Androgen receptor network in prostate cancer

Pathway network for the Androgen receptor network in prostate cancer SuperPath

Sources:

WikiPathways

Pathways in the Androgen receptor network in prostate cancer SuperPath

#	Name	Source	Genes
1	Androgen receptor network in prostate cancer	WikiPathways	ABCC4 ACTL6A ACTL6B AKT1 AR ARID1A ARID1B ATF1 ATM ATR BAD BARD1 BAX BCL2 BLM BRCA1 CASP3 CASP8 CASP9 CCND1 CDC25A CDC25B CDK1 CDK2 CDK4 CHEK1 CHEK2 CPN1 CRK CRKL CYP17A1 DOCK1 E2F1 EIF4E1B EIF4EBP1 ELK1 ERG ETV4 F13B FOS GAB1 GRB2 HGF HRAS HSD17B1 HSD17B2 HSD17B3 HSD17B4 HSD17B7 HSD3B1 HSD3B2 JAK1 JUN KLK2 KLK3 MAP2K1 MAP2K2 MAP4K1 MAPK1 MAPK14 MAPK3 MAPK8 MDM2 MMP1 MRE11 MSH2 MSH6 MTOR MYC NDRG1 NOXA1 PAK1 PIK3CA PLK1 PRKDC PTEN PTK2B PTPN11 PXN RAD50 RAF1 RAP1A RAP1B RAPGEF1 RASA1 RB1 RHEB RPTOR SMAD2 SMAD3 SMARCA4 SMARCC1 SMARCC2 SMARCD1 SMARCD2 SMARCD3 SOS1 SPINK1 SPRY1 SPRY2 STAT1 STAT3 TP53 TSC1 TSC2 (see all 105) (see less)
2	Integrated cancer pathway	WikiPathways	AKT1 ATF1 ATM ATR BAD BARD1 BAX BCL2 BLM BRCA1 CASP3 CASP8 CASP9 CDC25A CDC25B CDK1 CDK2 CDK4 CHEK1 CHEK2 E2F1 GRIK1-AS2 JAK1 MDM2 MMP1 MRE11 MSH2 MSH6 MYC NOXA1 PLK1 PTEN RAD50 RB1 SMAD2 SMAD3 STAT1 TP53 (see all 38) (see less)
3	Steroid biosynthesis	WikiPathways	CPN1 CYP17A1 F13B HSD17B1 HSD17B2 HSD17B3 HSD17B4 HSD17B7 HSD3B1 HSD3B2 (see all 10) (see less)

