Adhesion

No Pathway Network information available for Adhesion

Pathways in the Adhesion SuperPath

#	Name	Source	Genes
1	Adhesion	Cell Signaling Technology	ADAM10 ADAM9 ADAMTS1 AFDN AGR2 AJUBA AMOT ARHGEF6 ARHGEF7 ATP1B1 BCAR1 BSG CAV1 CCN1 CCN2 CCN3 CD151 CD44 CD63 CDCP1 CDH1 CDH11 CDH17 CDH2 CDH3 CDH4 CDH5 CDH6 CEACAM1 CEACAM5 CLDN1 CLDN3 COL1A1 CTNNA1 CTNNA2 CTNNB1 CTNND1 CXADR DDR2 DIXDC1 DOCK1 DSP EPCAM F3 FERMT1 FERMT2 FERMT3 GIT1 GIT2 GJA1 GPNMB IBSP ICAM1 ICAM2 ILK ITGA4 ITGA5 ITGA6 ITGAV ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 JUP KLK3 LAMC1 LIMS1 LPXN MCAM MMP13 MMP14 MMP2 MMP3 MMP9 MPZL1 MSLN MTDH MUC1 NCAM1 NECTIN4 NEDD9 NEO1 OLFM4 PANX1 PARVA PDCD6IP PLAUR PLEC PLG PPFIBP1 PTK2 PTPN12 PTPN14 PTPRA PTPRF PVR PXN RAP1A RAP1B REG4 SCRIB SDC1 SDC4 SERPINE1 SH3PXD2A SIRPA SLK SRCIN1 ST14 TACSTD2 TFCP2 TFF1 TGFB1I1 TGFBI TJP1 TJP2 TJP3 TLN1 TNS2 VCAM1 VCL ZYX (see all 123) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ADAM10	ADAM Metallopeptidase Domain 10	Protein Coding	1
2	ADAM9	ADAM Metallopeptidase Domain 9	Protein Coding	1
3	ADAMTS1	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 1	Protein Coding	1
4	AFDN	Afadin, Adherens Junction Formation Factor	Protein Coding	1
5	AGR2	Anterior Gradient 2, Protein Disulphide Isomerase Family Member	Protein Coding	1
6	PDCD6IP	Programmed Cell Death 6 Interacting Protein	Protein Coding	1
7	AMOT	Angiomotin	Protein Coding	1
8	ARHGEF6	Rac/Cdc42 Guanine Nucleotide Exchange Factor 6	Protein Coding	1
9	ARHGEF7	Rho Guanine Nucleotide Exchange Factor 7	Protein Coding	1
10	ATP1B1	ATPase Na+/K+ Transporting Subunit Beta 1	Protein Coding	1
11	TGFBI	Transforming Growth Factor Beta Induced	Protein Coding	1
12	BSG	Basigin (Ok Blood Group)	Protein Coding	1
13	NEDD9	Neural Precursor Cell Expressed, Developmentally Down-Regulated 9	Protein Coding	1
14	CAV1	Caveolin 1	Protein Coding	1
15	CD151	CD151 Molecule (Raph Blood Group)	Protein Coding	1
16	CD44	CD44 Molecule (IN Blood Group)	Protein Coding	1
17	CD63	CD63 Molecule	Protein Coding	1
18	CDCP1	CUB Domain Containing Protein 1	Protein Coding	1
19	CDH1	Cadherin 1	Protein Coding	1
20	CDH11	Cadherin 11	Protein Coding	1
21	CDH17	Cadherin 17	Protein Coding	1
22	CDH2	Cadherin 2	Protein Coding	1
23	CDH3	Cadherin 3	Protein Coding	1
24	CDH4	Cadherin 4	Protein Coding	1
25	CDH5	Cadherin 5	Protein Coding	1
26	CDH6	Cadherin 6	Protein Coding	1
27	CEACAM1	CEA Cell Adhesion Molecule 1	Protein Coding	1
28	CEACAM5	CEA Cell Adhesion Molecule 5	Protein Coding	1
29	CLDN1	Claudin 1	Protein Coding	1
30	CLDN3	Claudin 3	Protein Coding	1
31	COL1A1	Collagen Type I Alpha 1 Chain	Protein Coding	1
32	CCN2	Cellular Communication Network Factor 2	Protein Coding	1
33	CTNNA1	Catenin Alpha 1	Protein Coding	1
34	CTNNA2	Catenin Alpha 2	Protein Coding	1
35	CTNNB1	Catenin Beta 1	Protein Coding	1
36	CTNND1	Catenin Delta 1	Protein Coding	1
37	JUP	Junction Plakoglobin	Protein Coding	1
38	CXADR	CXADR Cell Adhesion Molecule	Protein Coding	1
39	CCN1	Cellular Communication Network Factor 1	Protein Coding	1
