Apoptotic Pathways in Synovial Fibroblasts

Pathway network for the Apoptotic Pathways in Synovial Fibroblasts SuperPath

Sources:

QIAGEN

Pathways in the Apoptotic Pathways in Synovial Fibroblasts SuperPath

#	Name	Source	Genes
1	Apoptotic Pathways in Synovial Fibroblasts	QIAGEN	AKT1 ANGPTL6 AREG BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC CASP8 CCN2 CFLAR CLEC11A CLEC14A CRIPTO CXCL12 DRC4 EGF EGFR FADD FAS FASLG FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLG1 GMFG GNRH1 GNRH2 GPC6 HBEGF HDGF HGF IGF1 IGF1R IGF2 IGF2-AS IGF2R IL2 IL2RA IL3 IL6 IL9 KDR KIT KITLG KLF10 LEFTY1 LEFTY2 LHB LTA LTBP1 LTBP2 LTBP3 LTBP4 MDK MET NFKB1 NGF NGFR NRG1 NRG2 NRG3 NRP1 NRP2 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGFR OGN PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLPP3 PPBP PROK1 PSIP1 PTN SEMA3A SEMA4B SEMA4G SEMA5A SPON1 TBRG1 TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TNF TNFRSF1A TNFRSF1B TP53 TYMP UTS2 VEGFB VEGFC VEGFD XIAP (see all 159) (see less)
2	Rap1 Pathway	QIAGEN	ANGPTL6 AREG ARHGEF1 ARHGEF10 ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF2 ARHGEF3 ARHGEF4 ARHGEF5 ARHGEF6 ARHGEF7 ARHGEF9 BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BRAF BTC CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 CBL CCN2 CD247 CD3E CLEC11A CRIPTO CRKL CXCL12 DRC4 EGF EGFR EPOR ERBB2 ERBB3 ERBB4 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FYB1 FYN GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GMFG GNA11 GNA12 GNA13 GNA14 GNA15 GNAL GNAS GNB1 GNB2 GNB3 GNB4 GNB5 GNG2 GNG3 GNG4 GNRH1 GNRH2 GPC6 GPR119 GRAP2 GRB2 HDGF HGF HRAS IGF1 IGF1R IGF2 IGF2-AS IL2 IL3 IL6 IL9 INSR ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 ITPR1 ITPR2 ITPR3 KITLG KLF10 KRAS LAT LCK LCP2 LEFTY1 LEFTY2 LHB LIFR LTBP1 LTBP2 LTBP3 LTBP4 MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAPK1 MAPK12 MAPK3 MAPK6 MAPK7 MCF2L MDK MRAS NET1 NGF NRAS NRG1 NRG2 NRG3 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGN P2RY13 PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PLCE1 PLCG1 PLPP3 PPBP PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PROK1 PSIP1 PTN RAF1 RAP1A RAP1B RAP1GAP RAPGEF1 RASGRP1 RASGRP2 RRAS RRAS2 SEMA3A SEMA4B SEMA4G SEMA5A SOS1 SOS2 SPON1 TBRG1 TGFA TGFB1 TGFB2 TGFB3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TYMP UTS2 VEGFB VEGFC VEGFD ZAP70 (see all 266) (see less)
3	Actin-Based Motility by Rho Family GTPases	QIAGEN	ACTA1 ACTA2 ACTB ACTG1 ACTG2 ACTR2 ACTR3 ANGPTL6 AREG ARHGDIA ARHGDIB BAIAP2 BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC CCN2 CDC42 CFL1 CFL2 CLEC11A CLEC14A CRIPTO CXCL12 DIRAS3 DRC4 EGF EGFR FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLG1 GMFG GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAT1 GNAT2 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GNRH1 GNRH2 GPC6 GPR119 GSN HBEGF HDGF HGF IGF1 IGF1R IGF2 IGF2-AS IGF2R IL2 IL2RA IL3 IL6 IL9 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 KDR KIT KITLG KLF10 LEFTY1 LEFTY2 LHB LIMK1 LIMK2 LTBP1 LTBP2 LTBP3 LTBP4 MDK MET MYL9 MYLK NGF NGFR NRG1 NRG2 NRG3 NRP1 NRP2 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGFR OGN P2RY13 PAK1 PAK2 PAK3 PAK4 PAK5 PAK6 PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PFN1 PFN2 PGF PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PLPP3 PPBP PPP1CB PPP1R12A PPP1R12B PROK1 PSIP1 PTN RAC1 RAC2 RAC3 RHOA RHOB RHOC RHOD RHOG RHOH RHOJ RHOQ RND2 RND3 ROCK1 ROCK2 SEMA3A SEMA4B SEMA4G SEMA5A SPON1 TBRG1 TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TYMP UTS2 VEGFB VEGFC VEGFD WASF1 WASL (see all 253) (see less)
4	Rac1 Pathway	QIAGEN	ABI2 ACTR2 ACTR3 ANGPTL6 ANK1 AREG ARFIP2 ARHGEF6 BAIAP2 BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BRK1 BTC CCN2 CD44 CDC42 CDK5R1 CFL1 CFL2 CLEC11A CLEC14A CRIPTO CXCL12 CYFIP1 CYFIP2 DRC4 EGF EGFR ELK1 ELK4 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLG1 GMFG GNRH1 GNRH2 GPC6 HBEGF HDGF HGF HRAS IGF1 IGF1R IGF2 IGF2-AS IGF2R IL2 IL2RA IL3 IL6 IL9 IQGAP1 IQGAP2 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 JUN KDR KIT KITLG KLF10 KRAS LEFTY1 LEFTY2 LHB LIMK1 LIMK2 LTBP1 LTBP2 LTBP3 LTBP4 MAP2K1 MAP2K2 MAP2K4 MAP2K7 MAP3K11 MAPK1 MAPK3 MAPK8 MCF2L MDK MET MRAS NCF2 NCKAP1 NFKB1 NGF NGFR NOX1 NOX3 NOX4 NOX5 NRAS NRG1 NRG2 NRG3 NRP1 NRP2 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGFR OGN PAK1 PAK2 PAK3 PAK4 PAK5 PAK6 PARD3 PARD6A PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PLD1 PLPP3 PPBP PRKCI PRKCZ PROK1 PSIP1 PTK2 PTK2B PTN RAC1 RACGAP1 RAF1 RHOA RPS6KB1 RRAS RRAS2 SEMA3A SEMA4B SEMA4G SEMA5A SH3RF1 SPON1 TBRG1 TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR3 THPO TIAM1 TIMP1 TIMP2 TIMP3 TIMP4 TYMP UTS2 VEGFB VEGFC VEGFD WASF1 (see all 243) (see less)
5	eIF2 Pathway	QIAGEN	AGO1 AGO2 AKT1 ANGPTL6 ARAF AREG BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BRAF BTC CCN2 CLEC11A CLEC14A CRIPTO CXCL12 DRC4 EGF EGFR EIF1AX EIF1AY EIF2A EIF2AK1 EIF2AK2 EIF2AK3 EIF2AK4 EIF2B1 EIF2B2 EIF2B3 EIF2B4 EIF2B5 EIF2S1 EIF2S2 EIF2S3 EIF3A EIF3B EIF3C EIF3D EIF3E EIF3F EIF3G EIF3H EIF3I EIF3J EIF4A1 EIF4A2 EIF4E EIF4G1 EIF4G2 EIF4G3 EIF5 EIF5A EIF5A2 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLG1 GMFG GNRH1 GNRH2 GPC6 GRB2 GSK3B HBEGF HDGF HGF HRAS IGF1 IGF1R IGF2 IGF2-AS IGF2R IL2 IL2RA IL3 IL6 IL9 INS INSR KDR KIT KITLG KLF10 KRAS LEFTY1 LEFTY2 LHB LTBP1 LTBP2 LTBP3 LTBP4 MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAPK1 MAPK12 MAPK3 MAPK6 MAPK7 MDK MET MRAS NGF NGFR NRAS NRG1 NRG2 NRG3 NRP1 NRP2 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGFR OGN PABPC1 PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PDPK1 PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLPP3 PPBP PPP1R10 PPP1R11 PPP1R12A PPP1R12B PPP1R12C PPP1R13B PPP1R14A PPP1R14B PPP1R15A PPP1R16A PPP1R1A PPP1R1B PPP1R2 PPP1R3A PPP1R3B PPP1R3C PPP1R3D PPP1R3F PPP1R7 PPP1R8 PPP1R9A PPP1R9B PROK1 PSIP1 PTN RAF1 RRAS RRAS2 SEMA3A SEMA4B SEMA4G SEMA5A SOS1 SOS2 SPON1 TBRG1 TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TP53BP2 TYMP UTS2 VEGFB VEGFC VEGFD (see all 234) (see less)
6	Cellular Apoptosis Pathway	QIAGEN	AIFM1 AKT1 ANGPTL6 APAF1 AREG ATM BAD BAK1 BAX BBC3 BCL2 BCL2L1 BCL2L11 BDNF BID BIRC2 BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC CASP3 CASP7 CASP8 CASP9 CCN2 CDKN2A CFLAR CHEK2 CHUK CLEC11A CLEC14A CRIPTO CXCL12 CYCS DAPK3 DAXX DFFA DIABLO DRC4 EGF EGFR ENDOG FADD FAS FASLG FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLG1 GMFG GNRH1 GNRH2 GPC6 HBEGF HDGF HGF HTRA2 IGF1 IGF1R IGF2 IGF2-AS IGF2R IKBKB IKBKE IKBKG IL2 IL2RA IL3 IL6 IL9 KDR KIT KITLG KLF10 LEFTY1 LEFTY2 LHB LTBP1 LTBP2 LTBP3 LTBP4 MDK MDM2 MET NFKB1 NFKBIA NFKBIB NFKBIE NGF NGFR NRG1 NRG2 NRG3 NRP1 NRP2 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGFR OGN PARP1 PARP10 PARP11 PARP14 PARP15 PARP16 PARP3 PARP4 PARP8 PAWR PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLPP3 PMAIP1 PML PPBP PPID PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD3 PROK1 PRPS1 PSIP1 PTN RIPK1 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KA5 RPS6KA6 SEMA3A SEMA4B SEMA4G SEMA5A SLC25A4 SLC25A5 SLC25A6 SPON1 TBRG1 TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TNF TNFRSF10A TNFRSF1A TNFSF10 TNFSF12 TP53 TP53AIP1 TRADD TRAF2 TSPO TYMP UTS2 VDAC1 VDAC1P4 VDAC2 VDAC3 VEGFB VEGFC VEGFD (see all 234) (see less)
7	Nuclear Receptor Activation by Vitamin-A	QIAGEN	ANGPTL6 AREG ATF4 BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC CARM1 CCN2 CLEC11A CLEC14A CRABP2 CREB1 CREB3 CREB3L4 CREBBP CRIPTO CXCL12 DRC4 EGF EGFR EP300 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLG1 GMFG GNRH1 GNRH2 GPC6 GRIP1 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 H3-3A H3-3B H3-4 H3C1 H3C10 H3C11 H3C12 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H4C1 H4C11 H4C12 H4C13 H4C14 H4C2 H4C3 H4C4 H4C5 H4C6 H4C7 H4C8 H4C9 HAT1 HBEGF HDGF HGF IGF1 IGF1R IGF2 IGF2-AS IGF2R IL2 IL2RA IL3 IL6 IL9 KAT2B KDR KIT KITLG KLF10 LEFTY1 LEFTY2 LHB LTBP1 LTBP2 LTBP3 LTBP4 MDK MET NCOA1 NCOA3 NGF NGFR NRG1 NRG2 NRG3 NRP1 NRP2 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGFR OGN PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PLPP3 POLR2A POLR2B POLR2C PPBP PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRMT1 PROK1 PSIP1 PTN RARA RARB RARG RBP5 RXRA RXRB RXRG SEMA3A SEMA4B SEMA4G SEMA5A SPON1 TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1A TAF1B TAF1C TAF1L TAF2 TAF4 TAF5 TAF5L TAF6 TAF6L TAF7 TAF7L TAF9 TAF9B TBP TBRG1 TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TYMP UTS2 VEGFB VEGFC VEGFD (see all 229) (see less)
8	PPAR Pathway	QIAGEN	ADCY1 ADCY2 ADCY3 AKT1 ANGPTL6 AREG BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC CCN2 CLEC11A CLEC14A CREBBP CRIPTO CXCL12 DRC4 EGF EGFR EP300 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLG1 GMFG GNAS GNRH1 GNRH2 GPC6 GPR119 GRB2 HBEGF HDGF HGF HRAS IGF1 IGF1R IGF2 IGF2-AS IGF2R IL2 IL2RA IL3 IL6 IL9 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 KDR KIT KITLG KLF10 KRAS LEFTY1 LEFTY2 LHB LTA LTBP1 LTBP2 LTBP3 LTBP4 MAP2K1 MAP2K3 MAP2K6 MAP3K7 MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MDK MET MRAS NCOA1 NGF NGFR NRAS NRG1 NRG2 NRG3 NRP1 NRP2 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGFR OGN P2RY13 PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLPP3 PPARA PPARD PPARG PPBP PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PROK1 PSIP1 PTGIR PTN RAF1 RRAS RRAS2 RXRA RXRB RXRG SEMA3A SEMA4B SEMA4G SEMA5A SOS1 SOS2 SPON1 TBRG1 TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TNF TNFRSF1A TNFRSF1B TYMP UTS2 VEGFB VEGFC VEGFD (see all 220) (see less)
9	ERK5 Signaling	QIAGEN	AKT1 ANGPTL6 AREG ATF4 BAD BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC CCN2 CLEC11A CLEC14A CREB1 CREB3 CREB3L4 CRIPTO CTF1 CXCL12 DRC4 EGF EGFR ELK4 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 FOS FOSL1 FOXO3 GAB1 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLG1 GMFG GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAT1 GNAT2 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GNRH1 GNRH2 GPC6 HBEGF HDGF HGF HRAS IGF1 IGF1R IGF2 IGF2-AS IGF2R IL2 IL2RA IL3 IL6 IL6ST IL9 KDR KIT KITLG KLF10 KRAS LEFTY1 LEFTY2 LHB LIF LTBP1 LTBP2 LTBP3 LTBP4 MAP2K5 MAP3K2 MAP3K3 MAP3K8 MAPK7 MDK MEF2A MEF2C MEF2D MET MRAS MYC NGF NGFR NRAS NRG1 NRG2 NRG3 NRP1 NRP2 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGFR OGN PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PLPP3 PPBP PROK1 PSIP1 PTN RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KA6 RRAS RRAS2 SEMA3A SEMA4B SEMA4G SEMA5A SH2D2A SPON1 SRC TBRG1 TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TYMP UTS2 VEGFB VEGFC VEGFD WNK1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 215) (see less)
10	Mitochondrial Apoptosis	QIAGEN	AIFM1 AKT1 ANGPTL6 APAF1 AREG ATM BAD BAK1 BAX BBC3 BCL2 BCL2L1 BCL2L11 BDNF BID BIRC2 BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC CASP12 CASP3 CASP8 CASP9 CCN2 CDKN2A CHEK2 CLEC11A CLEC14A CRIPTO CXCL12 CYCS DIABLO DRC4 EGF EGFR ENDOG FADD FAS FASLG FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLG1 GMFG GNRH1 GNRH2 GPC6 HBEGF HDGF HGF HTRA2 IGF1 IGF1R IGF2 IGF2-AS IGF2R IL2 IL2RA IL3 IL6 IL9 KDR KIT KITLG KLF10 LEFTY1 LEFTY2 LHB LTBP1 LTBP2 LTBP3 LTBP4 MDK MDM2 MET NGF NGFR NRG1 NRG2 NRG3 NRP1 NRP2 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGFR OGN PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLPP3 PMAIP1 PPBP PPID PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD3 PROK1 PRPS1 PSIP1 PTN RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KA5 RPS6KA6 SEMA3A SEMA4B SEMA4G SEMA5A SLC25A4 SLC25A5 SLC25A6 SPON1 TBRG1 TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TP53 TP53AIP1 TSPO TYMP UTS2 VDAC1 VDAC1P4 VDAC2 VDAC3 VEGFB VEGFC VEGFD (see all 203) (see less)
11	DHA Signaling	QIAGEN	AKT1 AKT2 AKT3 ALOX15 ANGPTL6 APAF1 APP AREG BAD BAX BCL2 BCL2A1 BCL2L1 BDNF BID BIK BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC CASP1 CASP10 CASP2 CASP3 CASP4 CASP5 CASP6 CASP7 CASP8 CASP9 CCN2 CLEC11A CRIPTO CXCL12 CYCS DRC4 EGF EGFR FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 FOXO1 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLG1 GMFG GNRH1 GNRH2 GPC6 GSK3A GSK3B HBEGF HDGF HGF IDE IGF1 IGF1R IGF2 IGF2-AS IGF2R IL1B IL2 IL2RA IL3 IL6 IL9 KDR KIT KITLG KLF10 LEFTY1 LEFTY2 LHB LTBP1 LTBP2 LTBP3 LTBP4 MAPT MDK MET NGF NGFR NRG1 NRG2 NRG3 NRP1 NRP2 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGFR OGN PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PDPK1 PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLA2G10 PLA2G12A PLA2G12B PLA2G1B PLA2G2A PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4C PLA2G5 PLA2G6 PLA2G7 PLPP3 PPBP PROK1 PSIP1 PTN SEMA3A SEMA4B SEMA4G SEMA5A SERPINF1 SPON1 TBRG1 TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TYMP UTS2 VEGFB VEGFC VEGFD YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 197) (see less)
12	Glioma Invasiveness	QIAGEN	ANGPTL6 AREG BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC CCN2 CD44 CLEC11A CRIPTO CXCL12 DIRAS3 DRC4 EGF F2R FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GMFG GNRH1 GNRH2 GPC6 HDGF HGF HMMR HRAS IGF1 IGF2 IGF2-AS IL2 IL3 IL6 IL9 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 KITLG KLF10 KRAS LEFTY1 LEFTY2 LHB LTBP1 LTBP2 LTBP3 LTBP4 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK4 MAPK6 MAPK7 MAPK8 MAPK9 MDK MMP2 MMP9 MRAS NGF NRAS NRG1 NRG2 NRG3 NTF3 NTF4 NUDT6 OGN PDGFA PDGFB PDGFC PDGFD PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLAU PLAUR PLG PLPP3 PPBP PROK1 PSIP1 PTK2 PTK2B PTN RHOA RHOB RHOC RHOD RHOG RHOH RND2 RND3 RRAS RRAS2 SEMA3A SEMA4B SEMA4G SEMA5A SPON1 TBRG1 TGFA TGFB1 TGFB2 TGFB3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TYMP UTS2 VEGFB VEGFC VEGFD VTN (see all 183) (see less)
13	Telomerase Components in Cell Signaling	QIAGEN	ABL1 AKT1 ANGPTL6 AREG ATM BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC CCN2 CLEC11A CLEC14A CRIPTO CXCL12 DKC1 DRC4 EGFR FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLG1 GMFG GNRH1 GNRH2 GPC6 HBEGF HDGF HGF HSP90AA1 IGF1 IGF1R IGF2 IGF2-AS IGF2R IL2 IL2RA IL3 IL6 IL9 KDR KIT KITLG KLF10 KRAS LEFTY1 LEFTY2 LHB LTBP1 LTBP2 LTBP3 LTBP4 MDK MET MYC NGF NGFR NRG1 NRG2 NRG3 NRP1 NRP2 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGFR OGN PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PLPP3 POLR2A POLR2B POLR2C POT1 PPBP PPP2R1A PPP2R1B PPP2R2A PPP2R2B PPP2R2C PPP2R3A PPP2R3B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PROK1 PSIP1 PTN PTPA RB1 SEMA3A SEMA4B SEMA4G SEMA5A SPON1 TBRG1 TEP1 TERF1 TERF2 TERT TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TINF2 TNKS TNKS2 TP53 TYMP UTS2 VEGFB VEGFC VEGFD (see all 179) (see less)
14	p53 Mediated Apoptosis	QIAGEN	AKT1 AKT2 AKT3 ANGPTL6 APAF1 AREG ATM ATR BAX BBC3 BCL2 BDNF BID BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC CASP3 CASP6 CASP8 CASP9 CCN2 CHEK1 CHEK2 CLEC11A CLEC14A CRIPTO CXCL12 CYCS DRC4 EGF EGFR FAS FASLG FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GLG1 GMFG GNRH1 GNRH2 GPC6 HBEGF HDGF HGF IGF1 IGF1R IGF2 IGF2-AS IGF2R IL2 IL2RA IL3 IL6 IL9 KDR KIT KITLG KLF10 LEFTY1 LEFTY2 LHB LTBP1 LTBP2 LTBP3 LTBP4 MDK MDM2 MET NGF NGFR NRG1 NRG2 NRG3 NRP1 NRP2 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGFR OGN PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PERP PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLPP3 PMAIP1 PPBP PROK1 PSIP1 PTEN PTN SEMA3A SEMA4B SEMA4G SEMA5A SPON1 TBRG1 TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TNFRSF10B TNFSF10 TP53 TP53AIP1 TYMP UTS2 VEGFB VEGFC VEGFD (see all 173) (see less)

