Alzheimer's disease and miRNA effects

No Pathway Network information available for Alzheimer's disease and miRNA effects

Pathways in the Alzheimer's disease and miRNA effects SuperPath

#	Name	Source	Genes
1	Alzheimer's disease and miRNA effects	WikiPathways	ADAM10 ADAM17 ADRM1 AGER AKT1 AKT2 AKT3 AMBRA1 APAF1 APBB1 APC APC2 APH1A APH1B APOE APP ARAF ATF4 ATF6 ATG101 ATG13 ATG14 ATG2A ATG2B ATP2A1 ATP2A2 ATP2A3 AXIN1 AXIN2 BACE1 BAD BECN1 BECN2 BID BRAF CACNA1C-IT2 CACNA1D CACNA1F CACNA1S CALM1 CALM2 CALM3 CALML3 CALML4 CALML5 CALML6 CAPN1 CAPN2 CASP12 CASP3 CASP7 CASP8 CASP9 CDK5 CDK5R1 CHRNA7 CHUK CSF1 CSNK1A1 CSNK1A1L CSNK1E CSNK2A1 CSNK2A2 CSNK2A3 CSNK2B CTNNB1 CYBB CYCS DDIT3 DKK1 DKK2 DKK4 DVL1 DVL2 DVL3 EIF2AK2 EIF2AK3 EIF2S1 ERN1 FADD FAS FRAT1 FRAT2 FZD1 FZD10 FZD2 FZD3 FZD5 FZD6 FZD7 FZD8 FZD9 GAPDH GNAQ GPR83 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GSK3B HRAS HSD17B10 IDE IKBKB IL1A IL1B IL6 INS INSR IRS1 IRS2 IRS4 ITPR1 ITPR2 ITPR3 KIF5A KIF5B KIF5C KLC1 KLC2 KLC3 KLC4 KRAS LOC105372522 LPL LRP1 LRP5 LRP6 MAP2K1 MAP2K2 MAP2K7 MAP3K5 MAPK1 MAPK10 MAPK3 MAPK8 MAPK9 MAPT MCU MIR101-1 MIR132 MIR29A MIR29B1 MIR29C MME MTOR NAE1 NCSTN NFKB1 NOS1 NOS2 NOX1 NOX4 NRAS NRBF2 PIK3C3 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 PLCB2 PLCB3 PLCB4 PPID PPIF PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PSEN1 PSEN2 PSENEN PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PTGS2 RAF1 RB1CC1 RELA RTN3 RTN4 RYR3 SEM1 SFRP4 SLC25A31 SLC25A4 SLC25A5 SLC25A6 SNCA TNF TNFRSF1A TRAF2 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3D TUBA3E TUBA4A TUBA8 TUBAL3 TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 ULK1 ULK2 VDAC1 VDAC2 VDAC3 WIPI1 WIPI2 WNT1 WNT10A WNT10B WNT11 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B XBP1 (see all 267) (see less)
2	Alzheimer's disease	WikiPathways	ADAM10 ADAM17 ADRM1 AGER AKT1 AKT2 AKT3 AMBRA1 APAF1 APBB1 APC APC2 APH1A APH1B APOE APP ARAF ATF4 ATF6 ATG101 ATG13 ATG14 ATG2A ATG2B ATP2A1 ATP2A2 ATP2A3 AXIN1 AXIN2 BACE1 BAD BECN1 BECN2 BID BRAF CACNA1C-IT2 CACNA1D CACNA1F CACNA1S CALM1 CALM2 CALM3 CALML3 CALML4 CALML5 CALML6 CAPN1 CAPN2 CASP12 CASP3 CASP7 CASP8 CASP9 CDK5 CDK5R1 CHRNA7 CHUK CSF1 CSNK1A1 CSNK1A1L CSNK1E CSNK2A1 CSNK2A2 CSNK2A3 CSNK2B CTNNB1 CYBB CYCS DDIT3 DKK1 DKK2 DKK4 DVL1 DVL2 DVL3 EIF2AK2 EIF2AK3 EIF2S1 ERN1 FADD FAS FRAT1 FRAT2 FZD1 FZD10 FZD2 FZD3 FZD5 FZD6 FZD7 FZD8 FZD9 GAPDH GNAQ GPR83 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GSK3B HRAS HSD17B10 IDE IKBKB IL1A IL1B IL6 INS INSR IRS1 IRS2 IRS4 ITPR1 ITPR2 ITPR3 KIF5A KIF5B KIF5C KLC1 KLC2 KLC3 KLC4 KRAS LOC105372522 LPL LRP1 LRP5 LRP6 MAP2K1 MAP2K2 MAP2K7 MAP3K5 MAPK1 MAPK10 MAPK3 MAPK8 MAPK9 MAPT MCU MME MTOR NAE1 NCSTN NFKB1 NOS1 NOS2 NOX1 NOX4 NRAS NRBF2 PIK3C3 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PIK3R4 PLCB2 PLCB3 PLCB4 PPID PPIF PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PSEN1 PSEN2 PSENEN PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PTGS2 RAF1 RB1CC1 RELA RTN3 RTN4 RYR3 SEM1 SFRP4 SLC25A31 SLC25A4 SLC25A5 SLC25A6 SNCA TNF TNFRSF1A TRAF2 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3D TUBA3E TUBA4A TUBA8 TUBAL3 TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 ULK1 ULK2 VDAC1 VDAC2 VDAC3 WIPI1 WIPI2 WNT1 WNT10A WNT10B WNT11 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B XBP1 (see all 262) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	AGER	Advanced Glycosylation End-Product Specific Receptor	Protein Coding	2
2	TUBAL3	Tubulin Alpha Like 3	Protein Coding	2
3	TUBA3C	Tubulin Alpha 3c	Protein Coding	2
4	PLCB3	Phospholipase C Beta 3	Protein Coding	2
5	PLCB2	Phospholipase C Beta 2	Protein Coding	2
6	PIK3C3	Phosphatidylinositol 3-Kinase Catalytic Subunit Type 3	Protein Coding	2
7	TUBA3D	Tubulin Alpha 3d	Protein Coding	2
8	TUBA3E	Tubulin Alpha 3e	Protein Coding	2
9	PSMD6	Proteasome 26S Subunit, Non-ATPase 6	Protein Coding	2
10	RB1CC1	RB1 Inducible Coiled-Coil 1	Protein Coding	2
11	ULK2	Unc-51 Like Autophagy Activating Kinase 2	Protein Coding	2
12	EIF2AK3	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3	Protein Coding	2
13	WNT3A	Wnt Family Member 3A	Protein Coding	2
14	CDK5R1	Cyclin Dependent Kinase 5 Regulatory Subunit 1	Protein Coding	2
15	FADD	Fas Associated Via Death Domain	Protein Coding	2
16	BECN1	Beclin 1	Protein Coding	2
17	IRS2	Insulin Receptor Substrate 2	Protein Coding	2
18	TUBA1C	Tubulin Alpha 1c	Protein Coding	2
19	IRS4	Insulin Receptor Substrate 4	Protein Coding	2
20	TUBB6	Tubulin Beta 6 Class V	Protein Coding	2
21	CASP9	Caspase 9	Protein Coding	2
22	CASP8	Caspase 8	Protein Coding	2
23	CASP7	Caspase 7	Protein Coding	2
24	CASP3	Caspase 3	Protein Coding	2
25	APH1B	Aph-1B Gamma-Secretase Subunit	Protein Coding	2
26	FZD8	Frizzled Class Receptor 8	Protein Coding	2
27	FZD6	Frizzled Class Receptor 6	Protein Coding	2
28	AXIN2	Axin 2	Protein Coding	2
29	AXIN1	Axin 1	Protein Coding	2
30	CAPN2	Calpain 2	Protein Coding	2
31	CAPN1	Calpain 1	Protein Coding	2
32	WNT5B	Wnt Family Member 5B	Protein Coding	2
33	TUBB1	Tubulin Beta 1 Class VI	Protein Coding	2
34	CALML3	Calmodulin Like 3	Protein Coding	2
35	CALM2	Calmodulin 2	Protein Coding	2
36	WNT10A	Wnt Family Member 10A	Protein Coding	2
37	CALM1	Calmodulin 1	Protein Coding	2
38	SEM1	SEM1 26S Proteasome Subunit	Protein Coding	2
39	TUBA1A	Tubulin Alpha 1a	Protein Coding	2
40	CACNA1S	Calcium Voltage-Gated Channel Subunit Alpha1 S	Protein Coding	2
41	CACNA1F	Calcium Voltage-Gated Channel Subunit Alpha1 F	Protein Coding	2
42	CACNA1D	Calcium Voltage-Gated Channel Subunit Alpha1 D	Protein Coding	2
43	XBP1	X-Box Binding Protein 1	Protein Coding	2
44	WNT2B	Wnt Family Member 2B	Protein Coding	2
45	WNT11	Wnt Family Member 11	Protein Coding	2
46	WNT10B	Wnt Family Member 10B	Protein Coding	2
47	WNT7A	Wnt Family Member 7A	Protein Coding	2
48	WNT5A	Wnt Family Member 5A	Protein Coding	2
49	WNT3	Wnt Family Member 3	Protein Coding	2
50	WNT2	Wnt Family Member 2	Protein Coding	2
51	WNT1	Wnt Family Member 1	Protein Coding	2
52	VDAC2	Voltage Dependent Anion Channel 2	Protein Coding	2
53	VDAC1	Voltage Dependent Anion Channel 1	Protein Coding	2
54	TUBB2A	Tubulin Beta 2A Class IIa	Protein Coding	2
55	TUBA4A	Tubulin Alpha 4a	Protein Coding	2
56	TNFRSF1A	TNF Receptor Superfamily Member 1A	Protein Coding	2
57	TNF	Tumor Necrosis Factor	Protein Coding	2
58	ADAM17	ADAM Metallopeptidase Domain 17	Protein Coding	2
59	BRAF	B-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	2
60	SNCA	Synuclein Alpha	Protein Coding	2
61	KLC2	Kinesin Light Chain 2	Protein Coding	2
62	SFRP4	Secreted Frizzled Related Protein 4	Protein Coding	2
63	BID	BH3 Interacting Domain Death Agonist	Protein Coding	2
64	ATG101	Autophagy Related 101	Protein Coding	2
65	RELA	RELA Proto-Oncogene, NF-KB Subunit	Protein Coding	2
66	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	2
67	PTGS2	Prostaglandin-Endoperoxide Synthase 2	Protein Coding	2
68	BAD	BCL2 Associated Agonist Of Cell Death	Protein Coding	2
69	PSMD13	Proteasome 26S Subunit, Non-ATPase 13	Protein Coding	2
70	PSMD12	Proteasome 26S Subunit, Non-ATPase 12	Protein Coding	2
71	RTN4	Reticulon 4	Protein Coding	2
72	PSMD8	Proteasome 26S Subunit, Non-ATPase 8	Protein Coding	2
73	PSMD3	Proteasome 26S Subunit, Non-ATPase 3	Protein Coding	2
74	PSMC5	Proteasome 26S Subunit, ATPase 5	Protein Coding	2