40	DDR2	Discoidin Domain Receptor Tyrosine Kinase 2	Protein Coding	1
41	DSP	Desmoplakin	Protein Coding	1
42	DIXDC1	DIX Domain Containing 1	Protein Coding	1
43	DOCK1	Dedicator Of Cytokinesis 1	Protein Coding	1
44	EPCAM	Epithelial Cell Adhesion Molecule	Protein Coding	1
45	F3	Coagulation Factor III, Tissue Factor	Protein Coding	1
46	PTK2	Protein Tyrosine Kinase 2	Protein Coding	1
47	GIT1	GIT ArfGAP 1	Protein Coding	1
48	GIT2	GIT ArfGAP 2	Protein Coding	1
49	GJA1	Gap Junction Protein Alpha 1	Protein Coding	1
50	GPNMB	Glycoprotein Nmb	Protein Coding	1
51	TGFB1I1	Transforming Growth Factor Beta 1 Induced Transcript 1	Protein Coding	1
52	ICAM1	Intercellular Adhesion Molecule 1	Protein Coding	1
53	ICAM2	Intercellular Adhesion Molecule 2	Protein Coding	1
54	ILK	Integrin Linked Kinase	Protein Coding	1
55	ITGA4	Integrin Subunit Alpha 4	Protein Coding	1
56	ITGA5	Integrin Subunit Alpha 5	Protein Coding	1
57	ITGA6	Integrin Subunit Alpha 6	Protein Coding	1
58	ITGAV	Integrin Subunit Alpha V	Protein Coding	1
59	ITGB1	Integrin Subunit Beta 1	Protein Coding	1
60	ITGB2	Integrin Subunit Beta 2	Protein Coding	1
61	ITGB3	Integrin Subunit Beta 3	Protein Coding	1
62	ITGB4	Integrin Subunit Beta 4	Protein Coding	1
63	ITGB5	Integrin Subunit Beta 5	Protein Coding	1
64	AJUBA	Ajuba LIM Protein	Protein Coding	1
65	FERMT1	FERM Domain Containing Kindlin 1	Protein Coding	1
66	FERMT2	FERM Domain Containing Kindlin 2	Protein Coding	1
67	FERMT3	FERM Domain Containing Kindlin 3	Protein Coding	1
68	LAMC1	Laminin Subunit Gamma 1	Protein Coding	1
69	LPXN	Leupaxin	Protein Coding	1
70	LIMS1	LIM Zinc Finger Domain Containing 1	Protein Coding	1
71	PPFIBP1	PPFIB Scaffold Protein 1	Protein Coding	1
72	MTDH	Metadherin	Protein Coding	1
73	MCAM	Melanoma Cell Adhesion Molecule	Protein Coding	1
74	MMP13	Matrix Metallopeptidase 13	Protein Coding	1
75	MMP14	Matrix Metallopeptidase 14	Protein Coding	1
76	MMP2	Matrix Metallopeptidase 2	Protein Coding	1
77	MMP3	Matrix Metallopeptidase 3	Protein Coding	1
78	MMP9	Matrix Metallopeptidase 9	Protein Coding	1
79	MSLN	Mesothelin	Protein Coding	1
80	MUC1	Mucin 1, Cell Surface Associated	Protein Coding	1
81	NCAM1	Neural Cell Adhesion Molecule 1	Protein Coding	1
82	NECTIN4	Nectin Cell Adhesion Molecule 4	Protein Coding	1
83	NEO1	Neogenin 1	Protein Coding	1
84	CCN3	Cellular Communication Network Factor 3	Protein Coding	1
85	OLFM4	Olfactomedin 4	Protein Coding	1
86	BCAR1	BCAR1 Scaffold Protein, Cas Family Member	Protein Coding	1
87	PANX1	Pannexin 1	Protein Coding	1
88	PARVA	Parvin Alpha	Protein Coding	1
89	PLG	Plasminogen	Protein Coding	1
90	PLEC	Plectin	Protein Coding	1
91	KLK3	Kallikrein Related Peptidase 3	Protein Coding	1
92	PTPN12	Protein Tyrosine Phosphatase Non-Receptor Type 12	Protein Coding	1
93	PTPN14	Protein Tyrosine Phosphatase Non-Receptor Type 14	Protein Coding	1
94	PTPRA	Protein Tyrosine Phosphatase Receptor Type A	Protein Coding	1
95	PTPRF	Protein Tyrosine Phosphatase Receptor Type F	Protein Coding	1
96	PVR	PVR Cell Adhesion Molecule	Protein Coding	1
97	PXN	Paxillin	Protein Coding	1
