Apoptosis and survival BAD phosphorylation

No Pathway Network information available for Apoptosis and survival BAD phosphorylation

Pathways in the Apoptosis and survival BAD phosphorylation SuperPath

#	Name	Source	Genes
1	Apoptosis and survival BAD phosphorylation	GeneGo (Thomson Reuters)	ADCY1 AKT1 AKT2 AKT3 BAD BAX BCL2 BCL2L1 BECN1 CDK1 CYCS EGFR GNAS GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GRB2 HRAS IGF1R IRS1 MAP2K1 MAP2K2 MAPK1 MAPK3 MAPK8 PDP1 PDPK1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PPM1A PPM1B PPM1D PPM1F PPM1G PPM1L PPP1CA PPP2CA PPP2CB PPP3CA PPP3CB PPP3CC PPTC7 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PTPN11 RAF1 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KB1 RPS6KB2 SFN SHC1 SOS1 SOS2 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 84) (see less)
2	BAD Phosphorylation	QIAGEN	ADCY1 ADCY2 ADCY3 AKT1 APAF1 BAD BCL2 BCL2L1 CASP9 CYCS EGF EGFR GNA11 GNA12 GNA13 GNA14 GNA15 GNAS GNB1 GNB2 GNB3 GNB4 GNB5 GNG2 GNG3 GNG4 GRB2 HRAS IGF1 IGF1R IRS1 MAP2K1 MAP2K2 MAPK1 MAPK3 PDPK1 PIK3CD PIK3R3 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R2B PPP2R2C PPP2R3A PPP2R3B PPP2R5A PPP2R5B PPP2R5C PPP2R5E PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRKACG PRKAR2B PTPA RAF1 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KA5 RPS6KA6 RPS6KB1 SOS1 SOS2 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 75) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ADCY1	Adenylate Cyclase 1	Protein Coding	2
2	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	2
3	BAD	BCL2 Associated Agonist Of Cell Death	Protein Coding	2
4	BCL2	BCL2 Apoptosis Regulator	Protein Coding	2
5	BCL2L1	BCL2 Like 1	Protein Coding	2
6	EGFR	Epidermal Growth Factor Receptor	Protein Coding	2
7	GNAS	GNAS Complex Locus	Protein Coding	2
8	GNB1	G Protein Subunit Beta 1	Protein Coding	2
9	GNB2	G Protein Subunit Beta 2	Protein Coding	2
10	GNB3	G Protein Subunit Beta 3	Protein Coding	2
11	GNG3	G Protein Subunit Gamma 3	Protein Coding	2
12	GNG4	G Protein Subunit Gamma 4	Protein Coding	2
13	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	2
14	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	2
15	IGF1R	Insulin Like Growth Factor 1 Receptor	Protein Coding	2
16	IRS1	Insulin Receptor Substrate 1	Protein Coding	2
17	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	2
18	PIK3CD	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta	Protein Coding	2
19	PPP2CA	Protein Phosphatase 2 Catalytic Subunit Alpha	Protein Coding	2
20	PPP2CB	Protein Phosphatase 2 Catalytic Subunit Beta	Protein Coding	2
21	PPP3CA	Protein Phosphatase 3 Catalytic Subunit Alpha	Protein Coding	2
22	PPP3CB	Protein Phosphatase 3 Catalytic Subunit Beta	Protein Coding	2
23	PPP3CC	Protein Phosphatase 3 Catalytic Subunit Gamma	Protein Coding	2
24	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	2
25	PRKAR2B	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Beta	Protein Coding	2
26	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	2
27	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	2
28	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	2
29	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	2