75	PSMC3	Proteasome 26S Subunit, ATPase 3	Protein Coding	2
76	PSMB7	Proteasome 20S Subunit Beta 7	Protein Coding	2
77	PSMB5	Proteasome 20S Subunit Beta 5	Protein Coding	2
78	PSMB4	Proteasome 20S Subunit Beta 4	Protein Coding	2
79	PSMB2	Proteasome 20S Subunit Beta 2	Protein Coding	2
80	PSMB1	Proteasome 20S Subunit Beta 1	Protein Coding	2
81	PSMA6	Proteasome 20S Subunit Alpha 6	Protein Coding	2
82	PSMA5	Proteasome 20S Subunit Alpha 5	Protein Coding	2
83	PSMA4	Proteasome 20S Subunit Alpha 4	Protein Coding	2
84	PSMA2	Proteasome 20S Subunit Alpha 2	Protein Coding	2
85	PSEN2	Presenilin 2	Protein Coding	2
86	PSEN1	Presenilin 1	Protein Coding	2
87	EIF2AK2	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2	Protein Coding	2
88	MAP2K7	Mitogen-Activated Protein Kinase Kinase 7	Protein Coding	2
89	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	2
90	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	2
91	MAPK10	Mitogen-Activated Protein Kinase 10	Protein Coding	2
92	MAPK9	Mitogen-Activated Protein Kinase 9	Protein Coding	2
93	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	2
94	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	2
95	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	2
96	PSENEN	Presenilin Enhancer, Gamma-Secretase Subunit	Protein Coding	2
97	AMBRA1	Autophagy And Beclin 1 Regulator 1	Protein Coding	2
98	PPP3R1	Protein Phosphatase 3 Regulatory Subunit B, Alpha	Protein Coding	2
99	PPP3CC	Protein Phosphatase 3 Catalytic Subunit Gamma	Protein Coding	2
100	PPP3CB	Protein Phosphatase 3 Catalytic Subunit Beta	Protein Coding	2
101	PPP3CA	Protein Phosphatase 3 Catalytic Subunit Alpha	Protein Coding	2
102	ATG2B	Autophagy Related 2B	Protein Coding	2
103	WIPI1	WD Repeat Domain, Phosphoinositide Interacting 1	Protein Coding	2
104	WNT4	Wnt Family Member 4	Protein Coding	2
105	CYCS	Cytochrome C, Somatic	Protein Coding	2
106	PLCB4	Phospholipase C Beta 4	Protein Coding	2
107	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	2
108	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	2
109	PIK3CD	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta	Protein Coding	2
110	PIK3CB	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta	Protein Coding	2
111	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	2
112	TUBA8	Tubulin Alpha 8	Protein Coding	2
113	NOX4	NADPH Oxidase 4	Protein Coding	2
114	NRAS	NRAS Proto-Oncogene, GTPase	Protein Coding	2
115	ATP2A3	ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 3	Protein Coding	2
116	ATP2A2	ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 2	Protein Coding	2
117	ATP2A1	ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 1	Protein Coding	2
118	NOS2	Nitric Oxide Synthase 2	Protein Coding	2
119	NOS1	Nitric Oxide Synthase 1	Protein Coding	2
120	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	2
121	ATF4	Activating Transcription Factor 4	Protein Coding	2
122	MME	Membrane Metalloendopeptidase	Protein Coding	2
123	MAP3K5	Mitogen-Activated Protein Kinase Kinase Kinase 5	Protein Coding	2
124	MAPT	Microtubule Associated Protein Tau	Protein Coding	2
125	LRP5	LDL Receptor Related Protein 5	Protein Coding	2
126	LRP6	LDL Receptor Related Protein 6	Protein Coding	2
127	LRP1	LDL Receptor Related Protein 1	Protein Coding	2
128	LPL	Lipoprotein Lipase	Protein Coding	2
129	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	2
130	KIF5C	Kinesin Family Member 5C	Protein Coding	2
131	KIF5B	Kinesin Family Member 5B	Protein Coding	2
132	KIF5A	Kinesin Family Member 5A	Protein Coding	2
133	ITPR3	Inositol 1,4,5-Trisphosphate Receptor Type 3	Protein Coding	2
134	ITPR2	Inositol 1,4,5-Trisphosphate Receptor Type 2	Protein Coding	2
135	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	2
136	ARAF	A-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	2
137	IRS1	Insulin Receptor Substrate 1	Protein Coding	2
138	INSR	Insulin Receptor	Protein Coding	2
139	INS	Insulin	Protein Coding	2
140	IL6	Interleukin 6	Protein Coding	2
141	IL1B	Interleukin 1 Beta	Protein Coding	2
142	IL1A	Interleukin 1 Alpha	Protein Coding	2
143	IKBKB	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Beta	Protein Coding	2
144	FAS	Fas Cell Surface Death Receptor	Protein Coding	2
145	APP	Amyloid Beta Precursor Protein	Protein Coding	2
146	APOE	Apolipoprotein E	Protein Coding	2
147	TUBB2B	Tubulin Beta 2B Class IIb	Protein Coding	2
148	TUBB8	Tubulin Beta 8 Class VIII	Protein Coding	2
149	IDE	Insulin Degrading Enzyme	Protein Coding	2
150	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	2
151	APC	APC Regulator Of Wnt Signaling Pathway	Protein Coding	2
152	APAF1	Apoptotic Peptidase Activating Factor 1	Protein Coding	2
153	HSD17B10	Hydroxysteroid 17-Beta Dehydrogenase 10	Protein Coding	2
154	GSK3B	Glycogen Synthase Kinase 3 Beta	Protein Coding	2
155	SLC25A4	Solute Carrier Family 25 Member 4	Protein Coding	2
156	GRIN2D	Glutamate Ionotropic Receptor NMDA Type Subunit 2D	Protein Coding	2
157	GRIN2B	Glutamate Ionotropic Receptor NMDA Type Subunit 2B	Protein Coding	2
158	GRIN2A	Glutamate Ionotropic Receptor NMDA Type Subunit 2A	Protein Coding	2
159	GRIN1	Glutamate Ionotropic Receptor NMDA Type Subunit 1	Protein Coding	2
160	GNAQ	G Protein Subunit Alpha Q	Protein Coding	2
161	NOX1	NADPH Oxidase 1	Protein Coding	2
162	GAPDH	Glyceraldehyde-3-Phosphate Dehydrogenase	Protein Coding	2
163	FZD2	Frizzled Class Receptor 2	Protein Coding	2
164	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	2
165	BACE1	Beta-Secretase 1	Protein Coding	2
166	NCSTN	Nicastrin	Protein Coding	2
167	DKK1	Dickkopf Wnt Signaling Pathway Inhibitor 1	Protein Coding	2
168	ATF6	Activating Transcription Factor 6	Protein Coding	2
169	ERN1	Endoplasmic Reticulum To Nucleus Signaling 1	Protein Coding	2
170	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	2
171	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	2
172	TUBB	Tubulin Beta Class I	Protein Coding	2
173	EIF2S1	Eukaryotic Translation Initiation Factor 2 Subunit Alpha	Protein Coding	2
174	DVL3	Dishevelled Segment Polarity Protein 3	Protein Coding	2
175	DVL1	Dishevelled Segment Polarity Protein 1	Protein Coding	2
176	DDIT3	DNA Damage Inducible Transcript 3	Protein Coding	2
177	CYBB	Cytochrome B-245 Beta Chain	Protein Coding	2
178	CTNNB1	Catenin Beta 1	Protein Coding	2
179	CSNK2B	Casein Kinase 2 Beta	Protein Coding	2
180	CSNK2A2	Casein Kinase 2 Alpha 2	Protein Coding	2
181	CSNK2A1	Casein Kinase 2 Alpha 1	Protein Coding	2
182	CSNK1A1	Casein Kinase 1 Alpha 1	Protein Coding	2
183	CSF1	Colony Stimulating Factor 1	Protein Coding	2
184	CHUK	Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex	Protein Coding	2
185	CHRNA7	Cholinergic Receptor Nicotinic Alpha 7 Subunit	Protein Coding	2
186	TUBB4B	Tubulin Beta 4B Class IVb	Protein Coding	2
187	TUBB4A	Tubulin Beta 4A Class IVa	Protein Coding	2
188	TUBB3	Tubulin Beta 3 Class III	Protein Coding	2
189	TUBA1B	Tubulin Alpha 1b	Protein Coding	2
190	APC2	APC Regulator Of Wnt Signaling Pathway 2	Protein Coding	2
191	PSMD14	Proteasome 26S Subunit, Non-ATPase 14	Protein Coding	2
192	CDK5	Cyclin Dependent Kinase 5	Protein Coding	2
193	ADAM10	ADAM Metallopeptidase Domain 10	Protein Coding	2
194	PPIF	Peptidylprolyl Isomerase F	Protein Coding	2
195	CASP12	Caspase 12 (Gene/Pseudogene)	Protein Coding	2
196	AKT3	AKT Serine/Threonine Kinase 3	Protein Coding	2