Gene overlap in member pathways for Apoptotic Pathways in Synovial Fibroblasts SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ANGPTL6	Angiopoietin Like 6	Protein Coding	14
2	AREG	Amphiregulin	Protein Coding	14
3	BDNF	Brain Derived Neurotrophic Factor	Protein Coding	14
4	BMP1	Bone Morphogenetic Protein 1	Protein Coding	14
5	BMP10	Bone Morphogenetic Protein 10	Protein Coding	14
6	BMP2	Bone Morphogenetic Protein 2	Protein Coding	14
7	BMP3	Bone Morphogenetic Protein 3	Protein Coding	14
8	BMP4	Bone Morphogenetic Protein 4	Protein Coding	14
9	BMP5	Bone Morphogenetic Protein 5	Protein Coding	14
10	BMP6	Bone Morphogenetic Protein 6	Protein Coding	14
11	BMP7	Bone Morphogenetic Protein 7	Protein Coding	14
12	BMP8A	Bone Morphogenetic Protein 8a	Protein Coding	14
13	BTC	Betacellulin	Protein Coding	14
14	CCN2	Cellular Communication Network Factor 2	Protein Coding	14
15	CXCL12	C-X-C Motif Chemokine Ligand 12	Protein Coding	14
16	LEFTY2	Left-Right Determination Factor 2	Protein Coding	14
17	TYMP	Thymidine Phosphorylase	Protein Coding	14
18	FGF1	Fibroblast Growth Factor 1	Protein Coding	14
19	FGF10	Fibroblast Growth Factor 10	Protein Coding	14
20	FGF11	Fibroblast Growth Factor 11	Protein Coding	14
21	FGF12	Fibroblast Growth Factor 12	Protein Coding	14
22	FGF13	Fibroblast Growth Factor 13	Protein Coding	14
23	FGF14	Fibroblast Growth Factor 14	Protein Coding	14
24	FGF16	Fibroblast Growth Factor 16	Protein Coding	14
25	FGF17	Fibroblast Growth Factor 17	Protein Coding	14
26	FGF18	Fibroblast Growth Factor 18	Protein Coding	14
27	FGF19	Fibroblast Growth Factor 19	Protein Coding	14
28	FGF2	Fibroblast Growth Factor 2	Protein Coding	14
29	FGF20	Fibroblast Growth Factor 20	Protein Coding	14
30	FGF21	Fibroblast Growth Factor 21	Protein Coding	14
31	FGF22	Fibroblast Growth Factor 22	Protein Coding	14
32	FGF23	Fibroblast Growth Factor 23	Protein Coding	14
33	FGF4	Fibroblast Growth Factor 4	Protein Coding	14
34	FGF5	Fibroblast Growth Factor 5	Protein Coding	14
35	FGF6	Fibroblast Growth Factor 6	Protein Coding	14
36	FGF7	Fibroblast Growth Factor 7	Protein Coding	14
37	FGF8	Fibroblast Growth Factor 8	Protein Coding	14
38	VEGFD	Vascular Endothelial Growth Factor D	Protein Coding	14
39	GAS1	Growth Arrest Specific 1	Protein Coding	14
40	GAS2	Growth Arrest Specific 2	Protein Coding	14
41	GAS6	Growth Arrest Specific 6	Protein Coding	14
42	DRC4	Dynein Regulatory Complex Subunit 4	Protein Coding	14
43	GDF10	Growth Differentiation Factor 10	Protein Coding	14
44	GDF2	Growth Differentiation Factor 2	Protein Coding	14
45	GDF5	Growth Differentiation Factor 5	Protein Coding	14
46	GDF6	Growth Differentiation Factor 6	Protein Coding	14
47	GDF9	Growth Differentiation Factor 9	Protein Coding	14
48	GFER	Growth Factor, Augmenter Of Liver Regeneration	Protein Coding	14
49	GH1	Growth Hormone 1	Protein Coding	14
50	GH2	Growth Hormone 2	Protein Coding	14
51	GHRH	Growth Hormone Releasing Hormone	Protein Coding	14
52	GMFG	Glia Maturation Factor Gamma	Protein Coding	14
53	GNRH1	Gonadotropin Releasing Hormone 1	Protein Coding	14
54	GNRH2	Gonadotropin Releasing Hormone 2	Protein Coding	14
55	GPC6	Glypican 6	Protein Coding	14
56	HDGF	Heparin Binding Growth Factor	Protein Coding	14
57	HGF	Hepatocyte Growth Factor	Protein Coding	14
58	IGF1	Insulin Like Growth Factor 1	Protein Coding	14
59	IGF2	Insulin Like Growth Factor 2	Protein Coding	14
60	IGF2-AS	IGF2 Antisense RNA	RNA Gene	14
61	IL2	Interleukin 2	Protein Coding	14
62	IL3	Interleukin 3	Protein Coding	14
63	IL6	Interleukin 6	Protein Coding	14
64	IL9	Interleukin 9	Protein Coding	14
65	KITLG	KIT Ligand	Protein Coding	14
66	LEFTY1	Left-Right Determination Factor 1	Protein Coding	14
67	LHB	Luteinizing Hormone Subunit Beta	Protein Coding	14
68	LTBP1	Latent Transforming Growth Factor Beta Binding Protein 1	Protein Coding	14
69	LTBP2	Latent Transforming Growth Factor Beta Binding Protein 2	Protein Coding	14
70	LTBP3	Latent Transforming Growth Factor Beta Binding Protein 3	Protein Coding	14
71	LTBP4	Latent Transforming Growth Factor Beta Binding Protein 4	Protein Coding	14
72	MDK	Midkine	Protein Coding	14
73	NGF	Nerve Growth Factor	Protein Coding	14
74	NRG1	Neuregulin 1	Protein Coding	14
75	NRG2	Neuregulin 2	Protein Coding	14
76	NRG3	Neuregulin 3	Protein Coding	14
77	NTF3	Neurotrophin 3	Protein Coding	14
78	NTF4	Neurotrophin 4	Protein Coding	14
79	NUDT6	Nudix Hydrolase 6	Protein Coding	14
80	OGN	Osteoglycin	Protein Coding	14
81	PDGFA	Platelet Derived Growth Factor Subunit A	Protein Coding	14
82	PDGFB	Platelet Derived Growth Factor Subunit B	Protein Coding	14
83	PDGFC	Platelet Derived Growth Factor C	Protein Coding	14
84	PENK	Proenkephalin	Protein Coding	14
85	PGF	Placental Growth Factor	Protein Coding	14
86	GDF15	Growth Differentiation Factor 15	Protein Coding	14
87	PLPP3	Phospholipid Phosphatase 3	Protein Coding	14
88	PPBP	Pro-Platelet Basic Protein	Protein Coding	14
89	PROK1	Prokineticin 1	Protein Coding	14
90	PSIP1	PC4 And SRSF1 Interacting Protein 1	Protein Coding	14
91	PTN	Pleiotrophin	Protein Coding	14
92	PDGFD	Platelet Derived Growth Factor D	Protein Coding	14
93	CLEC11A	C-Type Lectin Domain Containing 11A	Protein Coding	14
94	SEMA3A	Semaphorin 3A	Protein Coding	14
95	SEMA4B	Semaphorin 4B	Protein Coding	14
96	SEMA4G	Semaphorin 4G	Protein Coding	14
97	SEMA5A	Semaphorin 5A	Protein Coding	14
98	SPON1	Spondin 1	Protein Coding	14
99	TBRG1	Transforming Growth Factor Beta Regulator 1	Protein Coding	14
100	CRIPTO	Cripto, EGF-CFC Family Member	Protein Coding	14
101	TGFA	Transforming Growth Factor Alpha	Protein Coding	14
102	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	14
103	TGFB2	Transforming Growth Factor Beta 2	Protein Coding	14
104	TGFB3	Transforming Growth Factor Beta 3	Protein Coding	14
105	THPO	Thrombopoietin	Protein Coding	14
106	KLF10	KLF Transcription Factor 10	Protein Coding	14
107	TIMP1	TIMP Metallopeptidase Inhibitor 1	Protein Coding	14
108	TIMP2	TIMP Metallopeptidase Inhibitor 2	Protein Coding	14
109	TIMP3	TIMP Metallopeptidase Inhibitor 3	Protein Coding	14
110	TIMP4	TIMP Metallopeptidase Inhibitor 4	Protein Coding	14
111	UTS2	Urotensin 2	Protein Coding	14
112	VEGFB	Vascular Endothelial Growth Factor B	Protein Coding	14
113	VEGFC	Vascular Endothelial Growth Factor C	Protein Coding	14
114	EGF	Epidermal Growth Factor	Protein Coding	13
115	EGFR	Epidermal Growth Factor Receptor	Protein Coding	13
116	FGFR1	Fibroblast Growth Factor Receptor 1	Protein Coding	13
117	FGFR2	Fibroblast Growth Factor Receptor 2	Protein Coding	13
118	FGFR3	Fibroblast Growth Factor Receptor 3	Protein Coding	13
119	FGFR4	Fibroblast Growth Factor Receptor 4	Protein Coding	13
120	IGF1R	Insulin Like Growth Factor 1 Receptor	Protein Coding	13
121	NTRK1	Neurotrophic Receptor Tyrosine Kinase 1	Protein Coding	13
122	NTRK2	Neurotrophic Receptor Tyrosine Kinase 2	Protein Coding	13
123	NTRK3	Neurotrophic Receptor Tyrosine Kinase 3	Protein Coding	13
124	PDGFRA	Platelet Derived Growth Factor Receptor Alpha	Protein Coding	13
125	PDGFRB	Platelet Derived Growth Factor Receptor Beta	Protein Coding	13
126	HBEGF	Heparin Binding EGF Like Growth Factor	Protein Coding	12
127	FLT1	Fms Related Receptor Tyrosine Kinase 1	Protein Coding	12
128	FLT4	Fms Related Receptor Tyrosine Kinase 4	Protein Coding	12
129	GLG1	Golgi Glycoprotein 1	Protein Coding	12
130	IGF2R	Insulin Like Growth Factor 2 Receptor	Protein Coding	12
131	IL2RA	Interleukin 2 Receptor Subunit Alpha	Protein Coding	12
132	KDR	Kinase Insert Domain Receptor	Protein Coding	12
133	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	12
134	MET	MET Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	12
135	NGFR	Nerve Growth Factor Receptor	Protein Coding	12
136	NRP1	Neuropilin 1	Protein Coding	12
137	NRP2	Neuropilin 2	Protein Coding	12
138	OGFR	Opioid Growth Factor Receptor	Protein Coding	12
139	TGFBR1	Transforming Growth Factor Beta Receptor 1	Protein Coding	12
140	TGFBR3	Transforming Growth Factor Beta Receptor 3	Protein Coding	12
141	CLEC14A	C-Type Lectin Domain Containing 14A	Protein Coding	11
142	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	9
143	PIK3R5	Phosphoinositide-3-Kinase Regulatory Subunit 5	Protein Coding	9
144	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	9
145	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	9
146	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	9
147	PIK3R4	Phosphoinositide-3-Kinase Regulatory Subunit 4	Protein Coding	9
148	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	7
149	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	6
150	MRAS	Muscle RAS Oncogene Homolog	Protein Coding	6
151	NRAS	NRAS Proto-Oncogene, GTPase	Protein Coding	6
152	RRAS	RAS Related	Protein Coding	6
153	RRAS2	RAS Related 2	Protein Coding	6
154	CASP8	Caspase 8	Protein Coding	5
155	TP53	Tumor Protein P53	Protein Coding	5
156	ITGA1	Integrin Subunit Alpha 1	Protein Coding	5
157	ITGA10	Integrin Subunit Alpha 10	Protein Coding	5
158	ITGA11	Integrin Subunit Alpha 11	Protein Coding	5
159	ITGA2	Integrin Subunit Alpha 2	Protein Coding	5
160	ITGA2B	Integrin Subunit Alpha 2b	Protein Coding	5
161	ITGA3	Integrin Subunit Alpha 3	Protein Coding	5
162	ITGA4	Integrin Subunit Alpha 4	Protein Coding	5
163	ITGA5	Integrin Subunit Alpha 5	Protein Coding	5
164	ITGA6	Integrin Subunit Alpha 6	Protein Coding	5
165	ITGA7	Integrin Subunit Alpha 7	Protein Coding	5
166	ITGA8	Integrin Subunit Alpha 8	Protein Coding	5
167	ITGA9	Integrin Subunit Alpha 9	Protein Coding	5
168	ITGAD	Integrin Subunit Alpha D	Protein Coding	5
169	ITGAE	Integrin Subunit Alpha E	Protein Coding	5
170	ITGAL	Integrin Subunit Alpha L	Protein Coding	5
171	ITGAM	Integrin Subunit Alpha M	Protein Coding	5
172	ITGAV	Integrin Subunit Alpha V	Protein Coding	5
173	ITGAX	Integrin Subunit Alpha X	Protein Coding	5
174	ITGB1	Integrin Subunit Beta 1	Protein Coding	5
175	ITGB2	Integrin Subunit Beta 2	Protein Coding	5
176	ITGB3	Integrin Subunit Beta 3	Protein Coding	5
177	ITGB4	Integrin Subunit Beta 4	Protein Coding	5
178	ITGB5	Integrin Subunit Beta 5	Protein Coding	5
179	ITGB6	Integrin Subunit Beta 6	Protein Coding	5
180	ITGB7	Integrin Subunit Beta 7	Protein Coding	5
181	ITGB8	Integrin Subunit Beta 8	Protein Coding	5
182	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	5
183	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	5
184	FAS	Fas Cell Surface Death Receptor	Protein Coding	4
185	FASLG	Fas Ligand	Protein Coding	4
186	GNAS	GNAS Complex Locus	Protein Coding	4
187	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	4
188	MAPK12	Mitogen-Activated Protein Kinase 12	Protein Coding	4
189	MAPK7	Mitogen-Activated Protein Kinase 7	Protein Coding	4
190	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	4
191	APAF1	Apoptotic Peptidase Activating Factor 1	Protein Coding	4
192	ATM	ATM Serine/Threonine Kinase	Protein Coding	4
193	BAD	BCL2 Associated Agonist Of Cell Death	Protein Coding	4
194	BAX	BCL2 Associated X, Apoptosis Regulator	Protein Coding	4
195	BCL2	BCL2 Apoptosis Regulator	Protein Coding	4
196	BID	BH3 Interacting Domain Death Agonist	Protein Coding	4
197	CASP3	Caspase 3	Protein Coding	4
198	CASP9	Caspase 9	Protein Coding	4
199	CYCS	Cytochrome C, Somatic	Protein Coding	4
200	FADD	Fas Associated Via Death Domain	Protein Coding	3
201	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	3
202	TNF	Tumor Necrosis Factor	Protein Coding	3
203	TNFRSF1A	TNF Receptor Superfamily Member 1A	Protein Coding	3
204	GNA11	G Protein Subunit Alpha 11	Protein Coding	3
205	GNA12	G Protein Subunit Alpha 12	Protein Coding	3
206	GNA13	G Protein Subunit Alpha 13	Protein Coding	3
207	GNA14	G Protein Subunit Alpha 14	Protein Coding	3
208	GNA15	G Protein Subunit Alpha 15	Protein Coding	3
209	GNAL	G Protein Subunit Alpha L	Protein Coding	3
210	GNB1	G Protein Subunit Beta 1	Protein Coding	3
211	GNB2	G Protein Subunit Beta 2	Protein Coding	3
212	GNB3	G Protein Subunit Beta 3	Protein Coding	3
213	GNB4	G Protein Subunit Beta 4	Protein Coding	3
214	GNB5	G Protein Subunit Beta 5	Protein Coding	3
215	GNG2	G Protein Subunit Gamma 2	Protein Coding	3
216	GNG3	G Protein Subunit Gamma 3	Protein Coding	3
217	GNG4	G Protein Subunit Gamma 4	Protein Coding	3
218	GPR119	G Protein-Coupled Receptor 119	Protein Coding	3
219	P2RY13	Purinergic Receptor P2Y13	Protein Coding	3
220	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	3
221	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	3
222	MAP2K3	Mitogen-Activated Protein Kinase Kinase 3	Protein Coding	3
223	MAP2K4	Mitogen-Activated Protein Kinase Kinase 4	Protein Coding	3
224	MAP2K5	Mitogen-Activated Protein Kinase Kinase 5	Protein Coding	3
225	MAP2K6	Mitogen-Activated Protein Kinase Kinase 6	Protein Coding	3
226	MAPK6	Mitogen-Activated Protein Kinase 6	Protein Coding	3
227	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	3
228	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	3
229	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	3
230	PRKAR1A	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha	Protein Coding	3
231	PRKAR1B	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Beta	Protein Coding	3
232	PRKAR2A	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Alpha	Protein Coding	3
233	PRKAR2B	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Beta	Protein Coding	3
234	SOS1	SOS Ras/Rac Guanine Nucleotide Exchange Factor 1	Protein Coding	3
235	SOS2	SOS Ras/Rho Guanine Nucleotide Exchange Factor 2	Protein Coding	3
236	RHOA	Ras Homolog Family Member A	Protein Coding	3
237	PRKCI	Protein Kinase C Iota	Protein Coding	3
238	PRKCZ	Protein Kinase C Zeta	Protein Coding	3
239	BBC3	BCL2 Binding Component 3	Protein Coding	3
240	BCL2L1	BCL2 Like 1	Protein Coding	3
241	CHEK2	Checkpoint Kinase 2	Protein Coding	3
242	MDM2	MDM2 Proto-Oncogene	Protein Coding	3
243	TP53AIP1	Tumor Protein P53 Regulated Apoptosis Inducing Protein 1	Protein Coding	3
244	PMAIP1	Phorbol-12-Myristate-13-Acetate-Induced Protein 1	Protein Coding	3
245	PRKCA	Protein Kinase C Alpha	Protein Coding	3
246	PRKCB	Protein Kinase C Beta	Protein Coding	3
247	PRKCD	Protein Kinase C Delta	Protein Coding	3
248	PRKCE	Protein Kinase C Epsilon	Protein Coding	3
249	PRKCG	Protein Kinase C Gamma	Protein Coding	3
250	PRKCH	Protein Kinase C Eta	Protein Coding	3
251	RPS6KA1	Ribosomal Protein S6 Kinase A1	Protein Coding	3
252	RPS6KA2	Ribosomal Protein S6 Kinase A2	Protein Coding	3
253	RPS6KA3	Ribosomal Protein S6 Kinase A3	Protein Coding	3
254	RPS6KA4	Ribosomal Protein S6 Kinase A4	Protein Coding	3
255	RPS6KA6	Ribosomal Protein S6 Kinase A6	Protein Coding	3
256	CFLAR	CASP8 And FADD Like Apoptosis Regulator	Protein Coding	2
257	LTA	Lymphotoxin Alpha	Protein Coding	2
258	TNFRSF1B	TNF Receptor Superfamily Member 1B	Protein Coding	2
259	ARHGEF6	Rac/Cdc42 Guanine Nucleotide Exchange Factor 6	Protein Coding	2
260	BRAF	B-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	2
261	INSR	Insulin Receptor	Protein Coding	2
262	MCF2L	MCF.2 Cell Line Derived Transforming Sequence Like	Protein Coding	2
263	ACTR2	Actin Related Protein 2	Protein Coding	2
264	ACTR3	Actin Related Protein 3	Protein Coding	2
265	RHOB	Ras Homolog Family Member B	Protein Coding	2
266	RHOC	Ras Homolog Family Member C	Protein Coding	2
267	RHOD	Ras Homolog Family Member D	Protein Coding	2
268	RND3	Rho Family GTPase 3	Protein Coding	2
269	RHOG	Ras Homolog Family Member G	Protein Coding	2
270	RHOH	Ras Homolog Family Member H	Protein Coding	2
271	DIRAS3	DIRAS Family GTPase 3	Protein Coding	2
272	RND2	Rho Family GTPase 2	Protein Coding	2
273	BAIAP2	BAR/IMD Domain Containing Adaptor Protein 2	Protein Coding	2
274	CDC42	Cell Division Cycle 42	Protein Coding	2
275	CFL1	Cofilin 1	Protein Coding	2
276	CFL2	Cofilin 2	Protein Coding	2
277	GNAI1	G Protein Subunit Alpha I1	Protein Coding	2
278	GNAI2	G Protein Subunit Alpha I2	Protein Coding	2
279	GNAI3	G Protein Subunit Alpha I3	Protein Coding	2
280	GNAO1	G Protein Subunit Alpha O1	Protein Coding	2
281	GNAT1	G Protein Subunit Alpha Transducin 1	Protein Coding	2
282	GNAT2	G Protein Subunit Alpha Transducin 2	Protein Coding	2
283	GNAZ	G Protein Subunit Alpha Z	Protein Coding	2
284	GNG10	G Protein Subunit Gamma 10	Protein Coding	2
285	GNG11	G Protein Subunit Gamma 11	Protein Coding	2
286	GNG12	G Protein Subunit Gamma 12	Protein Coding	2
287	GNG13	G Protein Subunit Gamma 13	Protein Coding	2
288	GNG5	G Protein Subunit Gamma 5	Protein Coding	2
289	GNG7	G Protein Subunit Gamma 7	Protein Coding	2
290	GNG8	G Protein Subunit Gamma 8	Protein Coding	2
291	GNGT1	G Protein Subunit Gamma Transducin 1	Protein Coding	2
292	GNGT2	G Protein Subunit Gamma Transducin 2	Protein Coding	2
293	LIMK1	LIM Domain Kinase 1	Protein Coding	2
294	LIMK2	LIM Domain Kinase 2	Protein Coding	2
295	PAK1	P21 (RAC1) Activated Kinase 1	Protein Coding	2
296	PAK2	P21 (RAC1) Activated Kinase 2	Protein Coding	2
297	PAK3	P21 (RAC1) Activated Kinase 3	Protein Coding	2
298	PAK4	P21 (RAC1) Activated Kinase 4	Protein Coding	2
299	PAK6	P21 (RAC1) Activated Kinase 6	Protein Coding	2
300	PAK5	P21 (RAC1) Activated Kinase 5	Protein Coding	2
301	PIP5K1A	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Alpha	Protein Coding	2
302	PIP5K1B	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Beta	Protein Coding	2
303	PIP5K1C	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Gamma	Protein Coding	2
304	PIP4K2A	Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Alpha	Protein Coding	2
305	PIP4K2B	Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Beta	Protein Coding	2
306	PIP4K2C	Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Gamma	Protein Coding	2
307	PPP1R12A	Protein Phosphatase 1 Regulatory Subunit 12A	Protein Coding	2
308	PPP1R12B	Protein Phosphatase 1 Regulatory Subunit 12B	Protein Coding	2
309	RAC1	Rac Family Small GTPase 1	Protein Coding	2
310	WASF1	WASP Family Member 1	Protein Coding	2
311	CD44	CD44 Molecule (IN Blood Group)	Protein Coding	2
312	ELK4	ETS Transcription Factor ELK4	Protein Coding	2
313	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	2
314	PTK2	Protein Tyrosine Kinase 2	Protein Coding	2
315	PTK2B	Protein Tyrosine Kinase 2 Beta	Protein Coding	2
316	GSK3B	Glycogen Synthase Kinase 3 Beta	Protein Coding	2
317	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	2
318	BAK1	BCL2 Antagonist/Killer 1	Protein Coding	2
319	BCL2L11	BCL2 Like 11	Protein Coding	2
320	BIRC2	Baculoviral IAP Repeat Containing 2	Protein Coding	2
321	TSPO	Translocator Protein	Protein Coding	2
322	CASP7	Caspase 7	Protein Coding	2
323	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	2
324	ENDOG	Endonuclease G	Protein Coding	2
325	AIFM1	Apoptosis Inducing Factor Mitochondria Associated 1	Protein Coding	2
326	PPID	Peptidylprolyl Isomerase D	Protein Coding	2
327	PRKD1	Protein Kinase D1	Protein Coding	2
328	PRKD3	Protein Kinase D3	Protein Coding	2
329	PRKCQ	Protein Kinase C Theta	Protein Coding	2
330	PRPS1	Phosphoribosyl Pyrophosphate Synthetase 1	Protein Coding	2
331	HTRA2	HtrA Serine Peptidase 2	Protein Coding	2
332	RPS6KA5	Ribosomal Protein S6 Kinase A5	Protein Coding	2
333	SLC25A4	Solute Carrier Family 25 Member 4	Protein Coding	2
334	SLC25A5	Solute Carrier Family 25 Member 5	Protein Coding	2
335	SLC25A6	Solute Carrier Family 25 Member 6	Protein Coding	2
336	DIABLO	Diablo IAP-Binding Mitochondrial Protein	Protein Coding	2
337	TNFSF10	TNF Superfamily Member 10	Protein Coding	2
338	VDAC1	Voltage Dependent Anion Channel 1	Protein Coding	2
339	VDAC1P4	Voltage Dependent Anion Channel 1 Pseudogene 4	Pseudogene	2
340	VDAC2	Voltage Dependent Anion Channel 2	Protein Coding	2
341	VDAC3	Voltage Dependent Anion Channel 3	Protein Coding	2
342	ATF4	Activating Transcription Factor 4	Protein Coding	2
343	CREB1	CAMP Responsive Element Binding Protein 1	Protein Coding	2
344	CREB3	CAMP Responsive Element Binding Protein 3	Protein Coding	2
345	CREB3L4	CAMP Responsive Element Binding Protein 3 Like 4	Protein Coding	2
346	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	2
347	EP300	EP300 Lysine Acetyltransferase	Protein Coding	2
348	NCOA1	Nuclear Receptor Coactivator 1	Protein Coding	2
349	POLR2A	RNA Polymerase II Subunit A	Protein Coding	2
350	POLR2B	RNA Polymerase II Subunit B	Protein Coding	2
351	POLR2C	RNA Polymerase II Subunit C	Protein Coding	2
352	RXRA	Retinoid X Receptor Alpha	Protein Coding	2
353	RXRB	Retinoid X Receptor Beta	Protein Coding	2
354	RXRG	Retinoid X Receptor Gamma	Protein Coding	2
355	MAPK11	Mitogen-Activated Protein Kinase 11	Protein Coding	2
356	MAPK13	Mitogen-Activated Protein Kinase 13	Protein Coding	2
357	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	2
358	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	2
359	YWHAB	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Beta	Protein Coding	2
360	YWHAE	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon	Protein Coding	2
361	YWHAG	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Gamma	Protein Coding	2
362	YWHAH	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Eta	Protein Coding	2
363	YWHAQ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Theta	Protein Coding	2
364	YWHAZ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta	Protein Coding	2
365	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	2
366	AKT3	AKT Serine/Threonine Kinase 3	Protein Coding	2
367	CASP6	Caspase 6	Protein Coding	2
368	XIAP	X-Linked Inhibitor Of Apoptosis	Protein Coding	1
369	ARHGEF1	Rho Guanine Nucleotide Exchange Factor 1	Protein Coding	1
370	ARHGEF10	Rho Guanine Nucleotide Exchange Factor 10	Protein Coding	1
371	ARHGEF11	Rho Guanine Nucleotide Exchange Factor 11	Protein Coding	1
372	ARHGEF12	Rho Guanine Nucleotide Exchange Factor 12	Protein Coding	1
373	ARHGEF15	Rho Guanine Nucleotide Exchange Factor 15	Protein Coding	1
374	ARHGEF16	Rho Guanine Nucleotide Exchange Factor 16	Protein Coding	1
375	ARHGEF2	Rho/Rac Guanine Nucleotide Exchange Factor 2	Protein Coding	1
376	ARHGEF3	Rho Guanine Nucleotide Exchange Factor 3	Protein Coding	1
377	ARHGEF4	Rho Guanine Nucleotide Exchange Factor 4	Protein Coding	1
378	ARHGEF5	Rho Guanine Nucleotide Exchange Factor 5	Protein Coding	1
379	ARHGEF7	Rho Guanine Nucleotide Exchange Factor 7	Protein Coding	1
380	ARHGEF9	Cdc42 Guanine Nucleotide Exchange Factor 9	Protein Coding	1
381	CACNA1A	Calcium Voltage-Gated Channel Subunit Alpha1 A	Protein Coding	1
382	CACNA1B	Calcium Voltage-Gated Channel Subunit Alpha1 B	Protein Coding	1
383	CACNA1C	Calcium Voltage-Gated Channel Subunit Alpha1 C	Protein Coding	1
384	CACNA1D	Calcium Voltage-Gated Channel Subunit Alpha1 D	Protein Coding	1