98	MPZL1	Myelin Protein Zero Like 1	Protein Coding	1
99	RAP1A	RAP1A, Member Of RAS Oncogene Family	Protein Coding	1
100	RAP1B	RAP1B, Member Of RAS Oncogene Family	Protein Coding	1
101	REG4	Regenerating Family Member 4	Protein Coding	1
102	SCRIB	Scribble Planar Cell Polarity Protein	Protein Coding	1
103	SERPINE1	Serpin Family E Member 1	Protein Coding	1
104	SIRPA	Signal Regulatory Protein Alpha	Protein Coding	1
105	IBSP	Integrin Binding Sialoprotein	Protein Coding	1
106	SLK	STE20 Like Kinase	Protein Coding	1
107	SRCIN1	SRC Kinase Signaling Inhibitor 1	Protein Coding	1
108	ST14	ST14 Transmembrane Serine Protease Matriptase	Protein Coding	1
109	SDC1	Syndecan 1	Protein Coding	1
110	SDC4	Syndecan 4	Protein Coding	1
111	TACSTD2	Tumor Associated Calcium Signal Transducer 2	Protein Coding	1
112	TLN1	Talin 1	Protein Coding	1
113	TNS2	Tensin 2	Protein Coding	1
114	TFCP2	Transcription Factor CP2	Protein Coding	1
115	TFF1	Trefoil Factor 1	Protein Coding	1
116	SH3PXD2A	SH3 And PX Domains 2A	Protein Coding	1
117	PLAUR	Plasminogen Activator, Urokinase Receptor	Protein Coding	1
118	VCAM1	Vascular Cell Adhesion Molecule 1	Protein Coding	1
119	VCL	Vinculin	Protein Coding	1
120	TJP1	Tight Junction Protein 1	Protein Coding	1
121	TJP2	Tight Junction Protein 2	Protein Coding	1
122	TJP3	Tight Junction Protein 3	Protein Coding	1
123	ZYX	Zyxin	Protein Coding	1

Disorders associated with Adhesion SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	ITGA6, ITGB4, PLEC	4.85
2	Blepharocheilodontic syndrome 1	Enrichment	CDH1, CTNND1	4.09
3	Leukocyte adhesion deficiency, type i	Enrichment	FERMT3, ITGB2	4.09
4	Leukocyte adhesion deficiency, type iii	Enrichment	FERMT3, ITGB2	4.09
5	Metaphyseal anadysplasia	Enrichment	MMP13, MMP9	4.09
6	Multicentric osteolysis, nodulosis, and arthropathy	Enrichment	MMP14, MMP2	3.61
7	Epidermolysis bullosa, lethal acantholytic	Enrichment	DSP, JUP	3.61
8	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	CDH2, DSP, JUP	3.61
9	Diffuse gastric and lobular breast cancer syndrome	Enrichment	CDH1, CTNNA1	3.32
10	Epidermolysis bullosa simplex 5c, with pyloric atresia	Enrichment	ITGB4, PLEC	3.32
11	Aplasia cutis congenita	Enrichment	ITGB4, PLEC	3.10
12	Diffuse cutaneous systemic sclerosis	Enrichment	CAV1, CCN2	3.10
13	Skin disease	Enrichment	FERMT1, ITGB4, PLEC	3.01
14	Colorectal cancer	Enrichment	CDH1, CTNNA1, CTNNB1, EPCAM, PTPN12	2.94
15	Limited scleroderma	Enrichment	CAV1, CCN2	2.92
16	Cleft lip with or without cleft palate	Enrichment	CDH1, CTNND1	2.92
17	Epidermolysis bullosa simplex	Enrichment	ITGB4, PLEC	2.78
18	Junctional epidermolysis bullosa	Enrichment	ITGA6, ITGB4	2.55
19	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	DSP, JUP	2.29
20	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	DSP, JUP	2.29
21	Neural tube defects	Enrichment	ITGB1, SCRIB	2.22
22	Multiple sclerosis	Enrichment	ITGB4, PLEC	2.16
23	Arrhythmogenic right ventricular cardiomyopathy	Enrichment	DSP, JUP	2.05
24	Palmoplantar keratoderma and congenital alopecia 1	Enrichment	GJA1	2.04