197	DVL2	Dishevelled Segment Polarity Protein 2	Protein Coding	2
198	CALML6	Calmodulin Like 6	Protein Coding	2
199	KLC3	Kinesin Light Chain 3	Protein Coding	2
200	ATG13	Autophagy Related 13	Protein Coding	2
201	CALML4	Calmodulin Like 4	Protein Coding	2
202	MCU	Mitochondrial Calcium Uniporter	Protein Coding	2
203	KLC4	Kinesin Light Chain 4	Protein Coding	2
204	NAE1	NEDD8 Activating Enzyme E1 Subunit 1	Protein Coding	2
205	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	2
206	ULK1	Unc-51 Like Autophagy Activating Kinase 1	Protein Coding	2
207	CSNK1E	Casein Kinase 1 Epsilon	Protein Coding	2
208	PSMA8	Proteasome 20S Subunit Alpha 8	Protein Coding	2
209	CSNK1A1L	Casein Kinase 1 Alpha 1 Like	Protein Coding	2
210	FZD10	Frizzled Class Receptor 10	Protein Coding	2
211	ADRM1	ADRM1 26S Proteasome Ubiquitin Receptor	Protein Coding	2
212	GPR83	G Protein-Coupled Receptor 83	Protein Coding	2
213	LOC105372522	Uncharacterized LOC105372522	RNA Gene	2
214	RTN3	Reticulon 3	Protein Coding	2
215	CACNA1C-IT2	CACNA1C Intronic Transcript 2	RNA Gene	2
216	SLC25A31	Solute Carrier Family 25 Member 31	Protein Coding	2
217	FZD9	Frizzled Class Receptor 9	Protein Coding	2
218	FZD7	Frizzled Class Receptor 7	Protein Coding	2
219	FZD1	Frizzled Class Receptor 1	Protein Coding	2
220	CALM3	Calmodulin 3	Protein Coding	2
221	FZD3	Frizzled Class Receptor 3	Protein Coding	2
222	FZD5	Frizzled Class Receptor 5	Protein Coding	2
223	WNT7B	Wnt Family Member 7B	Protein Coding	2
224	WNT6	Wnt Family Member 6	Protein Coding	2
225	VDAC3	Voltage Dependent Anion Channel 3	Protein Coding	2
226	TRAF2	TNF Receptor Associated Factor 2	Protein Coding	2
227	RYR3	Ryanodine Receptor 3	Protein Coding	2
228	PSMD9	Proteasome 26S Subunit, Non-ATPase 9	Protein Coding	2
229	PSMD7	Proteasome 26S Subunit, Non-ATPase 7	Protein Coding	2
230	PSMD4	Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 4	Protein Coding	2
231	PSMD2	Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 2	Protein Coding	2
232	PSMD1	Proteasome 26S Subunit, Non-ATPase 1	Protein Coding	2
233	PSMC6	Proteasome 26S Subunit, ATPase 6	Protein Coding	2
234	PSMC4	Proteasome 26S Subunit, ATPase 4	Protein Coding	2
235	PSMC2	Proteasome 26S Subunit, ATPase 2	Protein Coding	2
236	PSMC1	Proteasome 26S Subunit, ATPase 1	Protein Coding	2
237	PSMB6	Proteasome 20S Subunit Beta 6	Protein Coding	2
238	PSMB3	Proteasome 20S Subunit Beta 3	Protein Coding	2
239	PSMA7	Proteasome 20S Subunit Alpha 7	Protein Coding	2
240	PSMA3	Proteasome 20S Subunit Alpha 3	Protein Coding	2
241	PSMA1	Proteasome 20S Subunit Alpha 1	Protein Coding	2
242	PPP3R2	Protein Phosphatase 3 Regulatory Subunit B, Beta	Protein Coding	2
243	PPID	Peptidylprolyl Isomerase D	Protein Coding	2
244	CALML5	Calmodulin Like 5	Protein Coding	2
245	WNT16	Wnt Family Member 16	Protein Coding	2
246	APH1A	Aph-1A Gamma-Secretase Subunit	Protein Coding	2
247	BECN2	Beclin 2	Protein Coding	2
248	KLC1	Kinesin Light Chain 1	Protein Coding	2
249	APBB1	Amyloid Beta Precursor Protein Binding Family B Member 1	Protein Coding	2
250	PIK3R4	Phosphoinositide-3-Kinase Regulatory Subunit 4	Protein Coding	2
251	NRBF2	Nuclear Receptor Binding Factor 2	Protein Coding	2
252	SLC25A6	Solute Carrier Family 25 Member 6	Protein Coding	2
253	SLC25A5	Solute Carrier Family 25 Member 5	Protein Coding	2
254	GRIN2C	Glutamate Ionotropic Receptor NMDA Type Subunit 2C	Protein Coding	2
255	CSNK2A3	Casein Kinase 2 Alpha 3	Protein Coding	2
256	DKK2	Dickkopf Wnt Signaling Pathway Inhibitor 2	Protein Coding	2
257	DKK4	Dickkopf Wnt Signaling Pathway Inhibitor 4	Protein Coding	2
258	WIPI2	WD Repeat Domain, Phosphoinositide Interacting 2	Protein Coding	2
259	FRAT2	FRAT Regulator Of Wnt Signaling Pathway 2	Protein Coding	2
260	ATG2A	Autophagy Related 2A	Protein Coding	2
261	ATG14	Autophagy Related 14	Protein Coding	2
262	FRAT1	FRAT Regulator Of Wnt Signaling Pathway 1	Protein Coding	2
263	MIR29C	MicroRNA 29c	RNA Gene	1
264	MIR29A	MicroRNA 29a	RNA Gene	1
265	MIR132	MicroRNA 132	RNA Gene	1
266	MIR101-1	MicroRNA 101-1	RNA Gene	1
267	MIR29B1	MicroRNA 29b-1	RNA Gene	1

Disorders associated with Alzheimer's disease and miRNA effects SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Noonan syndrome and noonan-related syndrome	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NRAS, RAF1	8.28
2	Lung non-small cell carcinoma	Enrichment	BRAF, HRAS, KRAS, MAP2K1, NRAS, PIK3CA	7.68
3	Cardiofaciocutaneous syndrome 1	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	6.87
4	Robinow syndrome, autosomal dominant 1	Enrichment	DVL1, DVL3, FZD2, WNT5A	6.87
5	Cardiofaciocutaneous syndrome	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	6.87
6	Autosomal dominant robinow syndrome	Enrichment	DVL1, DVL3, FZD2, WNT5A	6.87
7	Noonan syndrome 1	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NRAS, RAF1	6.76
8	Rasopathy	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NRAS, RAF1	6.35
9	Robinow syndrome, autosomal recessive 1	Enrichment	DVL1, DVL3, FZD2, WNT5A	6.17
10	Autosomal recessive robinow syndrome	Enrichment	DVL1, DVL3, FZD2, WNT5A	5.70
11	Breast adenocarcinoma	Enrichment	AKT1, KRAS, PIK3CA, RB1CC1	5.70
12	Alzheimer's disease	Enrichment	APOE, APP, MAPT, PSEN1, TNF	5.53
13	Nevus, epidermal	Enrichment	HRAS, KRAS, NRAS, PIK3CA	5.34
14	Gallbladder cancer	Enrichment	BRAF, CTNNB1, KRAS, PIK3CA	5.34
15	Langerhans cell histiocytosis	Enrichment	BRAF, MAP2K1, NRAS	5.15
16	Osteoporosis, juvenile	Enrichment	DKK1, WNT1, WNT3A	5.15
17	Alzheimer disease 4	Enrichment	APOE, PSEN1, PSEN2	5.15
18	Tubulinopathy-associated dysgyria	Enrichment	TUBA1A, TUBB2B, TUBB3	5.15
19	Melanocytic nevus syndrome, congenital	Enrichment	BRAF, HRAS, NRAS, RAF1	5.05
20	Adult hepatocellular carcinoma	Enrichment	AXIN1, CASP8, CTNNB1, PIK3CA	4.80
21	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS, KRAS, NRAS	4.55
22	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	AKT3, PIK3CA, PIK3R2	4.55
23	Tubulinopathy	Enrichment	TUBA1A, TUBB2A, TUBB2B	4.55
24	Craniopharyngioma	Enrichment	APC, BRAF, CTNNB1	4.55
25	Lissencephaly	Enrichment	TUBA1A, TUBA3E, TUBB, TUBB2B, TUBB3	4.39
26	Colorectal cancer	Enrichment	AKT1, APC, AXIN2, BRAF, CTNNB1, FZD3, NRAS, PIK3CA, PIK3R1	4.35
27	Hepatocellular carcinoma	Enrichment	APC, AXIN1, CASP8, CTNNB1, PIK3CA	4.28
28	Robinow syndrome, autosomal dominant 2	Enrichment	DVL1, DVL3, FZD2	4.16
29	Hemimegalencephaly	Enrichment	AKT3, MTOR, PIK3CA	4.16
30	Congenital fibrosis of the extraocular muscles	Enrichment	TUBA1A, TUBB2B, TUBB3	3.86
31	Thyroid cancer, nonmedullary, 2	Enrichment	BRAF, HRAS, NRAS	3.63
32	Capillary malformation-arteriovenous malformation 1	Enrichment	KRAS, MAP2K1, PIK3CA	3.63
33	Noonan syndrome 3	Enrichment	HRAS, KRAS, RAF1	3.63
34	Pilomyxoid astrocytoma	Enrichment	BRAF, KRAS, RAF1	3.63
35	Follicular thyroid carcinoma	Enrichment	BRAF, HRAS, NRAS	3.63
36	Early-onset autosomal dominant alzheimer disease	Enrichment	APP, PSEN1, PSEN2	3.63
37	Alzheimer disease, familial, 1	Enrichment	APOE, APP, MAPT, PSEN1	3.58
38	Lung cancer	Enrichment	BRAF, CASP8, FAS, KRAS, PIK3CA	3.47
39	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	3.43
40	Alzheimer disease 3	Enrichment	APOE, PSEN1	3.43
41	Pick disease of brain	Enrichment	MAPT, PSEN1	3.43
42	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS, NRAS	3.43
43	Robinow syndrome, autosomal dominant 3	Enrichment	DVL3, FZD2	3.43
