AP-1 transcription factor network

No Pathway Network information available for AP-1 transcription factor network

Pathways in the AP-1 transcription factor network SuperPath

#	Name	Source	Genes
1	AP-1 transcription factor network	PubChem	ACTA1 AGT ATF2 ATF3 BAG1 BCL2L11 CBFB CCL2 CCN1 CCND1 CDK1 CDKN1B CDKN2A COL1A2 COPS5 CREB1 CRTC1 CSF2 CTNNB1 CXCL8 DMP1 DMTF1 DUSP1 EDN1 EGR1 ELF1 EP300 ESR1 ETS1 FABP4 FOS FOSB FOSL1 FOSL2 GATA2 GJA1 HIF1A HLA-A IFNG IL10 IL2 IL4 IL5 IL6 JUN JUNB JUND MAF MAFG MMP1 MMP9 MT2A MYB MYC NFATC2 NPPA NR3C1 NTS PENK PLAU PTEN RNF187 SP1 TCF7L2 TGFB1 TH TIMP1 TP53 TRIP6 (see all 69) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	BAG1	BAG Cochaperone 1	Protein Coding	1
2	PENK	Proenkephalin	Protein Coding	1
3	RNF187	Ring Finger Protein 187	Protein Coding	1
4	DMTF1	Cyclin D Binding Myb Like Transcription Factor 1	Protein Coding	1
5	TRIP6	Thyroid Hormone Receptor Interactor 6	Protein Coding	1
6	CRTC1	CREB Regulated Transcription Coactivator 1	Protein Coding	1
7	ACTA1	Actin Alpha 1, Skeletal Muscle	Protein Coding	1
8	FOSL1	FOS Like 1, AP-1 Transcription Factor Subunit	Protein Coding	1
9	CCN1	Cellular Communication Network Factor 1	Protein Coding	1
10	FOSL2	FOS Like 2, AP-1 Transcription Factor Subunit	Protein Coding	1
11	DUSP1	Dual Specificity Phosphatase 1	Protein Coding	1
12	CREB1	CAMP Responsive Element Binding Protein 1	Protein Coding	1
13	TCF7L2	Transcription Factor 7 Like 2	Protein Coding	1
14	MAFG	MAF BZIP Transcription Factor G	Protein Coding	1
15	GATA2	GATA Binding Protein 2~Name Same As:- HGNC:18350	Protein Coding	1
16	IL10	Interleukin 10	Protein Coding	1
17	IL4	Interleukin 4	Protein Coding	1
18	IL5	Interleukin 5	Protein Coding	1
19	ELF1	E74 Like ETS Transcription Factor 1	Protein Coding	1
20	MAF	MAF BZIP Transcription Factor	Protein Coding	1
21	CSF2	Colony Stimulating Factor 2	Protein Coding	1
22	IFNG	Interferon Gamma	Protein Coding	1
23	IL2	Interleukin 2	Protein Coding	1
24	NFATC2	Nuclear Factor Of Activated T Cells 2	Protein Coding	1
25	HLA-A	Major Histocompatibility Complex, Class I, A	Protein Coding	1
26	ATF3	Activating Transcription Factor 3	Protein Coding	1
27	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	1
28	NPPA	Natriuretic Peptide A	Protein Coding	1
29	IL6	Interleukin 6	Protein Coding	1
30	ETS1	ETS Proto-Oncogene 1, Transcription Factor	Protein Coding	1
31	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	1
32	BCL2L11	BCL2 Like 11	Protein Coding	1
33	NR3C1	Nuclear Receptor Subfamily 3 Group C Member 1	Protein Coding	1
34	EGR1	Early Growth Response 1	Protein Coding	1
35	JUND	JunD Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
36	CBFB	Core-Binding Factor Subunit Beta	Protein Coding	1
37	FOSB	FosB Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
38	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
39	HIF1A	Hypoxia Inducible Factor 1 Subunit Alpha	Protein Coding	1
40	CCND1	Cyclin D1	Protein Coding	1
41	NTS	Neurotensin	Protein Coding	1
42	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	1
43	EDN1	Endothelin 1	Protein Coding	1
44	JUNB	JunB Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
45	COL1A2	Collagen Type I Alpha 2 Chain	Protein Coding	1
46	TH	Tyrosine Hydroxylase	Protein Coding	1
47	AGT	Angiotensinogen	Protein Coding	1
48	PTEN	Phosphatase And Tensin Homolog	Protein Coding	1
49	MYB	MYB Proto-Oncogene, Transcription Factor	Protein Coding	1
50	PLAU	Plasminogen Activator, Urokinase	Protein Coding	1
51	DMP1	Dentin Matrix Acidic Phosphoprotein 1	Protein Coding	1
52	TIMP1	TIMP Metallopeptidase Inhibitor 1	Protein Coding	1
53	MMP1	Matrix Metallopeptidase 1	Protein Coding	1
54	CTNNB1	Catenin Beta 1	Protein Coding	1
55	SP1	Sp1 Transcription Factor	Protein Coding	1
56	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
57	FABP4	Fatty Acid Binding Protein 4	Protein Coding	1
58	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
59	CDK1	Cyclin Dependent Kinase 1	Protein Coding	1
60	ATF2	Activating Transcription Factor 2	Protein Coding	1
61	COPS5	COP9 Signalosome Subunit 5	Protein Coding	1
62	GJA1	Gap Junction Protein Alpha 1	Protein Coding	1
63	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	1
64	TP53	Tumor Protein P53	Protein Coding	1
65	CDKN1B	Cyclin Dependent Kinase Inhibitor 1B	Protein Coding	1
66	MMP9	Matrix Metallopeptidase 9	Protein Coding	1
67	MT2A	Metallothionein 2A	Protein Coding	1
68	ESR1	Estrogen Receptor 1	Protein Coding	1
69	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1

