Akt Signaling

Pathway network for the Akt Signaling SuperPath

Sources:

QIAGEN

Pathways in the Akt Signaling SuperPath

#	Name	Source	Genes
1	Akt Signaling	QIAGEN	ACVR1 ACVR2B ACVRL1 AKT1 AKT1S1 AKT2 AKT3 ALK ANGPT1 ANGPT2 ANGPT4 ANGPTL1 ANGPTL6 AR AREG ATF4 ATXN1 ATXN10 ATXN2 ATXN3 ATXN7 AXL BAD BAX BCAP31 BCL2 BDNF BMP1 BMP10 BMP15 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BMP8B BMPR1A BMPR1B BMPR2 BTC BTK CASP9 CCL1 CCL11 CCL13 CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL2 CCL20 CCL21 CCL22 CCL23 CCL24 CCL25 CCL26 CCL27 CCL28 CCL3 CCL3L1 CCL4 CCL4L1 CCL4L2 CCL5 CCL7 CCL8 CCN2 CCND1 CCND2 CCND3 CCR1 CCR10 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCRL2 CD2 CD27 CD28 CD4 CD40 CD40LG CD70 CD80 CDC37 CDKN1A CDKN1B CER1 CHEK1 CHUK CLEC11A CREB1 CREB3 CREB3L4 CRIPTO CSF1 CSF1R CSF2 CSF2RA CSF2RB CSF3 CSF3R CX3CL1 CX3CR1 CXCL1 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL16 CXCL2 CXCL3 CXCL5 CXCL6 CXCL8 CXCL9 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 DAP DDR1 DDR2 DRC4 EGF EGFR EIF4E EIF4EBP1 EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPOR ERBB2 ERBB3 ERBB4 FAS FASLG FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 FOXO1 FPR2 GAB1 GAB2 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRQ GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GMFG GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAS GNB1 GNB2 GNB3 GNB4 GNB5 GNG2 GNG3 GNG4 GNRH1 GNRH2 GPC6 GPR119 GSK3A GSK3B GYS1 GYS2 HDGF HGF HRAS HRH4 HSP90AA1 HTT IGF1 IGF1R IGF2 IGF2-AS IKBKB IKBKE IKBKG IL10 IL10RA IL10RB IL11 IL11RA IL12A IL12B IL12RB1 IL12RB2 IL13 IL13RA1 IL13RA2 IL15 IL15RA IL16 IL17A IL17RA IL17RC IL18 IL18R1 IL19 IL1A IL1B IL1R1 IL2 IL20 IL20RA IL21 IL22 IL22RA1 IL23A IL23R IL24 IL26 IL2RA IL2RB IL2RG IL3 IL3RA IL4 IL4R IL5 IL5RA IL6 IL6R IL7 IL7R IL9 IL9R ILK INSR INSRR IRS1 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 JAK1 KDR KIT KITLG KLF10 KRAS LEFTY1 LEFTY2 LHB LIF LIFR LMTK2 LMTK3 LTA LTBP1 LTBP2 LTBP3 LTBP4 MAP3K5 MAPK8IP1 MDK MDM2 MERTK MET MRAS MST1R MTOR MUSK NCF1 NGF NGFR NOS3 NPTN NRAS NRG1 NRG2 NRG3 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGN OSM OSMR P2RY13 PDE3B PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PDPK1 PENK PF4 PF4V1 PFKFB1 PFKFB2 PFKFB3 PFKFB4 PFKL PFKM PFKP PGF PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PIP PLPP3 PPBP PPBPP2 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R2B PPP2R2C PPP2R3A PPP2R3B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKDC PROK1 PSIP1 PTEN PTK2 PTK2B PTK7 PTN PTPA PXN RAF1 ROR1 ROR2 ROS1 RPS6KB1 RRAS RRAS2 RYK SEMA3A SEMA4B SEMA4G SEMA5A SLC2A4 SPON1 SYK TBRG1 TEK TGFA TGFB1 TGFB2 TGFB3 THEM4 THPO TIE1 TIMP1 TIMP2 TIMP3 TIMP4 TNF TNFAIP6 TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF13C TNFRSF14 TNFRSF17 TNFRSF18 TNFRSF1A TNFRSF1B TNFRSF21 TNFRSF25 TNFRSF4 TNFRSF8 TNFRSF9 TNFSF10 TNFSF11 TNFSF12 TNFSF13 TNFSF13B TNFSF14 TNFSF18 TNFSF4 TNFSF8 TNFSF9 TP53 TSC1 TSC2 TYMP TYRO3 UTS2 VEGFB VEGFC VEGFD WNK1 XCR1 XIAP YAP1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 514) (see less)
2	p38 Signaling	QIAGEN	ACVR1 ACVR2B ACVRL1 ALK ANGPT1 ANGPT2 ANGPT4 ANGPTL1 ANGPTL6 AP2A1 AREG ARHGEF7 ATF2 AXL BAX BCL2 BDNF BMP1 BMP10 BMP15 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BMP8B BMPR1A BMPR1B BMPR2 BTC BTK CASP3 CASP6 CCL1 CCL11 CCL13 CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL2 CCL20 CCL21 CCL22 CCL23 CCL24 CCL25 CCL26 CCL27 CCL28 CCL3 CCL3L1 CCL4 CCL4L1 CCL4L2 CCL5 CCL7 CCL8 CCN2 CCR1 CCR10 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCRL2 CD2 CD247 CD27 CD28 CD3D CD3E CD3G CD4 CD40 CD40LG CD70 CD80 CDC25C CDC42 CEBPA CEBPG CER1 CLEC11A CREB1 CRIPTO CSF1 CSF1R CSF2 CSF2RA CSF2RB CSF3 CSF3R CX3CL1 CX3CR1 CXCL1 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL16 CXCL2 CXCL3 CXCL5 CXCL6 CXCL8 CXCL9 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 DAP DAXX DDIT3 DDR1 DDR2 DRC4 EGF EGFR ELK1 ELK4 EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPOR ERBB2 ERBB3 ERBB4 ETV1 FAS FASLG FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 FOSL1 FPR2 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GMFG GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAT1 GNAT2 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GNRH1 GNRH2 GPC6 GRB2 HDGF HGF HRAS HRH4 HSPB1 IGF1 IGF1R IGF2 IGF2-AS IL10 IL10RA IL10RB IL11 IL11RA IL12A IL12B IL12RB1 IL12RB2 IL13 IL13RA1 IL13RA2 IL15 IL15RA IL16 IL17A IL17RA IL17RC IL18 IL18R1 IL19 IL1A IL1B IL1R1 IL1R2 IL2 IL20 IL20RA IL21 IL22 IL22RA1 IL23A IL23R IL24 IL26 IL2RA IL2RB IL2RG IL3 IL3RA IL4 IL4R IL5 IL5RA IL6 IL6R IL7 IL7R IL9 IL9R INSR INSRR IRAK1 IRAK2 IRAK3 IRAK4 JUNB JUND KDR KIT KITLG KLF10 KRAS LCK LEFTY1 LEFTY2 LHB LIF LIFR LMTK2 LMTK3 LTA LTBP1 LTBP2 LTBP3 LTBP4 MAP2K3 MAP2K6 MAP3K10 MAP3K3 MAP3K4 MAP3K5 MAP3K7 MAP3K8 MAPK11 MAPK12 MAPK13 MAPK14 MAPK8IP2 MAPKAPK2 MAPKAPK3 MAPKAPK5 MAX MDK MEF2A MEF2C MEF2D MERTK MET MKNK1 MKNK2 MRAS MST1R MUSK NFKB1 NGF NGFR NPTN NRAS NRG1 NRG2 NRG3 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGN OSM OSMR PAK1 PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PF4 PF4V1 PGF PIP PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PLPP3 PPBP PPBPP2 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD3 PROK1 PSIP1 PTK7 PTN RAC1 RALA RALB RALGDS RIPK1 ROR1 ROR2 ROS1 RPS6KA5 RRAS RRAS2 RYK SEMA3A SEMA4B SEMA4G SEMA5A SOS1 SOS2 SP1 SPAG9 SPON1 SRC STAT1 TAB1 TAB2 TBRG1 TEK TGFA TGFB1 TGFB2 TGFB3 TGFBR1 THPO TIE1 TIMP1 TIMP2 TIMP3 TIMP4 TNF TNFAIP6 TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF13C TNFRSF14 TNFRSF17 TNFRSF18 TNFRSF1A TNFRSF1B TNFRSF21 TNFRSF25 TNFRSF4 TNFRSF8 TNFRSF9 TNFSF10 TNFSF11 TNFSF12 TNFSF13 TNFSF13B TNFSF14 TNFSF18 TNFSF4 TNFSF8 TNFSF9 TP53 TRADD TRAF2 TRAF6 TYMP TYRO3 UTS2 VEGFB VEGFC VEGFD XCR1 ZAP70 (see all 480) (see less)
3	Tec Kinases Signaling	QIAGEN	ACTA1 ACTA2 ACTB ACTG1 ACTG2 ACVR1 ACVR2B ACVRL1 ANGPT1 ANGPT2 ANGPT4 ANGPTL1 ANGPTL6 AREG BAX BCL2 BDNF BMP1 BMP10 BMP15 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BMP8B BMPR1A BMPR1B BMPR2 BMX BTC BTK CCL1 CCL11 CCL13 CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL2 CCL20 CCL21 CCL22 CCL23 CCL24 CCL25 CCL26 CCL27 CCL28 CCL3 CCL3L1 CCL4 CCL5 CCL7 CCL8 CCN2 CCR1 CCR10 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCRL2 CD2 CD247 CD27 CD28 CD3D CD3E CD3G CD4 CD40 CD80 CDC42 CLEC11A CRIPTO CSF1R CSF2RA CSF2RB CSF3R CX3CR1 CXCL12 CXCL8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 DIRAS3 DRC4 EGF EGFR EPOR ERBB2 ERBB3 ERBB4 FADD FAS FASLG FCER1A FCER1G FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FOS FPR2 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GMFG GNA11 GNA12 GNA13 GNA14 GNA15 GNAS GNB1 GNB2 GNB3 GNB4 GNB5 GNG2 GNG3 GNG4 GNRH1 GNRH2 GPC6 GTF2I HDGF HGF HRH4 IGF1 IGF1R IGF2 IGF2-AS IL10 IL10RA IL10RB IL11 IL11RA IL12A IL12B IL12RB1 IL12RB2 IL13 IL13RA1 IL13RA2 IL15 IL15RA IL16 IL17A IL17RA IL17RC IL18 IL18R1 IL19 IL1A IL1B IL1R1 IL2 IL20 IL20RA IL22 IL22RA1 IL23A IL23R IL24 IL26 IL2RA IL2RB IL2RG IL3 IL3RA IL4 IL4R IL5 IL5RA IL6 IL6R IL7 IL7R IL9 IL9R INSR IRAK1 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 ITK JAK1 JAK2 JAK3 KITLG KLF10 LAT LCP2 LEFTY1 LEFTY2 LHB LIFR LTBP1 LTBP2 LTBP3 LTBP4 MAPK10 MAPK8 MAPK9 MDK MET MYD88 NFKB1 NGF NGFR NPTN NRG1 NRG2 NRG3 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGN OSMR PAK1 PAK2 PAK3 PAK4 PAK5 PAK6 PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLCG1 PLCG2 PLPP3 PPBP PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PROK1 PSIP1 PTK2 PTK2B PTN RAC1 RAC2 RAC3 RHOA RHOB RHOC RHOD RHOG RHOH RHOJ RHOQ RND2 RND3 SEMA3A SEMA4B SEMA4G SEMA5A SPON1 STAT1 STAT2 STAT3 STAT4 STAT5A STAT5B STAT6 SYK TBRG1 TEC TEK TGFA TGFB1 TGFB2 TGFB3 THPO TIE1 TIMP1 TIMP2 TIMP3 TIMP4 TIRAP TLR1 TLR10 TLR2 TLR3 TLR4 TLR5 TLR6 TLR7 TLR8 TLR9 TNF TNFAIP6 TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF13C TNFRSF14 TNFRSF17 TNFRSF18 TNFRSF1A TNFRSF1B TNFRSF21 TNFRSF25 TNFRSF4 TNFRSF8 TNFRSF9 TNFSF10 TNFSF12 TNFSF13B TXK TYMP UTS2 VAV1 VAV2 VAV3 VEGFB VEGFC VEGFD WAS XCR1 (see all 406) (see less)