44	Arteriovenous malformation	Enrichment	HRAS, MAP2K1, PIK3CA	3.26
45	Breast cancer	Enrichment	AKT1, APC, CASP8, KLC1, KRAS, PIK3CA, RB1CC1	3.22
46	Tooth agenesis	Enrichment	AXIN2, LRP6, WNT10A, WNT10B	3.12
47	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS, MAP2K1, PIK3CA	3.11
48	Desmoid disease, hereditary	Enrichment	APC, CTNNB1	2.96
49	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA, PIK3R1	2.96
50	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3CD, PIK3R1	2.96
51	Large congenital melanocytic nevus	Enrichment	HRAS, NRAS	2.96
52	Desmoid tumor	Enrichment	APC, CTNNB1	2.96
53	Immunodeficiency 14	Enrichment	PIK3CD, PIK3R1	2.96
54	Type 2 diabetes mellitus	Enrichment	AKT2, IL6, INSR, IRS1, IRS2	2.91
55	Lip and oral cavity carcinoma	Enrichment	BRAF, HRAS, PIK3CA	2.86
56	Hereditary breast carcinoma	Enrichment	AKT1, APC, KRAS, PIK3CA, RB1CC1	2.82
57	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	AKT3, PIK3R2	2.66
58	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	KRAS, NRAS	2.66
59	Noonan syndrome with multiple lentigines	Enrichment	BRAF, RAF1	2.66
60	Bladder cancer	Enrichment	CTNNB1, HRAS, KRAS, PIK3CA	2.66
61	Differentiated thyroid carcinoma	Enrichment	BRAF, HRAS, KRAS, NRAS	2.66
62	Long qt syndrome 1	Enrichment	CALM1, CALM2, CALM3, ITPR3	2.60
63	Capillary malformations, congenital	Enrichment	GNAQ, PIK3CA	2.45
64	Exudative vitreoretinopathy 1	Enrichment	CTNNB1, LRP5	2.45
65	Dementia	Enrichment	MAPT, PSEN1	2.45
66	Polycystic liver disease	Enrichment	CTNNB1, LRP5, LRP6	2.40
67	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1, LRP5, LRP6	2.40
68	Klippel-trenaunay-weber syndrome	Enrichment	GNAQ, PIK3CA	2.28
69	Melanoma, uveal	Enrichment	GNAQ, PLCB4	2.28
70	Type 1 diabetes mellitus	Enrichment	IL6, INS	2.28
71	Lung squamous cell carcinoma	Enrichment	KRAS, PIK3CA	2.28
72	Arteriovenous malformations of the brain	Enrichment	BRAF, IL6, KRAS	2.26
73	Polymicrogyria, bilateral perisylvian, x-linked	Enrichment	TUBA1A, TUBB2B	2.14
74	Leukemia, chronic myeloid	Enrichment	KRAS, NRAS	2.14
75	Semantic dementia	Enrichment	MAPT, PSEN1	2.14
76	Overgrowth syndrome	Enrichment	MTOR, PIK3R1	2.14
77	Gastric cancer	Enrichment	APC, IL1B, KRAS, PIK3CA	2.03
78	Exudative vitreoretinopathy	Enrichment	CTNNB1, LRP5	2.02
79	Isolated split hand-split foot malformation	Enrichment	SEM1, WNT10B	2.02
80	West syndrome	Enrichment	CSNK1E, GRIN1, GRIN2B, TUBA1A	2.00
81	Bilateral perisylvian polymicrogyria	Enrichment	TUBA1A, TUBB2B	1.91
82	Progressive non-fluent aphasia	Enrichment	MAPT, PSEN1	1.91
83	Cowden syndrome	Enrichment	AKT1, PIK3CA	1.91
84	Behavioral variant of frontotemporal dementia	Enrichment	MAPT, PSEN1	1.91
85	Ovarian cancer	Enrichment	AKT1, APC, AXIN2, CTNNB1, KRAS, PIK3CA	1.87
86	Polymicrogyria	Enrichment	AKT3, PSMC3	1.82
87	Autosomal dominant macrothrombocytopenia	Enrichment	TUBA8, TUBB1	1.82
88	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3CD, PIK3R1	1.82
89	Autosomal dominant non-syndromic intellectual disability	Enrichment	CSNK2B, GRIN1, GRIN2B, PPP3CA	1.81
90	Frontotemporal dementia 1	Enrichment	MAPT, PSEN1	1.74
91	Periodic fever, familial, autosomal dominant	Enrichment	TNFRSF1A	1.71
92	Anhidrosis, isolated, with normal sweat glands	Enrichment	ITPR2	1.71
93	Chiari malformation type i	Enrichment	DKK1	1.71
94	Macrodactyly	Enrichment	PIK3CA	1.71
95	Proteus syndrome	Enrichment	AKT1	1.71
96	Pyloric stenosis, infantile hypertrophic, 1	Enrichment	NOS1	1.71
97	Skin creases, congenital symmetric circumferential, 1	Enrichment	TUBB	1.71
98	Endosteal hyperostosis, autosomal dominant	Enrichment	LRP5	1.71
99	Nail disorder, nonsyndromic congenital, 1	Enrichment	FZD6	1.71
100	Parkinson disease 1, autosomal dominant	Enrichment	SNCA	1.71
101	Mullerian aplasia and hyperandrogenism	Enrichment	WNT4	1.71
102	Thyrotoxic periodic paralysis 1	Enrichment	CACNA1S	1.71
103	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	1.71
104	Atrophoderma vermiculata	Enrichment	LRP1	1.71
105	Donohue syndrome	Enrichment	INSR	1.71
106	Epilepsy, focal, with speech disorder and with or without impaired intellectual development	Enrichment	GRIN2A	1.71
107	Hypothyroidism, congenital, nongoitrous, 9	Enrichment	IRS4	1.71
108	Sea-blue histiocyte disease	Enrichment	APOE	1.71
109	Hsd10 mitochondrial disease	Enrichment	HSD17B10	1.71
110	Oculoectodermal syndrome	Enrichment	KRAS	1.71
111	Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement	Enrichment	TUBB3	1.71
112	Pallister-killian syndrome	Enrichment	ARAF	1.71
113	Bone mineral density quantitative trait locus 1	Enrichment	LRP5	1.71
114	Exudative vitreoretinopathy 4	Enrichment	LRP5	1.71
115	Spastic paraplegia 10, autosomal dominant	Enrichment	KIF5A	1.71
116	Hyperinsulinemic hypoglycemia, familial, 5	Enrichment	INSR	1.71
117	Immunodeficiency 34	Enrichment	CYBB	1.71
118	Oligodontia-colorectal cancer syndrome	Enrichment	AXIN2	1.71
119	Noonan syndrome 5	Enrichment	RAF1	1.71
120	Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities	Enrichment	INSR	1.71
121	Diabetes mellitus, insulin-resistant, with acanthosis nigricans	Enrichment	INSR	1.71
122	Caspase 8 deficiency	Enrichment	CASP8	1.71
123	46,xx sex reversal with dysgenesis of kidneys, adrenals, and lungs	Enrichment	WNT4	1.71
124	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 2	Enrichment	SLC25A4	1.71
125	Melorheostosis, isolated	Enrichment	MAP2K1	1.71
126	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	1.71
127	Omodysplasia 2	Enrichment	FZD2	1.71
128	Noonan syndrome 7	Enrichment	BRAF	1.71
129	Leopard syndrome 3	Enrichment	BRAF	1.71
130	Acne inversa, familial, 1	Enrichment	NCSTN	1.71
131	Lipoprotein glomerulopathy	Enrichment	APOE	1.71
132	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	1.71
133	Cowden syndrome 5	Enrichment	PIK3CA	1.71
134	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	1.71
135	Keratosis pilaris atrophicans	Enrichment	LRP1	1.71
136	Split-hand/foot malformation 6	Enrichment	WNT10B	1.71
137	Melanosis, neurocutaneous	Enrichment	NRAS	1.71
138	Tooth agenesis, selective, 7	Enrichment	LRP6	1.71
139	Parkinson disease 4, autosomal dominant	Enrichment	SNCA	1.71
140	Cortical dysplasia, complex, with other brain malformations 6	Enrichment	TUBB	1.71
141	Spinocerebellar ataxia 43	Enrichment	MME	1.71
142	Macrothrombocytopenia, isolated, 1, autosomal dominant	Enrichment	TUBB1	1.71
143	Caudal duplication anomaly	Enrichment	AXIN1	1.71
144	Noonan syndrome 6	Enrichment	NRAS	1.71
145	Tooth agenesis, selective, 8	Enrichment	WNT10B	1.71
146	Fetal encasement syndrome	Enrichment	CHUK	1.71
147	Developmental and epileptic encephalopathy 27	Enrichment	GRIN2B	1.71
148	Lissencephaly 7 with cerebellar hypoplasia	Enrichment	CDK5	1.71
149	Sturge-weber syndrome	Enrichment	GNAQ	1.71
150	Intellectual developmental disorder with short stature and variable skeletal anomalies	Enrichment	WIPI2	1.71
151	Exudative vitreoretinopathy 8	Enrichment	LRP6	1.71
152	Mitochondrial dna depletion syndrome 12b , autosomal recessive	Enrichment	SLC25A4	1.71
153	Cerebral cavernous malformations 4	Enrichment	PIK3CA	1.71
154	Immunodeficiency 15b	Enrichment	IKBKB	1.71
155	Pyle disease	Enrichment	SFRP4	1.71
156	Noonan syndrome 13	Enrichment	MAPK1	1.71
157	Spondylometaphyseal dysplasia with corneal dystrophy	Enrichment	PLCB3	1.71
