Amino acid metabolism

No Pathway Network information available for Amino acid metabolism

Pathways in the Amino acid metabolism SuperPath

#	Name	Source	Genes
1	Amino acid metabolism	WikiPathways	ACAA1 ACADM ACLY ACO2 ACSS1 ADH1C ADH4 ADH5 ADH7 ALDH18A1 ALDH1A1 ALDH7A1 AOC3 ARG1 ARG2 ASNS ASS1 AUH BCAT1 BHMT CAD CBS CPS1 CS CTH DBH DDC DLD DLST EHHADH EPRS1 FAH FARSB FH FTCD G6PC2 GCLM GLS GLUD1 GLUL GOT1 GOT2 GPT2 GSR GSS HADH HAL HDC HIBADH HIBCH HMGCL HMGCS2 HNMT IARS1 IDH1 LARS2 LDHA MAOA MARS2 MCCC1 MDH1 MDH2 MMUT MPST OAT ODC1 OGDH OTC P4HA2 PC PCK1 PDHA1 PDHX PDK4 PKM PNMT PPM1L PYCR1 RARS1 SDHA SDS SMS SRM SUCLG1 TAT TDO2 TH TPH1 TPO VARS1 WARS1 (see all 91) (see less)
2	Amino acid metabolism pathway excerpt: histidine catabolism extension	WikiPathways	FTCD GLUD1 GPT2 HAL

