through GPCR	QIAGEN	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADD1 ADD2 ADD3 ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 AKAP1 AKAP10 AKAP11 AKAP12 AKAP13 AKAP3 AKAP4 AKAP5 AKAP6 AKAP7 AKAP8 AKAP9 ALK ANAPC1 ANAPC10 ANAPC11 ANAPC13 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ANGPTL6 AREG ATF1 ATF4 AXL BAD BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BRAF BTC CCN2 CDC16 CDC23 CDC27 CDK16 CHUK CLEC11A CLEC18C CREB1 CREB3 CREB3L4 CREBBP CREM CRIPTO CRP CSF1R CXCL12 DDR1 DDR2 DHH DRC4 EGFR ELK1 EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPOR ERBB2 ERBB3 ERBB4 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 GAS1 GAS2 GAS6 GCG GCGR GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLI1 GMFG GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAT1 GNAT2 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GNRH1 GNRH2 GPC6 GRK1 GRK7 GSK3A GSK3B GYS1 GYS2 HDGF HGF HRAS IGF1 IGF1R IGF2 IHH IL2 IL3 IL6 IL9 INSR INSRR ITPR1 ITPR2 ITPR3 KDELR1 KDELR2 KDELR3 KDR KIT KITLG KLF10 KRAS LEFTY1 LEFTY2 LHB LIFR LIPE LMTK2 LMTK3 LTBP1 LTBP2 LTBP3 LTBP4 MAP2K1 MAP2K2 MAPK1 MAPK3 MDK MERTK MET MRAS MST1R MUSK MYL1 MYL11 MYL2 MYL3 MYL4 MYL5 MYL6 MYL7 MYL9 NFAT5 NFATC1 NFATC2 NFATC3 NFATC4 NFKB1 NFKBIA NFKBIB NFKBIE NGF NOS3 NRAS NRG1 NRG2 NRG3 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGN PDE1A PDE1B PDE1C PDE2A PDE3A PDE3B PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PLN PLPP3 PPBP PPP1R10 PPP1R11 PPP1R12A PPP1R12B PPP1R12C PPP1R13B PPP1R14A PPP1R14B PPP1R15A PPP1R16A PPP1R1A PPP1R1B PPP1R2 PPP1R3A PPP1R3B PPP1R3C PPP1R3D PPP1R3F PPP1R7 PPP1R8 PPP1R9A PPP1R9B PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCQ PRKD1 PRKD3 PROK1 PSIP1 PTCH1 PTCH2 PTK7 PTN PTPN1 PTPN2 PTPN3 PTPRA PTPRB PTPRC PYGB PYGL PYGM RAF1 RAP1A RAP1B RHOA ROCK1 ROCK2 ROR1 ROR2 ROS1 RRAS RRAS2 RYK RYR1 RYR2 RYR3 SEMA3A SEMA4B SEMA4G SEMA5A SMO SPON1 SRC STK36 SUFU TBRG1 TEK TGFA TGFB1 TGFB2 TGFB3 THPO TIE1 TIMP1 TIMP2 TIMP3 TIMP4 TNNI1 TNNI2 TNNI3 TP53BP2 TYMP TYRO3 UCN UTS2 VASP VEGFB VEGFC VEGFD YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 399) (see less)
4	PKA Signaling	QIAGEN	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADD1 ADD2 ADD3 AKAP1 AKAP10 AKAP11 AKAP12 AKAP13 AKAP3 AKAP4 AKAP5 AKAP6 AKAP7 AKAP8 AKAP9 ATF1 ATF4 BAD BRAF CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 CALM1 CALM2 CALM3 CAMK4 CHUK CLCA1 CLCA2 CLCA3P CLCA4 CLCN1 CLCN2 CLCN3 CLCN4 CLCN5 CLCN6 CLCN7 CLEC18C CLIC1 CLIC2 CLIC3 CLIC4 CLIC5 CLIC6 CLNS1A CNGA1 CNGA3 CNGA4 CNGB1 CNGB3 CREB1 CREB3 CREB3L4 CREBBP CREM CRP CTNNB1 DHH ELK1 GLI1 GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAT1 GNAT2 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GRK1 GRK7 GSK3A GSK3B GYS1 GYS2 H1-0 H1-1 H1-10 H1-2 H1-3 H1-4 H1-5 H1-6 H3-3A H3-3B H3-4 H3C1 H3C10 H3C11 H3C12 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 IHH ITPR1 ITPR2 ITPR3 KCMF1 KCNK1 KCNK10 KCNK12 KCNK13 KCNK15 KCNK16 KCNK17 KCNK2 KCNK3 KCNK4 KCNK5 KCNK6 KCNK7 KCNK9 KCNRG KCNT1 KCNT2 KCNU1 KCNV1 KCNV2 KCTD1 KCTD10 KCTD11 KCTD12 KCTD13 KCTD14 KCTD15 KCTD2 KCTD3 KCTD4 KCTD5 KCTD6 KCTD7 KCTD8 KCTD9 KDELR1 KDELR2 KDELR3 LEFTY2 LIPE MAP2K1 MAP2K2 MAPK1 MAPK3 MYL1 MYL11 MYL2 MYL3 MYL4 MYL5 MYL6 MYL7 MYL9 MYLK NFAT5 NFATC1 NFATC2 NFATC3 NFATC4 NFKB1 NFKBIA NFKBIB NFKBIE NGFR NOS3 NTN1 PDE1A PDE1B PDE1C PDE2A PDE3A PDE3B PHKA1 PHKA2 PHKB PHKG1 PHKG2 PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PLN PPP1R10 PPP1R11 PPP1R12A PPP1R12B PPP1R12C PPP1R13B PPP1R14A PPP1R14B PPP1R15A PPP1R16A PPP1R1A PPP1R1B PPP1R2 PPP1R3A PPP1R3B PPP1R3C PPP1R3D PPP1R3F PPP1R7 PPP1R8 PPP1R9A PPP1R9B PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCQ PRKD1 PRKD3 PTCH1 PTCH2 PTK2 PTK2B PTPN1 PTPN2 PTPN3 PTPRA PTPRB PTPRC PXN PYGB PYGL PYGM RAF1 RAP1A RAP1B RHOA ROCK1 ROCK2 RYR1 RYR2 RYR3 SCN10A SCN11A SCN1A SCN1B SCN2A SCN2B SCN3A SCN3B SCN4A SCN4B SCN5A SCN7A SCN8A SCN9A SCNN1A SCNN1B SCNN1D SCNN1G SMAD3 SMAD4 SMO TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TH TNNI1 TNNI2 TNNI3 TP53BP2 VASP YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 349) (see less)

Gene overlap in member pathways for Activation of cAMP-Dependent PKA SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ADCY1	Adenylate Cyclase 1	Protein Coding	4
2	ADCY2	Adenylate Cyclase 2	Protein Coding	4
3	ADCY3	Adenylate Cyclase 3	Protein Coding	4
4	ADCY4	Adenylate Cyclase 4	Protein Coding	4
5	ADCY5	Adenylate Cyclase 5	Protein Coding	4
6	ADCY6	Adenylate Cyclase 6	Protein Coding	4
7	ADCY7	Adenylate Cyclase 7	Protein Coding	4
8	ADCY8	Adenylate Cyclase 8	Protein Coding	4
9	ADCY9	Adenylate Cyclase 9	Protein Coding	4
10	ADD1	Adducin 1	Protein Coding	4
11	ADD2	Adducin 2	Protein Coding	4
12	ADD3	Adducin 3	Protein Coding	4
13	AKAP1	A-Kinase Anchoring Protein 1	Protein Coding	4
14	AKAP10	A-Kinase Anchoring Protein 10	Protein Coding	4
15	AKAP11	A-Kinase Anchoring Protein 11	Protein Coding	4
16	AKAP12	A-Kinase Anchoring Protein 12	Protein Coding	4
17	AKAP13	A-Kinase Anchoring Protein 13	Protein Coding	4
18	AKAP3	A-Kinase Anchoring Protein 3	Protein Coding	4
19	AKAP4	A-Kinase Anchoring Protein 4	Protein Coding	4
20	AKAP5	A-Kinase Anchoring Protein 5	Protein Coding	4
21	AKAP6	A-Kinase Anchoring Protein 6	Protein Coding	4
22	AKAP7	A-Kinase Anchoring Protein 7	Protein Coding	4
23	AKAP8	A-Kinase Anchoring Protein 8	Protein Coding	4
24	AKAP9	A-Kinase Anchoring Protein 9	Protein Coding	4
25	RHOA	Ras Homolog Family Member A	Protein Coding	4
26	ATF1	Activating Transcription Factor 1	Protein Coding	4
27	ATF4	Activating Transcription Factor 4	Protein Coding	4
28	BAD	BCL2 Associated Agonist Of Cell Death	Protein Coding	4
29	BRAF	B-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	4
30	CREB1	CAMP Responsive Element Binding Protein 1	Protein Coding	4
31	CREB3	CAMP Responsive Element Binding Protein 3	Protein Coding	4
32	CREB3L4	CAMP Responsive Element Binding Protein 3 Like 4	Protein Coding	4
33	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	4
34	CREM	CAMP Responsive Element Modulator	Protein Coding	4
35	CRP	C-Reactive Protein	Protein Coding	4
36	LEFTY2	Left-Right Determination Factor 2	Protein Coding	4
37	ELK1	ETS Transcription Factor ELK1	Protein Coding	4
38	GNA11	G Protein Subunit Alpha 11	Protein Coding	4
39	GNA12	G Protein Subunit Alpha 12	Protein Coding	4
40	GNA13	G Protein Subunit Alpha 13	Protein Coding	4
41	GNA14	G Protein Subunit Alpha 14	Protein Coding	4
42	GNA15	G Protein Subunit Alpha 15	Protein Coding	4
43	GNAI1	G Protein Subunit Alpha I1	Protein Coding	4
44	GNAI2	G Protein Subunit Alpha I2	Protein Coding	4
45	GNAI3	G Protein Subunit Alpha I3	Protein Coding	4
46	GNAL	G Protein Subunit Alpha L	Protein Coding	4
47	GNAO1	G Protein Subunit Alpha O1	Protein Coding	4
48	GNAS	GNAS Complex Locus	Protein Coding	4
49	GNAZ	G Protein Subunit Alpha Z	Protein Coding	4
50	GNB1	G Protein Subunit Beta 1	Protein Coding	4
51	GNB2	G Protein Subunit Beta 2	Protein Coding	4
52	GNB3	G Protein Subunit Beta 3	Protein Coding	4
53	GNB4	G Protein Subunit Beta 4	Protein Coding	4
54	GNB5	G Protein Subunit Beta 5	Protein Coding	4
55	GNG10	G Protein Subunit Gamma 10	Protein Coding	4
56	GNG11	G Protein Subunit Gamma 11	Protein Coding	4
57	GNG12	G Protein Subunit Gamma 12	Protein Coding	4
58	GNG13	G Protein Subunit Gamma 13	Protein Coding	4
59	GNG2	G Protein Subunit Gamma 2	Protein Coding	4
60	GNG3	G Protein Subunit Gamma 3	Protein Coding	4
61	GNG4	G Protein Subunit Gamma 4	Protein Coding	4
62	GNG5	G Protein Subunit Gamma 5	Protein Coding	4
63	GNG7	G Protein Subunit Gamma 7	Protein Coding	4
64	GNG8	G Protein Subunit Gamma 8	Protein Coding	4
65	GNGT1	G Protein Subunit Gamma Transducin 1	Protein Coding	4
66	GNGT2	G Protein Subunit Gamma Transducin 2	Protein Coding	4
67	GSK3A	Glycogen Synthase Kinase 3 Alpha	Protein Coding	4
68	GSK3B	Glycogen Synthase Kinase 3 Beta	Protein Coding	4
69	GYS1	Glycogen Synthase 1	Protein Coding	4
70	GYS2	Glycogen Synthase 2	Protein Coding	4
71	MYL11	Myosin Light Chain 11	Protein Coding	4
72	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	4
73	ITPR2	Inositol 1,4,5-Trisphosphate Receptor Type 2	Protein Coding	4
74	ITPR3	Inositol 1,4,5-Trisphosphate Receptor Type 3	Protein Coding	4
75	KDELR1	KDEL Endoplasmic Reticulum Protein Retention Receptor 1	Protein Coding	4
76	KDELR2	KDEL Endoplasmic Reticulum Protein Retention Receptor 2	Protein Coding	4
77	KDELR3	KDEL Endoplasmic Reticulum Protein Retention Receptor 3	Protein Coding	4
78	LIPE	Lipase E, Hormone Sensitive Type	Protein Coding	4
79	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	4
80	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	4
81	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	4
82	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	4
83	CLEC18C	C-Type Lectin Domain Family 18 Member C	Protein Coding	4
84	MYL1	Myosin Light Chain 1	Protein Coding	4
85	MYL2	Myosin Light Chain 2	Protein Coding	4
86	MYL3	Myosin Light Chain 3	Protein Coding	4
87	MYL4	Myosin Light Chain 4	Protein Coding	4
88	MYL5	Myosin Light Chain 5	Protein Coding	4
89	MYL6	Myosin Light Chain 6	Protein Coding	4
90	MYL7	Myosin Light Chain 7	Protein Coding	4
91	MYL9	Myosin Light Chain 9	Protein Coding	4
92	NFAT5	Nuclear Factor Of Activated T Cells 5	Protein Coding	4
93	NFATC1	Nuclear Factor Of Activated T Cells 1	Protein Coding	4
94	NFATC2	Nuclear Factor Of Activated T Cells 2	Protein Coding	4
95	NFATC3	Nuclear Factor Of Activated T Cells 3	Protein Coding	4
96	NFATC4	Nuclear Factor Of Activated T Cells 4	Protein Coding	4
97	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	4
98	NOS3	Nitric Oxide Synthase 3	Protein Coding	4
99	PDE1A	Phosphodiesterase 1A	Protein Coding	4
100	PDE1B	Phosphodiesterase 1B	Protein Coding	4
101	PDE1C	Phosphodiesterase 1C	Protein Coding	4
102	PDE2A	Phosphodiesterase 2A	Protein Coding	4
103	PDE3A	Phosphodiesterase 3A	Protein Coding	4
104	PDE3B	Phosphodiesterase 3B	Protein Coding	4
105	PLCB1	Phospholipase C Beta 1	Protein Coding	4
106	PLCB2	Phospholipase C Beta 2	Protein Coding	4
107	PLCB3	Phospholipase C Beta 3	Protein Coding	4
108	PLCB4	Phospholipase C Beta 4	Protein Coding	4
109	PLCD1	Phospholipase C Delta 1	Protein Coding	4
110	PLCD3	Phospholipase C Delta 3	Protein Coding	4
111	PLCD4	Phospholipase C Delta 4	Protein Coding	4
112	PLCE1	Phospholipase C Epsilon 1	Protein Coding	4
113	PLCG1	Phospholipase C Gamma 1	Protein Coding	4
114	PLCG2	Phospholipase C Gamma 2	Protein Coding	4
115	PLCZ1	Phospholipase C Zeta 1	Protein Coding	4
116	PLN	Phospholamban	Protein Coding	4
117	PPP1R10	Protein Phosphatase 1 Regulatory Subunit 10	Protein Coding	4
118	PPP1R11	Protein Phosphatase 1 Regulatory Inhibitor Subunit 11	Protein Coding	4
119	PPP1R12A	Protein Phosphatase 1 Regulatory Subunit 12A	Protein Coding	4
120	PPP1R12B	Protein Phosphatase 1 Regulatory Subunit 12B	Protein Coding	4
121	PPP1R12C	Protein Phosphatase 1 Regulatory Subunit 12C	Protein Coding	4
122	PPP1R13B	Protein Phosphatase 1 Regulatory Subunit 13B	Protein Coding	4
123	PPP1R14A	Protein Phosphatase 1 Regulatory Inhibitor Subunit 14A	Protein Coding	4
124	PPP1R14B	Protein Phosphatase 1 Regulatory Inhibitor Subunit 14B	Protein Coding	4
125	PPP1R15A	Protein Phosphatase 1 Regulatory Subunit 15A	Protein Coding	4
126	PPP1R16A	Protein Phosphatase 1 Regulatory Subunit 16A	Protein Coding	4
127	PPP1R1A	Protein Phosphatase 1 Regulatory Inhibitor Subunit 1A	Protein Coding	4
128	PPP1R1B	Protein Phosphatase 1 Regulatory Inhibitor Subunit 1B	Protein Coding	4
129	PPP1R2	Protein Phosphatase 1 Regulatory Inhibitor Subunit 2	Protein Coding	4
130	PPP1R3A	Protein Phosphatase 1 Regulatory Subunit 3A	Protein Coding	4
131	PPP1R3B	Protein Phosphatase 1 Regulatory Subunit 3B	Protein Coding	4
132	PPP1R3C	Protein Phosphatase 1 Regulatory Subunit 3C	Protein Coding	4
133	PPP1R3D	Protein Phosphatase 1 Regulatory Subunit 3D	Protein Coding	4
134	PPP1R3F	Protein Phosphatase 1 Regulatory Subunit 3F	Protein Coding	4
135	PPP1R7	Protein Phosphatase 1 Regulatory Subunit 7	Protein Coding	4
136	PPP1R8	Protein Phosphatase 1 Regulatory Subunit 8	Protein Coding	4
137	PPP1R9A	Protein Phosphatase 1 Regulatory Subunit 9A	Protein Coding	4
138	PPP1R9B	Protein Phosphatase 1 Regulatory Subunit 9B	Protein Coding	4
139	PPP3CA	Protein Phosphatase 3 Catalytic Subunit Alpha	Protein Coding	4
140	PPP3CB	Protein Phosphatase 3 Catalytic Subunit Beta	Protein Coding	4
141	PPP3CC	Protein Phosphatase 3 Catalytic Subunit Gamma	Protein Coding	4
142	PPP3R1	Protein Phosphatase 3 Regulatory Subunit B, Alpha	Protein Coding	4
143	PPP3R2	Protein Phosphatase 3 Regulatory Subunit B, Beta	Protein Coding	4
144	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	4
145	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	4
146	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	4
147	PRKAR1A	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha	Protein Coding	4
148	PRKAR1B	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Beta	Protein Coding	4
149	PRKAR2A	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Alpha	Protein Coding	4
150	PRKAR2B	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Beta	Protein Coding	4
151	PRKCA	Protein Kinase C Alpha	Protein Coding	4
152	PRKCB	Protein Kinase C Beta	Protein Coding	4
153	PRKCD	Protein Kinase C Delta	Protein Coding	4
154	PRKCE	Protein Kinase C Epsilon	Protein Coding	4
155	PRKCG	Protein Kinase C Gamma	Protein Coding	4
156	PRKCH	Protein Kinase C Eta	Protein Coding	4
157	PRKD1	Protein Kinase D1	Protein Coding	4
158	PRKD3	Protein Kinase D3	Protein Coding	4
159	PRKCQ	Protein Kinase C Theta	Protein Coding	4
160	PTPN1	Protein Tyrosine Phosphatase Non-Receptor Type 1	Protein Coding	4
161	PTPN2	Protein Tyrosine Phosphatase Non-Receptor Type 2	Protein Coding	4
162	PTPN3	Protein Tyrosine Phosphatase Non-Receptor Type 3	Protein Coding	4
163	PTPRA	Protein Tyrosine Phosphatase Receptor Type A	Protein Coding	4
164	PTPRB	Protein Tyrosine Phosphatase Receptor Type B	Protein Coding	4
165	PTPRC	Protein Tyrosine Phosphatase Receptor Type C	Protein Coding	4
166	PYGB	Glycogen Phosphorylase B	Protein Coding	4
167	PYGL	Glycogen Phosphorylase L	Protein Coding	4
168	PYGM	Glycogen Phosphorylase, Muscle Associated	Protein Coding	4
169	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	4
170	RAP1A	RAP1A, Member Of RAS Oncogene Family	Protein Coding	4
171	ROCK1	Rho Associated Coiled-Coil Containing Protein Kinase 1	Protein Coding	4
172	ROCK2	Rho Associated Coiled-Coil Containing Protein Kinase 2	Protein Coding	4
173	RYR1	Ryanodine Receptor 1	Protein Coding	4
174	RYR2	Ryanodine Receptor 2	Protein Coding	4
175	RYR3	Ryanodine Receptor 3	Protein Coding	4
176	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	4
177	TGFB2	Transforming Growth Factor Beta 2	Protein Coding	4
178	TGFB3	Transforming Growth Factor Beta 3	Protein Coding	4
179	TNNI1	Troponin I1, Slow Skeletal Type	Protein Coding	4