158	Neurodevelopmental disorder with microcephaly, hypotonia, and absent language	Enrichment	PSMB1	1.71
159	Leber congenital amaurosis with early-onset deafness	Enrichment	TUBB4B	1.71
160	Congenital myopathy 20	Enrichment	RYR3	1.71
161	Immunodeficiency 15a	Enrichment	IKBKB	1.71
162	Charcot-marie-tooth disease, demyelinating, type 1j	Enrichment	ITPR3	1.71
163	Congenital myopathy 18	Enrichment	CACNA1S	1.71
164	Developmental and epileptic encephalopathy 91	Enrichment	PPP3CA	1.71
165	Cortical dysplasia, complex, with other brain malformations 10	Enrichment	APC2	1.71
166	Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual development	Enrichment	PPP3CA	1.71
167	Leukoencephalopathy, developmental delay, and episodic neurologic regression syndrome	Enrichment	EIF2AK2	1.71
168	Short syndrome	Enrichment	PIK3R1	1.71
169	Stankiewicz-isidor syndrome	Enrichment	PSMD12	1.71
170	Diarrhea 9	Enrichment	WNT2B	1.71
171	Parkinson-dementia syndrome	Enrichment	MAPT	1.71
172	Auriculocondylar syndrome 2a	Enrichment	PLCB4	1.71
173	Cone-rod dystrophy, x-linked, 3	Enrichment	CACNA1F	1.71
174	Oocyte/zygote/embryo maturation arrest 24	Enrichment	TUBA1C	1.71
175	Supranuclear palsy, progressive, 1	Enrichment	MAPT	1.71
176	Intellectual developmental disorder, autosomal recessive 74	Enrichment	APC2	1.71
177	Cardiomyopathy, dilated, 1v	Enrichment	PSEN2	1.71
178	Mitochondrial dna depletion syndrome 12a , autosomal dominant	Enrichment	SLC25A4	1.71
179	Osteoporosis-pseudoglioma syndrome	Enrichment	LRP5	1.71
180	Myoclonus, intractable, neonatal	Enrichment	KIF5A	1.71
181	Syndromic x-linked intellectual disability type 10	Enrichment	HSD17B10	1.71
182	Coronary artery disease, autosomal dominant 2	Enrichment	LRP6	1.71
183	Bone mineral density quantitative trait locus 16	Enrichment	WNT1	1.71
184	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	1.71
185	Primary aldosteronism, seizures, and neurologic abnormalities	Enrichment	CACNA1D	1.71
186	Deafness, cataract, impaired intellectual development, and polyneuropathy	Enrichment	PSMC3	1.71
187	Alzheimer disease 18	Enrichment	ADAM10	1.71
188	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Enrichment	AKT3	1.71
189	Lymphangioma	Enrichment	BRAF	1.71
190	Thrombocytopenia 4	Enrichment	CYCS	1.71
191	Progressive supranuclear palsy	Enrichment	MAPT	1.71
192	Hemifacial myohyperplasia	Enrichment	PIK3CA	1.71
193	Major affective disorder 7	Enrichment	XBP1	1.71
194	Malignant hyperthermia 5	Enrichment	CACNA1S	1.71
195	Neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal recessive	Enrichment	GRIN1	1.71
196	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	1.71
197	Polycystic liver disease 4 with or without kidney cysts	Enrichment	LRP5	1.71
198	Phace association	Enrichment	BRAF	1.71
199	Amyotrophic lateral sclerosis 25	Enrichment	KIF5A	1.71
200	Cerebral amyloid angiopathy, app-related	Enrichment	APP	1.71
201	Santos syndrome	Enrichment	WNT7A	1.71
202	Melorheostosis	Enrichment	MAP2K1	1.71
203	Cortical dysplasia, complex, with other brain malformations 7	Enrichment	TUBB2B	1.71
204	Cardiomyopathy, dilated, 1u	Enrichment	PSEN1	1.71
205	Leopard syndrome 2	Enrichment	RAF1	1.71
206	Intellectual developmental disorder, autosomal dominant 6, with or without seizures	Enrichment	GRIN2B	1.71
207	Sinoatrial node dysfunction and deafness	Enrichment	CACNA1D	1.71
208	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	1.71
209	Multiple sclerosis 5	Enrichment	TNFRSF1A	1.71
210	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	1.71
211	Immunodeficiency 90 with encephalopathy, functional hyposplenia, and hepatic dysfunction	Enrichment	FADD	1.71
212	Long qt syndrome 16	Enrichment	CALM3	1.71
213	Cowden syndrome 6	Enrichment	AKT1	1.71
214	Oocyte/zygote/embryo maturation arrest 23	Enrichment	TUBA4A	1.71
215	Cortical dysplasia, complex, with other brain malformations 2	Enrichment	KIF5C	1.71
216	Reticulate acropigmentation of kitamura	Enrichment	ADAM10	1.71
217	Frontotemporal dementia and/or amyotrophic lateral sclerosis 9	Enrichment	TUBA4A	1.71
218	Immunodeficiency 14b, autosomal recessive	Enrichment	PIK3CD	1.71
219	Achromatopsia 7	Enrichment	ATF6	1.71
220	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	1.71
221	Microphthalmia/coloboma 11	Enrichment	FZD5	1.71
222	Acne inversa, familial, 2, with or without dowling-degos disease	Enrichment	PSENEN	1.71
223	Developmental and epileptic encephalopathy 101	Enrichment	GRIN1	1.71
224	Mitochondrial metabolism disease	Enrichment	SLC25A4	1.71
225	Acne inversa, familial, 3	Enrichment	PSEN1	1.71
226	Neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal dominant	Enrichment	GRIN1	1.71
227	Tnf receptor-associated periodic fever syndrome	Enrichment	TNFRSF1A	1.71
228	Facial palsy, congenital, with ptosis and velopharyngeal dysfunction	Enrichment	TUBB6	1.71
229	Okur-chung neurodevelopmental syndrome	Enrichment	CSNK2A1	1.71
230	Bartsocas-papas syndrome 2	Enrichment	CHUK	1.71
231	Dystonia 33	Enrichment	EIF2AK2	1.71
232	Classic progressive supranuclear palsy syndrome	Enrichment	MAPT	1.71
233	Trigonitis	Enrichment	RAF1	1.71
234	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	1.71
235	Auriculocondylar syndrome 2b	Enrichment	PLCB4	1.71
236	Sotos syndrome 3	Enrichment	APC2	1.71
237	Craniometadiaphyseal osteosclerosis with hip dysplasia	Enrichment	AXIN1	1.71
238	Congenital membranous nephropathy due to maternal anti-neutral endopeptidase alloimmunization	Enrichment	MME	1.71
239	Macrothrombocytopenia, isolated, 2, autosomal dominant	Enrichment	TUBA8	1.71
240	Adenoid ameloblastoma	Enrichment	CTNNB1	1.71
241	Long qt syndrome 15	Enrichment	CALM2	1.71
242	Lissencephaly due to tuba1a mutation	Enrichment	TUBA1A	1.71
243	Neurodevelopmental disorder with dysmorphic facies and ischiopubic hypoplasia	Enrichment	NAE1	1.71
244	Congenital myopathy 26	Enrichment	TUBA4A	1.71
245	Spastic ataxia 11, autosomal dominant	Enrichment	TUBA4A	1.71
246	Atypical progressive supranuclear palsy syndrome	Enrichment	MAPT	1.71
247	Amyotrophic lateral sclerosis type 22	Enrichment	TUBA4A	1.71
248	Hypospadias	Enrichment	PIK3CA	1.71
249	Craniodigital syndrome and intellectual disability syndrome	Enrichment	CSNK2B	1.71
250	Lrp5-related primary osteoporosis	Enrichment	LRP5	1.71
251	Capillary hemangioma	Enrichment	AKT3	1.71
252	Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy	Enrichment	ITPR3	1.71
253	Charcot-marie-tooth disease type 2t	Enrichment	MME	1.71
254	Neurodegeneration, early-childhood-onset, with retinitis pigmentosa, sensorineural hearing loss, and demyelinating peripheral neuropathy	Enrichment	KLC4	1.71
255	Mme-related autosomal dominant charcot marie tooth disease type 2	Enrichment	MME	1.71
256	Rhabdomyolysis 2	Enrichment	ATP2A2	1.71
257	Grin2b-related neurodevelopmental disorder	Enrichment	GRIN2B	1.71
258	Landau-kleffner syndrome	Enrichment	GRIN2A	1.71
259	Congenital pulmonary airway malformation	Enrichment	KRAS	1.71
260	Polymicrogyria with optic nerve hypoplasia	Enrichment	TUBA8	1.71
261	Rare venous malformation	Enrichment	PIK3CA	1.71
262	Familial adenomatous polyposis	Enrichment	APC	1.71
263	Diaphragmatic eventration	Enrichment	PIK3CA	1.71
264	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	1.71
265	Syringocystadenoma papilliferum	Enrichment	BRAF	1.71
266	Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to ikbka deficiency	Enrichment	CHUK	1.71