Gene overlap in member pathways for Akt Signaling SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ACVR1	Activin A Receptor Type 1	Protein Coding	3
2	ACVR2B	Activin A Receptor Type 2B	Protein Coding	3
3	ACVRL1	Activin A Receptor Like Type 1	Protein Coding	3
4	ANGPT1	Angiopoietin 1	Protein Coding	3
5	ANGPT2	Angiopoietin 2	Protein Coding	3
6	ANGPT4	Angiopoietin 4	Protein Coding	3
7	ANGPTL1	Angiopoietin Like 1	Protein Coding	3
8	ANGPTL6	Angiopoietin Like 6	Protein Coding	3
9	AREG	Amphiregulin	Protein Coding	3
10	BAX	BCL2 Associated X, Apoptosis Regulator	Protein Coding	3
11	BCL2	BCL2 Apoptosis Regulator	Protein Coding	3
12	BDNF	Brain Derived Neurotrophic Factor	Protein Coding	3
13	CXCR5	C-X-C Motif Chemokine Receptor 5	Protein Coding	3
14	BMP1	Bone Morphogenetic Protein 1	Protein Coding	3
15	BMP10	Bone Morphogenetic Protein 10	Protein Coding	3
16	BMP15	Bone Morphogenetic Protein 15	Protein Coding	3
17	BMP2	Bone Morphogenetic Protein 2	Protein Coding	3
18	BMP3	Bone Morphogenetic Protein 3	Protein Coding	3
19	BMP4	Bone Morphogenetic Protein 4	Protein Coding	3
20	BMP5	Bone Morphogenetic Protein 5	Protein Coding	3
21	BMP6	Bone Morphogenetic Protein 6	Protein Coding	3
22	BMP7	Bone Morphogenetic Protein 7	Protein Coding	3
23	BMP8B	Bone Morphogenetic Protein 8b	Protein Coding	3
24	BMP8A	Bone Morphogenetic Protein 8a	Protein Coding	3
25	BMPR1A	Bone Morphogenetic Protein Receptor Type 1A	Protein Coding	3
26	BMPR1B	Bone Morphogenetic Protein Receptor Type 1B	Protein Coding	3
27	BMPR2	Bone Morphogenetic Protein Receptor Type 2	Protein Coding	3
28	BTC	Betacellulin	Protein Coding	3
29	BTK	Bruton Tyrosine Kinase	Protein Coding	3
30	CCL1	C-C Motif Chemokine Ligand 1	Protein Coding	3
31	CCL11	C-C Motif Chemokine Ligand 11	Protein Coding	3
32	CCL13	C-C Motif Chemokine Ligand 13	Protein Coding	3
33	CCL14	C-C Motif Chemokine Ligand 14	Protein Coding	3
34	CCL15	C-C Motif Chemokine Ligand 15	Protein Coding	3
35	CCL16	C-C Motif Chemokine Ligand 16	Protein Coding	3
36	CCL17	C-C Motif Chemokine Ligand 17	Protein Coding	3
37	CCL18	C-C Motif Chemokine Ligand 18	Protein Coding	3
38	CCL19	C-C Motif Chemokine Ligand 19	Protein Coding	3
39	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	3
40	CCL20	C-C Motif Chemokine Ligand 20	Protein Coding	3
41	CCL21	C-C Motif Chemokine Ligand 21	Protein Coding	3
42	CCL22	C-C Motif Chemokine Ligand 22	Protein Coding	3
43	CCL23	C-C Motif Chemokine Ligand 23	Protein Coding	3
44	CCL24	C-C Motif Chemokine Ligand 24	Protein Coding	3
45	CCL25	C-C Motif Chemokine Ligand 25	Protein Coding	3
46	CCL26	C-C Motif Chemokine Ligand 26	Protein Coding	3
47	CCL27	C-C Motif Chemokine Ligand 27	Protein Coding	3
48	CCL28	C-C Motif Chemokine Ligand 28	Protein Coding	3
49	CCL3	C-C Motif Chemokine Ligand 3	Protein Coding	3
50	CCL3L1	C-C Motif Chemokine Ligand 3 Like 1	Protein Coding	3
51	CCL4	C-C Motif Chemokine Ligand 4	Protein Coding	3
52	CCL5	C-C Motif Chemokine Ligand 5	Protein Coding	3
53	CCL7	C-C Motif Chemokine Ligand 7	Protein Coding	3
54	CCL8	C-C Motif Chemokine Ligand 8	Protein Coding	3
55	CCR1	C-C Motif Chemokine Receptor 1	Protein Coding	3
56	CCR2	C-C Motif Chemokine Receptor 2	Protein Coding	3
57	CCR3	C-C Motif Chemokine Receptor 3	Protein Coding	3
58	CCR4	C-C Motif Chemokine Receptor 4	Protein Coding	3
59	CCR5	C-C Motif Chemokine Receptor 5	Protein Coding	3
60	CCR6	C-C Motif Chemokine Receptor 6	Protein Coding	3
61	CCR7	C-C Motif Chemokine Receptor 7	Protein Coding	3
62	CCR8	C-C Motif Chemokine Receptor 8	Protein Coding	3
63	CCR9	C-C Motif Chemokine Receptor 9	Protein Coding	3
64	CCRL2	C-C Motif Chemokine Receptor Like 2	Protein Coding	3
65	CD2	CD2 Molecule	Protein Coding	3
66	CD28	CD28 Molecule	Protein Coding	3
67	CD4	CD4 Molecule	Protein Coding	3
68	CD80	CD80 Molecule	Protein Coding	3
69	CSF1R	Colony Stimulating Factor 1 Receptor	Protein Coding	3
70	CSF2RA	Colony Stimulating Factor 2 Receptor Subunit Alpha	Protein Coding	3
71	CSF2RB	Colony Stimulating Factor 2 Receptor Subunit Beta	Protein Coding	3
72	CSF3R	Colony Stimulating Factor 3 Receptor	Protein Coding	3
73	CCN2	Cellular Communication Network Factor 2	Protein Coding	3
74	CX3CR1	C-X3-C Motif Chemokine Receptor 1	Protein Coding	3
75	CXCL12	C-X-C Motif Chemokine Ligand 12	Protein Coding	3
76	CXCR3	C-X-C Motif Chemokine Receptor 3	Protein Coding	3
77	CXCR4	C-X-C Motif Chemokine Receptor 4	Protein Coding	3
78	CXCR6	C-X-C Motif Chemokine Receptor 6	Protein Coding	3
79	LEFTY2	Left-Right Determination Factor 2	Protein Coding	3
80	TYMP	Thymidine Phosphorylase	Protein Coding	3
81	EGF	Epidermal Growth Factor	Protein Coding	3
82	EGFR	Epidermal Growth Factor Receptor	Protein Coding	3
83	EPOR	Erythropoietin Receptor	Protein Coding	3
84	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	Protein Coding	3
85	ERBB3	Erb-B2 Receptor Tyrosine Kinase 3	Protein Coding	3
86	ERBB4	Erb-B2 Receptor Tyrosine Kinase 4	Protein Coding	3
87	FGF1	Fibroblast Growth Factor 1	Protein Coding	3
88	FGF10	Fibroblast Growth Factor 10	Protein Coding	3
89	FGF11	Fibroblast Growth Factor 11	Protein Coding	3
90	FGF12	Fibroblast Growth Factor 12	Protein Coding	3
91	FGF13	Fibroblast Growth Factor 13	Protein Coding	3
92	FGF14	Fibroblast Growth Factor 14	Protein Coding	3
93	FGF16	Fibroblast Growth Factor 16	Protein Coding	3
94	FGF17	Fibroblast Growth Factor 17	Protein Coding	3
95	FGF18	Fibroblast Growth Factor 18	Protein Coding	3
96	FGF19	Fibroblast Growth Factor 19	Protein Coding	3
97	FGF2	Fibroblast Growth Factor 2	Protein Coding	3
98	FGF20	Fibroblast Growth Factor 20	Protein Coding	3
99	FGF21	Fibroblast Growth Factor 21	Protein Coding	3
100	FGF22	Fibroblast Growth Factor 22	Protein Coding	3
101	FGF23	Fibroblast Growth Factor 23	Protein Coding	3
102	FGF4	Fibroblast Growth Factor 4	Protein Coding	3
103	FGF5	Fibroblast Growth Factor 5	Protein Coding	3
104	FGF6	Fibroblast Growth Factor 6	Protein Coding	3
105	FGF7	Fibroblast Growth Factor 7	Protein Coding	3
106	FGF8	Fibroblast Growth Factor 8	Protein Coding	3
107	FGFR1	Fibroblast Growth Factor Receptor 1	Protein Coding	3
108	FGFR2	Fibroblast Growth Factor Receptor 2	Protein Coding	3
109	FGFR3	Fibroblast Growth Factor Receptor 3	Protein Coding	3
110	FGFR4	Fibroblast Growth Factor Receptor 4	Protein Coding	3
111	VEGFD	Vascular Endothelial Growth Factor D	Protein Coding	3
112	FPR2	Formyl Peptide Receptor 2	Protein Coding	3
113	GAS1	Growth Arrest Specific 1	Protein Coding	3
114	GAS2	Growth Arrest Specific 2	Protein Coding	3
115	GAS6	Growth Arrest Specific 6	Protein Coding	3
116	DRC4	Dynein Regulatory Complex Subunit 4	Protein Coding	3
117	GDF10	Growth Differentiation Factor 10	Protein Coding	3
118	GDF2	Growth Differentiation Factor 2	Protein Coding	3
119	GDF5	Growth Differentiation Factor 5	Protein Coding	3
120	GDF6	Growth Differentiation Factor 6	Protein Coding	3
121	GDF9	Growth Differentiation Factor 9	Protein Coding	3
122	GFER	Growth Factor, Augmenter Of Liver Regeneration	Protein Coding	3
123	GH1	Growth Hormone 1	Protein Coding	3
124	GH2	Growth Hormone 2	Protein Coding	3
125	GHRH	Growth Hormone Releasing Hormone	Protein Coding	3
126	GMFG	Glia Maturation Factor Gamma	Protein Coding	3
127	GNA11	G Protein Subunit Alpha 11	Protein Coding	3
128	GNA12	G Protein Subunit Alpha 12	Protein Coding	3
129	GNA13	G Protein Subunit Alpha 13	Protein Coding	3
130	GNA14	G Protein Subunit Alpha 14	Protein Coding	3
131	GNA15	G Protein Subunit Alpha 15	Protein Coding	3
132	GNAS	GNAS Complex Locus	Protein Coding	3
133	GNB1	G Protein Subunit Beta 1	Protein Coding	3
134	GNB2	G Protein Subunit Beta 2	Protein Coding	3
135	GNB3	G Protein Subunit Beta 3	Protein Coding	3
136	GNB4	G Protein Subunit Beta 4	Protein Coding	3
137	GNB5	G Protein Subunit Beta 5	Protein Coding	3
138	GNG2	G Protein Subunit Gamma 2	Protein Coding	3
139	GNG3	G Protein Subunit Gamma 3	Protein Coding	3
140	GNG4	G Protein Subunit Gamma 4	Protein Coding	3
141	GNRH1	Gonadotropin Releasing Hormone 1	Protein Coding	3
142	GNRH2	Gonadotropin Releasing Hormone 2	Protein Coding	3
143	GPC6	Glypican 6	Protein Coding	3
144	CCR10	C-C Motif Chemokine Receptor 10	Protein Coding	3
145	HDGF	Heparin Binding Growth Factor	Protein Coding	3
146	HGF	Hepatocyte Growth Factor	Protein Coding	3
147	HRH4	Histamine Receptor H4	Protein Coding	3
148	IGF1	Insulin Like Growth Factor 1	Protein Coding	3
149	IGF1R	Insulin Like Growth Factor 1 Receptor	Protein Coding	3
150	IGF2	Insulin Like Growth Factor 2	Protein Coding	3
151	IGF2-AS	IGF2 Antisense RNA	RNA Gene	3
152	IL10	Interleukin 10	Protein Coding	3
153	IL10RA	Interleukin 10 Receptor Subunit Alpha	Protein Coding	3
154	IL10RB	Interleukin 10 Receptor Subunit Beta	Protein Coding	3
155	IL11	Interleukin 11	Protein Coding	3
156	IL11RA	Interleukin 11 Receptor Subunit Alpha	Protein Coding	3
157	IL12A	Interleukin 12A	Protein Coding	3
158	IL12B	Interleukin 12B	Protein Coding	3
159	IL12RB1	Interleukin 12 Receptor Subunit Beta 1	Protein Coding	3
160	IL12RB2	Interleukin 12 Receptor Subunit Beta 2	Protein Coding	3
161	IL13	Interleukin 13	Protein Coding	3
162	IL13RA1	Interleukin 13 Receptor Subunit Alpha 1	Protein Coding	3
163	IL13RA2	Interleukin 13 Receptor Subunit Alpha 2	Protein Coding	3
164	IL15	Interleukin 15	Protein Coding	3
165	IL15RA	Interleukin 15 Receptor Subunit Alpha	Protein Coding	3
166	IL16	Interleukin 16	Protein Coding	3
167	IL17A	Interleukin 17A	Protein Coding	3
168	IL17RA	Interleukin 17 Receptor A	Protein Coding	3
169	IL17RC	Interleukin 17 Receptor C	Protein Coding	3
170	IL18	Interleukin 18	Protein Coding	3
171	IL18R1	Interleukin 18 Receptor 1	Protein Coding	3
172	IL19	Interleukin 19	Protein Coding	3
173	IL1A	Interleukin 1 Alpha	Protein Coding	3
174	IL1B	Interleukin 1 Beta	Protein Coding	3
175	IL1R1	Interleukin 1 Receptor Type 1	Protein Coding	3
176	IL2	Interleukin 2	Protein Coding	3
177	IL20	Interleukin 20	Protein Coding	3
178	IL20RA	Interleukin 20 Receptor Subunit Alpha	Protein Coding	3
179	IL22	Interleukin 22	Protein Coding	3
180	IL22RA1	Interleukin 22 Receptor Subunit Alpha 1	Protein Coding	3
181	IL23A	Interleukin 23 Subunit Alpha	Protein Coding	3
182	IL23R	Interleukin 23 Receptor	Protein Coding	3
183	IL24	Interleukin 24	Protein Coding	3
184	IL26	Interleukin 26	Protein Coding	3
185	IL2RA	Interleukin 2 Receptor Subunit Alpha	Protein Coding	3
186	IL2RB	Interleukin 2 Receptor Subunit Beta	Protein Coding	3
187	IL2RG	Interleukin 2 Receptor Subunit Gamma	Protein Coding	3
188	IL3	Interleukin 3	Protein Coding	3
189	IL3RA	Interleukin 3 Receptor Subunit Alpha	Protein Coding	3
190	IL4	Interleukin 4	Protein Coding	3
191	IL4R	Interleukin 4 Receptor	Protein Coding	3
192	IL5	Interleukin 5	Protein Coding	3
193	IL5RA	Interleukin 5 Receptor Subunit Alpha	Protein Coding	3
194	IL6	Interleukin 6	Protein Coding	3
195	IL6R	Interleukin 6 Receptor	Protein Coding	3
196	IL7	Interleukin 7	Protein Coding	3
197	IL7R	Interleukin 7 Receptor	Protein Coding	3
198	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	3
199	CXCR1	C-X-C Motif Chemokine Receptor 1	Protein Coding	3
200	CXCR2	C-X-C Motif Chemokine Receptor 2	Protein Coding	3
201	IL9	Interleukin 9	Protein Coding	3
202	IL9R	Interleukin 9 Receptor	Protein Coding	3
203	INSR	Insulin Receptor	Protein Coding	3
204	KITLG	KIT Ligand	Protein Coding	3
205	LEFTY1	Left-Right Determination Factor 1	Protein Coding	3
206	LHB	Luteinizing Hormone Subunit Beta	Protein Coding	3
207	LIFR	LIF Receptor Subunit Alpha	Protein Coding	3
208	LTBP1	Latent Transforming Growth Factor Beta Binding Protein 1	Protein Coding	3
209	LTBP2	Latent Transforming Growth Factor Beta Binding Protein 2	Protein Coding	3
210	LTBP3	Latent Transforming Growth Factor Beta Binding Protein 3	Protein Coding	3
211	LTBP4	Latent Transforming Growth Factor Beta Binding Protein 4	Protein Coding	3
212	MDK	Midkine	Protein Coding	3
213	MET	MET Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	3
214	NGF	Nerve Growth Factor	Protein Coding	3
215	NGFR	Nerve Growth Factor Receptor	Protein Coding	3
216	NRG1	Neuregulin 1	Protein Coding	3
217	NRG2	Neuregulin 2	Protein Coding	3
218	NRG3	Neuregulin 3	Protein Coding	3
219	NTF3	Neurotrophin 3	Protein Coding	3
220	NTF4	Neurotrophin 4	Protein Coding	3
221	NTRK1	Neurotrophic Receptor Tyrosine Kinase 1	Protein Coding	3
222	NTRK2	Neurotrophic Receptor Tyrosine Kinase 2	Protein Coding	3
223	NTRK3	Neurotrophic Receptor Tyrosine Kinase 3	Protein Coding	3
224	NUDT6	Nudix Hydrolase 6	Protein Coding	3
225	OGN	Osteoglycin	Protein Coding	3
226	OSMR	Oncostatin M Receptor	Protein Coding	3
227	PDGFA	Platelet Derived Growth Factor Subunit A	Protein Coding	3
228	PDGFB	Platelet Derived Growth Factor Subunit B	Protein Coding	3
229	PDGFC	Platelet Derived Growth Factor C	Protein Coding	3
230	PDGFRA	Platelet Derived Growth Factor Receptor Alpha	Protein Coding	3
231	PDGFRB	Platelet Derived Growth Factor Receptor Beta	Protein Coding	3
232	PENK	Proenkephalin	Protein Coding	3
233	PGF	Placental Growth Factor	Protein Coding	3
234	GDF15	Growth Differentiation Factor 15	Protein Coding	3
235	PLPP3	Phospholipid Phosphatase 3	Protein Coding	3
236	PPBP	Pro-Platelet Basic Protein	Protein Coding	3
237	PROK1	Prokineticin 1	Protein Coding	3
238	PSIP1	PC4 And SRSF1 Interacting Protein 1	Protein Coding	3
239	PTN	Pleiotrophin	Protein Coding	3
240	PDGFD	Platelet Derived Growth Factor D	Protein Coding	3
241	CLEC11A	C-Type Lectin Domain Containing 11A	Protein Coding	3
242	NPTN	Neuroplastin	Protein Coding	3
243	SEMA3A	Semaphorin 3A	Protein Coding	3
244	SEMA4B	Semaphorin 4B	Protein Coding	3
245	SEMA4G	Semaphorin 4G	Protein Coding	3
246	SEMA5A	Semaphorin 5A	Protein Coding	3
247	SPON1	Spondin 1	Protein Coding	3
248	TBRG1	Transforming Growth Factor Beta Regulator 1	Protein Coding	3
249	CRIPTO	Cripto, EGF-CFC Family Member	Protein Coding	3
250	TEK	TEK Receptor Tyrosine Kinase	Protein Coding	3
251	TGFA	Transforming Growth Factor Alpha	Protein Coding	3
252	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	3
253	TGFB2	Transforming Growth Factor Beta 2	Protein Coding	3
254	TGFB3	Transforming Growth Factor Beta 3	Protein Coding	3
255	THPO	Thrombopoietin	Protein Coding	3
256	TIE1	Tyrosine Kinase With Immunoglobulin Like And EGF Like Domains 1	Protein Coding	3
257	KLF10	KLF Transcription Factor 10	Protein Coding	3
258	TIMP1	TIMP Metallopeptidase Inhibitor 1	Protein Coding	3
259	TIMP2	TIMP Metallopeptidase Inhibitor 2	Protein Coding	3
260	TIMP3	TIMP Metallopeptidase Inhibitor 3	Protein Coding	3
261	TIMP4	TIMP Metallopeptidase Inhibitor 4	Protein Coding	3
262	TNF	Tumor Necrosis Factor	Protein Coding	3
263	TNFAIP6	TNF Alpha Induced Protein 6	Protein Coding	3
264	TNFRSF10A	TNF Receptor Superfamily Member 10a	Protein Coding	3
265	TNFRSF10B	TNF Receptor Superfamily Member 10b	Protein Coding	3
266	TNFRSF10C	TNF Receptor Superfamily Member 10c	Protein Coding	3
267	TNFRSF10D	TNF Receptor Superfamily Member 10d	Protein Coding	3
268	TNFRSF11A	TNF Receptor Superfamily Member 11a	Protein Coding	3
269	TNFRSF25	TNF Receptor Superfamily Member 25	Protein Coding	3
270	TNFRSF12A	TNF Receptor Superfamily Member 12A	Protein Coding	3
271	TNFRSF13B	TNF Receptor Superfamily Member 13B	Protein Coding	3
272	TNFRSF13C	TNF Receptor Superfamily Member 13C	Protein Coding	3
273	TNFRSF14	TNF Receptor Superfamily Member 14	Protein Coding	3
274	TNFRSF17	TNF Receptor Superfamily Member 17	Protein Coding	3
275	TNFRSF18	TNF Receptor Superfamily Member 18	Protein Coding	3
276	TNFRSF1A	TNF Receptor Superfamily Member 1A	Protein Coding	3
277	TNFRSF1B	TNF Receptor Superfamily Member 1B	Protein Coding	3
278	TNFRSF21	TNF Receptor Superfamily Member 21	Protein Coding	3
279	TNFRSF4	TNF Receptor Superfamily Member 4	Protein Coding	3
280	CD40	CD40 Molecule	Protein Coding	3
281	FAS	Fas Cell Surface Death Receptor	Protein Coding	3
282	CD27	CD27 Molecule	Protein Coding	3
283	TNFRSF8	TNF Receptor Superfamily Member 8	Protein Coding	3
284	TNFRSF9	TNF Receptor Superfamily Member 9	Protein Coding	3
285	TNFSF10	TNF Superfamily Member 10	Protein Coding	3
286	TNFSF12	TNF Superfamily Member 12	Protein Coding	3
287	TNFSF13B	TNF Superfamily Member 13b	Protein Coding	3
288	FASLG	Fas Ligand	Protein Coding	3
289	UTS2	Urotensin 2	Protein Coding	3
290	VEGFB	Vascular Endothelial Growth Factor B	Protein Coding	3
291	VEGFC	Vascular Endothelial Growth Factor C	Protein Coding	3
292	XCR1	X-C Motif Chemokine Receptor 1	Protein Coding	3
293	ALK	ALK Receptor Tyrosine Kinase	Protein Coding	2
294	AXL	AXL Receptor Tyrosine Kinase	Protein Coding	2
295	CCL4L1	C-C Motif Chemokine Ligand 4 Like 1	Protein Coding	2
296	CCL4L2	C-C Motif Chemokine Ligand 4 Like 2	Protein Coding	2
297	CER1	Cerberus 1, DAN Family BMP Antagonist	Protein Coding	2
298	CREB1	CAMP Responsive Element Binding Protein 1	Protein Coding	2
299	CSF1	Colony Stimulating Factor 1	Protein Coding	2
300	CSF2	Colony Stimulating Factor 2	Protein Coding	2
301	CSF3	Colony Stimulating Factor 3	Protein Coding	2
302	CX3CL1	C-X3-C Motif Chemokine Ligand 1	Protein Coding	2
303	CXCL1	C-X-C Motif Chemokine Ligand 1	Protein Coding	2
304	CXCL10	C-X-C Motif Chemokine Ligand 10	Protein Coding	2
305	CXCL11	C-X-C Motif Chemokine Ligand 11	Protein Coding	2
306	CXCL13	C-X-C Motif Chemokine Ligand 13	Protein Coding	2
307	CXCL14	C-X-C Motif Chemokine Ligand 14	Protein Coding	2
308	CXCL16	C-X-C Motif Chemokine Ligand 16	Protein Coding	2
309	CXCL2	C-X-C Motif Chemokine Ligand 2	Protein Coding	2
310	CXCL3	C-X-C Motif Chemokine Ligand 3	Protein Coding	2
311	CXCL5	C-X-C Motif Chemokine Ligand 5	Protein Coding	2
312	CXCL6	C-X-C Motif Chemokine Ligand 6	Protein Coding	2
313	CXCL9	C-X-C Motif Chemokine Ligand 9	Protein Coding	2
314	DAP	Death Associated Protein	Protein Coding	2
315	DDR1	Discoidin Domain Receptor Tyrosine Kinase 1	Protein Coding	2
316	DDR2	Discoidin Domain Receptor Tyrosine Kinase 2	Protein Coding	2
317	EPHA1	EPH Receptor A1	Protein Coding	2
318	EPHA2	EPH Receptor A2	Protein Coding	2
319	EPHA3	EPH Receptor A3	Protein Coding	2
320	EPHA4	EPH Receptor A4	Protein Coding	2
321	EPHA5	EPH Receptor A5	Protein Coding	2
322	EPHA7	EPH Receptor A7	Protein Coding	2
323	EPHA8	EPH Receptor A8	Protein Coding	2
324	EPHB1	EPH Receptor B1	Protein Coding	2
325	EPHB2	EPH Receptor B2	Protein Coding	2
326	EPHB3	EPH Receptor B3	Protein Coding	2
327	EPHB4	EPH Receptor B4	Protein Coding	2
328	EPHB6	EPH Receptor B6	Protein Coding	2
329	FLT1	Fms Related Receptor Tyrosine Kinase 1	Protein Coding	2
330	FLT3	Fms Related Receptor Tyrosine Kinase 3	Protein Coding	2
331	FLT4	Fms Related Receptor Tyrosine Kinase 4	Protein Coding	2
332	GNAI1	G Protein Subunit Alpha I1	Protein Coding	2
333	GNAI2	G Protein Subunit Alpha I2	Protein Coding	2
334	GNAI3	G Protein Subunit Alpha I3	Protein Coding	2
335	GNAL	G Protein Subunit Alpha L	Protein Coding	2
336	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	2
337	IL21	Interleukin 21	Protein Coding	2
338	INSRR	Insulin Receptor Related Receptor	Protein Coding	2
339	ITGA1	Integrin Subunit Alpha 1	Protein Coding	2
340	ITGA10	Integrin Subunit Alpha 10	Protein Coding	2
341	ITGA11	Integrin Subunit Alpha 11	Protein Coding	2
342	ITGA2	Integrin Subunit Alpha 2	Protein Coding	2
343	ITGA2B	Integrin Subunit Alpha 2b	Protein Coding	2
344	ITGA3	Integrin Subunit Alpha 3	Protein Coding	2
345	ITGA4	Integrin Subunit Alpha 4	Protein Coding	2
346	ITGA5	Integrin Subunit Alpha 5	Protein Coding	2
347	ITGA6	Integrin Subunit Alpha 6	Protein Coding	2
348	ITGA7	Integrin Subunit Alpha 7	Protein Coding	2
349	ITGA8	Integrin Subunit Alpha 8	Protein Coding	2
350	ITGA9	Integrin Subunit Alpha 9	Protein Coding	2
351	ITGAD	Integrin Subunit Alpha D	Protein Coding	2
352	ITGAE	Integrin Subunit Alpha E	Protein Coding	2
353	ITGAL	Integrin Subunit Alpha L	Protein Coding	2
354	ITGAM	Integrin Subunit Alpha M	Protein Coding	2
355	ITGAV	Integrin Subunit Alpha V	Protein Coding	2
356	ITGAX	Integrin Subunit Alpha X	Protein Coding	2
357	ITGB1	Integrin Subunit Beta 1	Protein Coding	2
358	ITGB2	Integrin Subunit Beta 2	Protein Coding	2