30	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	2
31	RPS6KA1	Ribosomal Protein S6 Kinase A1	Protein Coding	2
32	RPS6KA2	Ribosomal Protein S6 Kinase A2	Protein Coding	2
33	RPS6KA3	Ribosomal Protein S6 Kinase A3	Protein Coding	2
34	RPS6KB1	Ribosomal Protein S6 Kinase B1	Protein Coding	2
35	SOS1	SOS Ras/Rac Guanine Nucleotide Exchange Factor 1	Protein Coding	2
36	SOS2	SOS Ras/Rho Guanine Nucleotide Exchange Factor 2	Protein Coding	2
37	YWHAB	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Beta	Protein Coding	2
38	YWHAE	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon	Protein Coding	2
39	YWHAG	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Gamma	Protein Coding	2
40	YWHAH	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Eta	Protein Coding	2
41	YWHAZ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta	Protein Coding	2
42	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	2
43	GNB5	G Protein Subunit Beta 5	Protein Coding	2
44	YWHAQ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Theta	Protein Coding	2
45	CYCS	Cytochrome C, Somatic	Protein Coding	2
46	GNG2	G Protein Subunit Gamma 2	Protein Coding	2
47	GNB4	G Protein Subunit Beta 4	Protein Coding	2
48	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	1
49	BAX	BCL2 Associated X, Apoptosis Regulator	Protein Coding	1
50	CDK1	Cyclin Dependent Kinase 1	Protein Coding	1
51	GNG5	G Protein Subunit Gamma 5	Protein Coding	1
52	GNG7	G Protein Subunit Gamma 7	Protein Coding	1
53	GNG10	G Protein Subunit Gamma 10	Protein Coding	1
54	GNG11	G Protein Subunit Gamma 11	Protein Coding	1
55	GNGT1	G Protein Subunit Gamma Transducin 1	Protein Coding	1
56	GNGT2	G Protein Subunit Gamma Transducin 2	Protein Coding	1
57	SFN	Stratifin	Protein Coding	1
58	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
59	PIK3CB	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta	Protein Coding	1
60	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	1
61	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	1
62	PPM1A	Protein Phosphatase, Mg2+/Mn2+ Dependent 1A	Protein Coding	1
63	PPM1B	Protein Phosphatase, Mg2+/Mn2+ Dependent 1B	Protein Coding	1
64	PPM1G	Protein Phosphatase, Mg2+/Mn2+ Dependent 1G	Protein Coding	1
65	PPP1CA	Protein Phosphatase 1 Catalytic Subunit Alpha	Protein Coding	1
66	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	1
67	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	1
68	PRKAR1A	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha	Protein Coding	1
69	PRKAR1B	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Beta	Protein Coding	1
70	PRKAR2A	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Alpha	Protein Coding	1
71	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	1
72	PTPN11	Protein Tyrosine Phosphatase Non-Receptor Type 11	Protein Coding	1
73	RPS6KB2	Ribosomal Protein S6 Kinase B2	Protein Coding	1
74	SHC1	SHC Adaptor Protein 1	Protein Coding	1
75	PPM1D	Protein Phosphatase, Mg2+/Mn2+ Dependent 1D	Protein Coding	1
76	BECN1	Beclin 1	Protein Coding	1
77	PPM1F	Protein Phosphatase, Mg2+/Mn2+ Dependent 1F	Protein Coding	1
78	AKT3	AKT Serine/Threonine Kinase 3	Protein Coding	1
