Angiogenesis (CST)

No Pathway Network information available for Angiogenesis (CST)

Pathways in the Angiogenesis (CST) SuperPath

#	Name	Source	Genes
1	Angiogenesis	Cell Signaling Technology	ADAMTS1 ANGPT2 ARNT CA9 CCL2 CDH5 CREBBP CRIPTO DLL4 EFNB1 EFNB2 EFNB3 EGLN1 ENG EP300 EPHA2 EPHB1 EPHB2 ETS1 F2RL1 F3 FGF1 FGF2 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 GREM1 HGF HIF1A HIF1AN HMOX1 ITGA5 ITGA6 ITGAV ITGB1 ITGB3 ITGB5 JAG1 KDR MMP13 MMP2 MMP3 MMP7 MMP9 MST1R NDRG1 NDRG2 NDRG3 NDRG4 NEO1 NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 NRP2 PDGFRA PDGFRB PDPN PECAM1 PLN PROX1 PTGS2 PTPN14 RECK REN SERPINB5 SPRY1 TEK TFCP2 TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR3 THBS1 TIMP1 TIMP2 TIMP3 TNC TYMP UNC5B VEGFB VEGFC VWF (see all 89) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ADAMTS1	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 1	Protein Coding	1
2	ANGPT2	Angiopoietin 2	Protein Coding	1
3	ARNT	Aryl Hydrocarbon Receptor Nuclear Translocator	Protein Coding	1
4	CA9	Carbonic Anhydrase 9	Protein Coding	1
5	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	1
6	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	1
7	CDH5	Cadherin 5	Protein Coding	1
8	PTGS2	Prostaglandin-Endoperoxide Synthase 2	Protein Coding	1
9	DLL4	Delta Like Canonical Notch Ligand 4	Protein Coding	1
10	TYMP	Thymidine Phosphorylase	Protein Coding	1
11	EFNB1	Ephrin B1	Protein Coding	1
12	EFNB2	Ephrin B2	Protein Coding	1
13	EFNB3	Ephrin B3	Protein Coding	1
14	EGLN1	Egl-9 Family Hypoxia Inducible Factor 1	Protein Coding	1
15	ENG	Endoglin	Protein Coding	1
16	NOS3	Nitric Oxide Synthase 3	Protein Coding	1
17	EPHA2	EPH Receptor A2	Protein Coding	1
18	EPHB1	EPH Receptor B1	Protein Coding	1
19	EPHB2	EPH Receptor B2	Protein Coding	1
20	ETS1	ETS Proto-Oncogene 1, Transcription Factor	Protein Coding	1
21	F2RL1	F2R Like Trypsin Receptor 1	Protein Coding	1
22	F3	Coagulation Factor III, Tissue Factor	Protein Coding	1
23	FGF1	Fibroblast Growth Factor 1	Protein Coding	1
24	FGF2	Fibroblast Growth Factor 2	Protein Coding	1
25	FGFR1	Fibroblast Growth Factor Receptor 1	Protein Coding	1
26	FGFR2	Fibroblast Growth Factor Receptor 2	Protein Coding	1
27	FGFR3	Fibroblast Growth Factor Receptor 3	Protein Coding	1
28	FGFR4	Fibroblast Growth Factor Receptor 4	Protein Coding	1
29	GREM1	Gremlin 1, DAN Family BMP Antagonist	Protein Coding	1
30	HGF	Hepatocyte Growth Factor	Protein Coding	1
31	HIF1A	Hypoxia Inducible Factor 1 Subunit Alpha	Protein Coding	1
32	HIF1AN	Hypoxia Inducible Factor 1 Subunit Alpha Inhibitor	Protein Coding	1
33	HMOX1	Heme Oxygenase 1	Protein Coding	1
34	ITGA5	Integrin Subunit Alpha 5	Protein Coding	1
35	ITGA6	Integrin Subunit Alpha 6	Protein Coding	1
36	ITGAV	Integrin Subunit Alpha V	Protein Coding	1
37	ITGB1	Integrin Subunit Beta 1	Protein Coding	1
38	ITGB3	Integrin Subunit Beta 3	Protein Coding	1
39	ITGB5	Integrin Subunit Beta 5	Protein Coding	1