Disorders associated with AP-1 transcription factor network SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Adrenocortical carcinoma	Enrichment	CDKN2A, CTNNB1, TP53	5.60
2	Bladder cancer	Enrichment	CDKN2A, CTNNB1, PTEN, TP53	4.88
3	Breast cancer	Enrichment	ESR1, IL2, JUN, PTEN, TP53	4.41
4	Human immunodeficiency virus type 1	Enrichment	CCL2, IFNG, IL10	4.01
5	Ovarian cancer	Enrichment	CDKN1B, CDKN2A, CTNNB1, PTEN, TP53	3.80
6	Precursor t-cell acute lymphoblastic leukemia	Enrichment	CDKN2A, MYB, MYC	3.68
7	Histiocytoid hemangioma	Enrichment	FOS, FOSB	3.60
8	Acute megakaryocytic leukemia	Enrichment	PTEN, TP53	3.60
9	Li-fraumeni syndrome	Enrichment	CDKN2A, TP53	3.42
10	Il10-related early-onset inflammatory bowel disease	Enrichment	IL10, TGFB1	3.42
11	Squamous cell carcinoma, head and neck	Enrichment	PTEN, TP53	3.28
12	Gallbladder cancer	Enrichment	CTNNB1, TP53	3.28
13	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	CDKN2A, TP53	3.28
14	Adult hepatocellular carcinoma	Enrichment	CTNNB1, TP53	3.05
15	Primary hyperaldosteronism	Enrichment	NR3C1, TP53	3.05
16	Colorectal cancer	Enrichment	CCND1, CTNNB1, EP300, TP53	3.00
17	Leukemia, chronic lymphocytic	Enrichment	CCND1, TP53	2.95
18	Melanoma	Enrichment	CDKN2A, PTEN	2.95
19	Gastric cancer	Enrichment	CDKN2A, PTEN, TP53	2.87
20	Myelodysplastic syndrome	Enrichment	GATA2, TP53	2.87
21	Hereditary breast carcinoma	Enrichment	ESR1, PTEN, TP53	2.84
22	Lip and oral cavity carcinoma	Enrichment	CDKN2A, TP53	2.79
23	Rhabdomyosarcoma	Enrichment	PTEN, TP53	2.53
24	Diffuse large b-cell lymphoma	Enrichment	PTEN, TP53	2.38
25	Inherited cancer-predisposing syndrome	Enrichment	CDKN1B, CDKN2A, PTEN, TP53	2.34
26	Hepatoblastoma	Enrichment	CTNNB1, TP53	2.30
27	Palmoplantar keratoderma and congenital alopecia 1	Enrichment	GJA1	2.29
28	Ehlers-danlos syndrome, cardiac valvular type	Enrichment	COL1A2	2.29
29	Hypophosphatemic rickets, autosomal recessive, 1	Enrichment	DMP1	2.29
30	Hypoplastic left heart syndrome 1	Enrichment	GJA1	2.29
31	Vacterl association with hydrocephalus	Enrichment	PTEN	2.29
32	Cataract 21, multiple types	Enrichment	MAF	2.29
33	Congenital myopathy 2a, typical, autosomal dominant	Enrichment	ACTA1	2.29
34	Oculodentodigital dysplasia	Enrichment	GJA1	2.29
35	Glucocorticoid resistance, generalized	Enrichment	NR3C1	2.29
36	Myopathy, scapulohumeroperoneal	Enrichment	ACTA1	2.29
37	Craniometaphyseal dysplasia, autosomal recessive	Enrichment	GJA1	2.29
38	Auriculocondylar syndrome 3	Enrichment	EDN1	2.29
39	Immunodeficiency 69	Enrichment	IFNG	2.29
40	Bone marrow failure syndrome 5	Enrichment	TP53	2.29
41	Combined osteogenesis imperfecta and ehlers-danlos syndrome 2	Enrichment	COL1A2	2.29