180	TNNI2	Troponin I2, Fast Skeletal Type	Protein Coding	4
181	TNNI3	Troponin I3, Cardiac Type	Protein Coding	4
182	TP53BP2	Tumor Protein P53 Binding Protein 2	Protein Coding	4
183	YWHAB	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Beta	Protein Coding	4
184	YWHAE	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon	Protein Coding	4
185	YWHAG	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Gamma	Protein Coding	4
186	YWHAH	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Eta	Protein Coding	4
187	YWHAQ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Theta	Protein Coding	4
188	YWHAZ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta	Protein Coding	4
189	ADRA1A	Adrenoceptor Alpha 1A	Protein Coding	3
190	ADRA1B	Adrenoceptor Alpha 1B	Protein Coding	3
191	ADRA1D	Adrenoceptor Alpha 1D	Protein Coding	3
192	ADRA2A	Adrenoceptor Alpha 2A	Protein Coding	3
193	ADRA2B	Adrenoceptor Alpha 2B	Protein Coding	3
194	ADRA2C	Adrenoceptor Alpha 2C	Protein Coding	3
195	ADRB1	Adrenoceptor Beta 1	Protein Coding	3
196	ADRB2	Adrenoceptor Beta 2	Protein Coding	3
197	ADRB3	Adrenoceptor Beta 3	Protein Coding	3
198	ANGPTL6	Angiopoietin Like 6	Protein Coding	3
199	AREG	Amphiregulin	Protein Coding	3
200	BDNF	Brain Derived Neurotrophic Factor	Protein Coding	3
201	BMP1	Bone Morphogenetic Protein 1	Protein Coding	3
202	BMP10	Bone Morphogenetic Protein 10	Protein Coding	3
203	BMP2	Bone Morphogenetic Protein 2	Protein Coding	3
204	BMP3	Bone Morphogenetic Protein 3	Protein Coding	3
205	BMP4	Bone Morphogenetic Protein 4	Protein Coding	3
206	BMP5	Bone Morphogenetic Protein 5	Protein Coding	3
207	BMP6	Bone Morphogenetic Protein 6	Protein Coding	3
208	BMP7	Bone Morphogenetic Protein 7	Protein Coding	3
209	BMP8A	Bone Morphogenetic Protein 8a	Protein Coding	3
210	BTC	Betacellulin	Protein Coding	3
211	CACNA1A	Calcium Voltage-Gated Channel Subunit Alpha1 A	Protein Coding	3
212	CACNA1B	Calcium Voltage-Gated Channel Subunit Alpha1 B	Protein Coding	3
213	CACNA1C	Calcium Voltage-Gated Channel Subunit Alpha1 C	Protein Coding	3
214	CACNA1D	Calcium Voltage-Gated Channel Subunit Alpha1 D	Protein Coding	3
215	CACNA1E	Calcium Voltage-Gated Channel Subunit Alpha1 E	Protein Coding	3
216	CACNA1F	Calcium Voltage-Gated Channel Subunit Alpha1 F	Protein Coding	3
217	CACNA1G	Calcium Voltage-Gated Channel Subunit Alpha1 G	Protein Coding	3
218	CACNA1H	Calcium Voltage-Gated Channel Subunit Alpha1 H	Protein Coding	3
219	CACNA1I	Calcium Voltage-Gated Channel Subunit Alpha1 I	Protein Coding	3
220	CACNA1S	Calcium Voltage-Gated Channel Subunit Alpha1 S	Protein Coding	3
221	CACNA2D1	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 1	Protein Coding	3
222	CACNA2D2	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 2	Protein Coding	3
223	CACNA2D3	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 3	Protein Coding	3
224	CACNA2D4	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 4	Protein Coding	3
225	CACNB1	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 1	Protein Coding	3
226	CACNB2	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 2	Protein Coding	3
227	CACNB3	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 3	Protein Coding	3
228	CACNB4	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 4	Protein Coding	3
229	CACNG1	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 1	Protein Coding	3
230	CACNG2	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 2	Protein Coding	3
231	CACNG3	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 3	Protein Coding	3
232	CACNG4	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 4	Protein Coding	3
233	CACNG5	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 5	Protein Coding	3
234	CACNG6	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 6	Protein Coding	3
235	CACNG7	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 7	Protein Coding	3
236	CACNG8	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 8	Protein Coding	3
237	CALM1	Calmodulin 1	Protein Coding	3
238	CALM2	Calmodulin 2	Protein Coding	3
239	CALM3	Calmodulin 3	Protein Coding	3
240	CAMK4	Calcium/Calmodulin Dependent Protein Kinase IV	Protein Coding	3
241	CLCA1	Chloride Channel Accessory 1	Protein Coding	3
242	CLCA2	Chloride Channel Accessory 2	Protein Coding	3
243	CLCA3P	Chloride Channel Accessory 3, Pseudogene	Pseudogene	3
244	CLCA4	Chloride Channel Accessory 4	Protein Coding	3
245	CLCN1	Chloride Voltage-Gated Channel 1	Protein Coding	3
246	CLCN2	Chloride Voltage-Gated Channel 2	Protein Coding	3
247	CLCN3	Chloride Voltage-Gated Channel 3	Protein Coding	3
248	CLCN4	Chloride Voltage-Gated Channel 4	Protein Coding	3
249	CLCN5	Chloride Voltage-Gated Channel 5	Protein Coding	3
250	CLCN6	Chloride Voltage-Gated Channel 6	Protein Coding	3
251	CLCN7	Chloride Voltage-Gated Channel 7	Protein Coding	3
252	CLIC1	Chloride Intracellular Channel 1	Protein Coding	3
253	CLIC2	Chloride Intracellular Channel 2	Protein Coding	3
254	CLIC3	Chloride Intracellular Channel 3	Protein Coding	3
255	CLIC4	Chloride Intracellular Channel 4	Protein Coding	3
256	CLIC5	Chloride Intracellular Channel 5	Protein Coding	3
257	CLIC6	Chloride Intracellular Channel 6	Protein Coding	3
258	CLNS1A	Chloride Nucleotide-Sensitive Channel 1A	Protein Coding	3
259	CNGA1	Cyclic Nucleotide Gated Channel Subunit Alpha 1	Protein Coding	3
260	CNGA3	Cyclic Nucleotide Gated Channel Subunit Alpha 3	Protein Coding	3
261	CNGA4	Cyclic Nucleotide Gated Channel Subunit Alpha 4	Protein Coding	3
262	CNGB1	Cyclic Nucleotide Gated Channel Subunit Beta 1	Protein Coding	3
263	CNGB3	Cyclic Nucleotide Gated Channel Subunit Beta 3	Protein Coding	3
264	CCN2	Cellular Communication Network Factor 2	Protein Coding	3
265	CXCL12	C-X-C Motif Chemokine Ligand 12	Protein Coding	3
266	TYMP	Thymidine Phosphorylase	Protein Coding	3
267	EGFR	Epidermal Growth Factor Receptor	Protein Coding	3
268	FGF1	Fibroblast Growth Factor 1	Protein Coding	3
269	FGF10	Fibroblast Growth Factor 10	Protein Coding	3
270	FGF11	Fibroblast Growth Factor 11	Protein Coding	3
271	FGF12	Fibroblast Growth Factor 12	Protein Coding	3
272	FGF13	Fibroblast Growth Factor 13	Protein Coding	3
273	FGF14	Fibroblast Growth Factor 14	Protein Coding	3
274	FGF16	Fibroblast Growth Factor 16	Protein Coding	3
275	FGF17	Fibroblast Growth Factor 17	Protein Coding	3
276	FGF18	Fibroblast Growth Factor 18	Protein Coding	3
277	FGF19	Fibroblast Growth Factor 19	Protein Coding	3
278	FGF2	Fibroblast Growth Factor 2	Protein Coding	3
279	FGF20	Fibroblast Growth Factor 20	Protein Coding	3
280	FGF21	Fibroblast Growth Factor 21	Protein Coding	3
281	FGF22	Fibroblast Growth Factor 22	Protein Coding	3
282	FGF23	Fibroblast Growth Factor 23	Protein Coding	3
283	FGF4	Fibroblast Growth Factor 4	Protein Coding	3
284	FGF5	Fibroblast Growth Factor 5	Protein Coding	3
285	FGF6	Fibroblast Growth Factor 6	Protein Coding	3
286	FGF7	Fibroblast Growth Factor 7	Protein Coding	3
287	FGF8	Fibroblast Growth Factor 8	Protein Coding	3
288	FGFR1	Fibroblast Growth Factor Receptor 1	Protein Coding	3
289	FGFR2	Fibroblast Growth Factor Receptor 2	Protein Coding	3
290	FGFR3	Fibroblast Growth Factor Receptor 3	Protein Coding	3
291	FGFR4	Fibroblast Growth Factor Receptor 4	Protein Coding	3
292	VEGFD	Vascular Endothelial Growth Factor D	Protein Coding	3
293	FLT1	Fms Related Receptor Tyrosine Kinase 1	Protein Coding	3
294	FLT4	Fms Related Receptor Tyrosine Kinase 4	Protein Coding	3
295	GAS1	Growth Arrest Specific 1	Protein Coding	3
296	GAS2	Growth Arrest Specific 2	Protein Coding	3
297	GAS6	Growth Arrest Specific 6	Protein Coding	3
298	DRC4	Dynein Regulatory Complex Subunit 4	Protein Coding	3
299	GCG	Glucagon	Protein Coding	3
300	GCGR	Glucagon Receptor	Protein Coding	3
301	GDF10	Growth Differentiation Factor 10	Protein Coding	3
302	GDF2	Growth Differentiation Factor 2	Protein Coding	3
303	GDF5	Growth Differentiation Factor 5	Protein Coding	3
304	GDF6	Growth Differentiation Factor 6	Protein Coding	3
305	GDF9	Growth Differentiation Factor 9	Protein Coding	3
306	GFER	Growth Factor, Augmenter Of Liver Regeneration	Protein Coding	3
307	GH1	Growth Hormone 1	Protein Coding	3
308	GH2	Growth Hormone 2	Protein Coding	3
309	GHRH	Growth Hormone Releasing Hormone	Protein Coding	3
310	GMFG	Glia Maturation Factor Gamma	Protein Coding	3
311	GNRH1	Gonadotropin Releasing Hormone 1	Protein Coding	3
312	GNRH2	Gonadotropin Releasing Hormone 2	Protein Coding	3
313	GPC6	Glypican 6	Protein Coding	3
314	GRK7	G Protein-Coupled Receptor Kinase 7	Protein Coding	3
315	HDGF	Heparin Binding Growth Factor	Protein Coding	3
316	HGF	Hepatocyte Growth Factor	Protein Coding	3
317	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	3
318	IGF1	Insulin Like Growth Factor 1	Protein Coding	3
319	IGF1R	Insulin Like Growth Factor 1 Receptor	Protein Coding	3
320	IGF2	Insulin Like Growth Factor 2	Protein Coding	3
321	IL2	Interleukin 2	Protein Coding	3
322	IL3	Interleukin 3	Protein Coding	3
323	IL6	Interleukin 6	Protein Coding	3
324	IL9	Interleukin 9	Protein Coding	3
325	KCMF1	Potassium Channel Modulatory Factor 1	Protein Coding	3
326	KCNK1	Potassium Two Pore Domain Channel Subfamily K Member 1	Protein Coding	3
327	KCNK10	Potassium Two Pore Domain Channel Subfamily K Member 10	Protein Coding	3
328	KCNK12	Potassium Two Pore Domain Channel Subfamily K Member 12	Protein Coding	3
329	KCNK13	Potassium Two Pore Domain Channel Subfamily K Member 13	Protein Coding	3
330	KCNK15	Potassium Two Pore Domain Channel Subfamily K Member 15	Protein Coding	3
331	KCNK16	Potassium Two Pore Domain Channel Subfamily K Member 16	Protein Coding	3
332	KCNK17	Potassium Two Pore Domain Channel Subfamily K Member 17	Protein Coding	3
333	KCNK2	Potassium Two Pore Domain Channel Subfamily K Member 2	Protein Coding	3
334	KCNK3	Potassium Two Pore Domain Channel Subfamily K Member 3	Protein Coding	3
335	KCNK4	Potassium Two Pore Domain Channel Subfamily K Member 4	Protein Coding	3
336	KCNK5	Potassium Two Pore Domain Channel Subfamily K Member 5	Protein Coding	3
337	KCNK6	Potassium Two Pore Domain Channel Subfamily K Member 6	Protein Coding	3
338	KCNK7	Potassium Two Pore Domain Channel Subfamily K Member 7	Protein Coding	3
339	KCNK9	Potassium Two Pore Domain Channel Subfamily K Member 9	Protein Coding	3
340	KCNRG	Potassium Channel Regulator	Protein Coding	3
341	KCNT1	Potassium Sodium-Activated Channel Subfamily T Member 1	Protein Coding	3
342	KCNU1	Potassium Calcium-Activated Channel Subfamily U Member 1	Protein Coding	3
343	KCNV1	Potassium Voltage-Gated Channel Modifier Subfamily V Member 1	Protein Coding	3
344	KCNV2	Potassium Voltage-Gated Channel Modifier Subfamily V Member 2	Protein Coding	3
345	KCTD1	Potassium Channel Tetramerization Domain Containing 1	Protein Coding	3
346	KCTD10	Potassium Channel Tetramerization Domain Containing 10	Protein Coding	3
347	KCTD11	Potassium Channel Tetramerization Domain Containing 11	Protein Coding	3
348	KCTD12	Potassium Channel Tetramerization Domain Containing 12	Protein Coding	3
349	KCTD13	Potassium Channel Tetramerization Domain Containing 13	Protein Coding	3
350	KCTD14	Potassium Channel Tetramerization Domain Containing 14	Protein Coding	3
351	KCTD15	Potassium Channel Tetramerization Domain Containing 15	Protein Coding	3
352	KCTD2	Potassium Channel Tetramerization Domain Containing 2	Protein Coding	3
353	KCTD3	Potassium Channel Tetramerization Domain Containing 3	Protein Coding	3
354	KCTD4	Potassium Channel Tetramerization Domain Containing 4	Protein Coding	3
355	KCTD5	Potassium Channel Tetramerization Domain Containing 5	Protein Coding	3
356	KCTD6	Potassium Channel Tetramerization Domain Containing 6	Protein Coding	3
357	KCTD7	Potassium Channel Tetramerization Domain Containing 7	Protein Coding	3
358	KCTD8	Potassium Channel Tetramerization Domain Containing 8	Protein Coding	3
359	KCTD9	Potassium Channel Tetramerization Domain Containing 9	Protein Coding	3
360	KDR	Kinase Insert Domain Receptor	Protein Coding	3
361	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	3
362	KITLG	KIT Ligand	Protein Coding	3
363	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	3
364	LEFTY1	Left-Right Determination Factor 1	Protein Coding	3
365	LHB	Luteinizing Hormone Subunit Beta	Protein Coding	3
366	LTBP1	Latent Transforming Growth Factor Beta Binding Protein 1	Protein Coding	3
367	LTBP2	Latent Transforming Growth Factor Beta Binding Protein 2	Protein Coding	3
368	LTBP3	Latent Transforming Growth Factor Beta Binding Protein 3	Protein Coding	3
369	LTBP4	Latent Transforming Growth Factor Beta Binding Protein 4	Protein Coding	3
370	MDK	Midkine	Protein Coding	3
371	MET	MET Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	3
372	MRAS	Muscle RAS Oncogene Homolog	Protein Coding	3
373	NGF	Nerve Growth Factor	Protein Coding	3
374	NRAS	NRAS Proto-Oncogene, GTPase	Protein Coding	3
375	NRG1	Neuregulin 1	Protein Coding	3
376	NRG2	Neuregulin 2	Protein Coding	3
377	NRG3	Neuregulin 3	Protein Coding	3
378	NTF3	Neurotrophin 3	Protein Coding	3
379	NTF4	Neurotrophin 4	Protein Coding	3
380	NTN1	Netrin 1	Protein Coding	3
381	NTRK1	Neurotrophic Receptor Tyrosine Kinase 1	Protein Coding	3
382	NTRK2	Neurotrophic Receptor Tyrosine Kinase 2	Protein Coding	3
383	NTRK3	Neurotrophic Receptor Tyrosine Kinase 3	Protein Coding	3
384	NUDT6	Nudix Hydrolase 6	Protein Coding	3
385	OGN	Osteoglycin	Protein Coding	3
386	PDGFA	Platelet Derived Growth Factor Subunit A	Protein Coding	3
387	PDGFB	Platelet Derived Growth Factor Subunit B	Protein Coding	3
388	PDGFC	Platelet Derived Growth Factor C	Protein Coding	3
389	PDGFRA	Platelet Derived Growth Factor Receptor Alpha	Protein Coding	3
390	PDGFRB	Platelet Derived Growth Factor Receptor Beta	Protein Coding	3
391	PENK	Proenkephalin	Protein Coding	3
392	PGF	Placental Growth Factor	Protein Coding	3
393	PHKA1	Phosphorylase Kinase Regulatory Subunit Alpha 1	Protein Coding	3
394	PHKA2	Phosphorylase Kinase Regulatory Subunit Alpha 2	Protein Coding	3
395	PHKB	Phosphorylase Kinase Regulatory Subunit Beta	Protein Coding	3
396	PHKG1	Phosphorylase Kinase Catalytic Subunit Gamma 1	Protein Coding	3
397	PHKG2	Phosphorylase Kinase Catalytic Subunit Gamma 2	Protein Coding	3
398	GDF15	Growth Differentiation Factor 15	Protein Coding	3
399	PLPP3	Phospholipid Phosphatase 3	Protein Coding	3
400	PPBP	Pro-Platelet Basic Protein	Protein Coding	3
401	PROK1	Prokineticin 1	Protein Coding	3
402	PSIP1	PC4 And SRSF1 Interacting Protein 1	Protein Coding	3
403	PTN	Pleiotrophin	Protein Coding	3
404	RAP1B	RAP1B, Member Of RAS Oncogene Family	Protein Coding	3
405	GRK1	G Protein-Coupled Receptor Kinase 1	Protein Coding	3
406	RRAS	RAS Related	Protein Coding	3
407	RRAS2	RAS Related 2	Protein Coding	3
408	PDGFD	Platelet Derived Growth Factor D	Protein Coding	3
409	CLEC11A	C-Type Lectin Domain Containing 11A	Protein Coding	3
410	SCN10A	Sodium Voltage-Gated Channel Alpha Subunit 10	Protein Coding	3
411	SCN11A	Sodium Voltage-Gated Channel Alpha Subunit 11	Protein Coding	3