385	CACNA1E	Calcium Voltage-Gated Channel Subunit Alpha1 E	Protein Coding	1
386	CACNA1F	Calcium Voltage-Gated Channel Subunit Alpha1 F	Protein Coding	1
387	CACNA1G	Calcium Voltage-Gated Channel Subunit Alpha1 G	Protein Coding	1
388	CACNA1H	Calcium Voltage-Gated Channel Subunit Alpha1 H	Protein Coding	1
389	CACNA1I	Calcium Voltage-Gated Channel Subunit Alpha1 I	Protein Coding	1
390	CACNA1S	Calcium Voltage-Gated Channel Subunit Alpha1 S	Protein Coding	1
391	CACNA2D1	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 1	Protein Coding	1
392	CACNA2D2	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 2	Protein Coding	1
393	CACNA2D3	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 3	Protein Coding	1
394	CACNA2D4	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 4	Protein Coding	1
395	CACNB1	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 1	Protein Coding	1
396	CACNB2	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 2	Protein Coding	1
397	CACNB3	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 3	Protein Coding	1
398	CACNB4	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 4	Protein Coding	1
399	CACNG1	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 1	Protein Coding	1
400	CACNG2	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 2	Protein Coding	1
401	CACNG3	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 3	Protein Coding	1
402	CACNG4	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 4	Protein Coding	1
403	CACNG5	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 5	Protein Coding	1
404	CACNG6	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 6	Protein Coding	1
405	CACNG7	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 7	Protein Coding	1
406	CACNG8	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 8	Protein Coding	1
407	CBL	Cbl Proto-Oncogene	Protein Coding	1
408	CD3E	CD3 Epsilon Subunit Of T-Cell Receptor Complex	Protein Coding	1
409	CD247	CD247 Molecule	Protein Coding	1
410	CRKL	CRK Like Proto-Oncogene, Adaptor Protein	Protein Coding	1
411	EPOR	Erythropoietin Receptor	Protein Coding	1
412	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	Protein Coding	1
413	ERBB3	Erb-B2 Receptor Tyrosine Kinase 3	Protein Coding	1
414	ERBB4	Erb-B2 Receptor Tyrosine Kinase 4	Protein Coding	1
415	FYB1	FYN Binding Protein 1	Protein Coding	1
416	FYN	FYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
417	GRAP2	GRB2 Related Adaptor Protein 2	Protein Coding	1
418	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	1
419	ITPR2	Inositol 1,4,5-Trisphosphate Receptor Type 2	Protein Coding	1
420	ITPR3	Inositol 1,4,5-Trisphosphate Receptor Type 3	Protein Coding	1
421	LAT	Linker For Activation Of T Cells	Protein Coding	1
422	LCK	LCK Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
423	LCP2	Lymphocyte Cytosolic Protein 2	Protein Coding	1
424	LIFR	LIF Receptor Subunit Alpha	Protein Coding	1
425	NET1	Neuroepithelial Cell Transforming 1	Protein Coding	1
426	PLCE1	Phospholipase C Epsilon 1	Protein Coding	1
427	PLCG1	Phospholipase C Gamma 1	Protein Coding	1
428	RAP1A	RAP1A, Member Of RAS Oncogene Family	Protein Coding	1
429	RAP1B	RAP1B, Member Of RAS Oncogene Family	Protein Coding	1
430	RAP1GAP	RAP1 GTPase Activating Protein	Protein Coding	1
431	RAPGEF1	Rap Guanine Nucleotide Exchange Factor 1	Protein Coding	1
432	RASGRP1	RAS Guanyl Releasing Protein 1	Protein Coding	1
433	RASGRP2	RAS Guanyl Releasing Protein 2	Protein Coding	1
434	ZAP70	Zeta Chain Of T Cell Receptor Associated Protein Kinase 70	Protein Coding	1
435	ACTA1	Actin Alpha 1, Skeletal Muscle	Protein Coding	1
436	ACTA2	Actin Alpha 2, Smooth Muscle	Protein Coding	1
437	ACTB	Actin Beta	Protein Coding	1
438	ACTG1	Actin Gamma 1	Protein Coding	1
439	ACTG2	Actin Gamma 2, Smooth Muscle	Protein Coding	1
440	ARHGDIA	Rho GDP Dissociation Inhibitor Alpha	Protein Coding	1
441	ARHGDIB	Rho GDP Dissociation Inhibitor Beta	Protein Coding	1
442	RHOJ	Ras Homolog Family Member J	Protein Coding	1
443	RHOQ	Ras Homolog Family Member Q	Protein Coding	1
444	GSN	Gelsolin	Protein Coding	1
445	MYL9	Myosin Light Chain 9	Protein Coding	1
446	MYLK	Myosin Light Chain Kinase	Protein Coding	1
447	PFN1	Profilin 1	Protein Coding	1
448	PFN2	Profilin 2	Protein Coding	1
449	PPP1CB	Protein Phosphatase 1 Catalytic Subunit Beta	Protein Coding	1
450	RAC2	Rac Family Small GTPase 2	Protein Coding	1
451	RAC3	Rac Family Small GTPase 3	Protein Coding	1
452	ROCK1	Rho Associated Coiled-Coil Containing Protein Kinase 1	Protein Coding	1
453	ROCK2	Rho Associated Coiled-Coil Containing Protein Kinase 2	Protein Coding	1
454	WASL	WASP Like Actin Nucleation Promoting Factor	Protein Coding	1
455	ABI2	Abl Interactor 2	Protein Coding	1
456	ANK1	Ankyrin 1	Protein Coding	1
457	ARFIP2	ARF Interacting Protein 2	Protein Coding	1
458	BRK1	BRICK1 Subunit Of SCAR/WAVE Actin Nucleating Complex	Protein Coding	1
459	CDK5R1	Cyclin Dependent Kinase 5 Regulatory Subunit 1	Protein Coding	1
460	CYFIP1	Cytoplasmic FMR1 Interacting Protein 1	Protein Coding	1
461	CYFIP2	Cytoplasmic FMR1 Interacting Protein 2	Protein Coding	1
462	ELK1	ETS Transcription Factor ELK1	Protein Coding	1
463	IQGAP1	IQ Motif Containing GTPase Activating Protein 1	Protein Coding	1
464	IQGAP2	IQ Motif Containing GTPase Activating Protein 2	Protein Coding	1
465	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
466	MAP2K7	Mitogen-Activated Protein Kinase Kinase 7	Protein Coding	1
467	MAP3K11	Mitogen-Activated Protein Kinase Kinase Kinase 11	Protein Coding	1
468	NCF2	Neutrophil Cytosolic Factor 2	Protein Coding	1
469	NCKAP1	NCK Associated Protein 1	Protein Coding	1
470	NOX1	NADPH Oxidase 1	Protein Coding	1
471	NOX3	NADPH Oxidase 3	Protein Coding	1
472	NOX4	NADPH Oxidase 4	Protein Coding	1
473	NOX5	NADPH Oxidase 5	Protein Coding	1
474	PARD3	Par-3 Family Cell Polarity Regulator	Protein Coding	1
475	PARD6A	Par-6 Family Cell Polarity Regulator Alpha	Protein Coding	1
476	PLD1	Phospholipase D1	Protein Coding	1
477	RACGAP1	Rac GTPase Activating Protein 1	Protein Coding	1
478	RPS6KB1	Ribosomal Protein S6 Kinase B1	Protein Coding	1
479	SH3RF1	SH3 Domain Containing Ring Finger 1	Protein Coding	1
480	TIAM1	TIAM Rac1 Associated GEF 1	Protein Coding	1
481	ARAF	A-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
482	EIF1AX	Eukaryotic Translation Initiation Factor 1A X-Linked	Protein Coding	1
483	EIF1AY	Eukaryotic Translation Initiation Factor 1A Y-Linked	Protein Coding	1
484	EIF2A	Eukaryotic Translation Initiation Factor 2A	Protein Coding	1
485	EIF2AK3	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3	Protein Coding	1
486	EIF2AK4	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4	Protein Coding	1
487	EIF2B1	Eukaryotic Translation Initiation Factor 2B Subunit Alpha	Protein Coding	1
488	EIF2B2	Eukaryotic Translation Initiation Factor 2B Subunit Beta	Protein Coding	1
489	EIF2B3	Eukaryotic Translation Initiation Factor 2B Subunit Gamma	Protein Coding	1
490	EIF2B4	Eukaryotic Translation Initiation Factor 2B Subunit Delta	Protein Coding	1
491	EIF2B5	Eukaryotic Translation Initiation Factor 2B Subunit Epsilon	Protein Coding	1
492	AGO1	Argonaute RISC Component 1	Protein Coding	1
493	AGO2	Argonaute RISC Catalytic Component 2	Protein Coding	1
494	EIF2S1	Eukaryotic Translation Initiation Factor 2 Subunit Alpha	Protein Coding	1
495	EIF2S2	Eukaryotic Translation Initiation Factor 2 Subunit Beta	Protein Coding	1
496	EIF2S3	Eukaryotic Translation Initiation Factor 2 Subunit Gamma	Protein Coding	1
497	EIF3J	Eukaryotic Translation Initiation Factor 3 Subunit J	Protein Coding	1
498	EIF3A	Eukaryotic Translation Initiation Factor 3 Subunit A	Protein Coding	1
499	EIF3I	Eukaryotic Translation Initiation Factor 3 Subunit I	Protein Coding	1
500	EIF3H	Eukaryotic Translation Initiation Factor 3 Subunit H	Protein Coding	1
501	EIF3G	Eukaryotic Translation Initiation Factor 3 Subunit G	Protein Coding	1
502	EIF3F	Eukaryotic Translation Initiation Factor 3 Subunit F	Protein Coding	1
503	EIF3E	Eukaryotic Translation Initiation Factor 3 Subunit E	Protein Coding	1
504	EIF3D	Eukaryotic Translation Initiation Factor 3 Subunit D	Protein Coding	1
505	EIF3C	Eukaryotic Translation Initiation Factor 3 Subunit C	Protein Coding	1
506	EIF3B	Eukaryotic Translation Initiation Factor 3 Subunit B	Protein Coding	1
507	EIF4A1	Eukaryotic Translation Initiation Factor 4A1	Protein Coding	1
508	EIF4A2	Eukaryotic Translation Initiation Factor 4A2	Protein Coding	1
509	EIF4E	Eukaryotic Translation Initiation Factor 4E	Protein Coding	1
510	EIF4G1	Eukaryotic Translation Initiation Factor 4 Gamma 1	Protein Coding	1
511	EIF4G2	Eukaryotic Translation Initiation Factor 4 Gamma 2	Protein Coding	1
512	EIF4G3	Eukaryotic Translation Initiation Factor 4 Gamma 3	Protein Coding	1
513	EIF5	Eukaryotic Translation Initiation Factor 5	Protein Coding	1
514	EIF5A	Eukaryotic Translation Initiation Factor 5A	Protein Coding	1
515	EIF5A2	Eukaryotic Translation Initiation Factor 5A2	Protein Coding	1
516	EIF2AK1	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 1	Protein Coding	1
517	INS	Insulin	Protein Coding	1
518	PABPC1	Poly(A) Binding Protein Cytoplasmic 1	Protein Coding	1
519	PPP1R10	Protein Phosphatase 1 Regulatory Subunit 10	Protein Coding	1
520	PPP1R11	Protein Phosphatase 1 Regulatory Inhibitor Subunit 11	Protein Coding	1
521	PPP1R12C	Protein Phosphatase 1 Regulatory Subunit 12C	Protein Coding	1
522	PPP1R13B	Protein Phosphatase 1 Regulatory Subunit 13B	Protein Coding	1
523	PPP1R14A	Protein Phosphatase 1 Regulatory Inhibitor Subunit 14A	Protein Coding	1
524	PPP1R14B	Protein Phosphatase 1 Regulatory Inhibitor Subunit 14B	Protein Coding	1
525	PPP1R15A	Protein Phosphatase 1 Regulatory Subunit 15A	Protein Coding	1
526	PPP1R16A	Protein Phosphatase 1 Regulatory Subunit 16A	Protein Coding	1
527	PPP1R1A	Protein Phosphatase 1 Regulatory Inhibitor Subunit 1A	Protein Coding	1
528	PPP1R1B	Protein Phosphatase 1 Regulatory Inhibitor Subunit 1B	Protein Coding	1
529	PPP1R2	Protein Phosphatase 1 Regulatory Inhibitor Subunit 2	Protein Coding	1
530	PPP1R3A	Protein Phosphatase 1 Regulatory Subunit 3A	Protein Coding	1
531	PPP1R3B	Protein Phosphatase 1 Regulatory Subunit 3B	Protein Coding	1
532	PPP1R3C	Protein Phosphatase 1 Regulatory Subunit 3C	Protein Coding	1
533	PPP1R3D	Protein Phosphatase 1 Regulatory Subunit 3D	Protein Coding	1
534	PPP1R3F	Protein Phosphatase 1 Regulatory Subunit 3F	Protein Coding	1
535	PPP1R7	Protein Phosphatase 1 Regulatory Subunit 7	Protein Coding	1
536	PPP1R8	Protein Phosphatase 1 Regulatory Subunit 8	Protein Coding	1
537	PPP1R9A	Protein Phosphatase 1 Regulatory Subunit 9A	Protein Coding	1
538	PPP1R9B	Protein Phosphatase 1 Regulatory Subunit 9B	Protein Coding	1
539	EIF2AK2	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2	Protein Coding	1
540	TP53BP2	Tumor Protein P53 Binding Protein 2	Protein Coding	1
541	PARP1	Poly(ADP-Ribose) Polymerase 1	Protein Coding	1
542	PARP4	Poly(ADP-Ribose) Polymerase Family Member 4	Protein Coding	1
543	PARP3	Poly(ADP-Ribose) Polymerase Family Member 3	Protein Coding	1
544	PARP11	Poly(ADP-Ribose) Polymerase Family Member 11	Protein Coding	1
545	CHUK	Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex	Protein Coding	1
546	DAPK3	Death Associated Protein Kinase 3	Protein Coding	1
547	DAXX	Death Domain Associated Protein	Protein Coding	1
548	DFFA	DNA Fragmentation Factor Subunit Alpha	Protein Coding	1
549	PARP10	Poly(ADP-Ribose) Polymerase Family Member 10	Protein Coding	1
550	PARP16	Poly(ADP-Ribose) Polymerase Family Member 16	Protein Coding	1
551	PARP8	Poly(ADP-Ribose) Polymerase Family Member 8	Protein Coding	1
552	PARP15	Poly(ADP-Ribose) Polymerase Family Member 15	Protein Coding	1
553	IKBKB	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Beta	Protein Coding	1
554	IKBKE	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Epsilon	Protein Coding	1
555	IKBKG	Inhibitor Of Nuclear Factor Kappa B Kinase Regulatory Subunit Gamma	Protein Coding	1
556	PARP14	Poly(ADP-Ribose) Polymerase Family Member 14	Protein Coding	1
557	NFKBIA	NFKB Inhibitor Alpha	Protein Coding	1
558	NFKBIB	NFKB Inhibitor Beta	Protein Coding	1
559	NFKBIE	NFKB Inhibitor Epsilon	Protein Coding	1
560	PAWR	Pro-Apoptotic WT1 Regulator	Protein Coding	1
561	PML	PML Nuclear Body Scaffold	Protein Coding	1
562	RIPK1	Receptor Interacting Serine/Threonine Kinase 1	Protein Coding	1
563	TNFRSF10A	TNF Receptor Superfamily Member 10a	Protein Coding	1
564	TNFSF12	TNF Superfamily Member 12	Protein Coding	1
565	TRADD	TNFRSF1A Associated Via Death Domain	Protein Coding	1
566	TRAF2	TNF Receptor Associated Factor 2	Protein Coding	1
567	CARM1	Coactivator Associated Arginine Methyltransferase 1	Protein Coding	1
568	CRABP2	Cellular Retinoic Acid Binding Protein 2	Protein Coding	1
569	GRIP1	Glutamate Receptor Interacting Protein 1	Protein Coding	1
570	GTF2A1	General Transcription Factor IIA Subunit 1	Protein Coding	1
571	GTF2A2	General Transcription Factor IIA Subunit 2	Protein Coding	1
572	GTF2B	General Transcription Factor IIB	Protein Coding	1
573	GTF2E1	General Transcription Factor IIE Subunit 1	Protein Coding	1
574	GTF2E2	General Transcription Factor IIE Subunit 2	Protein Coding	1
575	GTF2H1	General Transcription Factor IIH Subunit 1	Protein Coding	1
576	GTF2H2	General Transcription Factor IIH Subunit 2	Protein Coding	1
577	GTF2H3	General Transcription Factor IIH Subunit 3	Protein Coding	1
578	GTF2H4	General Transcription Factor IIH Subunit 4	Protein Coding	1
579	GTF2H5	General Transcription Factor IIH Subunit 5	Protein Coding	1
580	H3-3A	H3.3 Histone A	Protein Coding	1
581	H3-3B	H3.3 Histone B	Protein Coding	1
582	HAT1	Histone Acetyltransferase 1	Protein Coding	1
583	H3C1	H3 Clustered Histone 1	Protein Coding	1
584	H3C2	H3 Clustered Histone 2	Protein Coding	1
585	H3C3	H3 Clustered Histone 3	Protein Coding	1
586	H3C4	H3 Clustered Histone 4	Protein Coding	1
587	H3C6	H3 Clustered Histone 6	Protein Coding	1
588	H3C7	H3 Clustered Histone 7	Protein Coding	1
589	H3C8	H3 Clustered Histone 8	Protein Coding	1
590	H3C10	H3 Clustered Histone 10	Protein Coding	1
591	H3C11	H3 Clustered Histone 11	Protein Coding	1
592	H3C12	H3 Clustered Histone 12	Protein Coding	1
593	H4C1	H4 Clustered Histone 1	Protein Coding	1
594	H4C2	H4 Clustered Histone 2	Protein Coding	1
595	H4C3	H4 Clustered Histone 3	Protein Coding	1
596	H4C4	H4 Clustered Histone 4	Protein Coding	1
597	H4C5	H4 Clustered Histone 5	Protein Coding	1
598	H4C6	H4 Clustered Histone 6	Protein Coding	1
599	H4C7	H4 Clustered Histone 7	Protein Coding	1
600	H4C8	H4 Clustered Histone 8	Protein Coding	1
601	H4C9	H4 Clustered Histone 9	Protein Coding	1
602	H4C11	H4 Clustered Histone 11	Protein Coding	1
603	H4C12	H4 Clustered Histone 12	Protein Coding	1
604	H4C13	H4 Clustered Histone 13	Protein Coding	1
605	H4C14	H4 Clustered Histone 14	Protein Coding	1
606	H3-4	H3.4 Histone, Cluster Member	Protein Coding	1
607	PRMT1	Protein Arginine Methyltransferase 1	Protein Coding	1
608	NCOA3	Nuclear Receptor Coactivator 3	Protein Coding	1
609	KAT2B	Lysine Acetyltransferase 2B	Protein Coding	1
610	RARA	Retinoic Acid Receptor Alpha	Protein Coding	1
611	RARB	Retinoic Acid Receptor Beta	Protein Coding	1
612	RARG	Retinoic Acid Receptor Gamma	Protein Coding	1
613	RBP5	Retinol Binding Protein 5	Protein Coding	1
614	TAF1	TATA-Box Binding Protein Associated Factor 1	Protein Coding	1
615	TAF10	TATA-Box Binding Protein Associated Factor 10	Protein Coding	1
616	TAF11	TATA-Box Binding Protein Associated Factor 11	Protein Coding	1
617	TAF12	TATA-Box Binding Protein Associated Factor 12	Protein Coding	1
618	TAF13	TATA-Box Binding Protein Associated Factor 13	Protein Coding	1
619	TAF15	TATA-Box Binding Protein Associated Factor 15	Protein Coding	1
620	TAF1A	TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit A	Protein Coding	1
621	TAF1B	TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit B	Protein Coding	1
622	TAF1C	TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit C	Protein Coding	1
623	TAF1L	TATA-Box Binding Protein Associated Factor 1 Like	Protein Coding	1
624	TAF2	TATA-Box Binding Protein Associated Factor 2	Protein Coding	1
625	TAF4	TATA-Box Binding Protein Associated Factor 4	Protein Coding	1
626	TAF5	TATA-Box Binding Protein Associated Factor 5	Protein Coding	1
627	TAF5L	TATA-Box Binding Protein Associated Factor 5 Like	Protein Coding	1
628	TAF6	TATA-Box Binding Protein Associated Factor 6	Protein Coding	1
629	TAF6L	TATA-Box Binding Protein Associated Factor 6 Like	Protein Coding	1
630	TAF7	TATA-Box Binding Protein Associated Factor 7	Protein Coding	1
631	TAF7L	TATA-Box Binding Protein Associated Factor 7 Like	Protein Coding	1
632	TAF9	TATA-Box Binding Protein Associated Factor 9	Protein Coding	1
633	TAF9B	TATA-Box Binding Protein Associated Factor 9b	Protein Coding	1
634	TBP	TATA-Box Binding Protein	Protein Coding	1
635	ADCY1	Adenylate Cyclase 1	Protein Coding	1
636	ADCY2	Adenylate Cyclase 2	Protein Coding	1
637	ADCY3	Adenylate Cyclase 3	Protein Coding	1
638	MAP3K7	Mitogen-Activated Protein Kinase Kinase Kinase 7	Protein Coding	1
639	PPARA	Peroxisome Proliferator Activated Receptor Alpha	Protein Coding	1
640	PPARD	Peroxisome Proliferator Activated Receptor Delta	Protein Coding	1
641	PPARG	Peroxisome Proliferator Activated Receptor Gamma	Protein Coding	1
642	PTGIR	Prostaglandin I2 Receptor	Protein Coding	1
643	CTF1	Cardiotrophin 1	Protein Coding	1
644	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
645	FOSL1	FOS Like 1, AP-1 Transcription Factor Subunit	Protein Coding	1
646	FOXO3	Forkhead Box O3	Protein Coding	1
647	GAB1	GRB2 Associated Binding Protein 1	Protein Coding	1
648	IL6ST	Interleukin 6 Cytokine Family Signal Transducer	Protein Coding	1
649	LIF	LIF Interleukin 6 Family Cytokine	Protein Coding	1
650	MAP3K2	Mitogen-Activated Protein Kinase Kinase Kinase 2	Protein Coding	1
651	MAP3K3	Mitogen-Activated Protein Kinase Kinase Kinase 3	Protein Coding	1
652	MAP3K8	Mitogen-Activated Protein Kinase Kinase Kinase 8	Protein Coding	1
653	MEF2A	Myocyte Enhancer Factor 2A	Protein Coding	1
654	MEF2C	Myocyte Enhancer Factor 2C	Protein Coding	1
655	MEF2D	Myocyte Enhancer Factor 2D	Protein Coding	1
656	WNK1	WNK Lysine Deficient Protein Kinase 1	Protein Coding	1
657	SH2D2A	SH2 Domain Containing 2A	Protein Coding	1
658	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
659	CASP12	Caspase 12 (Gene/Pseudogene)	Protein Coding	1
660	ALOX15	Arachidonate 15-Lipoxygenase	Protein Coding	1
661	APP	Amyloid Beta Precursor Protein	Protein Coding	1
662	BCL2A1	BCL2 Related Protein A1	Protein Coding	1
663	BIK	BCL2 Interacting Killer	Protein Coding	1
664	CASP1	Caspase 1	Protein Coding	1
665	CASP10	Caspase 10	Protein Coding	1
666	CASP2	Caspase 2	Protein Coding	1
667	CASP4	Caspase 4	Protein Coding	1
668	CASP5	Caspase 5	Protein Coding	1
669	FOXO1	Forkhead Box O1	Protein Coding	1
670	GSK3A	Glycogen Synthase Kinase 3 Alpha	Protein Coding	1
671	IDE	Insulin Degrading Enzyme	Protein Coding	1
672	IL1B	Interleukin 1 Beta	Protein Coding	1
673	MAPT	Microtubule Associated Protein Tau	Protein Coding	1
674	PLA2G10	Phospholipase A2 Group X	Protein Coding	1
675	PLA2G12A	Phospholipase A2 Group XIIA	Protein Coding	1
676	PLA2G12B	Phospholipase A2 Group XIIB	Protein Coding	1
677	PLA2G1B	Phospholipase A2 Group IB	Protein Coding	1
678	PLA2G2A	Phospholipase A2 Group IIA	Protein Coding	1
679	PLA2G2D	Phospholipase A2 Group IID	Protein Coding	1
680	PLA2G2E	Phospholipase A2 Group IIE	Protein Coding	1
681	PLA2G2F	Phospholipase A2 Group IIF	Protein Coding	1
682	PLA2G3	Phospholipase A2 Group III	Protein Coding	1
683	PLA2G4A	Phospholipase A2 Group IVA	Protein Coding	1
684	PLA2G4C	Phospholipase A2 Group IVC	Protein Coding	1
685	PLA2G5	Phospholipase A2 Group V	Protein Coding	1
686	PLA2G6	Phospholipase A2 Group VI	Protein Coding	1
687	PLA2G7	Phospholipase A2 Group VII	Protein Coding	1
688	SERPINF1	Serpin Family F Member 1	Protein Coding	1
689	F2R	Coagulation Factor II Thrombin Receptor	Protein Coding	1
690	HMMR	Hyaluronan Mediated Motility Receptor	Protein Coding	1
691	MAPK10	Mitogen-Activated Protein Kinase 10	Protein Coding	1
692	MAPK4	Mitogen-Activated Protein Kinase 4	Protein Coding	1
693	MAPK9	Mitogen-Activated Protein Kinase 9	Protein Coding	1
694	MMP2	Matrix Metallopeptidase 2	Protein Coding	1
695	MMP9	Matrix Metallopeptidase 9	Protein Coding	1
696	PLAU	Plasminogen Activator, Urokinase	Protein Coding	1
697	PLAUR	Plasminogen Activator, Urokinase Receptor	Protein Coding	1
698	PLG	Plasminogen	Protein Coding	1
699	VTN	Vitronectin	Protein Coding	1
700	ABL1	ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase	Protein Coding	1
701	DKC1	Dyskerin Pseudouridine Synthase 1	Protein Coding	1
702	HSP90AA1	Heat Shock Protein 90 Alpha Family Class A Member 1	Protein Coding	1
703	POT1	Protection Of Telomeres 1	Protein Coding	1
704	PPP2R1A	Protein Phosphatase 2 Scaffold Subunit Aalpha	Protein Coding	1
705	PPP2R1B	Protein Phosphatase 2 Scaffold Subunit Abeta	Protein Coding	1
706	PPP2R2A	Protein Phosphatase 2 Regulatory Subunit Balpha	Protein Coding	1
707	PPP2R2B	Protein Phosphatase 2 Regulatory Subunit Bbeta	Protein Coding	1
708	PPP2R2C	Protein Phosphatase 2 Regulatory Subunit Bgamma	Protein Coding	1
709	PPP2R3A	Protein Phosphatase 2 Regulatory Subunit B''''Alpha	Protein Coding	1
710	PTPA	Protein Phosphatase 2 Phosphatase Activator	Protein Coding	1
711	PPP2R5A	Protein Phosphatase 2 Regulatory Subunit B''Alpha	Protein Coding	1
712	PPP2R5B	Protein Phosphatase 2 Regulatory Subunit B''Beta	Protein Coding	1
713	PPP2R5C	Protein Phosphatase 2 Regulatory Subunit B''Gamma	Protein Coding	1
714	PPP2R5D	Protein Phosphatase 2 Regulatory Subunit B''Delta	Protein Coding	1
715	PPP2R5E	Protein Phosphatase 2 Regulatory Subunit B''Epsilon	Protein Coding	1
716	PPP2R3B	Protein Phosphatase 2 Regulatory Subunit B''''Beta~Name Same As:- HGNC:9310	Protein Coding	1
717	RB1	RB Transcriptional Corepressor 1	Protein Coding	1
718	TEP1	Telomerase Associated Protein 1	Protein Coding	1
719	TERF1	Telomeric Repeat Binding Factor 1	Protein Coding	1
720	TERF2	Telomeric Repeat Binding Factor 2	Protein Coding	1
721	TERT	Telomerase Reverse Transcriptase	Protein Coding	1
722	TINF2	TERF1 Interacting Nuclear Factor 2	Protein Coding	1
723	TNKS	Tankyrase	Protein Coding	1
724	TNKS2	Tankyrase 2	Protein Coding	1
725	ATR	ATR Checkpoint Kinase	Protein Coding	1
726	CHEK1	Checkpoint Kinase 1	Protein Coding	1
727	PERP	P53 Apoptosis Effector Related To PMP22	Protein Coding	1
728	PTEN	Phosphatase And Tensin Homolog	Protein Coding	1
729	TNFRSF10B	TNF Receptor Superfamily Member 10b	Protein Coding	1

