Allopurinol Pathway, Pharmacokinetics
Pathways in the Allopurinol Pathway, Pharmacokinetics SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Allopurinol Pathway, Pharmacokinetics | PharmGKB |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | XDH | Xanthine Dehydrogenase | Protein Coding | 1 |
| 2 | PNP | Purine Nucleoside Phosphorylase | Protein Coding | 1 |
| 3 | AOX1 | Aldehyde Oxidase 1 | Protein Coding | 1 |
| 4 | HPRT1 | Hypoxanthine Phosphoribosyltransferase 1 | Protein Coding | 1 |
| 5 | SLC22A11 | Solute Carrier Family 22 Member 11 | Protein Coding | 1 |
| 6 | SLC22A12 | Solute Carrier Family 22 Member 12 | Protein Coding | 1 |
| 7 | MOCOS | Molybdenum Cofactor Sulfurase | Protein Coding | 1 |
Disorders associated with Allopurinol Pathway, Pharmacokinetics SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Xanthinuria, type ii | Enrichment | MOCOS, XDH | 6.16 |
| 2 | Hypouricemia, renal, 1 | Enrichment | SLC22A12 | 3.29 |
| 3 | Purine nucleoside phosphorylase deficiency | Enrichment | PNP | 3.29 |
| 4 | Xanthinuria, type i | Enrichment | XDH | 2.99 |
| 5 | Familial renal hypouricemia | Enrichment | SLC22A12 | 2.99 |
| 6 | Lesch-nyhan syndrome | Enrichment | HPRT1 | 2.81 |
| 7 | Hyperuricemia, hprt-related | Enrichment | HPRT1 | 2.81 |
| 8 | Severe combined immunodeficiency | Enrichment | PNP | 1.77 |
| 9 | Autism spectrum disorder | Enrichment | MOCOS | 1.26 |