359	ITGB3	Integrin Subunit Beta 3	Protein Coding	2
360	ITGB4	Integrin Subunit Beta 4	Protein Coding	2
361	ITGB5	Integrin Subunit Beta 5	Protein Coding	2
362	ITGB6	Integrin Subunit Beta 6	Protein Coding	2
363	ITGB7	Integrin Subunit Beta 7	Protein Coding	2
364	ITGB8	Integrin Subunit Beta 8	Protein Coding	2
365	JAK1	Janus Kinase 1	Protein Coding	2
366	KDR	Kinase Insert Domain Receptor	Protein Coding	2
367	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	2
368	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	2
369	LIF	LIF Interleukin 6 Family Cytokine	Protein Coding	2
370	LMTK2	Lemur Tyrosine Kinase 2	Protein Coding	2
371	LMTK3	Lemur Tyrosine Kinase 3	Protein Coding	2
372	LTA	Lymphotoxin Alpha	Protein Coding	2
373	MAP3K5	Mitogen-Activated Protein Kinase Kinase Kinase 5	Protein Coding	2
374	MERTK	MER Proto-Oncogene, Tyrosine Kinase	Protein Coding	2
375	MRAS	Muscle RAS Oncogene Homolog	Protein Coding	2
376	MST1R	Macrophage Stimulating 1 Receptor	Protein Coding	2
377	MUSK	Muscle Associated Receptor Tyrosine Kinase	Protein Coding	2
378	NRAS	NRAS Proto-Oncogene, GTPase	Protein Coding	2
379	OSM	Oncostatin M	Protein Coding	2
380	PIK3R5	Phosphoinositide-3-Kinase Regulatory Subunit 5	Protein Coding	2
381	PF4	Platelet Factor 4	Protein Coding	2
382	PF4V1	Platelet Factor 4 Variant 1	Protein Coding	2
383	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	2
384	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	2
385	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	2
386	PIK3R4	Phosphoinositide-3-Kinase Regulatory Subunit 4	Protein Coding	2
387	PIP	Prolactin Induced Protein	Protein Coding	2
388	PPBPP2	Pro-Platelet Basic Protein Pseudogene 2	Pseudogene	2
389	PTK2	Protein Tyrosine Kinase 2	Protein Coding	2
390	PTK2B	Protein Tyrosine Kinase 2 Beta	Protein Coding	2
391	PTK7	Protein Tyrosine Kinase 7 (Inactive)	Protein Coding	2
392	ROR1	Receptor Tyrosine Kinase Like Orphan Receptor 1	Protein Coding	2
393	ROR2	Receptor Tyrosine Kinase Like Orphan Receptor 2	Protein Coding	2
394	ROS1	ROS Proto-Oncogene 1, Receptor Tyrosine Kinase	Protein Coding	2
395	RRAS	RAS Related	Protein Coding	2
396	RRAS2	RAS Related 2	Protein Coding	2
397	RYK	Receptor Like Tyrosine Kinase	Protein Coding	2
398	SYK	Spleen Associated Tyrosine Kinase	Protein Coding	2
399	TNFSF11	TNF Superfamily Member 11	Protein Coding	2
400	TNFSF13	TNF Superfamily Member 13	Protein Coding	2
401	TNFSF14	TNF Superfamily Member 14	Protein Coding	2
402	TNFSF18	TNF Superfamily Member 18	Protein Coding	2
403	TNFSF4	TNF Superfamily Member 4	Protein Coding	2
404	CD40LG	CD40 Ligand	Protein Coding	2
405	CD70	CD70 Molecule	Protein Coding	2
406	TNFSF8	TNF Superfamily Member 8	Protein Coding	2
407	TNFSF9	TNF Superfamily Member 9	Protein Coding	2
408	TP53	Tumor Protein P53	Protein Coding	2
409	TYRO3	TYRO3 Protein Tyrosine Kinase	Protein Coding	2
410	CD3D	CD3 Delta Subunit Of T-Cell Receptor Complex	Protein Coding	2
411	CD3E	CD3 Epsilon Subunit Of T-Cell Receptor Complex	Protein Coding	2
412	CD3G	CD3 Gamma Subunit Of T-Cell Receptor Complex	Protein Coding	2
413	CD247	CD247 Molecule	Protein Coding	2
414	CDC42	Cell Division Cycle 42	Protein Coding	2
415	IRAK1	Interleukin 1 Receptor Associated Kinase 1	Protein Coding	2
416	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	2
417	PAK1	P21 (RAC1) Activated Kinase 1	Protein Coding	2
418	PLCG1	Phospholipase C Gamma 1	Protein Coding	2
419	PLCG2	Phospholipase C Gamma 2	Protein Coding	2
420	PRKCA	Protein Kinase C Alpha	Protein Coding	2
421	PRKCB	Protein Kinase C Beta	Protein Coding	2
422	PRKCD	Protein Kinase C Delta	Protein Coding	2
423	PRKCE	Protein Kinase C Epsilon	Protein Coding	2
424	PRKCG	Protein Kinase C Gamma	Protein Coding	2
425	PRKCH	Protein Kinase C Eta	Protein Coding	2
426	RAC1	Rac Family Small GTPase 1	Protein Coding	2
427	STAT1	Signal Transducer And Activator Of Transcription 1	Protein Coding	2
428	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
429	AKT1S1	AKT1 Substrate 1	Protein Coding	1
430	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	1
431	AKT3	AKT Serine/Threonine Kinase 3	Protein Coding	1
432	AR	Androgen Receptor	Protein Coding	1
433	ATF4	Activating Transcription Factor 4	Protein Coding	1
434	BAD	BCL2 Associated Agonist Of Cell Death	Protein Coding	1
435	XIAP	X-Linked Inhibitor Of Apoptosis	Protein Coding	1
436	CASP9	Caspase 9	Protein Coding	1
437	CCND1	Cyclin D1	Protein Coding	1
438	CCND2	Cyclin D2	Protein Coding	1
439	CCND3	Cyclin D3	Protein Coding	1
440	CDC37	Cell Division Cycle 37, HSP90 Cochaperone	Protein Coding	1
441	CDKN1A	Cyclin Dependent Kinase Inhibitor 1A	Protein Coding	1
442	CDKN1B	Cyclin Dependent Kinase Inhibitor 1B	Protein Coding	1
443	CHEK1	Checkpoint Kinase 1	Protein Coding	1
444	CHUK	Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex	Protein Coding	1
445	CREB3	CAMP Responsive Element Binding Protein 3	Protein Coding	1
446	CREB3L4	CAMP Responsive Element Binding Protein 3 Like 4	Protein Coding	1
447	THEM4	Thioesterase Superfamily Member 4	Protein Coding	1
448	BCAP31	B Cell Receptor Associated Protein 31	Protein Coding	1
449	ATXN10	Ataxin 10	Protein Coding	1
450	EIF4E	Eukaryotic Translation Initiation Factor 4E	Protein Coding	1
451	EIF4EBP1	Eukaryotic Translation Initiation Factor 4E Binding Protein 1	Protein Coding	1
452	FOXO1	Forkhead Box O1	Protein Coding	1
453	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	1
454	GAB1	GRB2 Associated Binding Protein 1	Protein Coding	1
455	GAB2	GRB2 Associated Binding Protein 2	Protein Coding	1
456	GABRA1	Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha1	Protein Coding	1
457	GABRA2	Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha2	Protein Coding	1
458	GABRA3	Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha3	Protein Coding	1
459	GABRA4	Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha4	Protein Coding	1
460	GABRA5	Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha5	Protein Coding	1
461	GABRA6	Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha6	Protein Coding	1
462	GABRB1	Gamma-Aminobutyric Acid Type A Receptor Subunit Beta1	Protein Coding	1
463	GABRB2	Gamma-Aminobutyric Acid Type A Receptor Subunit Beta2	Protein Coding	1
464	GABRB3	Gamma-Aminobutyric Acid Type A Receptor Subunit Beta3	Protein Coding	1
465	GABRD	Gamma-Aminobutyric Acid Type A Receptor Subunit Delta	Protein Coding	1
466	GABRE	Gamma-Aminobutyric Acid Type A Receptor Subunit Epsilon	Protein Coding	1
467	GABRG1	Gamma-Aminobutyric Acid Type A Receptor Subunit Gamma1	Protein Coding	1
468	GABRG2	Gamma-Aminobutyric Acid Type A Receptor Subunit Gamma2	Protein Coding	1
469	GABRG3	Gamma-Aminobutyric Acid Type A Receptor Subunit Gamma3	Protein Coding	1
470	GABRQ	Gamma-Aminobutyric Acid Type A Receptor Subunit Theta	Protein Coding	1
471	GPR119	G Protein-Coupled Receptor 119	Protein Coding	1
472	P2RY13	Purinergic Receptor P2Y13	Protein Coding	1
473	GSK3A	Glycogen Synthase Kinase 3 Alpha	Protein Coding	1
474	GSK3B	Glycogen Synthase Kinase 3 Beta	Protein Coding	1
475	GYS1	Glycogen Synthase 1	Protein Coding	1
476	GYS2	Glycogen Synthase 2	Protein Coding	1
477	HTT	Huntingtin	Protein Coding	1
478	HSP90AA1	Heat Shock Protein 90 Alpha Family Class A Member 1	Protein Coding	1
479	IKBKB	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Beta	Protein Coding	1
480	IKBKE	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Epsilon	Protein Coding	1
481	IKBKG	Inhibitor Of Nuclear Factor Kappa B Kinase Regulatory Subunit Gamma	Protein Coding	1
482	ILK	Integrin Linked Kinase	Protein Coding	1
483	IRS1	Insulin Receptor Substrate 1	Protein Coding	1
484	MAPK8IP1	Mitogen-Activated Protein Kinase 8 Interacting Protein 1	Protein Coding	1
485	MDM2	MDM2 Proto-Oncogene	Protein Coding	1
486	ATXN3	Ataxin 3	Protein Coding	1
487	NCF1	Neutrophil Cytosolic Factor 1	Protein Coding	1
488	NOS3	Nitric Oxide Synthase 3	Protein Coding	1
489	PDE3B	Phosphodiesterase 3B	Protein Coding	1
490	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	1
491	PFKFB1	6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 1	Protein Coding	1
492	PFKFB2	6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 2	Protein Coding	1
493	PFKFB3	6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3	Protein Coding	1
494	PFKFB4	6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 4	Protein Coding	1
495	PFKL	Phosphofructokinase, Liver Type	Protein Coding	1
496	PFKM	Phosphofructokinase, Muscle	Protein Coding	1
497	PFKP	Phosphofructokinase, Platelet	Protein Coding	1
498	PIK3CG	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma	Protein Coding	1
499	PPP2CA	Protein Phosphatase 2 Catalytic Subunit Alpha	Protein Coding	1
500	PPP2CB	Protein Phosphatase 2 Catalytic Subunit Beta	Protein Coding	1
501	PPP2R1A	Protein Phosphatase 2 Scaffold Subunit Aalpha	Protein Coding	1
502	PPP2R1B	Protein Phosphatase 2 Scaffold Subunit Abeta	Protein Coding	1
503	PPP2R2A	Protein Phosphatase 2 Regulatory Subunit Balpha	Protein Coding	1
504	PPP2R2B	Protein Phosphatase 2 Regulatory Subunit Bbeta	Protein Coding	1
505	PPP2R2C	Protein Phosphatase 2 Regulatory Subunit Bgamma	Protein Coding	1
506	PPP2R3A	Protein Phosphatase 2 Regulatory Subunit B''''Alpha	Protein Coding	1
507	PTPA	Protein Phosphatase 2 Phosphatase Activator	Protein Coding	1
508	PPP2R5A	Protein Phosphatase 2 Regulatory Subunit B''Alpha	Protein Coding	1
509	PPP2R5B	Protein Phosphatase 2 Regulatory Subunit B''Beta	Protein Coding	1
510	PPP2R5C	Protein Phosphatase 2 Regulatory Subunit B''Gamma	Protein Coding	1
511	PPP2R5D	Protein Phosphatase 2 Regulatory Subunit B''Delta	Protein Coding	1
512	PPP2R5E	Protein Phosphatase 2 Regulatory Subunit B''Epsilon	Protein Coding	1
513	PPP2R3B	Protein Phosphatase 2 Regulatory Subunit B''''Beta~Name Same As:- HGNC:9310	Protein Coding	1
514	PRKDC	Protein Kinase, DNA-Activated, Catalytic Subunit	Protein Coding	1
515	WNK1	WNK Lysine Deficient Protein Kinase 1	Protein Coding	1
516	PTEN	Phosphatase And Tensin Homolog	Protein Coding	1
517	PXN	Paxillin	Protein Coding	1
518	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
519	RPS6KB1	Ribosomal Protein S6 Kinase B1	Protein Coding	1
520	ATXN1	Ataxin 1	Protein Coding	1
521	ATXN2	Ataxin 2	Protein Coding	1
522	ATXN7	Ataxin 7	Protein Coding	1
523	SLC2A4	Solute Carrier Family 2 Member 4	Protein Coding	1
524	TSC1	TSC Complex Subunit 1	Protein Coding	1
525	TSC2	TSC Complex Subunit 2	Protein Coding	1
526	YAP1	Yes1 Associated Transcriptional Regulator	Protein Coding	1
527	YWHAB	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Beta	Protein Coding	1
528	YWHAE	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon	Protein Coding	1
529	YWHAG	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Gamma	Protein Coding	1
530	YWHAH	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Eta	Protein Coding	1
531	YWHAQ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Theta	Protein Coding	1
532	YWHAZ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta	Protein Coding	1
533	AP2A1	Adaptor Related Protein Complex 2 Subunit Alpha 1	Protein Coding	1
534	ARHGEF7	Rho Guanine Nucleotide Exchange Factor 7	Protein Coding	1
535	ATF2	Activating Transcription Factor 2	Protein Coding	1
536	CASP3	Caspase 3	Protein Coding	1
537	CASP6	Caspase 6	Protein Coding	1
538	CDC25C	Cell Division Cycle 25C	Protein Coding	1
539	CEBPA	CCAAT Enhancer Binding Protein Alpha	Protein Coding	1
540	CEBPG	CCAAT Enhancer Binding Protein Gamma	Protein Coding	1
541	DAXX	Death Domain Associated Protein	Protein Coding	1
542	DDIT3	DNA Damage Inducible Transcript 3	Protein Coding	1
543	ELK1	ETS Transcription Factor ELK1	Protein Coding	1
544	ELK4	ETS Transcription Factor ELK4	Protein Coding	1
545	ETV1	ETS Variant Transcription Factor 1	Protein Coding	1
546	FOSL1	FOS Like 1, AP-1 Transcription Factor Subunit	Protein Coding	1
547	GNAO1	G Protein Subunit Alpha O1	Protein Coding	1
548	GNAT1	G Protein Subunit Alpha Transducin 1	Protein Coding	1
549	GNAT2	G Protein Subunit Alpha Transducin 2	Protein Coding	1
550	GNAZ	G Protein Subunit Alpha Z	Protein Coding	1
551	GNG10	G Protein Subunit Gamma 10	Protein Coding	1
552	GNG11	G Protein Subunit Gamma 11	Protein Coding	1
553	GNG12	G Protein Subunit Gamma 12	Protein Coding	1
554	GNG13	G Protein Subunit Gamma 13	Protein Coding	1
555	GNG5	G Protein Subunit Gamma 5	Protein Coding	1
556	GNG7	G Protein Subunit Gamma 7	Protein Coding	1
557	GNG8	G Protein Subunit Gamma 8	Protein Coding	1
558	GNGT1	G Protein Subunit Gamma Transducin 1	Protein Coding	1
559	GNGT2	G Protein Subunit Gamma Transducin 2	Protein Coding	1
560	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	1
561	HSPB1	Heat Shock Protein Family B (Small) Member 1	Protein Coding	1
562	IL1R2	Interleukin 1 Receptor Type 2	Protein Coding	1
563	IRAK2	Interleukin 1 Receptor Associated Kinase 2	Protein Coding	1
564	IRAK3	Interleukin 1 Receptor Associated Kinase 3	Protein Coding	1
565	IRAK4	Interleukin 1 Receptor Associated Kinase 4	Protein Coding	1
566	JUNB	JunB Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
567	JUND	JunD Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
568	LCK	LCK Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
569	MAP2K3	Mitogen-Activated Protein Kinase Kinase 3	Protein Coding	1
570	MAP2K6	Mitogen-Activated Protein Kinase Kinase 6	Protein Coding	1
571	MAP3K10	Mitogen-Activated Protein Kinase Kinase Kinase 10	Protein Coding	1
572	MAP3K3	Mitogen-Activated Protein Kinase Kinase Kinase 3	Protein Coding	1
573	MAP3K4	Mitogen-Activated Protein Kinase Kinase Kinase 4	Protein Coding	1
574	MAP3K7	Mitogen-Activated Protein Kinase Kinase Kinase 7	Protein Coding	1
575	TAB1	TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 1	Protein Coding	1
576	TAB2	TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 2	Protein Coding	1
577	MAP3K8	Mitogen-Activated Protein Kinase Kinase Kinase 8	Protein Coding	1
578	MAPK11	Mitogen-Activated Protein Kinase 11	Protein Coding	1
579	MAPK12	Mitogen-Activated Protein Kinase 12	Protein Coding	1
580	MAPK13	Mitogen-Activated Protein Kinase 13	Protein Coding	1
581	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
582	MAPK8IP2	Mitogen-Activated Protein Kinase 8 Interacting Protein 2	Protein Coding	1
583	MAPKAPK2	MAPK Activated Protein Kinase 2	Protein Coding	1
584	MAPKAPK3	MAPK Activated Protein Kinase 3	Protein Coding	1
585	MAPKAPK5	MAPK Activated Protein Kinase 5	Protein Coding	1
586	MAX	MYC Associated Transcriptional Regulator X	Protein Coding	1
587	MEF2A	Myocyte Enhancer Factor 2A	Protein Coding	1
588	MEF2C	Myocyte Enhancer Factor 2C	Protein Coding	1
589	MEF2D	Myocyte Enhancer Factor 2D	Protein Coding	1
590	MKNK1	MAPK Interacting Serine/Threonine Kinase 1	Protein Coding	1
591	MKNK2	MAPK Interacting Serine/Threonine Kinase 2	Protein Coding	1
592	PLCB1	Phospholipase C Beta 1	Protein Coding	1
593	PLCB2	Phospholipase C Beta 2	Protein Coding	1
594	PLCB3	Phospholipase C Beta 3	Protein Coding	1
595	PLCB4	Phospholipase C Beta 4	Protein Coding	1
596	PLCD1	Phospholipase C Delta 1	Protein Coding	1
597	PLCD3	Phospholipase C Delta 3	Protein Coding	1
598	PLCD4	Phospholipase C Delta 4	Protein Coding	1
599	PLCE1	Phospholipase C Epsilon 1	Protein Coding	1
600	PLCZ1	Phospholipase C Zeta 1	Protein Coding	1
601	PRKCI	Protein Kinase C Iota	Protein Coding	1
602	PRKD1	Protein Kinase D1	Protein Coding	1
603	PRKD3	Protein Kinase D3	Protein Coding	1
604	PRKCQ	Protein Kinase C Theta	Protein Coding	1
605	PRKCZ	Protein Kinase C Zeta	Protein Coding	1
606	RALA	RAS Like Proto-Oncogene A	Protein Coding	1
607	RALB	RAS Like Proto-Oncogene B	Protein Coding	1
608	RALGDS	Ral Guanine Nucleotide Dissociation Stimulator	Protein Coding	1
609	RIPK1	Receptor Interacting Serine/Threonine Kinase 1	Protein Coding	1
610	RPS6KA5	Ribosomal Protein S6 Kinase A5	Protein Coding	1
611	SOS1	SOS Ras/Rac Guanine Nucleotide Exchange Factor 1	Protein Coding	1
612	SOS2	SOS Ras/Rho Guanine Nucleotide Exchange Factor 2	Protein Coding	1
613	SP1	Sp1 Transcription Factor	Protein Coding	1
614	SPAG9	Sperm Associated Antigen 9	Protein Coding	1
615	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
616	TGFBR1	Transforming Growth Factor Beta Receptor 1	Protein Coding	1
617	TRADD	TNFRSF1A Associated Via Death Domain	Protein Coding	1
618	TRAF2	TNF Receptor Associated Factor 2	Protein Coding	1
619	TRAF6	TNF Receptor Associated Factor 6	Protein Coding	1
620	ZAP70	Zeta Chain Of T Cell Receptor Associated Protein Kinase 70	Protein Coding	1
621	ACTA1	Actin Alpha 1, Skeletal Muscle	Protein Coding	1
622	ACTA2	Actin Alpha 2, Smooth Muscle	Protein Coding	1
623	ACTB	Actin Beta	Protein Coding	1
624	ACTG1	Actin Gamma 1	Protein Coding	1
625	ACTG2	Actin Gamma 2, Smooth Muscle	Protein Coding	1
626	RHOA	Ras Homolog Family Member A	Protein Coding	1
627	RHOB	Ras Homolog Family Member B	Protein Coding	1
628	RHOC	Ras Homolog Family Member C	Protein Coding	1
629	RHOD	Ras Homolog Family Member D	Protein Coding	1
630	RND3	Rho Family GTPase 3	Protein Coding	1
631	RHOG	Ras Homolog Family Member G	Protein Coding	1
632	RHOH	Ras Homolog Family Member H	Protein Coding	1
633	DIRAS3	DIRAS Family GTPase 3	Protein Coding	1
634	RHOJ	Ras Homolog Family Member J	Protein Coding	1
635	RND2	Rho Family GTPase 2	Protein Coding	1
636	RHOQ	Ras Homolog Family Member Q	Protein Coding	1
637	BMX	BMX Non-Receptor Tyrosine Kinase	Protein Coding	1
638	FADD	Fas Associated Via Death Domain	Protein Coding	1
639	FCER1A	Fc Epsilon Receptor Ia	Protein Coding	1
640	FCER1G	Fc Epsilon Receptor Ig	Protein Coding	1
641	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
642	GTF2I	General Transcription Factor IIi	Protein Coding	1
643	ITK	IL2 Inducible T Cell Kinase	Protein Coding	1
644	JAK2	Janus Kinase 2	Protein Coding	1
645	JAK3	Janus Kinase 3	Protein Coding	1
646	LAT	Linker For Activation Of T Cells	Protein Coding	1
647	LCP2	Lymphocyte Cytosolic Protein 2	Protein Coding	1
648	MAPK10	Mitogen-Activated Protein Kinase 10	Protein Coding	1
649	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	1
650	MAPK9	Mitogen-Activated Protein Kinase 9	Protein Coding	1
651	MYD88	MYD88 Innate Immune Signal Transduction Adaptor	Protein Coding	1
652	PAK2	P21 (RAC1) Activated Kinase 2	Protein Coding	1
653	PAK3	P21 (RAC1) Activated Kinase 3	Protein Coding	1
654	PAK4	P21 (RAC1) Activated Kinase 4	Protein Coding	1
655	PAK6	P21 (RAC1) Activated Kinase 6	Protein Coding	1
656	PAK5	P21 (RAC1) Activated Kinase 5	Protein Coding	1
657	RAC2	Rac Family Small GTPase 2	Protein Coding	1
658	RAC3	Rac Family Small GTPase 3	Protein Coding	1
659	STAT2	Signal Transducer And Activator Of Transcription 2	Protein Coding	1
660	STAT3	Signal Transducer And Activator Of Transcription 3	Protein Coding	1
661	STAT4	Signal Transducer And Activator Of Transcription 4	Protein Coding	1
662	STAT5A	Signal Transducer And Activator Of Transcription 5A	Protein Coding	1
663	STAT5B	Signal Transducer And Activator Of Transcription 5B	Protein Coding	1
664	STAT6	Signal Transducer And Activator Of Transcription 6	Protein Coding	1
665	TEC	Tec Protein Tyrosine Kinase	Protein Coding	1
666	TIRAP	TIR Domain Containing Adaptor Protein	Protein Coding	1
667	TLR1	Toll Like Receptor 1	Protein Coding	1
668	TLR10	Toll Like Receptor 10	Protein Coding	1
669	TLR2	Toll Like Receptor 2	Protein Coding	1
670	TLR3	Toll Like Receptor 3	Protein Coding	1
671	TLR4	Toll Like Receptor 4	Protein Coding	1
672	TLR5	Toll Like Receptor 5	Protein Coding	1
673	TLR6	Toll Like Receptor 6	Protein Coding	1
674	TLR7	Toll Like Receptor 7	Protein Coding	1
675	TLR8	Toll Like Receptor 8	Protein Coding	1
676	TLR9	Toll Like Receptor 9	Protein Coding	1
677	TXK	TXK Tyrosine Kinase	Protein Coding	1
678	VAV1	Vav Guanine Nucleotide Exchange Factor 1	Protein Coding	1
679	VAV2	Vav Guanine Nucleotide Exchange Factor 2	Protein Coding	1
680	VAV3	Vav Guanine Nucleotide Exchange Factor 3	Protein Coding	1
681	WAS	WASP Actin Nucleation Promoting Factor	Protein Coding	1