Disorders associated with Apoptotic Pathways in Synovial Fibroblasts SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Rasopathy	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, MRAS, NRAS, RAF1, RRAS2, SOS1, SOS2	16.00
2	Noonan syndrome and noonan-related syndrome	Enrichment	BRAF, CBL, HRAS, KRAS, MAP2K1, MAP2K2, NRAS, RAF1, SOS1	11.03
3	Noonan syndrome 1	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, MRAS, NRAS, RAF1, RRAS, RRAS2, SOS1, SOS2	10.60
4	Lung non-small cell carcinoma	Enrichment	BRAF, EGFR, ERBB2, HRAS, KRAS, MAP2K1, NRAS	9.47
5	Leukoencephalopathy with vanishing white matter 1	Enrichment	EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5	7.52
6	Pilomyxoid astrocytoma	Enrichment	BRAF, FGFR1, KRAS, NTRK2, RAF1	7.52
7	Bladder cancer	Enrichment	ATM, EGFR, FGFR3, KRAS, RB1, TERT, TP53	7.12
8	Leukoencephalopathy with vanishing white matter 5	Enrichment	EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5	7.10
9	Cardiofaciocutaneous syndrome 1	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	7.06
10	Cardiofaciocutaneous syndrome	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	7.06
11	Colorectal cancer	Enrichment	AKT1, ATM, BAX, CHEK2, FGFR2, FGFR3, IGF2, MET, PIK3R1, TP53	6.82
12	Gliosarcoma	Enrichment	ATM, EGFR, FGFR1, FGFR3, NFKBIA, TP53	6.77
13	Leukoencephalopathy with vanishing white matter	Enrichment	EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5	6.76
14	Giant cell glioblastoma	Enrichment	ATM, EGFR, FGFR1, FGFR3, NFKBIA, TP53	6.58
15	Lip and oral cavity carcinoma	Enrichment	ABL1, EGFR, KIT, RB1, TP53	6.56
16	Differentiated thyroid carcinoma	Enrichment	BRAF, EIF1AX, HRAS, KRAS, NRAS, NTRK1, NTRK3	6.33
17	Ovarian cancer	Enrichment	AKT1, ATM, CHEK2, EGFR, KIT, MET, NTRK1, PDGFRA, PTEN, TP53	6.21
18	Lung cancer susceptibility 3	Enrichment	EGFR, FGF10, KRAS, RB1, TP53	6.16
19	Li-fraumeni syndrome	Enrichment	CDKN2A, CHEK2, MDM2, TP53	6.15
20	Squamous cell carcinoma, head and neck	Enrichment	EGFR, PTEN, TNFRSF10B, TP53	6.06
21	Lacrimoauriculodentodigital syndrome 1	Enrichment	FGF10, FGFR2, FGFR3	5.80
22	Nevus, epidermal	Enrichment	FGFR3, HRAS, KRAS, NRAS	5.68
23	Noonan syndrome 3	Enrichment	HRAS, KRAS, RAF1, SOS1	5.64
24	Lung cancer	Enrichment	CASP8, CHEK2, EGFR, FAS, FASLG, MET	5.57
25	Langerhans cell histiocytosis	Enrichment	BRAF, MAP2K1, NRAS	5.30
26	Melanocytic nevus syndrome, congenital	Enrichment	BRAF, HRAS, NRAS, RAF1	5.24
27	Glioma	Enrichment	FGFR2, NTRK3, PTEN	5.09
28	Lung sarcomatoid carcinoma	Enrichment	KRAS, TERT, TP53	5.05
29	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS, KRAS, NRAS	5.02
30	Arteriovenous malformations of the brain	Enrichment	BRAF, EGFR, IL6, KRAS, TIMP3	4.85
31	Primary hypereosinophilic syndrome	Enrichment	FGFR1, PDGFRA, PDGFRB	4.81
32	Microform holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1	4.53
33	Lobar holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1	4.53
34	Testicular germ cell tumor	Enrichment	FGFR3, KIT, KITLG	4.51
35	Hoyeraal-hreidarsson syndrome	Enrichment	DKC1, TERT, TINF2	4.36
36	Breast adenocarcinoma	Enrichment	AKT1, KRAS, TP53	4.36
37	Lung squamous cell carcinoma	Enrichment	EGFR, FGFR3, KRAS	4.36
38	Breast cancer	Enrichment	AKT1, ATM, CASP8, CHEK2, IL2, PTEN, TP53	4.33
39	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	ITGA2, ITGA2B, ITGB3	4.33
40	Semilobar holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1	4.31
41	Normosmic congenital hypogonadotropic hypogonadism	Enrichment	FGF17, FGF8, FGFR1, GNRH1	4.31
42	Juvenile myelomonocytic leukemia	Enrichment	CBL, KRAS, NRAS, RRAS	4.20
43	Dyskeratosis congenita	Enrichment	DKC1, POT1, TERT, TINF2	4.01
44	Hepatocellular carcinoma	Enrichment	CASP8, IGF2R, MET, TP53	3.95
45	Loeys-dietz syndrome	Enrichment	TGFB2, TGFB3, TGFBR1	3.90
46	Adult hepatocellular carcinoma	Enrichment	CASP8, EGF, TP53	3.90
47	Endometrial cancer	Enrichment	ATM, CHEK2, FGFR2, PTEN	3.89
48	Kallmann syndrome	Enrichment	FGF17, FGF8, FGFR1, SEMA3A	3.87
49	Cervical cancer	Enrichment	FGFR3, TP53	3.86
50	Pfeiffer syndrome	Enrichment	FGFR1, FGFR2	3.86
51	Jackson-weiss syndrome	Enrichment	FGFR1, FGFR2	3.86
52	Loeys-dietz syndrome 4	Enrichment	TGFB2, TGFB3	3.86
53	Cervix carcinoma	Enrichment	FGFR3, TP53	3.86
54	Li-fraumeni syndrome 1	Enrichment	CHEK2, TP53	3.79
55	Sarcoma	Enrichment	CHEK2, TP53	3.79
56	Thyroid cancer, nonmedullary, 2	Enrichment	BRAF, HRAS, NRAS	3.77
57	Follicular thyroid carcinoma	Enrichment	BRAF, HRAS, NRAS	3.77
58	Encephalocraniocutaneous lipomatosis	Enrichment	FGFR1, KRAS	3.76
59	Marfan syndrome	Enrichment	LTBP2, TGFB2, TGFBR1	3.75
60	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS, NRAS	3.74
61	Gastric cancer	Enrichment	ATM, CHEK2, FGFR2, PTEN, TP53	3.68
62	Hereditary breast carcinoma	Enrichment	AKT1, ATM, CHEK2, PTEN, TP53	3.64
63	Angioma, tufted	Enrichment	GNA14, KDR	3.60
64	Leukemia, chronic lymphocytic	Enrichment	ATM, POT1, TP53	3.60
65	Pigmented nodular adrenocortical disease, primary, 1	Enrichment	GNAS, PRKAR1A	3.58
66	Tessadori-bicknell-van haaften neurodevelopmental syndrome 1	Enrichment	H4C1, H4C3	3.55
67	Tessadori-bicknell-van haaften neurodevelopmental syndrome 2	Enrichment	H4C1, H4C11	3.55
68	Bryant-li-bhoj neurodevelopmental syndrome 2	Enrichment	H3-3A, H3-3B	3.55
69	Inherited cancer-predisposing syndrome	Enrichment	ATM, CHEK2, EGFR, KIT, MET, PDGFRA, PTEN, TP53	3.54
70	Pulmonic stenosis	Enrichment	BRAF, SOS1	3.53
71	Ectodermal dysplasia and immune deficiency	Enrichment	IKBKG, NFKBIA	3.53
72	Uterine corpus cancer	Enrichment	ATM, CHEK2, PTEN	3.51
73	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB, ACTG1	3.46
74	Crouzon syndrome	Enrichment	FGFR2, FGFR3	3.39
75	Psoriatic arthritis	Enrichment	LTA, TNF	3.39
76	Testicular germ cell cancer	Enrichment	FGFR3, KIT	3.39
77	Meningioma	Enrichment	AKT1, PDGFB, PTEN	3.39
78	Prostate cancer	Enrichment	ATM, CHEK2, PTEN, TP53	3.33
79	Osteogenic sarcoma	Enrichment	CHEK2, TP53	3.32
80	Adenocarcinoma	Enrichment	ATM, TP53	3.32
81	Laryngeal squamous cell carcinoma	Enrichment	PTEN, TNFRSF10B	3.32
82	Bone osteosarcoma	Enrichment	CHEK2, TP53	3.32
83	Pancreatic cancer	Enrichment	ATM, CDKN2A, CHEK2, TP53	3.32
84	Squamous cell carcinoma	Enrichment	RB1, TP53	3.29
85	Bleeding disorder, platelet-type, 16	Enrichment	ITGA2B, ITGB3	3.27
86	Large congenital melanocytic nevus	Enrichment	HRAS, NRAS	3.27
87	Primary hyperaldosteronism	Enrichment	BRAF, CACNA1H, GNAS	3.24
88	Septopreoptic holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1	3.19
89	Midline interhemispheric variant of holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1	3.19
90	Spermatocytoma	Enrichment	FGFR3, HRAS	3.13
91	Anastomosing haemangioma	Enrichment	GNA11, GNA14	3.13
92	Brachydactyly, type a2	Enrichment	BMP2, GDF5	3.09
93	Autoimmune lymphoproliferative syndrome	Enrichment	FAS, FASLG	3.09
94	Saethre-chotzen syndrome	Enrichment	FGFR2, FGFR3	3.09
95	Multiple synostoses syndrome	Enrichment	GDF5, GDF6	3.09
96	Tessadori-bicknell-van haaften neurodevelopmental syndrome 4	Enrichment	H4C1, H4C9	3.07
97	Tessadori-bicknell-van haaften neurodevelopmental syndrome 3	Enrichment	H4C1, H4C5	3.07
98	Nasopharyngeal carcinoma	Enrichment	NFKBIA, TP53	3.06
99	Primary ovarian insufficiency	Enrichment	BMP6, CHEK2, IGF2R, KDR, NTRK1	3.04
100	Alobar holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1	3.02
101	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	AKT3, PIK3R2	3.02
102	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	AKT3, PIK3R2	3.02
103	Small cell cancer of the lung	Enrichment	RB1, TP53	2.99
104	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	ABL1, KRAS	2.99
105	Neurodevelopmental disorder with hypotonia, language delay, and skeletal defects with or without seizures	Enrichment	CACNA1A, CACNA1C	2.95
106	T-b+ severe combined immunodeficiency due to cd3delta/cd3epsilon/cd3zeta	Enrichment	CD247, CD3E	2.95
107	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	ACTA2, MYLK, TGFB2, TGFB3, TGFBR1	2.89
108	Hemifacial hyperplasia	Enrichment	FGFR2, FGFR3	2.87
109	Insulin-like growth factor i	Enrichment	IGF1, IGF1R	2.87
110	Ventricular septal defect 1	Enrichment	BMP2, BMP7	2.87
111	Holoprosencephaly	Enrichment	FGF8, FGFR1	2.87
112	Familial cerebral saccular aneurysm	Enrichment	ANGPTL6, TGFBR3	2.87
113	Achromatopsia 4	Enrichment	GNAI3, GNAT2	2.83
114	Brugada syndrome	Enrichment	CACNA1C, CACNA2D1, CACNB2, SEMA3A	2.81
115	Acute megakaryocytic leukemia	Enrichment	PTEN, TP53	2.80
116	Hemimegalencephaly	Enrichment	AKT3, PTEN	2.80
117	Diffuse large b-cell lymphoma	Enrichment	CHEK2, PTEN, TP53	2.77
118	Noonan syndrome with multiple lentigines	Enrichment	BRAF, RAF1	2.76
119	Leukemia, acute myeloid	Enrichment	KIT, KRAS, TERT, TP53	2.73
120	Atrial septal defect 1	Enrichment	BMP2, TGFB2	2.70
121	Holoprosencephaly 1	Enrichment	FGF8, FGFR1	2.70
122	Hemangioma, capillary infantile	Enrichment	FLT4, KDR	2.70
123	Megacystis-microcolon-intestinal hypoperistalsis syndrome 1	Enrichment	ACTG2, MYLK	2.69
124	Myeloma, multiple	Enrichment	CREBBP, FGFR3, KRAS, PIK3R2, RXRA	2.68
125	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	CRKL, MAPK1	2.65
126	Cowden syndrome 1	Enrichment	EGFR, PTEN	2.63
127	Dyskeratosis congenita, autosomal dominant 1	Enrichment	TERT, TINF2	2.60
128	Adrenocortical carcinoma	Enrichment	TERT, TP53	2.60
129	Hepatoblastoma	Enrichment	FGFR3, TERT, TP53	2.60
130	Hemihyperplasia, isolated	Enrichment	IGF2, RHOA	2.58
131	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	ITGA6, ITGB4	2.58
132	Gastrointestinal stromal tumor	Enrichment	KIT, PDGFRA	2.56
133	Neuropathy, hereditary sensory and autonomic, type v	Enrichment	NGF, NTRK1	2.56
134	Essential thrombocythemia	Enrichment	THPO, TP53	2.56
135	Renal cell carcinoma, papillary, 1	Enrichment	ATM, MET	2.49
136	Visceral myopathy 1	Enrichment	ACTG2, MYLK	2.48
137	Leukemia, chronic myeloid	Enrichment	ABL1, KRAS	2.46
138	Dyskeratosis congenita, autosomal dominant 2	Enrichment	TERT, TINF2	2.46
139	Gallbladder cancer	Enrichment	KRAS, TP53	2.46
140	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	ABL1, TP53	2.46
141	Glanzmann thrombasthenia 1	Enrichment	ITGA2B, ITGB3	2.44
142	Basal ganglia calcification, idiopathic, 1	Enrichment	PDGFB, PDGFRB	2.44
143	Hemochromatosis, type 1	Enrichment	BMP2, BMP6	2.44
144	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	2.42
145	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	2.42
146	Severe combined immunodeficiency	Enrichment	CD247, CD3E, LCK, ZAP70	2.42
147	Type 1 diabetes mellitus	Enrichment	IL6, INS	2.37
148	46,xy disorder of sex development	Enrichment	FGFR3, INSR	2.37
149	Inflammatory bowel disease 25, autosomal recessive	Enrichment	RIPK1, TGFB1	2.37
150	Il10-related early-onset inflammatory bowel disease	Enrichment	RIPK1, TGFB1	2.37
151	Undetermined early-onset epileptic encephalopathy	Enrichment	CACNA1A, CACNA1B, CACNA2D1, FGF12, NTRK2	2.33
152	Typical nemaline myopathy	Enrichment	ACTA1, CFL2	2.31
153	Capillary malformation-arteriovenous malformation 1	Enrichment	KRAS, MAP2K1	2.28
154	Hereditary breast ovarian cancer syndrome	Enrichment	ATM, CHEK2, PTEN, TP53	2.28
155	Colonic benign neoplasm	Enrichment	ATM, CHEK2	2.26
156	Cowden syndrome	Enrichment	AKT1, PTEN	2.26
157	Junctional epidermolysis bullosa	Enrichment	ITGA6, ITGB4	2.21
158	Renal agenesis, bilateral	Enrichment	FGF20, ITGA8	2.21
159	Lynch syndrome 1	Enrichment	ATM, CHEK2	2.17
160	Melanoma	Enrichment	CHEK2, PTEN	2.17
161	Cerebral palsy	Enrichment	CACNA1A, CACNA1C, GNB1, PDGFRB	2.16
162	Glioma susceptibility 1	Enrichment	H3-3A, H3C1	2.13
163	Inflammatory bowel disease 1	Enrichment	IL6, PRKCQ	2.13
164	Autosomal dominant macrothrombocytopenia	Enrichment	ITGA2B, ITGB3	2.12
165	Meningioma, familial	Enrichment	PDGFB, PTEN	2.08
166	Familial colorectal cancer type x	Enrichment	ATM, CHEK2	2.08
167	Renal hypodysplasia/aplasia 3	Enrichment	BMP4, FGFR3	2.08
168	Body mass index quantitative trait locus 11	Enrichment	ADCY3, BDNF, GNAS, PPARG	2.06
169	Charge syndrome	Enrichment	EP300, TNFRSF1A	2.06
170	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	2.06
171	Arteriovenous malformation	Enrichment	HRAS, MAP2K1	2.06
172	Trichothiodystrophy	Enrichment	GTF2E2, GTF2H5	2.02
173	Congenital stationary night blindness	Enrichment	CACNA1F, CACNA2D4, GNB3	2.01
174	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS, MAP2K1	1.97
175	Cleft lip/palate	Enrichment	BMP4, PDGFRA	1.95
176	Breast-ovarian cancer, familial 1	Enrichment	ATM, CHEK2	1.94
177	Nk-cell enteropathy	Enrichment	CHEK2, IGF1R	1.94
178	Periodic fever, familial, autosomal dominant	Enrichment	TNFRSF1A	1.93
179	Hypochondroplasia	Enrichment	FGFR3	1.93
180	Proteus syndrome	Enrichment	AKT1	1.93
181	Beare-stevenson cutis gyrata syndrome	Enrichment	FGFR2	1.93
182	Osteoglophonic dysplasia	Enrichment	FGFR1	1.93
183	Thanatophoric dysplasia, type i	Enrichment	FGFR3	1.93
184	Microspherophakia and/or megalocornea, with ectopia lentis and with or without secondary glaucoma	Enrichment	LTBP2	1.93
185	Trigonocephaly 1	Enrichment	FGFR1	1.93
186	Spinocerebellar ataxia 27a	Enrichment	FGF14	1.93
187	Muenke syndrome	Enrichment	FGFR3	1.93
188	Premature aging syndrome, penttinen type	Enrichment	PDGFRB	1.93
189	Type 1 diabetes mellitus 10	Enrichment	IL2RA	1.93
190	Lymphoproliferative syndrome, x-linked, 2	Enrichment	XIAP	1.93
191	Hypomagnesemia 4, renal	Enrichment	EGF	1.93
192	Glaucoma 3, primary congenital, d	Enrichment	LTBP2	1.93
193	Microphthalmia, isolated 4	Enrichment	GDF6	1.93
194	Angel-shaped phalangoepiphyseal dysplasia	Enrichment	GDF5	1.93
195	Caspase 8 deficiency	Enrichment	CASP8	1.93
196	Leprosy 4	Enrichment	LTA	1.93
197	Hypereosinophilic syndrome, idiopathic	Enrichment	PDGFRA	1.93
198	Deafness, autosomal recessive 39	Enrichment	HGF	1.93
199	Mastocytosis, cutaneous	Enrichment	KIT	1.93
200	Scaphocephaly, maxillary retrusion, and impaired intellectual development	Enrichment	FGFR2	1.93
201	Apert syndrome	Enrichment	FGFR2	1.93
202	Basal ganglia calcification, idiopathic, 5	Enrichment	PDGFB	1.93
203	Hyperpigmentation with or without hypopigmentation, familial progressive	Enrichment	KITLG	1.93
204	Multiple self-healing squamous epithelioma	Enrichment	TGFBR1	1.93
205	Myofibromatosis, infantile, 1	Enrichment	PDGFRB	1.93
206	Thanatophoric dysplasia, type ii	Enrichment	FGFR3	1.93
207	Hypogonadotropic hypogonadism 20 with or without anosmia	Enrichment	FGF17	1.93
208	Ciliary dyskinesia, primary, 33	Enrichment	DRC4	1.93
209	Gist-plus syndrome	Enrichment	PDGFRA	1.93
210	Camptodactyly, tall stature, and hearing loss syndrome	Enrichment	FGFR3	1.93
211	Ataxia-oculomotor apraxia 3	Enrichment	PIK3R5	1.93
212	Hypogonadotropic hypogonadism 23 with or without anosmia	Enrichment	LHB	1.93
213	Aplasia of lacrimal and salivary glands	Enrichment	FGF10	1.93
214	Bent bone dysplasia syndrome 1	Enrichment	FGFR2	1.93
215	Weill-marchesani syndrome 3	Enrichment	LTBP2	1.93
216	Developmental and epileptic encephalopathy 58	Enrichment	NTRK2	1.93
217	Multiple synostoses syndrome 4	Enrichment	GDF6	1.93
218	Intellectual developmental disorder, x-linked 110	Enrichment	FGF13	1.93
219	Spinocerebellar ataxia 27b, late-onset	Enrichment	FGF14	1.93
220	Hyperemesis gravidarum	Enrichment	GDF15	1.93
221	Amegakaryocytic thrombocytopenia, congenital, 2	Enrichment	THPO	1.93
222	Deafness, autosomal recessive 125	Enrichment	GAS2	1.93
223	Short syndrome	Enrichment	PIK3R1	1.93
224	Bone marrow failure syndrome 5	Enrichment	TP53	1.93
225	Hereditary lymphedema id	Enrichment	VEGFC	1.93
226	Osteofibrous dysplasia	Enrichment	MET	1.93
227	Papilloma of choroid plexus	Enrichment	TP53	1.93
228	Microphthalmia, syndromic 6	Enrichment	BMP4	1.93
229	Basal cell carcinoma 7	Enrichment	TP53	1.93
230	Myeloid and lymphoid neoplasms associated with pdgfra rearrangement	Enrichment	PDGFRA	1.93
231	Anaplastic thyroid carcinoma	Enrichment	TP53	1.93
232	Developmental and epileptic encephalopathy 90	Enrichment	FGF13	1.93
233	Orofacial cleft 11	Enrichment	BMP4	1.93
234	Metacarpal 4-5 fusion	Enrichment	FGF16	1.93
235	Lymphatic malformation 4	Enrichment	VEGFC	1.93
236	Lacrimoauriculodentodigital syndrome 3	Enrichment	FGF10	1.93