42	Lymphedema, primary, with myelodysplasia	Enrichment	GATA2	2.29
43	Graft-versus-host disease	Enrichment	IL10	2.29
44	Papilloma of choroid plexus	Enrichment	TP53	2.29
45	Basal cell carcinoma 7	Enrichment	TP53	2.29
46	Anaplastic thyroid carcinoma	Enrichment	TP53	2.29
47	Ayme-gripp syndrome	Enrichment	MAF	2.29
48	Oculodentodigital dysplasia, autosomal recessive	Enrichment	GJA1	2.29
49	Papillary tumor of the pineal region	Enrichment	PTEN	2.29
50	Question mark ears, isolated	Enrichment	EDN1	2.29
51	Birdshot chorioretinopathy	Enrichment	HLA-A	2.29
52	Neuroendocrine tumor	Enrichment	CDKN1B	2.29
53	Immunodeficiency 21	Enrichment	GATA2	2.29
54	Congenital myopathy 2b, severe infantile, autosomal recessive	Enrichment	ACTA1	2.29
55	Glioma susceptibility 2	Enrichment	PTEN	2.29
56	Ductal carcinoma in situ	Enrichment	TP53	2.29
57	Erythrokeratodermia variabilis et progressiva 3	Enrichment	GJA1	2.29
58	Deafness-lymphedema-leukemia syndrome	Enrichment	GATA2	2.29
59	Congenital myopathy 2c, severe infantile, autosomal dominant	Enrichment	ACTA1	2.29
60	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	2.29
61	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	2.29
62	Adenoid ameloblastoma	Enrichment	CTNNB1	2.29
63	Cdkn2a cancer predisposition	Enrichment	CDKN2A	2.29
64	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	2.29
65	Choroid plexus cancer	Enrichment	TP53	2.29
66	Zebra body myopathy	Enrichment	ACTA1	2.29
67	Aplasia cutis-enamel dysplasia syndrome	Enrichment	FOSL2	2.29
68	Pleomorphic xanthoastrocytoma	Enrichment	TP53	2.29
69	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	Enrichment	PTEN	2.29
70	Actin-accumulation myopathy	Enrichment	ACTA1	2.29
71	Microcystic stromal tumor	Enrichment	CTNNB1	2.29
72	Hepatocellular carcinoma	Enrichment	CTNNB1, TP53	2.26
73	Pancreatic cancer	Enrichment	CDKN2A, TP53	2.15
74	Prostate cancer	Enrichment	PTEN, TP53	2.02
75	Melanoma-astrocytoma syndrome	Enrichment	CDKN2A	1.99
76	Burkitt lymphoma	Enrichment	MYC	1.99
77	Adrenocortical carcinoma, hereditary	Enrichment	TP53	1.99
78	Camurati-engelmann disease 1	Enrichment	TGFB1	1.99
79	Bruck syndrome 1	Enrichment	COL1A2	1.99
80	Galactosemia ii	Enrichment	NR3C1	1.99
81	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	1.99
82	Quebec platelet disorder	Enrichment	PLAU	1.99
83	Cervical cancer	Enrichment	TP53	1.99
84	Severe cutaneous adverse reaction	Enrichment	HLA-A	1.99
85	Histiocytoma, angiomatoid fibrous	Enrichment	CREB1	1.99
86	Segawa syndrome, autosomal recessive	Enrichment	TH	1.99
87	Melanoma, cutaneous malignant 2	Enrichment	CDKN2A	1.99
88	Atrial fibrillation, familial, 6	Enrichment	NPPA	1.99
89	Developmental and epileptic encephalopathy 28	Enrichment	MAF	1.99