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	GPT2	Glutamic--Pyruvic Transaminase 2	Protein Coding	2
2	HAL	Histidine Ammonia-Lyase	Protein Coding	2
3	GLUD1	Glutamate Dehydrogenase 1	Protein Coding	2
4	FTCD	Formimidoyltransferase Cyclodeaminase	Protein Coding	2
5	ACSS1	Acyl-CoA Synthetase Short Chain Family Member 1	Protein Coding	1
6	G6PC2	Glucose-6-Phosphatase Catalytic Subunit 2	Protein Coding	1
7	ACAA1	Acetyl-CoA Acyltransferase 1	Protein Coding	1
8	DLST	Dihydrolipoamide S-Succinyltransferase	Protein Coding	1
9	MARS2	Methionyl-TRNA Synthetase 2, Mitochondrial	Protein Coding	1
10	P4HA2	Prolyl 4-Hydroxylase Subunit Alpha 2	Protein Coding	1
11	SUCLG1	Succinate-CoA Ligase GDP/ADP-Forming Subunit Alpha	Protein Coding	1
12	CBS	Cystathionine Beta-Synthase	Protein Coding	1
13	AOC3	Amine Oxidase Copper Containing 3	Protein Coding	1
14	PDHX	Pyruvate Dehydrogenase Complex Component X	Protein Coding	1
15	CAD	Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, And Dihydroorotase	Protein Coding	1
16	WARS1	Tryptophanyl-TRNA Synthetase 1	Protein Coding	1
17	TPO	Thyroid Peroxidase	Protein Coding	1
18	TPH1	Tryptophan Hydroxylase 1	Protein Coding	1
19	TH	Tyrosine Hydroxylase	Protein Coding	1
20	TDO2	Tryptophan 2,3-Dioxygenase	Protein Coding	1
21	TAT	Tyrosine Aminotransferase	Protein Coding	1
22	SRM	Spermidine Synthase	Protein Coding	1
23	SMS	Spermine Synthase	Protein Coding	1
24	SDHA	Succinate Dehydrogenase Complex Flavoprotein Subunit A	Protein Coding	1
25	BHMT	Betaine--Homocysteine S-Methyltransferase	Protein Coding	1
26	RARS1	Arginyl-TRNA Synthetase 1	Protein Coding	1
27	BCAT1	Branched Chain Amino Acid Transaminase 1	Protein Coding	1
28	ALDH18A1	Aldehyde Dehydrogenase 18 Family Member A1	Protein Coding	1
29	PYCR1	Pyrroline-5-Carboxylate Reductase 1	Protein Coding	1
30	MCCC1	Methylcrotonyl-CoA Carboxylase Subunit 1	Protein Coding	1
31	AUH	AU RNA Binding Methylglutaconyl-CoA Hydratase	Protein Coding	1
32	PKM	Pyruvate Kinase M1/2	Protein Coding	1
33	PDK4	Pyruvate Dehydrogenase Kinase 4	Protein Coding	1
34	PDHA1	Pyruvate Dehydrogenase E1 Subunit Alpha 1	Protein Coding	1
35	PCK1	Phosphoenolpyruvate Carboxykinase 1	Protein Coding	1
36	PC	Pyruvate Carboxylase	Protein Coding	1
37	ALDH7A1	Aldehyde Dehydrogenase 7 Family Member A1	Protein Coding	1
38	OTC	Ornithine Transcarbamylase	Protein Coding	1
39	ACO2	Aconitase 2	Protein Coding	1
40	OGDH	Oxoglutarate Dehydrogenase	Protein Coding	1
41	ODC1	Ornithine Decarboxylase 1	Protein Coding	1
42	OAT	Ornithine Aminotransferase	Protein Coding	1
43	ACLY	ATP Citrate Lyase	Protein Coding	1
44	MMUT	Methylmalonyl-CoA Mutase	Protein Coding	1
45	ASS1	Argininosuccinate Synthase 1	Protein Coding	1