Gene overlap in member pathways for Androgen receptor network in prostate cancer SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	NOXA1	NADPH Oxidase Activator 1	Protein Coding	2
2	BARD1	BRCA1 Associated RING Domain 1	Protein Coding	2
3	CHEK2	Checkpoint Kinase 2	Protein Coding	2
4	E2F1	E2F Transcription Factor 1	Protein Coding	2
5	BCL2	BCL2 Apoptosis Regulator	Protein Coding	2
6	CASP8	Caspase 8	Protein Coding	2
7	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	2
8	RAD50	RAD50 Double Strand Break Repair Protein	Protein Coding	2
9	BRCA1	BRCA1 DNA Repair Associated	Protein Coding	2
10	MRE11	MRE11 Double Strand Break Repair Nuclease	Protein Coding	2
11	BLM	BLM RecQ Like Helicase	Protein Coding	2
12	CDK2	Cyclin Dependent Kinase 2	Protein Coding	2
13	MMP1	Matrix Metallopeptidase 1	Protein Coding	2
14	RB1	RB Transcriptional Corepressor 1	Protein Coding	2
15	CDK4	Cyclin Dependent Kinase 4	Protein Coding	2
16	SMAD2	SMAD Family Member 2	Protein Coding	2
17	SMAD3	SMAD Family Member 3	Protein Coding	2
18	CDK1	Cyclin Dependent Kinase 1	Protein Coding	2
19	BAD	BCL2 Associated Agonist Of Cell Death	Protein Coding	2
20	MDM2	MDM2 Proto-Oncogene	Protein Coding	2
21	ATR	ATR Checkpoint Kinase	Protein Coding	2
22	CHEK1	Checkpoint Kinase 1	Protein Coding	2
23	ATM	ATM Serine/Threonine Kinase	Protein Coding	2
24	TP53	Tumor Protein P53	Protein Coding	2
25	STAT1	Signal Transducer And Activator Of Transcription 1	Protein Coding	2
26	JAK1	Janus Kinase 1	Protein Coding	2
27	CASP9	Caspase 9	Protein Coding	2
28	CASP3	Caspase 3	Protein Coding	2
29	BAX	BCL2 Associated X, Apoptosis Regulator	Protein Coding	2
30	MSH2	MutS Homolog 2	Protein Coding	2
31	MSH6	MutS Homolog 6	Protein Coding	2
32	HSD17B7	Hydroxysteroid 17-Beta Dehydrogenase 7	Protein Coding	2
33	CDC25B	Cell Division Cycle 25B	Protein Coding	2
34	PTEN	Phosphatase And Tensin Homolog	Protein Coding	2
35	PLK1	Polo Like Kinase 1	Protein Coding	2
36	ATF1	Activating Transcription Factor 1	Protein Coding	2
37	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	2
38	HSD17B4	Hydroxysteroid 17-Beta Dehydrogenase 4	Protein Coding	2
39	HSD17B2	Hydroxysteroid 17-Beta Dehydrogenase 2	Protein Coding	2
40	HSD17B3	Hydroxysteroid 17-Beta Dehydrogenase 3	Protein Coding	2
41	HSD17B1	Hydroxysteroid 17-Beta Dehydrogenase 1	Protein Coding	2
42	HSD3B2	Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- And Steroid Delta-Isomerase 2	Protein Coding	2
43	HSD3B1	Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- And Steroid Delta-Isomerase 1	Protein Coding	2
44	F13B	Coagulation Factor XIII B Chain	Protein Coding	2
45	CYP17A1	Cytochrome P450 Family 17 Subfamily A Member 1	Protein Coding	2
46	CPN1	Carboxypeptidase N Subunit 1	Protein Coding	2
47	CDC25A	Cell Division Cycle 25A	Protein Coding	2
48	EIF4E1B	Eukaryotic Translation Initiation Factor 4E Family Member 1B	Protein Coding	1
49	RPTOR	Regulatory Associated Protein Of MTOR Complex 1	Protein Coding	1
50	RHEB	Ras Homolog, MTORC1 Binding	Protein Coding	1
51	CCND1	Cyclin D1	Protein Coding	1
52	TSC1	TSC Complex Subunit 1	Protein Coding	1
53	TSC2	TSC Complex Subunit 2	Protein Coding	1
54	PRKDC	Protein Kinase, DNA-Activated, Catalytic Subunit	Protein Coding	1
55	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	1
56	RAP1B	RAP1B, Member Of RAS Oncogene Family	Protein Coding	1
57	RAP1A	RAP1A, Member Of RAS Oncogene Family	Protein Coding	1
58	ARID1A	AT-Rich Interaction Domain 1A	Protein Coding	1
59	STAT3	Signal Transducer And Activator Of Transcription 3	Protein Coding	1
60	SPINK1	Serine Peptidase Inhibitor Kazal Type 1	Protein Coding	1
61	SOS1	SOS Ras/Rac Guanine Nucleotide Exchange Factor 1	Protein Coding	1
62	SMARCD2	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit D2	Protein Coding	1
63	SMARCC1	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit C1	Protein Coding	1
64	SMARCA4	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit ATPase 4	Protein Coding	1
65	RASA1	RAS P21 Protein Activator 1	Protein Coding	1
66	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
67	PXN	Paxillin	Protein Coding	1
68	PTPN11	Protein Tyrosine Phosphatase Non-Receptor Type 11	Protein Coding	1
69	ARID1B	AT-Rich Interaction Domain 1B	Protein Coding	1
70	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	1
71	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	1
72	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	1
73	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	1
74	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
75	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
76	ACTL6B	Actin Like 6B	Protein Coding	1
77	PAK1	P21 (RAC1) Activated Kinase 1	Protein Coding	1
78	KLK2	Kallikrein Related Peptidase 2	Protein Coding	1
79	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
80	AR	Androgen Receptor	Protein Coding	1
81	KLK3	Kallikrein Related Peptidase 3	Protein Coding	1
82	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	1
83	HGF	Hepatocyte Growth Factor	Protein Coding	1
84	GAB1	GRB2 Associated Binding Protein 1	Protein Coding	1
85	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
86	PTK2B	Protein Tyrosine Kinase 2 Beta	Protein Coding	1
87	ETV4	ETS Variant Transcription Factor 4	Protein Coding	1
88	ERG	ETS Transcription Factor ERG	Protein Coding	1
89	EIF4EBP1	Eukaryotic Translation Initiation Factor 4E Binding Protein 1	Protein Coding	1
90	DOCK1	Dedicator Of Cytokinesis 1	Protein Coding	1
91	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
92	CRKL	CRK Like Proto-Oncogene, Adaptor Protein	Protein Coding	1
93	CRK	CRK Proto-Oncogene, Adaptor Protein	Protein Coding	1
94	NDRG1	N-Myc Downstream Regulated 1	Protein Coding	1
95	ABCC4	ATP Binding Cassette Subfamily C Member 4 (PEL Blood Group)	Protein Coding	1
96	SPRY2	Sprouty RTK Signaling Antagonist 2	Protein Coding	1
97	ACTL6A	Actin Like 6A	Protein Coding	1
98	MAP4K1	Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1	Protein Coding	1
99	SPRY1	Sprouty RTK Signaling Antagonist 1	Protein Coding	1
100	SMARCD3	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit D3	Protein Coding	1
101	SMARCD1	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit D1	Protein Coding	1
102	SMARCC2	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit C2	Protein Coding	1
103	RAPGEF1	Rap Guanine Nucleotide Exchange Factor 1	Protein Coding	1
104	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	1
105	ELK1	ETS Transcription Factor ELK1	Protein Coding	1
106	GRIK1-AS2	GRIK1 Antisense RNA 2	RNA Gene	1