90	Hallermann-streiff syndrome	Enrichment	GJA1	1.99
91	Lymphoma, hodgkin, classic	Enrichment	TP53	1.99
92	Syndactyly, type iii	Enrichment	GJA1	1.99
93	Syndactyly, type v	Enrichment	GJA1	1.99
94	Multiple endocrine neoplasia, type iv	Enrichment	CDKN1B	1.99
95	Spinocerebellar ataxia, autosomal recessive 12	Enrichment	MAF	1.99
96	Ehlers-danlos syndrome, arthrochalasia type, 2	Enrichment	COL1A2	1.99
97	Menke-hennekam syndrome 2	Enrichment	EP300	1.99
98	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.99
99	Autosomal recessive hypophosphatemic rickets	Enrichment	DMP1	1.99
100	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	1.99
101	Craniometaphyseal dysplasia	Enrichment	GJA1	1.99
102	Recessive dystrophic epidermolysis bullosa	Enrichment	MMP1	1.99
103	Acute basophilic leukemia	Enrichment	MYB	1.99
104	Melanoma-pancreatic cancer syndrome	Enrichment	CDKN2A	1.99
105	Cleidocranial dysplasia 2	Enrichment	CBFB	1.99
106	Camurati-engelmann disease	Enrichment	TGFB1	1.99
107	Congenital fibrosarcoma	Enrichment	TP53	1.99
108	Metaphyseal anadysplasia 2	Enrichment	MMP9	1.99
109	Li-fraumeni syndrome 1	Enrichment	TP53	1.99
110	Sarcoma	Enrichment	TP53	1.99
111	Angiocentric glioma	Enrichment	MYB	1.99
112	Cervix carcinoma	Enrichment	TP53	1.99
113	Hodgkin's lymphoma	Enrichment	TP53	1.99
114	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.99
115	Metaphyseal anadysplasia	Enrichment	MMP9	1.99
116	Ehlers-danlos/osteogenesis imperfecta syndrome	Enrichment	COL1A2	1.99
117	Joint contractures, osteochondromas, and b-cell lymphoma	Enrichment	NFATC2	1.99
118	Vacterl with hydrocephalus	Enrichment	PTEN	1.99
119	Isolated atrial standstill	Enrichment	NPPA	1.99
120	Dentinogenesis imperfecta	Enrichment	COL1A2	1.99
121	Teratoma	Enrichment	CTNNB1	1.99
122	Juvenile polyposis of infancy	Enrichment	PTEN	1.99
123	Pleomorphic rhabdomyosarcoma	Enrichment	TP53	1.99
124	Desmoid disease, hereditary	Enrichment	CTNNB1	1.82
125	Jacobsen syndrome	Enrichment	ETS1	1.82
126	Dystonia, dopa-responsive	Enrichment	TH	1.82
127	Tuberous sclerosis 1	Enrichment	IFNG	1.82
128	Osteogenic sarcoma	Enrichment	TP53	1.82
129	Hepatitis c virus	Enrichment	IFNG	1.82
130	Nasopharyngeal carcinoma	Enrichment	TP53	1.82
131	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.82
132	Estrogen resistance	Enrichment	ESR1	1.82
133	Tuberous sclerosis 2	Enrichment	IFNG	1.82
134	Atrial standstill 2	Enrichment	NPPA	1.82
135	Anus, imperforate	Enrichment	CTNNB1	1.82
136	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.82
137	Desmoid tumor	Enrichment	CTNNB1	1.82
138	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	MYC	1.82
139	Atypical teratoid rhabdoid tumor	Enrichment	TP53	1.82
140	Anaplastic astrocytoma	Enrichment	TP53	1.82