412	SCN1A	Sodium Voltage-Gated Channel Alpha Subunit 1	Protein Coding	3
413	SCN1B	Sodium Voltage-Gated Channel Beta Subunit 1	Protein Coding	3
414	SCN2A	Sodium Voltage-Gated Channel Alpha Subunit 2	Protein Coding	3
415	SCN2B	Sodium Voltage-Gated Channel Beta Subunit 2	Protein Coding	3
416	SCN3A	Sodium Voltage-Gated Channel Alpha Subunit 3	Protein Coding	3
417	SCN3B	Sodium Voltage-Gated Channel Beta Subunit 3	Protein Coding	3
418	SCN4A	Sodium Voltage-Gated Channel Alpha Subunit 4	Protein Coding	3
419	SCN4B	Sodium Voltage-Gated Channel Beta Subunit 4	Protein Coding	3
420	SCN5A	Sodium Voltage-Gated Channel Alpha Subunit 5	Protein Coding	3
421	SCN7A	Sodium Voltage-Gated Channel Alpha Subunit 7	Protein Coding	3
422	SCN8A	Sodium Voltage-Gated Channel Alpha Subunit 8	Protein Coding	3
423	SCN9A	Sodium Voltage-Gated Channel Alpha Subunit 9	Protein Coding	3
424	SCNN1A	Sodium Channel Epithelial 1 Subunit Alpha	Protein Coding	3
425	SCNN1B	Sodium Channel Epithelial 1 Subunit Beta	Protein Coding	3
426	SCNN1D	Sodium Channel Epithelial 1 Subunit Delta	Protein Coding	3
427	SCNN1G	Sodium Channel Epithelial 1 Subunit Gamma	Protein Coding	3
428	SEMA3A	Semaphorin 3A	Protein Coding	3
429	SEMA4B	Semaphorin 4B	Protein Coding	3
430	SEMA4G	Semaphorin 4G	Protein Coding	3
431	SEMA5A	Semaphorin 5A	Protein Coding	3
432	KCNT2	Potassium Sodium-Activated Channel Subfamily T Member 2	Protein Coding	3
433	SPON1	Spondin 1	Protein Coding	3
434	TBRG1	Transforming Growth Factor Beta Regulator 1	Protein Coding	3
435	CRIPTO	Cripto, EGF-CFC Family Member	Protein Coding	3
436	TGFA	Transforming Growth Factor Alpha	Protein Coding	3
437	THPO	Thrombopoietin	Protein Coding	3
438	KLF10	KLF Transcription Factor 10	Protein Coding	3
439	TIMP1	TIMP Metallopeptidase Inhibitor 1	Protein Coding	3
440	TIMP2	TIMP Metallopeptidase Inhibitor 2	Protein Coding	3
441	TIMP3	TIMP Metallopeptidase Inhibitor 3	Protein Coding	3
442	TIMP4	TIMP Metallopeptidase Inhibitor 4	Protein Coding	3
443	UCN	Urocortin	Protein Coding	3
444	UTS2	Urotensin 2	Protein Coding	3
445	VASP	Vasodilator Stimulated Phosphoprotein	Protein Coding	3
446	VEGFB	Vascular Endothelial Growth Factor B	Protein Coding	3
447	VEGFC	Vascular Endothelial Growth Factor C	Protein Coding	3
448	GNAT1	G Protein Subunit Alpha Transducin 1	Protein Coding	3
449	GNAT2	G Protein Subunit Alpha Transducin 2	Protein Coding	3
450	ALK	ALK Receptor Tyrosine Kinase	Protein Coding	2
451	AXL	AXL Receptor Tyrosine Kinase	Protein Coding	2
452	CAMK1	Calcium/Calmodulin Dependent Protein Kinase I	Protein Coding	2
453	CAMK1G	Calcium/Calmodulin Dependent Protein Kinase IG	Protein Coding	2
454	CAMK2A	Calcium/Calmodulin Dependent Protein Kinase II Alpha	Protein Coding	2
455	CAMK2B	Calcium/Calmodulin Dependent Protein Kinase II Beta	Protein Coding	2
456	CAMK2D	Calcium/Calmodulin Dependent Protein Kinase II Delta	Protein Coding	2
457	CAMK2G	Calcium/Calmodulin Dependent Protein Kinase II Gamma	Protein Coding	2
458	CRHR1	Corticotropin Releasing Hormone Receptor 1	Protein Coding	2
459	CRHR2	Corticotropin Releasing Hormone Receptor 2	Protein Coding	2
460	CSF1R	Colony Stimulating Factor 1 Receptor	Protein Coding	2
461	DDR1	Discoidin Domain Receptor Tyrosine Kinase 1	Protein Coding	2
462	DDR2	Discoidin Domain Receptor Tyrosine Kinase 2	Protein Coding	2
463	EGF	Epidermal Growth Factor	Protein Coding	2
464	EPHA1	EPH Receptor A1	Protein Coding	2
465	EPHA2	EPH Receptor A2	Protein Coding	2
466	EPHA3	EPH Receptor A3	Protein Coding	2
467	EPHA4	EPH Receptor A4	Protein Coding	2
468	EPHA5	EPH Receptor A5	Protein Coding	2
469	EPHA7	EPH Receptor A7	Protein Coding	2
470	EPHA8	EPH Receptor A8	Protein Coding	2
471	EPHB1	EPH Receptor B1	Protein Coding	2
472	EPHB2	EPH Receptor B2	Protein Coding	2
473	EPHB3	EPH Receptor B3	Protein Coding	2
474	EPHB4	EPH Receptor B4	Protein Coding	2
475	EPHB6	EPH Receptor B6	Protein Coding	2
476	EPOR	Erythropoietin Receptor	Protein Coding	2
477	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	Protein Coding	2
478	ERBB3	Erb-B2 Receptor Tyrosine Kinase 3	Protein Coding	2
479	ERBB4	Erb-B2 Receptor Tyrosine Kinase 4	Protein Coding	2
480	FLT3	Fms Related Receptor Tyrosine Kinase 3	Protein Coding	2
481	IGF2-AS	IGF2 Antisense RNA	RNA Gene	2
482	INSR	Insulin Receptor	Protein Coding	2
483	INSRR	Insulin Receptor Related Receptor	Protein Coding	2
484	LIFR	LIF Receptor Subunit Alpha	Protein Coding	2
485	LMTK2	Lemur Tyrosine Kinase 2	Protein Coding	2
486	LMTK3	Lemur Tyrosine Kinase 3	Protein Coding	2
487	MERTK	MER Proto-Oncogene, Tyrosine Kinase	Protein Coding	2
488	MST1R	Macrophage Stimulating 1 Receptor	Protein Coding	2
489	MUSK	Muscle Associated Receptor Tyrosine Kinase	Protein Coding	2
490	PTK7	Protein Tyrosine Kinase 7 (Inactive)	Protein Coding	2
491	ROR1	Receptor Tyrosine Kinase Like Orphan Receptor 1	Protein Coding	2
492	ROR2	Receptor Tyrosine Kinase Like Orphan Receptor 2	Protein Coding	2
493	ROS1	ROS Proto-Oncogene 1, Receptor Tyrosine Kinase	Protein Coding	2
494	RYK	Receptor Like Tyrosine Kinase	Protein Coding	2
495	ADCY10	Adenylate Cyclase 10	Protein Coding	2
496	TEK	TEK Receptor Tyrosine Kinase	Protein Coding	2
497	TIE1	Tyrosine Kinase With Immunoglobulin Like And EGF Like Domains 1	Protein Coding	2
498	TYRO3	TYRO3 Protein Tyrosine Kinase	Protein Coding	2
499	ANAPC1	Anaphase Promoting Complex Subunit 1	Protein Coding	2
500	ANAPC11	Anaphase Promoting Complex Subunit 11	Protein Coding	2
501	ANAPC2	Anaphase Promoting Complex Subunit 2	Protein Coding	2
502	ANAPC4	Anaphase Promoting Complex Subunit 4	Protein Coding	2
503	ANAPC5	Anaphase Promoting Complex Subunit 5	Protein Coding	2
504	ANAPC7	Anaphase Promoting Complex Subunit 7	Protein Coding	2
505	ANAPC10	Anaphase Promoting Complex Subunit 10	Protein Coding	2
506	CDC16	Cell Division Cycle 16	Protein Coding	2
507	CDC23	Cell Division Cycle 23	Protein Coding	2
508	CDC27	Cell Division Cycle 27	Protein Coding	2
509	ANAPC13	Anaphase Promoting Complex Subunit 13	Protein Coding	2
510	NGFR	Nerve Growth Factor Receptor	Protein Coding	2
511	CDK16	Cyclin Dependent Kinase 16	Protein Coding	2
512	PTK2B	Protein Tyrosine Kinase 2 Beta	Protein Coding	2
513	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	2
514	TGFBR1	Transforming Growth Factor Beta Receptor 1	Protein Coding	2
515	CHUK	Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex	Protein Coding	2
516	DHH	Desert Hedgehog Signaling Molecule	Protein Coding	2
517	GLI1	GLI Family Zinc Finger 1	Protein Coding	2
518	IHH	Indian Hedgehog Signaling Molecule	Protein Coding	2
519	NFKBIA	NFKB Inhibitor Alpha	Protein Coding	2
520	NFKBIB	NFKB Inhibitor Beta	Protein Coding	2
521	NFKBIE	NFKB Inhibitor Epsilon	Protein Coding	2
522	PTCH1	Patched 1	Protein Coding	2
523	PTCH2	Patched 2	Protein Coding	2
524	SMO	Smoothened, Frizzled Class Receptor	Protein Coding	2
525	CLCNKA	Chloride Voltage-Gated Channel Ka	Protein Coding	1
526	CLCNKB	Chloride Voltage-Gated Channel Kb	Protein Coding	1
527	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	1
528	SOS1	SOS Ras/Rac Guanine Nucleotide Exchange Factor 1	Protein Coding	1
529	SOS2	SOS Ras/Rho Guanine Nucleotide Exchange Factor 2	Protein Coding	1
530	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
531	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	1
532	AKT3	AKT Serine/Threonine Kinase 3	Protein Coding	1
533	ARRB1	Arrestin Beta 1	Protein Coding	1
534	ARRB2	Arrestin Beta 2	Protein Coding	1
535	CLEC14A	C-Type Lectin Domain Containing 14A	Protein Coding	1
536	DCC	DCC Netrin 1 Receptor	Protein Coding	1
537	RGS22	Regulator Of G Protein Signaling 22	Protein Coding	1
538	HBEGF	Heparin Binding EGF Like Growth Factor	Protein Coding	1
539	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	1
540	GLG1	Golgi Glycoprotein 1	Protein Coding	1
541	IGF2R	Insulin Like Growth Factor 2 Receptor	Protein Coding	1
542	IL2RA	Interleukin 2 Receptor Subunit Alpha	Protein Coding	1
543	MAPK11	Mitogen-Activated Protein Kinase 11	Protein Coding	1
544	MAPK12	Mitogen-Activated Protein Kinase 12	Protein Coding	1
545	MAPK13	Mitogen-Activated Protein Kinase 13	Protein Coding	1
546	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
547	MAPK6	Mitogen-Activated Protein Kinase 6	Protein Coding	1
548	MAPK7	Mitogen-Activated Protein Kinase 7	Protein Coding	1
549	MEP1B	Meprin A Subunit Beta	Protein Coding	1
550	NRP1	Neuropilin 1	Protein Coding	1
551	NRP2	Neuropilin 2	Protein Coding	1
552	OGFR	Opioid Growth Factor Receptor	Protein Coding	1
553	PIK3R5	Phosphoinositide-3-Kinase Regulatory Subunit 5	Protein Coding	1
554	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	1
555	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	1
556	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	1
557	PIK3R4	Phosphoinositide-3-Kinase Regulatory Subunit 4	Protein Coding	1
558	PKIA	CAMP-Dependent Protein Kinase Inhibitor Alpha	Protein Coding	1
559	PKIB	CAMP-Dependent Protein Kinase Inhibitor Beta	Protein Coding	1
560	PKIG	CAMP-Dependent Protein Kinase Inhibitor Gamma	Protein Coding	1
561	PLA2G10	Phospholipase A2 Group X	Protein Coding	1
562	PLA2G12A	Phospholipase A2 Group XIIA	Protein Coding	1
563	PLA2G12B	Phospholipase A2 Group XIIB	Protein Coding	1
564	PLA2G1B	Phospholipase A2 Group IB	Protein Coding	1
565	PLA2G2A	Phospholipase A2 Group IIA	Protein Coding	1
566	PLA2G2D	Phospholipase A2 Group IID	Protein Coding	1
567	PLA2G2E	Phospholipase A2 Group IIE	Protein Coding	1
568	PLA2G2F	Phospholipase A2 Group IIF	Protein Coding	1
569	PLA2G3	Phospholipase A2 Group III	Protein Coding	1
570	PLA2G4A	Phospholipase A2 Group IVA	Protein Coding	1
571	PLA2G4C	Phospholipase A2 Group IVC	Protein Coding	1
572	PLA2G4D	Phospholipase A2 Group IVD	Protein Coding	1
573	PLA2G5	Phospholipase A2 Group V	Protein Coding	1
574	PLA2G6	Phospholipase A2 Group VI	Protein Coding	1
575	PLA2G7	Phospholipase A2 Group VII	Protein Coding	1
576	RAP2A	RAP2A, Member Of RAS Oncogene Family	Protein Coding	1
577	RAPGEF4	Rap Guanine Nucleotide Exchange Factor 4	Protein Coding	1
578	RGS1	Regulator Of G Protein Signaling 1	Protein Coding	1
579	RGS10	Regulator Of G Protein Signaling 10	Protein Coding	1
580	RGS11	Regulator Of G Protein Signaling 11	Protein Coding	1
581	RGS12	Regulator Of G Protein Signaling 12	Protein Coding	1
582	RGS13	Regulator Of G Protein Signaling 13	Protein Coding	1
583	RGS14	Regulator Of G Protein Signaling 14	Protein Coding	1
584	RGS16	Regulator Of G Protein Signaling 16	Protein Coding	1
585	RGS17	Regulator Of G Protein Signaling 17	Protein Coding	1
586	RGS18	Regulator Of G Protein Signaling 18	Protein Coding	1
587	RGS19	Regulator Of G Protein Signaling 19	Protein Coding	1
588	RGS2	Regulator Of G Protein Signaling 2	Protein Coding	1
589	RGS20	Regulator Of G Protein Signaling 20	Protein Coding	1
590	RGS21	Regulator Of G Protein Signaling 21	Protein Coding	1
591	RGS3	Regulator Of G Protein Signaling 3	Protein Coding	1
592	RGS4	Regulator Of G Protein Signaling 4	Protein Coding	1
593	RGS5	Regulator Of G Protein Signaling 5	Protein Coding	1
594	RGS6	Regulator Of G Protein Signaling 6	Protein Coding	1
595	RGS7	Regulator Of G Protein Signaling 7	Protein Coding	1
596	RGS8	Regulator Of G Protein Signaling 8	Protein Coding	1
597	RGS9	Regulator Of G Protein Signaling 9	Protein Coding	1
598	RPS6KB1	Ribosomal Protein S6 Kinase B1	Protein Coding	1
599	TGFBR3	Transforming Growth Factor Beta Receptor 3	Protein Coding	1
600	STK36	Serine/Threonine Kinase 36	Protein Coding	1
601	SUFU	SUFU Negative Regulator Of Hedgehog Signaling	Protein Coding	1
602	CTNNB1	Catenin Beta 1	Protein Coding	1
603	H1-0	H1.0 Linker Histone	Protein Coding	1
604	H1-10	H1.10 Linker Histone	Protein Coding	1
605	H3-3A	H3.3 Histone A	Protein Coding	1
606	H3-3B	H3.3 Histone B	Protein Coding	1
607	H1-1	H1.1 Linker Histone, Cluster Member	Protein Coding	1
608	H1-5	H1.5 Linker Histone, Cluster Member	Protein Coding	1
609	H1-2	H1.2 Linker Histone, Cluster Member	Protein Coding	1
610	H1-3	H1.3 Linker Histone, Cluster Member	Protein Coding	1
611	H1-4	H1.4 Linker Histone, Cluster Member	Protein Coding	1
612	H1-6	H1.6 Linker Histone, Cluster Member	Protein Coding	1
613	H3C1	H3 Clustered Histone 1	Protein Coding	1
614	H3C2	H3 Clustered Histone 2	Protein Coding	1
615	H3C3	H3 Clustered Histone 3	Protein Coding	1
616	H3C4	H3 Clustered Histone 4	Protein Coding	1
617	H3C6	H3 Clustered Histone 6	Protein Coding	1
618	H3C7	H3 Clustered Histone 7	Protein Coding	1
619	H3C8	H3 Clustered Histone 8	Protein Coding	1
620	H3C10	H3 Clustered Histone 10	Protein Coding	1
621	H3C11	H3 Clustered Histone 11	Protein Coding	1
622	H3C12	H3 Clustered Histone 12	Protein Coding	1
623	H3-4	H3.4 Histone, Cluster Member	Protein Coding	1
624	SMAD3	SMAD Family Member 3	Protein Coding	1
625	SMAD4	SMAD Family Member 4	Protein Coding	1
626	MYLK	Myosin Light Chain Kinase	Protein Coding	1
627	PTK2	Protein Tyrosine Kinase 2	Protein Coding	1
628	PXN	Paxillin	Protein Coding	1
629	TGFBR2	Transforming Growth Factor Beta Receptor 2	Protein Coding	1
630	TH	Tyrosine Hydroxylase	Protein Coding	1

Disorders associated with Activation of cAMP-Dependent PKA SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Noonan syndrome 1	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, MRAS, NRAS, RAF1, RRAS, RRAS2, SOS1, SOS2	10.59
2	Rasopathy	Enrichment	BRAF, CLCN1, HRAS, KRAS, MAP2K1, MAP2K2, MRAS, NRAS, RAF1, RRAS2, SOS1, SOS2	10.46
3	Brugada syndrome	Enrichment	AKAP9, CACNA1C, CACNA2D1, CACNB2, SCN10A, SCN1B, SCN2B, SCN3B, SCN5A, SCNN1A	9.39
4	Lung non-small cell carcinoma	Enrichment	BRAF, EGFR, ERBB2, HRAS, KRAS, MAP2K1, NRAS	8.27
5	Noonan syndrome and noonan-related syndrome	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NRAS, RAF1, SOS1	7.77
6	Long qt syndrome 1	Enrichment	AKAP9, CACNA1C, CALM1, CALM2, CALM3, ITPR3, SCN10A, SCN4B, SCN5A	7.40
7	Pilomyxoid astrocytoma	Enrichment	BRAF, FGFR1, KRAS, NTRK2, RAF1	6.37
8	Cardiofaciocutaneous syndrome 1	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	6.13
9	Cardiofaciocutaneous syndrome	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	6.13
10	Melanocytic nevus syndrome, congenital	Enrichment	ALK, BRAF, HRAS, NRAS, RAF1	5.95
11	Loeys-dietz syndrome	Enrichment	SMAD3, TGFB2, TGFB3, TGFBR1, TGFBR2	5.90
12	Neuropathy, hereditary sensory and autonomic, type v	Enrichment	NGF, NTRK1, SCN10A, SCN11A, SCN9A	5.88
13	Lung cancer susceptibility 3	Enrichment	BRAF, EGFR, ERBB2, FGF10, KRAS, ROS1	5.81
14	Phosphorylase kinase deficiency	Enrichment	PHKA1, PHKA2, PHKB, PHKG2	5.68
15	Microform holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1, PTCH1, SUFU	5.41
16	Undetermined early-onset epileptic encephalopathy	Enrichment	CACNA1A, CACNA1B, CACNA2D1, FGF12, NTRK2, PPP3CA, SCN1A, SCN1B, SCN3A, SCN8A, YWHAG	5.29
17	Cardiac conduction defect	Enrichment	CACNA1C, PLN, RYR2, SCN1B, SCN5A	5.13
18	Lung squamous cell carcinoma	Enrichment	ALK, EGFR, FGFR3, KRAS	4.98