40	JAG1	Jagged Canonical Notch Ligand 1	Protein Coding	1
41	SERPINB5	Serpin Family B Member 5	Protein Coding	1
42	MMP13	Matrix Metallopeptidase 13	Protein Coding	1
43	MMP2	Matrix Metallopeptidase 2	Protein Coding	1
44	MMP3	Matrix Metallopeptidase 3	Protein Coding	1
45	MMP7	Matrix Metallopeptidase 7	Protein Coding	1
46	MMP9	Matrix Metallopeptidase 9	Protein Coding	1
47	NDRG1	N-Myc Downstream Regulated 1	Protein Coding	1
48	NDRG2	NDRG Family Member 2	Protein Coding	1
49	NDRG3	NDRG Family Member 3	Protein Coding	1
50	NDRG4	NDRG Family Member 4	Protein Coding	1
51	NEO1	Neogenin 1	Protein Coding	1
52	NOTCH1	Notch Receptor 1	Protein Coding	1
53	NOTCH2	Notch Receptor 2	Protein Coding	1
54	NOTCH3	Notch Receptor 3	Protein Coding	1
55	NOTCH4	Notch Receptor 4	Protein Coding	1
56	NRP2	Neuropilin 2	Protein Coding	1
57	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
58	PDGFRA	Platelet Derived Growth Factor Receptor Alpha	Protein Coding	1
59	PDGFRB	Platelet Derived Growth Factor Receptor Beta	Protein Coding	1
60	PDPN	Podoplanin	Protein Coding	1
61	PECAM1	Platelet And Endothelial Cell Adhesion Molecule 1	Protein Coding	1
62	PLN	Phospholamban	Protein Coding	1
63	PROX1	Prospero Homeobox 1	Protein Coding	1
64	PTPN14	Protein Tyrosine Phosphatase Non-Receptor Type 14	Protein Coding	1
65	RECK	Reversion Inducing Cysteine Rich Protein With Kazal Motifs	Protein Coding	1
66	REN	Renin	Protein Coding	1
67	MST1R	Macrophage Stimulating 1 Receptor	Protein Coding	1
68	SPRY1	Sprouty RTK Signaling Antagonist 1	Protein Coding	1
69	CRIPTO	Cripto, EGF-CFC Family Member	Protein Coding	1
70	TFCP2	Transcription Factor CP2	Protein Coding	1
71	TGFA	Transforming Growth Factor Alpha	Protein Coding	1
72	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1
73	TGFB2	Transforming Growth Factor Beta 2	Protein Coding	1
74	TGFB3	Transforming Growth Factor Beta 3	Protein Coding	1
75	TGFBR1	Transforming Growth Factor Beta Receptor 1	Protein Coding	1
76	TGFBR3	Transforming Growth Factor Beta Receptor 3	Protein Coding	1
77	THBS1	Thrombospondin 1	Protein Coding	1
78	TEK	TEK Receptor Tyrosine Kinase	Protein Coding	1
79	TIMP1	TIMP Metallopeptidase Inhibitor 1	Protein Coding	1
80	TIMP2	TIMP Metallopeptidase Inhibitor 2	Protein Coding	1
81	TIMP3	TIMP Metallopeptidase Inhibitor 3	Protein Coding	1
82	TNC	Tenascin C	Protein Coding	1
83	UNC5B	Unc-5 Netrin Receptor B	Protein Coding	1
84	VEGFB	Vascular Endothelial Growth Factor B	Protein Coding	1
85	VEGFC	Vascular Endothelial Growth Factor C	Protein Coding	1
86	FLT1	Fms Related Receptor Tyrosine Kinase 1	Protein Coding	1
87	KDR	Kinase Insert Domain Receptor	Protein Coding	1
88	FLT4	Fms Related Receptor Tyrosine Kinase 4	Protein Coding	1
89	VWF	Von Willebrand Factor	Protein Coding	1

Disorders associated with Angiogenesis (CST) SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Hemifacial hyperplasia	Enrichment	EFNB1, FGFR2, FGFR3	5.57
2	Primary hypereosinophilic syndrome	Enrichment	FGFR1, PDGFRA, PDGFRB	5.57