141	Squamous cell carcinoma	Enrichment	TP53	1.82
142	Adenocarcinoma	Enrichment	TP53	1.82
143	Migraine without aura	Enrichment	ESR1	1.82
144	Laryngeal squamous cell carcinoma	Enrichment	PTEN	1.82
145	Bone osteosarcoma	Enrichment	TP53	1.82
146	Adenoid cystic carcinoma	Enrichment	MYB	1.82
147	High bone mass osteogenesis imperfecta	Enrichment	COL1A2	1.82
148	Melanoma of soft tissue	Enrichment	CREB1	1.82
149	Enchondromatosis	Enrichment	HIF1A	1.82
150	Systemic lupus erythematosus	Enrichment	ETS1, IL10	1.78
151	Leukemia, acute myeloid	Enrichment	GATA2, TP53	1.76
152	Type 2 diabetes mellitus	Enrichment	IL6, TCF7L2	1.72
153	Kaposi sarcoma	Enrichment	IL6	1.69
154	Ehlers-danlos syndrome, arthrochalasia type, 1	Enrichment	COL1A2	1.69
155	Small cell cancer of the lung	Enrichment	TP53	1.69
156	Nemaline myopathy 2	Enrichment	ACTA1	1.69
157	Thyroid cancer, nonmedullary, 1	Enrichment	TP53	1.69
158	Auriculocondylar syndrome 1	Enrichment	EDN1	1.69
159	Pilomatrixoma	Enrichment	CTNNB1	1.69
160	Alazami syndrome	Enrichment	CTNNB1	1.69
161	Congenital generalized lipodystrophy	Enrichment	FOS	1.69
162	Mantle cell lymphoma	Enrichment	CCND1	1.69
163	Arthrogryposis multiplex congenita 3, myogenic type	Enrichment	ESR1	1.69
164	Lung sarcomatoid carcinoma	Enrichment	TP53	1.69
165	Embryonal rhabdomyosarcoma	Enrichment	TP53	1.69
166	Craniopharyngioma	Enrichment	CTNNB1	1.69
167	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	CBFB	1.69
168	Congenital blue dot cataract	Enrichment	MAF	1.69
169	Osteogenesis imperfecta with normal sclerae, dominant form	Enrichment	COL1A2	1.69
170	Primary hyperparathyroidism	Enrichment	CDKN1B	1.69
171	Intermediate nemaline myopathy	Enrichment	ACTA1	1.69
172	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	1.69
173	Glioma	Enrichment	PTEN	1.69
174	Pseudomyogenic hemangioendothelioma	Enrichment	FOSB	1.69
175	Enchondromatosis, multiple, ollier type	Enrichment	HIF1A	1.60
176	Alzheimer disease 2	Enrichment	PLAU	1.60
177	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	1.60
178	Von hippel-lindau syndrome	Enrichment	CCND1	1.60
179	Congenital myopathy 3 with rigid spine	Enrichment	ACTA1	1.60
180	Rhabdomyosarcoma 2	Enrichment	TP53	1.60
181	Macrocephaly/autism syndrome	Enrichment	PTEN	1.60
182	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	1.60
183	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.60
184	Lymphoma	Enrichment	TP53	1.60
185	Hemangioma	Enrichment	PTEN	1.60
186	Cleft upper lip	Enrichment	GJA1	1.60
187	Hemimegalencephaly	Enrichment	PTEN	1.60
188	Severe congenital nemaline myopathy	Enrichment	ACTA1	1.60
189	Idiopathic aplastic anemia	Enrichment	IFNG	1.60
190	Ehlers-danlos syndrome, classic type, 1	Enrichment	COL1A2	1.52