79	GNG13	G Protein Subunit Gamma 13	Protein Coding	1
80	PDP1	Pyruvate Dehydrogenase Phosphatase Catalytic Subunit 1	Protein Coding	1
81	GNG12	G Protein Subunit Gamma 12	Protein Coding	1
82	GNG8	G Protein Subunit Gamma 8	Protein Coding	1
83	PPM1L	Protein Phosphatase, Mg2+/Mn2+ Dependent 1L	Protein Coding	1
84	PPTC7	Protein Phosphatase Targeting COQ7	Protein Coding	1
85	ADCY2	Adenylate Cyclase 2	Protein Coding	1
86	ADCY3	Adenylate Cyclase 3	Protein Coding	1
87	APAF1	Apoptotic Peptidase Activating Factor 1	Protein Coding	1
88	CASP9	Caspase 9	Protein Coding	1
89	EGF	Epidermal Growth Factor	Protein Coding	1
90	GNA11	G Protein Subunit Alpha 11	Protein Coding	1
91	GNA12	G Protein Subunit Alpha 12	Protein Coding	1
92	GNA13	G Protein Subunit Alpha 13	Protein Coding	1
93	GNA14	G Protein Subunit Alpha 14	Protein Coding	1
94	GNA15	G Protein Subunit Alpha 15	Protein Coding	1
95	IGF1	Insulin Like Growth Factor 1	Protein Coding	1
96	PPP2R1A	Protein Phosphatase 2 Scaffold Subunit Aalpha	Protein Coding	1
97	PPP2R1B	Protein Phosphatase 2 Scaffold Subunit Abeta	Protein Coding	1
98	PPP2R2A	Protein Phosphatase 2 Regulatory Subunit Balpha	Protein Coding	1
99	PPP2R2B	Protein Phosphatase 2 Regulatory Subunit Bbeta	Protein Coding	1
100	PPP2R2C	Protein Phosphatase 2 Regulatory Subunit Bgamma	Protein Coding	1
101	PPP2R3A	Protein Phosphatase 2 Regulatory Subunit B''''Alpha	Protein Coding	1
102	PTPA	Protein Phosphatase 2 Phosphatase Activator	Protein Coding	1
103	PPP2R5A	Protein Phosphatase 2 Regulatory Subunit B''Alpha	Protein Coding	1
104	PPP2R5B	Protein Phosphatase 2 Regulatory Subunit B''Beta	Protein Coding	1
105	PPP2R5C	Protein Phosphatase 2 Regulatory Subunit B''Gamma	Protein Coding	1
106	PPP2R5E	Protein Phosphatase 2 Regulatory Subunit B''Epsilon	Protein Coding	1
107	PPP3R1	Protein Phosphatase 3 Regulatory Subunit B, Alpha	Protein Coding	1
108	PPP3R2	Protein Phosphatase 3 Regulatory Subunit B, Beta	Protein Coding	1
109	PPP2R3B	Protein Phosphatase 2 Regulatory Subunit B''''Beta~Name Same As:- HGNC:9310	Protein Coding	1
110	RPS6KA4	Ribosomal Protein S6 Kinase A4	Protein Coding	1
111	RPS6KA5	Ribosomal Protein S6 Kinase A5	Protein Coding	1
112	RPS6KA6	Ribosomal Protein S6 Kinase A6	Protein Coding	1

Disorders associated with Apoptosis and survival BAD phosphorylation SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Noonan syndrome 1	Enrichment	HRAS, MAP2K1, MAP2K2, PTPN11, RAF1, SOS1, SOS2	10.24
2	Rasopathy	Enrichment	HRAS, MAP2K1, MAP2K2, PTPN11, RAF1, SOS1, SOS2	9.83
3	Noonan syndrome and noonan-related syndrome	Enrichment	HRAS, MAP2K1, MAP2K2, PTPN11, RAF1, SOS1	9.62
4	Noonan syndrome 3	Enrichment	HRAS, PTPN11, RAF1, SOS1	7.33
5	Lung non-small cell carcinoma	Enrichment	EGFR, HRAS, MAP2K1, PIK3CA	6.36
6	Specific learning disability	Enrichment	MAPK1, PTPN11, RPS6KA3, YWHAG	6.36
7	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	AKT3, PIK3CA, PIK3R2	6.04
8	Arteriovenous malformation	Enrichment	HRAS, MAP2K1, PIK3CA	4.73
9	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS, MAP2K1, PIK3CA	4.57
10	Pigmented nodular adrenocortical disease, primary, 1	Enrichment	GNAS, PRKAR1A	4.42