237	Familial isolated trichomegaly	Enrichment	FGF5	1.93
238	Deafness, autosomal recessive 97	Enrichment	MET	1.93
239	Skin/hair/eye pigmentation, variation in, 7	Enrichment	KITLG	1.93
240	Crouzon syndrome with acanthosis nigricans	Enrichment	FGFR3	1.93
241	Camurati-engelmann disease 2	Enrichment	TGFB2	1.93
242	Geleophysic dysplasia 3	Enrichment	LTBP3	1.93
243	Autism 9	Enrichment	MET	1.93
244	Glaucoma 1, open angle, o	Enrichment	NTF4	1.93
245	Iron overload	Enrichment	BMP6	1.93
246	Basal ganglia calcification, idiopathic, 4	Enrichment	PDGFRB	1.93
247	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	1.93
248	Hypogonadotropic hypogonadism 12 with or without anosmia	Enrichment	GNRH1	1.93
249	Multiple sclerosis 5	Enrichment	TNFRSF1A	1.93
250	Immunodeficiency 90 with encephalopathy, functional hyposplenia, and hepatic dysfunction	Enrichment	FADD	1.93
251	Hypogonadotropic hypogonadism 16 with or without anosmia	Enrichment	SEMA3A	1.93
252	Leber congenital amaurosis 17	Enrichment	GDF6	1.93
253	Cowden syndrome 6	Enrichment	AKT1	1.93
254	Telangiectasia, hereditary hemorrhagic, type 5	Enrichment	GDF2	1.93
255	Hereditary thrombocytosis with transverse limb defect	Enrichment	THPO	1.93
256	Myeloid and lymphoid neoplasms associated with pdgfrb rearrangement	Enrichment	PDGFRB	1.93
257	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	1.93
258	Hypogonadotropic hypogonadism 6 with or without anosmia	Enrichment	FGF8	1.93
259	Obesity, hyperphagia, and developmental delay	Enrichment	NTRK2	1.93
260	Achondroplasia, severe, with developmental delay and acanthosis nigricans	Enrichment	FGFR3	1.93
261	Ductal carcinoma in situ	Enrichment	TP53	1.93
262	Kosaki overgrowth syndrome	Enrichment	PDGFRB	1.93
263	Tumoral calcinosis, hyperphosphatemic, familial, 2	Enrichment	FGF23	1.93
264	Hartsfield syndrome	Enrichment	FGFR1	1.93
265	Congenital heart defects, multiple types, 7	Enrichment	FLT4	1.93
266	Loeys-dietz syndrome 5	Enrichment	TGFB3	1.93
267	Renal hypodysplasia/aplasia 2	Enrichment	FGF20	1.93
268	Tnf receptor-associated periodic fever syndrome	Enrichment	TNFRSF1A	1.93
269	20p12.3 microdeletion syndrome	Enrichment	BMP2	1.93
270	Cutis laxa, autosomal recessive, type iie	Enrichment	LTBP1	1.93
271	Short stature, facial dysmorphism, and skeletal anomalies with or without cardiac anomalies 1	Enrichment	BMP2	1.93
272	Developmental and epileptic encephalopathy 47	Enrichment	FGF12	1.93
273	Ocular pterygium-digital keloid dysplasia syndrome	Enrichment	PDGFRB	1.93
274	Chronic mast cell leukemia	Enrichment	KIT	1.93
275	Premature ovarian failure 14	Enrichment	GDF9	1.93
276	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	1.93
277	Tufted angioma of skin	Enrichment	KDR	1.93
278	Deafness, autosomal dominant 69	Enrichment	KITLG	1.93
279	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	1.93
280	Thrombocytopenia 9	Enrichment	THPO	1.93
281	Arthrogryposis, distal, type 11	Enrichment	MET	1.93
282	Lacrimoauriculodentodigital syndrome 2	Enrichment	FGFR3	1.93
283	Short-rib thoracic dysplasia 22 without polydactyly	Enrichment	FGF4	1.93
284	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	1.93
285	Glaucoma secondary to spherophakia/ectopia lentis and megalocornea	Enrichment	LTBP2	1.93
286	Isolated bone marrow mastocytosis	Enrichment	KIT	1.93
287	Smoldering systemic mastocytosis	Enrichment	KIT	1.93
288	Choroid plexus cancer	Enrichment	TP53	1.93
289	Spinocerebellar ataxia type 27b	Enrichment	FGF14	1.93
290	Fgfr3-related chondrodysplasia	Enrichment	FGFR3	1.93
291	Mastocytosis	Enrichment	KIT	1.93
292	Congenital primary lymphedema of gordon	Enrichment	VEGFC	1.93
293	Camptodactyly-tall stature-scoliosis-hearing loss syndrome	Enrichment	FGFR3	1.93
294	Familial progressive hyperpigmentation	Enrichment	KITLG	1.93
295	Pleomorphic xanthoastrocytoma	Enrichment	TP53	1.93
296	Cutaneous mastocytoma	Enrichment	KIT	1.93
297	Typical urticaria pigmentosa	Enrichment	KIT	1.93
298	Nodular urticaria pigmentosa	Enrichment	KIT	1.93
299	Hartsfield-bixler-demyer syndrome	Enrichment	FGFR1	1.93
300	Pseudoxanthomatous diffuse cutaneous mastocytosis	Enrichment	KIT	1.93
301	Telangiectasia macularis eruptiva perstans	Enrichment	KIT	1.93
302	Acute mast cell leukemia	Enrichment	KIT	1.93
303	Egf-related primary hypomagnesemia with intellectual disability	Enrichment	EGF	1.93
304	Non-syndromic unicoronal craniosynostosis	Enrichment	FGFR2	1.93
305	Familial progressive hyper- and hypopigmentation	Enrichment	KITLG	1.93
306	Plaque-form urticaria pigmentosa	Enrichment	KIT	1.93
307	Interstitial lung disease specific to childhood	Enrichment	FGF10	1.93
308	Bullous diffuse cutaneous mastocytosis	Enrichment	KIT	1.93
309	Testis seminoma	Enrichment	KIT	1.93
310	Specific learning disability	Enrichment	RPS6KA3, YWHAG	1.90
311	Non-immune hydrops fetalis	Enrichment	FLT4, HRAS, KRAS	1.90
312	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	1.89
313	Vacterl association with hydrocephalus	Enrichment	PTEN	1.89
314	Seckel syndrome 1	Enrichment	ATR	1.89
315	Accelerated tumor formation	Enrichment	MDM2	1.89
316	Lessel-kubisch syndrome	Enrichment	MDM2	1.89
317	Papillary tumor of the pineal region	Enrichment	PTEN	1.89
318	Tumor predisposition syndrome 4	Enrichment	CHEK2	1.89
319	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Enrichment	AKT3	1.89
320	Thrombocytopenia 4	Enrichment	CYCS	1.89
321	Cutaneous telangiectasia and cancer syndrome, familial	Enrichment	ATR	1.89
322	Olmsted syndrome 2	Enrichment	PERP	1.89
323	Endometrial serous adenocarcinoma	Enrichment	ATM	1.89
324	Glioma susceptibility 2	Enrichment	PTEN	1.89
325	Leiomyosarcoma	Enrichment	CHEK2	1.89
326	Erythrokeratodermia variabilis et progressiva 7	Enrichment	PERP	1.89
327	Capillary hemangioma	Enrichment	AKT3	1.89
328	Oocyte/zygote/embryo maturation arrest 21	Enrichment	CHEK1	1.89
329	B-cell non-hodgkin lymphoma	Enrichment	ATM	1.89
330	Familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome	Enrichment	ATR	1.89
331	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	Enrichment	PTEN	1.89
332	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	1.89
333	Hydrocephalus	Enrichment	FGFR2, PDGFRB	1.89
334	Oculoectodermal syndrome	Enrichment	KRAS	1.88
335	Spinocerebellar ataxia 12	Enrichment	PPP2R2B	1.88
336	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	1.88
337	Tumor predisposition syndrome 3	Enrichment	POT1	1.88
338	Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development	Enrichment	PTPA	1.88
339	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 8	Enrichment	POT1	1.88
340	Houge-janssens syndrome 4	Enrichment	PPP2R5C	1.88
341	Cataracts, hearing impairment, nephrotic syndrome, and enterocolitis 1	Enrichment	DKC1	1.88
342	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	1.88
343	Houge-janssens syndrome 2	Enrichment	PPP2R1A	1.88
344	Spinocerebellar ataxia 14	Enrichment	PRKCG	1.88
345	High-grade astrocytoma with piloid features	Enrichment	POT1	1.88
346	Cerebroretinal microangiopathy with calcifications and cysts 3	Enrichment	POT1	1.88
347	Autosomal recessive dyskeratosis congenita 4	Enrichment	TERT	1.88
348	Trilateral retinoblastoma	Enrichment	RB1	1.88
349	Congenital pulmonary airway malformation	Enrichment	KRAS	1.88
350	Ppp2r1a-related neurodevelopmental disorder	Enrichment	PPP2R1A	1.88
351	Lung oat cell carcinoma	Enrichment	RB1	1.88
352	Systemic lupus erythematosus 6	Enrichment	ITGAM	1.87
353	Melanosis, neurocutaneous	Enrichment	NRAS	1.87
354	Noonan syndrome 6	Enrichment	NRAS	1.87
355	Noonan syndrome 11	Enrichment	MRAS	1.87
356	Angioedema, hereditary, 4	Enrichment	PLG	1.87
357	Noonan syndrome 13	Enrichment	MAPK1	1.87
358	Fetomaternal alloimmune thrombocytopenia 2	Enrichment	ITGA2B	1.87
359	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	1.87
360	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	1.87
361	Immunodeficiency 129	Enrichment	RHOH	1.87
362	Amelogenesis imperfecta, type ih	Enrichment	ITGB6	1.87
363	T-cell immunodeficiency with epidermodysplasia verruciformis	Enrichment	RHOH	1.87
364	Fetomaternal alloimmune thrombocytopenia 3	Enrichment	ITGA2	1.87
365	Immune dysregulation, neurodevelopmental defects, and colitis	Enrichment	ITGAV	1.87
366	Phakomatosis pigmentokeratotica	Enrichment	HRAS	1.87
367	Neurocutaneous melanocytosis	Enrichment	NRAS	1.87
368	Osteopetrosis and infantile neuroaxonal dystrophy	Enrichment	PLA2G6	1.84
369	Fleck retina, familial benign	Enrichment	PLA2G5	1.84
370	Neurodegeneration with brain iron accumulation 2a	Enrichment	PLA2G6	1.84
371	Parkinson-dementia syndrome	Enrichment	MAPT	1.84
372	Supranuclear palsy, progressive, 1	Enrichment	MAPT	1.84
373	Progressive supranuclear palsy	Enrichment	MAPT	1.84
374	Autoimmune lymphoproliferative syndrome, type iia	Enrichment	CASP10	1.84
375	Parkinson disease 14, autosomal recessive	Enrichment	PLA2G6	1.84
376	Cerebral amyloid angiopathy, app-related	Enrichment	APP	1.84
377	Neurodegeneration with brain iron accumulation 2b	Enrichment	PLA2G6	1.84
378	Cytosolic phospholipase-a2 alpha deficiency associated bleeding disorder	Enrichment	PLA2G4A	1.84
379	Developmental and epileptic encephalopathy 56	Enrichment	YWHAG	1.84
380	Platelet-activating factor acetylhydrolase deficiency	Enrichment	PLA2G7	1.84
381	Gastrointestinal ulceration, recurrent, with dysfunctional platelets	Enrichment	PLA2G4A	1.84
382	Classic progressive supranuclear palsy syndrome	Enrichment	MAPT	1.84
383	Intellectual developmental disorder, autosomal recessive 80, with variant lissencephaly	Enrichment	CASP2	1.84
384	Atypical progressive supranuclear palsy syndrome	Enrichment	MAPT	1.84
385	Cryptogenic multifocal ulcerous stenosing enteritis	Enrichment	PLA2G4A	1.84
386	Distal 17p13.3 microdeletion syndrome	Enrichment	YWHAE	1.84
387	Familial benign flecked retina	Enrichment	PLA2G5	1.84
388	Heritable pulmonary arterial hypertension	Enrichment	EIF2AK4, GDF2	1.83
389	Immune deficiency disease	Enrichment	ATM, RIPK1	1.83
390	Alzheimer's disease	Enrichment	APP, MAPT	1.83
391	Charcot-marie-tooth disease, x-linked recessive, 5	Enrichment	PRPS1	1.82
392	Coffin-lowry syndrome	Enrichment	RPS6KA3	1.82
393	Arts syndrome	Enrichment	PRPS1	1.82
394	Parkinson disease 13, autosomal dominant	Enrichment	HTRA2	1.82
395	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 2	Enrichment	SLC25A4	1.82
396	Mitochondrial dna depletion syndrome 12b , autosomal recessive	Enrichment	SLC25A4	1.82
397	Phosphoribosylpyrophosphate synthetase superactivity	Enrichment	PRPS1	1.82
398	Deafness, x-linked 1	Enrichment	PRPS1	1.82
399	Intellectual developmental disorder, x-linked 19	Enrichment	RPS6KA3	1.82
400	Mitochondrial dna depletion syndrome 12a , autosomal dominant	Enrichment	SLC25A4	1.82
401	Mitochondrial metabolism disease	Enrichment	SLC25A4	1.82
402	Congenital heart defects and ectodermal dysplasia	Enrichment	PRKD1	1.82
403	Cdkn2a cancer predisposition	Enrichment	CDKN2A	1.82
404	Symptomatic form of coffin-lowry syndrome in female carriers	Enrichment	RPS6KA3	1.82
405	X-linked intellectual disability-limb spasticity-retinal dystrophy-diabetes insipidus syndrome	Enrichment	PRPS1	1.82
406	Malignant epithelial tumor of salivary glands	Enrichment	PRKD1	1.82
407	Renal cell carcinoma, nonpapillary	Enrichment	ATM, MET	1.82
408	Wilms tumor 1	Enrichment	CHEK2, IGF2	1.82
409	Hypocalciuric hypercalcemia, familial, type ii	Enrichment	GNA11	1.80
410	Deafness, autosomal recessive 26	Enrichment	GAB1	1.80
411	Pseudohypoparathyroidism, type ic	Enrichment	GNAS	1.80
412	Osseous heteroplasia, progressive	Enrichment	GNAS	1.80
413	Neurodevelopmental disorder with involuntary movements	Enrichment	GNAO1	1.80
414	Ventricular tachycardia, familial	Enrichment	GNAI2	1.80
415	Acth-independent macronodular adrenal hyperplasia 1	Enrichment	GNAS	1.80
416	Neurodevelopmental disorder with hypotonia and dysmorphic facies	Enrichment	GNB2	1.80
417	Stuve-wiedemann syndrome 2	Enrichment	IL6ST	1.80
418	Hyper-ige syndrome 4a, autosomal dominant, with recurrent infections	Enrichment	IL6ST	1.80
419	Pituitary adenoma 3, multiple types	Enrichment	GNAS	1.80
420	Pseudohypoaldosteronism, type iic	Enrichment	WNK1	1.80
421	Neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language	Enrichment	MEF2C	1.80
422	Neurodevelopmental disorder with hypotonia, impaired speech, and behavioral abnormalities	Enrichment	GNAI1	1.80
423	Developmental and epileptic encephalopathy 17	Enrichment	GNAO1	1.80
424	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	1.80
425	Coronary artery disease, autosomal dominant, 1	Enrichment	MEF2A	1.80
426	Night blindness, congenital stationary, autosomal dominant 3	Enrichment	GNAT1	1.80
427	Dystonia 25	Enrichment	GNAL	1.80
428	Night blindness, congenital stationary, type 1g	Enrichment	GNAT1	1.80
429	Hypocalcemia, autosomal dominant 2	Enrichment	GNA11	1.80
430	Charcot-marie-tooth disease, dominant intermediate f	Enrichment	GNB4	1.80
431	Disorders of gnas inactivation	Enrichment	GNAS	1.80
432	Thrombocytopenia 6	Enrichment	SRC	1.80
433	Hyper-ige syndrome 4b, autosomal recessive, with recurrent infections	Enrichment	IL6ST	1.80
434	Immunodeficiency 94 with autoinflammation and dysmorphic facies	Enrichment	IL6ST	1.80
435	Intellectual developmental disorder, autosomal dominant 42	Enrichment	GNB1	1.80
436	Sick sinus syndrome 4	Enrichment	GNB2	1.80
437	5q14.3 microdeletion syndrome	Enrichment	MEF2C	1.80
438	Cerebral cavernous malformations 5	Enrichment	MAP3K3	1.80
439	Complete atrioventricular septal defect without ventricular hypoplasia	Enrichment	MEF2C	1.80
440	Monostotic fibrous dysplasia	Enrichment	GNAS	1.80
441	Gnao1-related disorder	Enrichment	GNAO1	1.80
442	Mef2c-related disorder	Enrichment	MEF2C	1.80
443	Phakomatosis cesiomarmorata	Enrichment	GNA11	1.80
444	Verrucous hemangioma	Enrichment	MAP3K3	1.80
445	Kaposiform hemangioendothelioma	Enrichment	GNA14	1.80
446	Mazabraud syndrome	Enrichment	GNAS	1.80
447	Acrodysostosis 1 with or without hormone resistance	Enrichment	PRKAR1A	1.79
448	Cardiospondylocarpofacial syndrome	Enrichment	MAP3K7	1.79
449	Noonan syndrome 5	Enrichment	RAF1	1.79
450	Noonan syndrome 4	Enrichment	SOS1	1.79
451	Carney complex, type 1	Enrichment	PRKAR1A	1.79
452	Melorheostosis, isolated	Enrichment	MAP2K1	1.79
453	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	1.79
454	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	1.79
455	Noonan syndrome 9	Enrichment	SOS2	1.79
456	Deafness, autosomal recessive 44	Enrichment	ADCY1	1.79
457	Frontometaphyseal dysplasia 2	Enrichment	MAP3K7	1.79
458	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	1.79
459	Myxoma, intracardiac	Enrichment	PRKAR1A	1.79
460	Melorheostosis	Enrichment	MAP2K1	1.79
461	Leopard syndrome 2	Enrichment	RAF1	1.79
462	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	1.79
463	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	1.79
464	Menke-hennekam syndrome 1	Enrichment	CREBBP	1.79
465	Trigonitis	Enrichment	RAF1	1.79
466	Pparg-associated congenital generalized lipodystrophy	Enrichment	PPARG	1.79
467	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	1.79
468	Prkar1b-related neurodegenerative dementia with intermediate filaments	Enrichment	PRKAR1B	1.79
469	Menke-hennekam syndrome	Enrichment	CREBBP	1.79
470	Autosomal dominant non-syndromic intellectual disability	Enrichment	CACNA1I, CACNG2, ERBB4, GNB1	1.78
471	Intellectual developmental disorder, x-linked, syndromic 33	Enrichment	TAF1	1.77
472	Dystonia 3, torsion, x-linked	Enrichment	TAF1	1.77
473	Neurodevelopmental disorder with feeding difficulties, thin corpus callosum, and foot deformity	Enrichment	TAF2	1.77
474	Trichothiodystrophy 6, nonphotosensitive	Enrichment	GTF2E2	1.77
475	Microphthalmia, syndromic 12	Enrichment	RARB	1.77
476	Trichothiodystrophy 3, photosensitive	Enrichment	GTF2H5	1.77
477	Alazami-yuan syndrome	Enrichment	TAF6	1.77
478	Intellectual developmental disorder, autosomal recessive 60	Enrichment	TAF13	1.77
479	Bryant-li-bhoj neurodevelopmental syndrome 1	Enrichment	H3-3A	1.77
480	Fraser syndrome 3	Enrichment	GRIP1	1.77
481	X-linked intellectual disability-global development delay-facial dysmorphism-sacral caudal remnant syndrome	Enrichment	TAF1	1.77