Disorders associated with Androgen receptor network in prostate cancer SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Breast cancer	Enrichment	AKT1, ATM, BARD1, BLM, BRCA1, CASP8, CHEK2, CYP17A1, JUN, MRE11, MSH2, MSH6, PIK3CA, PTEN, RAD50, TP53	16.00
2	Ovarian cancer	Enrichment	AKT1, ATM, BARD1, BLM, BRCA1, CHEK2, MRE11, MSH2, MSH6, PTEN, RAD50, RB1, TP53	16.00
3	Hereditary breast carcinoma	Enrichment	AKT1, ATM, BARD1, BLM, BRCA1, CHEK2, MSH2, MSH6, PTEN, RAD50, TP53	16.00
4	Hereditary breast ovarian cancer syndrome	Enrichment	ATM, BARD1, BLM, BRCA1, CHEK2, MRE11, MSH2, MSH6, PTEN, RAD50, TP53	11.69
5	Colorectal cancer	Enrichment	AKT1, ATM, BAX, BLM, BRCA1, CHEK2, MSH2, MSH6, TP53	11.55
6	Endometrial cancer	Enrichment	ATM, BARD1, BLM, BRCA1, CHEK2, MSH2, MSH6, PIK3CA, PTEN	11.47
7	Gastric cancer	Enrichment	ATM, BARD1, BRCA1, CDK4, CHEK2, MSH2, MSH6, PTEN, TP53	11.45
8	Uterine corpus cancer	Enrichment	ATM, BRCA1, CHEK2, MSH2, MSH6, PTEN	11.00
9	Inherited cancer-predisposing syndrome	Enrichment	ATM, BARD1, BLM, BRCA1, CDK4, CHEK2, MRE11, MSH2, MSH6, PTEN, RAD50, RB1, TP53	10.67
10	Bladder cancer	Enrichment	ARID1A, ATM, BRCA1, HRAS, PIK3CA, PTEN, RB1, TP53, TSC1	10.65
11	Prostate cancer	Enrichment	AR, ATM, BRCA1, CHEK2, MSH6, PIK3CA, PTEN, TP53	10.23
12	Rhabdomyosarcoma	Enrichment	BRCA1, MSH2, MSH6, PTEN, TP53	9.23
13	Noonan syndrome and noonan-related syndrome	Enrichment	HRAS, MAP2K1, MAP2K2, PTPN11, RAF1, SOS1	9.05
14	Adult hepatocellular carcinoma	Enrichment	CASP8, PIK3CA, TP53, TSC1, TSC2	8.50
15	Focal cortical dysplasia, type ii	Enrichment	MTOR, RHEB, TSC1, TSC2	8.47
16	Isolated focal cortical dysplasia type ii	Enrichment	MTOR, RHEB, TSC1, TSC2	8.47
17	Lynch syndrome 1	Enrichment	ATM, CHEK2, MSH2, MSH6	7.96
18	Hemimegalencephaly	Enrichment	MTOR, PIK3CA, PTEN, RHEB	7.77
19	Noonan syndrome 1	Enrichment	HRAS, MAP2K1, MAP2K2, PTPN11, RAF1, SOS1	7.77
20	Osteogenic sarcoma	Enrichment	CHEK2, RB1, TP53	7.69
21	Bone osteosarcoma	Enrichment	CHEK2, RB1, TP53	7.69
22	Breast-ovarian cancer, familial 1	Enrichment	ATM, BRCA1, CHEK2, MSH2	7.43
23	Rasopathy	Enrichment	HRAS, MAP2K1, MAP2K2, PTPN11, RAF1, SOS1	7.42
24	Coffin-siris syndrome 1	Enrichment	ARID1A, ARID1B, SMARCA4, SMARCC2, SMARCD1	7.15
25	Lynch syndrome 4	Enrichment	MSH2, MSH6, RB1	7.09
26	Noonan syndrome 3	Enrichment	HRAS, PTPN11, RAF1, SOS1	6.93
27	Li-fraumeni syndrome	Enrichment	CHEK2, MDM2, TP53	6.39
28	Arteriovenous malformation	Enrichment	HRAS, MAP2K1, PIK3CA, RASA1	6.38
29	Pancreatic cancer	Enrichment	ATM, BRCA1, CHEK2, TP53	6.20
30	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS, MAP2K1, PIK3CA, RASA1	6.16
31	Lip and oral cavity carcinoma	Enrichment	HRAS, PIK3CA, RB1, TP53	5.80
32	Colonic benign neoplasm	Enrichment	ATM, CHEK2, MRE11	5.77
33	Lynch syndrome	Enrichment	CHEK2, MSH2, MSH6, PIK3CA	5.36
34	Li-fraumeni syndrome 1	Enrichment	CHEK2, TP53	5.12
35	Sarcoma	Enrichment	CHEK2, TP53	5.12
36	Breast adenocarcinoma	Enrichment	AKT1, PIK3CA, TP53	5.05
37	Gliosarcoma	Enrichment	ATM, MSH2, TP53	4.96
38	Diffuse large b-cell lymphoma	Enrichment	CHEK2, PTEN, STAT3, TP53	4.92
39	Giant cell glioblastoma	Enrichment	ATM, MSH2, TP53	4.87
40	Capillary malformation-arteriovenous malformation 1	Enrichment	MAP2K1, PIK3CA, RASA1	4.81
41	Hepatocellular carcinoma	Enrichment	CASP8, PIK3CA, RAD50, TP53	4.65
42	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	BCL2, MYC	4.64
43	Dedifferentiated liposarcoma	Enrichment	CDK4, MDM2	4.64
44	Squamous cell carcinoma	Enrichment	RB1, TP53	4.64
45	Adenocarcinoma	Enrichment	ATM, TP53	4.64
46	Well-differentiated liposarcoma	Enrichment	CDK4, MDM2	4.64
47	Hepatoblastoma	Enrichment	BARD1, MSH2, TP53	4.58
48	Cowden syndrome	Enrichment	AKT1, PIK3CA, PTEN	4.44
49	Lipoid congenital adrenal hyperplasia	Enrichment	CYP17A1, HSD3B2	4.35
50	Small cell cancer of the lung	Enrichment	RB1, TP53	4.34
51	Mismatch repair cancer syndrome 1	Enrichment	MSH2, MSH6	4.34
52	Nijmegen breakage syndrome-like disorder	Enrichment	MRE11, RAD50	4.34
53	Leukemia, chronic lymphocytic	Enrichment	ATM, CCND1, TP53	4.28
54	Lymphangioleiomyomatosis	Enrichment	TSC1, TSC2	4.23
55	Hypospadias 1, x-linked	Enrichment	AR, HSD3B2	4.23
56	Lung non-small cell carcinoma	Enrichment	HRAS, MAP2K1, PIK3CA	4.15
57	Glioblastoma	Enrichment	ATM, MSH2	4.12
58	Acute megakaryocytic leukemia	Enrichment	PTEN, TP53	4.12
59	Meningioma	Enrichment	AKT1, PIK3CA, PTEN	4.03
60	Lung cancer	Enrichment	BRCA1, CASP8, CHEK2	4.02
61	Squamous cell carcinoma, head and neck	Enrichment	PTEN, TP53	3.80
62	Tuberous sclerosis 1	Enrichment	TSC1, TSC2	3.75