19	Long qt syndrome	Enrichment	AKAP9, CACNA1C, CACNA1S, CALM1, CALM2, RYR2, SCN5A	4.96
20	Differentiated thyroid carcinoma	Enrichment	ALK, BRAF, HRAS, KRAS, NRAS, NTRK1, NTRK3	4.79
21	Liddle syndrome 1	Enrichment	SCNN1A, SCNN1B, SCNN1G	4.77
22	Pseudohypoaldosteronism, type ib1, autosomal recessive	Enrichment	SCNN1A, SCNN1B, SCNN1G	4.77
23	Hereditary sodium channelopathy-related small fibers neuropathy	Enrichment	SCN10A, SCN11A, SCN9A	4.77
24	Cone-rod dystrophy 6	Enrichment	CACNA1F, CACNA2D4, CNGB3, GNAT2, KCNV2	4.74
25	Nevus, epidermal	Enrichment	FGFR3, HRAS, KRAS, NRAS	4.62
26	Familial atrial fibrillation	Enrichment	MYL4, SCN1B, SCN2B, SCN3B, SCN4B, SCN5A	4.60
27	Lacrimoauriculodentodigital syndrome 1	Enrichment	FGF10, FGFR2, FGFR3	4.60
28	Langerhans cell histiocytosis	Enrichment	BRAF, MAP2K1, NRAS	4.60
29	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3, RYR2	4.56
30	Developmental and epileptic encephalopathy	Enrichment	CACNA1E, CACNA2D2, GNAO1, SCN1A, SCN2A, SCN3A, SCN8A	4.51
31	Developmental and epileptic encephalopathy 14	Enrichment	KCNT1, PLCB1, SCN1A, SCN2A	4.31
32	Sudden infant death syndrome	Enrichment	CALM2, PLN, SCN1A, SCN5A, TNNI3	4.28
33	Noonan syndrome 3	Enrichment	HRAS, KRAS, RAF1, SOS1	4.23
34	Erythermalgia, primary	Enrichment	SCN10A, SCN11A, SCN9A	4.18
35	Ventricular fibrillation, paroxysmal familial, 1	Enrichment	CACNA1C, RYR2, SCN5A	4.18
36	Idiopathic bronchiectasis	Enrichment	SCNN1A, SCNN1B, SCNN1G	4.18
37	Lobar holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1, PTCH1	4.14
38	Autosomal dominant non-syndromic intellectual disability	Enrichment	CACNA1I, CACNG2, CAMK2A, CAMK2B, ERBB4, GNB1, PPP3CA, SCN8A, YWHAZ	4.11
39	Dravet syndrome	Enrichment	SCN1A, SCN1B, SCN2A, SCN9A	4.10
40	Arteriovenous malformation	Enrichment	EPHB4, HRAS, MAP2K1, TEK	4.08
41	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS, KRAS, NRAS	4.01
42	Giant cell glioblastoma	Enrichment	EGFR, FGFR1, FGFR3, NFKBIA, ROS1	4.00
43	Generalized epilepsy with febrile seizures plus	Enrichment	FGF13, SCN1A, SCN1B, SCN2A, SCN9A	3.99
44	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	MYLK, SMAD3, SMAD4, TGFB2, TGFB3, TGFBR1, TGFBR2	3.93
45	Semilobar holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1, PTCH1	3.87
46	Myopathy, x-linked, with excessive autophagy	Enrichment	EPHB4, HRAS, MAP2K1, TEK	3.87
47	Paroxysmal extreme pain disorder	Enrichment	SCN10A, SCN11A, SCN9A	3.79
48	Heart conduction disease	Enrichment	CACNA1C, RYR2, SCN5A	3.79
49	Cardiac arrest	Enrichment	CACNA2D1, PLN, SCN5A	3.79
50	Bladder cancer	Enrichment	EGFR, ERBB2, ERBB3, FGFR3, HRAS, KRAS	3.78
51	Arteriovenous malformations of the brain	Enrichment	BRAF, EGFR, IL6, KRAS, TIMP3	3.75
52	Primary hypereosinophilic syndrome	Enrichment	FGFR1, PDGFRA, PDGFRB	3.62
53	Congenital stationary night blindness	Enrichment	CACNA1F, CACNA2D4, GNAT1, GNB3, GRK1	3.60
54	Lung cancer	Enrichment	ALK, BRAF, EGFR, ERBB2, KRAS, MET	3.53
55	Lip and oral cavity carcinoma	Enrichment	BRAF, EGFR, HRAS, KIT	3.52
56	Hypokalemic periodic paralysis, type 1	Enrichment	CACNA1S, CLCN1, SCN4A	3.50
57	Cerebral palsy	Enrichment	ADD3, CACNA1A, CACNA1C, CLCN1, CLCN2, GNB1	3.35
58	Basal cell nevus syndrome 1	Enrichment	PTCH1, PTCH2, SUFU	3.33
59	Testicular germ cell tumor	Enrichment	FGFR3, KIT, KITLG	3.33
60	Brugada syndrome 1	Enrichment	CACNA2D1, SCN10A, SCN5A	3.26
61	Gallbladder cancer	Enrichment	BRAF, CTNNB1, SMAD4	3.26
62	Benign epilepsy with centrotemporal spikes	Enrichment	KCNT1, PLCB1, SCN1A, SCN1B, SCN2A, SCN9A	3.23
63	Batten-turner congenital myopathy	Enrichment	CLCN1, SCN4A	3.18
64	Loeys-dietz syndrome 2	Enrichment	TGFBR1, TGFBR2	3.18
65	Pigmented nodular adrenocortical disease, primary, 1	Enrichment	GNAS, PRKAR1A	3.18
66	Achromatopsia 3	Enrichment	CNGA3, CNGB3	3.18
67	Loeys-dietz syndrome 4	Enrichment	TGFB2, TGFB3	3.18
68	Bryant-li-bhoj neurodevelopmental syndrome 2	Enrichment	H3-3A, H3-3B	3.18
69	Malignant migrating partial seizures of infancy	Enrichment	KCNT1, SCN2A	3.18
70	Glycogen storage disease due to liver phosphorylase kinase deficiency	Enrichment	PHKA2, PHKG2	3.18
71	Distal arthrogryposis	Enrichment	MYL11, RYR1, SCN4A, SCN5A, SCN8A, TNNI2	3.18
72	Colorectal cancer	Enrichment	AKT1, BRAF, DCC, FGFR2, FGFR3, IGF2, MET, NRAS, PIK3R1, PLA2G2A, SRC	3.17
73	Centralopathic epilepsy	Enrichment	KCNT1, PLCB1, SCN1A, SCN1B, SCN2A, SCN9A	3.12
74	Ovarian cancer	Enrichment	ALK, EGFR, ERBB2, KIT, KRAS, MET, NTRK1, PDGFRA, PTCH1, RRAS2	3.11
75	Septopreoptic holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1, PTCH1	3.11
76	Midline interhemispheric variant of holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1, PTCH1	3.11
77	Thyroid cancer, nonmedullary, 2	Enrichment	BRAF, HRAS, NRAS	3.09
78	Capillary malformation-arteriovenous malformation 1	Enrichment	EPHB4, KRAS, MAP2K1	3.09
79	Follicular thyroid carcinoma	Enrichment	BRAF, HRAS, NRAS	3.09
80	Lymphatic malformation 1	Enrichment	EPHB4, FLT4	3.06
81	Intracranial hypertension, idiopathic	Enrichment	EPHB4, FLT4	3.06
82	Pfeiffer syndrome	Enrichment	FGFR1, FGFR2	3.06
83	Jackson-weiss syndrome	Enrichment	FGFR1, FGFR2	3.06
84	Encephalocraniocutaneous lipomatosis	Enrichment	FGFR1, KRAS	3.06
85	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS, NRAS	3.06
86	Angioma, tufted	Enrichment	GNA14, KDR	3.06
87	Hereditary lymphedema i	Enrichment	EPHB4, FLT4	3.06
88	Gliosarcoma	Enrichment	EGFR, FGFR1, FGFR3, NFKBIA	2.99
89	Ellis-van creveld syndrome	Enrichment	GLI1, PRKACA, PRKACB	2.90
90	Primary hyperaldosteronism	Enrichment	BRAF, CACNA1H, GNAS	2.90
91	Alobar holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1, PTCH1	2.89
92	Pulmonic stenosis	Enrichment	BRAF, SOS1	2.87
93	Hirschsprung disease 1	Enrichment	ERBB2, ERBB3, IHH, NRG3, SMO	2.85
94	Normosmic congenital hypogonadotropic hypogonadism	Enrichment	FGF17, FGF8, FGFR1, GNRH1	2.79
95	Marfan syndrome	Enrichment	TGFB2, TGFBR1, TGFBR2	2.75
96	Achromatopsia	Enrichment	CNGA3, CNGB3, GNAT2	2.75
97	Kallmann syndrome	Enrichment	DCC, FGF17, FGF8, FGFR1, SEMA3A	2.73
98	Eye disease	Enrichment	CACNA1F, CACNA2D4, CNGA3, CNGB3, GNAT2	2.72
99	Glycogen storage disease ixd	Enrichment	PHKA1, PHKG1	2.71
100	Generalized epilepsy with febrile seizures plus, type 1	Enrichment	SCN1A, SCN1B	2.71
101	Neurodevelopmental disorder with hypotonia, language delay, and skeletal defects with or without seizures	Enrichment	CACNA1A, CACNA1C	2.71
102	Tethered spinal cord syndrome	Enrichment	BRAF, CREBBP	2.71
103	Loeys-dietz syndrome 1	Enrichment	TGFBR1, TGFBR2	2.71
104	Melanoma of soft tissue	Enrichment	ATF1, CREB1	2.71
105	Anastomosing haemangioma	Enrichment	GNA11, GNA14	2.71
106	Hereditary episodic ataxia	Enrichment	CACNA1A, SCN2A	2.71
107	Fetal akinesia deformation sequence 1	Enrichment	MUSK, ROR2, RYR1, SCN4A, SCN5A, SCN8A	2.67
108	Glycogen storage disease	Enrichment	GYS1, GYS2, PYGM	2.62
109	Movement disease	Enrichment	CLCN6, GNAO1, SCN2A	2.62
110	Brachydactyly, type a1	Enrichment	GDF5, IHH	2.60
111	Crouzon syndrome	Enrichment	FGFR2, FGFR3	2.60
112	Large congenital melanocytic nevus	Enrichment	HRAS, NRAS	2.60
113	Bronchopulmonary dysplasia	Enrichment	MUSK, RYR1	2.60
114	Testicular germ cell cancer	Enrichment	FGFR3, KIT	2.60
115	Spermatocytoma	Enrichment	FGFR3, HRAS	2.60
116	Cone dystrophy	Enrichment	CACNA2D4, CNGA3, GNAT2, KCNV2	2.52
117	Epilepsy	Enrichment	KCNT1, SCN1A, SCN2A, SCN3A, SCN8A	2.46
118	Aland island eye disease	Enrichment	CACNA1F, PHKA2	2.42
119	Auriculocondylar syndrome 1	Enrichment	GNAI3, PLCB4	2.42
120	Hyperkalemic periodic paralysis	Enrichment	CLCN1, SCN4A	2.42
121	Developmental and epileptic encephalopathy 12	Enrichment	PLCB1, SCN2A	2.42
122	Achromatopsia 4	Enrichment	GNAI3, GNAT2	2.42
123	Developmental and epileptic encephalopathy 52	Enrichment	CACNA1A, SCN1B	2.42
124	Aortic aneurysm	Enrichment	SMAD3, TGFBR1	2.42
125	Craniopharyngioma	Enrichment	BRAF, CTNNB1	2.42
126	Noonan syndrome with multiple lentigines	Enrichment	BRAF, RAF1	2.42
127	Malignant hyperthermia	Enrichment	CACNA1S, RYR1	2.42
128	Episodic ataxia	Enrichment	CACNA1A, SCN2A	2.42
129	Hereditary progressive cardiac conduction defect	Enrichment	SCN1B, SCN5A	2.42
130	Familial or sporadic hemiplegic migraine	Enrichment	CACNA1A, SCN1A	2.42
131	Paroxysmal familial ventricular fibrillation	Enrichment	RYR2, SCN5A	2.42
132	Familial sick sinus syndrome	Enrichment	GNB2, SCN5A	2.42
133	Hypertension, essential	Enrichment	ADD1, GNB3, NOS3, RGS5	2.40
134	Bartter syndrome type 4	Enrichment	CLCNKA, CLCNKB	2.40
135	Juvenile myelomonocytic leukemia	Enrichment	KRAS, NRAS, RRAS	2.34
136	Meningioma	Enrichment	PDGFB, SMO, SUFU	2.34
137	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	GNA11, PIK3R1	2.33
138	Medulloblastoma	Enrichment	CTNNB1, PTCH1, PTCH2	2.30
139	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	PLN, RYR2, TGFB3	2.30
140	Brachydactyly, type a2	Enrichment	BMP2, GDF5	2.30
141	Glaucoma 3, primary infantile, b	Enrichment	LTBP2, TEK	2.30
142	Saethre-chotzen syndrome	Enrichment	FGFR2, FGFR3	2.30
143	Cholangiocarcinoma	Enrichment	PTPN3, ROS1	2.30
144	Multiple synostoses syndrome	Enrichment	GDF5, GDF6	2.30
145	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	KRAS, NRAS	2.30
146	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	FLT3, KIT	2.30
147	Glioma	Enrichment	FGFR2, NTRK3	2.30
148	West syndrome	Enrichment	GNAO1, PLCB1, SCN1A, SCN2A, SCN8A	2.28
149	Nk-cell enteropathy	Enrichment	AXL, ERBB4, IGF1R	2.24
150	Myeloma, multiple	Enrichment	BRAF, CREBBP, FGFR3, FLT3, KRAS, MST1R	2.23
151	Convulsions, familial infantile, with paroxysmal choreoathetosis	Enrichment	PDE2A, SCN8A	2.20
152	Self-limited infantile epilepsy	Enrichment	SCN2A, SCN8A	2.20
153	Arrhythmogenic right ventricular cardiomyopathy	Enrichment	RYR1, RYR2, SCN5A	2.13
154	Bartter syndrome, type 4b, neonatal, with sensorineural deafness	Enrichment	CLCNKA, CLCNKB	2.11
155	Cone-rod dystrophy 2	Enrichment	CACNA1F, CACNA2D4, CNGA1, CNGA3, CNGB3, KCNV2	2.10
156	Hemifacial hyperplasia	Enrichment	FGFR2, FGFR3	2.09
157	Insulin-like growth factor i	Enrichment	IGF1, IGF1R	2.09
158	Ventricular septal defect 1	Enrichment	BMP2, BMP7	2.09
159	Pre-eclampsia	Enrichment	FLT1, NOS3	2.09
160	Acute myeloid leukemia with maturation	Enrichment	FLT3, KIT	2.09
161	Holoprosencephaly	Enrichment	FGF8, FGFR1	2.09
162	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	FLT3, KIT	2.09
163	Mirror movements 1	Enrichment	DCC, NTN1	2.04
164	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	AKT3, PIK3R2	2.04
165	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	AKT3, PIK3R2	2.04
166	Melanoma, uveal	Enrichment	GNA11, PLCB4	2.03
167	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1, RYR2	2.03
168	Basal cell carcinoma 1	Enrichment	PTCH1, PTCH2	2.03
169	Adrenocortical carcinoma	Enrichment	CTNNB1, PRKAR1A	2.03
170	Familial hypertrophic cardiomyopathy	Enrichment	MYL2, MYL3, RAF1, TNNI3	2.01
171	Early infantile developmental and epileptic encephalopathy	Enrichment	GNAO1, SCN1B, SCN2A	1.99
172	Rhabdomyosarcoma	Enrichment	ALK, HRAS, PTCH1	1.97
173	Atrial septal defect 1	Enrichment	BMP2, TGFB2	1.92
174	Hemihyperplasia, isolated	Enrichment	IGF2, RHOA	1.92
175	Holoprosencephaly 1	Enrichment	FGF8, FGFR1	1.92
176	Hemangioma, capillary infantile	Enrichment	FLT4, KDR	1.92
177	46,xy disorder of sex development	Enrichment	FGFR3, INSR	1.92
178	Left ventricular noncompaction	Enrichment	RAF1, RYR2, SCN5A, TNNI3	1.92
179	Congenital myopathy	Enrichment	CACNA1S, RYR1, SCN4A	1.92
180	Ehlers-danlos syndrome	Enrichment	SMAD3, TGFB2, TGFBR2	1.92
181	Non-immune hydrops fetalis	Enrichment	EPHB4, FLT4, HRAS, KRAS	1.91
182	Focal epilepsy	Enrichment	SCN2A, SCN8A	1.90
183	Familial isolated restrictive cardiomyopathy	Enrichment	MYL2, TNNI3	1.90
184	Hemimegalencephaly	Enrichment	AKT3, MTOR	1.83
185	Familial cerebral saccular aneurysm	Enrichment	ANGPTL6, TGFBR3	1.83
186	Glaucoma 3, primary congenital, a	Enrichment	LTBP2, TEK	1.78
187	Gastrointestinal stromal tumor	Enrichment	KIT, PDGFRA	1.78
188	Leukemia, chronic myeloid	Enrichment	KRAS, NRAS	1.78
189	Glioma susceptibility 1	Enrichment	H3-3A, H3C1	1.78
190	Lennox-gastaut syndrome	Enrichment	CACNA1A, SCN1A	1.78
191	Alternating hemiplegia of childhood	Enrichment	CACNA1A, SCN2A	1.78
192	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1, RYR2	1.78
193	Choreatic disease	Enrichment	GNAO1, PDE2A	1.78
194	Dilated cardiomyopathy	Enrichment	BRAF, MYL2, PLN, RAF1, SCN5A, TNNI3	1.77
195	Rare genetic intellectual disability	Enrichment	CREBBP, GNAO1, MTOR	1.70
196	Cardiomyopathy, familial hypertrophic, 4	Enrichment	BRAF, TNNI3	1.68
197	Familial thoracic aortic aneurysm and dissection	Enrichment	MYLK, SMAD3	1.68
198	Hydrops fetalis	Enrichment	RYR1, RYR3	1.68
199	Breast adenocarcinoma	Enrichment	AKT1, KRAS	1.67
200	Arthrogryposis, distal, type 1a	Enrichment	MET, TNNI2	1.67
201	Basal ganglia calcification, idiopathic, 1	Enrichment	PDGFB, PDGFRB	1.67
202	Hemochromatosis, type 1	Enrichment	BMP2, BMP6	1.67
203	Cardiomyopathy, familial hypertrophic, 1	Enrichment	CACNA1C, RAF1, TNNI3	1.64
204	Hypertrophic cardiomyopathy	Enrichment	MYL2, MYL3, PLN, TNNI3	1.62
205	Developmental and epileptic encephalopathy 1	Enrichment	GNAO1, SCN1A, SCN8A	1.59
206	Anhidrosis, isolated, with normal sweat glands	Enrichment	ITPR2	1.59
207	Osteopetrosis, autosomal dominant 2	Enrichment	CLCN7	1.59
208	Hypertension and brachydactyly syndrome	Enrichment	PDE3A	1.59
209	Hypocalciuric hypercalcemia, familial, type ii	Enrichment	GNA11	1.59
210	Acrodysostosis 1 with or without hormone resistance	Enrichment	PRKAR1A	1.59
211	Thyrotoxic periodic paralysis 1	Enrichment	CACNA1S	1.59
212	46,xy sex reversal 7	Enrichment	DHH	1.59
213	Glycogen storage disease vi	Enrichment	PYGL	1.59
214	Achromatopsia 2	Enrichment	CNGA3	1.59
215	Glycogen storage disease v	Enrichment	PYGM	1.59
216	Curry-jones syndrome	Enrichment	SMO	1.59
217	Noonan syndrome 5	Enrichment	RAF1	1.59
218	Cardiomyopathy, dilated, 2a	Enrichment	TNNI3	1.59
219	Cone dystrophy with supernormal rod responses	Enrichment	KCNV2	1.59
220	Pseudohypoparathyroidism, type ic	Enrichment	GNAS	1.59
221	Epilepsy, idiopathic generalized 9	Enrichment	CACNB4	1.59
222	Carney complex, type 1	Enrichment	PRKAR1A	1.59
223	Brugada syndrome 4	Enrichment	CACNB2	1.59
224	Cardiomyopathy, familial hypertrophic, 8	Enrichment	MYL3	1.59
225	Schilbach-rott syndrome	Enrichment	PTCH1	1.59
226	Scalp-ear-nipple syndrome	Enrichment	KCTD1	1.59
227	Brugada syndrome 5	Enrichment	SCN1B	1.59
228	Melorheostosis, isolated	Enrichment	MAP2K1	1.59
229	Osseous heteroplasia, progressive	Enrichment	GNAS	1.59
230	Cardiomyopathy, familial hypertrophic, 7	Enrichment	TNNI3	1.59
231	Noonan syndrome 7	Enrichment	BRAF	1.59
232	Leopard syndrome 3	Enrichment	BRAF	1.59
233	Glycogen storage disease ixc	Enrichment	PHKG2	1.59
234	Bronchiectasis with or without elevated sweat chloride 2	Enrichment	SCNN1A	1.59
235	Bronchiectasis with or without elevated sweat chloride 3	Enrichment	SCNN1G	1.59