25	Corneal dystrophy, epithelial basement membrane	Enrichment	TGFBI	2.04
26	Kindler syndrome	Enrichment	FERMT1	2.04
27	Corneal dystrophy, groenouw type i	Enrichment	TGFBI	2.04
28	Ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome	Enrichment	CDH3	2.04
29	Elsahy-waters syndrome	Enrichment	CDH11	2.04
30	Hypoplastic left heart syndrome 1	Enrichment	GJA1	2.04
31	Ichthyosis, congenital, autosomal recessive 11	Enrichment	ST14	2.04
32	Corneal dystrophy, avellino type	Enrichment	TGFBI	2.04
33	Arrhythmogenic right ventricular dysplasia, familial, 12	Enrichment	JUP	2.04
34	Lipodystrophy, congenital generalized, type 3	Enrichment	CAV1	2.04
35	Macular dystrophy, patterned, 2	Enrichment	CTNNA1	2.04
36	Deafness, autosomal dominant 51	Enrichment	TJP2	2.04
37	Tubulointerstitial kidney disease, autosomal dominant 2	Enrichment	MUC1	2.04
38	Cone-rod dystrophy 9	Enrichment	ADAM9	2.04
39	Oculodentodigital dysplasia	Enrichment	GJA1	2.04
40	Raph blood group system	Enrichment	CD151	2.04
41	Breasts and/or nipples, aplasia or hypoplasia of, 1	Enrichment	PTPRF	2.04
42	Corneal dystrophy, lattice type i	Enrichment	TGFBI	2.04
43	Corneal dystrophy, gelatinous drop-like	Enrichment	TACSTD2	2.04
44	Pulmonary hypertension, primary, 3	Enrichment	CAV1	2.04
45	Craniometaphyseal dysplasia, autosomal recessive	Enrichment	GJA1	2.04
46	Naxos disease	Enrichment	JUP	2.04
47	Angioedema, hereditary, 4	Enrichment	PLG	2.04
48	Corneal dystrophy, thiel-behnke type	Enrichment	TGFBI	2.04
49	Teebi hypertelorism syndrome 2	Enrichment	CDH11	2.04
50	Breasts and/or nipples, aplasia or hypoplasia of, 2	Enrichment	PTPRF	2.04
51	Neurodevelopmental disorder with seizures, microcephaly, and brain abnormalities	Enrichment	PPFIBP1	2.04
52	Respiratory infections, recurrent, and failure to thrive with or without diarrhea	Enrichment	AGR2	2.04
53	Cortical dysplasia, complex, with other brain malformations 9	Enrichment	CTNNA2	2.04
54	Winchester syndrome	Enrichment	MMP14	2.04
55	Spondylometaepiphyseal dysplasia, short limb-hand type	Enrichment	DDR2	2.04
56	Intellectual developmental disorder, x-linked 46	Enrichment	ARHGEF6	2.04
57	Agenesis of corpus callosum, cardiac, ocular, and genital syndrome	Enrichment	CDH2	2.04
58	Epithelial-stromal tgfbi dystrophy	Enrichment	TGFBI	2.04
59	Plasminogen activator inhibitor-1 deficiency	Enrichment	SERPINE1	2.04
60	Oculodentodigital dysplasia, autosomal recessive	Enrichment	GJA1	2.04
61	Lipodystrophy, familial partial, type 7	Enrichment	CAV1	2.04
62	Alzheimer disease 18	Enrichment	ADAM10	2.04
63	Cardiomyopathy, dilated, 1w	Enrichment	VCL	2.04
64	Hypotrichosis	Enrichment	CDH3	2.04
65	Corneal dystrophy, lattice type iiia	Enrichment	TGFBI	2.04
66	Corneal dystrophy, reis-bucklers type	Enrichment	TGFBI	2.04
67	Epidermolysis bullosa simplex 7, with nephropathy and deafness	Enrichment	CD151	2.04
68	Arrhythmogenic right ventricular dysplasia, familial, 14	Enrichment	CDH2	2.04
69	Granular corneal dystrophy	Enrichment	TGFBI	2.04
70	Coronary heart disease 6	Enrichment	MMP3	2.04
71	Cardiomyopathy, familial hypertrophic, 15	Enrichment	VCL	2.04
