ApoE and miR-146 in inflammation and atherosclerosis

No Pathway Network information available for ApoE and miR-146 in inflammation and atherosclerosis

#	Name	Source	Genes
1	ApoE and miR-146 in inflammation and atherosclerosis	WikiPathways	APOE IRAK1 MIR146A NFKB2 RELA SPI1 TLR2 TLR4 TRAF6 (see all 9) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	TRAF6	TNF Receptor Associated Factor 6	Protein Coding	1
2	TLR4	Toll Like Receptor 4	Protein Coding	1
3	TLR2	Toll Like Receptor 2	Protein Coding	1
4	SPI1	Spi-1 Proto-Oncogene	Protein Coding	1
5	RELA	RELA Proto-Oncogene, NF-KB Subunit	Protein Coding	1
6	NFKB2	Nuclear Factor Kappa B Subunit 2	Protein Coding	1
7	MIR146A	MicroRNA 146a	RNA Gene	1
8	IRAK1	Interleukin 1 Receptor Associated Kinase 1	Protein Coding	1
9	APOE	Apolipoprotein E	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Leprosy 3	Enrichment	TLR2	3.18
2	Sea-blue histiocyte disease	Enrichment	APOE	3.18
3	Lipoprotein glomerulopathy	Enrichment	APOE	3.18
4	Agammaglobulinemia 10, autosomal dominant	Enrichment	SPI1	3.18
5	Macular degeneration, age-related, 10	Enrichment	TLR4	3.18
6	Deficiency in anterior pituitary function - variable immunodeficiency syndrome	Enrichment	NFKB2	3.18
7	Agammaglobulinemia	Enrichment	SPI1	3.18
8	Alzheimer disease 3	Enrichment	APOE	2.88
9	Immunodeficiency, common variable, 10	Enrichment	NFKB2	2.88
10	Autoinflammatory disease, familial, behcet-like 3	Enrichment	RELA	2.88
11	Hyperlipoproteinemia, type iii	Enrichment	APOE	2.88
12	Rela fusion-positive ependymoma	Enrichment	RELA	2.88
13	Alzheimer disease 4	Enrichment	APOE	2.70
14	Macular degeneration, age-related, 1	Enrichment	APOE	2.58
15	Immunodeficiency, common variable, 1	Enrichment	NFKB2	2.58
16	Pediatric systemic lupus erythematosus	Enrichment	IRAK1	2.58
17	Ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant	Enrichment	TRAF6	2.48
18	Alzheimer disease 2	Enrichment	APOE	2.48
19	Lipid metabolism disorder	Enrichment	APOE	2.40
20	Common variable immunodeficiency	Enrichment	NFKB2	2.33
21	Autosomal non-syndromic agammaglobulinemia	Enrichment	SPI1	2.18
22	Alzheimer's disease	Enrichment	APOE	2.07
23	Familial hypercholesterolemia	Enrichment	APOE	2.00
24	Alzheimer disease, familial, 1	Enrichment	APOE	1.95
25	Behcet syndrome	Enrichment	TLR4	1.90
26	Systemic lupus erythematosus	Enrichment	IRAK1	1.59
27	Colorectal cancer	Enrichment	TLR2	1.25

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for ApoE and miR-146 in inflammation and atherosclerosis