236	Nail disorder, nonsyndromic congenital, 3	Enrichment	PLCD1	1.59
237	Long qt syndrome 10	Enrichment	SCN4B	1.59
238	Polydactyly, preaxial i	Enrichment	GLI1	1.59
239	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	1.59
240	Multiple self-healing squamous epithelioma	Enrichment	TGFBR1	1.59
241	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	1.59
242	Episodic pain syndrome, familial, 3	Enrichment	SCN11A	1.59
243	Dyskinesia with orofacial involvement, autosomal dominant	Enrichment	ADCY5	1.59
244	Developmental and epileptic encephalopathy 11	Enrichment	SCN2A	1.59
245	Fetal encasement syndrome	Enrichment	CHUK	1.59
246	Neuropathy, hereditary sensory and autonomic, type vii	Enrichment	SCN11A	1.59
247	Neurodevelopmental disorder with involuntary movements	Enrichment	GNAO1	1.59
248	Deafness, autosomal recessive 44	Enrichment	ADCY1	1.59
249	Episodic ataxia, type 5	Enrichment	CACNB4	1.59
250	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	1.59
251	Ventricular tachycardia, familial	Enrichment	GNAI2	1.59
252	Acth-independent macronodular adrenal hyperplasia 1	Enrichment	GNAS	1.59
253	Atrial fibrillation, familial, 14	Enrichment	SCN2B	1.59
254	Neurodevelopmental disorder with hypotonia and dysmorphic facies	Enrichment	GNB2	1.59
255	Neurodevelopmental disorder with seizures and brain abnormalities	Enrichment	CLCN3	1.59
256	Noonan syndrome 13	Enrichment	MAPK1	1.59
257	Spondylometaphyseal dysplasia with corneal dystrophy	Enrichment	PLCB3	1.59
258	Deafness, autosomal recessive 103	Enrichment	CLIC5	1.59
259	Pseudohypoaldosteronism, type ib2, autosomal recessive	Enrichment	SCNN1B	1.59
260	Congenital myopathy 20	Enrichment	RYR3	1.59
261	Neurodevelopmental disorder with hyperkinetic movements and dyskinesia	Enrichment	ADCY5	1.59
262	Polydactyly, postaxial, type a8	Enrichment	GLI1	1.59
263	Pituitary adenoma 3, multiple types	Enrichment	GNAS	1.59
264	Charcot-marie-tooth disease, demyelinating, type 1j	Enrichment	ITPR3	1.59
265	Neurodevelopmental disorder with speech impairment and with or without seizures	Enrichment	CACNA1I	1.59
266	Liddle syndrome 2	Enrichment	SCNN1G	1.59
267	Congenital myopathy 18	Enrichment	CACNA1S	1.59
268	Hypopigmentation, organomegaly, and delayed myelination and development	Enrichment	CLCN7	1.59
269	Developmental and epileptic encephalopathy 91	Enrichment	PPP3CA	1.59
270	Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual development	Enrichment	PPP3CA	1.59
271	Myoclonus, familial, 2	Enrichment	SCN8A	1.59
272	Spermatogenic failure 79	Enrichment	KCNU1	1.59
273	Raynaud-claes syndrome	Enrichment	CLCN4	1.59
274	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	1.59
275	Developmental and epileptic encephalopathy 62	Enrichment	SCN3A	1.59
276	Liddle syndrome 3	Enrichment	SCNN1A	1.59
277	Mirror movements 4	Enrichment	NTN1	1.59
278	Auriculocondylar syndrome 2a	Enrichment	PLCB4	1.59
279	Cone-rod dystrophy, x-linked, 3	Enrichment	CACNA1F	1.59
280	Retinal cone dystrophy 4	Enrichment	CACNA2D4	1.59
281	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	1.59
282	Intellectual developmental disorder with paroxysmal dyskinesia or seizures	Enrichment	PDE2A	1.59
283	Atrial fibrillation, familial, 13	Enrichment	SCN1B	1.59
284	Cerebral palsy, spastic quadriplegic, 3	Enrichment	ADD3	1.59
285	Neurodevelopmental disorder with hypotonia, impaired speech, and behavioral abnormalities	Enrichment	GNAI1	1.59
286	Myxoma, intracardiac	Enrichment	PRKAR1A	1.59
287	Atrial fibrillation, familial, 18	Enrichment	MYL4	1.59
288	Developmental and epileptic encephalopathy 17	Enrichment	GNAO1	1.59
289	Primary aldosteronism, seizures, and neurologic abnormalities	Enrichment	CACNA1D	1.59
290	Dyskinesia with orofacial involvement, autosomal recessive	Enrichment	ADCY5	1.59
291	Lymphangioma	Enrichment	BRAF	1.59
292	Long qt syndrome 11	Enrichment	AKAP9	1.59
293	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	1.59
294	Brugada syndrome 3	Enrichment	CACNA1C	1.59
295	Epilepsy, childhood absence 6	Enrichment	CACNA1H	1.59
296	Camurati-engelmann disease 2	Enrichment	TGFB2	1.59
297	Rahman syndrome	Enrichment	H1-4	1.59
298	Malignant hyperthermia 5	Enrichment	CACNA1S	1.59
299	Acrocapitofemoral dysplasia	Enrichment	IHH	1.59
300	Phace association	Enrichment	BRAF	1.59
301	Spinocerebellar ataxia 14	Enrichment	PRKCG	1.59
302	Melorheostosis	Enrichment	MAP2K1	1.59
303	Epilepsy, idiopathic generalized 11	Enrichment	CLCN2	1.59
304	Night blindness, congenital stationary, autosomal dominant 3	Enrichment	GNAT1	1.59
305	Colorectal cancer, hereditary nonpolyposis, type 6	Enrichment	TGFBR2	1.59
306	Episodic ataxia, type 9	Enrichment	SCN2A	1.59
307	Leopard syndrome 2	Enrichment	RAF1	1.59
308	Intellectual developmental disorder, autosomal dominant 10	Enrichment	CACNG2	1.59
309	Sinoatrial node dysfunction and deafness	Enrichment	CACNA1D	1.59
310	Episodic pain syndrome, familial, 2	Enrichment	SCN10A	1.59
311	Dystonia 25	Enrichment	GNAL	1.59
312	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	1.59
313	Autoinflammation, antibody deficiency, and immune dysregulation	Enrichment	PLCG2	1.59
314	Thrombocytopenia 11 with multiple congenital anomalies and dysmorphic facies	Enrichment	RAP1B	1.59
315	Night blindness, congenital stationary, type 1g	Enrichment	GNAT1	1.59
316	Long qt syndrome 16	Enrichment	CALM3	1.59
317	Hypocalcemia, autosomal dominant 2	Enrichment	GNA11	1.59
318	Pulmonary hypertension, primary, 4	Enrichment	KCNK3	1.59
319	Benign familial infantile epilepsy	Enrichment	SCN2A	1.59
320	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	1.59
321	Brugada syndrome 7	Enrichment	SCN3B	1.59
322	Charcot-marie-tooth disease, dominant intermediate f	Enrichment	GNB4	1.59
323	Immunodeficiency 105, severe combined	Enrichment	PTPRC	1.59
324	Spinocerebellar ataxia 42	Enrichment	CACNA1G	1.59
325	Developmental and epileptic encephalopathy 110	Enrichment	CACNA2D1	1.59
326	Disorders of gnas inactivation	Enrichment	GNAS	1.59
327	Retinitis pigmentosa 45	Enrichment	CNGB1	1.59
328	Familial cold autoinflammatory syndrome 3	Enrichment	PLCG2	1.59
329	Congenital heart defects and ectodermal dysplasia	Enrichment	PRKD1	1.59
330	Developmental and epileptic encephalopathy 56	Enrichment	YWHAG	1.59
331	Epilepsy, familial focal, with variable foci 4	Enrichment	SCN3A	1.59
332	Spinocerebellar ataxia 42, early-onset, severe, with neurodevelopmental deficits	Enrichment	CACNA1G	1.59
333	Loeys-dietz syndrome 5	Enrichment	TGFB3	1.59
334	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	1.59
335	Developmental and epileptic encephalopathy 69	Enrichment	CACNA1E	1.59
336	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	1.59
337	Bryant-li-bhoj neurodevelopmental syndrome 1	Enrichment	H3-3A	1.59
338	Intellectual developmental disorder, autosomal dominant 42	Enrichment	GNB1	1.59
339	Hyperaldosteronism, familial, type iv	Enrichment	CACNA1H	1.59
340	Deafness, autosomal dominant 74	Enrichment	PDE1C	1.59
341	Bartsocas-papas syndrome 2	Enrichment	CHUK	1.59
342	Sick sinus syndrome 4	Enrichment	GNB2	1.59
343	Menke-hennekam syndrome 1	Enrichment	CREBBP	1.59
344	Congenital myopathy 14	Enrichment	MYL1	1.59
345	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	1.59
346	Cd45 deficiency	Enrichment	PTPRC	1.59
347	Developmental and epileptic encephalopathy 57	Enrichment	KCNT2	1.59
348	Ceroid lipofuscinosis, neuronal, 15	Enrichment	CLCN6	1.59
349	Muscular channelopathy	Enrichment	SCN4A	1.59
350	Trigonitis	Enrichment	RAF1	1.59
351	Neurodevelopmental disorder with hypotonia and brain abnormalities	Enrichment	CLCN3	1.59
352	Auriculocondylar syndrome 2b	Enrichment	PLCB4	1.59
353	Congenital myopathy with myasthenic-like onset	Enrichment	RYR1	1.59
354	Pseudohypoaldosteronism, type ib3, autosomal recessive	Enrichment	SCNN1G	1.59
355	Adenoid ameloblastoma	Enrichment	CTNNB1	1.59
356	Long qt syndrome 15	Enrichment	CALM2	1.59
357	Spermatogenic failure 82	Enrichment	AKAP3	1.59
358	Heritable thoracic aortic disease	Enrichment	SMAD4	1.59
359	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	1.59
360	Progressive myoclonus epilepsy 3	Enrichment	KCTD7	1.59
361	Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy	Enrichment	ITPR3	1.59
362	Prkar1b-related neurodegenerative dementia with intermediate filaments	Enrichment	PRKAR1B	1.59
363	Conn's syndrome	Enrichment	CACNA1H	1.59
364	Turner syndrome	Enrichment	PTCH1	1.59
365	X-linked intellectual disability-cardiomegaly-congestive heart failure syndrome	Enrichment	CLIC2	1.59
366	Sporadic hemiplegic migraine	Enrichment	CACNA1A	1.59
367	Syringocystadenoma papilliferum	Enrichment	BRAF	1.59
368	Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to ikbka deficiency	Enrichment	CHUK	1.59
369	Atypical timothy syndrome	Enrichment	CACNA1C	1.59
370	Aldosterone-producing adenoma with seizures and neurological abnormalities	Enrichment	CACNA1D	1.59
371	Menke-hennekam syndrome	Enrichment	CREBBP	1.59
372	Ganglioglioma	Enrichment	BRAF	1.59
373	Nongerminomatous germ cell tumor	Enrichment	BRAF	1.59
374	Monostotic fibrous dysplasia	Enrichment	GNAS	1.59
375	Monosomy 9q22.3	Enrichment	PTCH1	1.59
376	Phace syndrome	Enrichment	BRAF	1.59
377	Timothy syndrome type 2	Enrichment	CACNA1C	1.59
378	Gnao1-related disorder	Enrichment	GNAO1	1.59
379	Periodic paralysis with transient compartment-like syndrome	Enrichment	CACNA1S	1.59
380	Classic hairy cell leukemia	Enrichment	BRAF	1.59
381	Phakomatosis cesiomarmorata	Enrichment	GNA11	1.59
382	Malignant epithelial tumor of salivary glands	Enrichment	PRKD1	1.59
383	Kaposiform hemangioendothelioma	Enrichment	GNA14	1.59
384	Mazabraud syndrome	Enrichment	GNAS	1.59
385	Calf-predominant weakness-gastrocnemius medialis atrophy-distal myopathy	Enrichment	RYR1	1.59
386	Timothy syndrome type 1	Enrichment	CACNA1C	1.59
387	Distal 17p13.3 microdeletion syndrome	Enrichment	YWHAE	1.59
388	Inflammatory bowel disease-recurrent sinopulmonary infections syndrome	Enrichment	NFAT5	1.59
389	Cone dystrophy with supernormal rod response	Enrichment	KCNV2	1.59
390	Microcystic stromal tumor	Enrichment	CTNNB1	1.59
391	Cacna1c-related disorders	Enrichment	CACNA1C	1.59
392	Benign paroxysmal torticollis of infancy	Enrichment	CACNA1A	1.59
393	Benign samaritan congenital myopathy	Enrichment	RYR1	1.59
394	Stroke, ischemic	Enrichment	NOS3, PRKCH	1.59
395	Inflammatory bowel disease 1	Enrichment	IL6, PRKCQ	1.57
396	Ventricular septal defect	Enrichment	BRAF, TEK	1.57
397	Renal cell carcinoma, papillary, 1	Enrichment	MET, MTOR	1.53
398	Oligoarticular juvenile idiopathic arthritis	Enrichment	IL2RA, PTPN2	1.53
399	Overgrowth syndrome	Enrichment	MTOR, PIK3R1	1.53
400	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	IL2RA, PTPN2	1.53
401	Leukemia, acute myeloid	Enrichment	FLT3, KIT, KRAS, NRAS	1.53
402	Primary ovarian insufficiency	Enrichment	BMP6, KDR, NOS3, NTRK1, RYR3	1.53
403	Lymphatic malformation 5	Enrichment	EPHB4	1.53
404	Brachydactyly, type b1	Enrichment	ROR2	1.53
405	Erythroleukemia, familial	Enrichment	ERBB3	1.53
406	Hypochondroplasia	Enrichment	FGFR3	1.53
407	Beare-stevenson cutis gyrata syndrome	Enrichment	FGFR2	1.53
408	Paget disease, extramammary	Enrichment	ERBB2	1.53
409	Osteoglophonic dysplasia	Enrichment	FGFR1	1.53
410	Thanatophoric dysplasia, type i	Enrichment	FGFR3	1.53
411	Microspherophakia and/or megalocornea, with ectopia lentis and with or without secondary glaucoma	Enrichment	LTBP2	1.53
412	Trigonocephaly 1	Enrichment	FGFR1	1.53
413	Donohue syndrome	Enrichment	INSR	1.53
414	Spinocerebellar ataxia 27a	Enrichment	FGF14	1.53
415	Oculoectodermal syndrome	Enrichment	KRAS	1.53
416	Muenke syndrome	Enrichment	FGFR3	1.53
417	Premature aging syndrome, penttinen type	Enrichment	PDGFRB	1.53
418	Hyperinsulinemic hypoglycemia, familial, 5	Enrichment	INSR	1.53
419	Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities	Enrichment	INSR	1.53
420	Glaucoma 3, primary congenital, d	Enrichment	LTBP2	1.53
421	Diabetes mellitus, insulin-resistant, with acanthosis nigricans	Enrichment	INSR	1.53
422	Microphthalmia, isolated 4	Enrichment	GDF6	1.53
423	Angel-shaped phalangoepiphyseal dysplasia	Enrichment	GDF5	1.53
424	Hypereosinophilic syndrome, idiopathic	Enrichment	PDGFRA	1.53
425	Deafness, autosomal recessive 39	Enrichment	HGF	1.53
426	Mastocytosis, cutaneous	Enrichment	KIT	1.53
427	Scaphocephaly, maxillary retrusion, and impaired intellectual development	Enrichment	FGFR2	1.53
428	Resting heart rate, variation in	Enrichment	ADRB1	1.53
429	Apert syndrome	Enrichment	FGFR2	1.53
430	Neuroblastoma 3	Enrichment	ALK	1.53
431	Basal ganglia calcification, idiopathic, 5	Enrichment	PDGFB	1.53
432	Hyperpigmentation with or without hypopigmentation, familial progressive	Enrichment	KITLG	1.53
433	Myofibromatosis, infantile, 1	Enrichment	PDGFRB	1.53
434	Melanosis, neurocutaneous	Enrichment	NRAS	1.53
435	Thanatophoric dysplasia, type ii	Enrichment	FGFR3	1.53
436	Lethal congenital contracture syndrome 2	Enrichment	ERBB3	1.53
437	Noonan syndrome 6	Enrichment	NRAS	1.53
438	Hypogonadotropic hypogonadism 20 with or without anosmia	Enrichment	FGF17	1.53
439	Ciliary dyskinesia, primary, 33	Enrichment	DRC4	1.53
440	Gist-plus syndrome	Enrichment	PDGFRA	1.53
441	Camptodactyly, tall stature, and hearing loss syndrome	Enrichment	FGFR3	1.53
442	Hypogonadotropic hypogonadism 23 with or without anosmia	Enrichment	LHB	1.53
443	Aplasia of lacrimal and salivary glands	Enrichment	FGF10	1.53
444	Bent bone dysplasia syndrome 1	Enrichment	FGFR2	1.53
445	Weill-marchesani syndrome 3	Enrichment	LTBP2	1.53
446	Noonan syndrome 11	Enrichment	MRAS	1.53
447	Visceral neuropathy, familial, 2, autosomal recessive	Enrichment	ERBB2	1.53
448	Deafness, autosomal recessive 108	Enrichment	ROR1	1.53
449	Myasthenic syndrome, congenital, 9, associated with acetylcholine receptor deficiency	Enrichment	MUSK	1.53
450	Developmental and epileptic encephalopathy 58	Enrichment	NTRK2	1.53
451	Multiple synostoses syndrome 4	Enrichment	GDF6	1.53
452	Intellectual developmental disorder, x-linked 110	Enrichment	FGF13	1.53
453	Joubert syndrome 32	Enrichment	SUFU	1.53
454	Spinocerebellar ataxia 27b, late-onset	Enrichment	FGF14	1.53
455	Venous malformations, multiple cutaneous and mucosal	Enrichment	TEK	1.53
456	Hyperemesis gravidarum	Enrichment	GDF15	1.53
457	Amegakaryocytic thrombocytopenia, congenital, 2	Enrichment	THPO	1.53
458	Deafness, autosomal recessive 125	Enrichment	GAS2	1.53
459	Hereditary lymphedema id	Enrichment	VEGFC	1.53
460	Osteofibrous dysplasia	Enrichment	MET	1.53
461	Microphthalmia, syndromic 6	Enrichment	BMP4	1.53
462	Spondylometaepiphyseal dysplasia, short limb-hand type	Enrichment	DDR2	1.53
463	Myeloid and lymphoid neoplasms associated with pdgfra rearrangement	Enrichment	PDGFRA	1.53
464	Developmental and epileptic encephalopathy 90	Enrichment	FGF13	1.53
465	Orofacial cleft 11	Enrichment	BMP4	1.53
466	Metacarpal 4-5 fusion	Enrichment	FGF16	1.53