191	Osteogenesis imperfecta, type i	Enrichment	COL1A2	1.52
192	Cowden syndrome 1	Enrichment	PTEN	1.52
193	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.52
194	Rubinstein-taybi syndrome 1	Enrichment	EP300	1.52
195	Type 1 diabetes mellitus	Enrichment	IL6	1.52
196	Renal tubular dysgenesis	Enrichment	AGT	1.52
197	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	EP300	1.52
198	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	1.52
199	Breast adenocarcinoma	Enrichment	TP53	1.52
200	Lung squamous cell carcinoma	Enrichment	CDKN2A	1.52
201	Classic ehlers-danlos syndrome	Enrichment	COL1A2	1.52
202	Typical nemaline myopathy	Enrichment	ACTA1	1.52
203	Hereditary breast ovarian cancer syndrome	Enrichment	PTEN, TP53	1.50
204	Myeloma, multiple	Enrichment	CCND1, TP53	1.48
205	Esophageal cancer	Enrichment	TP53	1.45
206	Multiple endocrine neoplasia, type i	Enrichment	CDKN1B	1.45
207	Osteogenesis imperfecta, type ii	Enrichment	COL1A2	1.45
208	Thyroid cancer, nonmedullary, 2	Enrichment	PTEN	1.45
209	Multiple enchondromatosis, maffucci type	Enrichment	HIF1A	1.45
210	Essential thrombocythemia	Enrichment	TP53	1.45
211	Follicular thyroid carcinoma	Enrichment	PTEN	1.45
212	Childhood-onset nemaline myopathy	Enrichment	ACTA1	1.45
213	Hypophosphatemic rickets	Enrichment	DMP1	1.45
214	Glioma susceptibility 1	Enrichment	TP53	1.40
215	Erythrokeratodermia variabilis et progressiva 1	Enrichment	GJA1	1.40
216	Lymphoma, non-hodgkin, familial	Enrichment	TP53	1.40
217	Exudative vitreoretinopathy	Enrichment	CTNNB1	1.40
218	Hypoplastic left heart syndrome	Enrichment	GJA1	1.40
219	Cataract - microcornea syndrome	Enrichment	MAF	1.40
220	Rheumatoid arthritis	Enrichment	IL10	1.35
221	Charge syndrome	Enrichment	EP300	1.35
222	Inflammatory bowel disease 1	Enrichment	IL6	1.35
223	Cowden syndrome	Enrichment	PTEN	1.35
224	Cataract 30, multiple types	Enrichment	MAF	1.30
225	Aplastic anemia	Enrichment	IFNG	1.30
226	Nemaline myopathy	Enrichment	ACTA1	1.30
227	Familial colorectal cancer	Enrichment	TP53	1.30
228	Primary bone dysplasia	Enrichment	COL1A2	1.30
229	Migraine with or without aura 1	Enrichment	ESR1	1.26
230	Meningioma, familial	Enrichment	PTEN	1.26
231	Leukemia, acute lymphoblastic	Enrichment	CDKN2A	1.26
232	Osteochondrodysplasia	Enrichment	COL1A2	1.26
233	Uterine corpus cancer	Enrichment	PTEN	1.26
234	Meningioma	Enrichment	PTEN	1.23
235	Osteogenesis imperfecta, type iv	Enrichment	COL1A2	1.19
236	Osteoporosis	Enrichment	COL1A2	1.16
237	Medulloblastoma	Enrichment	CTNNB1	1.16
238	Lung cancer susceptibility 3	Enrichment	TP53	1.16
239	Polydactyly, postaxial, type a1	Enrichment	EP300	1.13
240	Congenital myopathy 4a, autosomal dominant	Enrichment	ACTA1	1.13
241	Osteogenesis imperfecta, type iii	Enrichment	COL1A2	1.13