3	Loeys-dietz syndrome	Enrichment	TGFB2, TGFB3, TGFBR1	4.65
4	Tetralogy of fallot	Enrichment	FLT4, JAG1, KDR, NOTCH1	4.63
5	Primary ovarian insufficiency	Enrichment	ADAMTS1, KDR, NOS3, NOTCH2, THBS1	4.39
6	Pfeiffer syndrome	Enrichment	FGFR1, FGFR2	4.37
7	Jackson-weiss syndrome	Enrichment	FGFR1, FGFR2	4.37
8	Infantile myofibromatosis	Enrichment	NOTCH3, PDGFRB	4.37
9	Loeys-dietz syndrome 4	Enrichment	TGFB2, TGFB3	4.37
10	Metaphyseal anadysplasia	Enrichment	MMP13, MMP9	4.37
11	Crouzon syndrome	Enrichment	FGFR2, FGFR3	3.90
12	Lacrimoauriculodentodigital syndrome 1	Enrichment	FGFR2, FGFR3	3.90
13	Keratoacanthoma	Enrichment	NOTCH1, NOTCH2	3.90
14	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	NOTCH1, TGFB2, TGFB3, TGFBR1	3.72
15	Saethre-chotzen syndrome	Enrichment	FGFR2, FGFR3	3.60
16	Hepatoblastoma	Enrichment	FGFR3, JAG1, REN	3.48
17	Pre-eclampsia	Enrichment	FLT1, NOS3	3.38
18	Familial cerebral saccular aneurysm	Enrichment	ENG, TGFBR3	3.38
19	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	3.20
20	Hemangioma, capillary infantile	Enrichment	FLT4, KDR	3.20
21	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	3.20
22	Adams-oliver syndrome	Enrichment	DLL4, NOTCH1	3.06
23	Marfan syndrome	Enrichment	TGFB2, TGFBR1	2.73
24	Stroke, ischemic	Enrichment	NOS3, NOTCH3	2.73
25	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	PLN, TGFB3	2.43
26	Hydrocephalus	Enrichment	FGFR2, PDGFRB	2.37
27	Rare genetic intellectual disability	Enrichment	CREBBP, EP300	2.37
28	Gliosarcoma	Enrichment	FGFR1, FGFR3	2.32
29	Microform holoprosencephaly	Enrichment	CRIPTO, FGFR1	2.32
30	Lobar holoprosencephaly	Enrichment	CRIPTO, FGFR1	2.32
31	Giant cell glioblastoma	Enrichment	FGFR1, FGFR3	2.27
32	Myeloma, multiple	Enrichment	CREBBP, FGFR3, MST1R	2.23
33	Semilobar holoprosencephaly	Enrichment	CRIPTO, FGFR1	2.22
34	Hypochondroplasia	Enrichment	FGFR3	2.18
35	Beare-stevenson cutis gyrata syndrome	Enrichment	FGFR2	2.18
36	Osteoglophonic dysplasia	Enrichment	FGFR1	2.18
37	Thanatophoric dysplasia, type i	Enrichment	FGFR3	2.18
38	Trigonocephaly 1	Enrichment	FGFR1	2.18
39	Von willebrand disease, type 1	Enrichment	VWF	2.18
40	Muenke syndrome	Enrichment	FGFR3	2.18
41	Premature aging syndrome, penttinen type	Enrichment	PDGFRB	2.18
42	Hypereosinophilic syndrome, idiopathic	Enrichment	PDGFRA	2.18
43	Deafness, autosomal recessive 39	Enrichment	HGF	2.18
44	Scaphocephaly, maxillary retrusion, and impaired intellectual development	Enrichment	FGFR2	2.18
45	Apert syndrome	Enrichment	FGFR2	2.18
46	Hajdu-cheney syndrome	Enrichment	NOTCH2	2.18
47	Alagille syndrome 2	Enrichment	NOTCH2	2.18
48	Lateral meningocele syndrome	Enrichment	NOTCH3	2.18
49	Multiple self-healing squamous epithelioma	Enrichment	TGFBR1	2.18
50	Von willebrand disease, type 2	Enrichment	VWF	2.18
51	Myofibromatosis, infantile, 1	Enrichment	PDGFRB	2.18
52	Thanatophoric dysplasia, type ii	Enrichment	FGFR3	2.18
53	Deafness, autosomal dominant 56	Enrichment	TNC	2.18