46	ASNS	Asparagine Synthetase (Glutamine-Hydrolyzing)	Protein Coding	1
47	MPST	Mercaptopyruvate Sulfurtransferase	Protein Coding	1
48	MDH2	Malate Dehydrogenase 2	Protein Coding	1
49	MDH1	Malate Dehydrogenase 1	Protein Coding	1
50	MAOA	Monoamine Oxidase A	Protein Coding	1
51	LDHA	Lactate Dehydrogenase A	Protein Coding	1
52	ARG2	Arginase 2	Protein Coding	1
53	ARG1	Arginase 1	Protein Coding	1
54	IDH1	Isocitrate Dehydrogenase (NADP(+)) 1	Protein Coding	1
55	ACADM	Acyl-CoA Dehydrogenase Medium Chain	Protein Coding	1
56	IARS1	Isoleucyl-TRNA Synthetase 1	Protein Coding	1
57	HNMT	Histamine N-Methyltransferase	Protein Coding	1
58	HMGCS2	3-Hydroxy-3-Methylglutaryl-CoA Synthase 2	Protein Coding	1
59	HMGCL	3-Hydroxy-3-Methylglutaryl-CoA Lyase	Protein Coding	1
60	HDC	Histidine Decarboxylase	Protein Coding	1
61	HADH	Hydroxyacyl-CoA Dehydrogenase	Protein Coding	1
62	GSS	Glutathione Synthetase	Protein Coding	1
63	GSR	Glutathione-Disulfide Reductase	Protein Coding	1
64	GOT1	Glutamic-Oxaloacetic Transaminase 1	Protein Coding	1
65	GLUL	Glutamate-Ammonia Ligase	Protein Coding	1
66	GLS	Glutaminase	Protein Coding	1
67	GCLM	Glutamate-Cysteine Ligase Modifier Subunit	Protein Coding	1
68	HIBCH	3-Hydroxyisobutyryl-CoA Hydrolase	Protein Coding	1
69	LARS2	Leucyl-TRNA Synthetase 2, Mitochondrial	Protein Coding	1
70	FH	Fumarate Hydratase	Protein Coding	1
71	FAH	Fumarylacetoacetate Hydrolase	Protein Coding	1
72	ALDH1A1	Aldehyde Dehydrogenase 1 Family Member A1	Protein Coding	1
73	EHHADH	Enoyl-CoA Hydratase And 3-Hydroxyacyl CoA Dehydrogenase	Protein Coding	1
74	DLD	Dihydrolipoamide Dehydrogenase	Protein Coding	1
75	DDC	Dopa Decarboxylase	Protein Coding	1
76	DBH	Dopamine Beta-Hydroxylase	Protein Coding	1
77	PPM1L	Protein Phosphatase, Mg2+/Mn2+ Dependent 1L	Protein Coding	1
78	CTH	Cystathionine Gamma-Lyase	Protein Coding	1
79	CS	Citrate Synthase	Protein Coding	1
80	CPS1	Carbamoyl-Phosphate Synthase 1	Protein Coding	1
81	ADH7	Alcohol Dehydrogenase 7 (Class IV), Mu Or Sigma Polypeptide	Protein Coding	1
82	ADH5	Alcohol Dehydrogenase 5 (Class III), Chi Polypeptide	Protein Coding	1
83	ADH4	Alcohol Dehydrogenase 4 (Class II), Pi Polypeptide	Protein Coding	1
84	ADH1C	Alcohol Dehydrogenase 1C (Class I), Gamma Polypeptide	Protein Coding	1
85	SDS	Serine Dehydratase	Protein Coding	1
86	FARSB	Phenylalanyl-TRNA Synthetase Subunit Beta	Protein Coding	1
87	HIBADH	3-Hydroxyisobutyrate Dehydrogenase	Protein Coding	1
88	VARS1	Valyl-TRNA Synthetase 1	Protein Coding	1
89	PNMT	Phenylethanolamine N-Methyltransferase	Protein Coding	1
90	GOT2	Glutamic-Oxaloacetic Transaminase 2	Protein Coding	1
91	EPRS1	Glutamyl-Prolyl-TRNA Synthetase 1	Protein Coding	1