467	Lymphatic malformation 4	Enrichment	VEGFC	1.53
468	Ferguson-bonni neurodevelopmental syndrome	Enrichment	ANAPC7	1.53
469	Lacrimoauriculodentodigital syndrome 3	Enrichment	FGF10	1.53
470	Familial isolated trichomegaly	Enrichment	FGF5	1.53
471	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	1.53
472	Deafness, autosomal recessive 97	Enrichment	MET	1.53
473	Prostate cancer/brain cancer susceptibility	Enrichment	EPHB2	1.53
474	Skin/hair/eye pigmentation, variation in, 7	Enrichment	KITLG	1.53
475	Crouzon syndrome with acanthosis nigricans	Enrichment	FGFR3	1.53
476	Geleophysic dysplasia 3	Enrichment	LTBP3	1.53
477	Rothmund-thomson syndrome, type 1	Enrichment	ANAPC1	1.53
478	Autism 9	Enrichment	MET	1.53
479	Glaucoma 1, open angle, o	Enrichment	NTF4	1.53
480	Iron overload	Enrichment	BMP6	1.53
481	Basal ganglia calcification, idiopathic, 4	Enrichment	PDGFRB	1.53
482	Hypogonadotropic hypogonadism 12 with or without anosmia	Enrichment	GNRH1	1.53
483	Hypogonadotropic hypogonadism 16 with or without anosmia	Enrichment	SEMA3A	1.53
484	Leber congenital amaurosis 17	Enrichment	GDF6	1.53
485	Telangiectasia, hereditary hemorrhagic, type 5	Enrichment	GDF2	1.53
486	Amyotrophic lateral sclerosis 19	Enrichment	ERBB4	1.53
487	Hereditary thrombocytosis with transverse limb defect	Enrichment	THPO	1.53
488	Nasopharyngeal carcinoma 3	Enrichment	MST1R	1.53
489	Myeloid and lymphoid neoplasms associated with pdgfrb rearrangement	Enrichment	PDGFRB	1.53
490	Acute myeloid leukemia with minimal differentiation	Enrichment	FLT3	1.53
491	Hypogonadotropic hypogonadism 6 with or without anosmia	Enrichment	FGF8	1.53
492	Obesity, hyperphagia, and developmental delay	Enrichment	NTRK2	1.53
493	Achondroplasia, severe, with developmental delay and acanthosis nigricans	Enrichment	FGFR3	1.53
494	Kosaki overgrowth syndrome	Enrichment	PDGFRB	1.53
495	Tumoral calcinosis, hyperphosphatemic, familial, 2	Enrichment	FGF23	1.53
496	Hartsfield syndrome	Enrichment	FGFR1	1.53
497	Congenital heart defects, multiple types, 7	Enrichment	FLT4	1.53
498	Renal hypodysplasia/aplasia 2	Enrichment	FGF20	1.53
499	Bleeding disorder, platelet-type, 22	Enrichment	EPHB2	1.53
500	20p12.3 microdeletion syndrome	Enrichment	BMP2	1.53
501	Mahvash disease	Enrichment	GCGR	1.53
502	Thrombocytopenia 6	Enrichment	SRC	1.53
503	Cutis laxa, autosomal recessive, type iie	Enrichment	LTBP1	1.53
504	Glaucoma 3, primary congenital, e	Enrichment	TEK	1.53
505	Short stature, facial dysmorphism, and skeletal anomalies with or without cardiac anomalies 1	Enrichment	BMP2	1.53
506	Brain abnormalities, neurodegeneration, and dysosteosclerosis	Enrichment	CSF1R	1.53
507	Short sleep, familial natural, 2	Enrichment	ADRB1	1.53
508	Developmental and epileptic encephalopathy 47	Enrichment	FGF12	1.53
509	Ocular pterygium-digital keloid dysplasia syndrome	Enrichment	PDGFRB	1.53
510	Chronic mast cell leukemia	Enrichment	KIT	1.53
511	Premature ovarian failure 14	Enrichment	GDF9	1.53
512	Ciliary dyskinesia, primary, 46	Enrichment	STK36	1.53
513	Warburg-cinotti syndrome	Enrichment	DDR2	1.53
514	Tufted angioma of skin	Enrichment	KDR	1.53
515	Deafness, autosomal dominant 69	Enrichment	KITLG	1.53
516	Thrombocytopenia 9	Enrichment	THPO	1.53
517	Arthrogryposis, distal, type 11	Enrichment	MET	1.53
518	Lacrimoauriculodentodigital syndrome 2	Enrichment	FGFR3	1.53
519	Csf1r-related disorder	Enrichment	CSF1R	1.53
520	Short-rib thoracic dysplasia 22 without polydactyly	Enrichment	FGF4	1.53
521	Lipodystrophy, familial partial, type 8	Enrichment	ADRA2A	1.53
522	Bockenheimer syndrome	Enrichment	TEK	1.53
523	Glaucoma secondary to spherophakia/ectopia lentis and megalocornea	Enrichment	LTBP2	1.53
524	Isolated bone marrow mastocytosis	Enrichment	KIT	1.53
525	Congenital pulmonary airway malformation	Enrichment	KRAS	1.53
526	Smoldering systemic mastocytosis	Enrichment	KIT	1.53
527	Alk-positive anaplastic large cell lymphoma	Enrichment	ALK	1.53
528	Spinocerebellar ataxia type 27b	Enrichment	FGF14	1.53
529	Fgfr3-related chondrodysplasia	Enrichment	FGFR3	1.53
530	Mastocytosis	Enrichment	KIT	1.53
531	Congenital primary lymphedema of gordon	Enrichment	VEGFC	1.53
532	Camptodactyly-tall stature-scoliosis-hearing loss syndrome	Enrichment	FGFR3	1.53
533	Familial progressive hyperpigmentation	Enrichment	KITLG	1.53
534	Early-onset calcifying leukoencephalopathy-skeletal dysplasia	Enrichment	CSF1R	1.53
535	Cutaneous mastocytoma	Enrichment	KIT	1.53
536	Typical urticaria pigmentosa	Enrichment	KIT	1.53
537	Phakomatosis pigmentokeratotica	Enrichment	HRAS	1.53
538	Nodular urticaria pigmentosa	Enrichment	KIT	1.53
539	Hartsfield-bixler-demyer syndrome	Enrichment	FGFR1	1.53
540	Alk-positive large b-cell lymphoma	Enrichment	ALK	1.53
541	Pseudoxanthomatous diffuse cutaneous mastocytosis	Enrichment	KIT	1.53
542	Telangiectasia macularis eruptiva perstans	Enrichment	KIT	1.53
543	Acute mast cell leukemia	Enrichment	KIT	1.53
544	Non-syndromic unicoronal craniosynostosis	Enrichment	FGFR2	1.53
545	Familial progressive hyper- and hypopigmentation	Enrichment	KITLG	1.53
546	Plaque-form urticaria pigmentosa	Enrichment	KIT	1.53
547	Interstitial lung disease specific to childhood	Enrichment	FGF10	1.53
548	Serous carcinoma of the corpus uteri	Enrichment	ERBB2	1.53
549	Ephb4-related lymphatic-related hydrops fetalis	Enrichment	EPHB4	1.53
550	Neurocutaneous melanocytosis	Enrichment	NRAS	1.53
551	Bullous diffuse cutaneous mastocytosis	Enrichment	KIT	1.53
552	Vein of galen aneurysmal malformation	Enrichment	EPHB4	1.53
553	Testis seminoma	Enrichment	KIT	1.53
554	Migraine with or without aura 1	Enrichment	CACNA1A, CLCN1	1.51
555	Epilepsy, myoclonic juvenile	Enrichment	CACNB4, CLCN2	1.51
556	Specific learning disability	Enrichment	MAPK1, YWHAG	1.51
557	Type 2 diabetes mellitus	Enrichment	IL6, INSR, PPP1R3A, PTPN1	1.47
558	Body mass index quantitative trait locus 11	Enrichment	ADCY3, ADRB3, BDNF, GNAS, SCN1A	1.44
559	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	RYR2, TGFB3	1.43
560	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	RYR2, TGFB3	1.43
561	Congenital long qt syndrome	Enrichment	ITPR3, SCN5A	1.43
562	Hypomagnesemia 4, renal	Enrichment	EGF	1.43
563	Noonan syndrome 4	Enrichment	SOS1	1.43
564	Noonan syndrome 9	Enrichment	SOS2	1.43
565	Intellectual developmental disorder, autosomal recessive 63	Enrichment	CAMK2A	1.43
566	Intellectual developmental disorder, autosomal dominant 54	Enrichment	CAMK2B	1.43
567	Intellectual developmental disorder, autosomal dominant 53	Enrichment	CAMK2A	1.43
568	Intellectual developmental disorder, autosomal dominant 59	Enrichment	CAMK2G	1.43
569	Idiopathic hypercalciuria	Enrichment	ADCY10	1.43
570	Egf-related primary hypomagnesemia with intellectual disability	Enrichment	EGF	1.43
571	Tetralogy of fallot	Enrichment	EPHB4, FLT4, KDR	1.40
572	Hydrops fetalis, nonimmune	Enrichment	EPHB4, FLT4, HRAS	1.40
573	Meningioma, familial	Enrichment	PDGFB, SUFU	1.40
574	Leukemia, acute lymphoblastic	Enrichment	FLT3, GNB1	1.40
575	Proteus syndrome	Enrichment	AKT1	1.40
576	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	1.40
577	Type 1 diabetes mellitus 10	Enrichment	IL2RA	1.40
578	Osteopetrosis and infantile neuroaxonal dystrophy	Enrichment	PLA2G6	1.40
579	Fleck retina, familial benign	Enrichment	PLA2G5	1.40
580	Ataxia-oculomotor apraxia 3	Enrichment	PIK3R5	1.40
581	Neurodegeneration with brain iron accumulation 2a	Enrichment	PLA2G6	1.40
582	Short syndrome	Enrichment	PIK3R1	1.40
583	Prolonged electroretinal response suppression 1	Enrichment	RGS9	1.40
584	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Enrichment	AKT3	1.40
585	Parkinson disease 14, autosomal recessive	Enrichment	PLA2G6	1.40
586	Neurodegeneration with brain iron accumulation 2b	Enrichment	PLA2G6	1.40
587	Cytosolic phospholipase-a2 alpha deficiency associated bleeding disorder	Enrichment	PLA2G4A	1.40
588	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	1.40
589	Cowden syndrome 6	Enrichment	AKT1	1.40
590	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	1.40
591	Platelet-activating factor acetylhydrolase deficiency	Enrichment	PLA2G7	1.40
592	Gastrointestinal ulceration, recurrent, with dysfunctional platelets	Enrichment	PLA2G4A	1.40
593	Gaze palsy, familial horizontal, with progressive scoliosis 2, with impaired intellectual development	Enrichment	DCC	1.40
594	Capillary hemangioma	Enrichment	AKT3	1.40
595	Cryptogenic multifocal ulcerous stenosing enteritis	Enrichment	PLA2G4A	1.40
596	Familial benign flecked retina	Enrichment	PLA2G5	1.40
597	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	1.40
598	Inherited cancer-predisposing syndrome	Enrichment	ALK, EGFR, KIT, MET, PDGFRA, PRKAR1A, PTCH1, SUFU	1.39
599	Renal hypodysplasia/aplasia 3	Enrichment	BMP4, FGFR3	1.33
600	Spastic ataxia	Enrichment	CACNA1G, CACNB4, ITPR1, SCN2A	1.33
601	Familial isolated dilated cardiomyopathy	Enrichment	PLN, RAF1, SCN5A, TNNI3	1.33
602	Aortic aneurysm, familial thoracic 1	Enrichment	MYLK, SMAD3	1.31
603	Heart disease	Enrichment	CREBBP, MYL2	1.31
604	Spinocerebellar ataxia 29	Enrichment	ITPR1	1.29
605	Malignant hyperthermia 1	Enrichment	RYR1	1.29
606	Atrial standstill 1	Enrichment	SCN5A	1.29
607	Progressive familial heart block, type ia	Enrichment	SCN5A	1.29
608	Paramyotonia congenita	Enrichment	SCN4A	1.29
609	Cardiomyopathy, familial restrictive, 1	Enrichment	TNNI3	1.29
610	Pseudohypoparathyroidism, type ia	Enrichment	GNAS	1.29
611	Myhre syndrome	Enrichment	SMAD4	1.29
612	Ventricular arrhythmias due to cardiac ryanodine receptor calcium release deficiency syndrome	Enrichment	RYR2	1.29
613	Camurati-engelmann disease 1	Enrichment	TGFB1	1.29
614	Pallister-hall-like syndrome	Enrichment	SMO	1.29
615	Amelogenesis imperfecta, type ig	Enrichment	PRKAR1A	1.29
616	Pituitary adenoma 4, acth-secreting	Enrichment	GNAI2	1.29
617	Glycogen storage disease 0, liver	Enrichment	GYS2	1.29
618	Cutis marmorata telangiectatica congenita	Enrichment	GNA11	1.29
619	Thumb deformity	Enrichment	CREBBP	1.29
620	Indifference to pain, congenital, autosomal recessive	Enrichment	SCN9A	1.29
621	Glycogen storage disease ixa1	Enrichment	PHKA2	1.29
622	Dent disease 1	Enrichment	CLCN5	1.29
623	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	1.29
624	Polymyoclonus, infantile	Enrichment	SCNN1B	1.29
625	Timothy syndrome	Enrichment	CACNA1C	1.29
626	Night blindness, congenital stationary, type 2a	Enrichment	CACNA1F	1.29
627	Hyperaldosteronism, familial, type ii	Enrichment	CLCN2	1.29
628	Osteopetrosis, autosomal recessive 4	Enrichment	CLCN7	1.29
629	Nephrolithiasis, x-linked recessive, with renal failure	Enrichment	CLCN5	1.29
630	46,xy gonadal dysgenesis with minifascicular neuropathy	Enrichment	DHH	1.29
631	Vitamin d hydroxylation-deficient rickets, type 1b	Enrichment	PDE3B	1.29
632	Histiocytoma, angiomatoid fibrous	Enrichment	CREB1	1.29
633	Alternating hemiplegia of childhood 1	Enrichment	CACNA1A	1.29
634	Pseudopseudohypoparathyroidism	Enrichment	GNAS	1.29
635	Seizures, benign familial infantile, 3	Enrichment	SCN2A	1.29
636	Sick sinus syndrome 1	Enrichment	SCN5A	1.29
637	Ectodermal dysplasia and immunodeficiency 2	Enrichment	NFKBIA	1.29
638	Myotonia, potassium-aggravated	Enrichment	SCN4A	1.29
639	Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome	Enrichment	SMAD4	1.29
640	Microvascular complications of diabetes 5	Enrichment	TGFBR2	1.29
641	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	1.29
642	Cardiomyopathy, dilated, 1p	Enrichment	PLN	1.29
643	Segawa syndrome, autosomal recessive	Enrichment	TH	1.29
644	Birk-barel syndrome	Enrichment	KCNK9	1.29
645	Lethal congenital contracture syndrome 8	Enrichment	ADCY6	1.29
646	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	1.29
647	Cardiomyopathy, familial hypertrophic, 25	Enrichment	TNNI3	1.29
648	Atrial fibrillation, familial, 10	Enrichment	SCN5A	1.29
649	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	1.29
650	Spermatogenic failure 17	Enrichment	PLCZ1	1.29
651	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	1.29
652	Migraine, familial hemiplegic, 3	Enrichment	SCN1A	1.29
653	Cardiomyopathy, familial hypertrophic, 18	Enrichment	PLN	1.29
654	Cognitive impairment with or without cerebellar ataxia	Enrichment	SCN8A	1.29
655	Cardiomyopathy, dilated, 1ff	Enrichment	TNNI3	1.29
656	Long qt syndrome 14	Enrichment	CALM1	1.29
657	Oguchi disease 2	Enrichment	GRK1	1.29
658	Loeys-dietz syndrome 3	Enrichment	SMAD3	1.29
659	Epilepsy, nocturnal frontal lobe, 5	Enrichment	KCNT1	1.29
660	Leukoencephalopathy with ataxia	Enrichment	CLCN2	1.29
661	Long qt syndrome 3	Enrichment	SCN5A	1.29
662	Developmental and epileptic encephalopathy 15	Enrichment	KCNT1	1.29
663	Long qt syndrome 8	Enrichment	CACNA1C	1.29
664	Developmental and epileptic encephalopathy 6b	Enrichment	SCN1A	1.29
665	Sinoatrial node disease	Enrichment	SCN5A	1.29
666	Genitourinary and/or brain malformation syndrome	Enrichment	PPP1R12A	1.29
667	Marbach-schaaf neurodevelopmental syndrome	Enrichment	PRKAR1B	1.29
668	Osteogenesis imperfecta, type xxi	Enrichment	KDELR2	1.29
669	Hypophosphatemic rickets, x-linked recessive	Enrichment	CLCN5	1.29
670	Dystonia 30	Enrichment	PTPRA	1.29
671	Facial dysmorphism, hypertrichosis, epilepsy, intellectual/developmental delay, and gingival overgrowth syndrome	Enrichment	KCNK4	1.29
672	Congenital myopathy 22a, classic	Enrichment	SCN4A	1.29
673	Congenital myopathy 22b, severe fetal	Enrichment	SCN4A	1.29
674	Usher syndrome, type iv	Enrichment	PRKAR1A	1.29
675	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.29
676	Proteinuria, low molecular weight, with hypercalciuria and nephrocalcinosis	Enrichment	CLCN5	1.29
677	Retinitis pigmentosa 49	Enrichment	CNGA1	1.29
678	Myasthenic syndrome, congenital, 16	Enrichment	SCN4A	1.29
679	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	1.29
680	Glycogen storage disease 0, muscle	Enrichment	GYS1	1.29
681	Ventricular tachycardia, catecholaminergic polymorphic, 2	Enrichment	RYR2	1.29
682	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	1.29
683	Autosomal dominant hypocalcemia	Enrichment	GNA11	1.29
684	Cardiomyopathy, familial hypertrophic, 10	Enrichment	MYL2	1.29
685	King-denborough syndrome	Enrichment	RYR1	1.29
686	Acrodysostosis	Enrichment	PRKAR1A	1.29
687	Benign familial neonatal epilepsy	Enrichment	SCN2A	1.29
688	Pseudohypoparathyroidism	Enrichment	GNAS	1.29
689	Camurati-engelmann disease	Enrichment	TGFB1	1.29
690	Developmental and epileptic encephalopathy 30	Enrichment	SCN2A	1.29
691	Body mass index quantitative trait locus 19	Enrichment	ADCY3	1.29
692	Neurogenic bladder	Enrichment	CLCN6	1.29
693	Immunodeficiency 104, severe combined	Enrichment	PTPRC	1.29
694	Respiratory system disease	Enrichment	CLCN6	1.29
695	Fibrolamellar carcinoma	Enrichment	PRKACA	1.29
696	Ocular melanoma	Enrichment	PLCB4	1.29
697	Ectodermal dysplasia and immune deficiency	Enrichment	NFKBIA	1.29
698	Ciliary dyskinesia, primary, 18	Enrichment	PRKAR1B	1.29