54	Gist-plus syndrome	Enrichment	PDGFRA	2.18
55	Camptodactyly, tall stature, and hearing loss syndrome	Enrichment	FGFR3	2.18
56	Bent bone dysplasia syndrome 1	Enrichment	FGFR2	2.18
57	Charcot-marie-tooth disease, axonal, type 2hh	Enrichment	JAG1	2.18
58	Adams-oliver syndrome 6	Enrichment	DLL4	2.18
59	Venous malformations, multiple cutaneous and mucosal	Enrichment	TEK	2.18
60	Von willebrand disease, type 3	Enrichment	VWF	2.18
61	Craniofrontonasal syndrome	Enrichment	EFNB1	2.18
62	Hereditary lymphedema id	Enrichment	VEGFC	2.18
63	Hemoglobin, high altitude adaptation	Enrichment	EGLN1	2.18
64	Myeloid and lymphoid neoplasms associated with pdgfra rearrangement	Enrichment	PDGFRA	2.18
65	Lymphatic malformation 4	Enrichment	VEGFC	2.18
66	Prostate cancer/brain cancer susceptibility	Enrichment	EPHB2	2.18
67	Crouzon syndrome with acanthosis nigricans	Enrichment	FGFR3	2.18
68	Camurati-engelmann disease 2	Enrichment	TGFB2	2.18
69	Coronary heart disease 6	Enrichment	MMP3	2.18
70	Basal ganglia calcification, idiopathic, 4	Enrichment	PDGFRB	2.18
71	Myofibromatosis, infantile, 2	Enrichment	NOTCH3	2.18
72	Nasopharyngeal carcinoma 3	Enrichment	MST1R	2.18
73	Myeloid and lymphoid neoplasms associated with pdgfrb rearrangement	Enrichment	PDGFRB	2.18
74	Choanal atresia and lymphedema	Enrichment	PTPN14	2.18
75	Achondroplasia, severe, with developmental delay and acanthosis nigricans	Enrichment	FGFR3	2.18
76	Kosaki overgrowth syndrome	Enrichment	PDGFRB	2.18
77	Heme oxygenase 1 deficiency	Enrichment	HMOX1	2.18
78	Hartsfield syndrome	Enrichment	FGFR1	2.18
79	Congenital heart defects, multiple types, 7	Enrichment	FLT4	2.18
80	Loeys-dietz syndrome 5	Enrichment	TGFB3	2.18
81	Bleeding disorder, platelet-type, 22	Enrichment	EPHB2	2.18
82	Glaucoma 3, primary congenital, e	Enrichment	TEK	2.18
83	Deafness, congenital heart defects, and posterior embryotoxon	Enrichment	JAG1	2.18
84	Von willebrand's disease	Enrichment	VWF	2.18
85	Menke-hennekam syndrome 1	Enrichment	CREBBP	2.18
86	Ocular pterygium-digital keloid dysplasia syndrome	Enrichment	PDGFRB	2.18
87	Tufted angioma of skin	Enrichment	KDR	2.18
88	Lacrimoauriculodentodigital syndrome 2	Enrichment	FGFR3	2.18
89	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	2.18
90	Bockenheimer syndrome	Enrichment	TEK	2.18
91	Transient cerebral ischemia	Enrichment	NOTCH3	2.18
92	Cerebral arteriopathy, autosomal recessive, with subcortical infarcts and leukoencephalopathy 1	Enrichment	NOTCH3	2.18
93	Immune dysregulation, neurodevelopmental defects, and colitis	Enrichment	ITGAV	2.18
94	Fgfr3-related chondrodysplasia	Enrichment	FGFR3	2.18
95	Congenital primary lymphedema of gordon	Enrichment	VEGFC	2.18
96	Camptodactyly-tall stature-scoliosis-hearing loss syndrome	Enrichment	FGFR3	2.18
97	Menke-hennekam syndrome	Enrichment	CREBBP	2.18
98	Lymphedema-posterior choanal atresia syndrome	Enrichment	PTPN14	2.18
99	Hartsfield-bixler-demyer syndrome	Enrichment	FGFR1	2.18