267	Aldosterone-producing adenoma with seizures and neurological abnormalities	Enrichment	CACNA1D	1.71
268	Rare combined vascular malformation	Enrichment	PIK3CA	1.71
269	Ganglioglioma	Enrichment	BRAF	1.71
270	Cavernous lymphangioma	Enrichment	PIK3CA	1.71
271	Intellectual disability, autosomal dominant 8	Enrichment	GRIN1	1.71
272	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	1.71
273	Nongerminomatous germ cell tumor	Enrichment	BRAF	1.71
274	Early-onset epileptic encephalopathy and intellectual disability due to grin2a mutation	Enrichment	GRIN2A	1.71
275	Grin2a-related disorders	Enrichment	GRIN2A	1.71
276	Phace syndrome	Enrichment	BRAF	1.71
277	Gardner syndrome	Enrichment	APC	1.71
278	Osteosclerosis-developmental delay-craniosynostosis syndrome	Enrichment	LRP5	1.71
279	5q22 microdeletion syndrome	Enrichment	APC	1.71
280	Phakomatosis pigmentokeratotica	Enrichment	HRAS	1.71
281	Pash syndrome	Enrichment	NCSTN	1.71
282	Periodic paralysis with transient compartment-like syndrome	Enrichment	CACNA1S	1.71
283	Attenuated familial adenomatous polyposis	Enrichment	APC	1.71
284	Huntington's disease-like	Enrichment	PSEN2	1.71
285	Autosomal dominant charcot-marie-tooth disease type 2 due to kif5a mutation	Enrichment	KIF5A	1.71
286	Classic hairy cell leukemia	Enrichment	BRAF	1.71
287	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	1.71
288	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	1.71
289	Macrodactyly of toe	Enrichment	PIK3CA	1.71
290	Neurocutaneous melanocytosis	Enrichment	NRAS	1.71
291	Microcystic stromal tumor	Enrichment	CTNNB1	1.71
292	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	1.71
293	Long qt syndrome	Enrichment	CACNA1S, CALM1, CALM2	1.67
294	Non-immune hydrops fetalis	Enrichment	FZD6, HRAS, KRAS	1.67
295	Juvenile myelomonocytic leukemia	Enrichment	KRAS, NRAS	1.67
296	Meningioma	Enrichment	AKT1, PIK3CA	1.67
297	Multiple sclerosis	Enrichment	ITPR1, TNFRSF1A	1.54
298	Osteoporosis	Enrichment	LRP5, WNT1	1.54
299	Medulloblastoma	Enrichment	APC, CTNNB1	1.54
300	Lung cancer susceptibility 3	Enrichment	BRAF, KRAS	1.54
301	Myopia	Enrichment	CACNA1F, SLC25A4	1.48
302	Lynch syndrome	Enrichment	KRAS, PIK3CA	1.48
303	Spinocerebellar ataxia 29	Enrichment	ITPR1	1.42
304	Cerebral amyloid angiopathy, cst3-related	Enrichment	APP	1.42
305	Dystonia 4, torsion, autosomal dominant	Enrichment	TUBB4A	1.42
306	Acrokeratosis verruciformis	Enrichment	ATP2A2	1.42
307	Tooth agenesis, selective, 4	Enrichment	WNT10A	1.42
308	Costello syndrome	Enrichment	HRAS	1.42
309	Hyperlipoproteinemia, type i	Enrichment	LPL	1.42
310	Van buchem disease	Enrichment	LRP5	1.42
311	Epiphyseal dysplasia, multiple, with early-onset diabetes mellitus	Enrichment	EIF2AK3	1.42
312	Schopf-schulz-passarge syndrome	Enrichment	WNT10A	1.42
313	Ulna and fibula, absence of, with severe limb deficiency	Enrichment	WNT7A	1.42
314	Bladder exstrophy and epispadias complex	Enrichment	WNT3	1.42
315	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	1.42
316	Brody disease	Enrichment	ATP2A1	1.42
317	Night blindness, congenital stationary, type 2a	Enrichment	CACNA1F	1.42
318	Odontoonychodermal dysplasia	Enrichment	WNT10A	1.42
319	Pulmonic stenosis	Enrichment	BRAF	1.42
320	Tetraamelia syndrome 1	Enrichment	WNT3	1.42
321	Spastic paraplegia, optic atrophy, and neuropathy	Enrichment	KLC2	1.42
322	Hyperinsulinemic hypoglycemia, familial, 4	Enrichment	INSR	1.42
323	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	1.42
324	Keratosis, seborrheic	Enrichment	PIK3CA	1.42
325	Osteogenesis imperfecta, type xv	Enrichment	WNT1	1.42
326	Melanoma, cutaneous malignant 6	Enrichment	KLC1	1.42
327	Encephalocraniocutaneous lipomatosis	Enrichment	KRAS	1.42
328	Roifman-chitayat syndrome	Enrichment	PIK3CD	1.42
329	Lipase deficiency, combined	Enrichment	LPL	1.42
330	Maturity-onset diabetes of the young, type 10	Enrichment	INS	1.42
331	Muscular dystrophy, limb-girdle, autosomal recessive 3	Enrichment	TUBA1A	1.42
332	Noonan syndrome 8	Enrichment	PIK3CA	1.42
333	Fibular aplasia or hypoplasia, femoral bowing, and poly-, syn-, and oligodactyly	Enrichment	WNT7A	1.42
334	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	1.42
335	Spastic paraplegia 76, autosomal recessive	Enrichment	CAPN1	1.42
336	Albinism, oculocutaneous, type ia	Enrichment	NOX4	1.42
337	Long qt syndrome 14	Enrichment	CALM1	1.42
338	Hyperproinsulinemia	Enrichment	INS	1.42
339	Developmental dysplasia of the hip 3	Enrichment	LRP1	1.42
340	Birk-aharoni syndrome	Enrichment	PSMC1	1.42
341	Microcephaly 21, primary, autosomal recessive	Enrichment	GAPDH	1.42
342	Poirier-bienvenu neurodevelopmental syndrome	Enrichment	CSNK2B	1.42
343	Autoinflammatory disease, familial, behcet-like 3	Enrichment	RELA	1.42
344	Cebalid syndrome	Enrichment	MTOR	1.42
345	Keratoconus 9	Enrichment	TUBA3D	1.42
346	Hyperlipoproteinemia, type iii	Enrichment	APOE	1.42
347	Proteasome-associated autoinflammatory syndrome 3	Enrichment	PSMB4	1.42
348	Autosomal recessive limb-girdle muscular dystrophy type 2d	Enrichment	TUBA1A	1.42
349	Parkinson disease 15, autosomal recessive early-onset	Enrichment	SNCA	1.42
350	Immunodeficiency 127	Enrichment	TNF	1.42
351	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	1.42
352	Rela fusion-positive ependymoma	Enrichment	RELA	1.42
353	Bilateral generalized polymicrogyria	Enrichment	GRIN1	1.42
354	Lissencephaly 3	Enrichment	TUBA1A	1.42
355	Intellectual developmental disorder, autosomal dominant 21	Enrichment	GRIN2A	1.42
356	Senior-loken syndrome 7	Enrichment	AKT3	1.42
357	Developmental and epileptic encephalopathy 46	Enrichment	GRIN2D	1.42
358	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	1.42
359	Frontotemporal dementia and/or amyotrophic lateral sclerosis 4	Enrichment	KIF5A	1.42
360	Chromosome 15q13.3 deletion syndrome	Enrichment	CHRNA7	1.42
361	Ocular melanoma	Enrichment	PLCB4	1.42
362	Diabetes mellitus, permanent neonatal, 4	Enrichment	INS	1.42
363	Inflammatory skin and bowel disease, neonatal, 1	Enrichment	ADAM17	1.42
364	Cortical dysplasia, complex, with other brain malformations 1	Enrichment	TUBB3	1.42
365	Periampullary adenoma	Enrichment	APC	1.42
366	Familial lipoprotein lipase deficiency	Enrichment	LPL	1.42
367	Gastric adenocarcinoma and proximal polyposis of the stomach	Enrichment	APC	1.42
368	Immune system disease	Enrichment	PIK3CD	1.42
369	Bardet-biedl syndrome 16	Enrichment	AKT3	1.42
370	Congenital disorder of glycosylation, type iw, autosomal dominant	Enrichment	CACNA1D	1.42
371	Smith-kingsmore syndrome	Enrichment	MTOR	1.42
372	17q24.2 microdeletion syndrome	Enrichment	PSMD12	1.42
373	Charcot-marie-tooth disease, axonal, type 2t	Enrichment	MME	1.42
374	Torsion dystonia 4	Enrichment	TUBB4A	1.42
375	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.42
376	Multiple benign circumferential skin creases on limbs	Enrichment	TUBB	1.42
377	Intermittent hydrarthrosis	Enrichment	TNFRSF1A	1.42
378	Demyelinating polyneuropathy	Enrichment	KIF5A	1.42
379	Rolandic epilepsy-speech dyspraxia syndrome	Enrichment	GRIN2A	1.42
380	Teratoma	Enrichment	CTNNB1	1.42
381	Osteosclerosis	Enrichment	LRP5	1.42
382	Bladder exstrophy-epispadias-cloacal exstrophy complex	Enrichment	WNT3	1.42
383	Common variable immunodeficiency 12	Enrichment	NFKB1	1.42
384	Skeletal muscle disease	Enrichment	KIF5B	1.42
385	Tafro syndrome	Enrichment	MAP2K2	1.42