63	Breast implant-associated anaplastic large cell lymphoma	Enrichment	JAK1, STAT3	3.75
64	Hamartoma	Enrichment	TSC1, TSC2	3.75
65	Autism spectrum disorder	Enrichment	ACTL6B, ARID1B, MAP2K1, PTEN, PTPN11, TSC2	3.70
66	Loeys-dietz syndrome	Enrichment	SMAD2, SMAD3	3.57
67	Melanoma	Enrichment	CHEK2, PTEN	3.47
68	Familial colorectal cancer	Enrichment	MSH2, TP53	3.47
69	Cardiofaciocutaneous syndrome 1	Enrichment	MAP2K1, MAP2K2	3.45
70	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	CRKL, MAPK1	3.45
71	Mantle cell lymphoma	Enrichment	ATM, CCND1	3.45
72	Cardiofaciocutaneous syndrome	Enrichment	MAP2K1, MAP2K2	3.45
73	Tuberous sclerosis	Enrichment	TSC1, TSC2	3.45
74	Noonan syndrome with multiple lentigines	Enrichment	PTPN11, RAF1	3.45
75	Familial colorectal cancer type x	Enrichment	ATM, CHEK2	3.38
76	Myeloma, multiple	Enrichment	ATM, BARD1, TP53	3.29
77	Capillary malformations, congenital	Enrichment	PIK3CA, RASA1	3.23
78	Lymphoma	Enrichment	PTPN11, TP53	3.23
79	Lung cancer susceptibility 3	Enrichment	RB1, TP53	3.17
80	Carboxypeptidase n deficiency	Enrichment	CPN1	3.13
81	Factor xiii, b subunit, deficiency of	Enrichment	F13B	3.13
82	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA, RASA1	3.06
83	Cowden syndrome 1	Enrichment	PIK3CA, PTEN	3.06
84	Hydrops fetalis, nonimmune	Enrichment	ARID1A, HRAS, PTPN11	2.99
85	Nevus, epidermal	Enrichment	HRAS, PIK3CA	2.92
86	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS, PTEN	2.92
87	Renal cell carcinoma, papillary, 1	Enrichment	ATM, MTOR	2.92
88	Gallbladder cancer	Enrichment	PIK3CA, TP53	2.92
89	Follicular thyroid carcinoma	Enrichment	HRAS, PTEN	2.92
90	Adrenal hyperplasia, congenital, due to 3-beta-hydroxysteroid dehydrogenase 2 deficiency	Enrichment	HSD3B2	2.83
91	Cholesteatoma, congenital	Enrichment	F13B	2.83
92	17-beta hydroxysteroid dehydrogenase iii deficiency	Enrichment	HSD17B3	2.83
93	3 beta-hydroxysteroid dehydrogenase deficiency	Enrichment	HSD3B2	2.83
94	Cholesteatoma	Enrichment	F13B	2.83
95	Factor xiii deficiency	Enrichment	F13B	2.83
96	Melanocytic nevus syndrome, congenital	Enrichment	HRAS, RAF1	2.79
97	Ewing sarcoma	Enrichment	ERG, ETV4	2.79
98	Difference of sex development	Enrichment	AR, HSD17B3	2.79
99	Non-immune hydrops fetalis	Enrichment	ARID1A, HRAS, PTPN11	2.76
100	Adrenal hyperplasia, congenital, due to 17-alpha-hydroxylase deficiency	Enrichment	CYP17A1	2.66
101	D-bifunctional protein deficiency	Enrichment	HSD17B4	2.66
102	Palmoplantar keratoderma, punctate type ii	Enrichment	BRCA1	2.55
103	Proteus syndrome	Enrichment	AKT1	2.55
104	Bloom syndrome	Enrichment	BLM	2.55
105	Vacterl association with hydrocephalus	Enrichment	PTEN	2.55
106	Caspase 8 deficiency	Enrichment	CASP8	2.55
107	Melanoma, cutaneous malignant 3	Enrichment	CDK4	2.55
108	Seckel syndrome 1	Enrichment	ATR	2.55
109	Accelerated tumor formation	Enrichment	MDM2	2.55
110	Lessel-kubisch syndrome	Enrichment	MDM2	2.55
111	Bone marrow failure syndrome 5	Enrichment	TP53	2.55
112	Papilloma of choroid plexus	Enrichment	TP53	2.55
113	Basal cell carcinoma 7	Enrichment	TP53	2.55
114	Anaplastic thyroid carcinoma	Enrichment	TP53	2.55
115	Infant-type hemispheric glioma	Enrichment	BRCA1	2.55
116	Papillary tumor of the pineal region	Enrichment	PTEN	2.55
117	Tumor predisposition syndrome 4	Enrichment	CHEK2	2.55
118	Ataxia-telangiectasia-like disorder 1	Enrichment	MRE11	2.55
119	Cutaneous telangiectasia and cancer syndrome, familial	Enrichment	ATR	2.55
120	Immunodeficiency 31a	Enrichment	STAT1	2.55
121	Cowden syndrome 6	Enrichment	AKT1	2.55
122	Loeys-dietz syndrome 6	Enrichment	SMAD2	2.55
123	Endometrial serous adenocarcinoma	Enrichment	ATM	2.55
124	Immunodeficiency 31b	Enrichment	STAT1	2.55
125	Glioma susceptibility 2	Enrichment	PTEN	2.55
126	Ductal carcinoma in situ	Enrichment	TP53	2.55
127	Mismatch repair cancer syndrome 2	Enrichment	MSH2	2.55
128	Leiomyosarcoma	Enrichment	CHEK2	2.55
129	Rectal benign neoplasm	Enrichment	MSH2	2.55
130	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	2.55
131	Trilateral retinoblastoma	Enrichment	RB1	2.55
132	Congenital heart defects, multiple types, 8, with or without heterotaxy	Enrichment	SMAD2	2.55
133	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	2.55
134	Ascending colon cancer	Enrichment	MSH2	2.55
135	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	2.55
136	Oocyte/zygote/embryo maturation arrest 21	Enrichment	CHEK1	2.55
137	B-cell non-hodgkin lymphoma	Enrichment	ATM	2.55
138	Choroid plexus cancer	Enrichment	TP53	2.55
139	Ovarian cyst	Enrichment	MSH2	2.55