100	Non-syndromic unicoronal craniosynostosis	Enrichment	FGFR2	2.18
101	Arteriovenous malformations of the brain	Enrichment	ENG, TIMP3	2.17
102	Craniosynostosis	Enrichment	FGFR2, FGFR3	2.13
103	Tooth agenesis	Enrichment	FGFR1, TGFA	2.04
104	Lymphatic malformation 1	Enrichment	FLT4	1.88
105	Blue rubber bleb nevus	Enrichment	TEK	1.88
106	Sorsby fundus dystrophy	Enrichment	TIMP3	1.88
107	Myeloproliferative disorder, chronic, with eosinophilia	Enrichment	PDGFRB	1.88
108	Camurati-engelmann disease 1	Enrichment	TGFB1	1.88
109	Metaphyseal dysplasia, spahr type	Enrichment	MMP13	1.88
110	Thumb deformity	Enrichment	CREBBP	1.88
111	Intracranial hypertension, idiopathic	Enrichment	FLT4	1.88
112	Spondyloepimetaphyseal dysplasia, missouri type	Enrichment	MMP13	1.88
113	Cervical cancer	Enrichment	FGFR3	1.88
114	Pulmonary arteriovenous fistulas	Enrichment	ENG	1.88
115	Loeys-dietz syndrome 2	Enrichment	TGFBR1	1.88
116	Tubulointerstitial kidney disease, autosomal dominant 4	Enrichment	REN	1.88
117	Aural atresia, congenital	Enrichment	FGFR2	1.88
118	Cardiomyopathy, dilated, 1p	Enrichment	PLN	1.88
119	Keratosis, seborrheic	Enrichment	FGFR3	1.88
120	Encephalocraniocutaneous lipomatosis	Enrichment	FGFR1	1.88
121	Adams-oliver syndrome 5	Enrichment	NOTCH1	1.88
122	Angioma, tufted	Enrichment	KDR	1.88
123	Cardiomyopathy, familial hypertrophic, 18	Enrichment	PLN	1.88
124	Antley-bixler syndrome without genital anomalies or disordered steroidogenesis	Enrichment	FGFR2	1.88
125	Charcot-marie-tooth disease, demyelinating, type 4d	Enrichment	NDRG1	1.88
126	Menke-hennekam syndrome 2	Enrichment	EP300	1.88
127	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.88
128	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	1.88
129	Split hand-foot malformation	Enrichment	FGFR2	1.88
130	Rosette-forming glioneuronal tumor	Enrichment	FGFR1	1.88
131	Lipodystrophy, familial partial, type 1	Enrichment	NOTCH3	1.88
132	Erythrocytosis, familial, 3	Enrichment	EGLN1	1.88
133	Depressive disorder	Enrichment	NOTCH3	1.88
134	Camurati-engelmann disease	Enrichment	TGFB1	1.88
135	Metaphyseal anadysplasia 2	Enrichment	MMP9	1.88
136	Cervix carcinoma	Enrichment	FGFR3	1.88
137	Hereditary lymphedema i	Enrichment	FLT4	1.88
138	Hereditary mixed polyposis syndrome	Enrichment	GREM1	1.88
139	Lymphatic malformation 10	Enrichment	ANGPT2	1.88
140	Interfrontal craniofaciosynostosis	Enrichment	FGFR1	1.88
141	Charcot-marie-tooth disease type 4d	Enrichment	NDRG1	1.88
142	Autosomal dominant nonsyndromic deafness	Enrichment	FGFR2	1.88
143	Chronic eosinophilic leukemia	Enrichment	PDGFRA	1.88
144	B-lymphoblastic leukemia/lymphoma with recurrent genetic abnormality	Enrichment	PDGFRA	1.88
145	Non-immune hydrops fetalis	Enrichment	ANGPT2, FLT4	1.76
146	Cystic fibrosis	Enrichment	HMOX1, TGFB1	1.73
147	Connective tissue disease	Enrichment	FGFR3, NOTCH1	1.73
148	Colorectal cancer	Enrichment	EP300, FGFR2, FGFR3	1.71
149	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	ITGB3	1.71