Disorders associated with Amino acid metabolism SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Hereditary paraganglioma-pheochromocytoma syndromes	Enrichment	DLST, FH, MDH2, SDHA	4.98
2	Pyruvate dehydrogenase e1-alpha deficiency	Enrichment	PDHA1, PDHX	3.58
3	Tyrosinemia, type ii	Enrichment	FAH, TAT	3.58
4	Histidinemia	Enrichment	HAL	3.53
5	Hyperinsulinemic hypoglycemia, familial, 6	Enrichment	GLUD1	3.53
6	Glutamate formiminotransferase deficiency	Enrichment	FTCD	3.23
7	Spastic paraplegia 73, autosomal dominant	Enrichment	GPT2	3.23
8	Neurodevelopmental disorder with spastic paraplegia and microcephaly	Enrichment	GPT2	3.23
9	Hyperinsulinemic hypoglycemia, familial, 1	Enrichment	GLUD1, HADH	3.18
10	Nonsyndromic genetic hyperinsulinism	Enrichment	GLUD1, HADH	3.18
11	Rare genetic intellectual disability	Enrichment	GPT2	2.35
12	Hereditary leiomyomatosis and renal cell cancer	Enrichment	FH	2.17
13	Cystathioninuria	Enrichment	CTH	2.17
14	3-hydroxyacyl-coa dehydrogenase deficiency	Enrichment	HADH	2.17
15	Mitochondrial dna depletion syndrome 9	Enrichment	SUCLG1	2.17
16	Oxoglutarate dehydrogenase deficiency	Enrichment	OGDH	2.17
17	Phosphoenolpyruvate carboxykinase deficiency, cytosolic	Enrichment	PCK1	2.17
18	Epilepsy, early-onset, 4, vitamin b6-dependent	Enrichment	ALDH7A1	2.17
19	Glutathione synthetase deficiency	Enrichment	GSS	2.17
20	Spastic paraplegia 9a, autosomal dominant	Enrichment	ALDH18A1	2.17
21	T-substance anomaly	Enrichment	FAH	2.17
22	Fumarase deficiency	Enrichment	FH	2.17
23	Rajab interstitial lung disease with brain calcifications 1	Enrichment	FARSB	2.17
24	Anemia, congenital, nonspherocytic hemolytic, 6	Enrichment	GSS	2.17
25	3-hydroxyisobutyryl-coa hydrolase deficiency	Enrichment	HIBCH	2.17
26	Cutis laxa, autosomal recessive, type iiia	Enrichment	ALDH18A1	2.17
27	3-hydroxy-3-methylglutaryl-coa lyase deficiency	Enrichment	HMGCL	2.17
28	Myopia 25, autosomal dominant	Enrichment	P4HA2	2.17
29	Pheochromocytoma/paraganglioma syndrome 5	Enrichment	SDHA	2.17
30	Cutis laxa, autosomal recessive, type iiib	Enrichment	PYCR1	2.17
31	Intellectual developmental disorder, autosomal recessive 51	Enrichment	HNMT	2.17
32	Acyl-coa dehydrogenase, medium-chain, deficiency of	Enrichment	ACADM	2.17
33	Anemia, congenital, nonspherocytic hemolytic, 10	Enrichment	GSR	2.17
34	Fanconi renotubular syndrome 3	Enrichment	EHHADH	2.17
35	Spastic paraplegia 9b, autosomal recessive	Enrichment	ALDH18A1	2.17
36	Casgid syndrome	Enrichment	GLS	2.17
37	Bachmann-bupp syndrome	Enrichment	ODC1	2.17
38	Hyperhomocysteinemia	Enrichment	CBS	2.17
39	Ornithine transcarbamylase deficiency, hyperammonemia due to	Enrichment	OTC	2.17
40	Pheochromocytoma/paraganglioma syndrome 7	Enrichment	DLST	2.17
41	Brunner syndrome	Enrichment	MAOA	2.17
42	Intellectual developmental disorder, x-linked, syndromic, snyder-robinson type	Enrichment	SMS	2.17
43	Hypertryptophanemia	Enrichment	TDO2	2.17
44	Cutis laxa, autosomal dominant 3	Enrichment	ALDH18A1	2.17
45	Growth retardation, impaired intellectual development, hypotonia, and hepatopathy	Enrichment	IARS1	2.17
46	Leukodystrophy, hypomyelinating, 9	Enrichment	RARS1	2.17
47	Leiomyoma cutis	Enrichment	FH	2.17
48	Developmental and epileptic encephalopathy 71	Enrichment	GLS	2.17
49	Aspartate aminotransferase, serum level of, quantitative trait locus 1	Enrichment	GOT1	2.17
50	Cardiomyopathy, dilated, 1gg	Enrichment	SDHA	2.17