11	Lip and oral cavity carcinoma	Enrichment	EGFR, HRAS, PIK3CA	4.32
12	Anastomosing haemangioma	Enrichment	GNA11, GNA14	4.04
13	Breast cancer	Enrichment	AKT1, GNG3, PIK3CA, PPM1D, SHC1	4.00
14	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA, PIK3R1	3.95
15	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3CD, PIK3R1	3.95
16	Immunodeficiency 14	Enrichment	PIK3CD, PIK3R1	3.95
17	Cardiofaciocutaneous syndrome 1	Enrichment	MAP2K1, MAP2K2	3.75
18	Cardiofaciocutaneous syndrome	Enrichment	MAP2K1, MAP2K2	3.75
19	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	AKT3, PIK3R2	3.65
20	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	PTPN11, YWHAZ	3.65
21	Noonan syndrome with multiple lentigines	Enrichment	PTPN11, RAF1	3.65
22	Autosomal dominant non-syndromic intellectual disability	Enrichment	GNB1, PPM1D, PPP3CA, YWHAZ	3.60
23	Insulin-like growth factor i	Enrichment	IGF1, IGF1R	3.53
24	Hemimegalencephaly	Enrichment	AKT3, PIK3CA	3.43
25	Cowden syndrome 1	Enrichment	EGFR, PIK3CA	3.25
26	Breast adenocarcinoma	Enrichment	AKT1, PIK3CA	3.25
27	Lung squamous cell carcinoma	Enrichment	EGFR, PIK3CA	3.25
28	Bladder cancer	Enrichment	EGFR, HRAS, PIK3CA	3.13
29	Nevus, epidermal	Enrichment	HRAS, PIK3CA	3.11
30	Capillary malformation-arteriovenous malformation 1	Enrichment	MAP2K1, PIK3CA	3.11
31	Melanocytic nevus syndrome, congenital	Enrichment	HRAS, RAF1	3.08
32	Microcephaly	Enrichment	GNB1, IGF1R, MAPK1, PTPN11, YWHAG	3.01
33	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	2.88
34	Cowden syndrome	Enrichment	AKT1, PIK3CA	2.88
35	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3CD, PIK3R1	2.78
36	Colorectal cancer	Enrichment	AKT1, BAX, PIK3CA, PIK3R1	2.69
37	Meningioma	Enrichment	AKT1, PIK3CA	2.62
38	Hereditary breast carcinoma	Enrichment	AKT1, PIK3CA, PPM1D	2.60
39	Nk-cell enteropathy	Enrichment	IGF1R, PIK3CB	2.55
40	Ovarian cancer	Enrichment	AKT1, EGFR, PIK3CA, PPM1D	2.45
41	Proteus syndrome	Enrichment	AKT1	2.26
42	Hypocalciuric hypercalcemia, familial, type ii	Enrichment	GNA11	2.26
43	Coffin-lowry syndrome	Enrichment	RPS6KA3	2.26
44	Noonan syndrome 5	Enrichment	RAF1	2.26
45	Hypomagnesemia 4, renal	Enrichment	EGF	2.26
46	Noonan syndrome 4	Enrichment	SOS1	2.26
47	Pseudohypoparathyroidism, type ic	Enrichment	GNAS	2.26
48	Spinocerebellar ataxia 12	Enrichment	PPP2R2B	2.26
49	Melorheostosis, isolated	Enrichment	MAP2K1	2.26
50	Osseous heteroplasia, progressive	Enrichment	GNAS	2.26
51	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.26
52	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	2.26
53	Noonan syndrome 9	Enrichment	SOS2	2.26
54	Deafness, autosomal recessive 44	Enrichment	ADCY1	2.26
55	Acth-independent macronodular adrenal hyperplasia 1	Enrichment	GNAS	2.26
56	Neurodevelopmental disorder with hypotonia and dysmorphic facies	Enrichment	GNB2	2.26
57	Noonan syndrome 13	Enrichment	MAPK1	2.26
58	Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development	Enrichment	PTPA	2.26
59	Pituitary adenoma 3, multiple types	Enrichment	GNAS	2.26
60	Developmental and epileptic encephalopathy 91	Enrichment	PPP3CA	2.26
61	Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual development	Enrichment	PPP3CA	2.26