Disorders associated with Akt Signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Human immunodeficiency virus type 1	Enrichment	CCL11, CCL2, CCL3, CCL3L1, CCL5, CCR2, CCR5, CX3CR1, CXCL12, CXCR1, IL10, IL19	16.00
2	Behcet syndrome	Enrichment	CCR1, FAS, IL10, IL12A, IL23R, STAT4, TLR4, TNFRSF1A	7.47
3	Bladder cancer	Enrichment	CDKN1A, EGFR, ERBB2, ERBB3, FGFR3, HRAS, KRAS, PTEN, TP53, TSC1	7.23
4	Il10-related early-onset inflammatory bowel disease	Enrichment	IL10, IL10RA, IL10RB, RIPK1, TGFB1	6.50
5	Noonan syndrome 1	Enrichment	HRAS, KRAS, MRAS, NRAS, RRAS, RRAS2, SOS1, SOS2	6.15
6	Ovarian cancer	Enrichment	AKT1, ALK, AR, BMPR1A, CDKN1B, EGFR, ERBB2, KIT, KRAS, MET, NTRK1, PDGFRA, PTEN, RRAS2, TP53, TSC2	5.93
7	Lung cancer susceptibility 3	Enrichment	EGFR, ERBB2, FGF10, KRAS, ROS1, TP53	5.35
8	Lung cancer	Enrichment	ALK, EGFR, ERBB2, FAS, FASLG, KRAS, MAP3K8, MET	4.94
9	Lung non-small cell carcinoma	Enrichment	EGFR, ERBB2, HRAS, KRAS, NRAS	4.68
10	Lung squamous cell carcinoma	Enrichment	ALK, EGFR, FGFR3, KRAS	4.66
11	Rasopathy	Enrichment	HRAS, KRAS, MRAS, NRAS, RRAS2, SOS1, SOS2	4.61
12	Oligoarticular juvenile idiopathic arthritis	Enrichment	CD247, IL2RA, IL2RB, STAT4	4.59
13	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	CD247, IL2RA, IL2RB, STAT4	4.59
14	Lacrimoauriculodentodigital syndrome 1	Enrichment	FGF10, FGFR2, FGFR3	4.57
15	Breast implant-associated anaplastic large cell lymphoma	Enrichment	JAK1, JAK2, STAT3	4.57
16	T-b+ severe combined immunodeficiency due to cd3delta/cd3epsilon/cd3zeta	Enrichment	CD247, CD3D, CD3E	4.57
17	Nevus, epidermal	Enrichment	FGFR3, HRAS, KRAS, NRAS	4.30
18	Hamartoma	Enrichment	FGFR3, TSC1, TSC2	4.27
19	Squamous cell carcinoma, head and neck	Enrichment	EGFR, PTEN, TNFRSF10B, TP53	4.19
20	Pilomyxoid astrocytoma	Enrichment	FGFR1, KRAS, NTRK2, RAF1	4.19
21	Brachydactyly, type a2	Enrichment	BMP2, BMPR1B, GDF5	3.98
22	Autoimmune lymphoproliferative syndrome	Enrichment	ACTA2, FAS, FASLG	3.98
23	Melanocytic nevus syndrome, congenital	Enrichment	ALK, HRAS, NRAS, RAF1	3.90
24	Severe combined immunodeficiency	Enrichment	CD247, CD3D, CD3E, CD3G, IL7R, LCK, ZAP70	3.89
25	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS, KRAS, NRAS	3.77
26	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	AKT3, CCND2, PIK3R2	3.68
27	Focal cortical dysplasia, type ii	Enrichment	MTOR, TSC1, TSC2	3.68
28	Isolated focal cortical dysplasia type ii	Enrichment	MTOR, TSC1, TSC2	3.68
29	Glioma	Enrichment	FGFR2, NTRK3, PTEN	3.68
30	Adult hepatocellular carcinoma	Enrichment	EGF, TP53, TSC1, TSC2	3.66
31	Myeloma, multiple	Enrichment	CCND1, FGFR3, FLT3, IL7R, KRAS, MST1R, PIK3R2, TP53, YAP1	3.63
32	Giant cell glioblastoma	Enrichment	EGFR, FGFR1, FGFR3, ROS1, TP53	3.63
33	Primary hypereosinophilic syndrome	Enrichment	FGFR1, PDGFRA, PDGFRB	3.59
34	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	CEBPA, FLT3, KIT	3.38
35	Colorectal cancer	Enrichment	AKT1, BAX, CCND1, ERBB2, FGFR2, FGFR3, IGF2, MET, NRAS, PIK3R1, TP53	3.37
36	Differentiated thyroid carcinoma	Enrichment	ALK, HRAS, KRAS, NRAS, NTRK1, NTRK3	3.35
37	Chronic mucocutaneous candidiasis	Enrichment	IL17RA, IL17RC, STAT1	3.30
38	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	ITGA2, ITGA2B, ITGB3	3.30
39	Hemimegalencephaly	Enrichment	AKT3, MTOR, PTEN	3.29
40	Lip and oral cavity carcinoma	Enrichment	EGFR, HRAS, KIT, TP53	3.21
41	Testicular germ cell tumor	Enrichment	FGFR3, KIT, KITLG	3.09
42	Inflammatory bowel disease 25, autosomal recessive	Enrichment	IL10RB, RIPK1, TGFB1	3.09
43	Pfeiffer syndrome	Enrichment	FGFR1, FGFR2	3.05
44	Jackson-weiss syndrome	Enrichment	FGFR1, FGFR2	3.05
45	Fibrodysplasia ossificans progressiva	Enrichment	ACVR1, BMPR2	3.05
46	Loeys-dietz syndrome 4	Enrichment	TGFB2, TGFB3	3.05
47	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB, ACTG1	3.05
48	Systemic lupus erythematosus	Enrichment	IL10, IRAK1, ITGAM, STAT4, TLR7, TNF	3.01
49	Breast adenocarcinoma	Enrichment	AKT1, KRAS, TP53	3.00
50	Childhood absence epilepsy	Enrichment	GABRA1, GABRB3, GABRG2	3.00
51	Microform holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1	2.97
52	Lobar holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1	2.97
53	Lymphatic malformation 1	Enrichment	EPHB4, FLT4	2.90
54	Intracranial hypertension, idiopathic	Enrichment	EPHB4, FLT4	2.90
55	Cervical cancer	Enrichment	FGFR3, TP53	2.90
56	Encephalocraniocutaneous lipomatosis	Enrichment	FGFR1, KRAS	2.90
57	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS, NRAS	2.90
58	Angioma, tufted	Enrichment	GNA14, KDR	2.90
59	Cervix carcinoma	Enrichment	FGFR3, TP53	2.90
60	Hereditary lymphedema i	Enrichment	EPHB4, FLT4	2.90
61	Noonan syndrome 3	Enrichment	HRAS, KRAS, SOS1	2.86
62	Common variable immunodeficiency	Enrichment	CD40LG, NFKB1, TNFRSF13B	2.86
63	Lymphangioleiomyomatosis	Enrichment	TSC1, TSC2	2.84
64	Juvenile polyposis of infancy	Enrichment	BMPR1A, PTEN	2.84
65	Noonan syndrome and noonan-related syndrome	Enrichment	HRAS, KRAS, NRAS, SOS1	2.81
66	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS, NRAS, PTEN	2.77
67	Follicular thyroid carcinoma	Enrichment	HRAS, NRAS, PTEN	2.77
68	Semilobar holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1	2.76
69	Normosmic congenital hypogonadotropic hypogonadism	Enrichment	FGF17, FGF8, FGFR1, GNRH1	2.76
70	Gliosarcoma	Enrichment	EGFR, FGFR1, FGFR3, TP53	2.70
71	Rhabdomyosarcoma	Enrichment	ALK, HRAS, PTEN, TP53	2.59
72	Leukemia, acute myeloid	Enrichment	CEBPA, FLT3, KIT, KRAS, NRAS, TP53	2.58
73	Brachydactyly, type a1	Enrichment	BMPR1B, GDF5	2.58
74	Crouzon syndrome	Enrichment	FGFR2, FGFR3	2.58
75	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	ITGB3, STAT3	2.58
76	Brachydactyly, type c	Enrichment	BMPR1B, GDF5	2.58
77	Bleeding disorder, platelet-type, 16	Enrichment	ITGA2B, ITGB3	2.58
78	Acromesomelic dysplasia 2a	Enrichment	BMPR1B, GDF5	2.58
79	Acromesomelic dysplasia 2c	Enrichment	BMPR1B, GDF5	2.58
80	Acromesomelic dysplasia 2b	Enrichment	BMPR1B, GDF5	2.58
81	Mycosis fungoides	Enrichment	CD28, TNFRSF1B	2.58
82	Immunodeficiency 98 with autoinflammation, x-linked	Enrichment	FASLG, TLR8	2.58
83	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	GNA11, PIK3R1	2.58
84	Anastomosing haemangioma	Enrichment	GNA11, GNA14	2.58
85	Saczary syndrome	Enrichment	CD28, TNFRSF1B	2.58
86	Loeys-dietz syndrome	Enrichment	TGFB2, TGFB3, TGFBR1	2.50
87	Arteriovenous malformation	Enrichment	EPHB4, HRAS, TEK	2.50
88	Psoriatic arthritis	Enrichment	LTA, TNF	2.44
89	Large congenital melanocytic nevus	Enrichment	HRAS, NRAS	2.44
90	Testicular germ cell cancer	Enrichment	FGFR3, KIT	2.44
91	Spermatocytoma	Enrichment	FGFR3, HRAS	2.44
92	Asthma	Enrichment	CCL11, IL13, TNF	2.44
93	Heritable pulmonary arterial hypertension	Enrichment	ACVRL1, BMPR2, GDF2	2.44
94	Arteriovenous malformations of the brain	Enrichment	EGFR, IL6, KRAS, TIMP3	2.41
95	Tuberous sclerosis 1	Enrichment	TSC1, TSC2	2.38
96	Laryngeal squamous cell carcinoma	Enrichment	PTEN, TNFRSF10B	2.38
97	Non-immune hydrops fetalis	Enrichment	ANGPT2, EPHB4, FLT4, HRAS, KRAS	2.37
98	Marfan syndrome	Enrichment	LTBP2, TGFB2, TGFBR1	2.36
99	Myopathy, x-linked, with excessive autophagy	Enrichment	EPHB4, HRAS, TEK	2.36
100	Kallmann syndrome	Enrichment	FGF17, FGF8, FGFR1, SEMA3A	2.35
101	Type 2 diabetes mellitus	Enrichment	AKT2, IL6, INSR, IRS1, MAPK8IP1, SLC2A4	2.33
102	Undetermined early-onset epileptic encephalopathy	Enrichment	FGF12, GABRA2, GABRA5, GABRB2, GABRG2, NTRK2, YWHAG	2.30
103	Diffuse large b-cell lymphoma	Enrichment	BTK, FOXO1, PTEN, TP53	2.30
104	Erythrocytosis, familial, 1	Enrichment	EPOR, JAK2	2.29
105	Glaucoma 3, primary infantile, b	Enrichment	LTBP2, TEK	2.29
106	Saethre-chotzen syndrome	Enrichment	FGFR2, FGFR3	2.29
107	Multiple synostoses syndrome	Enrichment	GDF5, GDF6	2.29
108	Pediatric systemic lupus erythematosus	Enrichment	IRAK1, STAT4	2.29
109	Gastric cancer	Enrichment	ERBB2, FGFR2, IL1B, KRAS, PTEN, TP53	2.27
110	Combined immunodeficiency	Enrichment	CD27, IL2RG, ZAP70	2.23
111	Combined t cell and b cell immunodeficiency	Enrichment	CD27, IL2RG, ZAP70	2.23
112	Combined t and b cell immunodeficiency	Enrichment	CD27, IL2RG, ZAP70	2.23
113	Pulmonary hypertension, primary, 1	Enrichment	ACVRL1, BMPR2, GDF2	2.22
114	Nk-cell enteropathy	Enrichment	ERBB4, IGF1R, JAK3	2.22
115	Glycogen storage disease	Enrichment	GYS1, GYS2, PFKM	2.15
116	Auriculocondylar syndrome 1	Enrichment	GNAI3, PLCB4	2.15
117	Achromatopsia 4	Enrichment	GNAI3, GNAT2	2.15
118	Lung sarcomatoid carcinoma	Enrichment	KRAS, TP53	2.15
119	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	KRAS, NRAS	2.15
120	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	FLT3, KIT	2.15
121	Juvenile myelomonocytic leukemia	Enrichment	KRAS, NRAS, RRAS	2.12
122	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	AKT3, PIK3R2	2.09
123	Lymphoproliferative syndrome 2	Enrichment	CD27, XIAP	2.09
124	Tuberous sclerosis	Enrichment	TSC1, TSC2	2.09
125	Hemifacial hyperplasia	Enrichment	FGFR2, FGFR3	2.07
126	Insulin-like growth factor i	Enrichment	IGF1, IGF1R	2.07
127	Ventricular septal defect 1	Enrichment	BMP2, BMP7	2.07
128	Holoprosencephaly	Enrichment	FGF8, FGFR1	2.07
129	Diffuse cutaneous systemic sclerosis	Enrichment	CCN2, CCR6	2.07
130	Hereditary pulmonary alveolar proteinosis	Enrichment	CSF2RA, CSF2RB	2.07
131	Meningioma	Enrichment	AKT1, PDGFB, PTEN	2.04
132	Septopreoptic holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1	2.03
133	Midline interhemispheric variant of holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1	2.03
134	Inherited cancer-predisposing syndrome	Enrichment	ALK, BMPR1A, CDKN1B, EGFR, KIT, MET, PDGFRA, PTEN, TP53, TSC1, TSC2	1.93
135	Acute myeloid leukemia with maturation	Enrichment	FLT3, KIT	1.93
136	Atrial septal defect 1	Enrichment	BMP2, TGFB2	1.91
137	Hemihyperplasia, isolated	Enrichment	IGF2, RHOA	1.91
138	Holoprosencephaly 1	Enrichment	FGF8, FGFR1	1.91
139	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	ITGA6, ITGB4	1.91
140	Limited scleroderma	Enrichment	CCN2, CCR6	1.91
141	46,xy disorder of sex development	Enrichment	FGFR3, INSR	1.91
142	Alobar holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1	1.88
143	Rhabdomyosarcoma 2	Enrichment	FOXO1, TP53	1.88
144	Pre-eclampsia	Enrichment	FLT1, NOS3	1.88
145	Acute megakaryocytic leukemia	Enrichment	PTEN, TP53	1.88
146	Thrombocytopenia	Enrichment	ACVRL1, ITGA2B, ITGB3, THPO, WAS	1.86
147	Generalized epilepsy with febrile seizures plus	Enrichment	FGF13, GABRD, GABRG2	1.84
148	Glaucoma 3, primary congenital, a	Enrichment	LTBP2, TEK	1.77
149	Glanzmann thrombasthenia 1	Enrichment	ITGA2B, ITGB3	1.77
150	Neuropathy, hereditary sensory and autonomic, type v	Enrichment	NGF, NTRK1	1.77
151	Essential thrombocythemia	Enrichment	JAK2, THPO	1.77
152	Hereditary hemorrhagic telangiectasia	Enrichment	ACVRL1, GDF2	1.77
153	Melanoma, uveal	Enrichment	GNA11, PLCB4	1.77
154	Hemangioma, capillary infantile	Enrichment	FLT4, KDR	1.77
155	Li-fraumeni syndrome	Enrichment	MDM2, TP53	1.71
156	Cowden syndrome 1	Enrichment	EGFR, PTEN	1.71
157	Craniosynostosis	Enrichment	FGFR2, FGFR3, IL11RA	1.68
158	Basal ganglia calcification, idiopathic, 1	Enrichment	PDGFB, PDGFRB	1.65
159	Hemochromatosis, type 1	Enrichment	BMP2, BMP6	1.65
160	Prostate cancer	Enrichment	AR, EPHB2, PTEN, TP53	1.64
161	Breast cancer	Enrichment	AKT1, GNG3, IL2, IL7R, KRAS, PTEN, TP53	1.63
162	Gastrointestinal stromal tumor	Enrichment	KIT, PDGFRA	1.63
163	Capillary malformation-arteriovenous malformation 1	Enrichment	EPHB4, KRAS	1.63
164	Leukemia, chronic myeloid	Enrichment	KRAS, NRAS	1.63
165	Gallbladder cancer	Enrichment	KRAS, TP53	1.63
166	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	FLT3, TP53	1.63
167	Multiple endocrine neoplasia, type i	Enrichment	CDKN1A, CDKN1B	1.58
168	Renal cell carcinoma, papillary, 1	Enrichment	MET, MTOR	1.58
169	Overgrowth syndrome	Enrichment	MTOR, PIK3R1	1.58
170	Rheumatoid arthritis	Enrichment	IL10, TLR1	1.55
171	Junctional epidermolysis bullosa	Enrichment	ITGA6, ITGB4	1.55
172	Primary biliary cholangitis	Enrichment	IL12A, IL12RB1	1.55
173	Renal agenesis, bilateral	Enrichment	FGF20, ITGA8	1.55
174	Amyloidosis, primary localized cutaneous, 1	Enrichment	OSMR	1.52
175	Periodic fever, familial, autosomal dominant	Enrichment	TNFRSF1A	1.52
176	Erythroleukemia, familial	Enrichment	ERBB3	1.52
177	Hypochondroplasia	Enrichment	FGFR3	1.52
178	Beare-stevenson cutis gyrata syndrome	Enrichment	FGFR2	1.52
179	Paget disease, extramammary	Enrichment	ERBB2	1.52
180	Immune deficiency, familial variable	Enrichment	TNFRSF13B	1.52
181	Hypocalciuric hypercalcemia, familial, type ii	Enrichment	GNA11	1.52
182	Osteoglophonic dysplasia	Enrichment	FGFR1	1.52
183	Thanatophoric dysplasia, type i	Enrichment	FGFR3	1.52
184	Microspherophakia and/or megalocornea, with ectopia lentis and with or without secondary glaucoma	Enrichment	LTBP2	1.52
185	Leprosy 3	Enrichment	TLR2	1.52
186	Trigonocephaly 1	Enrichment	FGFR1	1.52
187	Donohue syndrome	Enrichment	INSR	1.52
188	Spinocerebellar ataxia 27a	Enrichment	FGF14	1.52
189	Baraitser-winter syndrome 1	Enrichment	ACTB	1.52
190	Muenke syndrome	Enrichment	FGFR3	1.52
191	Thrombocytopenia 1	Enrichment	WAS	1.52
192	Intellectual developmental disorder, x-linked 30	Enrichment	PAK3	1.52
193	Premature aging syndrome, penttinen type	Enrichment	PDGFRB	1.52
194	Surfactant metabolism dysfunction, pulmonary, 4	Enrichment	CSF2RA	1.52
195	Type 1 diabetes mellitus 10	Enrichment	IL2RA	1.52
196	Systemic lupus erythematosus 6	Enrichment	ITGAM	1.52
197	Hyperinsulinemic hypoglycemia, familial, 5	Enrichment	INSR	1.52
198	Legionnaire disease	Enrichment	TLR5	1.52
199	Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities	Enrichment	INSR	1.52
200	Telangiectasia, hereditary hemorrhagic, type 2	Enrichment	ACVRL1	1.52
201	Hypomagnesemia 4, renal	Enrichment	EGF	1.52
202	Immunodeficiency 68	Enrichment	MYD88	1.52
203	Osteopetrosis, autosomal recessive 7	Enrichment	TNFRSF11A	1.52
204	Glaucoma 3, primary congenital, d	Enrichment	LTBP2	1.52
205	Diabetes mellitus, insulin-resistant, with acanthosis nigricans	Enrichment	INSR	1.52
206	Microphthalmia, isolated 4	Enrichment	GDF6	1.52
207	Angel-shaped phalangoepiphyseal dysplasia	Enrichment	GDF5	1.52
208	Pseudohypoparathyroidism, type ic	Enrichment	GNAS	1.52
209	Hypereosinophilic syndrome, idiopathic	Enrichment	PDGFRA	1.52
210	Immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis	Enrichment	RAC2	1.52
211	Deafness, autosomal recessive 39	Enrichment	HGF	1.52
212	Scaphocephaly, maxillary retrusion, and impaired intellectual development	Enrichment	FGFR2	1.52
213	Polyposis syndrome, hereditary mixed, 2	Enrichment	BMPR1A	1.52
214	Acromesomelic dysplasia 3	Enrichment	BMPR1B	1.52
215	Macroglobulinemia, waldenstrom 1	Enrichment	MYD88	1.52
216	Congenital myopathy 2a, typical, autosomal dominant	Enrichment	ACTA1	1.52
217	Immunodeficiency 30	Enrichment	IL12RB1	1.52
218	Osseous heteroplasia, progressive	Enrichment	GNAS	1.52
219	Apert syndrome	Enrichment	FGFR2	1.52
220	Basal ganglia calcification, idiopathic, 5	Enrichment	PDGFB	1.52