51	Metaphyseal enchondromatosis with d-2-hydroxyglutaric aciduria	Enrichment	IDH1	2.17
52	Combined oxidative phosphorylation deficiency 25	Enrichment	MARS2	2.17
53	Pulmonary hypertension, neonatal	Enrichment	CPS1	2.17
54	Autosomal recessive cutis laxa type iii	Enrichment	ALDH18A1	2.17
55	Cutis laxa, autosomal recessive, type iib	Enrichment	PYCR1	2.17
56	Developmental and epileptic encephalopathy 51	Enrichment	MDH2	2.17
57	Syndromic x-linked intellectual disability snyder type	Enrichment	SMS	2.17
58	Fumarate hydratase deficiency	Enrichment	FH	2.17
59	Neurodegeneration with ataxia and late-onset optic atrophy	Enrichment	SDHA	2.17
60	Neuronopathy, distal hereditary motor, autosomal dominant 9	Enrichment	WARS1	2.17
61	Neurodevelopmental disorder with microcephaly and speech delay, with or without brain abnormalities	Enrichment	WARS1	2.17
62	Leukodystrophy, hypomyelinating, 15	Enrichment	EPRS1	2.17
63	Choroid disease	Enrichment	OAT	2.17
64	Developmental and epileptic encephalopathy 116	Enrichment	GLUL	2.17
65	Spastic ataxia-dysarthria due to glutaminase deficiency	Enrichment	GLS	2.17
66	Brain calcification, rajab type	Enrichment	FARSB	2.17
67	Medium-chain acyl-coenzyme a dehydrogenase deficiency	Enrichment	ACADM	2.17
68	Disorder of ornithine metabolism	Enrichment	OTC	2.17
69	Liver cirrhosis	Enrichment	FARSB	2.17
70	Suclg1-related mitochondrial dna depletion syndrome, encephalomyopathic form with methylmalonic aciduria	Enrichment	SUCLG1	2.17
71	Autosomal dominant complex spastic paraplegia type 9b	Enrichment	ALDH18A1	2.17
72	Developmental and epileptic encephalopathy 1	Enrichment	CAD, MDH2	1.92
73	Gilles de la tourette syndrome	Enrichment	HDC	1.87
74	Leiomyoma, uterine	Enrichment	FH	1.87
75	Fanconi-bickel syndrome	Enrichment	LDHA	1.87
76	Citrullinemia, classic	Enrichment	ASS1	1.87
77	Carbamoyl phosphate synthetase i deficiency, hyperammonemia due to	Enrichment	CPS1	1.87
78	Argininemia	Enrichment	ARG1	1.87
79	3-methylcrotonyl-coa carboxylase 1 deficiency	Enrichment	MCCC1	1.87
80	Dihydrolipoamide dehydrogenase deficiency	Enrichment	DLD	1.87
81	Polymyoclonus, infantile	Enrichment	SDHA	1.87
82	Tyrosinemia, type i	Enrichment	FAH	1.87
83	Porphyria, acute intermittent	Enrichment	ACO2	1.87
84	Glutamine deficiency, congenital	Enrichment	GLUL	1.87
85	Hyperinsulinemic hypoglycemia, familial, 4	Enrichment	HADH	1.87
86	Spastic ataxia 3, autosomal recessive	Enrichment	MARS2	1.87
87	Segawa syndrome, autosomal recessive	Enrichment	TH	1.87
88	Orthostatic hypotension 1	Enrichment	DBH	1.87
89	Methemoglobinemia due to deficiency of methemoglobin reductase	Enrichment	DLD	1.87
90	Developmental and epileptic encephalopathy 50	Enrichment	CAD	1.87
91	Hydrops, lactic acidosis, and sideroblastic anemia	Enrichment	LARS2	1.87
92	Aromatic l-amino acid decarboxylase deficiency	Enrichment	DDC	1.87
93	Pyruvate dehydrogenase e3-binding protein deficiency	Enrichment	PDHX	1.87
94	Amed syndrome, digenic	Enrichment	ADH5	1.87
95	Global developmental delay, progressive ataxia, and elevated glutamine	Enrichment	GLS	1.87
96	Developmental and epileptic encephalopathy 82	Enrichment	GOT2	1.87
97	Spastic paraplegia 5a, autosomal recessive	Enrichment	ALDH18A1	1.87
98	Developmental and epileptic encephalopathy 88	Enrichment	MDH1	1.87
99	Thyroid dyshormonogenesis 2a	Enrichment	TPO	1.87
100	3-hydroxy-3-methylglutaryl-coa synthase-2 deficiency	Enrichment	HMGCS2	1.87
