Advanced glycosylation endproduct receptor signaling

No Pathway Network information available for Advanced glycosylation endproduct receptor signaling

#	Name	Source	Genes
1	Advanced glycosylation endproduct receptor signaling	Reactome	AGER APP CAPZA1 CAPZA2 DDOST HMGB1 LGALS3 MAPK1 MAPK3 PRKCSH S100A12 S100B SAA1 (see all 13) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	DDOST	Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Non-Catalytic Subunit	Protein Coding	1
2	AGER	Advanced Glycosylation End-Product Specific Receptor	Protein Coding	1
3	HMGB1	High Mobility Group Box 1	Protein Coding	1
4	APP	Amyloid Beta Precursor Protein	Protein Coding	1
5	LGALS3	Galectin 3	Protein Coding	1
6	PRKCSH	PRKCSH Beta Subunit Of Glucosidase II	Protein Coding	1
7	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
8	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	1
9	S100A12	S100 Calcium Binding Protein A12	Protein Coding	1
10	S100B	S100 Calcium Binding Protein B	Protein Coding	1
11	SAA1	Serum Amyloid A1	Protein Coding	1
12	CAPZA1	Capping Actin Protein Of Muscle Z-Line Subunit Alpha 1	Protein Coding	1
13	CAPZA2	Capping Actin Protein Of Muscle Z-Line Subunit Alpha 2	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Brachyphalangy, polydactyly, and tibial aplasia/hypoplasia	Enrichment	HMGB1	3.02
2	Noonan syndrome 13	Enrichment	MAPK1	3.02
3	Cerebral amyloid angiopathy, app-related	Enrichment	APP	3.02
4	Congenital disorder of glycosylation, type ir	Enrichment	DDOST	3.02
5	Serum amyloid a amyloidosis	Enrichment	SAA1	3.02
6	Cerebral amyloid angiopathy, cst3-related	Enrichment	APP	2.72
7	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	2.42
8	Polycystic liver disease 1 with or without kidney cysts	Enrichment	PRKCSH	2.32
9	Polycystic liver disease 1	Enrichment	PRKCSH	2.32
10	Alzheimer's disease 1	Enrichment	APP	2.17
11	Early-onset autosomal dominant alzheimer disease	Enrichment	APP	2.17
12	Specific learning disability	Enrichment	MAPK1	1.98
13	Alzheimer's disease	Enrichment	APP	1.91
14	Alzheimer disease, familial, 1	Enrichment	APP	1.79
15	Polycystic liver disease	Enrichment	PRKCSH	1.79
16	Autosomal dominant polycystic liver disease	Enrichment	PRKCSH	1.79
17	Heart, malformation of	Enrichment	MAPK1	1.77
18	Microcephaly	Enrichment	MAPK1	0.95

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Advanced glycosylation endproduct receptor signaling