72	Thrombocytopenia 11 with multiple congenital anomalies and dysmorphic facies	Enrichment	RAP1B	2.04
73	Reticulate acropigmentation of kitamura	Enrichment	ADAM10	2.04
74	Lynch syndrome 8	Enrichment	EPCAM	2.04
75	Ectodermal dysplasia-syndactyly syndrome 1	Enrichment	NECTIN4	2.04
76	Choanal atresia and lymphedema	Enrichment	PTPN14	2.04
77	Amyloidosis, primary localized cutaneous, 3	Enrichment	GPNMB	2.04
78	Erythrokeratodermia variabilis et progressiva 3	Enrichment	GJA1	2.04
79	Warburg-cinotti syndrome	Enrichment	DDR2	2.04
80	Asphyxia neonatorum	Enrichment	COL1A1	2.04
81	Microcephaly 29, primary, autosomal recessive	Enrichment	PDCD6IP	2.04
82	Attention deficit-hyperactivity disorder 8	Enrichment	CDH2	2.04
83	Adenoid ameloblastoma	Enrichment	CTNNB1	2.04
84	Epithelial basement membrane dystrophy	Enrichment	TGFBI	2.04
85	Skin fragility-woolly hair-palmoplantar keratoderma syndrome	Enrichment	DSP	2.04
86	Breast lobular carcinoma	Enrichment	CDH1	2.04
87	Immune dysregulation, neurodevelopmental defects, and colitis	Enrichment	ITGAV	2.04
88	Capillary leak syndrome	Enrichment	TLN1	2.04
89	Qualitative or quantitative defects of plectin	Enrichment	PLEC	2.04
90	Congenital plasminogen activator inhibitor type 1 deficiency	Enrichment	SERPINE1	2.04
91	Lymphedema-posterior choanal atresia syndrome	Enrichment	PTPN14	2.04
92	Microcystic stromal tumor	Enrichment	CTNNB1	2.04
93	Temporomandibular joint anomaly	Enrichment	DOCK1	2.04
94	Hereditary breast ovarian cancer syndrome	Enrichment	BCAR1, CTNNA1, CTNNA2	1.87
95	Epiphyseal dysplasia, multiple, 1	Enrichment	COL1A1	1.74
96	Epidermolysis bullosa simplex 5a, ogna type	Enrichment	PLEC	1.74
97	Epidermolysis bullosa simplex 5b, with muscular dystrophy	Enrichment	PLEC	1.74
98	Metaphyseal dysplasia, spahr type	Enrichment	MMP13	1.74
99	Plasminogen deficiency, type i	Enrichment	PLG	1.74
100	Kyphomelic dysplasia	Enrichment	CCN2	1.74
101	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	1.74
102	Spondyloepimetaphyseal dysplasia, missouri type	Enrichment	MMP13	1.74
103	Arrhythmogenic right ventricular dysplasia, familial, 8	Enrichment	DSP	1.74
104	Hypotrichosis, congenital, with juvenile macular dystrophy	Enrichment	CDH3	1.74
105	Dermatofibrosarcoma protuberans	Enrichment	COL1A1	1.74
106	Ichthyosis, leukocyte vacuoles, alopecia, and sclerosing cholangitis	Enrichment	CLDN1	1.74
107	Hallermann-streiff syndrome	Enrichment	GJA1	1.74
108	Cholestasis, progressive familial intrahepatic, 4	Enrichment	TJP2	1.74
109	Diarrhea 5, with tufting enteropathy, congenital	Enrichment	EPCAM	1.74
110	Muscular dystrophy, limb-girdle, autosomal recessive 17	Enrichment	PLEC	1.74
111	Syndactyly, type iii	Enrichment	GJA1	1.74
112	Syndactyly, type v	Enrichment	GJA1	1.74
113	Keratosis palmoplantaris striata ii	Enrichment	DSP	1.74
114	Spondyloepimetaphyseal dysplasia, li-shao-li type	Enrichment	CCN2	1.74
115	Oocyte/zygote/embryo maturation arrest 7	Enrichment	PANX1	1.74
116	Cardiomyopathy, dilated, with woolly hair, keratoderma, and tooth agenesis	Enrichment	DSP	1.74