101	Spastic ataxia 3	Enrichment	MARS2	1.87
102	3-methylcrotonyl-coa carboxylase deficiency	Enrichment	MCCC1	1.87
103	Developmental and epileptic encephalopathy 16	Enrichment	GLUL	1.87
104	Dopamine beta-hydroxylase deficiency	Enrichment	DBH	1.87
105	Acute porphyria	Enrichment	ACO2	1.87
106	Interstitial lung and liver disease	Enrichment	FARSB	1.87
107	Perrault syndrome 4	Enrichment	LARS2	1.87
108	Spinocerebellar ataxia 45	Enrichment	FH	1.87
109	Congenital brain dysgenesis due to glutamine synthetase deficiency	Enrichment	GLUL	1.87
110	Citrullinemia	Enrichment	ASS1	1.87
111	Pyridoxine-dependent-developmental and epileptic encephalopathy	Enrichment	ALDH7A1	1.87
112	Connective tissue disease	Enrichment	CBS, PYCR1	1.71
113	Dystonia, dopa-responsive	Enrichment	TH	1.70
114	Mannosidosis, beta a, lysosomal	Enrichment	FAH	1.70
115	Homocystinuria due to cystathionine beta-synthase deficiency	Enrichment	CBS	1.70
116	3-methylglutaconic aciduria, type i	Enrichment	AUH	1.70
117	Geroderma osteodysplasticum	Enrichment	PYCR1	1.70
118	D-bifunctional protein deficiency	Enrichment	EHHADH	1.70
119	Pyruvate carboxylase deficiency	Enrichment	PC	1.70
120	Methylmalonic aciduria due to methylmalonyl-coa mutase deficiency	Enrichment	MMUT	1.70
121	Citrin deficiency, adolescent or adult onset	Enrichment	ASS1	1.70
122	Carney triad	Enrichment	SDHA	1.70
123	Long-chain 3-hydroxyacyl-coa dehydrogenase deficiency	Enrichment	HMGCL	1.70
124	Developmental and epileptic encephalopathy 13	Enrichment	ALDH7A1	1.70
125	Infantile cerebellar-retinal degeneration	Enrichment	ACO2	1.70
126	Optic atrophy 9	Enrichment	ACO2	1.70
127	Paraganglioma	Enrichment	SDHA	1.70
128	Neurodevelopmental disorder with microcephaly, seizures, and cortical atrophy	Enrichment	VARS1	1.70
129	Gyrate atrophy of choroid and retina	Enrichment	OAT	1.70
130	Autosomal dominant cutis laxa	Enrichment	ALDH18A1	1.70
131	Hyperinsulinemic hypoglycemia	Enrichment	HADH	1.70
132	Asparagine synthetase deficiency	Enrichment	ASNS	1.70
133	Brain cancer	Enrichment	SDHA	1.70
134	3-methylglutaconic aciduria	Enrichment	AUH	1.70
135	Congenital microcephaly - severe encephalopathy - progressive cerebral atrophy syndrome	Enrichment	ASNS	1.70
136	Phosphoenolpyruvate carboxykinase deficiency	Enrichment	PCK1	1.70
137	Spinocerebellar ataxia, autosomal recessive 29	Enrichment	ASNS	1.70
138	Homocystinuria	Enrichment	CBS	1.70
139	Enchondromatosis	Enrichment	IDH1	1.70
140	Tyrosinemia	Enrichment	FAH	1.70
141	Pheochromocytoma/paraganglioma syndrome 1	Enrichment	SDHA	1.58
142	Mitochondrial complex ii deficiency, nuclear type 1	Enrichment	SDHA	1.58
143	Glycogen storage disease ia	Enrichment	ASS1	1.58
144	Temporal arteritis	Enrichment	P4HA2	1.58
145	Parkinson disease, mitochondrial	Enrichment	ADH1C	1.58
146	Pilocytic astrocytoma	Enrichment	SDHA	1.58
147	Hydrocephalus, congenital, 2, with or without brain or eye anomalies	Enrichment	ACADM	1.58
148	Mitochondrial complex ii deficiency	Enrichment	SDHA	1.58
149	Primary fanconi renotubular syndrome	Enrichment	EHHADH	1.58
150	Autosomal recessive isolated optic atrophy	Enrichment	ACO2	1.58
151	Enchondromatosis, multiple, ollier type	Enrichment	IDH1	1.48
152	Paroxysmal extreme pain disorder	Enrichment	IDH1	1.48
153	Smith-magenis syndrome	Enrichment	SMS	1.48
154	Liver failure, infantile, transient	Enrichment	MMUT	1.48