62	Houge-janssens syndrome 4	Enrichment	PPP2R5C	2.26
63	Intellectual developmental disorder, x-linked 19	Enrichment	RPS6KA3	2.26
64	Houge-janssens syndrome 2	Enrichment	PPP2R1A	2.26
65	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	2.26
66	Thrombocytopenia 4	Enrichment	CYCS	2.26
67	Melorheostosis	Enrichment	MAP2K1	2.26
68	Leopard syndrome 2	Enrichment	RAF1	2.26
69	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	2.26
70	Hypocalcemia, autosomal dominant 2	Enrichment	GNA11	2.26
71	Cowden syndrome 6	Enrichment	AKT1	2.26
72	Immunodeficiency 14b, autosomal recessive	Enrichment	PIK3CD	2.26
73	Charcot-marie-tooth disease, dominant intermediate f	Enrichment	GNB4	2.26
74	Disorders of gnas inactivation	Enrichment	GNAS	2.26
75	Developmental and epileptic encephalopathy 56	Enrichment	YWHAG	2.26
76	Intellectual developmental disorder, autosomal dominant 42	Enrichment	GNB1	2.26
77	Sick sinus syndrome 4	Enrichment	GNB2	2.26
78	Trigonitis	Enrichment	RAF1	2.26
79	Symptomatic form of coffin-lowry syndrome in female carriers	Enrichment	RPS6KA3	2.26
80	Monostotic fibrous dysplasia	Enrichment	GNAS	2.26
81	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.26
82	Ppp2r1a-related neurodevelopmental disorder	Enrichment	PPP2R1A	2.26
83	Phakomatosis cesiomarmorata	Enrichment	GNA11	2.26
84	Kaposiform hemangioendothelioma	Enrichment	GNA14	2.26
85	Mazabraud syndrome	Enrichment	GNAS	2.26
86	Egf-related primary hypomagnesemia with intellectual disability	Enrichment	EGF	2.26
87	Distal 17p13.3 microdeletion syndrome	Enrichment	YWHAE	2.26
88	Macrodactyly	Enrichment	PIK3CA	2.21
89	Metachondromatosis	Enrichment	PTPN11	2.21
90	Acrodysostosis 1 with or without hormone resistance	Enrichment	PRKAR1A	2.21
91	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	2.21
92	Carney complex, type 1	Enrichment	PRKAR1A	2.21
93	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.21
94	Leopard syndrome 1	Enrichment	PTPN11	2.21
95	Cowden syndrome 5	Enrichment	PIK3CA	2.21
96	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.21
97	Short syndrome	Enrichment	PIK3R1	2.21
98	Pyruvate dehydrogenase phosphatase deficiency	Enrichment	PDP1	2.21
99	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	2.21
100	Myxoma, intracardiac	Enrichment	PRKAR1A	2.21
101	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Enrichment	AKT3	2.21
102	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.21
103	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.21
104	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.21
105	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	2.21
106	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.21
107	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	2.21
108	Jansen-de vries syndrome	Enrichment	PPM1D	2.21
109	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.21
110	Hypospadias	Enrichment	PIK3CA	2.21
111	Capillary hemangioma	Enrichment	AKT3	2.21
112	Prkar1b-related neurodegenerative dementia with intermediate filaments	Enrichment	PRKAR1B	2.21
113	Rare venous malformation	Enrichment	PIK3CA	2.21
114	Diaphragmatic eventration	Enrichment	PIK3CA	2.21
115	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.21