117	Combined osteogenesis imperfecta and ehlers-danlos syndrome 1	Enrichment	COL1A1	1.74
118	Blepharocheilodontic syndrome 2	Enrichment	CTNND1	1.74
119	Dystonia 30	Enrichment	PTPRA	1.74
120	Epidermolysis bullosa, junctional 5a, intermediate	Enrichment	ITGB4	1.74
121	Ehlers-danlos syndrome, arthrochalasia type, 2	Enrichment	COL1A1	1.74
122	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	1.74
123	Craniometaphyseal dysplasia	Enrichment	GJA1	1.74
124	Autosomal recessive limb-girdle muscular dystrophy type 2q	Enrichment	PLEC	1.74
125	Progressive familial heart block	Enrichment	DSP	1.74
126	Metaphyseal anadysplasia 2	Enrichment	MMP9	1.74
127	Stickler syndrome, type ii	Enrichment	COL1A1	1.74
128	Cardiomyopathy, dilated, with woolly hair and keratoderma	Enrichment	DSP	1.74
129	Hereditary angioedema	Enrichment	PLG	1.74
130	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.74
131	Ehlers-danlos/osteogenesis imperfecta syndrome	Enrichment	COL1A1	1.74
132	Localized junctional epidermolysis bullosa, non-herlitz type	Enrichment	ITGB4	1.74
133	Teratoma	Enrichment	CTNNB1	1.74
134	Malignant peripheral nerve sheath tumor with perineurial differentiation	Enrichment	SH3PXD2A	1.74
135	Malignant triton tumor	Enrichment	SH3PXD2A	1.74
136	Desmoid disease, hereditary	Enrichment	CTNNB1	1.57
137	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	ITGB3	1.57
138	Angioedema, hereditary, 1	Enrichment	PLG	1.57
139	Bleeding disorder, platelet-type, 16	Enrichment	ITGB3	1.57
140	Hypercholanemia, familial 1	Enrichment	TJP2	1.57
141	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.57
142	Caffey disease	Enrichment	COL1A1	1.57
143	Anus, imperforate	Enrichment	CTNNB1	1.57
144	Erythroderma, congenital, with palmoplantar keratoderma, hypotrichosis, and hyper-ige	Enrichment	DSP	1.57
145	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.57
146	Epidermolysis bullosa, junctional 6, with pyloric atresia	Enrichment	ITGA6	1.57
147	Woolly hair-skin fragility syndrome	Enrichment	DSP	1.57
148	Desmoid tumor	Enrichment	CTNNB1	1.57
149	Keratosis palmoplantaris striata	Enrichment	DSP	1.57
150	Epidermolysis bullosa simplex 5d, generalized intermediate, autosomal recessive	Enrichment	PLEC	1.57
151	Butterfly-shaped pigment dystrophy	Enrichment	CTNNA1	1.57
152	High bone mass osteogenesis imperfecta	Enrichment	COL1A1	1.57
153	Bleeding disorder, platelet-type, 24	Enrichment	ITGB3	1.57
154	Ehlers-danlos syndrome, arthrochalasia type, 1	Enrichment	COL1A1	1.45
155	Dowling-degos disease 1	Enrichment	ADAM10	1.45
156	Phenylketonuria	Enrichment	COL1A1	1.45
157	Polyposis syndrome, hereditary mixed, 1	Enrichment	CTNNA1	1.45
158	Pilomatrixoma	Enrichment	CTNNB1	1.45
159	Retinitis pigmentosa 26	Enrichment	ITGA4	1.45
160	Alazami syndrome	Enrichment	CTNNB1	1.45
161	Craniopharyngioma	Enrichment	CTNNB1	1.45
162	Corneal dystrophy	Enrichment	TGFBI	1.45
163	Cerebral malaria	Enrichment	ICAM1	1.45
164	Osteogenesis imperfecta with normal sclerae, dominant form	Enrichment	COL1A1	1.45
165	Pseudomyogenic hemangioendothelioma	Enrichment	SERPINE1	1.45