155	Optic atrophy plus syndrome	Enrichment	ACO2, OAT	1.45
156	Alcohol dependence	Enrichment	ADH1C	1.40
157	Familial thyroid dyshormonogenesis	Enrichment	TPO	1.40
158	Pain disorder	Enrichment	OAT	1.40
159	Gastrointestinal stromal tumor	Enrichment	SDHA	1.34
160	Multiple enchondromatosis, maffucci type	Enrichment	IDH1	1.34
161	Isolated methylmalonic acidemia	Enrichment	MMUT	1.34
162	Glioma susceptibility 1	Enrichment	IDH1	1.28
163	Perrault syndrome	Enrichment	LARS2	1.28
164	Methylmalonic acidemia	Enrichment	MMUT	1.28
165	Perrault syndrome 2	Enrichment	LARS2	1.23
166	Asthma	Enrichment	HNMT	1.15
167	Mitochondrial myopathy	Enrichment	LARS2	1.15
168	Congenital hypothyroidism	Enrichment	TPO	1.11
169	Cutis laxa	Enrichment	PYCR1	1.11
170	Lactic acidosis	Enrichment	DLD	1.11
171	Pheochromocytoma	Enrichment	SDHA	1.05
172	Isolated macular dystrophy	Enrichment	ACO2	1.05
173	Hydrocephalus, congenital, 1	Enrichment	ALDH7A1	0.99
174	Perrault syndrome 1	Enrichment	LARS2	0.99
175	Rhabdomyosarcoma	Enrichment	SDHA	0.99
176	Gliosarcoma	Enrichment	IDH1	0.99
177	Sudden infant death syndrome	Enrichment	PDHA1	0.97
178	Giant cell glioblastoma	Enrichment	IDH1	0.97
179	Esophageal atresia/tracheoesophageal fistula	Enrichment	GLS	0.92
180	Leukodystrophy	Enrichment	RARS1	0.90
181	Hepatocellular carcinoma	Enrichment	FH	0.86
182	Myocardial infarction	Enrichment	GCLM	0.86
183	Parkinson disease, late-onset	Enrichment	ADH1C	0.83
184	Congenital nervous system abnormality	Enrichment	ALDH18A1, ALDH7A1	0.80
185	Nervous system disease	Enrichment	ALDH18A1, ALDH7A1	0.80
186	Rasopathy	Enrichment	DDC	0.79
187	Primary autosomal recessive microcephaly	Enrichment	WARS1	0.71
188	Dystonia	Enrichment	TH	0.68
189	Developmental and epileptic encephalopathy	Enrichment	GOT2	0.67
190	Non-syndromic genetic deafness	Enrichment	LARS2	0.67
191	Inherited cancer-predisposing syndrome	Enrichment	FH, SDHA	0.65
192	Leukemia, acute myeloid	Enrichment	IDH1	0.63
193	Epilepsy	Enrichment	ALDH7A1	0.63
194	Hereditary spastic paraplegia	Enrichment	ALDH18A1	0.61
195	Nonsyndromic hearing loss	Enrichment	LARS2	0.61
196	West syndrome	Enrichment	MDH2	0.59
197	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	CBS	0.59
198	Hereditary breast carcinoma	Enrichment	SDHA	0.59
199	Familial isolated dilated cardiomyopathy	Enrichment	SDHA	0.52
200	Hereditary breast ovarian cancer syndrome	Enrichment	CPS1	0.51
201	Autosomal recessive non-syndromic intellectual disability	Enrichment	HNMT	0.49
202	Leigh syndrome, nuclear	Enrichment	SDHA	0.43
203	Breast cancer	Enrichment	SDHA	0.40
204	Leigh disease	Enrichment	SDHA	0.40
205	Rare genetic deafness	Enrichment	LARS2	0.38
206	Mitochondrial disease	Enrichment	PDHX	0.35
207	Ovarian cancer	Enrichment	FH	0.31
208	Microcephaly	Enrichment	IARS1	0.25
209	Complex neurodevelopmental disorder	Enrichment	WARS1	0.25
210	Hereditary retinal dystrophy	Enrichment	ACO2, OAT	0.23
211	Fundus dystrophy	Enrichment	ACO2, OAT	0.23

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Amino acid metabolism

Pathway Network for Amino acid metabolism

Member Pathways for Amino acid metabolism

Pathways in the Amino acid metabolism SuperPath

Associated Genes for Amino acid metabolism

Associated Disorders for Amino acid metabolism

Disorders associated with Amino acid metabolism SuperPath

STRING Interaction Network for Amino acid metabolism

Sources for Amino acid metabolism