Alanine and aspartate metabolism

No Pathway Network information available for Alanine and aspartate metabolism

#	Name	Source	Genes
1	Alanine and aspartate metabolism	WikiPathways	ABAT AGXT ASL ASPA ASS1 DARS1 GAD1 GAD2 GOT1 GOT2 GPT PC (see all 12) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PC	Pyruvate Carboxylase	Protein Coding	1
2	ASS1	Argininosuccinate Synthase 1	Protein Coding	1
3	ASPA	Aspartoacylase	Protein Coding	1
4	ASL	Argininosuccinate Lyase	Protein Coding	1
5	GPT	Glutamic--Pyruvic Transaminase	Protein Coding	1
6	GOT1	Glutamic-Oxaloacetic Transaminase 1	Protein Coding	1
7	GAD2	Glutamate Decarboxylase 2	Protein Coding	1
8	GAD1	Glutamate Decarboxylase 1	Protein Coding	1
9	AGXT	Alanine--Glyoxylate Aminotransferase	Protein Coding	1
10	ABAT	4-Aminobutyrate Aminotransferase	Protein Coding	1
11	DARS1	Aspartyl-TRNA Synthetase 1	Protein Coding	1
12	GOT2	Glutamic-Oxaloacetic Transaminase 2	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Argininosuccinic aciduria	Enrichment	ASL	3.05
2	Hyperoxaluria, primary, type i	Enrichment	AGXT	3.05
3	Developmental and epileptic encephalopathy 89	Enrichment	GAD1	3.05
4	Gaba aminotransferase deficiency	Enrichment	ABAT	3.05
5	Gaba-transaminase deficiency	Enrichment	ABAT	3.05
6	Aspartate aminotransferase, serum level of, quantitative trait locus 1	Enrichment	GOT1	3.05
7	Hypomyelination with brainstem and spinal cord involvement and leg spasticity	Enrichment	DARS1	3.05
8	Citrullinemia, classic	Enrichment	ASS1	2.75
9	Canavan disease	Enrichment	ASPA	2.75
10	Developmental and epileptic encephalopathy 82	Enrichment	GOT2	2.75
11	Citrullinemia	Enrichment	ASS1	2.75
12	Primary hyperoxaluria	Enrichment	AGXT	2.75
13	Pyruvate carboxylase deficiency	Enrichment	PC	2.58
14	Citrin deficiency, adolescent or adult onset	Enrichment	ASS1	2.58
15	Glycogen storage disease ia	Enrichment	ASS1	2.45
16	Neurodevelopmental disorder with progressive spasticity and brain white matter abnormalities	Enrichment	GAD1	2.45
17	Spastic quadriplegic cerebral palsy	Enrichment	GAD1	2.45
18	Myasthenic syndrome, congenital, 4c, associated with acetylcholine receptor deficiency	Enrichment	ASL	2.05
19	Nephrocalcinosis	Enrichment	AGXT	2.05
20	Nephrolithiasis	Enrichment	AGXT	2.05
21	Developmental and epileptic encephalopathy	Enrichment	GOT2	1.50
22	Nephrotic syndrome	Enrichment	AGXT	1.43
23	Autism	Enrichment	ASPA	1.21

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Alanine and aspartate metabolism