699	Myopathy, myofibrillar, 12, infantile-onset, with cardiomyopathy	Enrichment	MYL2	1.29
700	Hypopituitarism	Enrichment	GNAI2	1.29
701	Congenital disorder of glycosylation, type iw, autosomal dominant	Enrichment	CACNA1D	1.29
702	Epilepsy, progressive myoclonic, 3, with or without intracellular inclusions	Enrichment	KCTD7	1.29
703	Hypokalemic periodic paralysis, type 2	Enrichment	SCN4A	1.29
704	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	1.29
705	Scn1a seizure disorders	Enrichment	SCN1A	1.29
706	Seizures, benign familial infantile, 5	Enrichment	SCN8A	1.29
707	Neurodevelopmental disorder with seizures and nonepileptic hyperkinetic movements	Enrichment	CACNA1B	1.29
708	Arthrogryposis, distal, type 1c	Enrichment	MYL11	1.29
709	Megacystis-microcolon-intestinal hypoperistalsis syndrome 4	Enrichment	MYL9	1.29
710	Glycogen storage disorder due to hepatic glycogen synthase deficiency	Enrichment	GYS2	1.29
711	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.29
712	Exercise-induced malignant hyperthermia	Enrichment	RYR1	1.29
713	Developmental and epileptic encephalopathy 76	Enrichment	SCN1A	1.29
714	Isolated primary pigmented nodular adrenocortical disease	Enrichment	PRKAR1A	1.29
715	Joint contractures, osteochondromas, and b-cell lymphoma	Enrichment	NFATC2	1.29
716	Clcn2-related leukoencephalopathy	Enrichment	CLCN2	1.29
717	Postaxial polydactyly type b	Enrichment	GLI1	1.29
718	Acth-independent macronodular adrenal hyperplasia	Enrichment	GNAS	1.29
719	Glycogen storage disease due to muscle and heart glycogen synthase deficiency	Enrichment	GYS1	1.29
720	Small fiber neuropathy	Enrichment	SCN9A	1.29
721	Benign neonatal seizures	Enrichment	SCN2A	1.29
722	Isolated atrial standstill	Enrichment	SCN5A	1.29
723	Oguchi disease	Enrichment	GRK1	1.29
724	Glycogen storage disease viii	Enrichment	PHKA2	1.29
725	Teratoma	Enrichment	CTNNB1	1.29
726	Osteosclerosis	Enrichment	CLCN7	1.29
727	Common variable immunodeficiency 12	Enrichment	NFKB1	1.29
728	Commissural facial cleft	Enrichment	PTCH2	1.29
729	Pseudohypoaldosteronism	Enrichment	SCNN1A	1.29
730	Tafro syndrome	Enrichment	MAP2K2	1.29
731	Progressive bulbar palsy	Enrichment	CACNA1A	1.29
732	Cerebral visual impairment	Enrichment	GNB1	1.29
733	Phakomatosis cesioflammea	Enrichment	GNA11	1.29
734	Polydactyly, postaxial, type a1	Enrichment	GLI1, PTCH1	1.26
735	Congenital myopathy 4a, autosomal dominant	Enrichment	MYL2, RYR1	1.26
736	Congenital nervous system abnormality	Enrichment	CACNA1A, CREBBP, CTNNB1, GNAO1, GNB5, KCNV2	1.25
737	Nervous system disease	Enrichment	CACNA1A, CREBBP, CTNNB1, GNAO1, GNB5, KCNV2	1.25
738	Acromicric dysplasia	Enrichment	LTBP3	1.24
739	Cri-du-chat syndrome	Enrichment	SEMA5A	1.24
740	Blue rubber bleb nevus	Enrichment	TEK	1.24
741	Sorsby fundus dystrophy	Enrichment	TIMP3	1.24
742	Myeloproliferative disorder, chronic, with eosinophilia	Enrichment	PDGFRB	1.24
743	Costello syndrome	Enrichment	HRAS	1.24
744	Insensitivity to pain, congenital, with anhidrosis	Enrichment	NTRK1	1.24
745	Trichomegaly	Enrichment	FGF5	1.24
746	Visceral neuropathy, familial, 1, autosomal recessive	Enrichment	ERBB3	1.24
747	Kyphomelic dysplasia	Enrichment	CCN2	1.24
748	Omodysplasia 1	Enrichment	GPC6	1.24
749	Pulmonary hypoplasia, primary	Enrichment	FGF10	1.24
750	Dermatofibrosarcoma protuberans	Enrichment	PDGFB	1.24
751	Cervical cancer	Enrichment	FGFR3	1.24
752	Parkinson disease 8, autosomal dominant	Enrichment	GDF6	1.24
753	Piebald trait	Enrichment	KIT	1.24
754	Hyperinsulinemic hypoglycemia, familial, 4	Enrichment	INSR	1.24
755	Aural atresia, congenital	Enrichment	FGFR2	1.24
756	Keratosis, seborrheic	Enrichment	FGFR3	1.24
757	Multiple synostoses syndrome 2	Enrichment	GDF5	1.24
758	Myopathy, mitochondrial progressive, with congenital cataract and developmental delay	Enrichment	GFER	1.24
759	Cutis laxa, autosomal recessive, type ic	Enrichment	LTBP4	1.24
760	Silver-russell syndrome 3	Enrichment	IGF2	1.24
761	Osteogenesis imperfecta, type xiii	Enrichment	BMP1	1.24
762	Brachydactyly, type a1, c	Enrichment	GDF5	1.24
763	Symphalangism, proximal, 1b	Enrichment	GDF5	1.24
764	Pain sensitivity quantitative trait locus 1	Enrichment	NTRK1	1.24
765	Antley-bixler syndrome without genital anomalies or disordered steroidogenesis	Enrichment	FGFR2	1.24
766	Spondyloepimetaphyseal dysplasia, li-shao-li type	Enrichment	CCN2	1.24
767	Waardenburg syndrome, type 2f	Enrichment	KITLG	1.24
768	Lymphatic malformation 11	Enrichment	TIE1	1.24
769	Noonan syndrome 12	Enrichment	RRAS2	1.24
770	Kowarski syndrome	Enrichment	GH1	1.24
771	Infantile myofibromatosis	Enrichment	PDGFRB	1.24
772	Split hand-foot malformation	Enrichment	FGFR2	1.24
773	Rosette-forming glioneuronal tumor	Enrichment	FGFR1	1.24
774	Papillary renal cell carcinoma	Enrichment	MET	1.24
775	Congenital mesoblastic nephroma	Enrichment	NTRK3	1.24
776	Congenital fibrosarcoma	Enrichment	SUFU	1.24
777	Microphthalmia/coloboma 6	Enrichment	GDF6	1.24
778	Cervix carcinoma	Enrichment	FGFR3	1.24
779	Fibrosarcoma	Enrichment	NTRK3	1.24
780	Retinitis pigmentosa 38	Enrichment	MERTK	1.24
781	Proximal symphalangism	Enrichment	GDF5	1.24
782	Craniosynostosis 7	Enrichment	BMP2	1.24
783	Acute myeloid leukemia without maturation	Enrichment	FLT3	1.24
784	Congenital amegakaryocytic thrombocytopenia	Enrichment	THPO	1.24
785	Interfrontal craniofaciosynostosis	Enrichment	FGFR1	1.24
786	Basal cell nevus syndrome 2	Enrichment	SUFU	1.24
787	Short stature due to growth hormone qualitative anomaly	Enrichment	GH1	1.24
788	Autosomal dominant nonsyndromic deafness	Enrichment	FGFR2	1.24
789	Chronic eosinophilic leukemia	Enrichment	PDGFRA	1.24
790	Growth delay due to insulin-like growth factor type 1 deficiency	Enrichment	IGF1	1.24
791	B-lymphoblastic leukemia/lymphoma with recurrent genetic abnormality	Enrichment	PDGFRA	1.24
792	Mixed phenotype acute leukemia with t(9;22)(q34.1;q11.2)	Enrichment	FLT3	1.24
793	B-lymphoblastic leukemia/lymphoma with t	Enrichment	KIT	1.24
794	Silver-russell syndrome due to an imprinting defect of 11p15	Enrichment	IGF2	1.24
795	Wooly hair nevus	Enrichment	HRAS	1.24
796	Silver-russell syndrome due to 11p15 microduplication	Enrichment	IGF2	1.24
797	Polymicrogyria	Enrichment	AKT3, SCN3A	1.24
798	Heritable pulmonary arterial hypertension	Enrichment	GDF2, KCNK3	1.22
799	Dystonia	Enrichment	GNAL, GNB1, TH	1.22
800	Cleft lip/palate	Enrichment	BMP4, PDGFRA	1.21
801	Cardiomyopathy, dilated, 1e	Enrichment	MYL2, SCN5A	1.16
802	Postsynaptic congenital myasthenic syndromes	Enrichment	MUSK, SCN4A	1.15
803	Wilms tumor 1	Enrichment	BRAF, IGF2	1.15
804	Hydrocephalus	Enrichment	FGFR2, PDGFRB	1.15
805	Fibromatosis, gingival, 1	Enrichment	SOS1	1.14
806	Hypercalciuria, absorptive, 2	Enrichment	ADCY10	1.14
807	Bartter syndrome, type 3	Enrichment	CLCNKB	1.14
808	Desmoid disease, hereditary	Enrichment	CTNNB1	1.12
809	Mccune-albright syndrome	Enrichment	GNAS	1.12
810	Dystonia 12	Enrichment	SCN2A	1.12
811	Van der woude syndrome 1	Enrichment	CACNA1E	1.12
812	Dystonia, dopa-responsive	Enrichment	TH	1.12
813	Myotonia congenita, autosomal dominant	Enrichment	CLCN1	1.12
814	Ataxia-telangiectasia	Enrichment	BRAF	1.12
815	Juvenile polyposis syndrome	Enrichment	SMAD4	1.12
816	Myotonia congenita, autosomal recessive	Enrichment	CLCN1	1.12
817	Gillespie syndrome	Enrichment	ITPR1	1.12
818	Glycogen storage disease ixb	Enrichment	PHKB	1.12
819	Vitamin d hydroxylation-deficient rickets, type 1a	Enrichment	PDE3B	1.12
820	Epilepsy, nocturnal frontal lobe, 1	Enrichment	KCNT1	1.12
821	Nasopharyngeal carcinoma	Enrichment	NFKBIA	1.12
822	Nephrotic syndrome, type 3	Enrichment	PLCE1	1.12
823	Generalized epilepsy with febrile seizures plus, type 2	Enrichment	SCN1A	1.12
824	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.12
825	Aortic aneurysm, familial thoracic 7	Enrichment	MYLK	1.12
826	Holoprosencephaly 7	Enrichment	PTCH1	1.12
827	Lipodystrophy, familial partial, type 6	Enrichment	LIPE	1.12
828	Developmental and epileptic encephalopathy 13	Enrichment	SCN8A	1.12
829	Miller-dieker lissencephaly syndrome	Enrichment	YWHAE	1.12
830	Generalized epilepsy with febrile seizures plus, type 7	Enrichment	SCN9A	1.12
831	Chromosome 17p13.3, centromeric, duplication syndrome	Enrichment	YWHAE	1.12
832	Lynch syndrome 5	Enrichment	RYR1	1.12
833	Anus, imperforate	Enrichment	CTNNB1	1.12
834	Tremor, hereditary essential, 6	Enrichment	SCN4A	1.12
835	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.12
836	Dent disease	Enrichment	CLCN5	1.12
837	Desmoid tumor	Enrichment	CTNNB1	1.12
838	Osteopetrosis, autosomal recessive 6	Enrichment	CLCN7	1.12
839	Intrinsic cardiomyopathy	Enrichment	PLN	1.12
840	Ciliary dyskinesia, primary, 28	Enrichment	KCNT1	1.12
841	Gingival overgrowth	Enrichment	KCNK4	1.12
842	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	1.12
843	Cushing syndrome due to bilateral macronodular adrenocortical disease	Enrichment	GNAS	1.12
844	Thyrotoxic periodic paralysis	Enrichment	CACNA1S	1.12
845	Hypomyelination neuropathy-arthrogryposis syndrome	Enrichment	ADCY6	1.12
846	Scoliosis, isolated 1	Enrichment	MAPK7	1.11
847	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	PIK3R5	1.11
848	Immunodeficiency 41 with lymphoproliferation and autoimmunity	Enrichment	IL2RA	1.11
849	Cebalid syndrome	Enrichment	MTOR	1.11
850	Senior-loken syndrome 7	Enrichment	AKT3	1.11
851	Bardet-biedl syndrome 16	Enrichment	AKT3	1.11
852	Bradyopsia	Enrichment	RGS9	1.11
853	Smith-kingsmore syndrome	Enrichment	MTOR	1.11
854	Horizontal gaze palsy with progressive scoliosis	Enrichment	DCC	1.11
855	Infantile osteopetrosis with neuroaxonal dysplasia	Enrichment	PLA2G6	1.11
856	Pulmonary hypertension, primary, 1	Enrichment	GDF2, KCNK3	1.09
857	Myopathy	Enrichment	CLCN1, RYR1, SCN4A	1.08
858	Diffuse large b-cell lymphoma	Enrichment	BRAF, CREBBP	1.07
859	Achondroplasia	Enrichment	FGFR3	1.07
860	Brachydactyly, type c	Enrichment	GDF5	1.07
861	Hypogonadotropic hypogonadism 2 with or without anosmia	Enrichment	FGFR1	1.07
862	Larsen syndrome	Enrichment	FGFR3	1.07
863	Klippel-feil syndrome 1, autosomal dominant	Enrichment	GDF6	1.07
864	Thyroid carcinoma, familial medullary	Enrichment	NTRK1	1.07
865	Exfoliation syndrome	Enrichment	LTBP2	1.07
866	Tumoral calcinosis, hyperphosphatemic, familial, 1	Enrichment	FGF23	1.07
867	Acromesomelic dysplasia 2a	Enrichment	GDF5	1.07
868	Thrombocythemia 1	Enrichment	THPO	1.07
869	Hypophosphatemic rickets, autosomal dominant	Enrichment	FGF23	1.07
870	Acromesomelic dysplasia 2c	Enrichment	GDF5	1.07
871	Acromesomelic dysplasia 2b	Enrichment	GDF5	1.07
872	Leukoencephalopathy, hereditary diffuse, with spheroids 1	Enrichment	CSF1R	1.07
873	Stuve-wiedemann syndrome 1	Enrichment	LIFR	1.07
874	Muscular dystrophy, duchenne type	Enrichment	LTBP4	1.07
875	Transposition of the great arteries, dextro-looped	Enrichment	BMP2	1.07
876	Chromosome 8p11 myeloproliferative syndrome	Enrichment	FGFR1	1.07
877	Dyskeratosis congenita, autosomal dominant 6	Enrichment	THPO	1.07
878	Neonatal nephrocutaneous inflammatory syndrome	Enrichment	EGFR	1.07
879	Weill-marchesani syndrome 1	Enrichment	LTBP2	1.07
880	Primary polycythemia	Enrichment	EPOR	1.07
881	Autosomal recessive cutis laxa type i	Enrichment	LTBP1	1.07
882	Isolated growth hormone deficiency, type ib	Enrichment	GH1	1.07
883	Hamartoma	Enrichment	FGFR3	1.07
884	Lymphatic malformation 7	Enrichment	EPHB4	1.07
885	Capillary malformation-arteriovenous malformation 2	Enrichment	EPHB4	1.07
886	Desmoplastic/nodular medulloblastoma	Enrichment	SUFU	1.07
887	Growth delay due to insulin-like growth factor i resistance	Enrichment	IGF1R	1.07
888	High bone mass osteogenesis imperfecta	Enrichment	BMP1	1.07
889	Neonatal inflammatory skin and bowel disease	Enrichment	EGFR	1.07
890	Mixed phenotype acute leukemia with t	Enrichment	FLT3	1.07
891	Geleophysic dysplasia	Enrichment	LTBP3	1.07
892	Renal cell carcinoma	Enrichment	MET	1.07
893	Stüve-wiedemann syndrome	Enrichment	LIFR	1.07
894	Testicular cancer	Enrichment	FGFR3	1.07
895	Isolated klippel-feil syndrome	Enrichment	GDF6	1.07
896	Beckwith-wiedemann syndrome due to imprinting defect of 11p15	Enrichment	IGF2	1.07
897	Mpv17-related mitochondrial dna maintenance defect	Enrichment	UCN	1.07
898	Alzheimer disease, familial, 1	Enrichment	CSF1R, NOS3	1.06
899	Dandy-walker syndrome	Enrichment	BRAF, PDGFRB	1.06
900	Beckwith-wiedemann syndrome	Enrichment	IGF2, RYR1	1.01
901	Microcephaly	Enrichment	CTNNB1, GNAO1, GNB1, MAPK1, SCN1A, YWHAG	1.01
902	Migraine, familial hemiplegic, 1	Enrichment	CACNA1A	1.00
903	Chorea, benign hereditary	Enrichment	ADCY5	1.00
904	Congenital myopathy 1a, autosomal dominant, with malignant hyperthermia	Enrichment	RYR1	1.00
905	Polydactyly, preaxial ii	Enrichment	PTCH1	1.00
906	Megacystis-microcolon-intestinal hypoperistalsis syndrome 1	Enrichment	MYLK	1.00
907	Spinocerebellar ataxia 6	Enrichment	CACNA1A	1.00
908	Neuropathy, hereditary sensory and autonomic, type iia	Enrichment	SCN9A	1.00
909	Spastic paraplegia 17, autosomal dominant	Enrichment	GNG3	1.00
910	Myopathy, centronuclear, 2	Enrichment	RYR1	1.00
911	Sacral defect with anterior meningocele	Enrichment	RYR1	1.00
912	Thyroid cancer, nonmedullary, 1	Enrichment	BRAF	1.00
913	Pseudohypoparathyroidism, type ib	Enrichment	GNAS	1.00
914	Hypophosphatemic rickets, x-linked dominant	Enrichment	CLCN5	1.00
915	Amyotrophy, monomelic	Enrichment	RYR3	1.00
916	Developmental and epileptic encephalopathy 2	Enrichment	CACNA1A	1.00
917	Smith-lemli-opitz syndrome	Enrichment	CLCN1	1.00
918	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	1.00
919	Lipodystrophy, congenital generalized, type 2	Enrichment	GNG3	1.00
920	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	1.00
921	Pilomatrixoma	Enrichment	CTNNB1	1.00
922	Carney complex variant	Enrichment	PRKAR1A	1.00
923	Spinocerebellar ataxia 15	Enrichment	ITPR1	1.00
924	Arrhythmogenic right ventricular dysplasia, familial, 10	Enrichment	PRKAR1A	1.00
925	Long qt syndrome 2	Enrichment	SCN5A	1.00
926	Developmental and epileptic encephalopathy 42	Enrichment	CACNA1A	1.00
927	Alazami syndrome	Enrichment	CTNNB1	1.00
928	Intellectual developmental disorder, autosomal dominant 26	Enrichment	RYR1	1.00
929	Cerebellar atrophy with seizures and variable developmental delay	Enrichment	CACNA2D2	1.00
930	Hereditary sensory and autonomic neuropathy type 2	Enrichment	SCN9A	1.00
931	Atrial fibrillation	Enrichment	SCN5A	1.00
932	Hereditary ataxia	Enrichment	PRKCG	1.00
933	Color blindness	Enrichment	CNGA3	1.00
934	Congenital myopathy 1a	Enrichment	RYR1	1.00
935	Sotos syndrome 1	Enrichment	SCN4A	1.00
936	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	YWHAZ	1.00
937	Spastic quadriplegic cerebral palsy	Enrichment	ADD3	1.00
938	Newborn respiratory distress syndrome	Enrichment	BRAF	1.00
939	Autosomal recessive osteopetrosis	Enrichment	CLCN7	1.00
940	Sick sinus syndrome	Enrichment	SCN5A	1.00
941	Cardiomyopathy, dilated, 1a	Enrichment	NFATC2, TNNI3	1.00