221	Hyperpigmentation with or without hypopigmentation, familial progressive	Enrichment	KITLG	1.52
222	Immunodeficiency 83 viral infections	Enrichment	TLR3	1.52
223	Immunodeficiency 16	Enrichment	TNFRSF4	1.52
224	Polycystic lung disease	Enrichment	CCR2	1.52
225	Myofibromatosis, infantile, 1	Enrichment	PDGFRB	1.52
226	Bacteremia 1	Enrichment	TIRAP	1.52
227	Thanatophoric dysplasia, type ii	Enrichment	FGFR3	1.52
228	Myopathy, scapulohumeroperoneal	Enrichment	ACTA1	1.52
229	Lethal congenital contracture syndrome 2	Enrichment	ERBB3	1.52
230	Leprosy 5	Enrichment	TLR1	1.52
231	Hypogonadotropic hypogonadism 20 with or without anosmia	Enrichment	FGF17	1.52
232	Ciliary dyskinesia, primary, 33	Enrichment	DRC4	1.52
233	Brachydactyly, type a1, d	Enrichment	BMPR1B	1.52
234	Gist-plus syndrome	Enrichment	PDGFRA	1.52
235	Camptodactyly, tall stature, and hearing loss syndrome	Enrichment	FGFR3	1.52
236	Whim syndrome 1	Enrichment	CXCR4	1.52
237	Ataxia-oculomotor apraxia 3	Enrichment	PIK3R5	1.52
238	Transient erythroblastopenia of childhood	Enrichment	TEC	1.52
239	Hypogonadotropic hypogonadism 23 with or without anosmia	Enrichment	LHB	1.52
240	Aplasia of lacrimal and salivary glands	Enrichment	FGF10	1.52
241	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	1.52
242	Bent bone dysplasia syndrome 1	Enrichment	FGFR2	1.52
243	Weill-marchesani syndrome 3	Enrichment	LTBP2	1.52
244	Craniosynostosis and dental anomalies	Enrichment	IL11RA	1.52
245	Acth-independent macronodular adrenal hyperplasia 1	Enrichment	GNAS	1.52
246	Angioedema, hereditary, 5	Enrichment	ANGPT1	1.52
247	Megacystis-microcolon-intestinal hypoperistalsis syndrome 5	Enrichment	ACTG2	1.52
248	Visceral neuropathy, familial, 2, autosomal recessive	Enrichment	ERBB2	1.52
249	Neurodevelopmental disorder with hypotonia and dysmorphic facies	Enrichment	GNB2	1.52
250	Pseudo-torch syndrome 3	Enrichment	STAT2	1.52
251	Growth hormone insensitivity syndrome with immune dysregulation 2, autosomal dominant	Enrichment	STAT5B	1.52
252	Immunodeficiency 81	Enrichment	LCP2	1.52
253	Immunodeficiency 82 with systemic inflammation	Enrichment	SYK	1.52
254	Developmental and epileptic encephalopathy 58	Enrichment	NTRK2	1.52
255	Multiple synostoses syndrome 4	Enrichment	GDF6	1.52
256	Hyper-ige syndrome 6, autosomal dominant, with recurrent infections	Enrichment	STAT6	1.52
257	Intellectual developmental disorder, x-linked 110	Enrichment	FGF13	1.52
258	Pituitary adenoma 3, multiple types	Enrichment	GNAS	1.52
259	Immunodeficiency 130 with hpv-related verrucosis	Enrichment	IL7	1.52
260	Spinocerebellar ataxia 27b, late-onset	Enrichment	FGF14	1.52
261	Venous malformations, multiple cutaneous and mucosal	Enrichment	TEK	1.52
262	Knobloch syndrome 2	Enrichment	PAK2	1.52
263	Immunodeficiency 63 with lymphoproliferation and autoimmunity	Enrichment	IL2RB	1.52
264	Neurodevelopmental disorder with structural brain anomalies and dysmorphic facies	Enrichment	RAC3	1.52
265	Hyperemesis gravidarum	Enrichment	GDF15	1.52
266	Disabling pansclerotic morphea of childhood	Enrichment	STAT4	1.52
267	Amegakaryocytic thrombocytopenia, congenital, 2	Enrichment	THPO	1.52
268	Deafness, autosomal recessive 125	Enrichment	GAS2	1.52
269	Short syndrome	Enrichment	PIK3R1	1.52
270	Immunodeficiency 74, covid19-related, x-linked	Enrichment	TLR7	1.52
271	Intellectual developmental disorder with macrocephaly, seizures, and speech delay	Enrichment	PAK1	1.52
272	Fetomaternal alloimmune thrombocytopenia 2	Enrichment	ITGA2B	1.52
273	Ovarian dysgenesis 2	Enrichment	BMP15	1.52
274	Hereditary lymphedema id	Enrichment	VEGFC	1.52
275	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	1.52
276	Okt4 epitope deficiency	Enrichment	CD4	1.52
277	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	1.52
278	Systemic lupus erythematosus 1	Enrichment	TLR5	1.52
279	Osteofibrous dysplasia	Enrichment	MET	1.52
280	Graft-versus-host disease	Enrichment	IL10	1.52
281	X-linked immunodeficiency 74	Enrichment	TLR7	1.52
282	Microphthalmia, syndromic 6	Enrichment	BMP4	1.52
283	Isolated growth hormone deficiency type iii	Enrichment	BTK	1.52
284	Myeloid and lymphoid neoplasms associated with pdgfra rearrangement	Enrichment	PDGFRA	1.52
285	Systemic lupus erythematosus 17	Enrichment	TLR7	1.52
286	Immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia	Enrichment	RAC2	1.52
287	Developmental and epileptic encephalopathy 90	Enrichment	FGF13	1.52
288	Orofacial cleft 11	Enrichment	BMP4	1.52
289	T-cell large granular lymphocyte leukemia	Enrichment	STAT3	1.52
290	Metacarpal 4-5 fusion	Enrichment	FGF16	1.52
291	Immunodeficiency 18	Enrichment	CD3E	1.52
292	Systemic lupus erythematosus 11	Enrichment	STAT4	1.52
293	Lymphatic malformation 4	Enrichment	VEGFC	1.52
294	Chronic recurrent multifocal osteomyelitis 3	Enrichment	IL1R1	1.52
295	Allergic rhinitis	Enrichment	IL13	1.52
296	Lacrimoauriculodentodigital syndrome 3	Enrichment	FGF10	1.52
297	Familial isolated trichomegaly	Enrichment	FGF5	1.52
298	Immunoglobulin a deficiency 2	Enrichment	TNFRSF13B	1.52
299	Deafness, autosomal recessive 97	Enrichment	MET	1.52
300	Immunodeficiency 25	Enrichment	CD247	1.52
301	Skin/hair/eye pigmentation, variation in, 7	Enrichment	KITLG	1.52
302	Psoriasis 7	Enrichment	IL23R	1.52
303	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	1.52
304	Crouzon syndrome with acanthosis nigricans	Enrichment	FGFR3	1.52
305	Camurati-engelmann disease 2	Enrichment	TGFB2	1.52
306	Geleophysic dysplasia 3	Enrichment	LTBP3	1.52
307	Spinocerebellar ataxia 14	Enrichment	PRKCG	1.52
308	Immunodeficiency with hyper-igm, type 3	Enrichment	CD40	1.52
309	Lymphoproliferative syndrome 1	Enrichment	ITK	1.52
310	Becker nevus syndrome	Enrichment	ACTB	1.52
311	Dystonia-deafness syndrome 1	Enrichment	ACTB	1.52
312	Autism 9	Enrichment	MET	1.52
313	Visceral neuropathy, familial, 3, autosomal dominant	Enrichment	ACTG2	1.52
314	Glaucoma 1, open angle, o	Enrichment	NTF4	1.52
315	Interleukin 6, serum level of, quantitative trait locus	Enrichment	IL6R	1.52
316	Iron overload	Enrichment	BMP6	1.52
317	Surfactant metabolism dysfunction, pulmonary, 5	Enrichment	CSF2RB	1.52
318	Immunodeficiency 31a	Enrichment	STAT1	1.52
319	Congenital myopathy 2b, severe infantile, autosomal recessive	Enrichment	ACTA1	1.52
320	Basal ganglia calcification, idiopathic, 4	Enrichment	PDGFRB	1.52
321	Soluble interleukin-6 receptor, serum level of, quantitative trait locus	Enrichment	IL6R	1.52
322	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	1.52
323	Hypogonadotropic hypogonadism 12 with or without anosmia	Enrichment	GNRH1	1.52
324	Multiple sclerosis 5	Enrichment	TNFRSF1A	1.52
325	Immunodeficiency 90 with encephalopathy, functional hyposplenia, and hepatic dysfunction	Enrichment	FADD	1.52
326	Autoinflammation, antibody deficiency, and immune dysregulation	Enrichment	PLCG2	1.52
327	Immunodeficiency 29	Enrichment	IL12B	1.52
328	Hypogonadotropic hypogonadism 16 with or without anosmia	Enrichment	SEMA3A	1.52
329	Leber congenital amaurosis 17	Enrichment	GDF6	1.52
330	Hypocalcemia, autosomal dominant 2	Enrichment	GNA11	1.52
331	Telangiectasia, hereditary hemorrhagic, type 5	Enrichment	GDF2	1.52
332	Amyotrophic lateral sclerosis 19	Enrichment	ERBB4	1.52
333	Hereditary thrombocytosis with transverse limb defect	Enrichment	THPO	1.52
334	Hyper-ige syndrome 5, autosomal recessive, with recurrent infections	Enrichment	IL6R	1.52
335	Melioidosis	Enrichment	TLR5	1.52
336	Candidiasis, familial, 9	Enrichment	IL17RC	1.52
337	Myeloid and lymphoid neoplasms associated with pdgfrb rearrangement	Enrichment	PDGFRB	1.52
338	Charcot-marie-tooth disease, dominant intermediate f	Enrichment	GNB4	1.52
339	Autosomal dominant familial visceral neuropathy	Enrichment	ACTG2	1.52
340	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	1.52
341	Inflammatory bowel disease 17	Enrichment	IL23R	1.52
342	Macular degeneration, age-related, 10	Enrichment	TLR4	1.52
343	Immunodeficiency 31b	Enrichment	STAT1	1.52
344	Type 1 diabetes mellitus 22	Enrichment	CCR5	1.52
345	Immunodeficiency 123 with hpv-related verrucosis	Enrichment	CD28	1.52
346	Hypogonadotropic hypogonadism 6 with or without anosmia	Enrichment	FGF8	1.52
347	Obesity, hyperphagia, and developmental delay	Enrichment	NTRK2	1.52
348	Disorders of gnas inactivation	Enrichment	GNAS	1.52
349	Macular degeneration, age-related, 12	Enrichment	CX3CR1	1.52
350	Achondroplasia, severe, with developmental delay and acanthosis nigricans	Enrichment	FGFR3	1.52
351	Kosaki overgrowth syndrome	Enrichment	PDGFRB	1.52
352	Familial cold autoinflammatory syndrome 3	Enrichment	PLCG2	1.52
353	Tumoral calcinosis, hyperphosphatemic, familial, 2	Enrichment	FGF23	1.52
354	Hartsfield syndrome	Enrichment	FGFR1	1.52
355	Loeys-dietz syndrome 5	Enrichment	TGFB3	1.52
356	Renal hypodysplasia/aplasia 2	Enrichment	FGF20	1.52
357	Autoimmune disease, multisystem, infantile-onset, 1	Enrichment	STAT3	1.52
358	Psoriasis	Enrichment	IL17RA	1.52
359	Tnf receptor-associated periodic fever syndrome	Enrichment	TNFRSF1A	1.52
360	20p12.3 microdeletion syndrome	Enrichment	BMP2	1.52
361	Cutis laxa, autosomal recessive, type iie	Enrichment	LTBP1	1.52
362	Was-related disorders	Enrichment	WAS	1.52
363	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	1.52
364	Takenouchi-kosaki syndrome	Enrichment	CDC42	1.52
365	Intellectual developmental disorder, autosomal dominant 42	Enrichment	GNB1	1.52
366	Glaucoma 3, primary congenital, e	Enrichment	TEK	1.52
367	Congenital myopathy 2c, severe infantile, autosomal dominant	Enrichment	ACTA1	1.52
368	Short stature, facial dysmorphism, and skeletal anomalies with or without cardiac anomalies 1	Enrichment	BMP2	1.52
369	Sick sinus syndrome 4	Enrichment	GNB2	1.52
370	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	1.52
371	Brain abnormalities, neurodegeneration, and dysosteosclerosis	Enrichment	CSF1R	1.52
372	Developmental and epileptic encephalopathy 47	Enrichment	FGF12	1.52
373	Ocular pterygium-digital keloid dysplasia syndrome	Enrichment	PDGFRB	1.52
374	Immunodeficiency 79	Enrichment	CD4	1.52
375	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	1.52
376	Immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia	Enrichment	RAC2	1.52
377	Premature ovarian failure 14	Enrichment	GDF9	1.52
378	Telangiectasis	Enrichment	ACVRL1	1.52
379	Immunodeficiency 129	Enrichment	RHOH	1.52
380	Whim syndrome 2	Enrichment	CXCR2	1.52
381	Deafness, autosomal dominant 69	Enrichment	KITLG	1.52
382	Immunodeficiency 19, severe combined	Enrichment	CD3D	1.52
383	Immature teratoma of ovary	Enrichment	BMP15	1.52
384	T-b+ severe combined immunodeficiency due to jak3 deficiency	Enrichment	JAK3	1.52
385	Thrombocytopenia 9	Enrichment	THPO	1.52
386	Arthrogryposis, distal, type 11	Enrichment	MET	1.52
387	Amelogenesis imperfecta, type ih	Enrichment	ITGB6	1.52
388	Lacrimoauriculodentodigital syndrome 2	Enrichment	FGFR3	1.52
389	Baraitser-winter syndrome	Enrichment	ACTB	1.52
390	Csf1r-related disorder	Enrichment	CSF1R	1.52
391	Immunodeficiency 109 with lymphoproliferation	Enrichment	TNFRSF9	1.52
392	Short-rib thoracic dysplasia 22 without polydactyly	Enrichment	FGF4	1.52
393	Bockenheimer syndrome	Enrichment	TEK	1.52
394	T-cell immunodeficiency with epidermodysplasia verruciformis	Enrichment	RHOH	1.52
395	Glaucoma secondary to spherophakia/ectopia lentis and megalocornea	Enrichment	LTBP2	1.52
396	Colitis	Enrichment	SYK	1.52
397	Stat3-related early-onset multisystem autoimmune disease	Enrichment	STAT3	1.52
398	Primary pulmonary hypertension	Enrichment	BMPR2	1.52
399	Fetomaternal alloimmune thrombocytopenia 3	Enrichment	ITGA2	1.52
400	Pulmonary hypertension	Enrichment	BMPR2	1.52
401	Immune dysregulation, neurodevelopmental defects, and colitis	Enrichment	ITGAV	1.52
402	Zebra body myopathy	Enrichment	ACTA1	1.52
403	Spinocerebellar ataxia type 27b	Enrichment	FGF14	1.52
404	Infantile lad-like disease due to rac2 deficiency	Enrichment	RAC2	1.52
405	Fgfr3-related chondrodysplasia	Enrichment	FGFR3	1.52
406	Chronic neutrophilic leukemia	Enrichment	CSF3R	1.52
407	Congenital smooth muscle hamartoma	Enrichment	ACTB	1.52
408	Drug- or toxin-induced pulmonary arterial hypertension	Enrichment	BMPR2	1.52
409	Waldenstram macroglobulinemia	Enrichment	MYD88	1.52
410	Common variable immunodeficiency phenotype due to homozygous taci deficiency	Enrichment	TNFRSF13B	1.52
411	Reticular dysgenesis-like severe combined immunodeficiency	Enrichment	RAC2	1.52
412	Nocarh syndrome	Enrichment	CDC42	1.52
413	Autosomal recessive severe congenital neutropenia due to cxcr2 deficiency	Enrichment	CXCR2	1.52
414	Congenital primary lymphedema of gordon	Enrichment	VEGFC	1.52
415	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	1.52
416	Camptodactyly-tall stature-scoliosis-hearing loss syndrome	Enrichment	FGFR3	1.52
417	Immunodeficiency 19	Enrichment	CD3D	1.52
418	Familial progressive hyperpigmentation	Enrichment	KITLG	1.52
419	Early-onset calcifying leukoencephalopathy-skeletal dysplasia	Enrichment	CSF1R	1.52
420	Monostotic fibrous dysplasia	Enrichment	GNAS	1.52
421	T-b+ severe combined immunodeficiency due to il-7ralpha deficiency	Enrichment	IL7R	1.52
422	Actin-accumulation myopathy	Enrichment	ACTA1	1.52
423	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	1.52
424	Phakomatosis cesiomarmorata	Enrichment	GNA11	1.52
425	Common variable immunodeficiency phenotype due to tweak deficiency	Enrichment	TNFSF12	1.52
426	Hartsfield-bixler-demyer syndrome	Enrichment	FGFR1	1.52
427	Kaposiform hemangioendothelioma	Enrichment	GNA14	1.52
428	Chronic lymphoproliferative disorder of natural killer cells	Enrichment	STAT3	1.52
429	Mazabraud syndrome	Enrichment	GNAS	1.52
430	Mendelian susceptibility to mycobacterial diseases due to partial jak1 deficiency	Enrichment	JAK1	1.52
431	Myopathic intestinal pseudoobstruction	Enrichment	ACTG2	1.52
432	Rac2-related combined immunodeficiency-bronchiectasis-cancer-predisposing syndrome	Enrichment	RAC2	1.52
433	Egf-related primary hypomagnesemia with intellectual disability	Enrichment	EGF	1.52
434	Non-syndromic unicoronal craniosynostosis	Enrichment	FGFR2	1.52
435	Familial progressive hyper- and hypopigmentation	Enrichment	KITLG	1.52
436	Interstitial lung disease specific to childhood	Enrichment	FGF10	1.52
437	Serous carcinoma of the corpus uteri	Enrichment	ERBB2	1.52
438	Actg2 visceral myopathy	Enrichment	ACTG2	1.52
439	Glioma susceptibility 1	Enrichment	ERBB2, TP53	1.52
440	Omenn syndrome	Enrichment	IL2RG, IL7R	1.46
441	Autosomal dominant macrothrombocytopenia	Enrichment	ITGA2B, ITGB3	1.46
442	Lennox-gastaut syndrome	Enrichment	GABRB3, GABRG2	1.46
443	Lymphatic malformation 5	Enrichment	EPHB4	1.45
444	Brachydactyly, type b1	Enrichment	ROR2	1.45
445	Cardiospondylocarpofacial syndrome	Enrichment	MAP3K7	1.45
446	Oculoectodermal syndrome	Enrichment	KRAS	1.45
447	Noonan syndrome 4	Enrichment	SOS1	1.45
448	Leprosy 4	Enrichment	LTA	1.45
449	Mastocytosis, cutaneous	Enrichment	KIT	1.45
450	Neuroblastoma 3	Enrichment	ALK	1.45
451	Nail disorder, nonsyndromic congenital, 3	Enrichment	PLCD1	1.45
452	Multiple self-healing squamous epithelioma	Enrichment	TGFBR1	1.45
453	Melanosis, neurocutaneous	Enrichment	NRAS	1.45
454	Noonan syndrome 9	Enrichment	SOS2	1.45
