Anandamide biosynthesis and metabolism

No Pathway Network information available for Anandamide biosynthesis and metabolism

Pathways in the Anandamide biosynthesis and metabolism SuperPath

#	Name	Source	Genes
1	Anandamide biosynthesis and metabolism	GeneGo (Thomson Reuters)	ENPP2 FAAH NAPEPLD PLA2G10 PLA2G1B PLA2G2A PLA2G4A PLA2G5 PLAAT5 PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PTPN22 (see all 21) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	FAAH	Fatty Acid Amide Hydrolase	Protein Coding	1
2	ENPP2	Ectonucleotide Pyrophosphatase/Phosphodiesterase 2	Protein Coding	1
3	PLA2G1B	Phospholipase A2 Group IB	Protein Coding	1
4	PLA2G2A	Phospholipase A2 Group IIA	Protein Coding	1
5	PLA2G4A	Phospholipase A2 Group IVA	Protein Coding	1
6	PLA2G5	Phospholipase A2 Group V	Protein Coding	1
7	PLCB2	Phospholipase C Beta 2	Protein Coding	1
8	PLCB3	Phospholipase C Beta 3	Protein Coding	1
9	PLCB4	Phospholipase C Beta 4	Protein Coding	1
10	PLCD1	Phospholipase C Delta 1	Protein Coding	1
11	PLCG1	Phospholipase C Gamma 1	Protein Coding	1
12	PLCG2	Phospholipase C Gamma 2	Protein Coding	1
13	PLA2G10	Phospholipase A2 Group X	Protein Coding	1
14	PLCB1	Phospholipase C Beta 1	Protein Coding	1
15	PTPN22	Protein Tyrosine Phosphatase Non-Receptor Type 22	Protein Coding	1
16	PLCE1	Phospholipase C Epsilon 1	Protein Coding	1
17	PLCD4	Phospholipase C Delta 4	Protein Coding	1
18	PLCZ1	Phospholipase C Zeta 1	Protein Coding	1
19	PLCD3	Phospholipase C Delta 3	Protein Coding	1
20	PLAAT5	Phospholipase A And Acyltransferase 5	Protein Coding	1
21	NAPEPLD	N-Acyl Phosphatidylethanolamine Phospholipase D	Protein Coding	1

Disorders associated with Anandamide biosynthesis and metabolism SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Polysubstance abuse	Enrichment	FAAH	2.81
2	Nail disorder, nonsyndromic congenital, 3	Enrichment	PLCD1	2.81
3	Fleck retina, familial benign	Enrichment	PLA2G5	2.81
4	Spondylometaphyseal dysplasia with corneal dystrophy	Enrichment	PLCB3	2.81
5	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	2.81
6	Auriculocondylar syndrome 2a	Enrichment	PLCB4	2.81
7	Cytosolic phospholipase-a2 alpha deficiency associated bleeding disorder	Enrichment	PLA2G4A	2.81
8	Autoinflammation, antibody deficiency, and immune dysregulation	Enrichment	PLCG2	2.81
9	Familial cold autoinflammatory syndrome 3	Enrichment	PLCG2	2.81
10	Gastrointestinal ulceration, recurrent, with dysfunctional platelets	Enrichment	PLA2G4A	2.81
11	Auriculocondylar syndrome 2b	Enrichment	PLCB4	2.81
12	Cryptogenic multifocal ulcerous stenosing enteritis	Enrichment	PLA2G4A	2.81
13	Familial benign flecked retina	Enrichment	PLA2G5	2.81
14	Spermatogenic failure 17	Enrichment	PLCZ1	2.51
15	Ocular melanoma	Enrichment	PLCB4	2.51
16	Late-onset retinal degeneration	Enrichment	PLA2G5	2.33
17	Nephrotic syndrome, type 3	Enrichment	PLCE1	2.33
18	Vogt-koyanagi-harada disease	Enrichment	PTPN22	2.33
19	Temporal arteritis	Enrichment	PTPN22	2.21
20	Auriculocondylar syndrome 1	Enrichment	PLCB4	2.21
21	Developmental and epileptic encephalopathy 12	Enrichment	PLCB1	2.21
22	Melanoma, uveal	Enrichment	PLCB4	2.03
23	Granulomatosis with polyangiitis	Enrichment	PTPN22	2.03
24	Oligoarticular juvenile idiopathic arthritis	Enrichment	PTPN22	1.97
25	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	PTPN22	1.97
26	Nephrotic syndrome, type 1	Enrichment	PLCE1	1.86
27	Developmental and epileptic encephalopathy 14	Enrichment	PLCB1	1.86
28	Familial colorectal cancer	Enrichment	PLA2G2A	1.81
29	Focal segmental glomerulosclerosis	Enrichment	PLCE1	1.52
30	Genetic steroid-resistant nephrotic syndrome	Enrichment	PLCE1	1.29
31	Systemic lupus erythematosus	Enrichment	PTPN22	1.23
32	Benign epilepsy with centrotemporal spikes	Enrichment	PLCB1	1.21
33	Centralopathic epilepsy	Enrichment	PLCB1	1.19
34	Nephrotic syndrome	Enrichment	PLCE1	1.19
35	West syndrome	Enrichment	PLCB1	1.18
36	Colorectal cancer	Enrichment	PLA2G2A	0.90

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Anandamide biosynthesis and metabolism

Pathway Network for Anandamide biosynthesis and metabolism

Member Pathways for Anandamide biosynthesis and metabolism

Pathways in the Anandamide biosynthesis and metabolism SuperPath

Associated Genes for Anandamide biosynthesis and metabolism

Associated Disorders for Anandamide biosynthesis and metabolism

Disorders associated with Anandamide biosynthesis and metabolism SuperPath

STRING Interaction Network for Anandamide biosynthesis and metabolism

Sources for Anandamide biosynthesis and metabolism