140	Pleomorphic xanthoastrocytoma	Enrichment	TP53	2.55
141	Familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome	Enrichment	ATR	2.55
142	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	Enrichment	PTEN	2.55
143	Mendelian susceptibility to mycobacterial diseases due to partial jak1 deficiency	Enrichment	JAK1	2.55
144	Primary peritoneal carcinoma	Enrichment	BRCA1	2.55
145	Lung oat cell carcinoma	Enrichment	RB1	2.55
146	Atrial heart septal defect	Enrichment	ACTL6A, SMARCA4	2.51
147	Interatrial communication	Enrichment	ACTL6A, SMARCA4	2.51
148	Specific learning disability	Enrichment	MAPK1, PTPN11	2.51
149	Pseudohermaphroditism	Enrichment	HSD17B3	2.43
150	Adrenal hyperplasia, congenital, due to 21-hydroxylase deficiency	Enrichment	CYP17A1	2.35
151	21-hydroxylase-deficient congenital adrenal hyperplasia	Enrichment	CYP17A1	2.35
152	Thrombophilia due to thrombin defect	Enrichment	F13B	2.29
153	Burkitt lymphoma	Enrichment	MYC	2.25
154	Muir-torre syndrome	Enrichment	MSH2	2.25
155	Adrenocortical carcinoma, hereditary	Enrichment	TP53	2.25
156	Cervical cancer	Enrichment	TP53	2.25
157	Chromosome 13q14 deletion syndrome	Enrichment	RB1	2.25
158	Lymphoma, hodgkin, classic	Enrichment	TP53	2.25
159	Loeys-dietz syndrome 3	Enrichment	SMAD3	2.25
160	Immunodeficiency 31c	Enrichment	STAT1	2.25
161	Congenital heart defects, multiple types, 3	Enrichment	CHEK2	2.25
162	Fanconi anemia, complementation group s	Enrichment	BRCA1	2.25
163	Cardiac valvular dysplasia, x-linked	Enrichment	ATM	2.25
164	Intravascular large b-cell lymphoma	Enrichment	BCL2	2.25
165	Pancreatic cancer 4	Enrichment	BRCA1	2.25
166	Recessive dystrophic epidermolysis bullosa	Enrichment	MMP1	2.25
167	Congenital fibrosarcoma	Enrichment	TP53	2.25
168	High grade glioma	Enrichment	ATM	2.25
169	Autoinflammation, immune dysregulation, and eosinophilia	Enrichment	JAK1	2.25
170	Cervix carcinoma	Enrichment	TP53	2.25
171	Hodgkin's lymphoma	Enrichment	TP53	2.25
172	T-cell prolymphocytic leukemia	Enrichment	ATM	2.25
173	Inflammatory breast carcinoma	Enrichment	BRCA1	2.25
174	Mismatch repair cancer syndrome 3	Enrichment	MSH6	2.25
175	Peritoneum cancer	Enrichment	BRCA1	2.25
176	Bilateral breast cancer	Enrichment	BRCA1	2.25
177	Vacterl with hydrocephalus	Enrichment	PTEN	2.25
178	Familial retinoblastoma	Enrichment	RB1	2.25
179	Juvenile polyposis of infancy	Enrichment	PTEN	2.25
180	Pleomorphic rhabdomyosarcoma	Enrichment	TP53	2.25
181	Renal cell carcinoma, nonpapillary	Enrichment	ATM, MTOR	2.23
182	Rare genetic intellectual disability	Enrichment	ARID1B, MTOR	2.23
183	Perrault syndrome	Enrichment	HSD17B4	2.23
184	Perrault syndrome 2	Enrichment	HSD17B4	2.18
185	Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay	Enrichment	ARID1A, ARID1B	2.18
186	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	SMAD2, SMAD3	2.17
187	Macrodactyly	Enrichment	PIK3CA	2.11
188	Metachondromatosis	Enrichment	PTPN11	2.11
189	Cystic angiomatosis of bone, diffuse	Enrichment	RASA1	2.11
190	Torticollis	Enrichment	ACTL6A	2.11
191	Prostate cancer, hereditary, x-linked 3	Enrichment	AR	2.11
192	Androgen insensitivity, partial	Enrichment	AR	2.11
193	Deafness, autosomal recessive 26	Enrichment	GAB1	2.11
194	Noonan syndrome 5	Enrichment	RAF1	2.11
195	Noonan syndrome 4	Enrichment	SOS1	2.11
196	Deafness, autosomal recessive 39	Enrichment	HGF	2.11
197	Melorheostosis, isolated	Enrichment	MAP2K1	2.11
198	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.11
199	Leopard syndrome 1	Enrichment	PTPN11	2.11
200	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.11
201	Cowden syndrome 5	Enrichment	PIK3CA	2.11
202	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	2.11
203	Iga nephropathy 3	Enrichment	SPRY2	2.11
204	Intellectual developmental disorder with severe speech and ambulation defects	Enrichment	ACTL6B	2.11
205	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.11
206	Coffin-siris syndrome 11	Enrichment	SMARCD1	2.11
207	Noonan syndrome 13	Enrichment	MAPK1	2.11
208	Hydrocephalus, congenital, 5	Enrichment	SMARCC1	2.11
209	Intellectual developmental disorder with macrocephaly, seizures, and speech delay	Enrichment	PAK1	2.11
210	T-cell large granular lymphocyte leukemia	Enrichment	STAT3	2.11
211	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.11
212	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.11
213	Melorheostosis	Enrichment	MAP2K1	2.11
214	Leopard syndrome 2	Enrichment	RAF1	2.11
215	Immunodeficiency 26 with or without neurologic abnormalities	Enrichment	PRKDC	2.11
216	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	2.11