455	Noonan syndrome 6	Enrichment	NRAS	1.45
456	Neurodevelopmental disorder with involuntary movements	Enrichment	GNAO1	1.45
457	Frontometaphyseal dysplasia 2	Enrichment	MAP3K7	1.45
458	Ventricular tachycardia, familial	Enrichment	GNAI2	1.45
459	Hiatt-neu-cooper neurodevelopmental syndrome	Enrichment	RALA	1.45
460	Noonan syndrome 11	Enrichment	MRAS	1.45
461	Spondylometaphyseal dysplasia with corneal dystrophy	Enrichment	PLCB3	1.45
462	Deafness, autosomal recessive 108	Enrichment	ROR1	1.45
463	Myasthenic syndrome, congenital, 9, associated with acetylcholine receptor deficiency	Enrichment	MUSK	1.45
464	Lymphoproliferative syndrome 3	Enrichment	CD70	1.45
465	Immunodeficiency with hyper-igm, type 1	Enrichment	CD40LG	1.45
466	Immunodeficiency 48	Enrichment	ZAP70	1.45
467	Bone marrow failure syndrome 5	Enrichment	TP53	1.45
468	Papilloma of choroid plexus	Enrichment	TP53	1.45
469	Auriculocondylar syndrome 2a	Enrichment	PLCB4	1.45
470	Basal cell carcinoma 7	Enrichment	TP53	1.45
471	Spondylometaepiphyseal dysplasia, short limb-hand type	Enrichment	DDR2	1.45
472	Anaplastic thyroid carcinoma	Enrichment	TP53	1.45
473	Neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language	Enrichment	MEF2C	1.45
474	Neurodevelopmental disorder with hypotonia, impaired speech, and behavioral abnormalities	Enrichment	GNAI1	1.45
475	Asthma-related traits 5	Enrichment	IRAK3	1.45
476	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	1.45
477	Developmental and epileptic encephalopathy 17	Enrichment	GNAO1	1.45
478	Prostate cancer/brain cancer susceptibility	Enrichment	EPHB2	1.45
479	Coronary artery disease, autosomal dominant, 1	Enrichment	MEF2A	1.45
480	Charcot-marie-tooth disease, axonal, type 2f	Enrichment	HSPB1	1.45
481	Immunodeficiency 67	Enrichment	IRAK4	1.45
482	Night blindness, congenital stationary, autosomal dominant 3	Enrichment	GNAT1	1.45
483	Dystonia 25	Enrichment	GNAL	1.45
484	Night blindness, congenital stationary, type 1g	Enrichment	GNAT1	1.45
485	Polydactyly-macrocephaly syndrome	Enrichment	MAX	1.45
486	Nasopharyngeal carcinoma 3	Enrichment	MST1R	1.45
487	Acute myeloid leukemia with minimal differentiation	Enrichment	FLT3	1.45
488	Neurocardiofaciodigital syndrome	Enrichment	MAPKAPK5	1.45
489	Macular dystrophy, patterned, 3	Enrichment	MAPKAPK3	1.45
490	Ductal carcinoma in situ	Enrichment	TP53	1.45
491	Congenital heart defects and ectodermal dysplasia	Enrichment	PRKD1	1.45
492	Autoimmune disease, multisystem, infantile-onset, 2	Enrichment	ZAP70	1.45
493	Congenital heart defects, multiple types, 7	Enrichment	FLT4	1.45
494	Immunodeficiency 22	Enrichment	LCK	1.45
495	Bleeding disorder, platelet-type, 22	Enrichment	EPHB2	1.45
496	Thrombocytopenia 6	Enrichment	SRC	1.45
497	Autoinflammation with episodic fever and lymphadenopathy	Enrichment	RIPK1	1.45
498	Chronic mast cell leukemia	Enrichment	KIT	1.45
499	Warburg-cinotti syndrome	Enrichment	DDR2	1.45
500	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	1.45
501	Auriculocondylar syndrome 2b	Enrichment	PLCB4	1.45
502	Tufted angioma of skin	Enrichment	KDR	1.45
503	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	1.45
504	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	1.45
505	5q14.3 microdeletion syndrome	Enrichment	MEF2C	1.45
506	Isolated bone marrow mastocytosis	Enrichment	KIT	1.45
507	Congenital pulmonary airway malformation	Enrichment	KRAS	1.45
508	Smoldering systemic mastocytosis	Enrichment	KIT	1.45
509	Cerebral cavernous malformations 5	Enrichment	MAP3K3	1.45
510	Choroid plexus cancer	Enrichment	TP53	1.45
511	Alk-positive anaplastic large cell lymphoma	Enrichment	ALK	1.45
512	Cd40 ligand deficiency	Enrichment	CD40LG	1.45
513	Complete atrioventricular septal defect without ventricular hypoplasia	Enrichment	MEF2C	1.45
514	Acute myeloid leukemia with mutated cebpa	Enrichment	CEBPA	1.45
515	Mastocytosis	Enrichment	KIT	1.45
516	Pleomorphic xanthoastrocytoma	Enrichment	TP53	1.45
517	Cutaneous mastocytoma	Enrichment	KIT	1.45
518	Typical urticaria pigmentosa	Enrichment	KIT	1.45
519	Gnao1-related disorder	Enrichment	GNAO1	1.45
520	Phakomatosis pigmentokeratotica	Enrichment	HRAS	1.45
521	Mef2c-related disorder	Enrichment	MEF2C	1.45
522	Nodular urticaria pigmentosa	Enrichment	KIT	1.45
523	Malignant epithelial tumor of salivary glands	Enrichment	PRKD1	1.45
524	Alk-positive large b-cell lymphoma	Enrichment	ALK	1.45
525	Pseudoxanthomatous diffuse cutaneous mastocytosis	Enrichment	KIT	1.45
526	Verrucous hemangioma	Enrichment	MAP3K3	1.45
527	Telangiectasia macularis eruptiva perstans	Enrichment	KIT	1.45
528	Acute mast cell leukemia	Enrichment	KIT	1.45
529	Plaque-form urticaria pigmentosa	Enrichment	KIT	1.45
530	Ephb4-related lymphatic-related hydrops fetalis	Enrichment	EPHB4	1.45
531	Neurocutaneous melanocytosis	Enrichment	NRAS	1.45
532	Bullous diffuse cutaneous mastocytosis	Enrichment	KIT	1.45
533	Zap70-related severe combined immunodeficiency	Enrichment	ZAP70	1.45
534	Polyvalvular heart disease syndrome	Enrichment	TAB2	1.45
535	Vein of galen aneurysmal malformation	Enrichment	EPHB4	1.45
536	Testis seminoma	Enrichment	KIT	1.45
537	Proteus syndrome	Enrichment	AKT1	1.42
538	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	1.42
539	Prostate cancer, hereditary, x-linked 3	Enrichment	AR	1.42
540	Vacterl association with hydrocephalus	Enrichment	PTEN	1.42
541	Androgen insensitivity, partial	Enrichment	AR	1.42
542	Incontinentia pigmenti	Enrichment	IKBKG	1.42
543	Lymphoproliferative syndrome, x-linked, 2	Enrichment	XIAP	1.42
544	Deafness, autosomal recessive 26	Enrichment	GAB1	1.42
545	Autoinflammatory disease, systemic, x-linked	Enrichment	IKBKG	1.42
546	Noonan syndrome 5	Enrichment	RAF1	1.42
547	Febrile seizures, familial, 8	Enrichment	GABRG2	1.42
548	Spinocerebellar ataxia 12	Enrichment	PPP2R2B	1.42
549	Coloboma, ocular, with or without hearing impairment, cleft lip/palate, and/or impaired intellectual development	Enrichment	YAP1	1.42
550	Epilepsy, idiopathic generalized 13	Enrichment	GABRA1	1.42
551	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	1.42
552	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3	Enrichment	CCND2	1.42
553	Fetal encasement syndrome	Enrichment	CHUK	1.42
554	Accelerated tumor formation	Enrichment	MDM2	1.42
555	Immunodeficiency 15b	Enrichment	IKBKB	1.42
556	Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development	Enrichment	PTPA	1.42
557	Immunodeficiency 15a	Enrichment	IKBKB	1.42
558	Developmental and epileptic encephalopathy 74	Enrichment	GABRG2	1.42
559	Developmental and epileptic encephalopathy 79	Enrichment	GABRA5	1.42
560	Lessel-kubisch syndrome	Enrichment	MDM2	1.42
561	Houge-janssens syndrome 4	Enrichment	PPP2R5C	1.42
562	Ectodermal dysplasia and immunodeficiency 1	Enrichment	IKBKG	1.42
563	Pseudohypoaldosteronism, type iic	Enrichment	WNK1	1.42
564	Deafness, dystonia, and cerebral hypomyelination	Enrichment	BCAP31	1.42
565	Autism 19	Enrichment	EIF4E	1.42
566	Epilepsy, x-linked 2, with or without impaired intellectual development and dysmorphic features	Enrichment	GABRA3	1.42
567	Epilepsy, idiopathic generalized 10	Enrichment	GABRD	1.42
568	Papillary tumor of the pineal region	Enrichment	PTEN	1.42
569	Uveal coloboma-cleft lip and palate-intellectual disability	Enrichment	YAP1	1.42
570	Houge-janssens syndrome 2	Enrichment	PPP2R1A	1.42
571	Developmental and epileptic encephalopathy 19	Enrichment	GABRA1	1.42
572	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Enrichment	AKT3	1.42
573	Neuroendocrine tumor	Enrichment	CDKN1B	1.42
574	Leopard syndrome 2	Enrichment	RAF1	1.42
575	Immunodeficiency 26 with or without neurologic abnormalities	Enrichment	PRKDC	1.42
576	Cowden syndrome 6	Enrichment	AKT1	1.42
577	Epilepsy, childhood absence 5	Enrichment	GABRB3	1.42
578	Immunodeficiency 97 with autoinflammation	Enrichment	PIK3CG	1.42
579	Glioma susceptibility 2	Enrichment	PTEN	1.42
580	Developmental and epileptic encephalopathy 56	Enrichment	YWHAG	1.42
581	Developmental and epileptic encephalopathy 92	Enrichment	GABRB2	1.42
582	Lopes-maciel-rodan syndrome	Enrichment	HTT	1.42
583	Developmental and epileptic encephalopathy 43	Enrichment	GABRB3	1.42
584	Developmental and epileptic encephalopathy 45	Enrichment	GABRB1	1.42
585	Bartsocas-papas syndrome 2	Enrichment	CHUK	1.42
586	Trigonitis	Enrichment	RAF1	1.42
587	Capillary hemangioma	Enrichment	AKT3	1.42
588	Oocyte/zygote/embryo maturation arrest 21	Enrichment	CHEK1	1.42
589	Amyotrophic lateral sclerosis type 13	Enrichment	ATXN2	1.42
590	Complete androgen insensitivity syndrome	Enrichment	AR	1.42
591	Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to ikbka deficiency	Enrichment	CHUK	1.42
592	Juvenile huntington disease	Enrichment	HTT	1.42
593	Ppp2r1a-related neurodevelopmental disorder	Enrichment	PPP2R1A	1.42
594	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	Enrichment	PTEN	1.42
595	Distal 17p13.3 microdeletion syndrome	Enrichment	YWHAE	1.42
596	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	1.42
597	Inflammatory bowel disease 1	Enrichment	IL6, PRKCQ	1.42
598	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	CSF3R, FLT3	1.42
599	Primary hyperaldosteronism	Enrichment	GNAS, TP53	1.42
600	Immune deficiency disease	Enrichment	CD27, SYK	1.39
601	Cowden syndrome	Enrichment	AKT1, PTEN	1.36
602	Renal hypodysplasia/aplasia 3	Enrichment	BMP4, FGFR3	1.32
603	Myocardial infarction	Enrichment	ITGB3, LTA, TNFSF4	1.31
604	Leukemia, chronic lymphocytic	Enrichment	CCND1, TP53	1.28
605	Dravet syndrome	Enrichment	GABRA1, GABRG2	1.28
606	Hirschsprung disease 1	Enrichment	ERBB2, ERBB3, NRG3	1.26
607	Severe covid-19	Enrichment	IL10RB, ITGAV, JAK3	1.26
608	Leukemia, acute lymphoblastic	Enrichment	FLT3, GNB1	1.25
609	Myelodysplastic syndrome	Enrichment	GNB1, TP53	1.25
610	Acute promyelocytic leukemia	Enrichment	STAT3, STAT5B	1.25
611	Alzheimer's disease	Enrichment	CSF1R, TNF	1.25
612	Acromicric dysplasia	Enrichment	LTBP3	1.23
613	Cri-du-chat syndrome	Enrichment	SEMA5A	1.23
614	Leukocyte adhesion deficiency, type i	Enrichment	ITGB2	1.23
615	Blue rubber bleb nevus	Enrichment	TEK	1.23
616	Familial expansile osteolysis	Enrichment	TNFRSF11A	1.23
617	Sorsby fundus dystrophy	Enrichment	TIMP3	1.23
618	Myeloproliferative disorder, chronic, with eosinophilia	Enrichment	PDGFRB	1.23
619	Pseudohypoparathyroidism, type ia	Enrichment	GNAS	1.23
620	Camurati-engelmann disease 1	Enrichment	TGFB1	1.23
621	Insensitivity to pain, congenital, with anhidrosis	Enrichment	NTRK1	1.23
622	Trichomegaly	Enrichment	FGF5	1.23
623	Paget disease of bone 5, juvenile-onset	Enrichment	TNFRSF11A	1.23
624	Hemangiopericytoma, malignant	Enrichment	STAT6	1.23
625	Immunodeficiency, common variable, 2	Enrichment	TNFRSF13B	1.23
626	Visceral neuropathy, familial, 1, autosomal recessive	Enrichment	ERBB3	1.23
627	Cutis marmorata telangiectatica congenita	Enrichment	GNA11	1.23
628	Growth hormone insensitivity syndrome with immune dysregulation 1, autosomal recessive	Enrichment	STAT5B	1.23
629	Kyphomelic dysplasia	Enrichment	CCN2	1.23
630	Neutropenia, severe congenital, x-linked	Enrichment	WAS	1.23
631	Omodysplasia 1	Enrichment	GPC6	1.23
632	Pulmonary venoocclusive disease 1, autosomal dominant	Enrichment	BMPR2	1.23
633	Pulmonary hypoplasia, primary	Enrichment	FGF10	1.23
634	Dermatofibrosarcoma protuberans	Enrichment	PDGFB	1.23
635	Wiskott-aldrich syndrome	Enrichment	WAS	1.23
636	West nile virus	Enrichment	CCR5	1.23
637	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	PIK3R5	1.23
638	Isolated growth hormone deficiency, type iii, with agammaglobulinemia	Enrichment	BTK	1.23
639	Immunodeficiency 41 with lymphoproliferation and autoimmunity	Enrichment	IL2RA	1.23
640	Parkinson disease 8, autosomal dominant	Enrichment	GDF6	1.23
641	Pigmented nodular adrenocortical disease, primary, 1	Enrichment	GNAS	1.23
642	Aortic aneurysm, familial thoracic 2	Enrichment	ACTA2	1.23
643	Inflammatory bowel disease 28, autosomal recessive	Enrichment	IL10RA	1.23
644	Pseudopseudohypoparathyroidism	Enrichment	GNAS	1.23
645	Immunodeficiency with hyper-igm, type 2	Enrichment	TNFRSF13B	1.23
646	Hyperinsulinemic hypoglycemia, familial, 4	Enrichment	INSR	1.23
647	Aural atresia, congenital	Enrichment	FGFR2	1.23
648	Deafness, autosomal dominant 20	Enrichment	ACTG1	1.23
649	Keratosis, seborrheic	Enrichment	FGFR3	1.23
650	Multiple synostoses syndrome 2	Enrichment	GDF5	1.23
651	Smooth muscle dysfunction syndrome	Enrichment	ACTA2	1.23
652	Leukocyte adhesion deficiency, type iii	Enrichment	ITGB2	1.23
653	Neutrophilia, hereditary	Enrichment	CSF3R	1.23
654	Myopathy, mitochondrial progressive, with congenital cataract and developmental delay	Enrichment	GFER	1.23
655	Cutis laxa, autosomal recessive, type ic	Enrichment	LTBP4	1.23
656	Aortic aneurysm, familial thoracic 6	Enrichment	ACTA2	1.23
657	Baraitser-winter syndrome 2	Enrichment	ACTG1	1.23
658	Silver-russell syndrome 3	Enrichment	IGF2	1.23
659	Osteogenesis imperfecta, type xiii	Enrichment	BMP1	1.23
660	Moyamoya disease 5	Enrichment	ACTA2	1.23
661	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	1.23
662	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	1.23
663	Thrombocythemia 3	Enrichment	JAK2	1.23
664	Immunodeficiency 51	Enrichment	IL17RA	1.23
665	Heterotaxy, visceral, 4, autosomal	Enrichment	ACVR2B	1.23
666	Neutropenia, severe congenital, 7, autosomal recessive	Enrichment	CSF3R	1.23
667	Brachydactyly, type a1, c	Enrichment	GDF5	1.23
668	Symphalangism, proximal, 1b	Enrichment	GDF5	1.23
669	Immunodeficiency 31c	Enrichment	STAT1	1.23
670	Pain sensitivity quantitative trait locus 1	Enrichment	NTRK1	1.23
671	Antley-bixler syndrome without genital anomalies or disordered steroidogenesis	Enrichment	FGFR2	1.23
672	Spondyloepimetaphyseal dysplasia, li-shao-li type	Enrichment	CCN2	1.23
673	Waardenburg syndrome, type 2f	Enrichment	KITLG	1.23
674	Lymphatic malformation 11	Enrichment	TIE1	1.23
675	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	1.23
676	Agammaglobulinemia, x-linked	Enrichment	BTK	1.23
677	Epidermolysis bullosa, junctional 5a, intermediate	Enrichment	ITGB4	1.23
678	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.23
679	Kowarski syndrome	Enrichment	GH1	1.23
680	Infantile myofibromatosis	Enrichment	PDGFRB	1.23
681	Pulmonary venoocclusive disease 1	Enrichment	BMPR2	1.23
682	Intravascular large b-cell lymphoma	Enrichment	BCL2	1.23
683	Primary cutaneous amyloidosis	Enrichment	OSMR	1.23
684	Epidermolysis bullosa, junctional 7, with interstitial lung disease and nephrotic syndrome	Enrichment	ITGA3	1.23
685	Immunodeficiency 127	Enrichment	TNF	1.23
686	Childhood hepatocellular carcinoma	Enrichment	MET	1.23
687	Lymphoproliferative syndrome	Enrichment	ITK	1.23
688	Immunodeficiency, common variable, 4	Enrichment	TNFRSF13C	1.23
689	Split hand-foot malformation	Enrichment	FGFR2	1.23
690	Rosette-forming glioneuronal tumor	Enrichment	FGFR1	1.23
691	Autosomal dominant hypocalcemia	Enrichment	GNA11	1.23
692	Leprosy 1	Enrichment	TLR6	1.23
693	Pseudohypoparathyroidism	Enrichment	GNAS	1.23
694	Papillary renal cell carcinoma	Enrichment	MET	1.23
695	Congenital mesoblastic nephroma	Enrichment	NTRK3	1.23
696	Camurati-engelmann disease	Enrichment	TGFB1	1.23