116	Rare combined vascular malformation	Enrichment	PIK3CA	2.21
117	Cavernous lymphangioma	Enrichment	PIK3CA	2.21
118	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.21
119	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.21
120	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.21
121	Macrodactyly of toe	Enrichment	PIK3CA	2.21
122	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	2.21
123	Malignant astrocytoma	Enrichment	PTPN11	2.21
124	Fibromatosis, gingival, 1	Enrichment	SOS1	1.96
125	Pseudohypoparathyroidism, type ia	Enrichment	GNAS	1.96
126	Costello syndrome	Enrichment	HRAS	1.96
127	Cutis marmorata telangiectatica congenita	Enrichment	GNA11	1.96
128	Pulmonic stenosis	Enrichment	SOS1	1.96
129	Pseudopseudohypoparathyroidism	Enrichment	GNAS	1.96
130	Roifman-chitayat syndrome	Enrichment	PIK3CD	1.96
131	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	1.96
132	Angioma, tufted	Enrichment	GNA14	1.96
133	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	1.96
134	Intravascular large b-cell lymphoma	Enrichment	BCL2	1.96
135	Autosomal dominant hypocalcemia	Enrichment	GNA11	1.96
136	Pseudohypoparathyroidism	Enrichment	GNAS	1.96
137	Body mass index quantitative trait locus 19	Enrichment	ADCY3	1.96
138	Immune system disease	Enrichment	PIK3CD	1.96
139	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	1.96
140	Houge-janssens syndrome 3	Enrichment	PPP2CA	1.96
141	Growth delay due to insulin-like growth factor type 1 deficiency	Enrichment	IGF1	1.96
142	Acth-independent macronodular adrenal hyperplasia	Enrichment	GNAS	1.96
143	Tafro syndrome	Enrichment	MAP2K2	1.96
144	Cerebral visual impairment	Enrichment	GNB1	1.96
145	Phakomatosis cesioflammea	Enrichment	GNA11	1.96
146	Wooly hair nevus	Enrichment	HRAS	1.96
147	Hydrops fetalis, nonimmune	Enrichment	HRAS, PTPN11	1.95
148	Strabismus	Enrichment	GNB1, PTPN11	1.92
149	Amelogenesis imperfecta, type ig	Enrichment	PRKAR1A	1.91
150	Keratosis, seborrheic	Enrichment	PIK3CA	1.91
151	Noonan syndrome 8	Enrichment	PIK3CA	1.91
152	Marbach-schaaf neurodevelopmental syndrome	Enrichment	PRKAR1B	1.91
153	Werner syndrome	Enrichment	PTPN11	1.91
154	Usher syndrome, type iv	Enrichment	PRKAR1A	1.91
155	Senior-loken syndrome 7	Enrichment	AKT3	1.91
156	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	1.91
157	Acrodysostosis	Enrichment	PRKAR1A	1.91
158	Fibrolamellar carcinoma	Enrichment	PRKACA	1.91
159	Ciliary dyskinesia, primary, 18	Enrichment	PRKAR1B	1.91
160	Bardet-biedl syndrome 16	Enrichment	AKT3	1.91
161	Isolated primary pigmented nodular adrenocortical disease	Enrichment	PRKAR1A	1.91
162	Lung cancer	Enrichment	EGFR, PPP2R1B	1.87
163	Non-immune hydrops fetalis	Enrichment	HRAS, PTPN11	1.80
164	Mccune-albright syndrome	Enrichment	GNAS	1.78
165	Nuchal bleb, familial	Enrichment	SOS1	1.78
166	Langerhans cell histiocytosis	Enrichment	MAP2K1	1.78
167	Neonatal nephrocutaneous inflammatory syndrome	Enrichment	EGFR	1.78
168	Miller-dieker lissencephaly syndrome	Enrichment	YWHAE	1.78
169	Chromosome 17p13.3, centromeric, duplication syndrome	Enrichment	YWHAE	1.78
170	Large congenital melanocytic nevus	Enrichment	HRAS	1.78