217	Thrombocytopenia 11 with multiple congenital anomalies and dysmorphic facies	Enrichment	RAP1B	2.11
218	Smarca4-deficient sarcoma of thorax	Enrichment	SMARCA4	2.11
219	Arid1b-related disorder	Enrichment	ARID1B	2.11
220	Ovarian small cell carcinoma	Enrichment	SMARCA4	2.11
221	Autoimmune disease, multisystem, infantile-onset, 1	Enrichment	STAT3	2.11
222	Trigonitis	Enrichment	RAF1	2.11
223	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.11
224	Lymphatic malformation 14	Enrichment	ERG	2.11
225	Hypospadias	Enrichment	PIK3CA	2.11
226	Stat3-related early-onset multisystem autoimmune disease	Enrichment	STAT3	2.11
227	Rare venous malformation	Enrichment	PIK3CA	2.11
228	Gorham's disease	Enrichment	RASA1	2.11
229	Diaphragmatic eventration	Enrichment	PIK3CA	2.11
230	Autosomal recessive severe congenital neutropenia	Enrichment	SMARCD2	2.11
231	Complete androgen insensitivity syndrome	Enrichment	AR	2.11
232	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.11
233	Rare combined vascular malformation	Enrichment	PIK3CA	2.11
234	Cavernous lymphangioma	Enrichment	PIK3CA	2.11
235	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.11
236	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.11
237	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.11
238	Chronic lymphoproliferative disorder of natural killer cells	Enrichment	STAT3	2.11
239	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.11
240	Macrodactyly of toe	Enrichment	PIK3CA	2.11
241	Temporomandibular joint anomaly	Enrichment	DOCK1	2.11
242	Malignant astrocytoma	Enrichment	PTPN11	2.11
243	Epilepsy, myoclonic juvenile	Enrichment	HSD17B3	2.09
244	Retinoblastoma	Enrichment	RB1	2.08
245	Ataxia-telangiectasia	Enrichment	ATM	2.08
246	Polycythemia vera	Enrichment	ATM	2.08
247	Nasopharyngeal carcinoma	Enrichment	TP53	2.08
248	Woolly hair, autosomal recessive 3	Enrichment	RB1	2.08
249	Lynch syndrome 5	Enrichment	MSH6	2.08
250	Hypotrichosis 8	Enrichment	RB1	2.08
251	Koolen-de vries syndrome	Enrichment	ATM	2.08
252	Loeys-dietz syndrome 1	Enrichment	SMAD2	2.08
253	Atypical teratoid rhabdoid tumor	Enrichment	TP53	2.08
254	Anaplastic astrocytoma	Enrichment	TP53	2.08
255	Cellular ependymoma	Enrichment	MSH2	2.08
256	Tanycytic ependymoma	Enrichment	MSH2	2.08
257	Papillary ependymoma	Enrichment	MSH2	2.08
258	T-cell acute lymphoblastic leukemia	Enrichment	BAX	2.08
259	Laryngeal squamous cell carcinoma	Enrichment	PTEN	2.08
260	Intellectual developmental disorder with dysmorphic facies and behavioral abnormalities	Enrichment	MSH6	2.08
261	Colon adenocarcinoma	Enrichment	MSH6	2.08
262	Melanoma of soft tissue	Enrichment	ATF1	2.08
263	Clear cell ependymoma	Enrichment	MSH2	2.08
264	Ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia	Enrichment	MRE11	1.95
265	Gaucher disease, type i	Enrichment	MSH6	1.95
266	Thyroid cancer, nonmedullary, 1	Enrichment	TP53	1.95
267	Polyposis syndrome, hereditary mixed, 1	Enrichment	BRCA1	1.95
268	Cholangiocarcinoma	Enrichment	BRCA1	1.95
269	Lung sarcomatoid carcinoma	Enrichment	TP53	1.95
270	Embryonal rhabdomyosarcoma	Enrichment	TP53	1.95
271	Aortic aneurysm	Enrichment	SMAD3	1.95
272	Hemoglobin c disease	Enrichment	CHEK2	1.95
273	Glioma	Enrichment	PTEN	1.95
274	Benign ependymoma	Enrichment	MSH2	1.95
275	Oculomotor apraxia	Enrichment	ATM	1.95
276	Male infertility due to gonadal dysgenesis or sperm disorder	Enrichment	CHEK1	1.95
277	Perrault syndrome 1	Enrichment	HSD17B4	1.93
278	Rhabdomyosarcoma 2	Enrichment	TP53	1.86
279	Macrocephaly/autism syndrome	Enrichment	PTEN	1.86
280	Breast-ovarian cancer, familial 2	Enrichment	BRCA1	1.86
281	Follicular lymphoma	Enrichment	BCL2	1.86
282	Hemangioma	Enrichment	PTEN	1.86
283	Microcephaly	Enrichment	ARID1A, ARID1B, MAPK1, PTPN11	1.82
284	Fibromatosis, gingival, 1	Enrichment	SOS1	1.81
285	Alopecia, androgenetic, 1	Enrichment	SMARCD1	1.81
286	Costello syndrome	Enrichment	HRAS	1.81
287	Trichomegaly	Enrichment	ARID1B	1.81
288	Specific granule deficiency 1	Enrichment	SMARCD2	1.81
289	Spinal and bulbar muscular atrophy, x-linked 1	Enrichment	AR	1.81
290	Pulmonic stenosis	Enrichment	SOS1	1.81
291	Tropical calcific pancreatitis	Enrichment	SPINK1	1.81
292	Rhabdoid tumor predisposition syndrome 2	Enrichment	SMARCA4	1.81
293	Keratosis, seborrheic	Enrichment	PIK3CA	1.81
294	Chromosome 6q24-q25 deletion syndrome	Enrichment	ARID1B	1.81
295	Noonan syndrome 8	Enrichment	PIK3CA	1.81
296	Charcot-marie-tooth disease, demyelinating, type 4d	Enrichment	NDRG1	1.81
297	Severe combined immunodeficiency with sensitivity to ionizing radiation	Enrichment	ARID1B	1.81