386	Continuous spikes and waves during sleep	Enrichment	TUBA1A	1.42
387	Oculootodental syndrome	Enrichment	FADD	1.42
388	Epilepsy-aphasia spectrum	Enrichment	GRIN2A	1.42
389	Phakomatosis cesioflammea	Enrichment	GNAQ	1.42
390	Wooly hair nevus	Enrichment	HRAS	1.42
391	Cerebral palsy	Enrichment	GRIN2B, TUBA1A, TUBB4A	1.41
392	Dandy-walker syndrome	Enrichment	BRAF, TUBA1A	1.38
393	Behcet syndrome	Enrichment	FAS, TNFRSF1A	1.29
394	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	KIF5A, MME	1.29
395	Darier-white disease	Enrichment	ATP2A2	1.25
396	Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss	Enrichment	TUBB1	1.25
397	Type 1 diabetes mellitus 2	Enrichment	INS	1.25
398	Prognathism, mandibular	Enrichment	CSNK2B	1.25
399	Ataxia-telangiectasia	Enrichment	BRAF	1.25
400	Proteasome-associated autoinflammatory syndrome 1	Enrichment	PSMB4	1.25
401	Gillespie syndrome	Enrichment	ITPR1	1.25
402	Sengers syndrome	Enrichment	SLC25A4	1.25
403	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.25
404	Niemann-pick disease, type a	Enrichment	APBB1	1.25
405	Mullerian duct aplasia, unilateral renal agenesis, and cervicothoracic somite anomalies	Enrichment	WNT4	1.25
406	Microphthalmia, syndromic 9	Enrichment	WNT7B	1.25
407	Menkes disease	Enrichment	EIF2AK3	1.25
408	Tooth agenesis, selective, 2	Enrichment	WNT10A	1.25
409	Osteopetrosis, autosomal dominant 1	Enrichment	LRP5	1.25
410	Psoriatic arthritis	Enrichment	TNF	1.25
411	Niemann-pick disease, type b	Enrichment	APBB1	1.25
412	Leukodystrophy, hypomyelinating, 6	Enrichment	TUBB4A	1.25
413	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.25
414	Cenani-lenz syndactyly syndrome	Enrichment	APC	1.25
415	Oocyte/zygote/embryo maturation arrest 2	Enrichment	TUBB8	1.25
416	Anus, imperforate	Enrichment	CTNNB1	1.25
417	Cortical dysplasia, complex, with other brain malformations 5	Enrichment	TUBB2A	1.25
418	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.25
419	Auditory neuropathy and optic atrophy	Enrichment	GRIN2C	1.25
420	Keratosis follicularis spinulosa decalvans	Enrichment	LRP1	1.25
421	Tethered spinal cord syndrome	Enrichment	BRAF	1.25
422	Torsion dystonia 1	Enrichment	EIF2AK2	1.25
423	Proteosome-associated autoinflammatory syndrome	Enrichment	PSMB4	1.25
424	Nail disease	Enrichment	FZD6	1.25
425	Myxoid liposarcoma	Enrichment	DDIT3	1.25
426	Migraine without aura	Enrichment	TNF	1.25
427	Spermatocytoma	Enrichment	HRAS	1.25
428	Tetraamelia syndrome	Enrichment	WNT3	1.25
429	Colon adenocarcinoma	Enrichment	APC	1.25
430	Neonatal inflammatory skin and bowel disease	Enrichment	ADAM17	1.25
431	Anastomosing haemangioma	Enrichment	GNAQ	1.25
432	Thyrotoxic periodic paralysis	Enrichment	CACNA1S	1.25
433	Thyroid hemiagenesis	Enrichment	PSMD3	1.25
434	Keratoacanthoma	Enrichment	PIK3CA	1.25
435	Vogt-koyanagi-harada disease	Enrichment	FAS	1.25
436	Apc-associated polyposis conditions	Enrichment	APC	1.25
437	Hepatoblastoma	Enrichment	APC, CTNNB1	1.21
438	Brittle bone disorder	Enrichment	LRP5, WNT1	1.14
439	Malaria	Enrichment	NOS2, TNF	1.14
440	Kaposi sarcoma	Enrichment	IL6	1.12
441	Dowling-degos disease 1	Enrichment	ADAM10	1.12
442	Diffuse gastric and lobular breast cancer syndrome	Enrichment	KRAS	1.12
443	Acyl-coa dehydrogenase, very long-chain, deficiency of	Enrichment	DVL2	1.12
444	Ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	WNT10A	1.12
445	Granulomatous disease, chronic, x-linked	Enrichment	CYBB	1.12
446	Thyroid cancer, nonmedullary, 1	Enrichment	BRAF	1.12
447	Astigmatism	Enrichment	GRIN2B	1.12
448	Macular degeneration, age-related, 1	Enrichment	APOE	1.12
449	Autoimmune lymphoproliferative syndrome	Enrichment	FAS	1.12
450	Amyotrophy, monomelic	Enrichment	RYR3	1.12
451	Aland island eye disease	Enrichment	CACNA1F	1.12
452	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	1.12
453	Auriculocondylar syndrome 1	Enrichment	PLCB4	1.12
454	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	1.12
455	Focal cortical dysplasia, type ii	Enrichment	MTOR	1.12
456	Pilomatrixoma	Enrichment	CTNNB1	1.12
457	Spinocerebellar ataxia 15	Enrichment	ITPR1	1.12
458	Alazami syndrome	Enrichment	CTNNB1	1.12
459	Enophthalmos	Enrichment	CSNK2B	1.12
460	Syndactyly	Enrichment	CSNK2B	1.12
461	Neonatal diabetes mellitus	Enrichment	INS	1.12
462	Dowling-degos disease	Enrichment	PSENEN	1.12
463	Lung sarcomatoid carcinoma	Enrichment	KRAS	1.12
464	Orofacial cleft	Enrichment	LRP6	1.12
465	Ectodermal dysplasia	Enrichment	WNT10A	1.12
466	Retinopathy of prematurity	Enrichment	LRP5	1.12
467	Cerebrovascular disease	Enrichment	PIK3CA	1.12
468	Pilocytic astrocytoma	Enrichment	KRAS	1.12
469	Newborn respiratory distress syndrome	Enrichment	BRAF	1.12
470	Epidermolytic nevus	Enrichment	HRAS	1.12
471	Idiopathic achalasia	Enrichment	NOS1	1.12
472	Malignant hyperthermia	Enrichment	CACNA1S	1.12
473	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.12
474	Eyelid coloboma	Enrichment	FZD5	1.12
475	Coronary artery anomaly	Enrichment	LPL	1.12
476	Cerebral malaria	Enrichment	TNF	1.12
477	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	1.12
478	Isolated focal cortical dysplasia type ii	Enrichment	MTOR	1.12
479	Vitreoretinopathy	Enrichment	LRP5	1.12
480	Orofacial clefting syndrome	Enrichment	LRP6	1.12
481	Lens coloboma	Enrichment	FZD5	1.12
482	Parkinson disease, late-onset	Enrichment	MAPT, SNCA	1.11
483	Familial isolated dilated cardiomyopathy	Enrichment	PSEN1, PSEN2, RAF1	1.08
484	Developmental and epileptic encephalopathy 1	Enrichment	CSNK1E, GRIN1	1.08
485	Hydrops fetalis, nonimmune	Enrichment	FZD6, HRAS	1.05
486	Auditory neuropathy	Enrichment	KIF5A, TUBB4A	1.05
487	Microcephaly	Enrichment	CTNNB1, GRIN2B, MAPK1, PSMC3, TUBB4A	1.05
488	Alzheimer disease 2	Enrichment	APOE	1.03
489	Sotos syndrome	Enrichment	APC2	1.03
490	Hyperlipidemia, familial combined, 3	Enrichment	LPL	1.03
491	Dementia, lewy body	Enrichment	SNCA	1.03
492	Niemann-pick disease, type c1	Enrichment	APBB1	1.03
493	Kearns-sayre syndrome	Enrichment	KIF5B	1.03
494	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	1.03
495	Familial adenomatous polyposis 1	Enrichment	APC	1.03
496	Amblyopia	Enrichment	CACNA1F	1.03
497	Niemann-pick disease	Enrichment	APBB1	1.03
498	2q23.1 microduplication syndrome	Enrichment	KIF5C	1.03
499	Vascular dementia	Enrichment	TNF	1.03
500	Autosomal recessive hypohidrotic ectodermal dysplasia syndrome	Enrichment	WNT10A	1.03
501	Autosomal thrombocytopenia with normal platelets	Enrichment	CYCS	1.03
502	Female infertility due to oocyte meiotic arrest	Enrichment	TUBB8	1.03
503	Coloboma of choroid and retina	Enrichment	FZD5	1.03
504	Sleep disorder	Enrichment	GRIN2B	1.03
505	Myeloma, multiple	Enrichment	BRAF, KRAS, PIK3R2	1.03
506	Developmental dysplasia of the hip 1	Enrichment	PSMC3	0.96
507	Coloboma of optic nerve	Enrichment	FZD5	0.96
508	Hypokalemic periodic paralysis, type 1	Enrichment	CACNA1S	0.96
509	Cowden syndrome 1	Enrichment	PIK3CA	0.96
510	Weyers acrofacial dysostosis	Enrichment	CTNNB1	0.96
511	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 1	Enrichment	SLC25A4	0.96
512	Telangiectasia, hereditary hemorrhagic, type 1	Enrichment	PSEN1	0.96
513	Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 1	Enrichment	TUBB2B	0.96
514	Hemihyperplasia, isolated	Enrichment	PIK3CA	0.96
515	Wilms tumor 5	Enrichment	BRAF	0.96
516	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	0.96