697	Inflammatory bowel disease 28	Enrichment	IL10RA	1.23
698	Severe congenital neutropenia 7	Enrichment	CSF3R	1.23
699	Immunodeficiency 104, severe combined	Enrichment	IL7R	1.23
700	Microphthalmia/coloboma 6	Enrichment	GDF6	1.23
701	Autoinflammation, immune dysregulation, and eosinophilia	Enrichment	JAK1	1.23
702	Multiple sclerosis 3	Enrichment	IL7R	1.23
703	Immunodeficiency 17	Enrichment	CD3G	1.23
704	Immune system disease	Enrichment	CDC42	1.23
705	Fibrosarcoma	Enrichment	NTRK3	1.23
706	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	1.23
707	Proximal symphalangism	Enrichment	GDF5	1.23
708	Polycythemia	Enrichment	JAK2	1.23
709	Craniosynostosis 7	Enrichment	BMP2	1.23
710	Immunodeficiency 52	Enrichment	LAT	1.23
711	Congenital amegakaryocytic thrombocytopenia	Enrichment	THPO	1.23
712	Hereditary mixed polyposis syndrome	Enrichment	BMPR1A	1.23
713	Lymphatic malformation 10	Enrichment	ANGPT2	1.23
714	Interfrontal craniofaciosynostosis	Enrichment	FGFR1	1.23
715	Intermittent hydrarthrosis	Enrichment	TNFRSF1A	1.23
716	Short stature due to growth hormone qualitative anomaly	Enrichment	GH1	1.23
717	Localized junctional epidermolysis bullosa, non-herlitz type	Enrichment	ITGB4	1.23
718	Autosomal dominant nonsyndromic deafness	Enrichment	FGFR2	1.23
719	Chronic eosinophilic leukemia	Enrichment	PDGFRA	1.23
720	Growth delay due to insulin-like growth factor type 1 deficiency	Enrichment	IGF1	1.23
721	Arthritis	Enrichment	SYK	1.23
722	Acth-independent macronodular adrenal hyperplasia	Enrichment	GNAS	1.23
723	Hypereosinophilic syndrome	Enrichment	JAK2	1.23
724	Pulmonary venoocclusive disease	Enrichment	BMPR2	1.23
725	B-lymphoblastic leukemia/lymphoma with recurrent genetic abnormality	Enrichment	PDGFRA	1.23
726	Transient predisposition to invasive pyogenic bacterial infection	Enrichment	MYD88	1.23
727	Common variable immunodeficiency 12	Enrichment	NFKB1	1.23
728	Silver-russell syndrome due to an imprinting defect of 11p15	Enrichment	IGF2	1.23
729	Oculootodental syndrome	Enrichment	FADD	1.23
730	Intestinal obstruction	Enrichment	ACTG2	1.23
731	Idiopathic/heritable pulmonary arterial hypertension	Enrichment	BMPR2	1.23
732	Laron syndrome with immunodeficiency	Enrichment	STAT5B	1.23
733	Cerebral visual impairment	Enrichment	GNB1	1.23
734	Phakomatosis cesioflammea	Enrichment	GNA11	1.23
735	Silver-russell syndrome due to 11p15 microduplication	Enrichment	IGF2	1.23
736	Tetralogy of fallot	Enrichment	EPHB4, FLT4, KDR	1.20
737	Hydrops fetalis, nonimmune	Enrichment	EPHB4, FLT4, HRAS	1.20
738	Epilepsy, myoclonic juvenile	Enrichment	GABRA1, GABRD	1.20
739	Epilepsy, idiopathic generalized	Enrichment	GABRA1, GABRD	1.20
740	Meningioma, familial	Enrichment	PDGFB, PTEN	1.20
741	Multiple sclerosis	Enrichment	ITGB4, TNFRSF1A	1.19
742	Cleft lip/palate	Enrichment	BMP4, PDGFRA	1.19
743	Fibromatosis, gingival, 1	Enrichment	SOS1	1.16
744	Adrenocortical carcinoma, hereditary	Enrichment	TP53	1.16
745	Costello syndrome	Enrichment	HRAS	1.16
746	Pituitary adenoma 4, acth-secreting	Enrichment	GNAI2	1.16
747	Immunodeficiency 33	Enrichment	IRAK4	1.16
748	Pulmonic stenosis	Enrichment	SOS1	1.16
749	Loeys-dietz syndrome 2	Enrichment	TGFBR1	1.16
750	Histiocytoma, angiomatoid fibrous	Enrichment	CREB1	1.16
751	Piebald trait	Enrichment	KIT	1.16
752	Neuronopathy, distal hereditary motor, autosomal dominant 3	Enrichment	HSPB1	1.16
753	Spermatogenic failure 17	Enrichment	PLCZ1	1.16
754	Lymphoma, hodgkin, classic	Enrichment	TP53	1.16
755	Osteopetrosis, autosomal recessive 2	Enrichment	TNFSF11	1.16
756	Noonan syndrome 12	Enrichment	RRAS2	1.16
757	Congenital fibrosarcoma	Enrichment	TP53	1.16
758	Li-fraumeni syndrome 1	Enrichment	TP53	1.16
759	Sarcoma	Enrichment	TP53	1.16
760	Congenital dyserythropoietic anemia	Enrichment	IRAK4	1.16
761	Ocular melanoma	Enrichment	PLCB4	1.16
762	Congenital heart defects, multiple types, 2	Enrichment	TAB2	1.16
763	Hodgkin's lymphoma	Enrichment	TP53	1.16
764	Hypopituitarism	Enrichment	GNAI2	1.16
765	Retinitis pigmentosa 38	Enrichment	MERTK	1.16
766	Immunodeficiency 57 with autoinflammation	Enrichment	RIPK1	1.16
767	Acute myeloid leukemia without maturation	Enrichment	FLT3	1.16
768	Cardiac anomalies-short stature-joint hypermobility-facial dysmorphism syndrome	Enrichment	TAB2	1.16
769	Mixed phenotype acute leukemia with t(9;22)(q34.1;q11.2)	Enrichment	FLT3	1.16
770	B-lymphoblastic leukemia/lymphoma with t	Enrichment	KIT	1.16
771	Pleomorphic rhabdomyosarcoma	Enrichment	TP53	1.16
772	Wooly hair nevus	Enrichment	HRAS	1.16
773	Congenital myopathy 4a, autosomal dominant	Enrichment	ACTA1, ITGA7	1.14
774	Hydrocephalus	Enrichment	FGFR2, PDGFRB	1.14
775	Spinocerebellar ataxia 1	Enrichment	ATXN1	1.13
776	Spinocerebellar ataxia 7	Enrichment	ATXN7	1.13
777	Granulomatous disease, chronic, autosomal recessive, 1	Enrichment	NCF1	1.13
778	Glycogen storage disease 0, liver	Enrichment	GYS2	1.13
779	Glycogen storage disease vii	Enrichment	PFKM	1.13
780	Spinal and bulbar muscular atrophy, x-linked 1	Enrichment	AR	1.13
781	Vitamin d hydroxylation-deficient rickets, type 1b	Enrichment	PDE3B	1.13
782	Multiple endocrine neoplasia, type iv	Enrichment	CDKN1B	1.13
783	Houge-janssens syndrome 1	Enrichment	PPP2R5D	1.13
784	Spinocerebellar ataxia 2	Enrichment	ATXN2	1.13
785	46,xy sex reversal 1	Enrichment	AR	1.13
786	Androgen insensitivity syndrome	Enrichment	AR	1.13
787	Cebalid syndrome	Enrichment	MTOR	1.13
788	Hypospadias 1, x-linked	Enrichment	AR	1.13
789	Glycogen storage disease 0, muscle	Enrichment	GYS1	1.13
790	Senior-loken syndrome 7	Enrichment	AKT3	1.13
791	Ectodermal dysplasia and immune deficiency	Enrichment	IKBKG	1.13
792	Developmental and epileptic encephalopathy 78	Enrichment	GABRA2	1.13
793	Bardet-biedl syndrome 16	Enrichment	AKT3	1.13
794	Smith-kingsmore syndrome	Enrichment	MTOR	1.13
795	Glucosephosphate dehydrogenase deficiency	Enrichment	IKBKG	1.13
796	Glycogen storage disorder due to hepatic glycogen synthase deficiency	Enrichment	GYS2	1.13
797	Houge-janssens syndrome 3	Enrichment	PPP2CA	1.13
798	Cadds	Enrichment	BCAP31	1.13
799	Vacterl with hydrocephalus	Enrichment	PTEN	1.13
800	Posterior hypospadias	Enrichment	AR	1.13
801	Glycogen storage disease due to muscle and heart glycogen synthase deficiency	Enrichment	GYS1	1.13
802	Aortic valve disease 1	Enrichment	SOS1, TAB2	1.12
803	Cakut	Enrichment	ACTG1, GDF6, LIFR	1.09
804	Hereditary breast carcinoma	Enrichment	AKT1, KRAS, PTEN, TP53	1.07
805	Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-negative, nk cell-negative, due to adenosine deaminase deficiency	Enrichment	JAK3	1.06
806	Achondroplasia	Enrichment	FGFR3	1.06
807	Mccune-albright syndrome	Enrichment	GNAS	1.06
808	Hypogonadotropic hypogonadism 2 with or without anosmia	Enrichment	FGFR1	1.06
809	Larsen syndrome	Enrichment	FGFR3	1.06
810	Klippel-feil syndrome 1, autosomal dominant	Enrichment	GDF6	1.06
811	Thyroid carcinoma, familial medullary	Enrichment	NTRK1	1.06
812	Juvenile polyposis syndrome	Enrichment	BMPR1A	1.06
813	Exfoliation syndrome	Enrichment	LTBP2	1.06
814	Tumoral calcinosis, hyperphosphatemic, familial, 1	Enrichment	FGF23	1.06
815	Thrombocythemia 1	Enrichment	THPO	1.06
816	Hypophosphatemic rickets, autosomal dominant	Enrichment	FGF23	1.06
817	Dysosteosclerosis	Enrichment	TNFRSF11A	1.06
818	Takayasu arteritis	Enrichment	IL12B	1.06
819	Polycythemia vera	Enrichment	JAK2	1.06
820	Leukoencephalopathy, hereditary diffuse, with spheroids 1	Enrichment	CSF1R	1.06
821	Severe combined immunodeficiency, x-linked	Enrichment	IL2RG	1.06
822	Agammaglobulinemia 1, autosomal recessive	Enrichment	BTK	1.06
823	Stuve-wiedemann syndrome 1	Enrichment	LIFR	1.06
824	Muscular dystrophy, duchenne type	Enrichment	LTBP4	1.06
825	Combined immunodeficiency, x-linked	Enrichment	IL2RG	1.06
826	Transposition of the great arteries, dextro-looped	Enrichment	BMP2	1.06
827	Hepatitis c virus	Enrichment	CCR5	1.06
828	Muscular dystrophy, congenital, due to integrin alpha-7 deficiency	Enrichment	ITGA7	1.06
829	Chromosome 8p11 myeloproliferative syndrome	Enrichment	FGFR1	1.06
830	Dyskeratosis congenita, autosomal dominant 6	Enrichment	THPO	1.06
831	Neonatal nephrocutaneous inflammatory syndrome	Enrichment	EGFR	1.06
832	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	1.06
833	Epidermolysis bullosa, junctional 6, with pyloric atresia	Enrichment	ITGA6	1.06
834	Weill-marchesani syndrome 1	Enrichment	LTBP2	1.06
835	Agammaglobulinemia 1	Enrichment	BTK	1.06
836	Primary polycythemia	Enrichment	EPOR	1.06
837	Autosomal recessive cutis laxa type i	Enrichment	LTBP1	1.06
838	Hyper ige syndrome	Enrichment	STAT3	1.06
839	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	BCL2	1.06
840	Isolated growth hormone deficiency, type ib	Enrichment	GH1	1.06
841	Inflammatory bowel disease 25	Enrichment	IL10RB	1.06
842	Immunodeficiency 14	Enrichment	PIK3R1	1.06
843	T-cell acute lymphoblastic leukemia	Enrichment	BAX	1.06
844	Migraine without aura	Enrichment	TNF	1.06
845	Immunodeficiency 44	Enrichment	STAT2	1.06
846	Cushing syndrome due to bilateral macronodular adrenocortical disease	Enrichment	GNAS	1.06
847	Growth delay due to insulin-like growth factor i resistance	Enrichment	IGF1R	1.06
848	High bone mass osteogenesis imperfecta	Enrichment	BMP1	1.06
849	Bleeding disorder, platelet-type, 24	Enrichment	ITGB3	1.06
850	Adult-onset myasthenia gravis	Enrichment	TNFRSF11A	1.06
851	Neonatal inflammatory skin and bowel disease	Enrichment	EGFR	1.06
852	Geleophysic dysplasia	Enrichment	LTBP3	1.06
853	Alopecia - intellectual disability syndrome	Enrichment	ITGB6	1.06
854	Renal cell carcinoma	Enrichment	MET	1.06
855	Stüve-wiedemann syndrome	Enrichment	LIFR	1.06
856	Testicular cancer	Enrichment	FGFR3	1.06
857	Pulmonary arterial hypertension associated with congenital heart disease	Enrichment	BMPR2	1.06
858	Isolated klippel-feil syndrome	Enrichment	GDF6	1.06
859	Beckwith-wiedemann syndrome due to imprinting defect of 11p15	Enrichment	IGF2	1.06
860	Vogt-koyanagi-harada disease	Enrichment	FAS	1.06
861	Pelvic organ prolapse	Enrichment	TAB2	0.99
862	Nuchal bleb, familial	Enrichment	SOS1	0.99
863	Langerhans cell histiocytosis	Enrichment	NRAS	0.99
864	Osteogenic sarcoma	Enrichment	TP53	0.99
865	Nasopharyngeal carcinoma	Enrichment	TP53	0.99
866	Nephrotic syndrome, type 3	Enrichment	PLCE1	0.99
867	Bronchopulmonary dysplasia	Enrichment	MUSK	0.99
868	Bacteremia 2	Enrichment	MAPKAPK3	0.99
869	Loeys-dietz syndrome 1	Enrichment	TGFBR1	0.99
870	Lymphatic malformation 7	Enrichment	EPHB4	0.99
871	Atypical teratoid rhabdoid tumor	Enrichment	TP53	0.99
872	Anaplastic astrocytoma	Enrichment	TP53	0.99
873	Frontometaphyseal dysplasia	Enrichment	MAP3K7	0.99
874	Capillary malformation-arteriovenous malformation 2	Enrichment	EPHB4	0.99
875	Myxoid liposarcoma	Enrichment	DDIT3	0.99
876	Squamous cell carcinoma	Enrichment	TP53	0.99
877	Adenocarcinoma	Enrichment	TP53	0.99
878	Immunodeficiency, common variable, 11	Enrichment	IL21	0.99
879	Bone osteosarcoma	Enrichment	TP53	0.99
880	Melanoma of soft tissue	Enrichment	CREB1	0.99
881	Mixed phenotype acute leukemia with t	Enrichment	FLT3	0.99
882	Renal cell carcinoma, nonpapillary	Enrichment	MET, MTOR	0.96
883	Granulomatous disease, chronic, autosomal recessive, 2	Enrichment	NCF1	0.96
884	Polycystic kidney disease, infantile severe, with tuberous sclerosis	Enrichment	TSC2	0.96
885	Vitamin d hydroxylation-deficient rickets, type 1a	Enrichment	PDE3B	0.96
886	Spinocerebellar ataxia 10	Enrichment	ATXN10	0.96
887	Tuberous sclerosis 2	Enrichment	TSC2	0.96
888	Miller-dieker lissencephaly syndrome	Enrichment	YWHAE	0.96
889	Chromosome 17p13.3, centromeric, duplication syndrome	Enrichment	YWHAE	0.96
890	Dedifferentiated liposarcoma	Enrichment	MDM2	0.96
891	Xanthinuria, type ii	Enrichment	TSC2	0.96
892	Well-differentiated liposarcoma	Enrichment	MDM2	0.96
893	Thyrotoxic periodic paralysis	Enrichment	GABRA3	0.96
894	Kaposi sarcoma	Enrichment	IL6	0.94
895	Amelogenesis imperfecta, type iiia	Enrichment	ITGB6	0.94
896	Isolated growth hormone deficiency, type ii	Enrichment	GH1	0.94
897	Nemaline myopathy 2	Enrichment	ACTA1	0.94
898	Anemia, autoimmune hemolytic	Enrichment	TLR8	0.94
899	Megacystis-microcolon-intestinal hypoperistalsis syndrome 1	Enrichment	ACTG2	0.94
900	Spastic paraplegia 17, autosomal dominant	Enrichment	GNG3	0.94
901	Hemophilia a	Enrichment	ACVRL1	0.94
902	Pseudohypoparathyroidism, type ib	Enrichment	GNAS	0.94
903	Budd-chiari syndrome	Enrichment	JAK2	0.94
904	Microtia-anotia	Enrichment	BMP5	0.94
905	Paget disease of bone 2, early-onset	Enrichment	TNFRSF11A	0.94
906	Lipodystrophy, congenital generalized, type 2	Enrichment	GNG3	0.94
907	Epidermolysis bullosa simplex 5c, with pyloric atresia	Enrichment	ITGB4	0.94
908	Immunodeficiency, common variable, 1	Enrichment	TNFRSF13B	0.94
909	Retinitis pigmentosa 26	Enrichment	ITGA4	0.94
910	Factor viii deficiency	Enrichment	ACVRL1	0.94
911	Barrett esophagus	Enrichment	ERBB2	0.94
912	Aminoacylase 1 deficiency	Enrichment	ACTB	0.94
913	Congenital generalized lipodystrophy	Enrichment	FOS	0.94
914	Weill-marchesani syndrome	Enrichment	LTBP2	0.94
915	Hereditary ataxia	Enrichment	PRKCG	0.94
916	Hepatitis b	Enrichment	IL10RB	0.94
917	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CDC42	0.94
918	Adenosine deaminase deficiency	Enrichment	JAK3	0.94
919	Knobloch syndrome	Enrichment	PAK2	0.94
920	Paget's disease of bone 2	Enrichment	TNFRSF11A	0.94
921	Cerebral malaria	Enrichment	TNF	0.94
922	Silver-russell syndrome due to a point mutation	Enrichment	IGF2	0.94
923	Inherited epidermodysplasia verruciformis	Enrichment	IL7	0.94
924	Non-syndromic bicoronal craniosynostosis	Enrichment	FGFR3	0.94
925	Intermediate nemaline myopathy	Enrichment	ACTA1	0.94
926	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	0.94
927	Hereditary angioedema with normal c1inh not related to f12 or plg variant	Enrichment	ANGPT1	0.94
928	Familial sick sinus syndrome	Enrichment	GNB2	0.94
929	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB	0.94
930	Alzheimer disease, familial, 1	Enrichment	CSF1R, NOS3	0.87
931	Hypertension, essential	Enrichment	GNB3, NOS3	0.87
932	Cardiofaciocutaneous syndrome 1	Enrichment	KRAS	0.87
933	Diffuse gastric and lobular breast cancer syndrome	Enrichment	KRAS	0.87
934	Small cell cancer of the lung	Enrichment	TP53	0.87
935	Thyroid cancer, nonmedullary, 1	Enrichment	TP53	0.87
936	Cholangiocarcinoma	Enrichment	ROS1	0.87
937	Developmental and epileptic encephalopathy 12	Enrichment	PLCB1	0.87
938	Cardiofaciocutaneous syndrome	Enrichment	KRAS	0.87
939	Chronic myelomonocytic leukemia	Enrichment	FLT3	0.87
940	Embryonal rhabdomyosarcoma	Enrichment	TP53	0.87
941	Aortic aneurysm	Enrichment	TGFBR1	0.87
942	Tuberculosis	Enrichment	MAPKAPK3	0.87
943	Pilocytic astrocytoma	Enrichment	KRAS	0.87
944	Epidermolytic nevus	Enrichment	HRAS	0.87
945	Autosomal recessive osteopetrosis	Enrichment	TNFSF11	0.87
946	Systemic mastocytosis with associated hematologic neoplasm	Enrichment	KIT	0.87
947	Gingival fibromatosis	Enrichment	SOS1	0.87
948	Male infertility due to gonadal dysgenesis or sperm disorder	Enrichment	SOS2	0.87
949	Visceral heterotaxy	Enrichment	ACVR2B, LEFTY2	0.86