298	Specific granule deficiency 2	Enrichment	SMARCD2	1.81
299	Coffin-siris syndrome 8	Enrichment	SMARCC2	1.81
300	46,xy sex reversal 1	Enrichment	AR	1.81
301	Werner syndrome	Enrichment	PTPN11	1.81
302	Androgen insensitivity syndrome	Enrichment	AR	1.81
303	Cebalid syndrome	Enrichment	MTOR	1.81
304	Rhabdoid tumor predisposition syndrome	Enrichment	SMARCA4	1.81
305	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	1.81
306	Otosclerosis 12	Enrichment	SMARCA4	1.81
307	Coffin-siris syndrome 4	Enrichment	SMARCA4	1.81
308	Smith-kingsmore syndrome	Enrichment	MTOR	1.81
309	Charcot-marie-tooth disease type 4d	Enrichment	NDRG1	1.81
310	Developmental and epileptic encephalopathy 76	Enrichment	ACTL6B	1.81
311	Posterior hypospadias	Enrichment	AR	1.81
312	Tafro syndrome	Enrichment	MAP2K2	1.81
313	Specific granule deficiency	Enrichment	SMARCD2	1.81
314	Wooly hair nevus	Enrichment	HRAS	1.81
315	Wilms tumor 5	Enrichment	CHEK2	1.78
316	Adrenocortical carcinoma	Enrichment	TP53	1.78
317	Clear cell renal cell carcinoma	Enrichment	ATM	1.78
318	Chronic mucocutaneous candidiasis	Enrichment	STAT1	1.78
319	Esophageal cancer	Enrichment	TP53	1.71
320	Essential thrombocythemia	Enrichment	TP53	1.71
321	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	TP53	1.71
322	Severe covid-19	Enrichment	F13B	1.67
323	Glioma susceptibility 1	Enrichment	TP53	1.65
324	Lymphoma, non-hodgkin, familial	Enrichment	TP53	1.65
325	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	STAT3	1.64
326	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.64
327	Polycystic kidney disease, infantile severe, with tuberous sclerosis	Enrichment	TSC2	1.64
328	Nuchal bleb, familial	Enrichment	SOS1	1.64
329	Langerhans cell histiocytosis	Enrichment	MAP2K1	1.64
330	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA	1.64
331	Tuberous sclerosis 2	Enrichment	TSC2	1.64
332	Nail disorder, nonsyndromic congenital, 9	Enrichment	ARID1B	1.64
333	Large congenital melanocytic nevus	Enrichment	HRAS	1.64
334	Coffin-siris syndrome 2	Enrichment	ARID1A	1.64
335	Umbilical hernia	Enrichment	ACTL6A	1.64
336	Hyper ige syndrome	Enrichment	STAT3	1.64
337	Wieacker-wolff syndrome	Enrichment	RASA1	1.64
338	Xanthinuria, type ii	Enrichment	TSC2	1.64
339	Periventricular leukomalacia	Enrichment	ARID1A	1.64
340	Spermatocytoma	Enrichment	HRAS	1.64
341	Tricuspid valve insufficiency	Enrichment	PTPN11	1.64
342	Keratoacanthoma	Enrichment	PIK3CA	1.64
343	Primary hyperaldosteronism	Enrichment	TP53	1.60
344	Familial thoracic aortic aneurysm and dissection	Enrichment	SMAD3	1.60
345	Immune deficiency disease	Enrichment	ATM	1.52
346	Meningioma, familial	Enrichment	PTEN	1.52
347	Myelodysplastic syndrome	Enrichment	TP53	1.52
348	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS	1.51
349	Nicolaides-baraitser syndrome	Enrichment	ARID1B	1.51
350	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	1.51
351	Lipodystrophy, congenital generalized, type 2	Enrichment	ACTL6B	1.51
352	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3CA	1.51
353	Congenital generalized lipodystrophy	Enrichment	FOS	1.51
354	Blepharophimosis	Enrichment	ARID1B	1.51
355	Cerebrovascular disease	Enrichment	PIK3CA	1.51
356	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	PTPN11	1.51
357	Epidermolytic nevus	Enrichment	HRAS	1.51
358	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.51
359	Smarca2-related nicolaides-baraitser syndrome	Enrichment	ARID1B	1.51
360	Gingival fibromatosis	Enrichment	SOS1	1.51
361	Nk-cell enteropathy	Enrichment	CHEK2	1.45
362	Von hippel-lindau syndrome	Enrichment	CCND1	1.42
363	Histiocytoid hemangioma	Enrichment	FOS	1.42
364	Aortic aneurysm, familial thoracic 1	Enrichment	SMAD3	1.41
365	Periventricular nodular heterotopia	Enrichment	BRCA1	1.41
366	Seckel syndrome	Enrichment	ATR	1.41
367	Wilms tumor 1	Enrichment	CHEK2	1.38
368	Primary ovarian insufficiency	Enrichment	CYP17A1	1.37
369	Telangiectasia, hereditary hemorrhagic, type 1	Enrichment	RASA1	1.34
370	Hemihyperplasia, isolated	Enrichment	PIK3CA	1.34
371	Hemangioma, capillary infantile	Enrichment	RASA1	1.34
372	Wiedemann-steiner syndrome	Enrichment	ARID1B	1.34
373	Basal cell carcinoma 1	Enrichment	RASA1	1.34
374	Inguinal hernia	Enrichment	ACTL6A	1.34
375	Keratoconus	Enrichment	TSC1	1.34
376	Patent ductus arteriosus	Enrichment	PTPN11	1.34
377	Lung squamous cell carcinoma	Enrichment	PIK3CA	1.34
378	Hypertrichosis	Enrichment	ARID1B	1.34
379	Melanoma, cutaneous malignant 1	Enrichment	CDK4	1.33
380	Polycystic liver disease	Enrichment	CDC25A	1.33