942	Centronuclear myopathy	Enrichment	CACNA1S, RYR1	1.00
943	Optic atrophy plus syndrome	Enrichment	CACNA1F, CNGA3, CNGB3	0.99
944	Osteopetrosis, autosomal dominant 1	Enrichment	CLCNKB	0.97
945	Nuchal bleb, familial	Enrichment	SOS1	0.97
946	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	ADCY1, CLCNKA, CLIC5, HGF, MET, ROR1	0.95
947	Kaposi sarcoma	Enrichment	IL6	0.95
948	Isolated growth hormone deficiency, type ii	Enrichment	GH1	0.95
949	Erythrocytosis, familial, 1	Enrichment	EPOR	0.95
950	Diffuse gastric and lobular breast cancer syndrome	Enrichment	KRAS	0.95
951	Mitochondrial dna depletion syndrome 6	Enrichment	UCN	0.95
952	Microtia-anotia	Enrichment	BMP5	0.95
953	Barrett esophagus	Enrichment	ERBB2	0.95
954	Charcot-marie-tooth disease, axonal, type 2ee	Enrichment	UCN	0.95
955	Lung sarcomatoid carcinoma	Enrichment	KRAS	0.95
956	Weill-marchesani syndrome	Enrichment	LTBP2	0.95
957	Chronic myelomonocytic leukemia	Enrichment	FLT3	0.95
958	Pilocytic astrocytoma	Enrichment	KRAS	0.95
959	Epidermolytic nevus	Enrichment	HRAS	0.95
960	Silver-russell syndrome due to a point mutation	Enrichment	IGF2	0.95
961	Non-syndromic bicoronal craniosynostosis	Enrichment	FGFR3	0.95
962	Systemic mastocytosis with associated hematologic neoplasm	Enrichment	KIT	0.95
963	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	0.95
964	Oculomotor apraxia	Enrichment	SUFU	0.95
965	Autism	Enrichment	CREBBP, SCN1A, SCN2A, SCN8A	0.94
966	Late-onset retinal degeneration	Enrichment	PLA2G5	0.94
967	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	0.94
968	Immunodeficiency 14	Enrichment	PIK3R1	0.94
969	Macs syndrome	Enrichment	GDF6, PTCH1	0.94
970	Craniosynostosis	Enrichment	FGFR2, FGFR3	0.94
971	Renal cell carcinoma, nonpapillary	Enrichment	MET, MTOR	0.93
972	Corpus callosum, agenesis of	Enrichment	CREBBP, DCC	0.93
973	Isolated corpus callosum agenesis	Enrichment	CREBBP, DCC	0.93
974	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP, DCC	0.93
975	Capillary malformations, congenital	Enrichment	GNA11	0.91
976	Alzheimer disease 2	Enrichment	NOS3	0.91
977	Sotos syndrome	Enrichment	SCN4A	0.91
978	Episodic ataxia, type 2	Enrichment	CACNA1A	0.91
979	Arrhythmogenic right ventricular dysplasia, familial, 1	Enrichment	TGFB3	0.91
980	Visceral myopathy 1	Enrichment	MYLK	0.91
981	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	0.91
982	Congenital myopathy 1b, autosomal recessive	Enrichment	RYR1	0.91
983	Arthrogryposis, distal, type 2b1	Enrichment	TNNI2	0.91
984	Night blindness, congenital stationary, type 1c	Enrichment	GNAT1	0.91
985	Amblyopia	Enrichment	CACNA1F	0.91
986	Osteopetrosis	Enrichment	CLCN7	0.91
987	Arrhythmogenic right ventricular dysplasia 1	Enrichment	TGFB3	0.91
988	Macular degeneration	Enrichment	CNGA3	0.91
989	Congenital short qt syndrome	Enrichment	CACNA2D1	0.91
990	Endometrial stromal sarcoma	Enrichment	YWHAE	0.91
991	Sensory peripheral neuropathy	Enrichment	SCN11A	0.91
992	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	SMAD4	0.91
993	Scoliosis	Enrichment	CREBBP, RYR1	0.90
994	Gastric cancer	Enrichment	ERBB2, FGFR2, KRAS	0.88
995	Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay	Enrichment	KCTD3, PLA2G6	0.88
996	Tooth agenesis	Enrichment	FGFR1, TGFA	0.87
997	Cataract 6, multiple types	Enrichment	EPHA2	0.86
998	Robinow syndrome, autosomal recessive 1	Enrichment	ROR2	0.86
999	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	0.86
1000	Atrioventricular septal defect	Enrichment	BMP5	0.86
1001	Congenital heart defects, multiple types, 4	Enrichment	BMP7	0.86
1002	Juvenile glaucoma	Enrichment	LTBP2	0.86
1003	Aniridia	Enrichment	EPHA2	0.86
1004	Diffuse cutaneous systemic sclerosis	Enrichment	CCN2	0.86
1005	Gingival fibromatosis	Enrichment	SOS1	0.85
1006	Male infertility due to gonadal dysgenesis or sperm disorder	Enrichment	SOS2	0.85
1007	Auditory neuropathy	Enrichment	CACNA1A, H1-4	0.84
1008	Myopathy, centronuclear, 1	Enrichment	RYR1	0.84
1009	Weyers acrofacial dysostosis	Enrichment	CTNNB1	0.84
1010	Rubinstein-taybi syndrome 1	Enrichment	CREBBP	0.84
1011	Metachromatic leukodystrophy	Enrichment	CLCN1	0.84
1012	Wilms tumor 5	Enrichment	BRAF	0.84
1013	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP	0.84
1014	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	0.84
1015	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1	0.84
1016	Pain disorder	Enrichment	SCN4A	0.84
1017	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	0.84
1018	Hypertrichosis	Enrichment	CREBBP	0.84
1019	Classic ehlers-danlos syndrome	Enrichment	TGFBR1	0.84
1020	Kidney clear cell sarcoma	Enrichment	YWHAE	0.84
1021	Childhood absence epilepsy	Enrichment	CACNA1H	0.84
1022	Focal cortical dysplasia, type ii	Enrichment	MTOR	0.82
1023	Adenosine deaminase deficiency	Enrichment	PKIG	0.82
1024	Isolated focal cortical dysplasia type ii	Enrichment	MTOR	0.82
1025	Strabismus	Enrichment	CACNA1A, GNB1	0.82
1026	Glaucoma, primary open angle	Enrichment	LTBP2	0.79
1027	Cowden syndrome 1	Enrichment	EGFR	0.79
1028	Split-hand/foot malformation 1	Enrichment	FGFR2	0.79
1029	Wilms tumor, aniridia, genitourinary anomalies, and impaired intellectual development syndrome	Enrichment	BDNF	0.79
1030	Type 1 diabetes mellitus	Enrichment	IL6	0.79
1031	Dental anomalies and short stature	Enrichment	LTBP3	0.79
1032	Anterior segment dysgenesis 5	Enrichment	BMP4	0.79
1033	Mitochondrial dna depletion syndrome 1	Enrichment	TYMP	0.79
1034	Inflammatory myofibroblastic tumor	Enrichment	ALK	0.79
1035	Familial adult myoclonic epilepsy	Enrichment	ADRA2B	0.79
1036	Autosomal recessive robinow syndrome	Enrichment	ROR2	0.79
1037	Limited scleroderma	Enrichment	CCN2	0.79
1038	Esophageal cancer	Enrichment	TGFBR2	0.78
1039	Polymicrogyria, bilateral perisylvian, x-linked	Enrichment	SCN3A	0.78
1040	Brachydactyly	Enrichment	GNAS	0.78
1041	Hereditary hemorrhagic telangiectasia	Enrichment	SMAD4	0.78
1042	Common variable immunodeficiency	Enrichment	NFKB1	0.78
1043	Autosomal dominant sleep-related hypermotor epilepsy	Enrichment	KCNT1	0.78
1044	Paroxysmal dystonia	Enrichment	PDE2A	0.78
1045	Congenital hydrocephalus	Enrichment	PTCH1	0.78
1046	Gitelman syndrome	Enrichment	CLCNKB	0.77
1047	Breast cancer	Enrichment	GNG3, IL2, KRAS, PTCH2	0.75
1048	Stargardt disease 1	Enrichment	CNGB3, KCNV2	0.74
1049	Spastic paraplegia 4, autosomal dominant	Enrichment	GNAS	0.73
1050	Spermatogenic failure 5	Enrichment	AKAP3	0.73
1051	Multiple pterygium syndrome, lethal type	Enrichment	RYR1	0.73
1052	Lymphoma, non-hodgkin, familial	Enrichment	BRAF	0.73
1053	Exudative vitreoretinopathy	Enrichment	CTNNB1	0.73
1054	Congenital muscular dystrophy	Enrichment	RYR1	0.73
1055	Hypothyroidism	Enrichment	GNB1	0.73
1056	Myocarditis	Enrichment	TNNI3	0.73
1057	Difference of sex development	Enrichment	CACNA1A	0.73
1058	Silver-russell syndrome 1	Enrichment	IGF2	0.72
1059	Myelofibrosis	Enrichment	SRC	0.72
1060	Squamous cell carcinoma, head and neck	Enrichment	EGFR	0.72
1061	Waardenburg syndrome, type 2e	Enrichment	KITLG	0.72
1062	Essential thrombocythemia	Enrichment	THPO	0.72
1063	Hypophosphatemic rickets	Enrichment	FGF23	0.72
1064	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	FLT3	0.72
1065	Cystic fibrosis	Enrichment	CLCA4, TGFB1	0.70
1066	Connective tissue disease	Enrichment	SMAD3, TGFBR2	0.70
1067	Tracheoesophageal fistula with or without esophageal atresia	Enrichment	ADD1	0.68
1068	Bronchiectasis with or without elevated sweat chloride 1	Enrichment	SCNN1B	0.68
1069	Nephrotic syndrome, type 1	Enrichment	PLCE1	0.68
1070	Arrhythmogenic right ventricular dysplasia, familial, 9	Enrichment	PLN	0.68
1071	Myoclonic-atonic epilepsy	Enrichment	SCN1A	0.68
1072	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	CACNA1C	0.68
1073	Adult hepatocellular carcinoma	Enrichment	CTNNB1	0.68
1074	Bilateral perisylvian polymicrogyria	Enrichment	SCN3A	0.68
1075	Familial isolated arrhythmogenic right ventricular dysplasia	Enrichment	SCN5A	0.68
1076	Isolated growth hormone deficiency, type ia	Enrichment	GH1	0.67
1077	Mitochondrial dna depletion syndrome 4b	Enrichment	TYMP	0.67
1078	Neuroblastoma	Enrichment	ALK	0.67
1079	Early-onset posterior polar cataract	Enrichment	EPHA2	0.67
1080	Hereditary retinal dystrophy	Enrichment	CACNA1F, CACNA2D4, CNGA1, CNGA3, CNGB1, CNGB3, GNAT1, GNAT2, GRK1, KCNV2	0.67
1081	Fundus dystrophy	Enrichment	CACNA1F, CACNA2D4, CNGA1, CNGA3, CNGB1, CNGB3, GNAT1, GNAT2, GRK1, KCNV2	0.67
1082	Complex neurodevelopmental disorder	Enrichment	CACNA1C, CLCN3, GNB2, SCN2A, SCN8A	0.67
1083	Hepatocellular carcinoma	Enrichment	IGF2R, MET	0.66
1084	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	0.64
1085	Melanoma	Enrichment	BRAF	0.64
1086	Progressive myoclonus epilepsy	Enrichment	KCTD7	0.64
1087	Isolated tracheo-esophageal fistula	Enrichment	ADD1	0.64
1088	Epilepsy, familial focal, with variable foci 1	Enrichment	CLCNKB	0.64
1089	Bartter disease	Enrichment	CLCNKB	0.64
1090	Orofacial cleft 1	Enrichment	FGF10	0.63
1091	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	FLT3	0.63
1092	Hypogonadotropic hypogonadism	Enrichment	FGFR1	0.63
1093	Congenital central hypoventilation syndrome	Enrichment	BDNF	0.63
1094	Mitochondrial neurogastrointestinal encephalomyopathy	Enrichment	TYMP	0.63
1095	Renal agenesis, bilateral	Enrichment	FGF20	0.63
1096	Megacolon	Enrichment	AKT3	0.60
1097	Pectus excavatum	Enrichment	TGFBR1	0.60
1098	Epilepsy, idiopathic generalized	Enrichment	CACNA1H	0.60
1099	Myelodysplastic syndrome	Enrichment	GNB1	0.60
1100	46,xy complete gonadal dysgenesis	Enrichment	DHH	0.60
1101	Meier-gorlin syndrome 1	Enrichment	FGFR2	0.59
1102	Peters-plus syndrome	Enrichment	BMP4	0.59
1103	Myasthenic syndrome, congenital, 4c, associated with acetylcholine receptor deficiency	Enrichment	MUSK	0.59
1104	Stickler syndrome	Enrichment	BMP4	0.59
1105	Primary bone dysplasia	Enrichment	FGFR3	0.59
1106	Cakut	Enrichment	GDF6, LIFR	0.58
1107	Restrictive cardiomyopathy	Enrichment	TNNI3	0.57
1108	Frontotemporal dementia 1	Enrichment	CSF1R	0.55
1109	Osteochondrodysplasia	Enrichment	FGFR3	0.55
1110	Clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly	Enrichment	RYR1	0.54
1111	Pulmonary disease, chronic obstructive	Enrichment	PDE3B	0.54
1112	Acute promyelocytic leukemia	Enrichment	PRKAR1A	0.54
1113	Clubfoot	Enrichment	RYR1	0.54
1114	Septooptic dysplasia	Enrichment	FGFR1	0.52
1115	Cutis laxa	Enrichment	LTBP4	0.52
1116	Nephrotic syndrome	Enrichment	CLCN5, PLCE1	0.52
1117	Multiple sclerosis	Enrichment	ITPR1	0.51
1118	Myoclonic epilepsy of unverricht and lundborg	Enrichment	KCTD7	0.51
1119	Cowden syndrome	Enrichment	AKT1	0.51
1120	Alzheimer's disease	Enrichment	CSF1R	0.49
1121	Oligospermia	Enrichment	CDK16	0.49
1122	Amelogenesis imperfecta	Enrichment	LTBP3	0.49
1123	Protein-deficiency anemia	Enrichment	NRAS	0.49
1124	Myopia	Enrichment	CACNA1F	0.49
1125	Anterior segment dysgenesis	Enrichment	ITPR1	0.49
1126	Neuronal ceroid lipofuscinosis	Enrichment	KCTD7	0.49
1127	Lynch syndrome	Enrichment	TGFBR2	0.49
1128	Neurodegeneration with brain iron accumulation	Enrichment	PLA2G6	0.48
1129	Familial colorectal cancer	Enrichment	PLA2G2A	0.48
1130	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3R1	0.48
1131	Wolff-parkinson-white syndrome	Enrichment	SCN5A	0.47
1132	Hypogonadotropic hypogonadism 7 with or without anosmia	Enrichment	FGFR1	0.47
1133	Osteoporosis	Enrichment	SRC	0.47
1134	Cataract	Enrichment	EPHA2	0.47
1135	Melanoma, cutaneous malignant 1	Enrichment	BRAF	0.45
1136	Cleft palate, isolated	Enrichment	GNB1	0.45
1137	Polycystic liver disease	Enrichment	CTNNB1	0.45
1138	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	0.45
1139	Osteogenesis imperfecta, type iii	Enrichment	BMP1	0.44
1140	Heart, malformation of	Enrichment	MAPK1	0.43
1141	Neuromuscular disease	Enrichment	RYR1	0.43
1142	Severe combined immunodeficiency	Enrichment	PKIG, PTPRC	0.42
1143	Aortic valve disease 1	Enrichment	SOS1	0.41
1144	Primary ciliary dyskinesia	Enrichment	DRC4, PRKAR1B, STK36	0.41
1145	Esophageal atresia/tracheoesophageal fistula	Enrichment	ADD1	0.41
1146	Cataract 44	Enrichment	EPHA2	0.40
1147	Focal segmental glomerulosclerosis	Enrichment	PLCE1	0.39
1148	46,xy partial gonadal dysgenesis	Enrichment	SOS1	0.39
1149	Thrombocytopenia	Enrichment	SRC, THPO	0.38
1150	Human immunodeficiency virus type 1	Enrichment	CXCL12	0.38
1151	Early-onset nuclear cataract	Enrichment	EPHA2	0.38
1152	Hepatoblastoma	Enrichment	CTNNB1	0.37
1153	Attention deficit-hyperactivity disorder	Enrichment	GNB5	0.36
1154	Myocardial infarction	Enrichment	CLCN1	0.36
1155	Visceral heterotaxy	Enrichment	LEFTY2	0.36
1156	Microphthalmia	Enrichment	PTCH1	0.36
1157	Skin disease	Enrichment	CLCN6	0.36
1158	Malaria	Enrichment	SCN8A	0.35
1159	Non-syndromic male infertility due to sperm motility disorder	Enrichment	AKAP4	0.35
1160	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	KITLG, PDE1C	0.34
1161	Retinitis pigmentosa	Enrichment	CACNA1F, CACNA2D4, CNGA1, CNGB1, CNGB3, GNAT1	0.33
1162	Endometrial cancer	Enrichment	FGFR2	0.33
1163	Pancreatic cancer	Enrichment	SMAD4	0.32
1164	Hereditary breast ovarian cancer syndrome	Enrichment	KRAS, PTCH1	0.32
1165	Brittle bone disorder	Enrichment	BMP1	0.30
1166	Precursor t-cell acute lymphoblastic leukemia	Enrichment	FLT3	0.30
1167	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	CSF1R, ERBB4	0.29
1168	Hereditary breast carcinoma	Enrichment	AKT1, KRAS	0.28
1169	Sensorineural hearing loss	Enrichment	CLCNKA, HGF	0.27
1170	Autism spectrum disorder	Enrichment	GNB1, MAP2K1, SCN2A	0.27
1171	Prostate cancer	Enrichment	EPHB2	0.24
1172	Genetic steroid-resistant nephrotic syndrome	Enrichment	PLCE1	0.23
1173	Isolated joubert syndrome	Enrichment	SUFU	0.23
1174	Non-syndromic x-linked intellectual disability	Enrichment	CLCN4	0.22
1175	Peripheral nervous system disease	Enrichment	NGF	0.21
1176	Neuropathy	Enrichment	NGF	0.21
1177	Deafness, autosomal recessive	Enrichment	CLCNKA, CLIC5	0.17
1178	Autosomal recessive nonsyndromic deafness	Enrichment	CLCNKA, CLIC5	0.16
1179	Leber plus disease	Enrichment	CNGB3, GDF6, RGS9	0.13
1180	Hypertelorism	Enrichment	FGFR2	0.10
1181	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	FGF8	0.09
1182	Mitochondrial disease	Enrichment	GFER	0.03

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Activation of cAMP-Dependent PKA

Pathway Network for Activation of cAMP-Dependent PKA

Pathway network for the Activation of cAMP-Dependent PKA SuperPath

Member Pathways for Activation of cAMP-Dependent PKA

Pathways in the Activation of cAMP-Dependent PKA SuperPath

Gene overlap in member pathways for Activation of cAMP-Dependent PKA SuperPath

Associated Genes for Activation of cAMP-Dependent PKA

Associated Disorders for Activation of cAMP-Dependent PKA

Disorders associated with Activation of cAMP-Dependent PKA SuperPath

STRING Interaction Network for Activation of cAMP-Dependent PKA

Sources for Activation of cAMP-Dependent PKA