171	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	BCL2	1.78
172	Spermatocytoma	Enrichment	HRAS	1.78
173	Cushing syndrome due to bilateral macronodular adrenocortical disease	Enrichment	GNAS	1.78
174	Growth delay due to insulin-like growth factor i resistance	Enrichment	IGF1R	1.78
175	Neonatal inflammatory skin and bowel disease	Enrichment	EGFR	1.78
176	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.73
177	T-cell acute lymphoblastic leukemia	Enrichment	BAX	1.73
178	Tricuspid valve insufficiency	Enrichment	PTPN11	1.73
179	Keratoacanthoma	Enrichment	PIK3CA	1.73
180	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS	1.66
181	Spastic paraplegia 17, autosomal dominant	Enrichment	GNG3	1.66
182	Pseudohypoparathyroidism, type ib	Enrichment	GNAS	1.66
183	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	1.66
184	Lipodystrophy, congenital generalized, type 2	Enrichment	GNG3	1.66
185	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	1.66
186	Epidermolytic nevus	Enrichment	HRAS	1.66
187	Gingival fibromatosis	Enrichment	SOS1	1.66
188	Male infertility due to gonadal dysgenesis or sperm disorder	Enrichment	SOS2	1.66
189	Familial sick sinus syndrome	Enrichment	GNB2	1.66
190	Carney complex variant	Enrichment	PRKAR1A	1.61
191	Arrhythmogenic right ventricular dysplasia, familial, 10	Enrichment	PRKAR1A	1.61
192	Cerebrovascular disease	Enrichment	PIK3CA	1.61
193	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.61
194	2p21 microdeletion syndrome	Enrichment	PPM1B	1.61
195	Capillary malformations, congenital	Enrichment	GNA11	1.56
196	Follicular lymphoma	Enrichment	BCL2	1.56
197	Autosomal thrombocytopenia with normal platelets	Enrichment	CYCS	1.56
198	Endometrial stromal sarcoma	Enrichment	YWHAE	1.56
199	Type 2 diabetes mellitus	Enrichment	AKT2, IRS1	1.56
200	Autism spectrum disorder	Enrichment	GNB1, MAP2K1, PTPN11	1.52
201	Lymphoma	Enrichment	PTPN11	1.51
202	Body mass index quantitative trait locus 11	Enrichment	ADCY3, GNAS	1.51
203	Melanoma, uveal	Enrichment	GNA11	1.49
204	Kidney clear cell sarcoma	Enrichment	YWHAE	1.49
205	Thrombocytopenia	Enrichment	CYCS, PTPN11	1.45
206	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA	1.44
207	Hemihyperplasia, isolated	Enrichment	PIK3CA	1.44
208	Patent ductus arteriosus	Enrichment	PTPN11	1.44
209	Adrenocortical carcinoma	Enrichment	PRKAR1A	1.44
210	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS	1.42
211	Squamous cell carcinoma, head and neck	Enrichment	EGFR	1.42
212	Brachydactyly	Enrichment	GNAS	1.42
213	Pilomyxoid astrocytoma	Enrichment	RAF1	1.42
214	Follicular thyroid carcinoma	Enrichment	HRAS	1.42
215	Undetermined early-onset epileptic encephalopathy	Enrichment	PPP3CA, YWHAG	1.42
216	Hypertelorism	Enrichment	PIK3CA, RPS6KA3	1.39
217	Gallbladder cancer	Enrichment	PIK3CA	1.37
218	Megacolon	Enrichment	AKT3	1.37
219	Overgrowth syndrome	Enrichment	PIK3R1	1.37
220	Gastroesophageal reflux	Enrichment	RPS6KA3	1.36
221	Spastic paraplegia 4, autosomal dominant	Enrichment	GNAS	1.36
222	Orthostatic intolerance	Enrichment	RPS6KA3	1.36
223	Hypothyroidism	Enrichment	GNB1	1.36
224	Inherited cancer-predisposing syndrome	Enrichment	EGFR, PRKAR1A, PTPN11	1.31