381	Autosomal dominant polycystic liver disease	Enrichment	CDC25A	1.33
382	Congenital nervous system abnormality	Enrichment	HSD17B4, PTEN, TSC2	1.31
383	Nervous system disease	Enrichment	HSD17B4, PTEN, TSC2	1.31
384	Ehlers-danlos syndrome	Enrichment	SMAD3	1.28
385	Polycystic kidney disease 1 with or without polycystic liver disease	Enrichment	TSC2	1.28
386	Polycystic kidney disease 1	Enrichment	TSC2	1.28
387	Hereditary hemorrhagic telangiectasia	Enrichment	RASA1	1.28
388	Pilomyxoid astrocytoma	Enrichment	RAF1	1.28
389	Congenital hydrocephalus	Enrichment	SMARCC1	1.28
390	Overgrowth syndrome	Enrichment	MTOR	1.28
391	Rare genetic deafness	Enrichment	HSD17B4	1.25
392	Gastroesophageal reflux	Enrichment	ACTL6A	1.22
393	Neuroblastoma	Enrichment	SMARCA4	1.22
394	Permanent neonatal diabetes mellitus	Enrichment	STAT3	1.22
395	Diamond-blackfan anemia 1	Enrichment	TP53	1.20
396	Precursor t-cell acute lymphoblastic leukemia	Enrichment	MYC	1.20
397	Neurofibromatosis, type i	Enrichment	ERG	1.17
398	Ventricular septal defect	Enrichment	SMARCA4	1.17
399	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	AR, PTPN11	1.16
400	Pectus excavatum	Enrichment	PTPN11	1.09
401	46,xy complete gonadal dysgenesis	Enrichment	AR	1.09
402	Diabetes mellitus	Enrichment	SPINK1	1.09
403	Connective tissue disease	Enrichment	SMAD3	1.07
404	Epicanthus	Enrichment	PTPN11	1.05
405	Septooptic dysplasia	Enrichment	ARID1A	1.05
406	Juvenile myelomonocytic leukemia	Enrichment	PTPN11	1.05
407	Congenital long qt syndrome	Enrichment	PTPN11	1.05
408	Fanconi anemia, complementation group a	Enrichment	BRCA1	1.03
409	Aortic valve disease 1	Enrichment	SOS1	1.02
410	Hypercholesterolemia, familial, 1	Enrichment	SMARCA4	1.02
411	Acute promyelocytic leukemia	Enrichment	STAT3	1.02
412	Diamond-blackfan anemia	Enrichment	TP53	1.02
413	Hereditary chronic pancreatitis	Enrichment	SPINK1	0.99
414	46,xy partial gonadal dysgenesis	Enrichment	SOS1	0.99
415	Leukemia, acute myeloid	Enrichment	TP53	0.97
416	Corpus callosum, agenesis of	Enrichment	ARID1B	0.96
417	Familial hypercholesterolemia	Enrichment	SMARCA4	0.96
418	Autosomal dominant polycystic kidney disease	Enrichment	TSC2	0.96
419	Kidney disease	Enrichment	TSC1	0.96
420	Isolated corpus callosum agenesis	Enrichment	ARID1B	0.96
421	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	ARID1B	0.96
422	Pancreatitis, hereditary	Enrichment	SPINK1	0.91
423	Cleft palate, isolated	Enrichment	SMARCA4	0.91
424	Heart, malformation of	Enrichment	MAPK1	0.88
425	Charcot-marie-tooth disease type 4	Enrichment	NDRG1	0.88
426	Patent foramen ovale	Enrichment	PTPN11	0.88
427	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	0.77
428	Scoliosis	Enrichment	PTPN11	0.77
429	Strabismus	Enrichment	PTPN11	0.72
430	Differentiated thyroid carcinoma	Enrichment	HRAS	0.69
431	Long qt syndrome 1	Enrichment	PTPN11	0.68
432	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.65
433	Male infertility	Enrichment	AR	0.63
434	Cakut	Enrichment	ETV4	0.63
435	Left ventricular noncompaction	Enrichment	RAF1	0.62
436	Complex neurodevelopmental disorder	Enrichment	ACTL6A, ACTL6B	0.60
437	Cerebral palsy	Enrichment	SMARCA4	0.58
438	Charcot-marie-tooth disease	Enrichment	NDRG1	0.56
439	Hypertrophic cardiomyopathy	Enrichment	PTPN11	0.55
440	West syndrome	Enrichment	TSC2	0.54
441	Sensorineural hearing loss	Enrichment	HGF	0.51
442	Thrombocytopenia	Enrichment	PTPN11	0.51
443	Hypertelorism	Enrichment	PIK3CA	0.48
444	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	0.47
445	Undetermined early-onset epileptic encephalopathy	Enrichment	ACTL6B	0.45
446	Autism	Enrichment	ACTL6B	0.37
447	Dilated cardiomyopathy	Enrichment	RAF1	0.33
448	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	HGF	0.30

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Androgen receptor network in prostate cancer

Pathway Network for Androgen receptor network in prostate cancer

Pathway network for the Androgen receptor network in prostate cancer SuperPath

Member Pathways for Androgen receptor network in prostate cancer

Pathways in the Androgen receptor network in prostate cancer SuperPath

Gene overlap in member pathways for Androgen receptor network in prostate cancer SuperPath

Associated Genes for Androgen receptor network in prostate cancer

Associated Disorders for Androgen receptor network in prostate cancer

Disorders associated with Androgen receptor network in prostate cancer SuperPath

STRING Interaction Network for Androgen receptor network in prostate cancer

Sources for Androgen receptor network in prostate cancer