166	Dilated cardiomyopathy	Enrichment	DSP, JUP, VCL	1.44
167	Epidermolysis bullosa simplex 2f, with mottled pigmentation	Enrichment	PLEC	1.35
168	Epidermolysis bullosa simplex 1a, generalized severe	Enrichment	PLEC	1.35
169	Epidermolysis bullosa simplex 1c, localized	Enrichment	ITGB4	1.35
170	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	1.35
171	Glanzmann thrombasthenia 2	Enrichment	ITGB3	1.35
172	Cardiac arrest	Enrichment	DSP	1.35
173	Epidermolysis bullosa	Enrichment	ITGA6	1.35
174	Cleft upper lip	Enrichment	GJA1	1.35
175	Female infertility due to oocyte meiotic arrest	Enrichment	PANX1	1.35
176	Ehlers-danlos syndrome, classic type, 1	Enrichment	COL1A1	1.27
177	Branchiootorenal syndrome 1	Enrichment	TJP2	1.27
178	Osteogenesis imperfecta, type i	Enrichment	COL1A1	1.27
179	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.27
180	Epidermolysis bullosa, junctional 1a, intermediate	Enrichment	ITGB4	1.27
181	Junctional epidermolysis bullosa non-herlitz type	Enrichment	ITGB4	1.27
182	Keratoconus	Enrichment	COL1A1	1.27
183	Adrenocortical carcinoma	Enrichment	CTNNB1	1.27
184	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	ITGB3	1.27
185	Classic ehlers-danlos syndrome	Enrichment	COL1A1	1.27
186	Familial hypercholanemia	Enrichment	TJP2	1.27
187	Inherited arrhythmogenic cardiomyopathy	Enrichment	DSP	1.27
188	Gastric cancer	Enrichment	CDH1, EPCAM	1.24
189	Hereditary breast carcinoma	Enrichment	CDH1, EPCAM	1.22
190	Osteogenesis imperfecta, type ii	Enrichment	COL1A1	1.21
191	Fundus albipunctatus	Enrichment	CD63	1.21
192	Glanzmann thrombasthenia 1	Enrichment	ITGB3	1.21
193	Branchiootorenal syndrome	Enrichment	TJP2	1.21
194	Gallbladder cancer	Enrichment	CTNNB1	1.21
195	Erythrokeratodermia variabilis et progressiva 1	Enrichment	GJA1	1.15
196	Exudative vitreoretinopathy	Enrichment	CTNNB1	1.15
197	Myocarditis	Enrichment	DSP	1.15
198	Hypoplastic left heart syndrome	Enrichment	GJA1	1.15
199	Arrhythmogenic right ventricular dysplasia, familial, 9	Enrichment	DSP	1.10
200	Adult hepatocellular carcinoma	Enrichment	CTNNB1	1.10
201	Colonic benign neoplasm	Enrichment	EPCAM	1.10
202	Primary biliary cholangitis	Enrichment	TJP2	1.10
203	Familial isolated arrhythmogenic right ventricular dysplasia	Enrichment	DSP	1.10
204	Hypotrichosis simplex	Enrichment	CDH3	1.10
205	Familial isolated dilated cardiomyopathy	Enrichment	DSP, VCL	1.08
206	Lynch syndrome 1	Enrichment	EPCAM	1.06
207	Autosomal dominant macrothrombocytopenia	Enrichment	ITGB3	1.06
208	Primary bone dysplasia	Enrichment	COL1A1	1.06
209	Osteochondrodysplasia	Enrichment	COL1A1	1.02
210	Ichthyosis	Enrichment	ST14	1.02
211	Heritable pulmonary arterial hypertension	Enrichment	CAV1	1.02
212	Cardiac conduction defect	Enrichment	DSP	0.98
213	Aortic valve disease 1	Enrichment	DSP	0.95
214	Osteogenesis imperfecta, type iv	Enrichment	COL1A1	0.95
215	Inherited cancer-predisposing syndrome	Enrichment	CDH1, CTNNA1, EPCAM	0.93
216	Osteoporosis	Enrichment	COL1A1	0.92
217	Medulloblastoma	Enrichment	CTNNB1	0.92
