ALK2 signaling events

No Pathway Network information available for ALK2 signaling events

Pathways in the ALK2 signaling events SuperPath

#	Name	Source	Genes
1	ALK2 signaling events	PubChem	ACVR1 AMH AMHR2 BMP7 BMPR2 FKBP1A SMAD1 SMAD4 TLX2 (see all 9) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	TLX2	T Cell Leukemia Homeobox 2	Protein Coding	1
2	ACVR1	Activin A Receptor Type 1	Protein Coding	1
3	BMPR2	Bone Morphogenetic Protein Receptor Type 2	Protein Coding	1
4	BMP7	Bone Morphogenetic Protein 7	Protein Coding	1
5	SMAD1	SMAD Family Member 1	Protein Coding	1
6	AMH	Anti-Mullerian Hormone	Protein Coding	1
7	AMHR2	Anti-Mullerian Hormone Receptor Type 2	Protein Coding	1
8	FKBP1A	FKBP Prolyl Isomerase 1A	Protein Coding	1
9	SMAD4	SMAD Family Member 4	Protein Coding	1

Disorders associated with ALK2 signaling events SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Fibrodysplasia ossificans progressiva	Enrichment	ACVR1, BMPR2	6.41
2	Persistent mullerian duct syndrome, types i and ii	Enrichment	AMH, AMHR2	5.63
3	Persistent mullerian duct syndrome	Enrichment	AMH, AMHR2	5.63
4	Heritable thoracic aortic disease	Enrichment	SMAD4	3.18
5	Primary pulmonary hypertension	Enrichment	BMPR2	3.18
6	Pulmonary hypertension	Enrichment	BMPR2	3.18
7	Drug- or toxin-induced pulmonary arterial hypertension	Enrichment	BMPR2	3.18
8	Myhre syndrome	Enrichment	SMAD4	2.88
9	Pulmonary venoocclusive disease 1, autosomal dominant	Enrichment	BMPR2	2.88
10	Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome	Enrichment	SMAD4	2.88
11	Pulmonary venoocclusive disease 1	Enrichment	BMPR2	2.88
12	Pulmonary venoocclusive disease	Enrichment	BMPR2	2.88
13	Idiopathic/heritable pulmonary arterial hypertension	Enrichment	BMPR2	2.88
14	Juvenile polyposis syndrome	Enrichment	SMAD4	2.70
15	Pulmonary arterial hypertension associated with congenital heart disease	Enrichment	BMPR2	2.70
16	Ventricular septal defect 1	Enrichment	BMP7	2.48
17	Congenital heart defects, multiple types, 4	Enrichment	BMP7	2.48
18	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	SMAD4	2.48
19	Gallbladder cancer	Enrichment	SMAD4	2.33
20	Hereditary hemorrhagic telangiectasia	Enrichment	SMAD4	2.33
21	Tooth agenesis, selective, 1	Enrichment	BMPR2	2.22
22	Heritable pulmonary arterial hypertension	Enrichment	BMPR2	2.14
23	Epicanthus	Enrichment	ACVR1	2.10
24	Pulmonary hypertension, primary, 1	Enrichment	BMPR2	2.07
25	Pancreatic cancer	Enrichment	SMAD4	1.78
26	Gastric cancer	Enrichment	SMAD4	1.55
27	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	SMAD4	1.54
28	Thrombocytopenia	Enrichment	SMAD4	1.50
29	Colorectal cancer	Enrichment	SMAD4	1.25
30	Inherited cancer-predisposing syndrome	Enrichment	SMAD4	1.07

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

ALK2 signaling events

Pathway Network for ALK2 signaling events

Member Pathways for ALK2 signaling events

Pathways in the ALK2 signaling events SuperPath

Associated Genes for ALK2 signaling events

Associated Disorders for ALK2 signaling events

Disorders associated with ALK2 signaling events SuperPath

STRING Interaction Network for ALK2 signaling events

Sources for ALK2 signaling events