225	Adult hepatocellular carcinoma	Enrichment	EGF	1.31
226	Primary hyperaldosteronism	Enrichment	GNAS	1.31
227	Ventricular septal defect	Enrichment	RPS6KA3	1.31
228	Leukemia, acute lymphoblastic	Enrichment	GNB1	1.23
229	Myelodysplastic syndrome	Enrichment	GNB1	1.23
230	Polymicrogyria	Enrichment	AKT3	1.22
231	Pectus excavatum	Enrichment	PTPN11	1.18
232	Aortic valve disease 1	Enrichment	SOS1	1.16
233	Epicanthus	Enrichment	PTPN11	1.14
234	Juvenile myelomonocytic leukemia	Enrichment	PTPN11	1.14
235	Congenital long qt syndrome	Enrichment	PTPN11	1.14
236	Lung cancer susceptibility 3	Enrichment	EGFR	1.13
237	46,xy partial gonadal dysgenesis	Enrichment	SOS1	1.13
238	Acute promyelocytic leukemia	Enrichment	PRKAR1A	1.11
239	Rhabdomyosarcoma	Enrichment	HRAS	1.07
240	Gliosarcoma	Enrichment	EGFR	1.07
241	Lynch syndrome	Enrichment	PIK3CA	1.05
242	Hypertension, essential	Enrichment	GNB3	1.05
243	Cleft palate, isolated	Enrichment	GNB1	1.05
244	Giant cell glioblastoma	Enrichment	EGFR	1.05
245	Heart, malformation of	Enrichment	MAPK1	1.02
246	Arteriovenous malformations of the brain	Enrichment	EGFR	1.00
247	Patent foramen ovale	Enrichment	PTPN11	0.98
248	Attention deficit-hyperactivity disorder	Enrichment	GNB5	0.94
249	Congenital stationary night blindness	Enrichment	GNB3	0.92
250	Endometrial cancer	Enrichment	PIK3CA	0.91
251	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	0.90
252	Hepatocellular carcinoma	Enrichment	PIK3CA	0.89
253	Scoliosis	Enrichment	PTPN11	0.86
254	Differentiated thyroid carcinoma	Enrichment	HRAS	0.83
255	Complex neurodevelopmental disorder	Enrichment	GNB2, PPP2CA	0.82
256	Prostate cancer	Enrichment	PIK3CA	0.78
257	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.78
258	Long qt syndrome 1	Enrichment	PTPN11	0.77
259	Left ventricular noncompaction	Enrichment	RAF1	0.75
260	Dystonia	Enrichment	GNB1	0.75
261	Non-syndromic x-linked intellectual disability	Enrichment	RPS6KA3	0.74
262	Cerebral palsy	Enrichment	GNB1	0.71
263	Gastric cancer	Enrichment	PIK3CA	0.63
264	Hypertrophic cardiomyopathy	Enrichment	PTPN11	0.63
265	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	0.59
266	Myeloma, multiple	Enrichment	PIK3R2	0.53
267	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	PTPN11	0.53
268	Dilated cardiomyopathy	Enrichment	RAF1	0.44
269	Primary ciliary dyskinesia	Enrichment	PRKAR1B	0.42
270	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	ADCY1	0.41
271	Congenital nervous system abnormality	Enrichment	GNB5	0.35
272	Nervous system disease	Enrichment	GNB5	0.35

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Apoptosis and survival BAD phosphorylation

Pathway Network for Apoptosis and survival BAD phosphorylation

Member Pathways for Apoptosis and survival BAD phosphorylation

Pathways in the Apoptosis and survival BAD phosphorylation SuperPath

Associated Genes for Apoptosis and survival BAD phosphorylation

Associated Disorders for Apoptosis and survival BAD phosphorylation

Disorders associated with Apoptosis and survival BAD phosphorylation SuperPath

STRING Interaction Network for Apoptosis and survival BAD phosphorylation

Sources for Apoptosis and survival BAD phosphorylation