482	Donohue syndrome	Enrichment	INSR	1.76
483	Pallister-killian syndrome	Enrichment	ARAF	1.76
484	Hyperinsulinemic hypoglycemia, familial, 5	Enrichment	INSR	1.76
485	Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities	Enrichment	INSR	1.76
486	Diabetes mellitus, insulin-resistant, with acanthosis nigricans	Enrichment	INSR	1.76
487	Noonan syndrome 7	Enrichment	BRAF	1.76
488	Leopard syndrome 3	Enrichment	BRAF	1.76
489	Parkinson disease 18, autosomal dominant	Enrichment	EIF4G1	1.76
490	Mehmo syndrome	Enrichment	EIF2S3	1.76
491	Leukoencephalopathy with vanishing white matter 3	Enrichment	EIF2B3	1.76
492	Leukoencephalopathy, developmental delay, and episodic neurologic regression syndrome	Enrichment	EIF2AK2	1.76
493	Autism 19	Enrichment	EIF4E	1.76
494	Leukoencephalopathy, motor delay, spasticity, and dysarthria syndrome	Enrichment	EIF2AK1	1.76
495	Lymphangioma	Enrichment	BRAF	1.76
496	Phace association	Enrichment	BRAF	1.76
497	Neurodevelopmental disorder with hypotonia and speech delay, with or without seizures	Enrichment	EIF4A2	1.76
498	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	1.76
499	Faundes-banka syndrome	Enrichment	EIF5A	1.76
500	Dystonia 33	Enrichment	EIF2AK2	1.76
501	Leukoencephalopathy with vanishing white matter 2	Enrichment	EIF2B2	1.76
502	Syringocystadenoma papilliferum	Enrichment	BRAF	1.76
503	Ganglioglioma	Enrichment	BRAF	1.76
504	Nongerminomatous germ cell tumor	Enrichment	BRAF	1.76
505	Phace syndrome	Enrichment	BRAF	1.76
506	Classic hairy cell leukemia	Enrichment	BRAF	1.76
507	Incontinentia pigmenti	Enrichment	IKBKG	1.76
508	Autoinflammatory disease, systemic, x-linked	Enrichment	IKBKG	1.76
509	Fetal encasement syndrome	Enrichment	CHUK	1.76
510	Immunodeficiency 15b	Enrichment	IKBKB	1.76
511	Immunodeficiency 15a	Enrichment	IKBKB	1.76
512	Ectodermal dysplasia and immunodeficiency 1	Enrichment	IKBKG	1.76
513	Bartsocas-papas syndrome 2	Enrichment	CHUK	1.76
514	Autoinflammation with episodic fever and lymphadenopathy	Enrichment	RIPK1	1.76
515	Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to ikbka deficiency	Enrichment	CHUK	1.76
516	Common variable immunodeficiency phenotype due to tweak deficiency	Enrichment	TNFSF12	1.76
517	Rhabdomyosarcoma	Enrichment	PTEN, TP53	1.76
518	Intellectual developmental disorder, x-linked 30	Enrichment	PAK3	1.75
519	Cardiac valvular dysplasia 1	Enrichment	PLD1	1.75
520	Neurodevelopmental disorder with absent language and variable seizures	Enrichment	WASF1	1.75
521	Knobloch syndrome 2	Enrichment	PAK2	1.75
522	Intellectual developmental disorder with macrocephaly, seizures, and speech delay	Enrichment	PAK1	1.75
523	Intellectual developmental disorder, x-linked 46	Enrichment	ARHGEF6	1.75
524	Nemaline myopathy 7	Enrichment	CFL2	1.75
525	8p11.2 deletion syndrome	Enrichment	ANK1	1.75
526	Takenouchi-kosaki syndrome	Enrichment	CDC42	1.75
527	Neurodevelopmental disorder with language delay and seizures	Enrichment	TIAM1	1.75
528	Congenital dyserythropoietic anemia type iiib	Enrichment	RACGAP1	1.75
529	Nocarh syndrome	Enrichment	CDC42	1.75
530	Anemia, congenital dyserythropoietic, type iiib, autosomal recessive	Enrichment	RACGAP1	1.75
531	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	1.75
532	Baraitser-winter syndrome 1	Enrichment	ACTB	1.73
533	Immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis	Enrichment	RAC2	1.73
534	Congenital myopathy 2a, typical, autosomal dominant	Enrichment	ACTA1	1.73
535	Amyloidosis, finnish type	Enrichment	GSN	1.73
536	Amyotrophic lateral sclerosis 18	Enrichment	PFN1	1.73
537	Myopathy, scapulohumeroperoneal	Enrichment	ACTA1	1.73
538	Nephrotic syndrome, type 8	Enrichment	ARHGDIA	1.73
539	Megacystis-microcolon-intestinal hypoperistalsis syndrome 5	Enrichment	ACTG2	1.73
540	Neurodevelopmental disorder with structural brain anomalies and dysmorphic facies	Enrichment	RAC3	1.73
541	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	1.73
542	Immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia	Enrichment	RAC2	1.73
543	Becker nevus syndrome	Enrichment	ACTB	1.73
544	Dystonia-deafness syndrome 1	Enrichment	ACTB	1.73
545	Visceral neuropathy, familial, 3, autosomal dominant	Enrichment	ACTG2	1.73
546	Congenital myopathy 2b, severe infantile, autosomal recessive	Enrichment	ACTA1	1.73
547	Autosomal dominant familial visceral neuropathy	Enrichment	ACTG2	1.73
548	Noonan syndrome-like disorder with loose anagen hair 2	Enrichment	PPP1CB	1.73
549	Congenital myopathy 2c, severe infantile, autosomal dominant	Enrichment	ACTA1	1.73
550	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	1.73
551	Immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia	Enrichment	RAC2	1.73
552	Baraitser-winter syndrome	Enrichment	ACTB	1.73
553	Zebra body myopathy	Enrichment	ACTA1	1.73
554	Infantile lad-like disease due to rac2 deficiency	Enrichment	RAC2	1.73
555	Congenital smooth muscle hamartoma	Enrichment	ACTB	1.73
556	Reticular dysgenesis-like severe combined immunodeficiency	Enrichment	RAC2	1.73
557	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	1.73
558	Actin-accumulation myopathy	Enrichment	ACTA1	1.73
559	Myopathic intestinal pseudoobstruction	Enrichment	ACTG2	1.73
560	Rac2-related combined immunodeficiency-bronchiectasis-cancer-predisposing syndrome	Enrichment	RAC2	1.73
561	Actg2 visceral myopathy	Enrichment	ACTG2	1.73
562	Hirschsprung disease 1	Enrichment	ERBB2, ERBB3, NRG3	1.73
563	Osteogenesis imperfecta, type iii	Enrichment	BMP1, SERPINF1	1.71
564	Acute promyelocytic leukemia	Enrichment	PRKAR1A, RARA	1.71
565	Anhidrosis, isolated, with normal sweat glands	Enrichment	ITPR2	1.71
566	Erythroleukemia, familial	Enrichment	ERBB3	1.71
567	Paget disease, extramammary	Enrichment	ERBB2	1.71
568	Thyrotoxic periodic paralysis 1	Enrichment	CACNA1S	1.71
569	Developmental and epileptic encephalopathy 8	Enrichment	ARHGEF9	1.71
570	Epilepsy, idiopathic generalized 9	Enrichment	CACNB4	1.71
571	Brugada syndrome 4	Enrichment	CACNB2	1.71
572	Bleeding disorder, platelet-type, 18	Enrichment	RASGRP2	1.71
573	Lethal congenital contracture syndrome 2	Enrichment	ERBB3	1.71
574	Episodic ataxia, type 5	Enrichment	CACNB4	1.71
575	Immunodeficiency 62	Enrichment	ARHGEF1	1.71
576	Immunodeficiency 64 with lymphoproliferation	Enrichment	RASGRP1	1.71
577	Visceral neuropathy, familial, 2, autosomal recessive	Enrichment	ERBB2	1.71
578	Neurodevelopmental disorder with midbrain and hindbrain malformations	Enrichment	ARHGEF2	1.71
579	Immunodeficiency 81	Enrichment	LCP2	1.71
580	Charcot-marie-tooth disease, demyelinating, type 1j	Enrichment	ITPR3	1.71
581	Neurodevelopmental disorder with speech impairment and with or without seizures	Enrichment	CACNA1I	1.71
582	Congenital myopathy 18	Enrichment	CACNA1S	1.71
583	Immunodeficiency 48	Enrichment	ZAP70	1.71
584	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	1.71
585	Thrombocytopenia 3	Enrichment	FYB1	1.71
586	Cone-rod dystrophy, x-linked, 3	Enrichment	CACNA1F	1.71
587	Retinal cone dystrophy 4	Enrichment	CACNA2D4	1.71
588	Immunodeficiency 18	Enrichment	CD3E	1.71
589	Slowed nerve conduction velocity, autosomal dominant	Enrichment	ARHGEF10	1.71
590	Primary aldosteronism, seizures, and neurologic abnormalities	Enrichment	CACNA1D	1.71
591	Immunodeficiency 25	Enrichment	CD247	1.71
592	Brugada syndrome 3	Enrichment	CACNA1C	1.71
593	Epilepsy, childhood absence 6	Enrichment	CACNA1H	1.71
594	Malignant hyperthermia 5	Enrichment	CACNA1S	1.71
595	Intellectual developmental disorder, autosomal dominant 10	Enrichment	CACNG2	1.71
596	Sinoatrial node dysfunction and deafness	Enrichment	CACNA1D	1.71
597	Thrombocytopenia 11 with multiple congenital anomalies and dysmorphic facies	Enrichment	RAP1B	1.71
598	Amyotrophic lateral sclerosis 19	Enrichment	ERBB4	1.71
599	Spinocerebellar ataxia 42	Enrichment	CACNA1G	1.71
600	Developmental and epileptic encephalopathy 110	Enrichment	CACNA2D1	1.71
601	Brain small vessel disease 5 with osteoporosis	Enrichment	ARHGEF15	1.71
602	Autoimmune disease, multisystem, infantile-onset, 2	Enrichment	ZAP70	1.71
603	Spinocerebellar ataxia 42, early-onset, severe, with neurodevelopmental deficits	Enrichment	CACNA1G	1.71
604	Immunodeficiency 22	Enrichment	LCK	1.71
605	Developmental and epileptic encephalopathy 69	Enrichment	CACNA1E	1.71
606	Hyperaldosteronism, familial, type iv	Enrichment	CACNA1H	1.71
607	Congenital autosomal recessive small-platelet thrombocytopenia	Enrichment	FYB1	1.71
608	Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy	Enrichment	ITPR3	1.71
609	Conn's syndrome	Enrichment	CACNA1H	1.71
610	Immunodeficiency 64	Enrichment	RASGRP1	1.71
611	Ebv-induced lymphoproliferative disease due to rasgrp1 deficiency	Enrichment	RASGRP1	1.71
612	Sporadic hemiplegic migraine	Enrichment	CACNA1A	1.71
613	Atypical timothy syndrome	Enrichment	CACNA1C	1.71
614	Aldosterone-producing adenoma with seizures and neurological abnormalities	Enrichment	CACNA1D	1.71
615	Timothy syndrome type 2	Enrichment	CACNA1C	1.71
616	Periodic paralysis with transient compartment-like syndrome	Enrichment	CACNA1S	1.71
617	Timothy syndrome type 1	Enrichment	CACNA1C	1.71
618	Serous carcinoma of the corpus uteri	Enrichment	ERBB2	1.71
619	Zap70-related severe combined immunodeficiency	Enrichment	ZAP70	1.71
620	Cacna1c-related disorders	Enrichment	CACNA1C	1.71
621	Benign paroxysmal torticollis of infancy	Enrichment	CACNA1A	1.71
622	Pulmonary hypertension, primary, 1	Enrichment	EIF2AK4, GDF2	1.69
623	Behcet syndrome	Enrichment	FAS, TNFRSF1A	1.69
624	Melanoma, cutaneous malignant 1	Enrichment	POT1, TERT	1.68
625	Multiple sclerosis	Enrichment	ITGB4, TNFRSF1A	1.68
626	Neural tube defects	Enrichment	ITGB1, PARD3	1.66
627	Craniosynostosis	Enrichment	FGFR2, FGFR3	1.65
628	Acromicric dysplasia	Enrichment	LTBP3	1.63
629	Cri-du-chat syndrome	Enrichment	SEMA5A	1.63
630	Lymphatic malformation 1	Enrichment	FLT4	1.63
631	Sorsby fundus dystrophy	Enrichment	TIMP3	1.63
632	Myeloproliferative disorder, chronic, with eosinophilia	Enrichment	PDGFRB	1.63
633	Adrenocortical carcinoma, hereditary	Enrichment	TP53	1.63
634	Camurati-engelmann disease 1	Enrichment	TGFB1	1.63
635	Insensitivity to pain, congenital, with anhidrosis	Enrichment	NTRK1	1.63
636	Trichomegaly	Enrichment	FGF5	1.63
637	Intracranial hypertension, idiopathic	Enrichment	FLT4	1.63
638	Kyphomelic dysplasia	Enrichment	CCN2	1.63
639	Omodysplasia 1	Enrichment	GPC6	1.63
640	Pulmonary hypoplasia, primary	Enrichment	FGF10	1.63
641	Dermatofibrosarcoma protuberans	Enrichment	PDGFB	1.63
642	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	PIK3R5	1.63
643	Immunodeficiency 41 with lymphoproliferation and autoimmunity	Enrichment	IL2RA	1.63
644	Loeys-dietz syndrome 2	Enrichment	TGFBR1	1.63
645	Parkinson disease 8, autosomal dominant	Enrichment	GDF6	1.63
646	Piebald trait	Enrichment	KIT	1.63
647	Aural atresia, congenital	Enrichment	FGFR2	1.63
648	Keratosis, seborrheic	Enrichment	FGFR3	1.63
649	Multiple synostoses syndrome 2	Enrichment	GDF5	1.63
650	Myopathy, mitochondrial progressive, with congenital cataract and developmental delay	Enrichment	GFER	1.63
651	Cutis laxa, autosomal recessive, type ic	Enrichment	LTBP4	1.63
652	Silver-russell syndrome 3	Enrichment	IGF2	1.63
653	Osteogenesis imperfecta, type xiii	Enrichment	BMP1	1.63
654	Lymphoma, hodgkin, classic	Enrichment	TP53	1.63
655	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	1.63
656	Brachydactyly, type a1, c	Enrichment	GDF5	1.63
657	Symphalangism, proximal, 1b	Enrichment	GDF5	1.63
658	Pain sensitivity quantitative trait locus 1	Enrichment	NTRK1	1.63
659	Antley-bixler syndrome without genital anomalies or disordered steroidogenesis	Enrichment	FGFR2	1.63
660	Spondyloepimetaphyseal dysplasia, li-shao-li type	Enrichment	CCN2	1.63
661	Waardenburg syndrome, type 2f	Enrichment	KITLG	1.63
662	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.63
663	Kowarski syndrome	Enrichment	GH1	1.63
664	Infantile myofibromatosis	Enrichment	PDGFRB	1.63
665	Immunodeficiency 127	Enrichment	TNF	1.63
666	Childhood hepatocellular carcinoma	Enrichment	MET	1.63
667	Split hand-foot malformation	Enrichment	FGFR2	1.63
668	Rosette-forming glioneuronal tumor	Enrichment	FGFR1	1.63
669	Papillary renal cell carcinoma	Enrichment	MET	1.63
670	Congenital mesoblastic nephroma	Enrichment	NTRK3	1.63
671	Camurati-engelmann disease	Enrichment	TGFB1	1.63
672	Congenital fibrosarcoma	Enrichment	TP53	1.63
673	Microphthalmia/coloboma 6	Enrichment	GDF6	1.63
674	Hodgkin's lymphoma	Enrichment	TP53	1.63
675	Fibrosarcoma	Enrichment	NTRK3	1.63
676	Proximal symphalangism	Enrichment	GDF5	1.63
677	Hereditary lymphedema i	Enrichment	FLT4	1.63
678	Craniosynostosis 7	Enrichment	BMP2	1.63
679	Congenital amegakaryocytic thrombocytopenia	Enrichment	THPO	1.63
680	Interfrontal craniofaciosynostosis	Enrichment	FGFR1	1.63
681	Intermittent hydrarthrosis	Enrichment	TNFRSF1A	1.63
682	Short stature due to growth hormone qualitative anomaly	Enrichment	GH1	1.63
683	Autosomal dominant nonsyndromic deafness	Enrichment	FGFR2	1.63
684	Chronic eosinophilic leukemia	Enrichment	PDGFRA	1.63
685	Growth delay due to insulin-like growth factor type 1 deficiency	Enrichment	IGF1	1.63
686	B-lymphoblastic leukemia/lymphoma with recurrent genetic abnormality	Enrichment	PDGFRA	1.63
687	B-lymphoblastic leukemia/lymphoma with t	Enrichment	KIT	1.63
688	Common variable immunodeficiency 12	Enrichment	NFKB1	1.63
689	Silver-russell syndrome due to an imprinting defect of 11p15	Enrichment	IGF2	1.63
690	Pleomorphic rhabdomyosarcoma	Enrichment	TP53	1.63
691	Oculootodental syndrome	Enrichment	FADD	1.63
692	Silver-russell syndrome due to 11p15 microduplication	Enrichment	IGF2	1.63
693	Rare genetic intellectual disability	Enrichment	CREBBP, EP300	1.62
694	Alzheimer disease, familial, 1	Enrichment	APP, MAPT	1.61
695	Congenital heart defects, multiple types, 3	Enrichment	CHEK2	1.60
696	Cardiac valvular dysplasia, x-linked	Enrichment	ATM	1.60
697	Intravascular large b-cell lymphoma	Enrichment	BCL2	1.60
698	Senior-loken syndrome 7	Enrichment	AKT3	1.60
699	High grade glioma	Enrichment	ATM	1.60
700	Bardet-biedl syndrome 16	Enrichment	AKT3	1.60
701	T-cell prolymphocytic leukemia	Enrichment	ATM	1.60
702	Vacterl with hydrocephalus	Enrichment	PTEN	1.60
703	Juvenile polyposis of infancy	Enrichment	PTEN	1.60
704	Burkitt lymphoma	Enrichment	MYC	1.58
705	Revesz syndrome	Enrichment	TINF2	1.58
706	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 1	Enrichment	TERT	1.58
707	Chromosome 13q14 deletion syndrome	Enrichment	RB1	1.58
708	Houge-janssens syndrome 1	Enrichment	PPP2R5D	1.58
709	Congenital heart defects and skeletal malformations syndrome	Enrichment	ABL1	1.58
710	Dyskeratosis congenita, autosomal dominant 3	Enrichment	TINF2	1.58
711	Oligodendroglioma	Enrichment	POT1	1.58
712	Melanoma, cutaneous malignant 9	Enrichment	TERT	1.58
713	Idiopathic interstitial pneumonia	Enrichment	TERT	1.58
714	Anaplastic oligodendroglioma	Enrichment	POT1	1.58
715	Familial retinoblastoma	Enrichment	RB1	1.58
716	Leukocyte adhesion deficiency, type i	Enrichment	ITGB2	1.57
717	Scoliosis, isolated 1	Enrichment	MAPK7	1.57
718	Costello syndrome	Enrichment	HRAS	1.57
719	Plasminogen deficiency, type i	Enrichment	PLG	1.57
720	Quebec platelet disorder	Enrichment	PLAU	1.57
721	Leukocyte adhesion deficiency, type iii	Enrichment	ITGB2	1.57
722	Epidermolysis bullosa, junctional 5a, intermediate	Enrichment	ITGB4	1.57
723	Noonan syndrome 12	Enrichment	RRAS2	1.57
724	Epidermolysis bullosa, junctional 7, with interstitial lung disease and nephrotic syndrome	Enrichment	ITGA3	1.57
725	Metaphyseal anadysplasia 2	Enrichment	MMP9	1.57
726	Hereditary angioedema	Enrichment	PLG	1.57
727	Metaphyseal anadysplasia	Enrichment	MMP9	1.57
728	Localized junctional epidermolysis bullosa, non-herlitz type	Enrichment	ITGB4	1.57
729	Wooly hair nevus	Enrichment	HRAS	1.57
730	Thrombocytopenia	Enrichment	ITGA2B, ITGB3, THPO	1.57
731	Tooth agenesis	Enrichment	FGFR1, TGFA	1.57
732	Microcephaly	Enrichment	ACTB, ACTG1, GNAO1, GNB1, IGF1R, PAK3	1.56
733	Cerebral amyloid angiopathy, cst3-related	Enrichment	APP	1.54
734	Pick disease of brain	Enrichment	MAPT	1.54