517	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1	0.96
518	Diarrhea	Enrichment	WNT2B	0.96
519	Lipid metabolism disorder	Enrichment	APOE	0.96
520	Patent ductus arteriosus	Enrichment	PSMC3	0.96
521	Adrenocortical carcinoma	Enrichment	CTNNB1	0.96
522	Early myoclonic encephalopathy	Enrichment	TUBA1A	0.96
523	46,xy disorder of sex development	Enrichment	INSR	0.96
524	Multicystic kidney dysplasia	Enrichment	FZD3	0.96
525	Multicystic dysplastic kidney	Enrichment	FZD3	0.96
526	Peripheral nervous system disease	Enrichment	KIF5A, MME	0.90
527	Neuropathy	Enrichment	KIF5A, MME	0.90
528	Renal cell carcinoma, papillary, 1	Enrichment	MTOR	0.89
529	Alzheimer's disease 1	Enrichment	APP	0.89
530	Megacolon	Enrichment	AKT3	0.89
531	Common variable immunodeficiency	Enrichment	NFKB1	0.89
532	Lymphoma, non-hodgkin, familial	Enrichment	BRAF	0.84
533	Lennox-gastaut syndrome	Enrichment	MAPK10	0.84
534	Cryptorchidism	Enrichment	TUBA1A	0.84
535	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	0.84
536	Permanent neonatal diabetes mellitus	Enrichment	INS	0.84
537	Congenital nervous system abnormality	Enrichment	CTNNB1, PSEN1, TUBA1A, TUBB4A	0.83
538	Nervous system disease	Enrichment	CTNNB1, PSEN1, TUBA1A, TUBB4A	0.83
539	Autism spectrum disorder	Enrichment	CSNK2A1, CSNK2B, GRIN2B, MAP2K1	0.80
540	Tooth agenesis, selective, 1	Enrichment	AXIN2	0.79
541	Cardiomyopathy, familial hypertrophic, 4	Enrichment	BRAF	0.79
542	Tracheoesophageal fistula with or without esophageal atresia	Enrichment	APC2	0.79
543	Charge syndrome	Enrichment	TNFRSF1A	0.79
544	Cryptorchidism, unilateral or bilateral	Enrichment	TUBA1A	0.79
545	Inflammatory bowel disease 1	Enrichment	IL6	0.79
546	Chronic granulomatous disease	Enrichment	CYBB	0.79
547	Primary hyperaldosteronism	Enrichment	BRAF	0.79
548	Ventricular septal defect	Enrichment	BRAF	0.79
549	Colonic benign neoplasm	Enrichment	APC	0.79
550	Hydrops fetalis	Enrichment	RYR3	0.79
551	Cat eye syndrome	Enrichment	FZD5	0.75
552	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	0.75
553	Melanoma	Enrichment	BRAF	0.75
554	Achromatopsia	Enrichment	ATF6	0.75
555	Isolated tracheo-esophageal fistula	Enrichment	APC2	0.75
556	Leukemia, acute myeloid	Enrichment	KRAS, NRAS	0.74
557	Epilepsy	Enrichment	GRIN2A, GRIN2B	0.74
558	Benign epilepsy with centrotemporal spikes	Enrichment	GRIN1, GRIN2A	0.73
559	Asthma	Enrichment	TNF	0.71
560	Diabetes mellitus	Enrichment	INS	0.71
561	Mitochondrial myopathy	Enrichment	SLC25A4	0.71
562	Specific learning disability	Enrichment	MAPK1	0.71
563	Dilated cardiomyopathy	Enrichment	BRAF, KIF5B, RAF1	0.70
564	Centralopathic epilepsy	Enrichment	GRIN1, GRIN2A	0.70
565	Hypertrophic cardiomyopathy	Enrichment	KIF5B, SLC25A4	0.70
566	Optic atrophy plus syndrome	Enrichment	CACNA1F, TUBB6	0.68
567	Congenital hypothyroidism	Enrichment	TUBB1	0.68
568	Early-onset parkinson's disease	Enrichment	SNCA	0.68
569	Congenital long qt syndrome	Enrichment	ITPR3	0.68
570	Microphthalmia/coloboma 12	Enrichment	FZD5	0.65
571	Osteogenesis imperfecta, type iv	Enrichment	WNT1	0.65
572	Protein-deficiency anemia	Enrichment	NRAS	0.65
573	Nk-cell enteropathy	Enrichment	PIK3CB	0.65
574	Thrombocytopenia	Enrichment	CYCS, TUBB1	0.63
575	Cone-rod dystrophy 6	Enrichment	CACNA1F	0.62
576	Coloboma of macula	Enrichment	FZD5	0.60
577	Renal cell carcinoma, nonpapillary	Enrichment	MTOR	0.60
578	Wilms tumor 1	Enrichment	BRAF	0.60
579	Corpus callosum, agenesis of	Enrichment	TUBA1A	0.60
580	Osteogenesis imperfecta, type iii	Enrichment	WNT1	0.60
581	Hydrocephalus	Enrichment	FZD3	0.60
582	Anterior segment dysgenesis	Enrichment	ITPR1	0.60
583	Familial hypercholesterolemia	Enrichment	APOE	0.60
584	Isolated corpus callosum agenesis	Enrichment	TUBA1A	0.60
585	Rare genetic intellectual disability	Enrichment	MTOR	0.60
586	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	TUBA1A	0.60
587	Hydrocephalus, congenital, 1	Enrichment	TUBB	0.57
588	Rhabdomyosarcoma	Enrichment	HRAS	0.57
589	Isolated congenital microcephaly	Enrichment	TUBA3E	0.57
590	Spastic ataxia	Enrichment	ITPR1, TUBB3	0.56
591	Melanoma, cutaneous malignant 1	Enrichment	BRAF	0.55
592	Sudden infant death syndrome	Enrichment	CALM2	0.55
593	Undetermined early-onset epileptic encephalopathy	Enrichment	GRIN2D, PPP3CA	0.53
594	Heart, malformation of	Enrichment	MAPK1	0.53
595	Patent foramen ovale	Enrichment	PSMC3	0.53
596	Early infantile developmental and epileptic encephalopathy	Enrichment	GRIN1	0.53
597	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	MAPT, PSEN1	0.51
598	Diffuse large b-cell lymphoma	Enrichment	BRAF	0.51
599	Esophageal atresia/tracheoesophageal fistula	Enrichment	APC2	0.51
600	Congenital myopathy	Enrichment	CACNA1S	0.51
601	Macs syndrome	Enrichment	WNT7B	0.49
602	Maturity-onset diabetes of the young	Enrichment	INS	0.49
603	Craniosynostosis	Enrichment	GRIN2B	0.49
604	Cardiomyopathy, dilated, 1a	Enrichment	LPL	0.47
605	Endometrial cancer	Enrichment	PIK3CA	0.47
606	Centronuclear myopathy	Enrichment	CACNA1S	0.47
607	Attention deficit-hyperactivity disorder	Enrichment	KIF5B	0.46
608	Myocardial infarction	Enrichment	PSMA6	0.46
609	Microphthalmia	Enrichment	WNT7B	0.46
610	Skin disease	Enrichment	NCSTN	0.46
611	Congenital stationary night blindness	Enrichment	CACNA1F	0.44
612	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	0.43
613	Autoinflammatory disease	Enrichment	TNFRSF1A	0.43
614	Scoliosis	Enrichment	GRIN2B	0.43
615	Cone-rod dystrophy 2	Enrichment	ATF6, CACNA1F	0.42
616	Pancreatic cancer	Enrichment	KRAS	0.41
617	Complex neurodevelopmental disorder	Enrichment	CSNK2A1, GRIN2B, PSMD12	0.37
618	Hirschsprung disease 1	Enrichment	AXIN2	0.36
619	Prostate cancer	Enrichment	PIK3CA	0.36
620	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.32
621	Severe combined immunodeficiency	Enrichment	IKBKB	0.32
622	Left ventricular noncompaction	Enrichment	RAF1	0.31
623	Eye disease	Enrichment	CACNA1F	0.31
624	Fetal akinesia deformation sequence 1	Enrichment	TUBA1A	0.29
625	Systemic lupus erythematosus	Enrichment	TNF	0.27
626	Distal arthrogryposis	Enrichment	FZD3	0.25
627	Hereditary spastic paraplegia	Enrichment	KIF5A	0.25
628	Hypertelorism	Enrichment	PIK3CA	0.20
629	Hereditary breast ovarian cancer syndrome	Enrichment	KRAS	0.18
630	Autosomal recessive non-syndromic intellectual disability	Enrichment	GRIN1	0.17
631	Primary ovarian insufficiency	Enrichment	RYR3	0.16
632	Inherited cancer-predisposing syndrome	Enrichment	APC, AXIN2	0.14
633	Mitochondrial disease	Enrichment	SLC25A4	0.09
634	Leber plus disease	Enrichment	TUBB4B	0.07
635	Hereditary retinal dystrophy	Enrichment	ATF6, CACNA1F, LRP5	0.04
636	Fundus dystrophy	Enrichment	ATF6, CACNA1F, LRP5	0.04
637	Retinitis pigmentosa	Enrichment	CACNA1F	0.01

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Alzheimer's disease and miRNA effects

Pathway Network for Alzheimer's disease and miRNA effects

Member Pathways for Alzheimer's disease and miRNA effects

Pathways in the Alzheimer's disease and miRNA effects SuperPath

Associated Genes for Alzheimer's disease and miRNA effects

Associated Disorders for Alzheimer's disease and miRNA effects

Disorders associated with Alzheimer's disease and miRNA effects SuperPath

STRING Interaction Network for Alzheimer's disease and miRNA effects

Sources for Alzheimer's disease and miRNA effects