150	Achondroplasia	Enrichment	FGFR3	1.71
151	Jacobsen syndrome	Enrichment	ETS1	1.71
152	Hypogonadotropic hypogonadism 2 with or without anosmia	Enrichment	FGFR1	1.71
153	Larsen syndrome	Enrichment	FGFR3	1.71
154	Alagille syndrome 1	Enrichment	JAG1	1.71
155	Bleeding disorder, platelet-type, 16	Enrichment	ITGB3	1.71
156	Periventricular nodular heterotopia 1	Enrichment	VWF	1.71
157	Multicentric osteolysis, nodulosis, and arthropathy	Enrichment	MMP2	1.71
158	Chromosome 8p11 myeloproliferative syndrome	Enrichment	FGFR1	1.71
159	Epidermolysis bullosa, junctional 6, with pyloric atresia	Enrichment	ITGA6	1.71
160	Tethered spinal cord syndrome	Enrichment	CREBBP	1.71
161	Intrinsic cardiomyopathy	Enrichment	PLN	1.71
162	Loeys-dietz syndrome 1	Enrichment	TGFBR1	1.71
163	Hamartoma	Enrichment	FGFR3	1.71
164	Testicular germ cell cancer	Enrichment	FGFR3	1.71
165	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	1.71
166	Migraine without aura	Enrichment	NOTCH3	1.71
167	Spermatocytoma	Enrichment	FGFR3	1.71
168	Bleeding disorder, platelet-type, 24	Enrichment	ITGB3	1.71
169	Enchondromatosis	Enrichment	HIF1A	1.71
170	Testicular cancer	Enrichment	FGFR3	1.71
171	Polyposis syndrome, hereditary mixed, 1	Enrichment	GREM1	1.59
172	Glaucoma 3, primary infantile, b	Enrichment	TEK	1.59
173	Cerebrovascular disease	Enrichment	NOTCH3	1.59
174	Aortic aneurysm	Enrichment	TGFBR1	1.59
175	Non-syndromic bicoronal craniosynostosis	Enrichment	FGFR3	1.59
176	Glioma	Enrichment	FGFR2	1.59
177	Middle aortic syndrome	Enrichment	JAG1	1.59
178	Systemic lupus erythematosus	Enrichment	ENG, ETS1	1.57
179	Cataract 6, multiple types	Enrichment	EPHA2	1.49
180	Enchondromatosis, multiple, ollier type	Enrichment	HIF1A	1.49
181	Alzheimer disease 2	Enrichment	NOS3	1.49
182	Arrhythmogenic right ventricular dysplasia, familial, 1	Enrichment	TGFB3	1.49
183	Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1	Enrichment	NOTCH3	1.49
184	Microcephaly 1, primary, autosomal recessive	Enrichment	ANGPT2	1.49
185	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.49
186	Glanzmann thrombasthenia 2	Enrichment	ITGB3	1.49
187	Cardiac arrest	Enrichment	PLN	1.49
188	Holoprosencephaly	Enrichment	FGFR1	1.49
189	Epidermolysis bullosa	Enrichment	ITGA6	1.49
190	Arrhythmogenic right ventricular dysplasia 1	Enrichment	TGFB3	1.49
191	Aplasia cutis congenita	Enrichment	DLL4	1.49
192	Vascular dementia	Enrichment	NOTCH3	1.49
193	Aniridia	Enrichment	EPHA2	1.49
194	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	ENG	1.49
195	Atrial septal defect 1	Enrichment	TGFB2	1.41
196	Telangiectasia, hereditary hemorrhagic, type 1	Enrichment	ENG	1.41
197	Split-hand/foot malformation 1	Enrichment	FGFR2	1.41
198	Holoprosencephaly 1	Enrichment	FGFR1	1.41
199	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	ITGA6	1.41
200	Testicular germ cell tumor	Enrichment	FGFR3	1.41
201	Renal tubular dysgenesis	Enrichment	REN	1.41
202	Mitochondrial dna depletion syndrome 1	Enrichment	TYMP	1.41