735	Infantile osteopetrosis with neuroaxonal dysplasia	Enrichment	PLA2G6	1.54
736	Melanoma-astrocytoma syndrome	Enrichment	CDKN2A	1.53
737	Spondyloepimetaphyseal dysplasia, x-linked, with hypomyelinating leukodystrophy	Enrichment	AIFM1	1.53
738	Charcot-marie-tooth disease, x-linked recessive, 4, with or without cerebellar ataxia	Enrichment	AIFM1	1.53
739	Combined oxidative phosphorylation deficiency 6	Enrichment	AIFM1	1.53
740	Melanoma, cutaneous malignant 2	Enrichment	CDKN2A	1.53
741	Deafness, autosomal dominant 64	Enrichment	DIABLO	1.53
742	Melanoma-pancreatic cancer syndrome	Enrichment	CDKN2A	1.53
743	Charcot-marie-tooth disease x-linked recessive 4	Enrichment	AIFM1	1.53
744	Cone-rod dystrophy 6	Enrichment	CACNA1F, CACNA2D4	1.53
745	Congenital myopathy 4a, autosomal dominant	Enrichment	ACTA1, ITGA7	1.51
746	Pseudohypoparathyroidism, type ia	Enrichment	GNAS	1.50
747	Pituitary adenoma 4, acth-secreting	Enrichment	GNAI2	1.50
748	Cutis marmorata telangiectatica congenita	Enrichment	GNA11	1.50
749	Histiocytoma, angiomatoid fibrous	Enrichment	CREB1	1.50
750	Pseudopseudohypoparathyroidism	Enrichment	GNAS	1.50
751	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	1.50
752	Autosomal dominant hypocalcemia	Enrichment	GNA11	1.50
753	Pseudohypoparathyroidism	Enrichment	GNAS	1.50
754	Hypopituitarism	Enrichment	GNAI2	1.50
755	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	1.50
756	Acth-independent macronodular adrenal hyperplasia	Enrichment	GNAS	1.50
757	Cerebral visual impairment	Enrichment	GNB1	1.50
758	Phakomatosis cesioflammea	Enrichment	GNA11	1.50
759	Autoinflammatory disease	Enrichment	TNFRSF1A, XIAP	1.50
760	Fibromatosis, gingival, 1	Enrichment	SOS1	1.49
761	Amelogenesis imperfecta, type ig	Enrichment	PRKAR1A	1.49
762	Thumb deformity	Enrichment	CREBBP	1.49
763	Carotid intimal medial thickness 1	Enrichment	PPARG	1.49
764	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	1.49
765	Marbach-schaaf neurodevelopmental syndrome	Enrichment	PRKAR1B	1.49
766	Menke-hennekam syndrome 2	Enrichment	EP300	1.49
767	Usher syndrome, type iv	Enrichment	PRKAR1A	1.49
768	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	1.49
769	Acrodysostosis	Enrichment	PRKAR1A	1.49
770	Body mass index quantitative trait locus 19	Enrichment	ADCY3	1.49
771	Fibrolamellar carcinoma	Enrichment	PRKACA	1.49
772	Ciliary dyskinesia, primary, 18	Enrichment	PRKAR1B	1.49
773	Isolated primary pigmented nodular adrenocortical disease	Enrichment	PRKAR1A	1.49
774	Familial partial lipodystrophy	Enrichment	PPARG	1.49
775	Developmental and epileptic encephalopathy	Enrichment	ARHGEF15, CACNA1E, CACNA2D2	1.48
776	Spinocerebellar ataxia 17	Enrichment	TBP	1.48
777	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RARB	1.48
778	Intellectual developmental disorder, autosomal dominant 73	Enrichment	TAF4	1.48
779	Dandy-walker syndrome	Enrichment	BRAF, PDGFRB	1.47
780	Epiphyseal dysplasia, multiple, with early-onset diabetes mellitus	Enrichment	EIF2AK3	1.47
781	Pulmonary venoocclusive disease 1, autosomal dominant	Enrichment	EIF2AK4	1.47
782	Premature ovarian failure 3	Enrichment	AGO2	1.47
783	Hyperinsulinemic hypoglycemia, familial, 4	Enrichment	INSR	1.47
784	Pulmonary venoocclusive disease 2, autosomal recessive	Enrichment	EIF2AK4	1.47
785	Maturity-onset diabetes of the young, type 10	Enrichment	INS	1.47
786	Intellectual developmental disorder, autosomal recessive 67	Enrichment	EIF3F	1.47
787	Genitourinary and/or brain malformation syndrome	Enrichment	PPP1R12A	1.47
788	Hyperproinsulinemia	Enrichment	INS	1.47
789	Neurodevelopmental disorder with language delay and behavioral abnormalities, with or without seizures	Enrichment	AGO1	1.47
790	Leukoencephalopathy with vanishing white matter 4	Enrichment	EIF2B4	1.47
791	Pulmonary venoocclusive disease 1	Enrichment	EIF2AK4	1.47
792	Pulmonary venoocclusive disease 2	Enrichment	EIF2AK4	1.47
793	Leukodystrophy, hypomyelinating, 17	Enrichment	EIF2AK1	1.47
794	Diabetes mellitus, permanent neonatal, 4	Enrichment	INS	1.47
795	Pulmonary venoocclusive disease	Enrichment	EIF2AK4	1.47
796	Tafro syndrome	Enrichment	MAP2K2	1.47
797	Immunodeficiency 33	Enrichment	IKBKG	1.47
798	Ectodermal dysplasia and immunodeficiency 2	Enrichment	NFKBIA	1.47
799	Glucosephosphate dehydrogenase deficiency	Enrichment	IKBKG	1.47
800	Immunodeficiency 57 with autoinflammation	Enrichment	RIPK1	1.47
801	Brachydactyly, type a1	Enrichment	GDF5	1.46
802	Achondroplasia	Enrichment	FGFR3	1.46
803	Brachydactyly, type c	Enrichment	GDF5	1.46
804	Hypogonadotropic hypogonadism 2 with or without anosmia	Enrichment	FGFR1	1.46
805	Larsen syndrome	Enrichment	FGFR3	1.46
806	Klippel-feil syndrome 1, autosomal dominant	Enrichment	GDF6	1.46
807	Thyroid carcinoma, familial medullary	Enrichment	NTRK1	1.46
808	Exfoliation syndrome	Enrichment	LTBP2	1.46
809	Tumoral calcinosis, hyperphosphatemic, familial, 1	Enrichment	FGF23	1.46
810	Acromesomelic dysplasia 2a	Enrichment	GDF5	1.46
811	Thrombocythemia 1	Enrichment	THPO	1.46
812	Hypophosphatemic rickets, autosomal dominant	Enrichment	FGF23	1.46
813	Acromesomelic dysplasia 2c	Enrichment	GDF5	1.46
814	Acromesomelic dysplasia 2b	Enrichment	GDF5	1.46
815	Mycosis fungoides	Enrichment	TNFRSF1B	1.46
816	Immunodeficiency 98 with autoinflammation, x-linked	Enrichment	FASLG	1.46
817	Muscular dystrophy, duchenne type	Enrichment	LTBP4	1.46
818	Transposition of the great arteries, dextro-looped	Enrichment	BMP2	1.46
819	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3R1	1.46
820	Chromosome 8p11 myeloproliferative syndrome	Enrichment	FGFR1	1.46
821	Dyskeratosis congenita, autosomal dominant 6	Enrichment	THPO	1.46
822	Neonatal nephrocutaneous inflammatory syndrome	Enrichment	EGFR	1.46
823	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	1.46
824	Weill-marchesani syndrome 1	Enrichment	LTBP2	1.46
825	Autosomal recessive cutis laxa type i	Enrichment	LTBP1	1.46
826	Isolated growth hormone deficiency, type ib	Enrichment	GH1	1.46
827	Loeys-dietz syndrome 1	Enrichment	TGFBR1	1.46
828	Hamartoma	Enrichment	FGFR3	1.46
829	Atypical teratoid rhabdoid tumor	Enrichment	TP53	1.46
830	Anaplastic astrocytoma	Enrichment	TP53	1.46
831	Immunodeficiency 14	Enrichment	PIK3R1	1.46
832	Migraine without aura	Enrichment	TNF	1.46
833	Growth delay due to insulin-like growth factor i resistance	Enrichment	IGF1R	1.46
834	High bone mass osteogenesis imperfecta	Enrichment	BMP1	1.46
835	Neonatal inflammatory skin and bowel disease	Enrichment	EGFR	1.46
836	Geleophysic dysplasia	Enrichment	LTBP3	1.46
837	Renal cell carcinoma	Enrichment	MET	1.46
838	Testicular cancer	Enrichment	FGFR3	1.46
839	Isolated klippel-feil syndrome	Enrichment	GDF6	1.46
840	Beckwith-wiedemann syndrome due to imprinting defect of 11p15	Enrichment	IGF2	1.46
841	Vogt-koyanagi-harada disease	Enrichment	FAS	1.46
842	Saczary syndrome	Enrichment	TNFRSF1B	1.46
843	Anemia, congenital dyserythropoietic, type iiia	Enrichment	RACGAP1	1.45
844	Lethal congenital contracture syndrome 3	Enrichment	PIP5K1C	1.45
845	Neutrophilia, hereditary	Enrichment	PIP4K2B	1.45
846	Neutropenia, severe congenital, 7, autosomal recessive	Enrichment	PIP4K2B	1.45
847	Albinism, oculocutaneous, type ia	Enrichment	NOX4	1.45
848	Immunodeficiency 72 with autoinflammation and lymphoproliferation	Enrichment	NCKAP1	1.45
849	Severe congenital neutropenia 7	Enrichment	PIP4K2B	1.45
850	Intellectual developmental disorder, autosomal dominant 60, with seizures	Enrichment	PIP5K1A	1.45
851	Immune system disease	Enrichment	CDC42	1.45
852	B-lymphoblastic leukemia/lymphoma with hyperdiploidy	Enrichment	PIP4K2A	1.45
853	Immunodeficiency 72	Enrichment	NCKAP1	1.45
854	Type 2 diabetes mellitus	Enrichment	IL6, INSR, PPP1R3A	1.45
855	Precursor t-cell acute lymphoblastic leukemia	Enrichment	ABL1, MYC	1.44
856	Tetralogy of fallot	Enrichment	FLT4, KDR	1.43
857	Aortic aneurysm, familial thoracic 2	Enrichment	ACTA2	1.43
858	Deafness, autosomal dominant 20	Enrichment	ACTG1	1.43
859	Smooth muscle dysfunction syndrome	Enrichment	ACTA2	1.43
860	Aortic aneurysm, familial thoracic 6	Enrichment	ACTA2	1.43
861	Baraitser-winter syndrome 2	Enrichment	ACTG1	1.43
862	Moyamoya disease 5	Enrichment	ACTA2	1.43
863	Noonan syndrome-like disorder with loose anagen hair	Enrichment	PPP1CB	1.43
864	Megacystis-microcolon-intestinal hypoperistalsis syndrome 4	Enrichment	MYL9	1.43
865	Intestinal obstruction	Enrichment	ACTG2	1.43
866	Ataxia-telangiectasia	Enrichment	ATM	1.42
867	Polycythemia vera	Enrichment	ATM	1.42
868	Koolen-de vries syndrome	Enrichment	ATM	1.42
869	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	BCL2	1.42
870	Dedifferentiated liposarcoma	Enrichment	MDM2	1.42
871	Mutilating palmoplantar keratoderma with periorificial keratotic plaques	Enrichment	PERP	1.42
872	T-cell acute lymphoblastic leukemia	Enrichment	BAX	1.42
873	Well-differentiated liposarcoma	Enrichment	MDM2	1.42
874	Spinocerebellar ataxia 29	Enrichment	ITPR1	1.41
875	Visceral neuropathy, familial, 1, autosomal recessive	Enrichment	ERBB3	1.41
876	Timothy syndrome	Enrichment	CACNA1C	1.41
877	Ovarian germ cell cancer	Enrichment	CBL	1.41
878	Night blindness, congenital stationary, type 2a	Enrichment	CACNA1F	1.41
879	Alternating hemiplegia of childhood 1	Enrichment	CACNA1A	1.41
880	Long qt syndrome 8	Enrichment	CACNA1C	1.41
881	Congenital disorder of glycosylation, type iw, autosomal dominant	Enrichment	CACNA1D	1.41
882	Immunodeficiency 52	Enrichment	LAT	1.41
883	Neurodevelopmental disorder with seizures and nonepileptic hyperkinetic movements	Enrichment	CACNA1B	1.41
884	Malignant germ cell tumor of ovary	Enrichment	CBL	1.41
885	Progressive bulbar palsy	Enrichment	CACNA1A	1.41
886	Retinoblastoma	Enrichment	RB1	1.41
887	Dyskeratosis congenita, x-linked	Enrichment	DKC1	1.41
888	Woolly hair, autosomal recessive 3	Enrichment	RB1	1.41
889	Hypotrichosis 8	Enrichment	RB1	1.41
890	Interstitial lung disease	Enrichment	TERT	1.41
891	Macrocytic anemia	Enrichment	TERT	1.41
892	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	ITGB3	1.40
893	Angioedema, hereditary, 1	Enrichment	PLG	1.40
894	Multicentric osteolysis, nodulosis, and arthropathy	Enrichment	MMP2	1.40
895	Muscular dystrophy, congenital, due to integrin alpha-7 deficiency	Enrichment	ITGA7	1.40
896	Epidermolysis bullosa, junctional 6, with pyloric atresia	Enrichment	ITGA6	1.40
897	Bleeding disorder, platelet-type, 24	Enrichment	ITGB3	1.40
898	Alopecia - intellectual disability syndrome	Enrichment	ITGB6	1.40
899	Late-onset retinal degeneration	Enrichment	PLA2G5	1.37
900	Miller-dieker lissencephaly syndrome	Enrichment	YWHAE	1.37
901	Osteogenesis imperfecta, type vi	Enrichment	SERPINF1	1.37
902	Chromosome 17p13.3, centromeric, duplication syndrome	Enrichment	YWHAE	1.37
903	Brittle bone disorder	Enrichment	BMP1, SERPINF1	1.36
904	Sengers syndrome	Enrichment	SLC25A4	1.35
905	Deafness, x-linked 5, with peripheral neuropathy	Enrichment	AIFM1	1.35
906	X-linked deafness 5	Enrichment	AIFM1	1.35
907	Combined oxidative phosphorylation deficiency	Enrichment	AIFM1	1.35
908	Kaposi sarcoma	Enrichment	IL6	1.34
909	Isolated growth hormone deficiency, type ii	Enrichment	GH1	1.34
910	Thyroid cancer, nonmedullary, 1	Enrichment	TP53	1.34
911	Microtia-anotia	Enrichment	BMP5	1.34
912	Glaucoma 3, primary infantile, b	Enrichment	LTBP2	1.34
913	Lymphoproliferative syndrome 2	Enrichment	XIAP	1.34
914	Weill-marchesani syndrome	Enrichment	LTBP2	1.34
915	Embryonal rhabdomyosarcoma	Enrichment	TP53	1.34
916	Aortic aneurysm	Enrichment	TGFBR1	1.34
917	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	KIT	1.34
918	Cerebral malaria	Enrichment	TNF	1.34
919	Silver-russell syndrome due to a point mutation	Enrichment	IGF2	1.34
920	Non-syndromic bicoronal craniosynostosis	Enrichment	FGFR3	1.34
921	Systemic mastocytosis with associated hematologic neoplasm	Enrichment	KIT	1.34
922	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	1.34
923	Mccune-albright syndrome	Enrichment	GNAS	1.33
924	Stuve-wiedemann syndrome 1	Enrichment	IL6ST	1.33
925	Cushing syndrome due to bilateral macronodular adrenocortical disease	Enrichment	GNAS	1.33
926	Melanoma of soft tissue	Enrichment	CREB1	1.33
927	Stüve-wiedemann syndrome	Enrichment	IL6ST	1.33
928	Nuchal bleb, familial	Enrichment	SOS1	1.32
929	Tethered spinal cord syndrome	Enrichment	CREBBP	1.32
930	Frontometaphyseal dysplasia	Enrichment	MAP3K7	1.32
931	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	1.32
932	Myocardial infarction	Enrichment	ITGB3, LTA	1.31
933	Mantle cell lymphoma	Enrichment	ATM	1.30
934	Hemoglobin c disease	Enrichment	CHEK2	1.30
935	Oculomotor apraxia	Enrichment	ATM	1.30
936	Male infertility due to gonadal dysgenesis or sperm disorder	Enrichment	CHEK1	1.30
937	Type 1 diabetes mellitus 2	Enrichment	INS	1.29
938	Menkes disease	Enrichment	EIF2AK3	1.29
939	Heparin cofactor ii deficiency	Enrichment	EIF4G3	1.29
940	Torsion dystonia 1	Enrichment	EIF2AK2	1.29
941	Lessel-kreienkamp syndrome	Enrichment	AGO2	1.29
942	Diffuse gastric and lobular breast cancer syndrome	Enrichment	KRAS	1.29
943	Lynch syndrome 4	Enrichment	RB1	1.29
944	Neurodevelopmental disorder with hypotonia and variable intellectual and behavioral abnormalities	Enrichment	POLR2A	1.29
945	Hereditary ataxia	Enrichment	PRKCG	1.29
946	Pilocytic astrocytoma	Enrichment	KRAS	1.29
947	Granulomatous disease, chronic, autosomal recessive, 2	Enrichment	NCF2	1.28
948	Developmental and epileptic encephalopathy 65	Enrichment	CYFIP2	1.28
949	Amelogenesis imperfecta, type iiia	Enrichment	ITGB6	1.28
950	Epidermolysis bullosa simplex 5c, with pyloric atresia	Enrichment	ITGB4	1.28
951	Retinitis pigmentosa 26	Enrichment	ITGA4	1.28
952	Epidermolytic nevus	Enrichment	HRAS	1.28
953	Aortic aneurysm, familial thoracic 7	Enrichment	MYLK	1.26
954	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	YWHAZ	1.25
955	Arrhythmogenic right ventricular dysplasia, familial, 1	Enrichment	TGFB3	1.24
956	Rhabdomyosarcoma 2	Enrichment	TP53	1.24
957	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	1.24
958	Atrioventricular septal defect	Enrichment	BMP5	1.24
959	Congenital heart defects, multiple types, 4	Enrichment	BMP7	1.24
960	Pre-eclampsia	Enrichment	FLT1	1.24
961	Lymphoma	Enrichment	TP53	1.24
962	Acute myeloid leukemia with maturation	Enrichment	KIT	1.24
963	Juvenile glaucoma	Enrichment	LTBP2	1.24
964	Arrhythmogenic right ventricular dysplasia 1	Enrichment	TGFB3	1.24
965	Vascular dementia	Enrichment	TNF	1.24
966	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	KIT	1.24
967	Diffuse cutaneous systemic sclerosis	Enrichment	CCN2	1.24
968	Centronuclear myopathy	Enrichment	ACTA1, CFL2	1.24
969	Van der woude syndrome 1	Enrichment	CACNA1E	1.24
970	Gillespie syndrome	Enrichment	ITPR1	1.24
971	Nephrotic syndrome, type 3	Enrichment	PLCE1	1.24
972	Primary polycythemia	Enrichment	EPOR	1.24
973	Thyrotoxic periodic paralysis	Enrichment	CACNA1S	1.24
974	Hereditary episodic ataxia	Enrichment	CACNA1A	1.24
975	3-methylglutaconic aciduria, type viii	Enrichment	HTRA2	1.23
976	Rare x-linked non-syndromic sensorineural deafness type dfn	Enrichment	PRPS1	1.23
977	Malaria	Enrichment	IKBKG, TNF	1.23
978	Neuropathy, hereditary sensory and autonomic, type iia	Enrichment	WNK1	1.21
979	Spastic paraplegia 17, autosomal dominant	Enrichment	GNG3	1.21
980	Pseudohypoparathyroidism, type ib	Enrichment	GNAS	1.21
981	Auriculocondylar syndrome 1	Enrichment	GNAI3	1.21
982	Lipodystrophy, congenital generalized, type 2	Enrichment	GNG3	1.21
983	Congenital generalized lipodystrophy	Enrichment	FOS	1.21
984	Hereditary sensory and autonomic neuropathy type 2	Enrichment	WNK1	1.21
985	Familial sick sinus syndrome	Enrichment	GNB2	1.21
986	Macrocephaly/autism syndrome	Enrichment	PTEN	1.21
987	Follicular lymphoma	Enrichment	BCL2	1.21
988	Glioblastoma	Enrichment	ATM	1.21
989	Hemangioma	Enrichment	PTEN	1.21
990	Autosomal thrombocytopenia with normal platelets	Enrichment	CYCS	1.21
991	Lipodystrophy, familial partial, type 3	Enrichment	PPARG	1.20
992	Carney complex variant	Enrichment	PRKAR1A	1.20
993	Arrhythmogenic right ventricular dysplasia, familial, 10	Enrichment	PRKAR1A	1.20
994	Leptin deficiency or dysfunction	Enrichment	PPARG	1.20