242	Rare genetic intellectual disability	Enrichment	EP300	1.13
243	Gliosarcoma	Enrichment	TP53	1.11
244	Alzheimer disease, familial, 1	Enrichment	PLAU	1.08
245	Hypertension, essential	Enrichment	AGT	1.08
246	Melanoma, cutaneous malignant 1	Enrichment	CDKN2A	1.08
247	Polycystic liver disease	Enrichment	CTNNB1	1.08
248	Giant cell glioblastoma	Enrichment	TP53	1.08
249	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	1.08
250	Neuromuscular disease	Enrichment	ACTA1	1.06
251	Arteriovenous malformations of the brain	Enrichment	IL6	1.03
252	Behcet syndrome	Enrichment	IL10	1.03
253	Congenital myopathy	Enrichment	ACTA1	1.03
254	Ehlers-danlos syndrome	Enrichment	COL1A2	1.03
255	Congenital nervous system abnormality	Enrichment	CTNNB1, PTEN	0.99
256	Nervous system disease	Enrichment	CTNNB1, PTEN	0.99
257	Cardiomyopathy, dilated, 1a	Enrichment	NFATC2	0.99
258	Endometrial cancer	Enrichment	PTEN	0.99
259	Centronuclear myopathy	Enrichment	ACTA1	0.99
260	Myocardial infarction	Enrichment	ESR1	0.97
261	Diamond-blackfan anemia 1	Enrichment	TP53	0.96
262	Brittle bone disorder	Enrichment	COL1A2	0.96
263	Familial atrial fibrillation	Enrichment	NPPA	0.94
264	Developmental and epileptic encephalopathy 1	Enrichment	MAF	0.92
265	Hydrops fetalis, nonimmune	Enrichment	ACTA1	0.91
266	Microcephaly	Enrichment	CTNNB1, EP300	0.89
267	Severe covid-19	Enrichment	HLA-A	0.86
268	Non-immune hydrops fetalis	Enrichment	ACTA1	0.83
269	Cystic fibrosis	Enrichment	TGFB1	0.82
270	Dystonia	Enrichment	TH	0.79
271	Diamond-blackfan anemia	Enrichment	TP53	0.77
272	Fetal akinesia deformation sequence 1	Enrichment	ACTA1	0.76
273	Myopathy	Enrichment	ACTA1	0.73
274	Benign epilepsy with centrotemporal spikes	Enrichment	MAF	0.72
275	Distal arthrogryposis	Enrichment	ACTA1	0.71
276	Centralopathic epilepsy	Enrichment	MAF	0.71
277	West syndrome	Enrichment	MAF	0.70
278	Autism	Enrichment	TCF7L2	0.51
279	Dilated cardiomyopathy	Enrichment	ACTA1	0.47
280	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	GJA1	0.44
281	Autism spectrum disorder	Enrichment	PTEN	0.37
282	Complex neurodevelopmental disorder	Enrichment	TCF7L2	0.33

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

AP-1 transcription factor network

Pathway Network for AP-1 transcription factor network

Member Pathways for AP-1 transcription factor network

Pathways in the AP-1 transcription factor network SuperPath

Associated Genes for AP-1 transcription factor network

Associated Disorders for AP-1 transcription factor network

Disorders associated with AP-1 transcription factor network SuperPath

STRING Interaction Network for AP-1 transcription factor network

Sources for AP-1 transcription factor network