Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics

No Pathway Network information available for Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics

Pathways in the Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics SuperPath

#	Name	Source	Genes
1	Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics	PharmGKB	AGRP ANKK1 CARTPT DRD2 GHRL GHSR HTR2C INS INSIG2 LEP LEPR MC4R NPY NPY1R NPY2R POMC PRL PYY SNAP25 TH (see all 20) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PYY	Peptide YY	Protein Coding	1
2	TH	Tyrosine Hydroxylase	Protein Coding	1
3	AGRP	Agouti Related Neuropeptide	Protein Coding	1
4	DRD2	Dopamine Receptor D2	Protein Coding	1
5	SNAP25	Synaptosome Associated Protein 25	Protein Coding	1
6	MC4R	Melanocortin 4 Receptor	Protein Coding	1
7	POMC	Proopiomelanocortin	Protein Coding	1
8	INS	Insulin	Protein Coding	1
9	NPY	Neuropeptide Y	Protein Coding	1
10	NPY1R	Neuropeptide Y Receptor Y1	Protein Coding	1
11	NPY2R	Neuropeptide Y Receptor Y2	Protein Coding	1
12	HTR2C	5-Hydroxytryptamine Receptor 2C	Protein Coding	1
13	PRL	Prolactin	Protein Coding	1
14	LEP	Leptin	Protein Coding	1
15	LEPR	Leptin Receptor	Protein Coding	1
16	GHSR	Growth Hormone Secretagogue Receptor	Protein Coding	1
17	ANKK1	Ankyrin Repeat And Kinase Domain Containing 1	Protein Coding	1
18	INSIG2	Insulin Induced Gene 2	Protein Coding	1
19	GHRL	Ghrelin And Obestatin Prepropeptide	Protein Coding	1
20	CARTPT	CART Prepropeptide	Protein Coding	1

Disorders associated with Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Body mass index quantitative trait locus 11	Enrichment	AGRP, CARTPT, GHRL, LEPR, MC4R, POMC	10.09
2	Leptin deficiency or dysfunction	Enrichment	LEP, LEPR	4.91
3	Developmental and epileptic encephalopathy 117	Enrichment	SNAP25	2.83
4	Body mass index quantitative trait locus 20	Enrichment	MC4R	2.83
5	Epilepsy with generalized tonic-clonic seizures	Enrichment	SNAP25	2.83
6	Leptin receptor deficiency	Enrichment	LEPR	2.83
7	Obesity due to melanocortin 4 receptor deficiency	Enrichment	MC4R	2.83
8	Short stature due to growth hormone secretagogue receptor deficiency	Enrichment	GHSR	2.83
9	N-acetylglutamate synthase deficiency	Enrichment	PYY	2.53
10	Segawa syndrome, autosomal recessive	Enrichment	TH	2.53
11	Growth hormone deficiency, isolated partial	Enrichment	GHSR	2.53
12	Maturity-onset diabetes of the young, type 10	Enrichment	INS	2.53
13	Hyperproinsulinemia	Enrichment	INS	2.53
14	Diabetes mellitus, permanent neonatal, 4	Enrichment	INS	2.53
15	Type 1 diabetes mellitus 2	Enrichment	INS	2.35
16	Dystonia, dopa-responsive	Enrichment	TH	2.35
17	Obesity, early-onset, with adrenal insufficiency and red hair	Enrichment	POMC	2.35
18	Obesity due to pro-opiomelanocortin deficiency	Enrichment	POMC	2.35
19	Developmental and epileptic encephalopathy 2	Enrichment	SNAP25	2.23
20	Neonatal diabetes mellitus	Enrichment	INS	2.23
21	Dystonia 11, myoclonic	Enrichment	DRD2	2.05
22	Type 1 diabetes mellitus	Enrichment	INS	2.05
23	Focal epilepsy	Enrichment	SNAP25	1.99
24	Permanent neonatal diabetes mellitus	Enrichment	INS	1.93
25	Diabetes mellitus	Enrichment	INS	1.79
26	Presynaptic congenital myasthenic syndromes	Enrichment	SNAP25	1.79
27	Stereotypic movement disorder	Enrichment	SNAP25	1.72
28	Maturity-onset diabetes of the young	Enrichment	INS	1.54
29	Dystonia	Enrichment	TH	1.30
30	Developmental and epileptic encephalopathy	Enrichment	SNAP25	1.29
31	Optic atrophy plus syndrome	Enrichment	SNAP25	1.20
32	Microcephaly	Enrichment	SNAP25	0.78

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics

Pathway Network for Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics

Member Pathways for Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics

Pathways in the Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics SuperPath

Associated Genes for Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics

Associated Disorders for Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics

Disorders associated with Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics SuperPath

STRING Interaction Network for Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics

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