203	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	1.41
204	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	ITGB3	1.41
205	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	1.41
206	Lung squamous cell carcinoma	Enrichment	FGFR3	1.41
207	Hypertrichosis	Enrichment	CREBBP	1.41
208	Classic ehlers-danlos syndrome	Enrichment	TGFBR1	1.41
209	46,xy disorder of sex development	Enrichment	FGFR3	1.41
210	Autosomal dominant secondary polycythemia	Enrichment	EGLN1	1.41
211	Thrombocytopenia	Enrichment	ITGB3, VWF	1.40
212	Nevus, epidermal	Enrichment	FGFR3	1.35
213	Glaucoma 3, primary congenital, a	Enrichment	TEK	1.35
214	Glanzmann thrombasthenia 1	Enrichment	ITGB3	1.35
215	Gastrointestinal stromal tumor	Enrichment	PDGFRA	1.35
216	Multiple enchondromatosis, maffucci type	Enrichment	HIF1A	1.35
217	Hereditary hemorrhagic telangiectasia	Enrichment	ENG	1.35
218	Pilomyxoid astrocytoma	Enrichment	FGFR1	1.35
219	Hypertelorism	Enrichment	EFNB1, FGFR2	1.34
220	Basal ganglia calcification, idiopathic, 1	Enrichment	PDGFRB	1.29
221	Mitochondrial dna depletion syndrome 4b	Enrichment	TYMP	1.29
222	Hypoplastic left heart syndrome	Enrichment	NOTCH1	1.29
223	Early-onset posterior polar cataract	Enrichment	EPHA2	1.29
224	Charge syndrome	Enrichment	EP300	1.24
225	Arrhythmogenic right ventricular dysplasia, familial, 9	Enrichment	PLN	1.24
226	Arteriovenous malformation	Enrichment	TEK	1.24
227	Hypogonadotropic hypogonadism	Enrichment	FGFR1	1.24
228	Junctional epidermolysis bullosa	Enrichment	ITGA6	1.24
229	Ventricular septal defect	Enrichment	TEK	1.24
230	Mitochondrial neurogastrointestinal encephalomyopathy	Enrichment	TYMP	1.24
231	Meier-gorlin syndrome 1	Enrichment	FGFR2	1.20
232	Myopathy, x-linked, with excessive autophagy	Enrichment	TEK	1.20
233	Autosomal dominant macrothrombocytopenia	Enrichment	ITGB3	1.20
234	Familial colorectal cancer	Enrichment	GREM1	1.20
235	Primary bone dysplasia	Enrichment	FGFR3	1.20
236	Migraine with or without aura 1	Enrichment	NOTCH3	1.16
237	Pectus excavatum	Enrichment	TGFBR1	1.16
238	Osteochondrodysplasia	Enrichment	FGFR3	1.16
239	Heritable pulmonary arterial hypertension	Enrichment	ENG	1.16
240	Cardiac conduction defect	Enrichment	PLN	1.12
241	Septooptic dysplasia	Enrichment	FGFR1	1.12
242	Renal hypodysplasia/aplasia 3	Enrichment	FGFR3	1.12
243	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	TGFB3	1.12
244	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	TGFB3	1.12
245	Aortic valve disease 1	Enrichment	NOTCH1	1.09
246	Neural tube defects	Enrichment	ITGB1	1.09
247	Pulmonary hypertension, primary, 1	Enrichment	ENG	1.09
248	Pulmonary disease, chronic obstructive	Enrichment	HMOX1	1.09
249	Chromosome 1p36 deletion syndrome	Enrichment	PDPN	1.09
250	Hypogonadotropic hypogonadism 7 with or without anosmia	Enrichment	FGFR1	1.06
251	Aortic aneurysm, familial thoracic 1	Enrichment	NOTCH1	1.06
252	Heart disease	Enrichment	CREBBP	1.06
253	Cataract	Enrichment	EPHA2	1.06