995	Gingival fibromatosis	Enrichment	SOS1	1.20
996	Hydrops fetalis, nonimmune	Enrichment	FLT4, HRAS	1.20
997	Idiopathic aplastic anemia	Enrichment	TERT	1.19
998	Alzheimer disease 2	Enrichment	PLAU	1.18
999	Epidermolysis bullosa simplex 1c, localized	Enrichment	ITGB4	1.18
1000	Glanzmann thrombasthenia 2	Enrichment	ITGB3	1.18
1001	Epidermolysis bullosa	Enrichment	ITGA6	1.18
1002	Aplasia cutis congenita	Enrichment	ITGB4	1.18
1003	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	1.17
1004	Neonatal diabetes mellitus	Enrichment	INS	1.17
1005	Craniopharyngioma	Enrichment	BRAF	1.17
1006	Newborn respiratory distress syndrome	Enrichment	BRAF	1.17
1007	Glaucoma, primary open angle	Enrichment	LTBP2	1.17
1008	Split-hand/foot malformation 1	Enrichment	FGFR2	1.17
1009	Wilms tumor, aniridia, genitourinary anomalies, and impaired intellectual development syndrome	Enrichment	BDNF	1.17
1010	Dental anomalies and short stature	Enrichment	LTBP3	1.17
1011	Anterior segment dysgenesis 5	Enrichment	BMP4	1.17
1012	Mitochondrial dna depletion syndrome 1	Enrichment	TYMP	1.17
1013	Limited scleroderma	Enrichment	CCN2	1.17
1014	Classic ehlers-danlos syndrome	Enrichment	TGFBR1	1.17
1015	Cystic fibrosis	Enrichment	PLG, TGFB1	1.16
1016	Knobloch syndrome	Enrichment	PAK2	1.16
1017	Dementia	Enrichment	MAPT	1.15
1018	Endometrial stromal sarcoma	Enrichment	YWHAE	1.15
1019	Nemaline myopathy 2	Enrichment	ACTA1	1.14
1020	Aminoacylase 1 deficiency	Enrichment	ACTB	1.14
1021	Intermediate nemaline myopathy	Enrichment	ACTA1	1.14
1022	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB	1.14
1023	Wilms tumor 5	Enrichment	CHEK2	1.13
1024	Clear cell renal cell carcinoma	Enrichment	ATM	1.13
1025	Migraine, familial hemiplegic, 1	Enrichment	CACNA1A	1.12
1026	Erythrocytosis, familial, 1	Enrichment	EPOR	1.12
1027	Spinocerebellar ataxia 6	Enrichment	CACNA1A	1.12
1028	Aland island eye disease	Enrichment	CACNA1F	1.12
1029	Developmental and epileptic encephalopathy 2	Enrichment	CACNA1A	1.12
1030	Ventricular fibrillation, paroxysmal familial, 1	Enrichment	CACNA1C	1.12
1031	Spinocerebellar ataxia 15	Enrichment	ITPR1	1.12
1032	Barrett esophagus	Enrichment	ERBB2	1.12
1033	Developmental and epileptic encephalopathy 42	Enrichment	CACNA1A	1.12
1034	Cerebellar atrophy with seizures and variable developmental delay	Enrichment	CACNA2D2	1.12
1035	Developmental and epileptic encephalopathy 52	Enrichment	CACNA1A	1.12
1036	Malignant hyperthermia	Enrichment	CACNA1S	1.12
1037	Episodic ataxia	Enrichment	CACNA1A	1.12
1038	Familial or sporadic hemiplegic migraine	Enrichment	CACNA1A	1.12
1039	Pulmonary fibrosis	Enrichment	TERT	1.12
1040	Kidney clear cell sarcoma	Enrichment	TERT	1.12
1041	Capillary malformations, congenital	Enrichment	GNA11	1.11
1042	Night blindness, congenital stationary, type 1c	Enrichment	GNAT1	1.11
1043	Histiocytoid hemangioma	Enrichment	FOS	1.11
1044	Epidermolysis bullosa, junctional 1a, intermediate	Enrichment	ITGB4	1.11
1045	Junctional epidermolysis bullosa non-herlitz type	Enrichment	ITGB4	1.11
1046	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.11
1047	Esophageal cancer	Enrichment	TP53	1.10
1048	Glaucoma 3, primary congenital, a	Enrichment	LTBP2	1.10
1049	Silver-russell syndrome 1	Enrichment	IGF2	1.10
1050	Waardenburg syndrome, type 2e	Enrichment	KITLG	1.10
1051	Hereditary hemorrhagic telangiectasia	Enrichment	GDF2	1.10
1052	Common variable immunodeficiency	Enrichment	NFKB1	1.10
1053	Oligoarticular juvenile idiopathic arthritis	Enrichment	IL2RA	1.10
1054	Overgrowth syndrome	Enrichment	PIK3R1	1.10
1055	Hypophosphatemic rickets	Enrichment	FGF23	1.10
1056	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	IL2RA	1.10
1057	Cardiomyopathy, familial hypertrophic, 1	Enrichment	CACNA1C, RAF1	1.10
1058	Chondrosarcoma, extraskeletal myxoid	Enrichment	TAF15	1.09
1059	Anemia, congenital, nonspherocytic hemolytic, 1	Enrichment	IKBKG	1.08
1060	Spastic ataxia	Enrichment	CACNA1G, CACNB4, ITPR1	1.07
1061	Megacolon	Enrichment	AKT3	1.07
1062	Spherocytosis, type 1	Enrichment	ANK1	1.06
1063	Knobloch syndrome 1	Enrichment	PAK2	1.06
1064	Mosaic variegated aneuploidy syndrome 1	Enrichment	PAK6	1.06
1065	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 1	Enrichment	SLC25A4	1.06
1066	Moyamoya angiopathy	Enrichment	ABL1	1.05
1067	Congenital myopathy 3 with rigid spine	Enrichment	ACTA1	1.05
1068	Coloboma of choroid and retina	Enrichment	ACTG1	1.05
1069	Severe congenital nemaline myopathy	Enrichment	ACTA1	1.05
1070	Arthrogryposis, distal, type 1a	Enrichment	MET	1.05
1071	Isolated growth hormone deficiency, type ia	Enrichment	GH1	1.05
1072	Lymphoma, non-hodgkin, familial	Enrichment	TP53	1.05
1073	Mitochondrial dna depletion syndrome 4b	Enrichment	TYMP	1.05
1074	Epidermolysis bullosa simplex	Enrichment	ITGB4	1.04
1075	Melanoma, uveal	Enrichment	GNA11	1.04
1076	Hypertrichosis	Enrichment	CREBBP	1.03
1077	Episodic ataxia, type 2	Enrichment	CACNA1A	1.03
1078	Heart conduction disease	Enrichment	CACNA1C	1.03
1079	Amblyopia	Enrichment	CACNA1F	1.03
1080	Cardiac arrest	Enrichment	CACNA2D1	1.03
1081	Myeloproliferative neoplasm	Enrichment	CBL	1.03
1082	Congenital short qt syndrome	Enrichment	CACNA2D1	1.03
1083	Aggressive systemic mastocytosis	Enrichment	CBL	1.03
1084	Fraser syndrome 1	Enrichment	GRIP1	1.01
1085	Semantic dementia	Enrichment	MAPT	1.01
1086	Alzheimer's disease 1	Enrichment	APP	1.01
1087	Early-onset autosomal dominant alzheimer disease	Enrichment	APP	1.01
1088	Strabismus	Enrichment	CACNA1A, GNB1	1.01
1089	Orofacial cleft 1	Enrichment	FGF10	1.00
1090	Hypogonadotropic hypogonadism	Enrichment	FGFR1	1.00
1091	Congenital central hypoventilation syndrome	Enrichment	BDNF	1.00
1092	Mitochondrial neurogastrointestinal encephalomyopathy	Enrichment	TYMP	1.00
1093	Hereditary spherocytosis	Enrichment	ANK1	0.99
1094	Renal hypodysplasia/aplasia 1	Enrichment	ITGA8	0.99
1095	Lennox-gastaut syndrome	Enrichment	MAPK10	0.99
1096	Myelofibrosis	Enrichment	SRC	0.98
1097	Brachydactyly	Enrichment	GNAS	0.98
1098	Dystonia	Enrichment	GNAL, GNB1	0.98
1099	Moyamoya disease 1	Enrichment	ACTA2	0.97
1100	Intestinal pseudo-obstruction	Enrichment	ACTG2	0.97
1101	Meier-gorlin syndrome 1	Enrichment	FGFR2	0.95
1102	Peters-plus syndrome	Enrichment	BMP4	0.95
1103	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	0.95
1104	Stickler syndrome	Enrichment	BMP4	0.95
1105	Familial colorectal cancer	Enrichment	TP53	0.95
1106	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3R1	0.95
1107	Primary bone dysplasia	Enrichment	FGFR3	0.95
1108	Hypokalemic periodic paralysis, type 1	Enrichment	CACNA1S	0.95
1109	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1	0.95
1110	Childhood absence epilepsy	Enrichment	CACNA1H	0.95
1111	Gastroesophageal reflux	Enrichment	RPS6KA3	0.94
1112	Orthostatic intolerance	Enrichment	RPS6KA3	0.94
1113	Long qt syndrome 1	Enrichment	CACNA1C, ITPR3	0.93
1114	Connective tissue disease	Enrichment	ACTA2, FGFR3	0.92
1115	Spastic paraplegia 4, autosomal dominant	Enrichment	GNAS	0.92
1116	Hypothyroidism	Enrichment	GNB1	0.92
1117	Choreatic disease	Enrichment	GNAO1	0.92
1118	Polymicrogyria	Enrichment	AKT3	0.92
1119	Pectus excavatum	Enrichment	TGFBR1	0.91
1120	Asthma	Enrichment	TNF	0.91
1121	Myelodysplastic syndrome	Enrichment	TP53	0.91
1122	Osteochondrodysplasia	Enrichment	FGFR3	0.91
1123	Long qt syndrome	Enrichment	CACNA1C, CACNA1S	0.91
1124	Progressive non-fluent aphasia	Enrichment	MAPT	0.91
1125	Behavioral variant of frontotemporal dementia	Enrichment	MAPT	0.91
1126	Childhood-onset nemaline myopathy	Enrichment	ACTA1	0.91
1127	Stroke, ischemic	Enrichment	PRKCH	0.91
1128	Aplastic anemia	Enrichment	TERT	0.91
1129	Ventricular septal defect	Enrichment	RPS6KA3	0.90
1130	Amelogenesis imperfecta, type ie	Enrichment	ITGB6	0.90
1131	Brugada syndrome 1	Enrichment	CACNA2D1	0.89
1132	Permanent neonatal diabetes mellitus	Enrichment	INS	0.89
1133	Systemic lupus erythematosus	Enrichment	ITGAM, TNF	0.88
1134	Cakut	Enrichment	ACTG1, GDF6	0.88
1135	Septooptic dysplasia	Enrichment	FGFR1	0.88
1136	Cutis laxa	Enrichment	LTBP4	0.88
1137	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	TGFB3	0.88
1138	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	TGFB3	0.88
1139	Mosaic variegated aneuploidy syndrome	Enrichment	PAK6	0.87
1140	Neurodegeneration with brain iron accumulation	Enrichment	PLA2G6	0.87
1141	Cornelia de lange syndrome 1	Enrichment	TAF6	0.85
1142	Cornelia de lange syndrome	Enrichment	TAF6	0.85
1143	Amelogenesis imperfecta	Enrichment	LTBP3	0.85
1144	Cardiomyopathy, familial hypertrophic, 4	Enrichment	BRAF	0.84
1145	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	EIF3F	0.84
1146	Coronary heart disease 5	Enrichment	IKBKG	0.84
1147	Alternating hemiplegia of childhood	Enrichment	CACNA1A	0.83
1148	Difference of sex development	Enrichment	CACNA1A	0.83
1149	Achromatopsia	Enrichment	GNAT2	0.83
1150	Cone-rod dystrophy 2	Enrichment	CACNA1F, CACNA2D4, ITGA4	0.83
1151	Frontotemporal dementia 1	Enrichment	MAPT	0.83
1152	Eye disease	Enrichment	CACNA1F, CACNA2D4	0.82
1153	Chronic granulomatous disease	Enrichment	NCF2	0.82
1154	Hypogonadotropic hypogonadism 7 with or without anosmia	Enrichment	FGFR1	0.82
1155	Generalized epilepsy with febrile seizures plus	Enrichment	FGF13	0.82
1156	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	TGFB3	0.82
1157	Leukemia, acute lymphoblastic	Enrichment	CDKN2A	0.82
1158	Mitochondrial myopathy	Enrichment	SLC25A4	0.82
1159	West syndrome	Enrichment	GNAO1, NTRK2	0.81
1160	Familial thoracic aortic aneurysm and dissection	Enrichment	MYLK	0.81
1161	Complex neurodevelopmental disorder	Enrichment	H4C3, H4C5, H4C9, TAF4	0.80
1162	Movement disease	Enrichment	GNAO1	0.79
1163	Sensorineural hearing loss	Enrichment	AIFM1, HGF	0.79
1164	Protein-deficiency anemia	Enrichment	NRAS	0.79
1165	Nephrotic syndrome, type 1	Enrichment	PLCE1	0.79
1166	Seckel syndrome	Enrichment	ATR	0.78
1167	Early-onset parkinson's disease	Enrichment	HTRA2	0.78
1168	Heart disease	Enrichment	ABL1	0.77
1169	Cat eye syndrome	Enrichment	ACTG1	0.77
1170	Nemaline myopathy	Enrichment	ACTA1	0.77
1171	Isolated macular dystrophy	Enrichment	ITGA4	0.76
1172	Osteogenesis imperfecta, type iv	Enrichment	SERPINF1	0.76
1173	Diabetes mellitus	Enrichment	INS	0.76
1174	Lynch syndrome	Enrichment	CHEK2	0.76
1175	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	ADCY1, HGF, MET	0.76
1176	Chromosome 1p36 deletion syndrome	Enrichment	PRKCZ	0.75
1177	Hypertelorism	Enrichment	FGFR2, RPS6KA3	0.74
1178	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	DIABLO, KITLG	0.74
1179	Beckwith-wiedemann syndrome	Enrichment	IGF2	0.72
1180	Human immunodeficiency virus type 1	Enrichment	CXCL12	0.72
1181	Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay	Enrichment	DKC1	0.72
1182	Aortic valve disease 1	Enrichment	SOS1	0.72
1183	Migraine with or without aura 1	Enrichment	CACNA1A	0.71
1184	Epilepsy, myoclonic juvenile	Enrichment	CACNB4	0.71
1185	Epilepsy, idiopathic generalized	Enrichment	CACNA1H	0.71
1186	Combined immunodeficiency	Enrichment	ZAP70	0.71
1187	Combined t cell and b cell immunodeficiency	Enrichment	ZAP70	0.71
1188	Combined t and b cell immunodeficiency	Enrichment	ZAP70	0.71
1189	Microphthalmia/coloboma 12	Enrichment	RARB	0.70
1190	Osteoporosis	Enrichment	SRC	0.70
1191	Ehlers-danlos syndrome	Enrichment	TGFB2	0.70
1192	Interstitial lung disease 2	Enrichment	TERT	0.69
1193	Myopia	Enrichment	SLC25A4	0.69
1194	Premature menopause	Enrichment	EIF2B2	0.69
1195	46,xy partial gonadal dysgenesis	Enrichment	SOS1	0.69
1196	Nephrotic syndrome	Enrichment	ITGA3, PLCE1	0.69
1197	Macs syndrome	Enrichment	GDF6	0.68
1198	Cardiac conduction defect	Enrichment	CACNA1C	0.67
1199	Congenital long qt syndrome	Enrichment	ITPR3	0.67
1200	Heart, malformation of	Enrichment	MAPK1	0.66
1201	Polydactyly, postaxial, type a1	Enrichment	EP300	0.66
1202	Corpus callosum, agenesis of	Enrichment	CREBBP	0.66
1203	Isolated corpus callosum agenesis	Enrichment	CREBBP	0.66
1204	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP	0.66
1205	Esophageal atresia/tracheoesophageal fistula	Enrichment	POLR2B	0.65
1206	Coloboma of macula	Enrichment	RARB	0.65
1207	Visceral heterotaxy	Enrichment	LEFTY2	0.64
1208	Aortic aneurysm, familial thoracic 1	Enrichment	MYLK	0.63
1209	Congenital nervous system abnormality	Enrichment	FGFR3, GNAO1, GNB5	0.63
1210	Nervous system disease	Enrichment	FGFR3, GNAO1, GNB5	0.63
1211	Diamond-blackfan anemia 1	Enrichment	TP53	0.62
1212	Hypertension, essential	Enrichment	GNB3	0.62
1213	Cleft palate, isolated	Enrichment	GNB1	0.62
1214	Early infantile developmental and epileptic encephalopathy	Enrichment	GNAO1	0.60
1215	Syndromic intellectual disability	Enrichment	TAF6	0.60
1216	Anterior segment dysgenesis	Enrichment	ITPR1	0.59
1217	Skin disease	Enrichment	ITGB4	0.59
1218	Leukodystrophy	Enrichment	AIFM1	0.58
1219	Parkinson's disease	Enrichment	TBP	0.56
1220	Neuromuscular disease	Enrichment	ACTA1	0.54
1221	Maturity-onset diabetes of the young	Enrichment	INS	0.53
1222	Parkinson disease, late-onset	Enrichment	MAPT	0.53
1223	Attention deficit-hyperactivity disorder	Enrichment	GNB5	0.53
1224	Congenital myopathy	Enrichment	ACTA1	0.52
1225	Williams-beuren syndrome	Enrichment	LIMK1	0.52
1226	Ear malformation	Enrichment	AIFM1	0.52
1227	Microphthalmia	Enrichment	RARB	0.50
1228	Peripheral nervous system disease	Enrichment	NGF	0.50
1229	Neuropathy	Enrichment	NGF	0.50
1230	Cone dystrophy	Enrichment	GNAT2	0.50
1231	Auditory neuropathy	Enrichment	AIFM1	0.49
1232	Scoliosis	Enrichment	CREBBP	0.49
1233	Severe covid-19	Enrichment	ITGAV	0.49
1234	Lissencephaly	Enrichment	ACTG1	0.49
1235	Focal segmental glomerulosclerosis	Enrichment	PLCE1	0.49
1236	Developmental and epileptic encephalopathy 1	Enrichment	GNAO1	0.48
1237	Diamond-blackfan anemia	Enrichment	TP53	0.46
1238	Primary ciliary dyskinesia	Enrichment	DRC4, PRKAR1B	0.46
1239	Mitochondrial disease	Enrichment	GFER, SLC25A4	0.43
1240	Dilated cardiomyopathy	Enrichment	BRAF, RAF1	0.39
1241	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.38
1242	Non-syndromic x-linked intellectual disability	Enrichment	RPS6KA3	0.38
1243	Primary autosomal recessive microcephaly	Enrichment	TAF13	0.38
1244	Left ventricular noncompaction	Enrichment	RAF1	0.36
1245	Genetic steroid-resistant nephrotic syndrome	Enrichment	ARHGDIA	0.32
1246	Hypertrophic cardiomyopathy	Enrichment	SLC25A4	0.32
1247	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	FGF8	0.32
1248	Non-syndromic genetic deafness	Enrichment	ACTG1	0.31
1249	Fetal akinesia deformation sequence 1	Enrichment	ACTA1	0.30
1250	Autism spectrum disorder	Enrichment	GNB1, MEF2C	0.29
1251	Myopathy	Enrichment	ACTA1	0.28
1252	Distal arthrogryposis	Enrichment	ACTA1	0.26
1253	Nonsyndromic hearing loss	Enrichment	ACTG1	0.26
1254	Charcot-marie-tooth disease	Enrichment	ARHGEF10	0.25
1255	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	MAPT	0.24
1256	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	0.24
1257	Optic atrophy plus syndrome	Enrichment	CACNA1F	0.23
1258	Leber plus disease	Enrichment	GDF6	0.17
1259	Autism	Enrichment	CREBBP	0.16
1260	Rare genetic deafness	Enrichment	ACTG1	0.11
1261	Hereditary retinal dystrophy	Enrichment	GNAT1, GNAT2, ITGA4, TIMP3	0.10
1262	Fundus dystrophy	Enrichment	GNAT1, GNAT2, ITGA4, TIMP3	0.10
1263	Retinitis pigmentosa	Enrichment	CACNA1F, CACNA2D4	0.03

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Apoptotic Pathways in Synovial Fibroblasts

Pathway Network for Apoptotic Pathways in Synovial Fibroblasts

Pathway network for the Apoptotic Pathways in Synovial Fibroblasts SuperPath

Member Pathways for Apoptotic Pathways in Synovial Fibroblasts

Pathways in the Apoptotic Pathways in Synovial Fibroblasts SuperPath

Gene overlap in member pathways for Apoptotic Pathways in Synovial Fibroblasts SuperPath

Associated Genes for Apoptotic Pathways in Synovial Fibroblasts

Associated Disorders for Apoptotic Pathways in Synovial Fibroblasts

Disorders associated with Apoptotic Pathways in Synovial Fibroblasts SuperPath

STRING Interaction Network for Apoptotic Pathways in Synovial Fibroblasts

Sources for Apoptotic Pathways in Synovial Fibroblasts