218	Cleft lip/palate	Enrichment	CDH1	0.92
219	Isolated macular dystrophy	Enrichment	ITGA4	0.92
220	Hereditary retinal dystrophy	Enrichment	ADAM9, CD63, CDH3, CTNNA1, ITGA4	0.91
221	Fundus dystrophy	Enrichment	ADAM9, CD63, CDH3, CTNNA1, ITGA4	0.91
222	Cone-rod dystrophy 2	Enrichment	ADAM9, ITGA4	0.90
223	Corpus callosum, agenesis of	Enrichment	CDH2	0.89
224	Osteogenesis imperfecta, type iii	Enrichment	COL1A1	0.89
225	Lynch syndrome	Enrichment	EPCAM	0.89
226	Isolated corpus callosum agenesis	Enrichment	CDH2	0.89
227	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CDH2	0.89
228	Wolff-parkinson-white syndrome	Enrichment	JUP	0.87
229	Hypertension, essential	Enrichment	ATP1B1	0.84
230	Interstitial lung disease 2	Enrichment	DSP	0.84
231	Polycystic liver disease	Enrichment	CTNNB1	0.84
232	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	0.84
233	Breast cancer	Enrichment	CDH1, EPCAM	0.83
234	Arteriovenous malformations of the brain	Enrichment	CDH2	0.80
235	Ehlers-danlos syndrome	Enrichment	COL1A1	0.80
236	Craniosynostosis	Enrichment	CTNNA1	0.78
237	Cardiomyopathy, dilated, 1a	Enrichment	DSP	0.76
238	Endometrial cancer	Enrichment	CDH1	0.76
239	Hepatoblastoma	Enrichment	CTNNB1	0.76
240	Hepatocellular carcinoma	Enrichment	CTNNB1	0.74
241	Cardiomyopathy, dilated, 1g	Enrichment	DSP	0.74
242	Myocardial infarction	Enrichment	ITGB3	0.74
243	Brittle bone disorder	Enrichment	COL1A1	0.72
244	Malaria	Enrichment	ICAM1	0.72
245	Congenital stationary night blindness	Enrichment	CD63	0.72
246	Auditory neuropathy	Enrichment	CDH2	0.68
247	Bladder cancer	Enrichment	CTNNB1	0.63
248	Prostate cancer	Enrichment	CDH1	0.63
249	Severe covid-19	Enrichment	ITGAV	0.63
250	Ovarian cancer	Enrichment	CDH1, CTNNB1	0.63
251	Long qt syndrome 1	Enrichment	DSP	0.62
252	Long qt syndrome	Enrichment	DSP	0.61
253	Cystic fibrosis	Enrichment	PLG	0.60
254	Primary autosomal recessive microcephaly	Enrichment	PDCD6IP	0.60
255	Left ventricular noncompaction	Enrichment	DSP	0.56
256	Non-syndromic x-linked intellectual disability	Enrichment	ARHGEF6	0.55
257	Myopathy	Enrichment	PLEC	0.51
258	Microcephaly	Enrichment	CTNNB1, PPFIBP1	0.51
259	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	COL1A1	0.48
260	Thrombocytopenia	Enrichment	ITGB3	0.45
261	Body mass index quantitative trait locus 11	Enrichment	DIXDC1	0.44
262	Hypertelorism	Enrichment	COL1A1	0.42
263	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	TJP2	0.42
264	Primary ovarian insufficiency	Enrichment	ADAMTS1	0.38
265	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	GJA1	0.25
266	Retinitis pigmentosa	Enrichment	ADAM9, CDH3	0.24
267	Congenital nervous system abnormality	Enrichment	CTNNB1	0.21
268	Nervous system disease	Enrichment	CTNNB1	0.21

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Adhesion

Pathway Network for Adhesion

Member Pathways for Adhesion

Pathways in the Adhesion SuperPath

Associated Genes for Adhesion

Associated Disorders for Adhesion

Disorders associated with Adhesion SuperPath

STRING Interaction Network for Adhesion

Sources for Adhesion