254	Cleft lip/palate	Enrichment	PDGFRA	1.06
255	Polydactyly, postaxial, type a1	Enrichment	EP300	1.03
256	Corpus callosum, agenesis of	Enrichment	CREBBP	1.03
257	Isolated corpus callosum agenesis	Enrichment	CREBBP	1.03
258	Septopreoptic holoprosencephaly	Enrichment	CRIPTO	1.03
259	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP	1.03
260	Midline interhemispheric variant of holoprosencephaly	Enrichment	CRIPTO	1.03
261	Alzheimer disease, familial, 1	Enrichment	NOS3	0.97
262	Hypertension, essential	Enrichment	NOS3	0.97
263	Dandy-walker syndrome	Enrichment	PDGFRB	0.97
264	Sudden infant death syndrome	Enrichment	PLN	0.97
265	Cataract 44	Enrichment	EPHA2	0.97
266	Alobar holoprosencephaly	Enrichment	CRIPTO	0.97
267	Heart, malformation of	Enrichment	JAG1	0.95
268	Human immunodeficiency virus type 1	Enrichment	CCL2	0.95
269	Charcot-marie-tooth disease type 4	Enrichment	NDRG1	0.95
270	Normosmic congenital hypogonadotropic hypogonadism	Enrichment	FGFR1	0.95
271	Early-onset nuclear cataract	Enrichment	EPHA2	0.95
272	Diffuse large b-cell lymphoma	Enrichment	CREBBP	0.93
273	Ehlers-danlos syndrome	Enrichment	TGFB2	0.93
274	Endometrial cancer	Enrichment	FGFR2	0.89
275	Myocardial infarction	Enrichment	ITGB3	0.87
276	Kallmann syndrome	Enrichment	FGFR1	0.85
277	Scoliosis	Enrichment	CREBBP	0.83
278	Congenital nervous system abnormality	Enrichment	CREBBP, FGFR3	0.81
279	Nervous system disease	Enrichment	CREBBP, FGFR3	0.81
280	Hydrops fetalis, nonimmune	Enrichment	FLT4	0.80
281	Auditory neuropathy	Enrichment	NOTCH3	0.80
282	Bladder cancer	Enrichment	FGFR3	0.76
283	Prostate cancer	Enrichment	EPHB2	0.76
284	Severe covid-19	Enrichment	ITGAV	0.76
285	Primary autosomal recessive microcephaly	Enrichment	ANGPT2	0.72
286	Cerebral palsy	Enrichment	PDGFRB	0.64
287	Charcot-marie-tooth disease	Enrichment	NDRG1	0.63
288	Gastric cancer	Enrichment	FGFR2	0.61
289	Hypertrophic cardiomyopathy	Enrichment	PLN	0.61
290	Sensorineural hearing loss	Enrichment	HGF	0.57
291	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	TNC	0.54
292	Familial isolated dilated cardiomyopathy	Enrichment	PLN	0.53
293	Autism	Enrichment	CREBBP	0.42
294	Dilated cardiomyopathy	Enrichment	PLN	0.39
295	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	HGF	0.35
296	Ovarian cancer	Enrichment	PDGFRA	0.31
297	Microcephaly	Enrichment	EP300	0.25
298	Hereditary retinal dystrophy	Enrichment	JAG1, TIMP3	0.24
299	Fundus dystrophy	Enrichment	JAG1, TIMP3	0.24
300	Inherited cancer-predisposing syndrome	Enrichment	PDGFRA	0.23

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Angiogenesis (CST)

Pathway Network for Angiogenesis (CST)

Member Pathways for Angiogenesis (CST)

Pathways in the Angiogenesis (CST) SuperPath

Associated Genes for Angiogenesis (CST)

Associated Disorders for Angiogenesis (CST)

Disorders associated with Angiogenesis (CST) SuperPath

STRING Interaction Network for Angiogenesis (CST)

Sources for Angiogenesis (CST)