950	Tooth agenesis	Enrichment	FGFR1, TGFA	0.86
951	Multisystem inflammatory syndrome in children	Enrichment	TLR3, TLR6	0.86
952	Capillary malformations, congenital	Enrichment	GNA11	0.85
953	Arrhythmogenic right ventricular dysplasia, familial, 1	Enrichment	TGFB3	0.85
954	Visceral myopathy 1	Enrichment	ACTG2	0.85
955	Epidermolysis bullosa simplex 1c, localized	Enrichment	ITGB4	0.85
956	Microcephaly 1, primary, autosomal recessive	Enrichment	ANGPT2	0.85
957	Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-negative	Enrichment	JAK3	0.85
958	Congenital myopathy 3 with rigid spine	Enrichment	ACTA1	0.85
959	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	0.85
960	Atrioventricular septal defect	Enrichment	BMP5	0.85
961	Knobloch syndrome 1	Enrichment	PAK2	0.85
962	Mosaic variegated aneuploidy syndrome 1	Enrichment	PAK6	0.85
963	Congenital heart defects, multiple types, 4	Enrichment	BMP7	0.85
964	Glanzmann thrombasthenia 2	Enrichment	ITGB3	0.85
965	Follicular lymphoma	Enrichment	BCL2	0.85
966	Myeloproliferative neoplasm	Enrichment	JAK2	0.85
967	Epidermolysis bullosa	Enrichment	ITGA6	0.85
968	Juvenile glaucoma	Enrichment	LTBP2	0.85
969	Arrhythmogenic right ventricular dysplasia 1	Enrichment	TGFB3	0.85
970	Histiocytoid hemangioma	Enrichment	FOS	0.85
971	Aplasia cutis congenita	Enrichment	ITGB4	0.85
972	Vascular dementia	Enrichment	TNF	0.85
973	Herpes simplex virus encephalitis	Enrichment	TLR3	0.85
974	Coloboma of choroid and retina	Enrichment	ACTG1	0.85
975	Severe congenital nemaline myopathy	Enrichment	ACTA1	0.85
976	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	BMPR1A	0.85
977	Familial cerebral saccular aneurysm	Enrichment	ANGPTL6	0.85
978	Huntington disease	Enrichment	HTT	0.84
979	Neuropathy, hereditary sensory and autonomic, type iia	Enrichment	WNK1	0.84
980	Granulomatous disease, chronic, x-linked	Enrichment	NCF1	0.84
981	Mantle cell lymphoma	Enrichment	CCND1	0.84
982	Hereditary sensory and autonomic neuropathy type 2	Enrichment	WNK1	0.84
983	Autosomal dominant nocturnal frontal lobe epilepsy	Enrichment	GABRG2	0.84
984	Malignant epithelioid hemangioendothelioma	Enrichment	YAP1	0.84
985	Noonan syndrome with multiple lentigines	Enrichment	RAF1	0.84
986	Primary hyperparathyroidism	Enrichment	CDKN1B	0.84
987	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	ACTA2, TGFB2, TGFB3	0.84
988	Malaria	Enrichment	TIRAP, TNF	0.82
989	Parkinson's disease	Enrichment	ATXN2, ATXN3	0.79
990	Cataract 6, multiple types	Enrichment	EPHA2	0.78
991	Ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant	Enrichment	TRAF6	0.78
992	Neuronopathy, distal hereditary motor, autosomal dominant 2	Enrichment	HSPB1	0.78
993	Robinow syndrome, autosomal recessive 1	Enrichment	ROR2	0.78
994	Night blindness, congenital stationary, type 1c	Enrichment	GNAT1	0.78
995	Lymphoma	Enrichment	TP53	0.78
996	Aniridia	Enrichment	EPHA2	0.78
997	Inherited acute myeloid leukemia	Enrichment	CEBPA	0.78
998	Glaucoma, primary open angle	Enrichment	LTBP2	0.78
999	Telangiectasia, hereditary hemorrhagic, type 1	Enrichment	ACVRL1	0.78
1000	Epidermolysis bullosa, junctional 1a, intermediate	Enrichment	ITGB4	0.78
1001	Split-hand/foot malformation 1	Enrichment	FGFR2	0.78
1002	Wilms tumor, aniridia, genitourinary anomalies, and impaired intellectual development syndrome	Enrichment	BDNF	0.78
1003	Moyamoya disease 1	Enrichment	ACTA2	0.78
1004	Type 1 diabetes mellitus	Enrichment	IL6	0.78
1005	Dental anomalies and short stature	Enrichment	LTBP3	0.78
1006	Anterior segment dysgenesis 5	Enrichment	BMP4	0.78
1007	Mitochondrial dna depletion syndrome 1	Enrichment	TYMP	0.78
1008	Junctional epidermolysis bullosa non-herlitz type	Enrichment	ITGB4	0.78
1009	Intestinal pseudo-obstruction	Enrichment	ACTG2	0.78
1010	Typical nemaline myopathy	Enrichment	ACTA1	0.78
1011	Hepatoblastoma	Enrichment	FGFR3, TP53	0.77
1012	Alzheimer disease 2	Enrichment	NOS3	0.76
1013	Von hippel-lindau syndrome	Enrichment	CCND1	0.76
1014	Anemia, congenital, nonspherocytic hemolytic, 1	Enrichment	IKBKG	0.76
1015	Macrocephaly/autism syndrome	Enrichment	PTEN	0.76
1016	Hemangioma	Enrichment	PTEN	0.76
1017	Endometrial stromal sarcoma	Enrichment	YWHAE	0.76
1018	Hepatocellular carcinoma	Enrichment	MET, TP53	0.74
1019	Primary ovarian insufficiency	Enrichment	BMP6, KDR, NOS3, NTRK1	0.73
1020	Endometrial cancer	Enrichment	FGFR2, PTEN	0.73
1021	Silver-russell syndrome 1	Enrichment	IGF2	0.72
1022	Myelofibrosis	Enrichment	JAK2	0.72
1023	Waardenburg syndrome, type 2e	Enrichment	KITLG	0.72
1024	Brachydactyly	Enrichment	GNAS	0.72
1025	Epidermolysis bullosa simplex	Enrichment	ITGB4	0.72
1026	Childhood-onset nemaline myopathy	Enrichment	ACTA1	0.72
1027	Hypophosphatemic rickets	Enrichment	FGF23	0.72
1028	Inflammatory myofibroblastic tumor	Enrichment	ALK	0.71
1029	Autosomal recessive robinow syndrome	Enrichment	ROR2	0.71
1030	Adrenocortical carcinoma	Enrichment	TP53	0.71
1031	Classic ehlers-danlos syndrome	Enrichment	TGFBR1	0.71
1032	Congenital stationary night blindness	Enrichment	GNAT1, GNB3	0.71
1033	West syndrome	Enrichment	GNAO1, NTRK2, PLCB1	0.69
1034	Angelman syndrome	Enrichment	GABRG3	0.68
1035	Alcohol dependence	Enrichment	GABRA2	0.68
1036	Machado-joseph disease	Enrichment	ATXN3	0.68
1037	Epilepsy, childhood absence 1	Enrichment	GABRB3	0.68
1038	Keratoconus	Enrichment	TSC1	0.68
1039	Kidney clear cell sarcoma	Enrichment	YWHAE	0.68
1040	Arthrogryposis, distal, type 1a	Enrichment	MET	0.67
1041	Spastic paraplegia 4, autosomal dominant	Enrichment	GNAS	0.67
1042	Renal hypodysplasia/aplasia 1	Enrichment	ITGA8	0.67
1043	Isolated growth hormone deficiency, type ia	Enrichment	GH1	0.67
1044	Mitochondrial dna depletion syndrome 4b	Enrichment	TYMP	0.67
1045	Severe congenital neutropenia	Enrichment	CSF3R	0.67
1046	Mosaic variegated aneuploidy syndrome	Enrichment	PAK6	0.67
1047	Hypothyroidism	Enrichment	GNB1	0.67
1048	Permanent neonatal diabetes mellitus	Enrichment	STAT3	0.67
1049	Pancreatic cancer	Enrichment	KRAS, TP53	0.66
1050	Esophageal cancer	Enrichment	TP53	0.65
1051	Parkinson disease, late-onset	Enrichment	ATXN2, ATXN3	0.64
1052	Autoinflammatory disease	Enrichment	TNFRSF1A, XIAP	0.64
1053	Polycystic kidney disease 1 with or without polycystic liver disease	Enrichment	TSC2	0.63
1054	Polycystic kidney disease 1	Enrichment	TSC2	0.63
1055	Megacolon	Enrichment	AKT3	0.63
1056	Tooth agenesis, selective, 1	Enrichment	BMPR2	0.62
1057	Orofacial cleft 1	Enrichment	FGF10	0.62
1058	Charge syndrome	Enrichment	TNFRSF1A	0.62
1059	Leukemia, acute lymphoblastic 3	Enrichment	JAK2	0.62
1060	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1	0.62
1061	Hypogonadotropic hypogonadism	Enrichment	FGFR1	0.62
1062	Congenital central hypoventilation syndrome	Enrichment	BDNF	0.62
1063	Ventricular septal defect	Enrichment	TEK	0.62
1064	Mitochondrial neurogastrointestinal encephalomyopathy	Enrichment	TYMP	0.62
1065	Connective tissue disease	Enrichment	ACTA2, FGFR3	0.60
1066	Narcolepsy 1	Enrichment	TNFSF4	0.60
1067	Lymphoma, non-hodgkin, familial	Enrichment	TP53	0.60
1068	Ewing sarcoma	Enrichment	ETV1	0.60
1069	Neuroblastoma	Enrichment	ALK	0.60
1070	Choreatic disease	Enrichment	GNAO1	0.60
1071	Early-onset posterior polar cataract	Enrichment	EPHA2	0.60
1072	Cat eye syndrome	Enrichment	ACTG1	0.58
1073	Meier-gorlin syndrome 1	Enrichment	FGFR2	0.58
1074	Peters-plus syndrome	Enrichment	BMP4	0.58
1075	Amelogenesis imperfecta, type ie	Enrichment	ITGB6	0.58
1076	Stroke, ischemic	Enrichment	PRKCH	0.58
1077	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	0.58
1078	Stickler syndrome	Enrichment	BMP4	0.58
1079	Nemaline myopathy	Enrichment	ACTA1	0.58
1080	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3R1	0.58
1081	Primary bone dysplasia	Enrichment	FGFR3	0.58
1082	Difference of sex development	Enrichment	AR	0.58
1083	Nephrotic syndrome, type 1	Enrichment	PLCE1	0.56
1084	Developmental and epileptic encephalopathy 14	Enrichment	PLCB1	0.56
1085	Frontotemporal dementia 1	Enrichment	CSF1R	0.55
1086	Osteochondrodysplasia	Enrichment	FGFR3	0.55
1087	Ichthyosis	Enrichment	IL2RB	0.55
1088	Familial colorectal cancer type x	Enrichment	BMPR1A	0.55
1089	Cardiomyopathy, familial hypertrophic, 4	Enrichment	NCF1	0.53
1090	Coronary heart disease 5	Enrichment	IKBKG	0.53
1091	Chronic granulomatous disease	Enrichment	NCF1	0.53
1092	Autosomal dominant non-syndromic intellectual disability	Enrichment	ERBB4, GNB1, YWHAZ	0.53
1093	Myasthenic syndrome, congenital, 4c, associated with acetylcholine receptor deficiency	Enrichment	MUSK	0.52
1094	Achromatopsia	Enrichment	GNAT2	0.52
1095	Familial colorectal cancer	Enrichment	TP53	0.52
1096	Epicanthus	Enrichment	ACVR1	0.51
1097	Septooptic dysplasia	Enrichment	FGFR1	0.51
1098	Cutis laxa	Enrichment	LTBP4	0.51
1099	46 xx gonadal dysgenesis	Enrichment	BMP15	0.51
1100	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	TGFB3	0.51
1101	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	TGFB3	0.51
1102	Microcephaly	Enrichment	ACTB, ACTG1, GNB1, IGF1R, PAK3	0.51
1103	Hereditary breast ovarian cancer syndrome	Enrichment	KRAS, RIPK1, TP53	0.51
1104	Polymicrogyria	Enrichment	AKT3	0.49
1105	Melanoma	Enrichment	PTEN	0.49
1106	Neural tube defects	Enrichment	ITGB1	0.49
1107	Amelogenesis imperfecta	Enrichment	LTBP3	0.49
1108	Cerebral palsy	Enrichment	GNB1, PDGFRB	0.49
1109	Migraine with or without aura 1	Enrichment	TAB2	0.49
1110	Pectus excavatum	Enrichment	TGFBR1	0.49
1111	Movement disease	Enrichment	GNAO1	0.49
1112	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	CSF1R, ERBB4, MEF2C	0.47
1113	46,xy complete gonadal dysgenesis	Enrichment	AR	0.46
1114	Uterine corpus cancer	Enrichment	PTEN	0.46
1115	Specific learning disability	Enrichment	YWHAG	0.46
1116	Hypogonadotropic hypogonadism 7 with or without anosmia	Enrichment	FGFR1	0.46
1117	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	TGFB3	0.46
1118	Isolated macular dystrophy	Enrichment	ITGA4	0.46
1119	Postsynaptic congenital myasthenic syndromes	Enrichment	MUSK	0.45
1120	Dystonia	Enrichment	GNAL, GNB1	0.45
1121	Wilms tumor 1	Enrichment	IGF2	0.44
1122	Osteogenesis imperfecta, type iii	Enrichment	BMP1	0.44
1123	Chromosome 1p36 deletion syndrome	Enrichment	PRKCZ	0.43
1124	Protein-deficiency anemia	Enrichment	NRAS	0.43
1125	Fetal akinesia deformation sequence 1	Enrichment	MUSK, ROR2	0.42
1126	Microphthalmia/coloboma 12	Enrichment	YAP1	0.40
1127	Pulmonary disease, chronic obstructive	Enrichment	PDE3B	0.40
1128	Osteoporosis	Enrichment	SRC	0.40
1129	Pheochromocytoma	Enrichment	MAX	0.40
1130	Cone-rod dystrophy 6	Enrichment	GNAT2	0.40
1131	Cataract	Enrichment	EPHA2	0.40
1132	46,xy partial gonadal dysgenesis	Enrichment	SOS1	0.40
1133	Cleft palate, isolated	Enrichment	GNB1	0.39
1134	Dandy-walker syndrome	Enrichment	PDGFRB	0.39
1135	Lynch syndrome	Enrichment	KRAS	0.38
1136	Rare genetic intellectual disability	Enrichment	GNAO1	0.38
1137	Beckwith-wiedemann syndrome	Enrichment	IGF2	0.38
1138	Neuromuscular disease	Enrichment	ACTA1	0.38
1139	Congenital myopathy	Enrichment	ACTA1	0.36
1140	Ehlers-danlos syndrome	Enrichment	TGFB2	0.36
1141	Coloboma of macula	Enrichment	YAP1	0.36
1142	Autosomal dominant polycystic kidney disease	Enrichment	TSC2	0.36
1143	Kidney disease	Enrichment	TSC1	0.36
1144	Body mass index quantitative trait locus 11	Enrichment	BDNF, GNAS	0.35
1145	Epilepsy	Enrichment	GABRA1, GABRB3	0.35
1146	Williams-beuren syndrome	Enrichment	GTF2I	0.34
1147	Macs syndrome	Enrichment	GDF6	0.34
1148	Cataract 44	Enrichment	EPHA2	0.34
1149	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	ACTG1, KITLG	0.33
1150	Lissencephaly	Enrichment	ACTG1	0.33
1151	Centronuclear myopathy	Enrichment	ACTA1	0.33
1152	Patent foramen ovale	Enrichment	TAB2	0.32
1153	Early infantile developmental and epileptic encephalopathy	Enrichment	GNAO1	0.32
1154	Early-onset nuclear cataract	Enrichment	EPHA2	0.32
1155	Attention deficit-hyperactivity disorder	Enrichment	GNB5	0.31
1156	Skin disease	Enrichment	ITGB4	0.31
1157	Brittle bone disorder	Enrichment	BMP1	0.30
1158	Focal segmental glomerulosclerosis	Enrichment	PLCE1	0.29
1159	Hereditary paraganglioma-pheochromocytoma syndromes	Enrichment	MAX	0.27
1160	Brugada syndrome	Enrichment	SEMA3A	0.26
1161	Strabismus	Enrichment	GNB1	0.25
1162	Diamond-blackfan anemia 1	Enrichment	TP53	0.25
1163	Precursor t-cell acute lymphoblastic leukemia	Enrichment	FLT3	0.25
1164	Congenital nervous system abnormality	Enrichment	FGFR3, GNB5, PTEN, TSC2	0.24
1165	Nervous system disease	Enrichment	FGFR3, GNB5, PTEN, TSC2	0.24
1166	Cone dystrophy	Enrichment	GNAT2	0.24
1167	Developmental and epileptic encephalopathy 1	Enrichment	GNAO1	0.23
1168	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	0.22
1169	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	HGF, MET, ROR1	0.21
1170	Cystic fibrosis	Enrichment	TGFB1	0.21
1171	Primary autosomal recessive microcephaly	Enrichment	ANGPT2	0.21
1172	Peripheral nervous system disease	Enrichment	NGF	0.21
1173	Neuropathy	Enrichment	NGF	0.21
1174	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	AR, FGF8	0.20
1175	Non-syndromic genetic deafness	Enrichment	ACTG1	0.18
1176	Myopathy	Enrichment	ACTA1	0.15
1177	Genetic steroid-resistant nephrotic syndrome	Enrichment	PLCE1	0.15
1178	Eye disease	Enrichment	GNAT2	0.14
1179	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.14
1180	Distal arthrogryposis	Enrichment	ACTA1	0.14
1181	Nonsyndromic hearing loss	Enrichment	ACTG1	0.14
1182	Complex neurodevelopmental disorder	Enrichment	GNB2, PAK3, RAC3	0.14
1183	Developmental and epileptic encephalopathy	Enrichment	GNAO1	0.14
1184	Diamond-blackfan anemia	Enrichment	TP53	0.14
1185	Nephrotic syndrome	Enrichment	ITGA3	0.14
1186	Male infertility	Enrichment	AR	0.14
1187	Left ventricular noncompaction	Enrichment	RAF1	0.13
1188	Sensorineural hearing loss	Enrichment	HGF	0.11
1189	Charcot-marie-tooth disease	Enrichment	HSPB1	0.11
1190	Benign epilepsy with centrotemporal spikes	Enrichment	PLCB1	0.11
1191	Autism spectrum disorder	Enrichment	GNB1, PTEN, TSC2	0.10
1192	Centralopathic epilepsy	Enrichment	PLCB1	0.10
1193	Hypertelorism	Enrichment	FGFR2	0.10
1194	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	0.06
1195	Cone-rod dystrophy 2	Enrichment	ITGA4	0.06
1196	Schizophrenia	Enrichment	GABRB2	0.05
1197	Primary ciliary dyskinesia	Enrichment	DRC4	0.05
1198	Rare genetic deafness	Enrichment	ACTG1	0.04
1199	Dilated cardiomyopathy	Enrichment	ACTA1	0.04
1200	Mitochondrial disease	Enrichment	GFER	0.03
1201	Leber plus disease	Enrichment	GDF6	0.02
1202	Hereditary retinal dystrophy	Enrichment	GNAT1, GNAT2, MERTK, TIMP3	0.00
1203	Fundus dystrophy	Enrichment	GNAT1, GNAT2, MERTK, TIMP3	0.00
1204	Retinitis pigmentosa	Enrichment	GNAT1, MERTK	0.00

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Akt Signaling

Pathway Network for Akt Signaling

Pathway network for the Akt Signaling SuperPath

Member Pathways for Akt Signaling

Pathways in the Akt Signaling SuperPath

Gene overlap in member pathways for Akt Signaling SuperPath

Associated Genes for Akt Signaling

Associated Disorders for Akt Signaling

Disorders associated with Akt Signaling SuperPath

STRING Interaction Network for Akt Signaling

Sources for Akt Signaling